Anti-Cancer Agents in Medicinal Chemistry

Article	Citations
Nitrogen-Containing Heterocycles as Anticancer Agents: An Overview	140
Reactive Oxygen Species (ROS): Key Components in Cancer Therapies	123
Schiff Bases and Complexes: A Review on Anti-Cancer Activity	71
Role of Mitochondrial Membrane Potential and Lactate Dehydrogenase A in Apoptosis	69
Molecular Mechanisms of Sanguinarine in Cancer Prevention and Treatment	41
A Review of Chemotherapy and Photodynamic Therapy for Lung Cancer Treatment	40
The Synthesis of Nano-Doxorubicin and its Anticancer Effect	38
Aromatase Inhibitors for the Treatment of Breast Cancer: A Journey from the Scratch	37
Recent Development in Indole Derivatives as Anticancer Agent: A Mechanistic Approach	36
Resveratrol as an Enhancer of Apoptosis in Cancer: A Mechanistic Review	35
A Therapeutic Journey of Pyridine-based Heterocyclic Compounds as Potent Anticancer Agents: A Review (From 2017 to 2021)	32
Recent Advances and Therapeutic Journey of Schiff Base Complexes with Selected Metals (Pt, Pd, Ag, Au) as Potent Anticancer Agents: A Review	30
Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents	28
Gallic Acid: A Dietary Polyphenol that Exhibits Anti-neoplastic Activities by Modulating Multiple Oncogenic Targets	28
Potential Impacts of Prebiotics and Probiotics on Cancer Prevention	27
Natural Products: Implication in Cancer Prevention and Treatment through Modulating Various Biological Activities	26
Recent Advancements in Organotin(IV) Complexes as Potent Cytotoxic Agents	25
Chalcone Scaffolds as Anticancer Drugs: A Review on Molecular Insight in Action of Mechanisms and Anticancer Properties	25
The Potential of Flavonoids and Tannins from Medicinal Plants as Anticancer Agents	25
Immunotherapy in Breast Cancer Patients: A Focus on the Use of the Currently Available Biomarkers in Oncology	25
Anti-Cancer Effect of Gingerol in Cancer Prevention and Treatment	25
Indazole as a Privileged Scaffold: The Derivatives and their Therapeutic Applications	24
Anticancer Activity of Selenium Nanoparticles In Vitro Studies	24
Hindering the Synchronization Between miR-486-5p and H19 lncRNA by Hesperetin Halts Breast Cancer Aggressiveness Through Tuning ICAM-1	23
Antitumor Activity of Zinc Nanoparticles Synthesized with Berberine on Human Epithelial Colorectal Adenocarcinoma (Caco-2) Cells through Acting on Cox-2/NF-kB and p53 Pathways	23

Thymoquinone Inhibits Proliferation and Migration of MDA-MB-231 Triple Negative Breast Cancer Cells by Suppressing Autophagy, Beclin-1 and LC3	23
Fused and Substituted Pyrimidine Derivatives as Profound Anti-Cancer Agents	23
Herbal Based Polymeric Nanoparticles as a Therapeutic Remedy for Breast Cancer	23
Isoquinolines: Important Cores in Many Marketed and Clinical Drugs	22
Anti-Cancer Activity of Curcumin on Multiple Myeloma	22
Factors Affecting Photodynamic Therapy and Anti-Tumor Immune Response	22
Chemoresistance in Ovarian Cancer: Prospects for New Drugs	21
Carvacrol Exhibits Chemopreventive Potential against Cervical Cancer Cells via Caspase-Dependent Apoptosis and Abrogation of Cell Cycle Progression	21
Bestowal of Quinazoline Scaffold in Anticancer Drug Discovery	21
Recent Progress in the Development of Quinoline Derivatives for the Exploitation of Anti-Cancer Agents	20
Quinoline-3-carboxylate Derivatives: A New Hope as an Antiproliferative Agent	20
Fluorinated-NHC Transition Metal Complexes: Leading Characters as Potential Anticancer Metallodrugs	20
