Current Molecular Pharmacology

Article	Citations
Pain Perception and Management: Where do We Stand?	87
RNA Interference-based Therapies for the Reduction of Cardiovascular Risk	67
Deregulated MicroRNAs involved in P53 Signaling Pathway in Breast Cancer with Focus on Triple-negative Breast Cancer	55
Targeting of Lysosomes as a Therapeutic Target in Cancer	38
Protective Effects of Antrodia cinnamomea and Its Constituent Compound Dehydroeburicoic Acid 32 Against Alcoholic Fatty Liver Disease	37
Chimeric Antigen Receptor T-cells (CARs) in Cancer Treatment	35
Mutations in Rv0678, Rv2535c, and Rv1979c Confer Resistance to Bedaquiline in Clinical Isolates of Mycobacterium Tuberculosis	33
Alzheimer’s Disease and other Tauopathies: Exploring Efficacy of Medicinal Plant-derived Compounds in Alleviating Tau-mediated Neurodegeneration	33
Humanin Ameliorates Late-onset Hypogonadism in Aged Male Rats	31
Obesity and Inflammation: Colorectal Cancer Engines	28
Adipose Tissue Dysfunction Following Trauma and Hypoxia Increases the Risk of Post-Surgical Adhesion: Potential for Therapeutic Interventions	28
Dapagliflozin Protects H9c2 Cells Against Injury Induced by Lipopolysaccharide via Suppression of CX3CL1/CX3CR1 Axis and NF-κB Activity	28
Grp94 Inhibitor HCP1 Suppressed the Replication of SVA in BHK-21 Cells and PK-15 Cells	28
A Deeply Quiescent Subset of CML LSC depend on FAO yet Avoid Deleterious ROS by Suppressing Mitochondrial Complex I	25
Recombinant Human Regenerating Gene 4 Attenuates the Severity of Osteoarthritis by Promoting the Proliferation of Articular Chondrocyte in an Animal Model	24
Anticancer Properties of Baicalin against Breast Cancer and other Gynecological Cancers: Therapeutic Opportunities based on Underlying Mechanisms	24
Cytotoxic and Antitumoral Activity of N-(9H-purin-6-yl) Benzamide Derivatives and Related Water-soluble Prodrugs	23
Effects of Modafinil (Provigil) on Memory and Learning in Experimental and Clinical Studies: From Molecular Mechanisms to Behaviour Molecular Mechanisms and Behavioural Effects	23
Large language models in drug development: Current progress and future directions	23
Mechanism, Potential, and Concerns of Immunotherapy for Hepatocellular Carcinoma and Liver Transplantation	22
Assessment of Antioxidant Effect of Beta-Glucan on the Whole Blood Oxidative DNA Damage with the Comet Assay in Colorectal Cancer	19
Cryptotanshinone Induces Necroptosis Through Ca2+ Release and ROS Production in vitro and in vivo	19
Promising Anticancer Activity of Multitarget Cyclin Dependent Kinase Inhibitors against Human Colorectal Carcinoma Cells	19
Targeting FGFR3 is a Useful Therapeutic Strategy for Rheumatoid Arthritis Treatment	19
Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways	18

The Involvement of the NEAT1-1/miR-873-5p/GalNAcT-I Axis in the Development of Neuroblastoma	17
BAPST. A Combo of Common Use Drugs as Metabolic Therapy for Cancer: A Theoretical Proposal	17
Prevalence of Hepatocellular Carcinoma in Men and the Contribution of Androgen and its Receptor in Pathogenesis and Therapy	17
PIASA, A Novel Peptide, Prevents SH-SY5Y Neuroblastoma Cells against Rotenone-induced Toxicity	17
Exploring the Immune-Related Molecular Mechanisms Underlying the Comorbidity of Temporal Lobe Epilepsy and Major Depressive Disorder through Integrated Data Set Analysis	17
Ginger and Heart Health: From Mechanisms to Therapeutics	16
