Chinese Journal of Natural Medicines

Papers
(The median citation count of Chinese Journal of Natural Medicines is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Natural-derived drug carriers (NDDCs) for precision therapy141
Multidrug resistance reversal effect of tenacissoside I through impeding EGFR methylation mediated by PRMT1 inhibition81
Targeting the biological activity and biosynthesis of hyperforin: a mini-review32
Therapeutic potential of Ziziphora clinopodioides in cardiovascular diseases: a review22
Dihydroartemisinin attenuates ischemia/reperfusion-induced renal tubular senescence by activating autophagy21
Bavachin induces apoptosis in colorectal cancer cells through Gadd45a via the MAPK signaling pathway19
Dendrobium nobile protects against ovalbumin-induced allergic rhinitis by regulating intestinal flora and suppressing lung inflammation18
Penicipenoids A−G, antioxidant and anti-inflammatory cadinane sesquiterpenoids with rearranged carbon skeletons from the marine sponge symbiotic Penicillium sp. 597517
Design and synthesis of novel saponin-triazole derivatives in the regulation of adipogenesis15
Ephedra Herb extract ameliorates adriamycin-induced nephrotic syndrome in rats via the CAMKK2/AMPK/mTOR signaling pathway14
Inonotus obliquus (Chaga) against HFD/STZ-induced glucolipid metabolism disorders and abnormal renal functions by regulating NOS-cGMP-PDE5 signaling pathway14
A CYP80B enzyme from Stephania tetrandra enables the 3'-hydroxylation of N-methylcoclaurine and coclaurine in the biosynthesis of benzylisoquinoline alkaloids13
Glasesterterpenoids A−C: three sesterterpenoids with 7-cyclohexyldecahydronaphthalene carbon skeleton isolated from the root of Lindera glauca12
Repurposing diacerein to suppress colorectal cancer growth by inhibiting the DCLK1/STAT3 signaling pathway12
Taohe Chengqi decoction inhibits PAD4-mediated neutrophil extracellular traps and mitigates acute lung injury induced by sepsis12
Five Rutaceae family ethanol extracts alleviate H2O2 and LPS-induced inflammation via NF-κB and JAK-STAT3 pathway in HaCaT cells12
Neutrophil CC1 plays a protective role in orthotopic liver transplantation: views from the perspective of natural compounds12
Anti-cancer and anti-inflammatory effects of flavan-4-ol and flavan glycosides from the roots of Pronephrium penangianum11
Ginsenoside Rb1 improves brain, lung, and intestinal barrier damage in middle cerebral artery occlusion/reperfusion (MCAO/R) micevia the PPARγ signaling pathway11
Pure drug nanomedicines - where we are?11
Research progress on new techniques and methods for identifying active ingredients in traditional Chinese medicine11
New di-spirocyclic labdane diterpenoids from the aerial parts of Leonurus japonicus10
Progress in approved drugs from natural product resources10
De novo production of 24-epi-ergosterol in bioengineered yeast10
Covalent flavoproteins: types, occurrence, biogenesis and catalytic mechanisms10
Network pharmacology and AI: illuminating the path to precision herbal medicine in Ganoderma spp.9
Identification of natural product-based drug combination (NPDC) using artificial intelligence9
Atractylodimers A−D, unprecedented sesquiterpenoid dimers with cage-like skeletons from Atractylodes macrocephala and their neuroprotective activities9
First-in-class drug oroxylin A tablets for treating hepatic and gastrointestinal disorders: from preclinical development to clinical research9
Guijiajiao (Colla Carapacis et Plastri, CCP) prevents male infertility via gut microbiota modulation9
The ethyl acetate extract of Schefflera kwangsiensis ameliorates oxaliplatin-induced peripheral neuropathic pain via SERCA2b9
Ginkgo biloba extract protects against depression-like behavior in mice through regulating gut microbial bile acid metabolism9
TSZAF monomer combination downregulates the Wnt/β-catenin signaling pathway and inhibits neutrophil recruitment to prevent lung cancer metastasis9
Five new terpenoids from Viburnum odoratissimum var. sessiliflorum9
Transdermal delivery of natural products against atopic dermatitis9
Potential role of the protein interactome in translating TCM theory and clinical practice into modern biomedical knowledge9