Computational Exploration of Anti-Cancer Potential of GUAIANE Dimers from Xylopia vielana by Targeting B-Raf Kinase Using Chemo-Informatics, Molecular Docking, and MD Simulation Studies	20
Lobaplatin Induces Pyroptosis in Cervical Cancer Cells via the Caspase-3/GSDME Pathway	19
Possible Enhancement of Photodynamic Therapy (PDT) Colorectal Cancer Treatment when Combined with Cannabidiol	19
A Comprehensive Review on Journey of Pyrrole Scaffold Against Multiple Therapeutic Targets	19
Recent Advances in Metal-Organic Frameworks as Anticancer Drug Delivery Systems: A Review	19
Quality of Life Interventions in Breast Cancer Survivors: State of the Art in Targeted Rehabilitation Strategies	19
Quinoline-3-Carboxylic Acids: A Step Toward Highly Selective Antiproliferative Agent	18
Cryptolepine Targets TOP2A and Inhibits Tumor Cell Proliferation in Breast Cancer Cells -An In vitroandIn silicoStudy	18
Exploring the Molecular Mechanism of Cinnamic Acid-Mediated Cytotoxicity in Triple Negative MDA-MB-231 Breast Cancer Cells	18
Anticancer Active Heterocyclic Chalcones: Recent Developments	17
Current Insight into the Therapeutic Potential of Phytocompounds and their Nanoparticle-Based Systems for Effective Management of Lung Cancer	17
Alpha-Terpineol as Antitumor Candidate in Pre-Clinical Studies	17
Green Approaches for Cancers Management: An Effective Tool for Health Care	17
Characterization and Anticancer Activities of Green Synthesized CuO Nanoparticles, A Review	17
The Anti-Breast Cancer Effects of Green-Synthesized Zinc Oxide Nanoparticles Using Carob Extracts	16
Anti-Metastatic Effects of Lupeol via the Inhibition of MAPK/ERK Pathway in Lung Cancer	16
Advancements in the Use of Platinum Complexes as Anticancer Agents	15
Organosulphur Compounds Induce Apoptosis and Cell Cycle Arrest in Cervical Cancer Cells via Downregulation of HPV E6 and E7 Oncogenes	15
Gemini Curcumin Suppresses Proliferation of Ovarian Cancer OVCAR-3 Cells via Induction of Apoptosis	15
Prunus Armeniaca L. Seed Extract and Its Amygdalin Containing Fraction Induced Mitochondrial-Mediated Apoptosis and Autophagy in Liver Carcinogenesis	15
Alkylating Agents, the Road Less Traversed, Changing Anticancer Therapy	15
Apoptosis-Inducing Activity and Antiproliferative Effect of Gossypin on PC-3 Prostate Cancer Cells	15
Heterocyclic Compounds: Importance in Anticancer Drug Discovery	15
Periplogenin Activates ROS-ER Stress Pathway to Trigger Apoptosis via BIP-eIF2α- CHOP and IRE1α-ASK1-JNK Signaling Routes	15
Panax notoginseng Saponins Promote Cell Death and Chemosensitivity in Pancreatic Cancer through the Apoptosis and Autophagy Pathways	14
A Mini-Review on Nano Technology in the Tumour Targeting Strategies: Drug Delivery to Cancer Cells	14
Role of Collagen Regulators in Cancer Treatment: A Comprehensive Review	14
Ruxolitinib Regulates the Autophagy Machinery in Multiple Myeloma Cells	14
lncRNAs as Potential Targets in Small Cell Lung Cancer: MYC -dependent Regulation	14
Liposomal Drug Delivery and Its Potential Impact on Cancer Research	14
The Engaged Role of Tumor Microenvironment in Cancer Metabolism: Focusing on Cancer-Associated Fibroblast and Exosome Mediators	14
An Insight into Anticancer Bioactives from Punica granatum (Pomegranate)	13
Precision Oncology, Signaling, and Anticancer Agents in Cancer Therapeutics	13
Antitumor Mechanisms of Molecules Secreted by Trypanosoma cruzi in Colon and Breast Cancer: A Review	13