A Review of the Dual Role of MicroRNA-21 in Cardiovascular Diseases: Risk Factor or a Potential Therapeutic Target	16
BBOX1-AS1 Activates Hedgehog Signaling Pathway to Facilitate the Proliferation and Stemness of Esophageal Squamous Cell Carcinoma Cells via miR-506-5p/EIF5A/PTCH1 Axis	15
The Therapeutic Effect and Mechanism of Qishen Yiqi Dripping Pills on Cardiovascular and Cerebrovascular Diseases and Diabetic Complications	15
Novel Chalcone BDD-39 Mitigated Diabetic Nephropathy through the Activation of Nrf2/ARE Signaling	15
Anti-Cancer Role of Dendrosomal Nano Solanine in Chronic Myelogenous Leukemia Cell Line through Attenuation of PI3K/AKT/mTOR Signaling Pathway and Inhibition of hTERT Expression	15
SK1 Inhibitor RB005 Induces Apoptosis in Colorectal Cancer Cells through SK1 Inhibition Dependent and Independent Pathway	15
Dual Role of Pregnane X Receptor in Nonalcoholic Fatty Liver Disease	15
MiR-129-2-3p Inhibits Esophageal Carcinoma Cell Proliferation, Migration, and Invasion via Targeting DNMT3B	14
The Treatment of Parkinson’s Disease with Sodium Oxybate	14
Tumor Organoid Model and Its Pharmacological Applications in Tumorigenesis Prevention	14
Molecular Insight into the Apoptotic Mechanism of Cancer Cells: An Explicative Review	14
Aloperine Alleviates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation in Macrophages and ApoE-/- Mice	14
Protective Effect of Chrysin against Chlorpyrifos-Induced Metabolic Impairment and Pancreatitis in Male Rats	14
An Essential Role of c-Fos in Notch1-mediated Promotion of Proliferation of KSHV-Infected SH-SY5Y Cells	13
Upregulation of miR-3130-5p Enhances Hepatocellular Carcinoma Growth by Suppressing Ferredoxin 1 : miR-3130-5p Enhances HCC Growth via Inhibiting FDX1	13
Water Pipe Tobacco Smoking and Risk of Coronary Artery Disease: A Systematic Review and Meta-Analysis	13
Gentiopicroside Ameliorated Ductular Reaction and Inflammatory Response in DDC-induced Murine Cholangiopathies Model	13
Natural Products and Cardiovascular Diseases	13
Sericic Acid Ameliorates DSS-induced Ulcerative Colitis in Mice by Modulating the NF-κB and Nrf2 Pathways	13
Fenbufen Alleviates Severe Acute Pancreatitis by Suppressing Caspase-1/Caspase-11-mediated Pyroptosis in Mice	12
Hypotensive Effects of the Triterpene Oleanolic Acid for Cardiovascular Prevention	12
PF-04449913 Inhibits Proliferation and Metastasis of Colorectal Cancer Cells by Down-regulating MMP9 Expression through the ERK/p65 Pathway	12
D-allose: Molecular Pathways and Therapeutic Capacity in Cancer	12
Evaluation of the Effect of Isobutyl Paraben and 2-ethyl Hexyl Paraben on P-glycoprotein Functional Expression in Rats: A Pharmacokinetic Study	11
Antinociceptive and Anti-Inflammatory Like Effects of Berberis baluchistanica	11
Thyroidectomy and PTU-Induced Hypothyroidism: Effect of L-Thyroxine on Suppression of Spatial and Non-Spatial Memory Related Signaling Molecules	11
Ergothioneine Suppresses Amyloid β-Induced Tau Phosphorylation and Cytotoxicity by Inactivating Glycogen Synthase Kinase-3β in Cultured Neurons	11
Reduction of Genotoxicity of Carbamazepine to Human Lymphocytes by Pre-treatment with Vitamin B12	11
Inhibitory Effects of Cathepsin K Inhibitor (ODN-MK-0822) on the Paracrine Pro-Osteoclast Factors of Breast Cancer Cells	11
Research Progress and Future Development Potential of Oridonin in Pharmacological Activities	10
