OOIR: Observatory of International Research

Papers

(The TQCC of Current Molecular Pharmacology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Minocycline and Doxycycline: More Than Antibiotics	52
Melatonin Receptor as a Drug Target for Neuroprotection	34
Impact of Sitagliptin on Non-diabetic Covid-19 Patients	33
Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression	26
Oral Administration of the Food-Derived Hydrophilic Antioxidant Ergothioneine Enhances Object Recognition Memory in Mice	25
Molecular Mechanism of a Specific NLRP3 Inhibitor to Alleviate Seizure Severity Induced by Pentylenetetrazole	22
Bacterial Siderophores and Their Potential Applications: A Review	21
Connection between JAK/STAT and PPARγ Signaling During the Progression of Multiple Sclerosis: Insights into the Modulation of T-Cells and Immune Responses in the Brain	20
Alzheimer’s Disease and other Tauopathies: Exploring Efficacy of Medicinal Plant-derived Compounds in Alleviating Tau-mediated Neurodegeneration	19
Salvia miltiorrhiza in Anti-diabetic Angiopathy	17
Therapeutic Potential of Resveratrol in Diabetic Nephropathy According to Molecular Signaling	17
Ginger and Heart Health: From Mechanisms to Therapeutics	17
Quercetin in Attenuation of Ischemic/Reperfusion Injury: A Review	16
Recent Advances in Herbal Nanomedicines for Cancer Treatment	16
Recent Updates in the Alzheimer’s Disease Etiopathology and Possible Treatment Approaches: A Narrative Review of Current Clinical Trials	16
Anticonvulsant, Anxiolytic and Antidepressant Properties of the β-caryophyllene in Swiss Mice: Involvement of Benzodiazepine-GABAAergic, Serotonergic and Nitrergic Systems	16
Drug Repurposing for Cancer Therapy in the Era of Precision Medicine	16
Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway	16
A Review on Post-traumatic Stress Disorder (PTSD): Symptoms, Therapies and Recent Case Studies	15
Apelin/Apelin Receptor System: Molecular Characteristics, Physiological Roles, and Prospects as a Target for Disease Prevention and Pharmacotherapy	15
Statins Attenuate Fibrotic Manifestations of Cardiac Tissue Damage	15
Polyphenols can Potentially Prevent Atherosclerosis and Cardiovascular Disease by Modulating Macrophage Cholesterol Metabolism	15
CircRNA 001418 Promoted Cell Growth and Metastasis of Bladder Carcinoma via EphA2 by miR-1297	15
Caveolin-1: A Promising Therapeutic Target for Diverse Diseases	14
Obesity and Inflammation: Colorectal Cancer Engines	14

Effects of Galbanic Acid on Proliferation, Migration, and Apoptosis of Glioblastoma Cells Through the PI3K/Akt/MTOR Signaling Pathway	14
Hepatic Stellate Cell: A Potential Target for Hepatocellular Carcinoma	14
Pain Perception and Management: Where do We Stand?	14
Interleukin-19 as an Immunoregulatory Cytokine	14
Polyphenols as Potential Therapeutics for Pain and Inflammation in Spinal Cord Injury	14
Ticagrelor Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats by the Inhibition of TGF-β1/Smad3 and PI3K/AKT/mTOR Pathways	13
Curcumin Efficacy in a Serum/Glucose Deprivation-Induced Neuronal PC12 Injury Model	12
Intrathecal Administration of Melatonin Ameliorates the Neuroinflammation- Mediated Sensory and Motor Dysfunction in A Rat Model of Compression Spinal Cord Injury	12
Nf-κb: A Target for Synchronizing the Functioning Nervous Tissue Progenitors of Different Types in Alzheimer's Disease	11