New Developments in Anti-Angiogenic Therapy of Cancer, Review and Update	13
Sanguinarine: A Double-Edged Sword of Anticancer and Carcinogenesis and Its Future Application Prospect	13
Lemongrass (Cymbopogon citratus (D.C.) Stapf) Presents Antitumoral Effect and Improves Chemotherapy Activity in Prostate Cancer Cells	13
Eupatilin Inhibits the Proliferation and Migration of Prostate Cancer Cells through Modulation of PTEN and NF-κB Signaling	13

Novel bis-amide-based bis-thiazoles as Anti-colorectal Cancer Agents Through Bcl-2 Inhibition: Synthesis, In Vitro, and In Vivo studies	13
Therapy Resistance in Cancers: Phenotypic, Metabolic, Epigenetic and Tumour Microenvironmental Perspectives	13
Different Methods for Cell Viability and Proliferation Assay: Essential Tools in Pharmaceutical Studies	13
Protective Effect of Isothiocyanates from Cruciferous Vegetables on Breast Cancer: Epidemiological and Preclinical Perspectives	13
Synthesis and Anti-Cancer Applications of Benzimidazole Derivatives - Recent Studies	12
Current Developments in the Pyran-Based Analogues as Anticancer Agents	12
Anti-Cancer Stem Cells Potentiality of an Anti-Malarial Agent Quinacrine: An Old Wine in a New Bottle	12
Cinobufotalin Induces Ferroptosis to Suppress Lung Cancer Cell Growth by lncRNA LINC00597/hsa-miR-367-3p/TFRC Pathway via Resibufogenin	12
Elucidation of S-Allylcysteine Role in Inducing Apoptosis by Inhibiting PD-L1 Expression in Human Lung Cancer Cells	12
Recent Advances in Epidermal Growth Factor Receptor Inhibitors (EGFRIs) and their Role in the Treatment of Cancer: A Review	12
Role of Natural and Synthetic Flavonoids as Potential Aromatase Inhibitors in Breast Cancer: Structure-Activity Relationship Perspective	12
Design, Synthesis, Molecular Docking, and Anticancer Evaluation of Pyrazole Linked Pyrazoline Derivatives with Carbothioamide Tail as EGFR Kinase Inhibitors	12
A New Series of Antileukemic Agents: Design, Synthesis, In Vitro and In Silico Evaluation of Thiazole-Based ABL1 Kinase Inhibitors	12
Nilotinib, A Tyrosine Kinase Inhibitor, Suppresses the Cell Growth and Triggers Autophagy in Papillary Thyroid Cancer	12
Synthesis of 1H-1,2,3-Triazole-Linked Quinoline-Isatin Molecular Hybrids as Anti-Breast Cancer and Anti-Methicillin-Resistant Staphylococcus aureus (MRSA) Agents	12
Design, Synthesis and Studies on Novel Polymeric Prodrugs of Erlotinib for Colon Drug Delivery	12
Anlotinib Overcomes Multiple Drug Resistant Colorectal Cancer Cells via Inactivating PI3K/AKT Pathway	12
Discovery, Development and Design of Anthocyanins-Inspired Anticancer Agents: A Comprehensive Review	12
Wogonin Induces Cell Cycle Arrest and Apoptosis of Hepatocellular Carcinoma Cells by Activating Hippo Signaling	11
The Chemosensitizing Role of Metformin in Anti-Cancer Therapy	11
Pharmaceutical Aspects of Green Synthesized Silver Nanoparticles: A Boon to Cancer Treatment	11
Anti-MDR Effects of Quercetin and its Nanoemulsion in Multidrug-Resistant Human Leukemia Cells	11
Azole-Pyrimidine Hybrid Anticancer Agents: A Review of Molecular Structure, Structure Activity Relationship, and Molecular Docking	11
Thieno[2,3-d]pyrimidin-4(3H)-one Derivatives of Benzimidazole as Potential Anti- Breast Cancer (MDA-MB-231, MCF-7) Agents	11
Induction of Apoptosis and Autophagy by Ternary Copper Complex Towards Breast Cancer Cells	11
Propolis Extract Regulates microRNA Expression in Glioblastoma and Brain Cancer Stem Cells	11