Fenofibrate Inhibits LPS and Zymosan-induced Inflammatory Responses through Sonic Hedgehog in IMG Cells	10
Extracts from Artemisia annua Alleviates Myocardial Remodeling through TGF-β1/Smad2/3 Pathway and NLRP3 Inflammasome	10
Acknowledgements to Reviewers	10
PCSK9 Biomarker and Key Modulator for Cardiovascular Disorders: Heralding a New Therapeutic Era and Their Future Perspectives	10
Ketamine Metabolites-waiting in the Wings as Therapeutic Candidate for Depression?	10
Review of the Role of Metabolic Factors in Determining the Post-surgical Adhesion and its Therapeutic Implications, with a Focus on Extracellular Matrix and Oxidative Stress	10
Preface	10
Molecular Insights into Agonist/Antagonist Effects on Macromolecules Involved in Human Disease Mechanisms	10
Effects of Mycotoxins on Child Development	10
Gut Microbiota Modulation for Therapeutic Management of Various Diseases: A New Perspective Using Stem Cell Therapy	10
Nrf2 Mediates Effect of Resveratrol in Ischemia-reperfusion Injury	9
A Comprehensive Review of Essential Aspects of Molecular Pathophysiological Mechanisms with Emerging Interventions for Sarcopenia in Older People	9
Upregulation of LncRNA WT1-AS Inhibits Tumor Growth and Promotes Autophagy in Gastric Cancer via Suppression of PI3K/Akt/mTOR Pathway	9
RBM3 Accelerates Wound Healing of Skin in Diabetes through ERK1/2 Signaling	9

A Review on Post-traumatic Stress Disorder (PTSD): Symptoms, Therapies and Recent Case Studies	9
Retinoprotective Effects Of Crocin And Crocetin via Anti-Angiogenic Mechanism in High Glucose-Induced Human Retinal Pigment Epithelium Cells	8
Influence of SGLT2 Inhibitors in Remodeling, Substrate and Ion Metabolism of Myocardium to Prevent Cardiovascular Risks: Recent Work and Advancement	8
Sanguinarine Attenuates Lung Cancer Progression via Oxidative Stress-induced Cell Apoptosis	8
Disruption of Wnt/β-catenin Pathway Elevates the Sensitivity of Gastric Cancer Cells to PD-1 Antibody	8
Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics	8
Maprotiline Prompts an Antitumour Effect by Inhibiting PD-L1 Expression in Mice with Melanoma	8
TRIM65 in White Matter Lesions, Innate Immunity, and Tumor	8
L-theanine inhibits mammalian target of rapamycin-p70S6K pathway-mediated neuroexcitation induced by N-methyl-D-aspartate	8
Neuroprotective Effects of Shogaol in Metals (Al, As and Pb) and High-fat diet-induced Neuroinflammation and Behavior in Mice	8
Short-term Uridine Treatment Alleviates Endoplasmic Reticulum Stress via Regulating Inflammation and Oxidative Stress in Lithium-Pilocarpine Model of Status Epilepticus	8
Potential Therapeutic Strategies to Combat HCC	8
Current Strategies for the Management of Psoriasis with Potential Pharmacological Pathways using Herbals and Immuno-biologicals	8
Anticancer Effects of Tacrolimus on Induced Hepatocellular Carcinoma in Mice	8
Bedaquiline in Drug-Resistant Tuberculosis: A Mini-Review	8
Combined Phloretin and Human Platelet-rich Plasma Effectively Preserved Integrities of Brain Structure and Neurological Function in Rat after Traumatic Brain Damage	7
Comprehensive Analysis of SARS-COV-2 Drug Targets and Pharmacological Aspects in Treating the COVID-19	7
Epigenetic Regulation and Promising Therapies in Colorectal Cancer	7
Evaluation of Dual Inhibitory Effect of Anagliptin, Ramipril and Lisinopril on Angiotensin-Converting Enzyme and DPP-4 Activities	7