Recent Nanocarrier Approaches for Targeted Drug Delivery in Cancer Therapy	11
Epigenetic Regulation and Promising Therapies in Colorectal Cancer	11
Valproic acid, A Potential Inducer of Osteogenesis in Mouse Mesenchymal Stem Cells	11
Daclatasvir and Sofosbuvir Mitigate Hepatic Fibrosis Through Downregulation of TNF-α / NF-κB Signaling Pathway	11
miR-18a-3p Encourages Apoptosis of Chondrocyte in Osteoarthritis via HOXA1 Pathway	11
Alcoholic Neuropathy: Involvement of Multifaceted Signalling Mechanisms	11
Hypotensive Effects of the Triterpene Oleanolic Acid for Cardiovascular Prevention	10
The Impact of Royal Jelly against Hepatic Ischemia/Reperfusion-Induced Hepatocyte Damage in Rats: The Role of Cytoglobin, Nrf-2/HO-1/COX-4, and P38-MAPK/NF-κB-p65/TNF-α Signaling Pathways	10
Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways	10
Quercetin Inhibits AQP1 Translocation in High-Glucose-Cultured SRA01/04 Cells Through PI3K/Akt/mTOR Pathway	10
Natural Products as PI3K/ Akt Inhibitors: Implications in Preventing Hepatocellular Carcinoma	10
Disruption of Wnt/β-catenin Pathway Elevates the Sensitivity of Gastric Cancer Cells to PD-1 Antibody	10
Quinoa (Chenopodium quinoa Willd.): Exploring a Superfood from Andean Indigenous Cultures with Potential to Reduce Cardiovascular Disease (CVD) Risk Markers	10
Novel Strategy in Breast Cancer Therapy: Revealing The Bright Side of Ginsenosides	10
A Clinical Perspective of Soluble Epoxide Hydrolase Inhibitors in Metabolic and Related Cardiovascular Diseases	10
Bovine lactoferrin as a Modulator of Neuroendocrine Components of Stress	10
Dynamics and Interplay between Autophagy and Ubiquitin-proteasome system Coordination in Skeletal Muscle Atrophy	10
Possibility that the Onset of Autism Spectrum Disorder is Induced by Failure of the Glutamine-Glutamate Cycle	9
Acetate Suppresses Lipopolysaccharide-stimulated Nitric Oxide Production in Primary Rat Microglia but not in BV-2 Microglia Cells	9
Inhibitory Effects of Cathepsin K Inhibitor (ODN-MK-0822) on the Paracrine Pro-Osteoclast Factors of Breast Cancer Cells	9
The Beneficial Effect of Rice Bran Extract Against Rotenone-Induced Experimental Parkinson’s Disease in Rats	9
Immunomodulatory Therapeutic Effects of Curcumin on M1/M2 Macrophage Polarization in Inflammatory Diseases	9
Actions of Alcohol in Brain: Genetics, Metabolomics, GABA Receptors, Proteomics and Glutamate Transporter GLAST/EAAT1	9
The Neuropharmacological Effects of Magnolol and Honokiol: A Review of Signal Pathways and Molecular Mechanisms	9
The Role of miR-129-5p in Cancer: A Novel Therapeutic Target	9
Amygdalin Decreases Adhesion and Migration of MDA-MB-231 and MCF-7 Breast Cancer Cell Lines	9
Wnt/β-catenin Antagonists: Exploring New Avenues to Trigger Old Drugs in Alleviating Glioblastoma Multiforme	8
Quercetin and Glioma: Which Signaling Pathways are Involved?	8
Anti-Inflammatory and Analgesic Effects of Rosehip in Inflammatory Musculoskeletal Disorders and Its Active Molecules	8
Azacitidine, as a DNMT Inhibitor Decreases hTERT Gene Expression and Telomerase Activity More Effective Compared with HDAC Inhibitor in Human Head and Neck Squamous Cell Carcinoma Cell Lines	8
MiR-129-2-3p Inhibits Esophageal Carcinoma Cell Proliferation, Migration, and Invasion via Targeting DNMT3B	8
