OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pharmaceutical Innovation is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Particle Size Reduction Techniques of Pharmaceutical Compounds for the Enhancement of Their Dissolution Rate and Bioavailability	46
Transdermal Delivery Systems for Biomolecules	45
A Review on Solid Microneedles for Biomedical Applications	30
Analysis of the COVID-19 Vaccine Development Process: an Exploratory Study of Accelerating Factors and Innovative Environments	26
Twin-Screw Extruder in Pharmaceutical Industry: History, Working Principle, Applications, and Marketed Products: an In-depth Review	20
Laser Enhanced Combinatorial Chemo-photothermal Therapy of Green Synthesis Gold Nanoparticles Loaded with 6Mercaptopurine on Breast Cancer Model	17
Dissolving Microneedle Formulation of Ceftriaxone: Effect of Polymer Concentrations on Characterisation and Ex Vivo Permeation Study	16
Nano Calcium Oxide Incorporated Hydrocolloid Dressings for Wound Care	15
Improving Antibacterial Efficiency of Curcumin in Magnetic Polymeric Nanocomposites	15
Systematic Development and Optimization of Teriparatide-Loaded Nanoliposomes Employing Quality by Design Approach for Osteoporosis	14
Engineering Lipase Enzyme Nano-powder Using Nano Spray Dryer BÜCHI B-90: Experimental and Factorial Design Approach for a Stable Biocatalyst Production	13
Lutein-Loaded Solid Lipid Nanoparticles for Ocular Delivery: Statistical Optimization and Ex Vivo Evaluation	13
Vesicular Formation of Trans-Ferulic Acid: an Efficient Approach to Improve the Radical Scavenging and Antimicrobial Properties	13
Hot Melt Extrusion: an Emerging Green Technique for the Synthesis of High-Quality Pharmaceutical Cocrystals	11
Development and Evaluation of Letrozole-Loaded Hyaluronic Acid/Chitosan-Coated Poly(d,l-lactide-co-glycolide) Nanoparticles	11
Development of a New Drug Delivery System from HELA-Derived Exosomes and the Effect of Docetaxel-Loaded Exosomes on Mitochondrial Apoptosis	10
A Comparative Investment Analysis of Batch Versus Continuous Pharmaceutical Manufacturing Technologies	10
Core-Shell Nanofibers Based on Polycaprolactone/Polyvinyl Alcohol and Polycaprolactone/Collagen for Biomedical Applications	9
Electrospun Poly (Vinyl Alcohol) Nanofibrous Mat Loaded with Green Propolis Extract, Chitosan and Nystatin as an Innovative Wound Dressing Material	9
Redox-Responsive and Electrically Neutral PLGA Nanoparticles for siRNA Delivery in Human Cervical Carcinoma Cells	8
Fabrication of Carboxymethylcellulose-Gelatin Dissolving Microneedle Patch for Pain-Free, Efficient, and Controlled Transdermal Delivery of Insulin	8
Alpha-Lipoic Acid and Cyanocobalamin Co-Loaded Nanoemulsions: Development, Characterization, and Evaluation of Stability	8
DoE-Based Solid Self-microemulsifying Drug Delivery System (S-SMEDDS) Approach for Improving the Dissolution Properties of Raltegravir Potassium	8
Modulating Gliclazide Release and Bioavailability Utilizing Multiparticulate Drug Delivery Systems	8
Process Design and Comparison for Batch and Continuous Manufacturing of Recombinant Adeno-Associated Virus	8

Quality-by-Design Approach for Optimization and Processing of PLGA Polymer Film by Hot Melt Extrusion	7
Mitoxantrone-Loaded PLGA Nanoparticles for Increased Sensitivity of Glioblastoma Cancer Cell to TRAIL-Induced Apoptosis	7
A Quality by Design Paradigm for Albumin-Based Nanoparticles: Formulation Optimization and Enhancement of the Antitumor Activity	7
New Approach to Formulate Methotrexate-Loaded Niosomes: In Vitro Characterization and Cellular Effectiveness	7
A Comprehensive Review of Current Perspectives on Novel Drug Delivery Systems and Approaches for Lung Cancer Management	7
The PLGA Microspheres Synthesized by a Thermosensitive Hydrogel Emulsifier for Sustained Release of Risperidone	7
Development and Pharmaceutical Evaluation of Azelaic Acid and Vitamin E Oil-Based Nanoemulgel of Tacrolimus for Topical Application in Plaque Psoriasis	7
Application of a System Model for Continuous Manufacturing of an Active Pharmaceutical Ingredient in an Industrial Environment	7
An Eco-Friendly and Hopeful Promise Platform for Delivering Hydrophilic Wound Healing Agents in Topical Administration for Wound Disorder: Diltiazem-Loaded Niosomes	7
FDA Warning Letters: A Retrospective Analysis of Letters Issued to Pharmaceutical Companies from 2010–2020	6