Neuroprotective and antidiabetic lanostane-type triterpenoids from the fruiting bodies of Ganoderma theaecolum9
Discovery of fernane-type triterpenoids from Diaporthe discoidispora using genome mining and HSQC-based SMART technology8
Four new diphenyl ether derivatives from a mangrove endophytic fungus Epicoccum sorghinum8
Dimeric sesquiterpenoids with anti-inflammatory activities from Inula britannica8
Cytotoxic lignans from the roots and rhizomes of Diphylleia sinensis, a China’s endemic plant species8
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo8
An overview of the advantageous effects and underlying mechanisms of natural polysaccharides in inflammatory bowel disease8
Talaketides A−G, linear polyketides with prostate cancer cytotoxic activity from the mangrove sediment-derived fungus Talaromyces sp. SCSIO 410278
The chemical structures, biosynthesis, and biological activities of secondary metabolites from the culinary-medicinal mushrooms of the genus Hericium: a review8
Saponins from Aralia taibaiensis protect against brain ischemia/reperfusion injuries by regulating the apelin/AMPK pathway8
Study on the dynamic variation of the secondary metabolites in Viscum coloratum using targeted metabolomics8
Stem-leaf saponins of Panax notoginseng attenuate experimental Parkinson's disease progression in mice by inhibiting microglia-mediated neuroinflammation via P2Y2R/PI3K/AKT/NFκB signaling pathway8
Natural products targeting NLRP3 inflammasome for metabolic dysfunction-associated fatty liver disease: the known unknowns8
KG-CNNDTI: a knowledge graph-enhanced prediction model for drug-target interactions and application in virtual screening of natural products against Alzheimer’s disease7
Eudesmane-guaiane sesquiterpenoid dimers from Aucklandia costus trigger paraptosis-like cell death via ROS accumulation and MAPK hyperactivation7
SBC (Sanhuang Xiexin Tang combined with Baihu Tang plus Cangzhu) alleviates NAFLD by enhancing mitochondrial biogenesis and ameliorating inflammation in obese patients and mice7
Intervention of natural products targeting novel mechanisms after myocardial infarction7
Identification and screening of bioactive peptides against nephropathy derived from Mantidis Oötheca based on complement C3 inhibition7
The extract of Cyperus rotundus rhizome promotes hair growth and modulates hair cycle in vivo and in vitro7
Dammarane-type triterpenoid saponins isolated from Gynostemma pentaphyllum ameliorate liver fibrosis via agonizing PP2Cα and inhibiting deposition of extracellular matrix7
Natural diosmin alleviating obesity and nonalcoholic fatty liver disease by regulating the activating the AMP-activated protein kinase (AMPK) pathway7
Artemdubinoids A–N: novel sesquiterpenoids with antihepatoma cytotoxicity from Artemisia dubia7
Structurally diverse terpenoids from Pseudotsuga brevifolia and their inhibitory effects against ACL and ACC1 enzymes7
Anti-inflammatory effects of aucubin in cellular and animal models of rheumatoid arthritis7
Pulchinenoside B4 attenuates gouty arthritis by regulating NLRP3 inflammasome and macrophage polarization: a transcriptomics-based analysis7
Antimicrobial indole alkaloids from Tabernaemontana corymbosa7
Thirteen new peptaibols with antimicrobial activities from Trichoderma sp.7
Rehmanniae Radix Praeparata aqueous extract improves hepatic ischemia/reperfusion injury by restoring intracellular iron homeostasis7
A polysaccharide from Arthrospira platensis alleviates pancreatic cancerassociated with negatively regulating galectin-3 and glypican-6 expression7
Anti-pseudo-allergic components in licorice extract inhibit mast cell degranulation and calcium influx6
New pimarane diterpenoids with antibacterial activity from fungus Arthrinium sp. ZS036
Abietane diterpenoids and iridoids from Caryopteris mongolica6
A comprehensive review of natural products with anti-hypoxic activity6
Anti-hepatitis B virus activities of natural products and their antiviral mechanisms6
NO inhibitory constituents from Glycosmis craibii var. glabra6
Protective mechanisms of Qingda granule in hypertensive kidney injury: Focus on ERK/RSK1-mediated mitochondrial protection6
Leveraging microbial natural products for pharmaceutical innovation: a vision of inspiration and future prospects6
