OOIR: Observatory of International Research

Papers

(The TQCC of New Biotechnology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-01-01 to 2025-01-01.)

Article	Citations
Improving CRISPR-Cas9 mediated genome integration in interspecific hybrid yeasts	244
Bioinformatics based discovery of new keratinases in protease family M36	169
An artificial intelligence approach for identification of microalgae cultures	169
Streamlined life cycle assessment of single use technologies in biopharmaceutical manufacture	136
A Roadmap for Industry to Harness Biotechnology for a More Circular Economy	77
Porcine circovirus 2 capsid protein produced in N. benthamiana forms virus-like particles that elicit production of virus-neutralizing antibodies in guinea pigs	76
Combinatorial mutagenesis with alternative CDR-L1 and -H2 loop lengths contributes to affinity maturation of antibodies	69
Towards a bioeconomic vision for New Zealand – Unlocking barriers to enable new pathways and trajectories	49
A unique class I polyhydroxyalkanoate synthase (PhaC) from Brevundimonas sp. KH11J01 exists as a functional trimer: A comparative study with PhaC from Cupriavidus necator H16	47
Combining the mechanical ball milling of the carbohydrate and the use of low solvent reaction media for the synthesis of fructose fatty acid esters by immobilized lipases	44
Eliminating OFF-frame clones in randomized gene libraries: An improved split β-lactamase enrichment system	41
Editorial Board	39
Microfluidic tool for rapid functional characterization of CRISPR complexes	38
Improving 3-hydroxypropionic acid production in E. coli by in silico prediction of new metabolic targets	38
Controlled co-immobilisation of proteins via 4′-phosphopantetheine-mediated site-selective covalent linkage	36
Editorial Board	35
Continuous H-B-E fermentation by Clostridium carboxidivorans: CO vs syngas	34
Cell-based glycoengineering of extracellular vesicles through precise genome editing	33
Novel cis-regulatory elements as synthetic promoters to drive recombinant protein expression from the Chlamydomonas reinhardtii nuclear genome	33
Generation of an anti-idiotypic affibody-based masking domain for conditional activation of EGFR-targeting	32
A novel thermophile β-galactosidase from Thermothielavioides terrestris producing galactooligosaccharides from acid whey	29
Artificial intelligence / machine-learning tool for post-market surveillance of in vitro diagnostic assays	28
A multi-omics study to boost continuous bolaform sophorolipid production	27
Ready-to-use vertical flow paper device for instrument-free room temperature reverse transcription	27
Extracellular and intracellular phenol production by microalgae during photoautotrophic batch cultivation	23

