CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease68
Meet the Editorial Board Member64
Meet the Regional Editor46
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis41
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus40
Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation33
Decoding the Inter-Relationship between Sleep Disorders and Alzheimer’s Disease Pathogenesis28
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis28
Drosophila melanogaster a Versatile Model of Parkinson’s Disease26
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives26
Restless Leg Syndrome in Patients with Liver Cirrhosis! Its Frequency, Severity, and Correlation25
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment24
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 21
Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a 21
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation21
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia20
Acute Phenobarbital Poisoning for the Management of Seizures in Newborns and Children; A Systematic Literature Review20
Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology and Cognitive Impairments19
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health18
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature18
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound18
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders18
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease18
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review17
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies17
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)17
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis17
Effectiveness and Safety Profile of Ginkgo biloba Standardized Extract (EGb761®) in Patients with Amnestic Mild Cognitive Impairment16
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease16
Vasospasm in Pediatric Subarachnoid Hemorrhage16
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis16
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care16
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways16
Neurodegenerative Diseases and Flavonoids: Special Reference to Kaempferol16
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease15
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?15
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models14
High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Accelerates onset Time of Beneficial Treating Effects and Improves Clinical Symptoms of Depression14
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus14
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine14
Autophagic Dysfunction in Dementia: Scope for Development of Potential Remedies14
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment13
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock13
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review13
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease13
Natural Products as Bioactive Agents in the Prevention of Dementia13
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review13
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial13
Hematological Consequences of Valproic Acid in Pediatric Patients: A Systematic Review with a Mechanistic Approach13
In-Silico Validation and Fabrication of Matrix Diffusion-Based Polymeric Transdermal Patches for Repurposing Gabapentin Hydrochloride in Neuropathic Pain12
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain12
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings12
Acknowledgements to Reviewers12
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders12
Obesity and Depression: Common Link and Possible Targets12
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review12
Dietary Nutrients and Prevention of Alzheimer’s Disease12
Sweroside Modulates Oxidative Stress and Neuroplasticity-Related Gene Expression in Scopolamine-Treated Zebrafish11
Arachidonic Acid Derivatives and Neuroinflammation11
Approaches for Ear-targeted Delivery Systems in Neurosensory Disorders to avoid Chronic Hearing Loss Mediated Neurological Diseases11
Carvacrol as a Potential Neuroprotective Agent for Neurological Diseases: A Systematic Review Article11
Meet the Editorial Board Member11
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology11
Emerging Treatments for Subarachnoid Hemorrhage11
The Effects and Regulatory Mechanism of Flavonoids from Stems and Leaves of Scutellaria baicalensis Georgi in Promoting Neurogenesis and Improving Memory Impairment Mediated by the BDNF-ERK-CREB Signa11
Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson’s Disease Rat Model Challenged with Rotenone11
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?11
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects11
Targeting Brain Cancer Cells by Nanorobot, a Promising Nanovehicle: New Challenges and Future Perspectives10
One-Trial Appetitive Learning Tasks for Drug Targeting10
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors10
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide10
Rethinking Catatonia: New Insights from the Autism Spectrum10
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review10
Acknowledgements to Reviewers10
Pharmacotherapy in SAH: Clinical Trial Lessons10
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders10
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series9
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO9
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases9
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review9
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females9
Benzodiazepines and Sleep Architecture: A Systematic Review9
Nanotechnological Advances in the Treatment of Epilepsy9
Lorcaserin: Worthy of Further Insights? Results from Recent Research9
Importance of Zebrafish as an Efficient Research Model for the Screening of Novel Therapeutics in Neurological Disorders9
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm9
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model8
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience8
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis8
Alzheimer Disease and Sleep Disorders: Insights into the Possible Disease Connections and the Potential Therapeutic Targets (Part II)8
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease8
Herbal Drug Interaction: Mechanistic Details through Pharmacokinetic Portfolio8
Arachidonic Acid Metabolites in Neurologic Disorders8
Meet the Editorial Board Member8
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities8
Modulation of Huntington’s Disease in Drosophila8
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders8
Neuroblastoma and Stem Cell Therapy: An Updated Review8
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment7
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia7
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders7
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers7
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease7
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria7
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease7
Melatonin Alleviates Pyroptosis of Retinal Neurons Following Acute Intraocular Hypertension7
Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report7
Preface7
Deciphering the Influence of Cigarette Smoke Carcinogens on CNS Associated Biomolecules: A Computational Synergistic Approach7
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights7
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets7
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities7
In Vivo Antidepressant Efficacy of 3-Substituted Thietane-1,1-dioxide Derivative - A Preliminary Study for Novel Anti-Depression Therapy in Neurological Disorders7
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease6
The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety6
Association between Frequency of Seizures and Number of Antiseizure Medications (ASM) in Patients with Epilepsy6
Sleep Disorders Research From 1945 to 2020: A Bibliometric Analysis6
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells6
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation6
An Overview of Acute Flaccid Myelitis6
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain6
Exploring the Various Aspects of Brain-Derived Neurotropic Factor (BDNF) in Diabetes Mellitus6
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders6
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration6
Cellular and Molecular Mechanisms of Dementia: Decoding the Causal link of Diabetes Mellitus in Alzheimer’s Disease6
Direct Modulation of the Gut Microbiota as a Therapeutic Approach for Alzheimer’s Disease6
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis6
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity6
Foresee Novel Targets for Alzheimer’s Disease by Investigating Repurposed Drugs6
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study6
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial6
Nanomedicinal Strategies as Emerging Therapeutic Avenues to Treat and Manage Cerebral Ischemia6
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms6
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