Recent Development of Copolymeric Nano-Drug Delivery System for Paclitaxel	11
Retracted: miR-27b-3p Inhibits Invasion, Migration and Epithelial-mesenchymal Transition in Gastric Cancer by Targeting RUNX1 and Activation of the Hippo Signaling Pathway	11
Evaluation of Anti-Tumor Potential of Lactobacillus acidophilus ATCC4356 Culture Supernatants in MCF-7 Breast Cancer	11
Total Synthesis, Mechanism of Action, and Antitumor Efficacy of Camptothecin and Some of its Analogues	10
Mitophagy in Carcinogenesis and Tumour Progression- A New Paradigm with Emerging Importance	10
Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents	10
Design and Development of Triazole Derivatives as Prospective Anticancer Agents: A Review	10
Drug Repurposing Strategies for Non-cancer to Cancer Therapeutics	10
Resveratrol and other Stilbenes: Effects on Dysregulated Gene Expression in Cancers and Novel Delivery Systems	10
Network-based Pharmacology and In vitro Validation Reveal that Galangin Induces Apoptosis in Bladder Cancer Cells by Promoting the P53 Signaling Pathway	10
Targeted Protein Degradation: An Emerging Therapeutic Strategy in Cancer	10
Propofol and Sevoflurane Alleviate Malignant Biological Behavior and Cisplatin Resistance of Xuanwei Lung Adenocarcinoma by Modulating the Wnt/β-catenin Pathway and PI3K/AKT Pathway	10
Recent Advances in Synthesis and Anticancer Potential of Triazole-Containing Scaffolds	10
Andrographolide Inhibits Proliferation of Colon Cancer SW-480 Cells via Downregulating Notch Signaling Pathway	10
Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines	10
Anlotinib Inhibits Cell Proliferation, Migration and Invasion via Suppression of c-Met Pathway and Activation of ERK1/2 Pathway in H446 Cells	10
Bioactive Heterocyclic Compounds as Potential Therapeutics in the Treatment of Gliomas: A Review	10
Network Pharmacology-Based and Molecular Docking Analysis of Resveratrol’s Pharmacological Effects on Type I Endometrial Cancer	10
A Focused Review on Molecular Signalling Mechanisms of Ginsenosides Anti-Lung Cancer and Anti-inflammatory Activities	9
SphK1 Promotes Cancer Progression through Activating JAK/STAT Pathway and Up-Regulating S1PR1 Expression in Colon Cancer Cells	9
Smoking is Associated with Lung Adenocarcinoma and Lung Squamous Cell Carcinoma Progression through Inducing Distinguishing lncRNA Alterations in Different Genders	9
Serum Carboxypeptidase N1 Serves as a Potential Biomarker Complementing CA15-3 for Breast Cancer	9
Molecular Mechanisms of Chloroquine and Hydroxychloroquine Used in Cancer Therapy	9
Synergistic Role of Thymoquinone on Anticancer Activity of 5-Fluorouracil in Triple Negative Breast Cancer Cells	9
Human Papillomavirus E7 Oncoprotein Promotes Proliferation and Migration through the Transcription Factor E2F1 in Cervical Cancer Cells	9
Nuciferine Inhibits Skin Cutaneous Melanoma Cell Growth by Suppressing TLR4/NF-κB Signaling	9
Mechanistic Study on Thymoquinone Conjugated ZnO Nanoparticles Mediated Cytotoxicity and Anticancer Activity in Triple-Negative Breast Cancer Cells	9
Recent Advances on Epidermal Growth Factor Receptor as a Molecular Target for Breast Cancer Therapeutics	9
Anticancer Potential of Azole Containing Marine Natural Products: Current and Future Perspectives	9
In Vitro Anticancer Evaluation of Some Synthesized 2H-Quinolinone and Halogenated 2H-Quinolinone Derivatives as Therapeutic Agents	9
