OOIR: Observatory of International Research

Papers

(The TQCC of New Biotechnology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
A multi-omics study to boost continuous bolaform sophorolipid production	214
Successful combination of lactic acid bacteria and yeast fermentation and enzymatic treatment to re-cycle industrial bread by-products for bread making	97
Eliminating OFF-frame clones in randomized gene libraries: An improved split β-lactamase enrichment system	59
A unique class I polyhydroxyalkanoate synthase (PhaC) from Brevundimonas sp. KH11J01 exists as a functional trimer: A comparative study with PhaC from Cupriavidus necator H16	54
3D printing: Economical and supply chain independent single-use plasticware for cell culture	46
EBRC: Enhancing bioeconomy through research and communication	45
Phenoplate: An innovative method for assessing interacting effects of temperature and light on non-photochemical quenching in microalgae under chemical stress	44
Assessing the potential of olive mill solid waste as feedstock for methane and volatile fatty acids production via anaerobic bioprocesses	44
Formation of biologically influenced palladium microstructures by Desulfovibrio desulfuricans and Desulfovibrio ferrophilus IS5	43
Is human oversight to AI systems still possible?	33
Automating the design-build-test-learn cycle towards next-generation bacterial cell factories	32
Site-directed neutralizing antibodies targeting structural sites on SARS-CoV-2 spike protein	31
Insights into the effects of anthropogenic activities on oil reservoir microbiome and metabolic potential	29
Pilot-scale production of mcl-PHA by Pseudomonas citronellolis using acetic acid as the sole carbon source	28
Modifying flavor profiles of Saccharomyces spp. for industrial brewing using FIND-IT, a non-GMO approach for metabolic engineering of yeast	28
Post-translational secretion stress regulation in Bacillus subtilis is controlled by intra- and extracellular proteases	27
Opinion: Independent third-party entities as a model for validation of commercial antibodies	26
Nucleic acid aptamers protect against lead (Pb(II)) toxicity	24
A COST Action on microbial responses to low pH: Developing links and sharing resources across the academic-industrial divide	23
Discovery of a new class of bacterial heme-containing C C cleaving oxygenases	23
Co-culture platform for tuning of cancer receptor density allows for evaluation of bispecific immune cell engagers	22
Protein coding regions prediction by fusing DNA shape features	22
Efficient surface display of single-chain variable fragments against tumor necrosis factor α on engineered probiotic Saccharomyces boulardii and its application in alleviating intestinal inflammation	21
A fattening factor to quantify the accumulation ability of microorganisms under N-starvation	19
Knock-out of the major regulator Flo8 in Komagataella phaffii results in unique host strain performance for methanol-free recombinant protein production	19

