OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Cell Communication and Signaling is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Signaling network regulating osteogenesis in mesenchymal stem cells	40
Targeting of the tumor immune microenvironment by metformin	33
Fibrillin-1 and fibrillin-1-derived asprosin in adipose tissue function and metabolic disorders	32
A Review of Prostanoid Receptors: Expression, Characterization, Regulation, and Mechanism of Action	31
Matrigel: history/background, uses, and future applications	28
A complete map of the Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) signaling pathway	25
Verteporfin inhibits the persistent fibrotic phenotype of lesional scleroderma dermal fibroblasts	23
Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: focus on the available therapeutic approaches and gut microbiome	23
BMP4 enhances anoikis resistance and chemoresistance of breast cancer cells through canonical BMP signaling	20
Periostin: an emerging activator of multiple signaling pathways	20
Involvement of the unfolded protein response in the protective effects of growth hormone releasing hormone antagonists in the lungs	20
Repurposing calcium channel blockers as antiviral drugs	19
CircRNA cPWWP2A: an emerging player in diabetes mellitus	18
The CCN2/CTGF interactome: an approach to understanding the versatility of CCN2/CTGF molecular activities	18
Endocannabinoid signaling pathways: beyond CB1R and CB2R	17
The complexity of TGFβ/activin signaling in regeneration	16
Comprehensive transcriptomic analysis identifies novel regulators of lung adenocarcinoma	16
Sequence features, structure, ligand interaction, and diseases in small leucine rich repeat proteoglycans	15
Photobiomodulation reduces oxidative stress in diabetic wounded fibroblast cells by inhibiting the FOXO1 signaling pathway	14
The linkage between inflammation and fibrosis in muscular dystrophies: The axis autotaxin–lysophosphatidic acid as a new therapeutic target?	14
The CCN axis in cancer development and progression	14
Biomechanical signal communication in vascular smooth muscle cells	14
An assembly of galanin–galanin receptor signaling network	14
A network map of endothelin mediated signaling pathway	14
Targeting PI3K/Akt signaling in prostate cancer therapy	14

Activated fibroblasts enhance cancer cell migration by microvesicles-mediated transfer of Galectin-1	13
SARS-CoV-2 signaling pathway map: A functional landscape of molecular mechanisms in COVID-19	13
The modulation of neuroinflammation by inducible nitric oxide synthase	13
A modular map of Bradykinin-mediated inflammatory signaling network	12
COVID-19: is fibrosis the killer?	12
Lactate regulates autophagy through ROS-mediated activation of ERK1/2/m-TOR/p-70S6K pathway in skeletal muscle	12
The role of extracellular vesicles in podocyte autophagy in kidney disease	12
A pathway map of AXL receptor-mediated signaling network	12
GAB2 and GAB3 are expressed in a tumor stage-, grade- and histotype-dependent manner and are associated with shorter progression-free survival in ovarian cancer	12
YY1 regulated transcription‐based stratification of gastric tumors and identification of potential therapeutic candidates	12
tRNA-derived fragments (tRFs) in cancer	12
Skin aging from the perspective of dermal fibroblasts: the interplay between the adaptation to the extracellular matrix microenvironment and cell autonomous processes	11
Identification of key regulators associated with colon cancer prognosis and pathogenesis	11
A comprehensive network map of IL-17A signaling pathway	10
CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling	10
Long non-coding RNA DIO3OS/let-7d/NF-κB2 axis regulates cells proliferation and metastasis of thyroid cancer cells	10
Opioid receptors signaling network	10
CCN2 (Cellular Communication Network factor 2) in the bone marrow microenvironment, normal and malignant hematopoiesis	10
Chemokine signaling in cancer-stroma communications	9
CTHRC1 promotes growth, migration and invasion of trophoblasts via reciprocal Wnt/β-catenin regulation	9
CD47 interactions with exportin-1 limit the targeting of m7G-modified RNAs to extracellular vesicles	9
CSNK2B contributes to colorectal cancer cell proliferation by activating the mTOR signaling	9
The impact of cellular senescence in human adipose tissue	9
Integrin α11β1 in tumor fibrosis: more than just another cancer-associated fibroblast biomarker?	9
CCN proteins in the musculoskeletal system: current understanding and challenges in physiology and pathology	9
A network map of apelin-mediated signaling	8
A multi-cellular molecular signaling and functional network map of C–C motif chemokine ligand 18 (CCL18): a chemokine with immunosuppressive and pro-tumor functions	8
Targeting CCN2 protects against progressive non-alcoholic steatohepatitis in a preclinical model induced by high-fat feeding and type 2 diabetes	8
Naringenin alleviates hyperglycemia-induced renal toxicity by regulating activating transcription factor 4–C/EBP homologous protein mediated apoptosis	8
Cellular communication network factor 3 in cartilage development and maintenance	8
Circulating miR34a levels as a potential biomarker in the follow-up of Ewing sarcoma	8
Cellular crosstalk of glomerular endothelial cells and podocytes in diabetic kidney disease	8
Extracellular vesicles from MDA-MB-231 breast cancer cells stimulated with insulin-like growth factor 1 mediate an epithelial–mesenchymal transition process in MCF10A mammary epithelial cells	8
Identification of potential key genes and miRNAs involved in Hepatoblastoma pathogenesis and prognosis	8
The network map of Elabela signaling pathway in physiological and pathological conditions	8
Lupeol and Paclitaxel cooperate in hindering hypoxia induced vasculogenic mimicry via suppression of HIF-1α-EphA2-Laminin-5γ2 network in human oral cancer	7
Comparative stemness and differentiation of luminal and basal breast cancer stem cell type under glutamine‐deprivation	7