Esculetin triggers ferroptosis via inhibition of the Nrf2-xCT/GPx4 axis in hepatocellular carcinoma6
Huatuo Zaizao Pills improve myocardial ischemia by inhibiting extracellular calcium influx6
Diverse sesquiterpenoids from Litsea lancilimba Merr. with potential neuroprotective effects against H2O2-induced SH-SY5Y cell injury6
10,11-Dehydrocurvularin attenuates inflammation by suppressing NLRP3 inflammasome activation6
Structure-guided isolation of anti-neuroinflammatory sesquiterpene coumarins from Ferula sinkiangensis6
Silibinin meglumine ameliorates hepatic encephalopathy via inhibiting UCP2-mediated oxidative stress and mitochondrial dysfunction5
Atractylodis Rhizoma-Atractylodis Macrocephala Rhizoma herbal pair restores intestinal mucosal barrier function in ulcerative colitis via activating Epac1/Rap1 pathway and inhibiting PI3K/AKT pathway5
Anti-inflammatory germacrane-type sesquiterpene lactones from Vernonia sylvatica5
Five new spirosterol saponins from Allii Macrostemonis Bulbus5
Ginsenoside-Rg1 combined with a conditioned medium from induced neuron-like hUCMSCs alleviated the apoptosis in a cell model of ALS through regulating the NF-κB/Bcl-2 pathway5
Wenxia Changfu Formula inhibits NSCLC metastasis by halting TAMs-induced epithelial-mesenchymal transition via antagonisticallymodulating CCL185
Exosomes derived from Nr-CWS pretreated MSCs facilitate diabetic wound healing by promoting angiogenesis via the circIARS1/miR-4782-5p/VEGFA axis5
NUMB endocytic adaptor protein (NUMB) mediates the anti-hepatic fibrosis effect of artesunate (ART) by inducing senescence in hepatic stellate cells (HSCs)5
Potential role of Natural Herbal Tea as a healthy beverage in reducing the risk of liver cancer and chronic liver disease mortality5
Paeoniflorin alleviates depression by inhibiting the activation of NLRP3 inflammasome via promoting mitochondrial autophagy5
Korean red ginseng alleviates benign prostatic hyperplasia by dysregulating androgen receptor signaling and inhibiting DRP1-mediated mitochondrial fission5
Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro5
TCM network pharmacology: new perspective integrating network target with artificial intelligence and multi-modal multi-omics technologies5
Taohong Siwu Decoction: a classical Chinese prescription for treatment of orthopedic diseases5
Pinelliae Rhizoma: a systematic review on botany, ethnopharmacology, phytochemistry, preclinical and clinical evidence5
Structurally diverse sesquiterpenoids with anti-MDR cancer activity from Penicillium roqueforti5
A comprehensive review on wedelolactone: natural sources, total synthesis, and pharmacological activities5
Chemical composition-based characterization of the anti-allergic effect of Guominkang Formula on IgE-mediated mast cells activation and passive cutaneous anaphylaxis5
Therapeutic potential and mechanism of Chinese herbal medicines in treating fibrotic liver disease5
Nigella sativa L. seed extract alleviates oxidative stress-induced cellular senescence and dysfunction in melanocytes5
MolP-PC: a multi-view fusion and multi-task learning framework for drug ADMET property prediction4
Houttuynia cordata polysaccharides alleviate ulcerative colitis by restoring intestinal homeostasis4
Commentary on “A population of stem cells with strong regenerative potential discovered in deer antlers ”4
The signaling pathways of atherosclerosis regulated by Taohong Siwu Decoction4
Deep chemical identification of phytoecdysteroids in Achyranthes bidentata Blume by UHPLC coupled with linear ion trap-Orbitrap mass spectrometry and targeted isolation4
Loganin inhibits the ROS-NLRP3-IL-1β axis by activating the NRF2/HO-1 pathway against osteoarthritis4
Naturally derived oncolytic peptides: from discovery to clinical translation4
Puerarin inhibits inflammation and lipid accumulation in alcoholic liver disease through regulating MMP84
Structurally diverse rhamnofolane, tigliane, and daphnane diterpenoids from Euphorbia wallichii as anti-liver fibrosis agents4
Exploring artificial intelligence approaches for predicting synergistic effects of active compounds in traditional Chinese medicine based on molecular compatibility theory4
Geranylated or prenylated flavonoids from Cajanus volubilis4
