CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Meet the Editorial Board Member117
Meet the Regional Editor77
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation66
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis61
Breaking Barriers: Advanced Pharmacological Mediators for Neuropsychiatric Disorders61
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease39
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 38
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus36
Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation36
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives36
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis33
Targeting JNK3: An In-silico Approach to Uncover Potential Therapeutics for Alzheimer’s Disease33
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment30
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies30
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease30
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review29
Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota29
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia26
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders25
Microbiota-Gut-Brain Axis: A Novel Paradigm in the Neurobiology of Anxiety24
From Microbes to Minds: The Impact of Gut Bacteria on Infant Cognitive Growth24
Pathological Insights into Neurodegenerative and Neurodevelopmental Disorders: Perspectives for the Development of Novel Treatment Approaches24
Precision Neurodegeneration: Integrating Molecular Mechanisms, Biomarkers, and Targeted Therapeutics22
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health21
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature20
AI-Driven Biomarker Discovery in Motor-Related Neurodegenerative Diseases20
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?20
Insights into the Diagnosis, Treatment, and Management of Prion Diseases20
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound20
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis20
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis19
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease19
Breaking Through Barriers: The Transformative Potential of Nanomedicine in Overcoming Drug Delivery Challenges for Psychiatric Disorders19
Vasospasm in Pediatric Subarachnoid Hemorrhage18
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease18
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus18
Black phosphorus in neurological disorders: Current therapeutic applications, mechanisms, and future prospects18
Nanoformulations: A Progressive Strategy for Alleviating Migraine through Nasal Route17
Solid Lipid Nanoparticle Mediated Intranasal Drug Delivery for Brain Targeting: A Comprehensive Review17
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care17
IL-33 is Required for Behavioral Deficits in a Murine Model of Systemic Lupus Erythematosus Through Regulation of Microglia Glycolysis17
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways17
High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Accelerates onset Time of Beneficial Treating Effects and Improves Clinical Symptoms of Depression17
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)16
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine15
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models15
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment15
Genetic Predisposition and Severity of Eating Disorders- A Review14
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock14
Natural Products as Bioactive Agents in the Prevention of Dementia14
Impact of Structured Physical Exercise on Adolescent Depression: A Comprehensive Meta-Analysis of RCTs14
Epilepsy: Modern Treatment Approaches, Clinical Aspects, and Patent Status14
Decoding the Gut-Brain Axis in Alzheimer's Disease: Emerging Perspectives14
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial14
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review14
Transcription Factor Pet-1/FEV as a Potential Therapeutic Target in Anxiety and Depressive Disorders13
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings13
Acknowledgements to Reviewers13
Targeting Blood-Brain Barrier Damage with Nanotechnology in the Fight Against Neurodegenerative Diseases13
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review13
Fisetin and Neurodegeneration: From Preclinical Studies to Potential Clinical Applications13
Obesity and Depression: Common Link and Possible Targets13
Effect of Dual-task Exercise on Cognition and Dual-task Cost in the Elderly with Mild Cognitive Impairment: A Randomized Pilot Study13
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease13
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain13
Sweroside Modulates Oxidative Stress and Neuroplasticity-Related Gene Expression in Scopolamine-Treated Zebrafish12
Effects of Hesperetin Early Intervention on Brain Neurons and Microglia in APPswe/PS1dE9 Mice12
Emerging Treatments for Subarachnoid Hemorrhage12
Mechanism of Glioblastoma Treatment Targeting Growth Factors: IGF-I Case Using Gene, Immune, Phytochemicals, and Nanotechnologies12
Approaches for Ear-targeted Delivery Systems in Neurosensory Disorders to avoid Chronic Hearing Loss Mediated Neurological Diseases12
The Effect of a Novel Antibody-based Drug, Prospekta, on Brain Electrical Activity in Mice12
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders12
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology12
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?12
Tetrandrine Attenuates Cerebral Ischemia/Reperfusion Injury by Regulating Th17/Treg Balance and Mediating PI3K/Akt Pathway in Mice, Based on Network Pharmacology Analysis11
Acknowledgements to Reviewers11
Pharmacotherapy in SAH: Clinical Trial Lessons11
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects11
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders11
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors11
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review11
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series11
Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson’s Disease Rat Model Challenged with Rotenone11
Insights into the Molecular Mechanisms of Neurodegenerative Diseases: Exploring Molecular Pathways and the Therapeutic Potential of Rivastigmine10
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review10
Focused Ultrasound-activated Extracellular Vesicles–nanoparticle Hybrids for Targeted Brain Drug Delivery: Engineering Strategies and Translational Outlook10
Cannabidiol in Epilepsy: Restoring Locomotion and Seizure Control10
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO10
Rethinking Catatonia: New Insights from the Autism Spectrum10
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females10
One-Trial Appetitive Learning Tasks for Drug Targeting10
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review10
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases10
Lorcaserin: Worthy of Further Insights? Results from Recent Research10
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model9
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia9
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease9
Benzodiazepines and Sleep Architecture: A Systematic Review9
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm9
Challenges in Brain Drug Delivery for Neurodegenerative Disorders and Recent Trends: A Review9
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities9
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets9
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria9
Nanoparticle-Based Approaches for Glioblastoma Treatment: Advances and Future Prospects9
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience9
Nanotechnological Advances in the Treatment of Epilepsy9
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders9
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights9
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease9
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide9
Therapeutic Potential of Nutritional Modulators in Traumatic Brain Injury: A Systematic Review9
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis9
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers8
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration8
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation8
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial8
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders8
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease8
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment8
Preface8
Neurotoxicity of Endogenous Neurotoxin Salsolinol in Parkinson's Disease8
Bibliometric Analysis of Neutrophil Extracellular Traps in Stroke: Research Trends and Hotspots8
Synergistic Roles of Neuropeptide S and Environmental Enrichment in Preclinical Huntington’s Disease Depression Models7
An Overview of Acute Flaccid Myelitis7
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders7
Parkinson’s Disease: A Progressive Neurodegenerative Disorder and Structure-Activity Relationship of MAO Inhibitor Scaffolds as an Important Therapeutic Regimen7
Nicotine Dependence-Induced Withdrawal Syndrome: Mechanistic Insights and Therapeutic Implications7
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study7
Cyclodextrins-Phospholipids Complex Loaded Nanofibers for Improved Oral Bioavailability and Brain Targeting for Management of Stress and Anxiety7
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms7
Integrating Synthesis, Pharmacological Activity, and Molecular Modeling to Explore 1,2,4-Triazine Fused Thiazolidin-4-one Derivatives as GABAA Receptor Modulators7
Association between Frequency of Seizures and Number of Antiseizure Medications (ASM) in Patients with Epilepsy7
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity7
Foresee Novel Targets for Alzheimer’s Disease by Investigating Repurposed Drugs7
Targeting Vascular Dementia: Pharmacological Mechanisms and Therapeutic Strategies7
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells7
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities7
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain7
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis7
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease7
Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function7
The Role of the cGAS-STING Pathway in Central Nervous System Diseases7
Protective Effects of Memantine Against Acute Stress-Induced Fear Memory and Synaptic Dysfunction via NMDA Receptor Antagonism7
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