H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma	7
Depression-like Behavior Induced by Repeated Administration of Dexamethasone to Lipopolysaccharide-inflamed Mice	7
Natural Products as PI3K/ Akt Inhibitors: Implications in Preventing Hepatocellular Carcinoma	7
IDO2-siRNA Carried by Salmonella Combined with Nifuroxazide Attenuates Melanoma Growth	7
Immunomodulatory Activity of Diterpenes over Innate Immunity and Cytokine Production in a Human Alveolar Epithelial Cell Line Infected with Mycobacterium tuberculosis	7
The Regulatory Mechanism of Hypoxia-inducible Factor 1 and its Clinical Significance	7
Hepatic Ischemia-reperfusion Injury: Protective Approaches and Treatment	7
Renoprotective Effect of Thymoquinone against Streptozotocin-Induced Diabetic Nephropathy: Role of NOX2 and Nrf2 Signals	7
A Proteomics Study of the Subacute Toxicity of Rat Brain after Long- Term Exposure of Gelsemium elegans	6
At the Crossroads of TNF α Signaling and Cancer	6
Pharmacotherapy for SARS-CoV-2 and Seizures for Drug Repurposing Presumed on Mechanistic Targets	6
Thwarting Coronavirus Infections by Tapping Host Targets: The ‘Greek Gift Sacrifice’ to Curb the Menace of Drug Resistances	6
Toxicity, Genotoxicity, and Carcinogenicity of Isotretinoin	6
Neuropilin-2 Inhibits Drug Resistance and Progression of Melanoma Involving the MiR-331-3p Regulated Cascade	6
EGFR Inhibitor CL-387785 Suppresses the Progression of Lung Adenocarcinoma	6
Regulatory Mechanisms of STAT3 in GBM and its Impact on TMZ Resistance	6
Tangeretin in the Treatment of Pulmonary Fibrosis: Current Advances and Future Perspectives	6
Cilia Plays a Pivotal Role in the Hypersecretion of Airway Mucus in Mice	6
Mitochondria-targeted Uncouplers Decrease Inflammatory Reactions in Endothelial Cells by Enhancing Methylation of the ICAM1 Gene Promoter	6
The Effects of Acute and Chronic Sleep Deprivation on the Immune Profile in the Rat	6
Clozapine-induced Myocarditis: Pathophysiologic Mechanisms and Implications for Therapeutic Approaches	6
A Clinical Perspective of Soluble Epoxide Hydrolase Inhibitors in Metabolic and Related Cardiovascular Diseases	6
Immunopharmacological Properties of VitD3: 1, 25VitD3 Modulates Regulatory T Cells and Th17 Cells and the Cytokine Balance in PBMCs from Women with Unexplained Recurrent Spontaneous Abortion (URSA)	6
The Role of Complement Component 3 (C3) in Psoriasis	6
Polysaccharides to Combat Viruses (COVID-19) and Microbes: New updates	6
Anti-Diabetic Effects of Isolated Lipids from Natural Sources through Modulation of Angiogenesis	5
Network Pharmacology and Bioinformatics of Flavonoids from Scutellaria baicalensis stems: Mitigating Aβ-Induced Cognitive Impairment in Rats via the MEK-ERK-CREB Pathway	5
Bovine lactoferrin as a Modulator of Neuroendocrine Components of Stress	5
Thymoquinone Attenuates Retinal Expression of Mediators and Markers of Neurodegeneration in a Diabetic Animal Model	5
Effect of Edaravone on MicroRNA Expression in Exosomes after Hepatic Ischemia-reperfusion Injury	5
Thioacetamide-Induced Norepinephrine Production by Hepatocytes is Associated with Hepatic Stellate Cell Activation and Liver Fibrosis	5
Impact of Nicosulfuron on Sperm Quality: Insights into Testicular Cell Apoptosis and NF-κB Signaling Pathway in Mice Testes	5
Combined Bazedoxifene and Genistein Ameliorate Ovariectomy-Induced Hippocampal Neuro-Alterations via Activating CREB/BDNF/TrkB Signaling Pathway	5
