CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Meet the Editorial Board Member70
Meet the Regional Editor65
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis47
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus43
Decoding the Inter-Relationship between Sleep Disorders and Alzheimer’s Disease Pathogenesis40
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives37
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 31
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation30
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis29
Restless Leg Syndrome in Patients with Liver Cirrhosis! Its Frequency, Severity, and Correlation27
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment26
Drosophila melanogaster a Versatile Model of Parkinson’s Disease25
Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a 22
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders21
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease21
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature20
Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota20
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease20
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies20
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound20
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review19
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia19
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis19
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health18
Vasospasm in Pediatric Subarachnoid Hemorrhage18
Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology and Cognitive Impairments18
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease18
High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Accelerates onset Time of Beneficial Treating Effects and Improves Clinical Symptoms of Depression18
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis17
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus17
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways17
Effectiveness and Safety Profile of Ginkgo biloba Standardized Extract (EGb761®) in Patients with Amnestic Mild Cognitive Impairment17
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease16
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?16
Neurodegenerative Diseases and Flavonoids: Special Reference to Kaempferol16
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)15
Autophagic Dysfunction in Dementia: Scope for Development of Potential Remedies15
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care15
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review14
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine14
Hematological Consequences of Valproic Acid in Pediatric Patients: A Systematic Review with a Mechanistic Approach14
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease14
Natural Products as Bioactive Agents in the Prevention of Dementia14
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment14
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review13
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock13
Dietary Nutrients and Prevention of Alzheimer’s Disease13
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models13
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings13
In-Silico Validation and Fabrication of Matrix Diffusion-Based Polymeric Transdermal Patches for Repurposing Gabapentin Hydrochloride in Neuropathic Pain13
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial13
Obesity and Depression: Common Link and Possible Targets13
Acknowledgements to Reviewers13
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects12
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review12
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders12
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?12
Approaches for Ear-targeted Delivery Systems in Neurosensory Disorders to avoid Chronic Hearing Loss Mediated Neurological Diseases12
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology12
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain12
Arachidonic Acid Derivatives and Neuroinflammation11
Sweroside Modulates Oxidative Stress and Neuroplasticity-Related Gene Expression in Scopolamine-Treated Zebrafish11
Acknowledgements to Reviewers11
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females11
The Effects and Regulatory Mechanism of Flavonoids from Stems and Leaves of Scutellaria baicalensis Georgi in Promoting Neurogenesis and Improving Memory Impairment Mediated by the BDNF-ERK-CREB Signa11
Meet the Editorial Board Member11
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors11
Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson’s Disease Rat Model Challenged with Rotenone11
Carvacrol as a Potential Neuroprotective Agent for Neurological Diseases: A Systematic Review Article11
Emerging Treatments for Subarachnoid Hemorrhage11
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders11
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO10
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review10
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review10
One-Trial Appetitive Learning Tasks for Drug Targeting10
Pharmacotherapy in SAH: Clinical Trial Lessons10
Lorcaserin: Worthy of Further Insights? Results from Recent Research10
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide10
Targeting Brain Cancer Cells by Nanorobot, a Promising Nanovehicle: New Challenges and Future Perspectives10
Nanotechnological Advances in the Treatment of Epilepsy9
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm9
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis9
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series9
Herbal Drug Interaction: Mechanistic Details through Pharmacokinetic Portfolio9
Modulation of Huntington’s Disease in Drosophila9
Rethinking Catatonia: New Insights from the Autism Spectrum9
Benzodiazepines and Sleep Architecture: A Systematic Review9
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases9
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience9
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria8
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders8
Neuroblastoma and Stem Cell Therapy: An Updated Review8
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model8
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment8
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease8
Alzheimer Disease and Sleep Disorders: Insights into the Possible Disease Connections and the Potential Therapeutic Targets (Part II)8
Deciphering the Influence of Cigarette Smoke Carcinogens on CNS Associated Biomolecules: A Computational Synergistic Approach8
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities8
Arachidonic Acid Metabolites in Neurologic Disorders8
Meet the Editorial Board Member8
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia7
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease7
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers7
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study7
In Vivo Antidepressant Efficacy of 3-Substituted Thietane-1,1-dioxide Derivative - A Preliminary Study for Novel Anti-Depression Therapy in Neurological Disorders7
Melatonin Alleviates Pyroptosis of Retinal Neurons Following Acute Intraocular Hypertension7
Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report7
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation7
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities7
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights7
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets7
Preface7
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells7
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis6
Meet the Editorial Board Member6
Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function6
Direct Modulation of the Gut Microbiota as a Therapeutic Approach for Alzheimer’s Disease6
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain6
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration6
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease6
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity6
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms6
The Possible Protective Effect of Taurine on Bisphenol Induced Structural Changes on the Cerebral Cortex of Rats: Histological and Immunohistochemical Study6
Foresee Novel Targets for Alzheimer’s Disease by Investigating Repurposed Drugs6
Parkinson’s Disease: A Progressive Neurodegenerative Disorder and Structure-Activity Relationship of MAO Inhibitor Scaffolds as an Important Therapeutic Regimen6
Sleep Disorders Research From 1945 to 2020: A Bibliometric Analysis6
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial6
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders6
Association between Frequency of Seizures and Number of Antiseizure Medications (ASM) in Patients with Epilepsy6
A Causal-Pathway Phenotype of Chronic Fatigue Syndrome due to Hemodialysis in Patients with End-Stage Renal Disease6
Role of Lipocalin-2 in N1/N2 Neutrophil Polarization After Stroke6
An Overview of Acute Flaccid Myelitis6
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease6
The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety6
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders6
Cellular and Molecular Mechanisms of Dementia: Decoding the Causal link of Diabetes Mellitus in Alzheimer’s Disease6
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