Development, Characterization, and Ex Vivo Permeation Assessment of Diclofenac Diethylamine Deep Eutectic Systems Across Human Skin	6
Formulation, Optimization, and Evaluation of Ultradeformable Nanovesicles for Effective Topical Delivery of Hydroquinone	6
Development, Optimization and In Vitro Characterization of Eudragit-Ganciclovir Nanosuspension or Treating Herpes Simplex Keratitis	6
Recent Advances in Dissolution Testing and Their Use to Improve In Vitro–In Vivo Correlations in Oral Drug Formulations	6
Progress on Pharmaceutical Sciences/Pharmacy Postgraduate Education: a Bibliometric Perspective	6
Development and Characterization of 5-Fluorouracil Solid Lipid Nanoparticles for Treatment of Colorectal Cancer	6
Formulation Development, Optimization by Box-Behnken Design, and In Vitro Characterization of Gefitinib Phospholipid Complex Based Nanoemulsion Drug Delivery System	6
Biopharmaceutical Industry Capability Building in India: Report from a Symposium	6
Development of Liposomal Formulation for Controlled Delivery of Valacyclovir: an In Vitro Study	6
A Comprehensive Review on Assessment and Key Control Strategies for Impurities in Drug Development with a Special Emphasis on Post-marketing Surveillance	5
Nanospanlastics as a Novel Approach for Improving the Oral Delivery of Resveratrol in Lipopolysaccharide-Induced Endotoxicity in Mice	5
Solid Lipid Nanoparticles as Carrier to Increase Local Bioavailability of Acitretin After Topical Administration in Psoriasis Treatment	5
Use of Eudragit RS PO, HPMC K100M, Ethyl Cellulose, and Their Combination for Controlling Nicorandil Release from the Bilayer Tablets with Atorvastatin as an Immediate-Release Layer	5
The Effect of Adding PVP to the Binary Solid Dispersion (Indomethacin: Kaolin) on the Formation of Physically Stable Amorphous Drug	5
Development and Evaluation of Thermoreversible Ethosomal Gel of Donepezil Hydrochloride for Intranasal Delivery	5
FDA Approaches in Monitoring Drug Quality, Forces Impacting the Drug Quality, and Recent Alternative Strategies to Assess Quality in the US Drug Supply	5
Development and In Vitro Characterization of Transferrin-Decorated Nanoemulsion Utilizing Hydrophobic Ion Pairing for Targeted Cellular Uptake	5
Design and Optimization of Novel Taste-Masked Medicated Chocolates of Dextromethorphan with In vitro and In vivo Taste Evaluation	5
Investigating the Effect of Particle Size on Cellular Uptake by Aggregation-Caused Quenching Probe–Encapsulating Solid Lipid Nanoparticles, Inhaled	5
Commercial Low Molecular Weight Heparins — Patent Ecosystem and Technology Paradigm for Quality Characterization	5
Compatibility Study Between Fenbendazole and Poly(Ethylene Oxide) with Application in Solid Dispersion Formulations Using Hot-Melt Extrusion	4
Developing and Featuring Matrix Tablets by Using Gross Linseed Mucilage as a Retardant Polymer	4
pH-Sensitive Nanoparticles Developed and Optimized Using Factorial Design for Oral Delivery of Gliclazide	4
Can Liposomes Survive Inkjet Printing? The Effect of Jetting on Key Liposome Attributes for Drug Delivery Applications	4
Encapsulation of Allopurinol in GO/CuFe2O4/IR MOF-3 Nanocomposite and In Vivo Evaluation of Its Efficiency	4
Variable Selection Based on Gray Wolf Optimization Algorithm for the Prediction of Saponin Contents in Xuesaitong Dropping Pills Using NIR Spectroscopy	4
Deep Eutectic System-Based Liquisolid Nanoparticles as Drug Delivery System of Curcumin for In-Vitro Colon Cancer Cells	4
Lutein and β-Carotene Characterization in Free and Nanodispersion Forms in Terms of Antioxidant Activity and Cytotoxicity	4
Formulation, Optimization, and Antioxidant Evaluation of Tetrahydrocurcumin-Loaded Ultradeformable Nanovesicular Cream	4
Preparation of Citric Acid-Locust Bean Gum (CA-LBG) for the Disintegrating Agent of Tablet Dosage Forms	4
Implementing Feedback Granule Size Control in a Continuous Dry Granulation Line Using Controlled Impeller Speed of the Granulation Unit, Compaction Force and Gap Width	4
Preparation and Evaluation of Extended-Release Nanofibers Loaded with Pramipexole as a Novel Oral Drug Delivery System: Hybridization of Hydrophilic and Hydrophobic Polymers	4
Evaluation and Monitoring of the API Content of a Portable Near Infrared Instrument Combined with Chemometrics Based on Fluidized Bed Mixing Process	4
Handsheet Coated by Polyvinyl Acetate as a Drug Release System	4