Comprehensive analysis of the antibacterial activity of 5,8-dihydroxy-1,4-naphthoquinone derivatives against methicillin-resistant Staphylococcus aureus4
The combination of EGCG with warfarin reduces deep vein thrombosis in rabbits through modulating HIF-1α and VEGF via the PI3K/AKT and ERK1/2 signaling pathways4
Isodons A−H, seco-abietane and abietane-type diterpenoids from Isodon lophanthoides: isolation, structural elucidation, and anti-cholestatic activity4
Evaluation of pharmacokinetics and metabolism of three marine-derived piericidins for guiding drug lead selection4
New nor-ent-halimane and nor-clerodane diterpenes from Callicarpa integerrima with anti-MRSA activity4
Micranthin B alleviates metabolic dysfunction-associated steatohepatitis by targeting G3BP1 to improve stress granule-mediated endoplasmic reticulum stress4
Unveiling the therapeutic mechanism of Epimedium Herba on prostate cancer through network pharmacology and experimental validation4
Xanthones from Garcinia pedunculata and Garcinia nujiangensis and their anti-inflammatory activity4
Herbal medicines for insomnia through regulating 5-hydroxytryptamine receptors: a systematic review4
Heterologous production of bioactive xenoacremone analogs in Aspergillus nidulans4
Potassium dehydroandrographolide succinate regulates the MyD88/CDH13 signaling pathway to enhance vascular injury-induced pathological vascular remodeling4
Integrative SMRT sequencing and ginsenoside profiling analysis provide insights into the biosynthesis of ginsenoside in Panax quinquefolium4
Effect and mechanism of Chinese medicine on inhibiting the senescence of mesenchymal stem cells4
Research progress of 3-n-butylphthalide and its derivatives in combating cerebral ischemia4
Five new meroterpenoids from Rhododendron anthopogonoides and their anti-inflammatory activity4
Caerulomycin A disrupts glucose metabolism and triggers ER stress-induced apoptosis in triple-negative breast cancer cells3
Combination strategies for first-line treatment of patients with unresectable hepatocellular carcinoma: prospect of natural products3
Rapid identification of stigmastane-type steroid saponins from Vernonia amygdalina leaf based on α-glucosidase inhibiting activity and molecular networking3
A naturally derived small molecule compound suppresses tumor growth and metastasis in mice by relieving p53-dependent repression of CDK2/Rb signaling and the Snail-driven EMT3
Design and synthesis of antiviral pseudo-natural products through effective one-step acylmethylation macrocyclization3
Oroxyloside protects against dextran sulfate sodium-induced colitis by inhibiting ER stress via PPARγ activation3
Ustusolate E and 11α-Hydroxy-Ustusolate E induce apoptosis in cancer cell lines by regulating the PI3K/AKT/mTOR and p-53 pathways3
Macrocyclic trichothecenes from Myrothecium verrucaria PA 57 and their cytotoxic activity3
Deciphering chemical and metabolite profiling of Chang-Kang-Fang by UPLC-Q-TOF-MS/MS and its potential active components identification3
Jujuboside A inhibits oxidative stress damage and enhances immunomodulatory capacity of human umbilical cord mesenchymal stem cells through up-regulating IDO expression3
New meroterpenoids featuring a rare 3/5/6/6/11/6/6 fused-ring skeleton from Penicillium brefeldianum SMU03 and their antifibrotic activities3
Discovery and bioassay of disubstituted β-elemene-NO donor conjugates: synergistic enhancement in the treatment of leukemia3
A review of structural modification and biological activities of oleanolic acid3
Advances in modulating the in vivo fate and therapeutic efficacy of mesenchymal stem cells with natural products3
Cytotoxic anthrone–cyclopentenone heterodimers from the fungus Penicillium sp. guided by molecular networking3
Asponchimides A−E: new enantiomeric N-acetyldopamine trimers from Aspongopus chinensis3
Functional characterization of CYP81C16 involved in the tanshinone biosynthetic pathway in Salvia miltiorrhiza3
Traditional Chinese medicine enables the development of small-molecule inhibitors of HSP47, future therapeutic implication in venous thromboembolism3
Xenopus GLP-1-based glycopeptides as dual glucagon-like peptide 1 receptor/glucagon receptor agonists with improved in vivo stability for treating diabetes and obesity3
