CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Meet the Editorial Board Member91
Meet the Regional Editor80
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation60
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus53
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 50
Targeting JNK3: An In-silico Approach to Uncover Potential Therapeutics for Alzheimer's Disease49
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives44
Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation34
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis34
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease33
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment29
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis29
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders27
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies26
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease26
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review26
Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota25
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature25
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound24
Insights into the Diagnosis, Treatment, and Management of Prion Diseases22
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia22
Pathological Insights into Neurodegenerative and Neurodevelopmental Disorders: Perspectives for the Development of Novel Treatment Approaches22
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health22
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis21
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?21
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis20
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease19
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus19
Vasospasm in Pediatric Subarachnoid Hemorrhage19
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care19
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways19
High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Accelerates onset Time of Beneficial Treating Effects and Improves Clinical Symptoms of Depression19
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease18
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)17
Breaking Through Barriers: The Transformative Potential of Nanomedicine in Overcoming Drug Delivery Challenges for Psychiatric Disorders17
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine16
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock16
Hematological Consequences of Valproic Acid in Pediatric Patients: A Systematic Review with a Mechanistic Approach16
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models15
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review15
Genetic Predisposition and Severity of Eating Disorders- A Review15
Impact of Structured Physical Exercise on Adolescent Depression: A Comprehensive Meta-Analysis of RCTs15
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment15
Decoding the Gut-Brain Axis in Alzheimer's Disease: Emerging Perspectives15
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings15
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease14
Obesity and Depression: Common Link and Possible Targets14
Natural Products as Bioactive Agents in the Prevention of Dementia14
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial14
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain13
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology13
Emerging Treatments for Subarachnoid Hemorrhage13
Approaches for Ear-targeted Delivery Systems in Neurosensory Disorders to avoid Chronic Hearing Loss Mediated Neurological Diseases13
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review13
The Effects and Regulatory Mechanism of Flavonoids from Stems and Leaves of Scutellaria baicalensis Georgi in Promoting Neurogenesis and Improving Memory Impairment Mediated by the BDNF-ERK-CREB Signa13
Dietary Nutrients and Prevention of Alzheimer’s Disease13
Acknowledgements to Reviewers13
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review13
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?13
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects12
Carvacrol as a Potential Neuroprotective Agent for Neurological Diseases: A Systematic Review Article12
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders12
Acknowledgements to Reviewers12
Sweroside Modulates Oxidative Stress and Neuroplasticity-Related Gene Expression in Scopolamine-Treated Zebrafish12
Arachidonic Acid Derivatives and Neuroinflammation12
Meet the Editorial Board Member11
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series11
Pharmacotherapy in SAH: Clinical Trial Lessons11
Lorcaserin: Worthy of Further Insights? Results from Recent Research11
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females11
Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson’s Disease Rat Model Challenged with Rotenone11
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors11
Nanoparticle-Based Approaches for Glioblastoma Treatment: Advances and Future Prospects11
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders11
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review11
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review11
One-Trial Appetitive Learning Tasks for Drug Targeting11
Rethinking Catatonia: New Insights from the Autism Spectrum10
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities10
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO10
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm10
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis10
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders10
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide10
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases10
Modulation of Huntington’s Disease in Drosophila10
Nanotechnological Advances in the Treatment of Epilepsy10
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience10
Benzodiazepines and Sleep Architecture: A Systematic Review10
Arachidonic Acid Metabolites in Neurologic Disorders9
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease9
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia9
Meet the Editorial Board Member9
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model9
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease9
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria9
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights9
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study8
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration8
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment8
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells8
Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function8
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets8
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers8
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial8
Neurotoxicity of Endogenous Neurotoxin Salsolinol in Parkinson's Disease8
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders8
Preface8
In Vivo Antidepressant Efficacy of 3-Substituted Thietane-1,1-dioxide Derivative - A Preliminary Study for Novel Anti-Depression Therapy in Neurological Disorders8
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities8
Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report8
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation8
Parkinson’s Disease: A Progressive Neurodegenerative Disorder and Structure-Activity Relationship of MAO Inhibitor Scaffolds as an Important Therapeutic Regimen8
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease8
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease7
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis7
An Overview of Acute Flaccid Myelitis7
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders7
Role of Lipocalin-2 in N1/N2 Neutrophil Polarization After Stroke7
The Protective Effects of Pioglitazone Against Cognitive Impairment Caused by L-methionine Administration in a Rat Model7
How Do Abnormalities in the Cerebrospinal Fluid Impact Neuropsychology with Progressing Age?7
Abnormality of Voltage-Gated Sodium Channels in Disease Development of the Nervous System. A Review Article7
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity7
Foresee Novel Targets for Alzheimer’s Disease by Investigating Repurposed Drugs7
Direct Modulation of the Gut Microbiota as a Therapeutic Approach for Alzheimer’s Disease7
Meet the Editorial Board Member7
Ferroptosis Targeting Offers a Therapeutic Strategy for Subarachnoid Hemorrhage7
Structural Activity Relationship based Medicinal Perspectives of Pyrimidine Derivatives as Anti-Alzheimer’s Agents: A Comprehensive Review7
The Possible Protective Effect of Taurine on Bisphenol Induced Structural Changes on the Cerebral Cortex of Rats: Histological and Immunohistochemical Study7
Role of Imaging Genetics in Alzheimer’s Disease: A Systematic Review and Current Update7
The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety7
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms7
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain7
Association between Frequency of Seizures and Number of Antiseizure Medications (ASM) in Patients with Epilepsy7
Pre-clinical Aspects and Contemporary Treatments of Parkinson’s Disease7
A Causal-Pathway Phenotype of Chronic Fatigue Syndrome due to Hemodialysis in Patients with End-Stage Renal Disease7
Neural Basis of Dental Pulp Stem Cells and its Potential Application in Parkinson’s Disease7
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