Celastrol Inhibits the Proliferation and Decreases Drug Resistance of Cisplatin- Resistant Gastric Cancer SGC7901/DDP Cells	9
Dual Human Carbonic Anhydrase/Cyclooxygenase-2 Inhibitors: A Promising Approach for Cancer Treatment	9
Anti-Breast Cancer Activities of Ketoprofen-RGD Conjugate by Targeting Breast Cancer Stem-Like Cells and Parental Cells	9
The Smart Dual-Stimuli Responsive Nanoparticles for Controlled Anti-Tumor Drug Release and Cancer Therapy	9
An Appraisal on Synthetic and Medicinal Aspects of Fused Pyrimidines as Anti Neoplastic Agents	9
Identification of 3-Bromo-1-Ethyl-1H-Indole as a Potent Anticancer Agent with Promising Inhibitory Effects on GST Isozymes	9
Recombinant Human IL-11 Promotes Lung Adenocarcinoma A549 Cell Growth and EMT through Activating STAT3/HIF-1α/EMT Signaling Pathway	8
Sulphur Containing Heterocyclic Compounds as Anticancer Agents	8
Mechanisms of Cancer-killing by Quercetin; A Review on Cell Death Mechanisms	8
Natural-Derived Molecules as a Potential Adjuvant in Chemotherapy: Normal Cell Protectors and Cancer Cell Sensitizers	8
Cepharanthine Regulates Autophagy via Activating the p38 Signaling Pathway in Lung Adenocarcinoma Cells	8
The Antitumor Activity of Ginger against Colorectal Cancer Induced by Dimethylhydrazine in Rats	8
Erinacerins, Novel Glioma Inhibitors from Hericium erinaceus, Induce Apoptosis of U87 Cells through Bax/Capase-2 Pathway	8
Role of KSP Inhibitors as Anti-Cancer Therapeutics: An Update	8
Anticancer Potential of Doxorubicin in Combination with Green-Synthesized Silver Nanoparticle and its Cytotoxicity Effects on Cardio-Myoblast Normal Cells	8
Anticancer Potential of Thymoquinone: A Novel Bioactive Natural Compound from Nigella sativa L.	8
MicroRNA-520c-3p Modulates Doxorubicin-Chemosensitivity in HepG2 Cells	8
Glipizide Combined with ANP Suppresses Breast Cancer Growth and Metastasis by Inhibiting Angiogenesis through VEGF/VEGFR2 Signaling	8
Downregulation of GPR4 and TCF7 Promotes Apoptosis and Inhibits Growth and Invasion of Ovarian Cancer Cells	8
Synthesis, Aromatase Inhibitory, Antiproliferative and Molecular Modeling Studies of Functionally Diverse D-Ring Pregnenolone Pyrazoles	8
Coumarin-pyrazoline Hybrids as Selective Inhibitors of the Tumor-associated Carbonic Anhydrase IX and XII	8
Medicinal Plants for Glioblastoma Treatment	8
The Ubiquitin-Proteasome Pathway and Epigenetic Modifications in Cancer	8
Metal-based Complexes as Potential Anti-cancer Agents	8

Inhibition of Growth of Esophageal Cancer by Alantolactone via Wnt/β- Catenin Signaling	8
Recent Developments in Oxazole Derivatives as Anticancer Agents: Review on Synthetic Strategies, Mechanism of Action and SAR Studies	8
Boosting Anti-tumour Immunity Using Adjuvant Apigenin	8
The Radio-Sensitizing Effect of Pharmacological Concentration of Ascorbic Acid on Human Pancreatic Cancer Cells	8
Hyperglycemia Promotes Pancreatic Cancer Initiation and Progression by Activating the Wnt/β-Catenin Signaling Pathway	8
Novel Scopoletin Derivatives Kill Cancer Cells by Inducing Mitochondrial Depolarization and Apoptosis	8
Pistachio Green Hull Extract Induces Apoptosis through Multiple Signaling Pathways by Causing Oxidative Stress on Colon Cancer Cells	8
A Comparison of the Anti-Cancer Effects of Free and PLGA-PAA Encapsulated Hydroxytyrosol on the HT-29 Colorectal Cancer Cell Line	8
MPEG-PCL Nanomicelles Platform for Synergistic Metformin and Chrysin Delivery to Breast Cancer in Mice	8