Withdrawn: Variations in Altered Global Gene Expression caused by Topoisomerase II Poisons Assessed with Reference to Differences in DNA Binding	5
The Mechanistic Role of Thymoquinone in Parkinson's Disease: Focus on Neuroprotection in Pre-Clinical Studies	5
Hesperidin Exerts Anxiolytic-like Effects in Rats with Streptozotocin‐ Induced Diabetes via PKA/CREB Signaling	5
Hsa_Circ_0000021 Sponges miR-3940-3p/KPNA2 Expression to Promote Cervical Cancer Progression	5
Dual Targeting of Autophagy and NF-κB Pathway by PPARγ Contributes to the Inhibitory Effect of Demethoxycurcumin on NLRP3 Inflammasome Priming	5
Scutellarin Mediates Cytochrome P450 3A4 and 2C19 Expression via Pregnane X Receptor and Constitutive Androstane Receptor	5
Probing the Ubiquitination-Mediated Function of Epithelial Sodium Channel in A549 Cells	5
Moving Towards Dawn: KRas Signaling and Treatment in Pancreatic Ductal Adenocarcinoma	5
Chlorpyrifos with Age-Dependent Effects in Cardiac Tissue of Male Rats	5
The Struggle with Rheumatism through Dracunculus vulgaris Schott: In the Light of Ethnobotanical Information	5
Effect of Chrysin and Chrysin Nanocrystals on Chlorpyrifos-Induced Dysfunction of the Hypothalamic-Pituitary-Testicular Axis in Rats	5
Key miRNAs in Modulating Aging and Longevity: A Focus on Signaling Pathways and Cellular Targets	4
Ginkgolic Acids Confer Potential Anticancer Effects by Targeting Pro- Inflammatory and Oncogenic Signaling Molecules	4
Curcumin Efficacy in a Serum/Glucose Deprivation-Induced Neuronal PC12 Injury Model	4
The Mediating Role of miR-451/ETV4/MMP13 Signaling Axis on Epithelialmesenchymal Transition in Promoting Non-small Cell Lung Cancer Progression	4
Two GnRH-mitoxantrone Conjugates, Con-3 and Con-7, Target Endometrial Cancer Cells	4
A Detailed Review of Molecular Pathways and Mechanisms Responsible for the Development and Aggravation of Neuropathy and Nephropathy in Diabetes	4
Preventive and Therapeutic Aspects of Migraine for Patient Care: An Insight	4
The Effect of Fingolimod on Renal Ischemia/Reperfusion Injury in a Rat Model	4
Empagliflozin Mitigates High Glucose-Disrupted Mitochondrial Respiratory Function in H9c2 Cardiomyoblasts: A Comparative Study with NHE-1 and ROCK Inhibition	4
Apelin Receptor Dimerization and Oligomerization	4
Agomelatine: An Astounding Sui-generis Antidepressant?	4
Mycotoxin Exposure and Autism: A Systematic Review of the Molecular Mechanism	4
Intra-tumor DKK1 and CALML5 heterogeneity as a novel biomarker for prognosis and immunotherapy response in head and neck squamous cell carcinoma	4
PiWi RNA in Neurodevelopment and Neurodegenerative Disorders	4
Ferulic Acid Attenuates Kainate-induced Neurodegeneration in a Rat Poststatus Epilepticus Model	4
State of the Art Molecular Pharmacology, Pathogenesis and Epigenetics of 3 Major Cancers: Lung Cancer, Ovarian Cancer, and Gliomas	4
Inactivation of Parathyroid Hormone: Perspectives of Drug Discovery to Combating Hyperparathyroidism	4

Stimulation of Soluble Guanylyl Cyclase (sGC) by Cinaciguat Attenuates Sepsisinduced Cardiac Injury	4
Guggulsterone Promotes Nasopharyngeal Carcinoma Cells Exosomal Circfip1L1 to Mediate miR-125a-5p/VEGFA Affecting Tumor Angiogenesis	4
Clinical Biomarkers and Novel Drug Targets to Cut Gordian Knots of Alzheimer's Disease	4
Arsenic Exposure and Amyloid Precursor Protein Processing: A Focus on Alzheimer's Disease	4