Novel role of long non-coding RNAs in autoimmune cutaneous disease	7
Why do humans need thrombospondin-1?	7
A review on Tsukushi: mammalian development, disorders, and therapy	7
Molecular alterations in oral cancer using high-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue	7
Calcium sensing receptor stimulates breast cancer cell migration via the Gβγ-AKT-mTORC2 signaling pathway	7
PLGF-1 contained in normal wound myofibroblast-derived microvesicles stimulated collagen production by dermal fibroblasts	6
Coronavirus: a shift in focus away from IFN response and towards other inflammatory targets	6
Temporal phosphoproteomic analysis of VEGF-A signaling in HUVECs: an insight into early signaling events associated with angiogenesis	6
The role of vascular endothelial protein tyrosine phosphatase on nitric oxide synthase function in diabetes: from molecular biology to the clinic	6
Tools used to assay genomic instability in cancers and cancer meiomitosis	6
Spermatozoa induce transcriptomic alterations in bovine oviductal epithelial cells prior to initial contact	6
The cryptic role of CXCL17/CXCR8 axis in the pathogenesis of cancers: a review of the latest evidence	6
Reduced expression of Collagen 17A1 in naturally aged, photoaged, and UV-irradiated human skin in vivo: Potential links to epidermal aging	6

Prediction of cellular targets in diabetic kidney diseases with single-cell transcriptomic analysis of db/db mouse kidneys	6
A review of non-prostanoid, eicosanoid receptors: expression, characterization, regulation, and mechanism of action	6
Dysregulation of Notch-FGF signaling axis in germ cells results in cystic dilation of the rete testis in mice	6
Aneurysm severity is suppressed by deletion of CCN4	5
The functions of Ca2+/calmodulin-dependent protein kinase II (CaMKII) in diabetes progression	5
Quinacrine and Curcumin in combination decreased the breast cancer angiogenesis by modulating ABCG2 via VEGF A	5
METTL3–METTL14 complex induces necroptosis and inflammation of vascular smooth muscle cells via promoting N6 methyladenosine mRNA methylation of receptor-interacting protein 3 in abdominal aortic aneu	5
Renal tumouroids: challenges of manufacturing 3D cultures from patient derived primary cells	5
Hepatitis B virus x gene-downregulated growth-arrest specific 5 inhibits the cell viability and invasion of hepatocellular carcinoma cell lines by activating Y-box-binding protein 1/p21 signaling	5
Long non-coding RNA SOS1-IT1 promotes endometrial cancer progression by regulating hypoxia signaling pathway	5
Survival-based bioinformatics analysis to identify hub long non-coding RNAs along with lncRNA-miRNA-mRNA network for potential diagnosis/prognosis of thyroid cancer	5
Multiple G-quadruplex binding ligand induced transcriptomic map of cancer cell lines	5
The role of CCNs in controlling cellular communication in the tumor microenvironment	5
The role of nuclear factor kappa B (NF-κB) in filarial pathology	4
Slow train coming: an anti-CCN2 strategy reverses a model of chronic overuse muscle fibrosis	4
Proteome‐wide assessment of human interactome as a source of capturing domain–motif and domain‐domain interactions	4
A pathway map of signaling events triggered upon SARS-CoV infection	4
A negative feedback loop involving NF-κB/TIR8 regulates IL-1β-induced epithelial- myofibroblast transdifferentiation in human tubular cells	4
A network map of discoidin domain receptor 1(DDR1)-mediated signaling in pathological conditions	4
Novel peptide—based inhibitor for targeted inhibition of T cell function	4
Glucose-limiting conditions induce an invasive population of MDA-MB-231 breast cancer cells with increased connexin 43 expression and membrane localization	4
CCN proteins: opportunities for clinical studies—a personal perspective	4
miR-137/ERRα axis mediates chemoresistance of nasopharyngeal carcinoma cells	4
Analysis of multiple basal cell carcinomas (BCCs) arising in one individual highlights genetic tumor heterogeneity and identifies novel driver mutations	4
Chondroitin polymerizing factor predicts a poor prognosis and promotes breast cancer progression via the upstream TGF-β1/SMAD3 and JNK axis activation	4
Cooperation is the key: the CCN biological system as a gate to high complex protein superfamilies’ signaling	4
Single-cell RNA-Seq analysis of diabetic wound macrophages in STZ-induced mice	4
Advances in studies of circulating microRNAs: origination, transportation, and distal target regulation	4
METTL13 facilitates cell growth and metastasis in gastric cancer via an eEF1A/HN1L positive feedback circuit	4
SHP2 regulates adipose maintenance and adipocyte-pancreatic cancer cell crosstalk via PDHA1	3
CircRNA hsa_circ_0001627 aggravates cervical cancer progression through upregulation of FNDC3B and activating PI3K/mTOR signaling pathway	3
A molecular network map of orexin-orexin receptor signaling system	3
Transcriptional and epigenetic landscape of Ca2+-signaling genes in hepatocellular carcinoma	3
Phosphoinositide-specific phospholipase C isoforms are conveyed by osteosarcoma-derived extracellular vesicles	3
Quinacrine inhibits cMET-mediated metastasis and angiogenesis in breast cancer stem cells	3
Adipocytes reprogram prostate cancer stem cell machinery	3
Do not overwork: cellular communication network factor 3 for life in cartilage	3
Metastases from metastases: comparative metastatic potential of human cancer cell lines originated from primary tumors or metastases in various tissues	3
ROR2 promotes epithelial-mesenchymal transition by hyperactivating ERK in melanoma	3
Role of EGFR and FASN in breast cancer progression	3
Bipartite regulation of cellular communication network factor 2 and fibroblast growth factor 1 genes by fibroblast growth factor 1 through histone deacetylase 1 and fork head box protein A1	3
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling	3
Tissue distribution and transcriptional regulation of CCN5 in the heart after myocardial infarction	3