Is It Time to Consider the Androgen Receptor as a Therapeutic Target in Breast Cancer?	8
In Vivo Biological Evaluation of Ethyl 4-(7-hydroxy-4-methyl-2-oxoquinolin-1- ylamino)-coumarin-3-carboxylate as an Antitumor Agent	8
Anti-Proliferative and Anti-Telomerase Effects of Blackberry Juice and Berry- Derived Polyphenols on HepG2 Liver Cancer Cells and Normal Human Blood Mononuclear Cells	8
Botanical Therapeutics (Part II): Antimicrobial and In Vitro Anticancer Activity against MCF7 Human Breast Cancer Cells of Chamomile, Parsley and Celery Alcoholic Extracts	8
Pulsatilla saponin A Induces Apoptosis and Differentiation of Myeloma Cells	8
Probiotics for the Chemoprotective Role against the Toxic Effect of Cancer Chemotherapy	8
Regulation of Cell Death Mechanisms by Melatonin: Implications in Cancer Therapy	7
Antimutagenic, Antiproliferative and Antioxidant Properties of Sea Grape Leaf Extract Fractions (Coccoloba uvifera L.)	7
Design, Synthesis, In Silico and In Vitro Evaluation of Novel Pyrimidine Derivatives as EGFR Inhibitors	7
Updates on Receptors Targeted by Heterocyclic Scaffolds: New Horizon in Anticancer Drug Development	7
Linc01559 Served as a Potential Oncogene and Promoted Resistance of Hepatocellular Carcinoma to Oxaliplatin by Directly Sponging miR-6783-3p	7
Erdafitinib as a Novel and Advanced Treatment Strategy of Metastatic Urothelial Carcinoma	7
Synthesis and Biological Evaluation of Coumarin Carboxamides as Selective and Potent Inhibitors of Carbonic Anhydrases IX and XII	7
Zanthoxylum bungeanum Seed Oil Elicits Autophagy and Apoptosis in Human Laryngeal Tumor Cells via PI3K/AKT/mTOR Signaling Pathway	7
Small-molecule Modulators Targeting SHP2 for Cancer Therapy	7
Improving Cytotoxicity against Breast Cancer Cells by Using Mixed-Ligand Ruthenium(II) Complexes of 2,2'-Bipyridine, Amino Acid, and Nitric Oxide Derivatives as Potential Anticancer Agents	7
Therapeutic Potential of Polyphenols and their Nanoformulations in the Treatment of Colorectal Cancer	7
One Pot Green Synthesis of Doxorubicin and Curcumin Loaded Magnetic Nanoparticles and Cytotoxicity Studies	7
Encapsulation by Electrospraying of Anticancer Compounds from Jackfruit Extract (Artocarpus heterophyllus Lam): Identification, Characterization and Antiproliferative Properties	7
Nimbolide, a Neem Limonoid, Inhibits Angiogenesis in Breast Cancer by Abrogating Aldose Reductase Mediated IGF-1/PI3K/Akt Signalling	7
Derivatives of Deoxypodophyllotoxin Induce Apoptosis through Bcl-2/Bax Proteins Expression	7
The Potential Clinical Value of Curcumin and its Derivatives in Colorectal Cancer	7
Phyto-Phospholipid Complexation as a Novel Drug Delivery System for Management of Cancer with Better Bioavailability: Current Perspectives and Future Prospects	7
A Ferrocene Derivative Reduces Cisplatin Resistance in Breast Cancer Cells through Suppression of MDR-1 Expression and Modulation of JAK2/STAT3 Signaling Pathway	7
Natural Products and Gastric Cancer: Cellular Mechanisms and Effects to Change Cancer Progression	7
Application of Selenium Nanoparticles in Localized Drug Targeting for Cancer Therapy	7
Novel Dihydropyrimidinone-Derived Selenoesters as Potential Cytotoxic Agents to Human Hepatocellular Carcinoma: Molecular Docking and DNA Fragmentation	7
Design, Synthesis, Molecular Docking, and Biological Studies of New Heterocyclic Compounds Derived from β-Diketones as Novel EGFR and Pim-1 Inhibitors Endowed with Antitumor Activity	7
