CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Meet the Editorial Board Member75
Meet the Regional Editor68
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus51
Decoding the Inter-Relationship between Sleep Disorders and Alzheimer’s Disease Pathogenesis44
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 44
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation43
Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation36
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis34
Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a 32
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment28
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis28
Restless Leg Syndrome in Patients with Liver Cirrhosis! Its Frequency, Severity, and Correlation25
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease23
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives23
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review22
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders22
Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology and Cognitive Impairments22
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature21
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound21
Insights into the Diagnosis, Treatment, and Management of Prion Diseases21
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease21
Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota21
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis20
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies19
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia19
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health19
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?18
Neurodegenerative Diseases and Flavonoids: Special Reference to Kaempferol18
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease18
High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Accelerates onset Time of Beneficial Treating Effects and Improves Clinical Symptoms of Depression18
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways18
Effectiveness and Safety Profile of Ginkgo biloba Standardized Extract (EGb761®) in Patients with Amnestic Mild Cognitive Impairment17
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease17
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis17
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus17
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)16
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care16
Autophagic Dysfunction in Dementia: Scope for Development of Potential Remedies16
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine15
Natural Products as Bioactive Agents in the Prevention of Dementia15
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease15
Vasospasm in Pediatric Subarachnoid Hemorrhage15
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review15
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models14
Obesity and Depression: Common Link and Possible Targets14
Hematological Consequences of Valproic Acid in Pediatric Patients: A Systematic Review with a Mechanistic Approach14
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock14
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial14
Genetic Predisposition and Severity of Eating Disorders- A Review14
Arachidonic Acid Derivatives and Neuroinflammation13
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review13
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment13
Approaches for Ear-targeted Delivery Systems in Neurosensory Disorders to avoid Chronic Hearing Loss Mediated Neurological Diseases13
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders13
Dietary Nutrients and Prevention of Alzheimer’s Disease13
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain13
Emerging Treatments for Subarachnoid Hemorrhage13
Acknowledgements to Reviewers13
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings13
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?13
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review12
The Effects and Regulatory Mechanism of Flavonoids from Stems and Leaves of Scutellaria baicalensis Georgi in Promoting Neurogenesis and Improving Memory Impairment Mediated by the BDNF-ERK-CREB Signa12
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects12
Carvacrol as a Potential Neuroprotective Agent for Neurological Diseases: A Systematic Review Article12
Sweroside Modulates Oxidative Stress and Neuroplasticity-Related Gene Expression in Scopolamine-Treated Zebrafish12
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology12
Acknowledgements to Reviewers11
Rethinking Catatonia: New Insights from the Autism Spectrum11
Lorcaserin: Worthy of Further Insights? Results from Recent Research11
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review11
One-Trial Appetitive Learning Tasks for Drug Targeting11
Meet the Editorial Board Member11
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review11
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors10
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide10
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series10
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females10
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO10
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders10
Pharmacotherapy in SAH: Clinical Trial Lessons10
Benzodiazepines and Sleep Architecture: A Systematic Review10
Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson’s Disease Rat Model Challenged with Rotenone10
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience9
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases9
Nanotechnological Advances in the Treatment of Epilepsy9
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders9
Modulation of Huntington’s Disease in Drosophila9
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities9
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm9
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis9
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease8
Alzheimer Disease and Sleep Disorders: Insights into the Possible Disease Connections and the Potential Therapeutic Targets (Part II)8
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model8
Melatonin Alleviates Pyroptosis of Retinal Neurons Following Acute Intraocular Hypertension8
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment8
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets8
Arachidonic Acid Metabolites in Neurologic Disorders8
Meet the Editorial Board Member8
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria8
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights8
Herbal Drug Interaction: Mechanistic Details through Pharmacokinetic Portfolio8
Neuroblastoma and Stem Cell Therapy: An Updated Review8
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia8
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease8
In Vivo Antidepressant Efficacy of 3-Substituted Thietane-1,1-dioxide Derivative - A Preliminary Study for Novel Anti-Depression Therapy in Neurological Disorders8
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial7
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells7
Neurotoxicity of Endogenous Neurotoxin Salsolinol in Parkinson's Disease7
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders7
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease7
Parkinson’s Disease: A Progressive Neurodegenerative Disorder and Structure-Activity Relationship of MAO Inhibitor Scaffolds as an Important Therapeutic Regimen7
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders7
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study7
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers7
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation7
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration7
Direct Modulation of the Gut Microbiota as a Therapeutic Approach for Alzheimer’s Disease7
The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety7
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease7
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities7
Preface7
Cellular and Molecular Mechanisms of Dementia: Decoding the Causal link of Diabetes Mellitus in Alzheimer’s Disease7
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity7
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms7
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain7
Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report7
Sleep Disorders Research From 1945 to 2020: A Bibliometric Analysis7
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