Periplaneta americana extract promotes infectious diabetic ulcers wound healing by downregulation of LINC01133/SLAMF93
Cyclocarysaponins A–J, dammarane-type triterpenoid glycosides from the leaves of Cyclocarya paliurus3
Advances in the combination of stem cell exosomes with medical devices-the new direction for combination products3
Combining label-free quantitative proteomics and 2D-DIGE to identify the potential targets of Sini Decoction acting on myocardial infarction3
Recent advances in the culture-independent discovery of natural products using metagenomic approaches3
Gambogic acid suppresses pancreatic fibrosis via inhibiting YAP1-mediated activation of pancreatic stellate cells3
Genome mining of fungal globin-like enzymes for catalyzing the synthesis of linear terpenes3
Potential therapeutic benefits of Murraya exotica L. extract on type II collagen-induced arthritis3
The novel combination of astragaloside IV and formononetin protects from doxorubicin-induced cardiomyopathy by enhancing fatty acid metabolism3
Hypericum monogynum extract inhibits human aortic valve interstitial cell calcification by interfering with the EGFR/PI3K/AKT signaling pathway3
Er-xian ameliorates myocardial ischemia-reperfusion injury in rats through RISK pathway involving estrogen receptors3
New prenylated flavonoid glycosides derived from Epimedium wushanense by β-glucosidase hydrolysis and their testosterone production-promoting effects3
Sustainable utilization of precious Chinese medicines: challenges and the road ahead3
Centranthera grandiflore alleviates alcohol-induced oxidative stress and cell apoptosis3
Research advances in the treatment of arthritis from natural products (2014−present)3
New acylphloroglucinol-sesquiterpenoid adducts with antiviral activities from Dryopteris atrata3
Structural basis of the major TMPRSS2 promoter G-quadruplex and its complex with berberine3
The biologically and ecologically important natural products from the Chinese sea hare Bursatella leachii: structures, stereochemistry and beyond3
Molecular cloning and characterization of three phenylalanine ammonia-lyase genes from Schisandra chinensis3
Discovery of antitumor diterpenoids from Casearia graveolens targeting VEGFR-2 to inhibit angiogenesis3
Natural medicine can substitute antibiotics in animal husbandry: protective effects and mechanisms of rosewood essential oil against Salmonella infection3
Structurally diverse flavonoids from Selaginella doederleinii and their biological activity against laryngeal cancer2
Ultra-warm artificial aerogel fibers: a biomimetic material based on polar bear hair2
Rhubarb in renal fibrosis: from traditional ethnopharmacology to mechanistic therapeutic development2
Mechanism and research progress of improving cartilage injury based on the combination of active ingredients in traditional Chinese medicine and biomaterials2
Naturally occurring seco- and nor-polycyclic polyprenylated acylphloroglucinols: distribution, structural diversity, andbiological activity2
A new phenolic acid isolated from Salvia miltiorrhiza ameliorates OVA-induced allergic asthma by regulation of Th17/Treg cells and inflammation through the TLR4 pathway2
Discovery of proqodine A derivatives with antitumor activity targeting NAD(P)H: quinone oxidoreductase 1 and nicotinamide phosphoribosyltransferase2
Different processing methods and pharmacological effects of Atractylodis Rhizoma2
Exploring the kidney-tonifying effect of Qi-Xian decoction for asthma treatment by modulating the proliferation and migration of endogenous BMSCs2
Protective mechanisms of Leontopodium leontopodioides extracts on lipopolysaccharide-induced acute kidney injury viathe NF-κB/NLRP3 pathway2
Total alkaloids from Thesium chinense inhibit lipopolysaccharide-induced respiratory inflammation by modulating Nrf2/NF-κB/NLRP3 signaling pathway2
Advances in small molecule representations and AI-driven drug research: bridging the gap between theory and application2
Tripterygium hypoglaucum extract ameliorates adjuvant-induced arthritis in mice through the gut microbiota2
Emerging evidence of inter-organ interaction on drug transporters under liver injury2
