CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Meet the Editorial Board Member128
Meet the Regional Editor86
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation72
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis68
Breaking Barriers: Advanced Pharmacological Mediators for Neuropsychiatric Disorders66
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 41
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives40
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus40
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis39
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment38
Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation37
Targeting JNK3: An In-silico Approach to Uncover Potential Therapeutics for Alzheimer’s Disease33
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease31
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review30
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies30
Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota29
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia29
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders28
From Microbes to Minds: The Impact of Gut Bacteria on Infant Cognitive Growth26
AI-Driven Biomarker Discovery in Motor-Related Neurodegenerative Diseases25
Precision Neurodegeneration: Integrating Molecular Mechanisms, Biomarkers, and Targeted Therapeutics25
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease24
Insights into the Diagnosis, Treatment, and Management of Prion Diseases24
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis24
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature23
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound22
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?20
Microbiota-Gut-Brain Axis: A Novel Paradigm in the Neurobiology of Anxiety20
Breaking Through Barriers: The Transformative Potential of Nanomedicine in Overcoming Drug Delivery Challenges for Psychiatric Disorders20
Pathological Insights into Neurodegenerative and Neurodevelopmental Disorders: Perspectives for the Development of Novel Treatment Approaches20
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis20
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health20
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease19
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease19
Black phosphorus in neurological disorders: Current therapeutic applications, mechanisms, and future prospects18
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus18
IL-33 is Required for Behavioral Deficits in a Murine Model of Systemic Lupus Erythematosus Through Regulation of Microglia Glycolysis18
Modulating the Microbiota-gut-brain Axis: A Promising Strategy for Alzheimer’s Disease Prevention and Management17
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care17
Nanoformulations: A Progressive Strategy for Alleviating Migraine through Nasal Route17
Solid Lipid Nanoparticle Mediated Intranasal Drug Delivery for Brain Targeting: A Comprehensive Review17
Vasospasm in Pediatric Subarachnoid Hemorrhage17
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)17
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models16
Endothelial-to-mesenchymal Transition at the Blood–brain Barrier: Molecular Mechanisms and Pathological Roles Across Brain Diseases16
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment16
Genetic Predisposition and Severity of Eating Disorders- A Review16
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine16
Epilepsy: Modern Treatment Approaches, Clinical Aspects, and Patent Status15
Targeting Blood-Brain Barrier Damage with Nanotechnology in the Fight Against Neurodegenerative Diseases15
Obesity and Depression: Common Link and Possible Targets15
Fisetin and Neurodegeneration: From Preclinical Studies to Potential Clinical Applications15
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review15
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock15
Impact of Structured Physical Exercise on Adolescent Depression: A Comprehensive Meta-Analysis of RCTs15
Natural Products as Bioactive Agents in the Prevention of Dementia14
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease14
Effect of Dual-task Exercise on Cognition and Dual-task Cost in the Elderly with Mild Cognitive Impairment: A Randomized Pilot Study14
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings14
Decoding the Gut-Brain Axis in Alzheimer's Disease: Emerging Perspectives14
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review14
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial14
Role of Cholesterol Metabolism in the Link Between Diabetes and Alzheimer's Disease14
Transcription Factor Pet-1/FEV as a Potential Therapeutic Target in Anxiety and Depressive Disorders14
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review13
Sweroside Modulates Oxidative Stress and Neuroplasticity-Related Gene Expression in Scopolamine-Treated Zebrafish13
Effects of Hesperetin Early Intervention on Brain Neurons and Microglia in APPswe/PS1dE9 Mice13
The Effect of a Novel Antibody-based Drug, Prospekta, on Brain Electrical Activity in Mice13
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?13
Acknowledgements to Reviewers13
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology13
Mechanism of Glioblastoma Treatment Targeting Growth Factors: IGF-I Case Using Gene, Immune, Phytochemicals, and Nanotechnologies12
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain12
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders12
Emerging Treatments for Subarachnoid Hemorrhage12
Tetrandrine Attenuates Cerebral Ischemia/Reperfusion Injury by Regulating Th17/Treg Balance and Mediating PI3K/Akt Pathway in Mice, Based on Network Pharmacology Analysis12
Acknowledgements to Reviewers11
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders11
Insights into the Molecular Mechanisms of Neurodegenerative Diseases: Exploring Molecular Pathways and the Therapeutic Potential of Rivastigmine11
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects11
Focused Ultrasound-activated Extracellular Vesicles–nanoparticle Hybrids for Targeted Brain Drug Delivery: Engineering Strategies and Translational Outlook11
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors11
Pharmacotherapy in SAH: Clinical Trial Lessons11
Exosomes in Neurodegenerative Disorders: Isolation Strategies, Therapeutic Potential, and Clinical Trials11
Rethinking Catatonia: New Insights from the Autism Spectrum11
One-Trial Appetitive Learning Tasks for Drug Targeting11
Cannabidiol in Epilepsy: Restoring Locomotion and Seizure Control11
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females10
Lorcaserin: Worthy of Further Insights? Results from Recent Research10
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review10
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO10
Nanoparticle-Based Approaches for Glioblastoma Treatment: Advances and Future Prospects10
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review10
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases10
Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson’s Disease Rat Model Challenged with Rotenone10
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series10
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide10
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience9
Nanotechnological Advances in the Treatment of Epilepsy9
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm9
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment9
Challenges in Brain Drug Delivery for Neurodegenerative Disorders and Recent Trends: A Review9
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model9
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities9
Therapeutic Potential of Nutritional Modulators in Traumatic Brain Injury: A Systematic Review9
Linking Neurodegeneration and Age-related Macular Degeneration: Unified Pathways and Intervention Strategies9
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria9
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights9
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets9
Benzodiazepines and Sleep Architecture: A Systematic Review9
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis9
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders9
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease9
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia9
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease9
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial8
Neurotoxicity of Endogenous Neurotoxin Salsolinol in Parkinson's Disease8
Protective Effects of Memantine Against Acute Stress-Induced Fear Memory and Synaptic Dysfunction via NMDA Receptor Antagonism8
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration8
Preface8
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities8
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers8
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders8
Nicotine Dependence-Induced Withdrawal Syndrome: Mechanistic Insights and Therapeutic Implications8
Bibliometric Analysis of Neutrophil Extracellular Traps in Stroke: Research Trends and Hotspots8
Foresee Novel Targets for Alzheimer’s Disease by Investigating Repurposed Drugs7
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells7
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease7
Synergistic Roles of Neuropeptide S and Environmental Enrichment in Preclinical Huntington’s Disease Depression Models7
Association between Frequency of Seizures and Number of Antiseizure Medications (ASM) in Patients with Epilepsy7
KCNQ2 Channel as a Druggable Epilepsy Target: Advances in Pharmacological Modifiers7
An Overview of Acute Flaccid Myelitis7
Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function7
Cyclodextrins-Phospholipids Complex Loaded Nanofibers for Improved Oral Bioavailability and Brain Targeting for Management of Stress and Anxiety7
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study7
Integrating Synthesis, Pharmacological Activity, and Molecular Modeling to Explore 1,2,4-Triazine Fused Thiazolidin-4-one Derivatives as GABAA Receptor Modulators7
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders7
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity7
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis7
Targeting Vascular Dementia: Pharmacological Mechanisms and Therapeutic Strategies7
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation7
The Role of Helicobacter pylori CagA Protein in Inhibiting Amyloid Protein Aggregation7
The Role of the cGAS-STING Pathway in Central Nervous System Diseases7
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain7
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease7
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms7
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