Flavonoids as Prospective Aromatase Inhibitors in Breast Cancer Prevention/ Therapy	8
Exploring Molecular Approaches in Amyotrophic Lateral Sclerosis: Drug Targets from Clinical and Pre-Clinical Findings	8
DNA Methylation in Epithelial Ovarian Cancer: Current Data and Future Perspectives	7
Gamma-Tocotrienol Synergistically Promotes the Anti-proliferative and Pro-apoptotic Effects of Etoposide on Breast Cancer Cell Lines	7
Harnessing the Natural Pool of Polyketide and Non-ribosomal Peptide Family: A Route Map towards Novel Drug Development	7
Berberine: Is it a Promising Agent for Mental Disorders Treatment?	7
Retinoprotective Effects Of Crocin And Crocetin via Anti-Angiogenic Mechanism in High Glucose-Induced Human Retinal Pigment Epithelium Cells	7
Protective Potential of Ginkgo biloba Against an ADHD-like Condition	7
DoE Based Optimization and Development of Spray-Dried Chitosan-Coated Alginate Microparticles Loaded with Cisplatin for the Treatment of Cervical Cancer	7
PiWi RNA in Neurodevelopment and Neurodegenerative Disorders	7

Agomelatine: An Astounding Sui-generis Antidepressant?	7
Suppression of Molecular Targets and Antiproliferative Effect of Citronellal on Triple-Negative Breast Cancer Cells	7
Resveratrol Augments Doxorubicin and Cisplatin Chemotherapy: A Novel Therapeutic Strategy	7
Targeting Signaling Pathway by Curcumin in Osteosarcoma	7
Mechanism Involved in Fortification by Berberine in CDDP-Induced Nephrotoxicity	7
TRPC3-Based Protein Signaling Complex as a Therapeutic Target of Myocardial Atrophy	7
Lactoferrin Suppresses Decreased Locomotor Activities by Improving Dopamine and Serotonin Release in the Amygdala of Ovariectomized Rats	7
TRIM65 in White Matter Lesions, Innate Immunity, and Tumor	7
Coenzyme Q10 Supplement Rescues Postovulatory Oocyte Aging by Regulating SIRT4 Expression	7
Dihydrotestosterone Induces Chemo-Resistance of Triple-Negative Breast MDA-MB-231 Cancer Cells Towards Doxorubicin Independent of ABCG2 and miR-328-3p	7
Hepatoprotective Effect of Myricetin following Lipopolysaccharide/DGalactosamine: Involvement of Autophagy and Sirtuin 1	6
H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma	6
Pretreatment with Gallic Acid Mitigates Cyclophosphamide Induced Inflammation and Oxidative Stress in Mice	6
Determining the Relative Gene Expression Level of Hypoxia Related Genes in Different Cancer Cell Lines	6
Diallyl Disulfide Attenuates Methotrexate-Induced Hepatic Oxidative Injury, Inflammation and Apoptosis and Enhances its Anti-Tumor Activity	6
Dual Targeting of Autophagy and NF-κB Pathway by PPARγ Contributes to the Inhibitory Effect of Demethoxycurcumin on NLRP3 Inflammasome Priming	6
Exploring the Mitochondrial Apoptotic Cell Death Landscape and Associated Components Serving as Molecular Targets, Primarily for Synthetic and Natural Drugs Targeting Oncology Therapeutics	6
Cytochrome bc1-aa3 Oxidase Supercomplex As Emerging and Potential Drug Target Against Tuberculosis	6
Evaluation of the Effects of 1,25 Vitamin D3 on Regulatory T Cells and T Helper 17 Cells in Vitamin D-deficient Women with Unexplained Recurrent Pregnancy Loss	6
Exercise and Nutraceuticals: Eminent Approach for Diabetic Neuropathy	6
Dantrolene Potentiates the Antineoplastic Effect of Sorafenib in Hepatocellular Carcinoma via Targeting Ca+2/PI3K Signaling Pathway	6