MicroRNA-372-3p Predicts Response of TACE Patients Treated with Doxorubicin and Enhances Chemosensitivity in Hepatocellular Carcinoma	7
Application of Nanocellulose Derivatives as Drug Carriers; A Novel Approach in Drug Delivery	7
Chloroform Fraction of Methanolic Extract of Seeds of Annona muricata Induce S Phase Arrest and ROS Dependent Caspase Activated Mitochondria-Mediated Apoptosis in Triple-Negative Breast Cancer	7
Anti-Angiogenic and Cytotoxicity Effects of Selachyl Alcohol Analogues	7
Current Insights into the Role of BRAF Inhibitors in Treatment of Melanoma	7
Recent Insights into Therapeutic Potential of Plant-Derived Flavonoids against Cancer	7
Half-Lantern Cyclometalated Platinum(II) Complexes as Anticancer Agents: Molecular Docking, Apoptosis, Cell Cycle Analysis, and Cytotoxic Activity Evaluations	7
Phytochemical-rich Fractions from Foxtail Millet (Setaria italica (L.) P. Beauv) Seeds Exhibited Antioxidant Activity and Reduced the Viability of Breast Cancer Cells In Vitro by Inducing DNA Fragment	7
Chemical Profiling of Chlorophytum comosum (Thunb.) Jaques by GC-MS/LC-ESIMS and its Antiproliferative Effects on Human Carcinoma Cell Lines	7
Flavonoids for the Treatment of Breast Cancer, Present Status and Future Prospective	7
In-vitro Evaluation of Isatin Derivatives as Potent Anti-Breast Cancer Agents against MCF-7, MDA MB 231, MDA-MB 435 and MDA-MB 468 Breast Cancers Cell Lines: A Review	7
Identification of Natural Compounds to Inhibit Sonic Hedgehog Pathway in Oral Cancer	7
Apatinib Inhibits Stem Properties and Malignant Biological Behaviors of Breast Cancer Stem Cells by Blocking Wnt/β-catenin Signal Pathway through Downregulating LncRNA ROR	7
Preparation, Characterization and In Vitro Biological Evaluation of Novel Curcumin Derivatives as Cytotoxic and Apoptosis-Inducing Agents	7
New Synthetic Sulfonamide Chalcone Induced Cell Cycle Arrest and Cell Death in Colorectal Adenocarcinoma Metastatic Cells (SW-620)	7
A Novel 4H-Chromen-4-One Derivative from Marine Streptomyces ovatisporus S4702T as Potential Antibacterial and Anti-Cancer Agent	6
Oxidovanadium(IV) Complex Disrupts Mitochondrial Membrane Potential and Induces Apoptosis in Pancreatic Cancer Cells	6
Dehydrocostus Lactone Induces Apoptosis and Cell Cycle Arrest through Regulation of JAK2/STAT3/PLK1 Signaling Pathway in Human Esophageal Squamous Cell Carcinoma Cells	6
miRNAs Modulate the Dichotomy of Cisplatin Resistance or Sensitivity in Breast Cancer: An Update of Therapeutic Implications	6
Eryngium billardieri Extract and Fractions Induce Apoptosis in Cancerous Cells	6
Antiproliferative Activity and Apoptotic Efficiency of Syzygium cumini Bark Methanolic Extract against EAC Cells In Vivo	6
Tailored Quinolines Demonstrate Flexibility to Exert Antitumor Effects through Varied Mechanisms-A Medicinal Perspective	6
The Glutaminase Inhibitor Compound 968 Exhibits Potent In vitro and In vivo Anti-tumor Effects in Endometrial Cancer	6
Quinoline-3-Carboxylic Acids “DNA Minor Groove-Binding Agent”	6
Plant Mediated Silver Nanoparticles and Mode of Action in Cancer Therapy: A Review	6
SUV39H1-Mediated DNMT1 is Involved in the Epigenetic Regulation of Smad3 in Cervical Cancer	6
Repurposing of Alexidine Dihydrochloride as an Apoptosis Initiator and Cell Cycle Inhibitor in Human Pancreatic Cancer	6