Biostimulation effect of different amendments on Cr(VI) recovering microbial community	19
Exploration and structure-based engineering of alkenal double bond reductases catalyzing the Cα Cβ double bond reduction of coniferaldehyde	19
Development of antibodies against the notch ligand Delta-Like-1 by phage display with activity against breast cancer cells	18
Establishment of an RNA-based transient expression system in the green alga Chlamydomonas reinhardtii	18
Immobilization of His6-tagged amine transaminases in microreactors using functionalized nonwoven nanofiber membranes	17
Earth: Extinguishing anthropogenic risks through harmonization	17
Fucoxanthin and docosahexaenoic acid production by cold-adapted Tisochrysis lutea	16
XPORT ENTRAP: A droplet microfluidic platform for enhanced DNA transfer between microbial species	16
Influence of feedstock source on the development of polyhydroxyalkanoates-producing mixed microbial cultures in continuously stirred tank reactors	16
Hydroxyurea selection for enhancement of homology-directed targeted integration of transgenes in CHO cells	16
Valorization of bioethanol by-products to produce unspecific peroxygenase with Agrocybe aegerita: Technological and proteomic perspectives	16
High-throughput screening for heterotrophic growth in microalgae using the Biolog Plate assay	16
A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies	16
In vivo evolution of lactic acid hyper-tolerant Clostridium thermocellum	15
In pursuit of a minimal CHO genome: Establishment of large-scale genome deletions	15
Analysis of the molecular basis for the non-amylolytic and non-proteolytic nature of Aspergillus vadensis CBS 113365	14
Improved taxadiene production by optimizing DXS expression and fusing short-chain prenyltransferases	14
An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics	14
Impact of standardization in tissue processing: the performance of different fixatives	14
Semi-continuous cultivation of EPS-producing marine cyanobacteria: A green biotechnology to remove dissolved metals obtaining metal-organic materials	13
Significance of poly(ethylene terephthalate) (PET) substrate crystallinity on enzymatic degradation	13
The Jo-In protein welding system is a relevant tool to create CBM-containing plant cell wall degrading enzymes	13
Transcription factor-based biosensors for detection of naturally occurring phenolic acids	13
Porcine circovirus 2 capsid protein produced in N. benthamiana forms virus-like particles that elicit production of virus-neutralizing antibodies in guinea pigs	13
Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness	13
Cultivation optimization promotes ginsenoside and universal triterpenoid production by engineered yeast	13
Improving 3-hydroxypropionic acid production in E. coli by in silico prediction of new metabolic targets	13
Bioinformatics based discovery of new keratinases in protease family M36	13
Soft sensor for viable cell counting by measuring dynamic oxygen uptake rate	12
Plant expression systems as an economical alternative for the production of iELISA coating antigen AHSV VP7	12
Development of an efficient, ready to use, blood platelet-release device based on two new flow regime parameters: The periodic hydrodynamic loading and the shear stress accumulation.	12
New vectors for urea-inducible recombinant protein production	12
Editorial Board	12
ReViTA: A novel in vitro transcription system to study gene regulation	12
The microalgal sector in Europe: Towards a sustainable bioeconomy	12
Targeted mutagenesis in plants using Beet curly top virus for efficient delivery of CRISPR/Cas12a components	12
Cryopreservation of plant cell cultures – Diverse practices and protocols	11
Editorial Board	11
An engineered SARS-CoV-2 receptor-binding domain produced in Pichia pastoris as a candidate vaccine antigen	11
A gradient phage-assisted continuous evolution method for screening suppressor tRNAs in Escherichia coli	11
Shedding light on the black box of a neural network used to detect prostate cancer in whole slide images by occlusion-based explainability	11
Production and characterization of novel Anti-HIV Fc-fusion proteins in plant-based systems: Nicotiana benthamiana & tobacco BY-2 cell suspension	11
The PAR promoter expression system: Modified lac promoters for controlled recombinant protein production in Escherichia coli	10
Virus inactivation using an electrically conducting virus filter in biopharmaceutical manufacturing process	10
A unique biochemical reaction pathway towards trehalulose synthesis by an amylosucrase isolated from Deinococcus deserti	10
Exploring Nordic microalgae as a potential novel source of antioxidant and bioactive compounds	10
SARS-CoV2 neutralizing activity of ozone on porous and non-porous materials	10
Phytoremediation of diclofenac using the Green Liver System: Macrophyte screening to system optimization	10
Domain shifts in dermoscopic skin cancer datasets: Evaluation of essential limitations for clinical translation	10
Bioplastic production by feeding the marine Rhodovulum sulfidophilum DSM-1374 with four different carbon sources under batch, fed-batch and semi-continuous growth regimes	10

Explainability and causability for artificial intelligence-supported medical image analysis in the context of the European In Vitro Diagnostic Regulation	10
Strategic improvement of Shewanella oneidensis for biocatalysis: Approach to media refinement and scalable application in a microbial electrochemical system	10
Open (non-sterile) cultivations of Debaryomyces hansenii for recombinant protein production combining industrial side-streams with high salt content	10
Enhancing protein productivities in CHO cells through adenosine uptake modulation – Novel insights into cellular growth and productivity regulation	10