Synthesis and anti-HIV activities of phorbol derivatives2
Antibacterial and cytotoxic metabolites produced by Streptomyces tanashiensis BYF-112 isolated from Odontotermes formosanus2
Fast-onset antidepressant targeting the nNOS-SERT interaction in the DRN2
Human symbiont Bacteroides xylanisolvens attenuates NASH through intestinal nicotine catabolism2
Toosendanin: upgrade of an old agent in cancer treatment2
Determination of ribose and phosphorus contents in Haemophilus influenzae type b capsular polysaccharide by a quantitative NMR method using a single internal standard2
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway2
Compatibility of cold herb CP and hot herb AZ in Huanglian Ganjiang decoction alleviates colitis mice through M1/M2 macrophage polarization balance via PDK4-mediated glucose metabolism reprogramming2
Paclitaxel anti-cancer therapeutics: from discovery to clinical use2
Pristimerin induces Noxa-dependent apoptosis by activating the FoxO3a pathway in esophageal squamous cell carcinoma2
The transcriptomic-based disease network reveals synergistic therapeutic effect of total alkaloids from Coptis chinensis and total ginsenosides from Panax ginseng on type 2 diabetes mellitus2
Screening the effective components in treating dampness stagnancy due to spleen deficiency syndrome and elucidating the potential mechanism of Poria water extract2
Bisdemethoxycurcumin suppresses liver fibrosis-associated hepatocellular carcinoma via inhibiting CXCL12-induced macrophage polarization2
Activation of NRF2 by celastrol increases antioxidant functions and prevents the progression of osteoarthritis in mice2
Astragali Radix−Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance2
Chemical approaches towards installation of rare functional groups in bacterial surface glycans2
Seven drimane-type sesquiterpenoids from an earwig-associated Aspergillus sp.2
(±)-Talapyrones A−F: six pairs of dimeric polyketide enantiomers with unusual 6/6/6 and 6/6/6/5 ring systems from Talaromyces adpressus2
Approved drugs and natural products at clinical stages for treating Alzheimer’s disease2
Construction and heterologous expression of the di-AFN A1 biosynthetic gene cluster in Streptomyces model strains2
Active herbal ingredients and drug delivery design for tumor therapy: a review2
Andrographolide sulfonate alleviates rheumatoid arthritis by inhibiting glycolysis-mediated activation of PI3K/AKT to restrain Th17 cell differentiation2
Expanding molecular diversity of ribosomally synthesized and post-translationally modified peptide (RiPP) natural products by radical S-adenosylmethionine (SAM) enzymes: recent advances and mechanisti2
Design, synthesis, and biological evaluation of novel chrysin derivatives as poly(ADP-ribose) polymerase 1 (PARP1) inhibitors for the treatment of breast cancer2
Novel phenanthrene/bibenzyl trimers from the tubers of Bletilla striata attenuate neuroinflammation via inhibition of NF-κB signaling pathway2
Steroid and triterpenoid saponins from the rhizomes of Paris polyphylla var. stenophylla2
DeepGCGR: an interpretable two-layer deep learning model for the discovery of GCGR-activating compounds2
Oroxylin A inhibits UVB-induced non-melanoma skin cancer by regulating XPA degradation2
Carrimycin ameliorates lipopolysaccharide and cecal ligation and puncture-induced sepsis in mice2
Identification of a cytochrome P450 from Tripterygium hypoglaucum (Levl.) Hutch that catalyzes polpunonic acid formation in celastrol biosynthesis2
Composition analysis of Compound Shenhua Tablet, a seven-herb Chinese medicine for IgA nephropathy: evaluation of analyte-capacity of the assays2
Protective role of natural products in pulmonary fibrosis through immuneregulation2
Sanguinarine triggers apoptosis and ferroptosis synchronously by directly binding BiP in lung squamous cell carcinoma2
Nuciferine alleviates collagen-induced arthritic in rats by inhibiting the proliferation and invasion of human arthritis-derived fibroblast-like synoviocytes and rectifying Th17/Treg imbalance2
Network pharmacology and experimental validation of Maxing Shigan decoction in the treatment of influenza virus-induced ferroptosis2
Benzyl sulfide, sulfoxide and sulfinate metabolites from Gastrodia elata and their synthesis, derivatization and anti-inflammatory activity2