Optimization and Pharmacokinetic Study of Boswellic Acid–Loaded Chitosan-Guggul Gum Nanoparticles Using Box-Behnken Experimental Design	4
Microsponge Gel Approach to Increase the Stability and Efficacy of Avobenzone as a Sun-Protective Agent	4
Solubility and Dissolution Enhancement of Luliconazole by a Cocrystal Engineering Technique with Different Coformers	4
In Vitro Evaluation of Insulin Release from Chitosan-Alginate Macrobeads	4
Improved Anti-inflammatory Activity and Minimum Systemic Absorption from Topical Gels of Ibuprofen Formulated by Micelle or Nanoemulsion	4
Residence Time Distribution-Based Smith Predictor: an Advanced Feedback Control for Dead Time–Dominated Continuous Powder Blending Process	3

Producing High-Dose Liqui-Tablet (Ketoprofen 100 mg) for Enhanced Drug Release Using Novel Liqui-Mass Technology	3
Preparation of Novel Hard Capsule Using Water-Soluble Polysaccharides and Cellulose Nanocrystals for Drug Delivery	3
The Landscape of Neutralizing Monoclonal Antibodies (nAbs) for Treatment and Prevention of COVID-19	3
Preparation of Stable Clindamycin Phosphate Niosomes by Combination of Sorbitan Esters and their Ethoxylaed Derivatives	3
Passive Targeted Drug Delivery of Venlafaxine HCl to the Brain by Modified Chitosan Nanoparticles: Characterization, Cellular Safety Assessment, and In Vivo Evaluation	3
Polyoxyethylene Lauryl Ether (Brij-35) and Poloxamer 407–Based Non-ionic Surfactant Vesicles for Dissolution Enhancement of Tacrolimus	3
Nanostructured Lipid Carriers (NLCs) of Lumefantrine with Enhanced Permeation	3
Solidified Reverse Micellar Solution-Based Lipid Microparticles of Miconazole Nitrate: Formulation Design, Biopharmaceutical Characterization, and Dissolution Studies	3
Lipid Complex-Itraconazole in Thermosensitive Mucoadhesive Vaginal Gel to Enhance the Effectiveness of Therapy for Vulvovaginal Candidiasis: Formulation, Optimization, Characterization, and Ex vivo Ev	3
Development and Characterization of Soy Lecithin Liposome as Potential Drug Carrier Systems for Doxorubicin	3
Regulation of Generic Drugs in China: Progress and Effect of the Reform of the Review and Approval System	3
Novel Glyceryl Monostearate- and Polyethylene Glycol 6000-Based Ibuprofen Pellets Prepared by Hot-Melt Extrusion: Evaluation and Stability Assessment	3
Mucoadhesive Oro-Gel–Containing Chitosan Lipidic Nanoparticles for the Management of Oral Squamous Cell Carcinoma	3
Gossypol-Embedded Casein Nanoparticles for Potential Targeting of Ovarian Cancer: Formulation, Characterization, and Anticancer Activity	3
QbD Enabled Formulation Development of Nanoemulsion of Nimodipine for Improved Biopharmaceutical Performance	3
QBD Approach for the Design, Optimization, Development, and Characterization of Naringenin-Loaded Phytosomes to Enhance Solubility and Oral Bioavailability	3
Nanoarchitectonics: a New Horizon for Drug Targeting	3
Preparation, Optimization, and Evaluation of Dolutegravir Nanosuspension: In Vitro and In Vivo Characterization	3
Development of Paediatric Formulation of Baclofen for Improved Safety and Palatability	3
Application of the QbD Approach in the Development of a Liposomal Formulation with EGCG	3
Development and Optimization of HP-β-CD Inclusion Complex-Based Fast Orally Disintegrating Tablet of Pitavastatin Calcium	3
Development of Tamoxifen In Situ Gel Nanoemulsion for Ocular Delivery in Photoreceptor Degeneration Disorder: In Vitro Characterization, 131I-Radiolabeling, and In Vivo Biodistribution Studies	3
Preparation and Evaluation of Silver Nanoparticles Embedded in Muntingia calabura Leaf Extract to Cure White Piedra	3
Solubility Enhancement of Aripiprazole via Mesoporous Silica: Preparation, Characterization, In vitro Drug Release, and Solubility Determination	3
Influence of Nanocarrier Type on the Drug Delivery Aspects of Docetaxel: Empirical Evidences	3
Blockchain for Data Originality in Pharma Manufacturing	3
Impact of Process Parameters and Formulation Properties on Dissolution Performance of an Extended Release Tablet: a Multivariate Analysis	3
Nanosized Intranasal Delivery of Novel Self-Assembled Cubic Liquid Crystals: Formulation and Evaluation	3
Development and in Vitro/In Vivo Evaluation of Itopride Hydrochloride Expanding Tablets	3
Formulation Development of Dual Drug-Loaded Thermosensitive Ocular In Situ Gel Using Factorial Design	3