OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cell Communication and Signaling is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-08-01 to 2023-08-01.)

Article	Citations
microRNA-141-3p-containing small extracellular vesicles derived from epithelial ovarian cancer cells promote endothelial cell angiogenesis through activating the JAK/STAT3 and NF-κB signaling pathways	67
A comprehensive pathway map of IL-18-mediated signalling	52
Lutein reverses hyperglycemia-mediated blockage of Nrf2 translocation by modulating the activation of intracellular protein kinases in retinal pigment epithelial (ARPE-19) cells	37
Fibrillin-1 and fibrillin-1-derived asprosin in adipose tissue function and metabolic disorders	30
Caught between a “Rho” and a hard place: are CCN1/CYR61 and CCN2/CTGF the arbiters of microvascular stiffness?	29
Signaling network regulating osteogenesis in mesenchymal stem cells	29
Where does the cargo go?: Solutions to provide experimental support for the “extracellular vesicle cargo transfer hypothesis”	27
HIF-hypoxia signaling in skeletal muscle physiology and fibrosis	26
A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action	25
Targeting of the tumor immune microenvironment by metformin	22
Modulation of aryl hydrocarbon receptor inhibits esophageal squamous cell carcinoma progression by repressing COX2/PGE2/STAT3 axis	20
Mechanism of inositol-requiring enzyme 1-alpha inhibition in endoplasmic reticulum stress and apoptosis in ovarian cancer cells	20
RETRACTED ARTICLE: Long non-coding RNA TP73-AS1 promotes TFAP2B-mediated proliferation, metastasis and invasion in retinoblastoma via decoying of miRNA-874-3p	19
Repurposing calcium channel blockers as antiviral drugs	18
CircRNA cPWWP2A: an emerging player in diabetes mellitus	17
Neutralizing antibody against osteopontin attenuates non-alcoholic steatohepatitis in mice	17
In silico analyses of the tumor microenvironment highlight tumoral inflammation, a Th2 cytokine shift and a mesenchymal stem cell-like phenotype in advanced in basal cell carcinomas	17
A complete map of the Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) signaling pathway	17
Berberine inhibits epithelial-mesenchymal transition and promotes apoptosis of tumour-associated fibroblast-induced colonic epithelial cells through regulation of TGF-β signalling	17
Involvement of the unfolded protein response in the protective effects of growth hormone releasing hormone antagonists in the lungs	17
Circulating Wnt1-inducible signaling pathway protein-1 (WISP-1/CCN4) is a novel biomarker of adiposity in subjects with type 2 diabetes	17
Verteporfin inhibits the persistent fibrotic phenotype of lesional scleroderma dermal fibroblasts	16
Identification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma	14
CUDC-907 enhances TRAIL-induced apoptosis through upregulation of DR5 in breast cancer cells	14
Endocannabinoid signaling pathways: beyond CB1R and CB2R	14

The CCN2/CTGF interactome: an approach to understanding the versatility of CCN2/CTGF molecular activities	13
An assembly of galanin–galanin receptor signaling network	13
GAB2 and GAB3 are expressed in a tumor stage-, grade- and histotype-dependent manner and are associated with shorter progression-free survival in ovarian cancer	12
Matrigel: history/background, uses, and future applications	12
BMP4 enhances anoikis resistance and chemoresistance of breast cancer cells through canonical BMP signaling	12
The CCN axis in cancer development and progression	12
Comprehensive transcriptomic analysis identifies novel regulators of lung adenocarcinoma	12
Gasdermin family: a promising therapeutic target for cancers and inflammation-driven diseases	12
The linkage between inflammation and fibrosis in muscular dystrophies: The axis autotaxin–lysophosphatidic acid as a new therapeutic target?	12
Photobiomodulation reduces oxidative stress in diabetic wounded fibroblast cells by inhibiting the FOXO1 signaling pathway	11
COVID-19: is fibrosis the killer?	11
Biomechanical signal communication in vascular smooth muscle cells	11
Sequence features, structure, ligand interaction, and diseases in small leucine rich repeat proteoglycans	11
DNA damage response and repair pathway modulation by non-histone protein methylation: implications in neurodegeneration	10
A network map of endothelin mediated signaling pathway	10
The role of extracellular vesicles in podocyte autophagy in kidney disease	10
CCN proteins are part of a multilayer complex system: a working model	10
Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: focus on the available therapeutic approaches and gut microbiome	9
Regulation of bone morphogenetic protein 4 on epithelial tissue	9
LRP6 mediated signal transduction pathway triggered by tissue plasminogen activator acts through lipid rafts in neuroblastoma cells	9
Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1	9
Long non-coding RNA DIO3OS/let-7d/NF-κB2 axis regulates cells proliferation and metastasis of thyroid cancer cells	9
SARS-CoV-2 signaling pathway map: A functional landscape of molecular mechanisms in COVID-19	8
The complexity of TGFβ/activin signaling in regeneration	8
Temporal VEGFA responsive genes in HUVECs: Gene signatures and potential ligands/receptors fine-tuning angiogenesis	8
A modular map of Bradykinin-mediated inflammatory signaling network	8
Cellular communication network factor 3 in cartilage development and maintenance	8
Circulating miR34a levels as a potential biomarker in the follow-up of Ewing sarcoma	8
The modulation of neuroinflammation by inducible nitric oxide synthase	8
A pathway map of AXL receptor-mediated signaling network	8
ADP exerts P2Y12 -dependent and P2Y12 -independent effects on primary human T cell responses to stimulation	7
CCN proteins in the musculoskeletal system: current understanding and challenges in physiology and pathology	7
Opioid receptors signaling network	7
Hic1 deletion unleashes quiescent connective tissue stem cells and impairs skeletal muscle regeneration	7
CSNK2B contributes to colorectal cancer cell proliferation by activating the mTOR signaling	7
Lactate regulates autophagy through ROS-mediated activation of ERK1/2/m-TOR/p-70S6K pathway in skeletal muscle	7
Comparative stemness and differentiation of luminal and basal breast cancer stem cell type under glutamine‐deprivation	7
Identification of key regulators associated with colon cancer prognosis and pathogenesis	7
YY1 regulated transcription‐based stratification of gastric tumors and identification of potential therapeutic candidates	7
CCN1 triggers adaptive autophagy in cardiomyocytes to curb its apoptotic activities	7
CCN2 (Cellular Communication Network factor 2) in the bone marrow microenvironment, normal and malignant hematopoiesis	7
A multi-cellular molecular signaling and functional network map of C–C motif chemokine ligand 18 (CCL18): a chemokine with immunosuppressive and pro-tumor functions	7
Naringenin alleviates hyperglycemia-induced renal toxicity by regulating activating transcription factor 4–C/EBP homologous protein mediated apoptosis	7
Breathe, breathe in the air: the anti-CCN2 antibody pamrevlumab (FG-3019) completes a successful phase II clinical trial for idiopathic pulmonary fibrosis	7
CD47 interactions with exportin-1 limit the targeting of m7G-modified RNAs to extracellular vesicles	7
Periostin: an emerging activator of multiple signaling pathways	7
Identification of potential key genes and miRNAs involved in Hepatoblastoma pathogenesis and prognosis	7
The network map of Elabela signaling pathway in physiological and pathological conditions	7