Diterpenoids and lignans from fossil Chinese medicinal succinum and their activity against renal fibrosis2
Commentary: brain endothelial GSDMD as a novel target for brain disorders associated with BBB damage2
Modern research thoughts and methods on bio-active components of TCM formulae2
Yanggan Jiangmei Formula alleviates hepatic inflammation and lipid accumulation in non-alcoholic steatohepatitis by inhibiting the NF-κB/NLRP3 signaling pathway2
Potential of ginsenoside Rh2and its derivatives as anti-cancer agents2
The circadian clock of anti-tumor immunity2
Recent advances in regulating the cell cycle through inhibiting CDKs for cancer treatment1
Zhongfeng Xingnao Liquid ameliorates post-stroke cognitive impairment through sirtuin1 (SIRT1)/nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase 1 (HO-1) pathway1
Anti-inflammatory sesquiterpene polyol esters from the stem and branch of Tripterygium wilfordii1
Antimalarial and neuroprotective ent-abietane diterpenoids from the aerial parts of Phlogacanthus curviflorus1
Gambogenic acid induces apoptosis via upregulation of Noxa in oral squamous cell carcinoma1
Multioxidized polyketides from an endophytic Penicillium sp. YUD17006 associated with Gastrodia elata1
Natural products: potential therapeutic agents for atherosclerosis1
Buqi-Tongluo Decoction inhibits osteoclastogenesis and alleviates bone loss in ovariectomized rats by attenuating NFATc1, MAPK, NF-κB signaling1
The potential therapeutic role of ginsenosides on fibrosis-associated diseases: a review on molecular mechanisms and call for further research1
Design, synthesis, and bioassay of 5-epi-aminoglycosides1
Predicting cerebral acetylcholine dynamics with huperzine A pharmacokinetics in blood via mPBPK-PD modeling1
Identification of Bulbocodin D and C as novel STAT3 inhibitors and their anticancer activities in lung cancer cells1
Dual-function natural products: Farnesoid X receptor agonist/inflammation inhibitor for metabolic dysfunction-associated steatotic liver disease therapy1
Discovery and characterization of naturally occurring covalent inhibitors of SARS-CoV-2 Mpro from the antiviral herb Ephedra1
Deciphering suppressive effects of Lianhua Qingwen Capsule on COVID-19 and synergistic effects of its major botanical drug pairs1
Effects of traditional Chinese medicine on treatment outcomes in severe COVID-19 patients: a single-centre study1
Luteolin ameliorates ulcerative colitis in mice via reducing the depletion of NCR+ILC3 through Notch signaling pathway1
Effect of astragaloside IV and salvianolic acid B on antioxidant stress and vascular endothelial protection in the treatment of atherosclerosis based on metabonomics1
New tetrahydroanthraquinones and γ-butenolides from the fungus Auxarthron umbrinum DSM31931
Natural products from untapped sources as a potent reserve against antimicrobial resistance crisis1
Dendrobium officinale inhibits colorectal cancer progression by induction of glutathione peroxidase 4-mediated ferroptosis1
Traditional Chinese medicines derived natural inhibitors of ferroptosis on ischemic stroke1
Shionone protects cerebral ischemic injury through alleviating microglia-mediated neuroinflammation1
Capsaicin (CAP) exerts a protective effect against ethanol-induced oxidative gastric mucosal injury by modulating the chemokine receptor 4 (CCR4)/Src/p47phox signaling pathway both in vitro and in viv1
Honokiol attenuates diabetes by enriching Akkermansia muciniphila andregulating tryptophan metabolism in mice1
The extract of Celtis choseniana Nakai alleviates testosterone-induced benign prostatic hyperplasia through inhibiting 5α reductase type 2 and the Akt/NF-κB/AR pathway1
Ten new lignans with anti-inflammatory activities from the leaves of Illicium dunnianum1
Cancer statistics and trends in China: the potential of natural product application1
Research progress on polysaccharides from medicine and food homology materials in functional foods1
Yangxinshi Tablet protects against post-myocardial infarction heart failure with reduced ejection fraction by improving energy metabolism through inhibition of FOXO1/PDK4 signaling1
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