Combination of sodium butyrate and decitabine promotes transgene expression in CHO cells via apoptosis inhibition	23
Accelerostat study in conventional and microfluidic bioreactors to assess the key role of residual glucose in the dimorphic transition of Yarrowia lipolytica in response to environmental stimuli	23
Effects of municipal waste compost on microbial biodiversity and energy production in terrestrial microbial fuel cells	22
Droplet digital PCR: A comprehensive tool for genetic analysis and prediction of bispecific antibody assembly during cell line development	22
Transcription factor-based biosensors for detection of naturally occurring phenolic acids	21
EBRC: Enhancing bioeconomy through research and communication	20
Semi-continuous cultivation of EPS-producing marine cyanobacteria: A green biotechnology to remove dissolved metals obtaining metal-organic materials	20
Poly(3-hydroxybutyrate) production from methane in bubble column bioreactors: Process simulation and design optimization	20
Bioeconomy triple factor nexus through indicator analysis	19
Split fluorescent protein-mediated multimerization of cell wall binding domain for highly sensitive and selective bacterial detection	19
Anabolism of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by Cupriavidus necator DSM 545 from spent coffee grounds oil	18
Applicability and information value of biocalorimetry for the monitoring of fungal solid-state fermentation of lignocellulosic agricultural by-products	18
Genomic mining of Geobacillus stearothermophilus GF16 for xylose production from hemicellulose-rich biomasses using secreted enzymes	18
Synthetic activation of yeast stress response improves secretion of recombinant proteins	17
Bioreactor-scale cell performance and protein production can be substantially increased by using a secretion signal that drives co-translational translocation in Pichia pastoris	17
Towards detection of SARS-CoV-2 RNA in human saliva: A paper-based cell-free toehold switch biosensor with a visual bioluminescent output	16
BIBBOX, a FAIR toolbox and App Store for life science research	16
Bioeconomy moving forward step by step – A global journey	16
CaRA – A multi-purpose phage display library for selection of calcium-regulated affinity proteins	15
3D printing: Economical and supply chain independent single-use plasticware for cell culture	15
The Jo-In protein welding system is a relevant tool to create CBM-containing plant cell wall degrading enzymes	15
When to file for a patent? The scientist's perspective	15
Renewable polymers and plastics: Performance beyond the green	14
Comparative genomics reveals the organic acid biosynthesis metabolic pathways among five lactic acid bacterial species isolated from fermented vegetables	14
Soft sensor for viable cell counting by measuring dynamic oxygen uptake rate	14
Polyhydroxyalkanoates production from cheese whey under near-seawater salinity conditions	14
Cultivation optimization promotes ginsenoside and universal triterpenoid production by engineered yeast	14
Successful combination of lactic acid bacteria and yeast fermentation and enzymatic treatment to re-cycle industrial bread by-products for bread making	14
Large-scale cultivation of Synechocystis sp. PCC6803 for the production of Poly(3-hydroxybutyrate) and its potential applications in the manufacturing of bulk and medical prototypes	13
Bioprocess intensification: Cases that (don’t) work	13
Biosynthesis of D-1,2,4-butanetriol promoted by a glucose-xylose dual metabolic channel system in engineered Escherichia coli	13
Polyethylene and related hydrocarbon polymers (“plastics”) are not biodegradable	13
The origins and success of the EFB Journal New Biotechnology under the leadership of Mike Taussig	13
TILAFeed: A bio-based inventory for circular nutrients management and achieving bioeconomy in future aquaponics	12
Variation in non-target traits in genetically modified hybrid aspens does not exceed natural variation	12
Site-directed neutralizing antibodies targeting structural sites on SARS-CoV-2 spike protein	12
ReViTA: A novel in vitro transcription system to study gene regulation	12
Approaches for high-throughput quantification of periplasmic recombinant proteins	12
Genetic code expansion in E. coli enables production of a functional ‘ready-to-click’ T cell receptor-specific scFv	11
Development of an efficient, ready to use, blood platelet-release device based on two new flow regime parameters: The periodic hydrodynamic loading and the shear stress accumulation.	11
Identification of lipolytic enzymes using high-throughput single-cell screening and sorting of a metagenomic library	11
Formation of biologically influenced palladium microstructures by Desulfovibrio desulfuricans and Desulfovibrio ferrophilus IS5	11
Phenoplate: An innovative method for assessing interacting effects of temperature and light on non-photochemical quenching in microalgae under chemical stress	11
Editorial Board	11
Rhamnolipids from non-pathogenic Acinetobacter calcoaceticus: Bioreactor-scale production, characterization and wound healing potency	11
Overexpression of Trp-related genes in Claviceps purpurea leading to increased ergot alkaloid production	11
Legal and practical challenges to authorization of gene edited plants in the EU	11
Using galactitol dehydrogenase coupled with water-forming NADH oxidase for efficient enzymatic synthesis of L-tagatose	11
Clinically compatible advances in blood-derived endothelial progenitor cell isolation and reprogramming for translational applications	10
Enzymatic synthesis of wet-resistant lignosulfonate-starch adhesives	10

A novel data-driven model for prediction and adaptive control of pH in raceway reactor for microalgae cultivation	10
Environmental evaluation of polyhydroxyalkanoates from animal slaughtering waste using Material Input Per Service Unit	10
High level production of amorphadiene using Bacillus subtilis as an optimized terpenoid cell factory	10