Stimulation of Peroxisome Proliferator-Activated Receptor-Gamma (PPARγ) using Pioglitazone Decreases the Survival of Acute Promyelocytic Leukemia Cells through Up-Regulation of PTEN Expression	6
Antiglycolytic Activities of Strobilanthes crispus Active Fraction and its Bioactive Components on Triple-Negative Breast Cancer Cells In Vitro	6
Bioinformatics Analysis Predicts hsa_circ_0026337/miR-197-3p as a Potential Oncogenic ceRNA Network for Non-Small Cell Lung Cancers	6
Potential Interactions between miRNAs and Hypoxia: A New Layer in Cancer Hypoxia	6
Camphor and Menthol as Anticancer Agents: Synthesis, Structure-Activity Relationship and Interaction with Cancer Cell Lines	6
Naturally Sourced CDK Inhibitors and Current Trends in Structure-Based Synthetic Anticancer Drug Design by Crystallography	6
Carbon Nanotubes in Breast Cancer Treatment: An Insight into Properties, Functionalization, and Toxicity	6
High Diagnostic and Prognostic Value of miRNAs Compared with the Carcinoembryonic Antigen As A Traditional Tumor Marker	6
Ternary Copper (II) Complex Induced Apoptosis and Cell Cycle Arrest in Colorectal Cancer Cells	6
A Review of Anti-Cancer and Related Properties of Lichen-Extracts and Metabolites	6
Antioxidant, Anti-Inflammatory and Cytotoxic Activities of Jasminum multiflorum (Burm. F.) Andrews Leaves towards MCF-7 Breast Cancer and HCT 116 Colorectal Cell Lines and Identification of Bioactive	6
Anti-oxidant and Anticancerous Effect of Fomitopsis officinalis (Vill. ex Fr. Bond. et Sing) Mushroom on Hepatocellular Carcinoma Cells In Vitro through NF-kB Pathway	6
Single-Cell Transcriptome Analysis Reveals the M2 Macrophages and Exhausted T Cells and Intratumoral Heterogeneity in Triple-Negative Breast Cancer	6
Synthesis and Cytotoxic Properties of New Substituted Glycosides-Indole Conjugates as Apoptosis Inducers in Cancer Cells	6
Consequences of Extracellular Matrix Remodeling in Headway and Metastasis of Cancer along with Novel Immunotherapies: A Great Promise for Future Endeavor	6
Peimine Inhibits MCF-7 Breast Cancer Cell Growth by Modulating Inflammasome Activation: Critical Roles of MAPK and NF-κB Signaling	6
FOXM1-Dependent Transcriptional Regulation of EZH2 Induces Proliferation and Progression in Prostate Cancer	6
COVID-19: Our Current Knowledge of Epidemiology, Pathology, Therapeutic Approaches, and Diagnostic Methods	6
Viburnum nervosum Leaf Extract Mediated Green Synthesis of Silver Nanoparticles: A Viable Approach to Increase the Efficacy of an Anticancer Drug	6
Xanthohumol: A Metabolite with Promising Anti-Neoplastic Potential	6
Chemotherapeutic Role of Polyphenols Present in Ocimum sanctum	6
Proapoptotic Effects of triazol-1,4-Naphthoquinones Involve Intracellular ROS Production and MAPK/ERK Pathway in Human Leukemia Cells	6
The Role of 4-Thiazolidinone Scaffold in Targeting Variable Biomarkers and Pathways Involving Cancer	6
Profiling of Autophagy-Associated microRNAs in the Osteosarcoma Cell Line of U2OS	6
Anticancer Effects of Cinnamaldehyde Through Inhibition of ErbB2/HSF1/LDHA Pathway in 5637 Cell Line of Bladder Cancer	6
Molecular Docking Studies of Naringenin and its Protective Efficacy against Methotrexate Induced Oxidative Tissue Injury	6
Melittin Inhibits Growth of Human Osteosarcoma 143B Cells through Induction of Apoptosis via Suppressing the Wnt/β-catenin Signaling Pathway	6
99mTechnetium- or Cy7-Labeled Fab(Tocilizumab) as Potential Multiple Myeloma Imaging Agents	6
Construction of Biomimetic-Responsive Nanocarriers and their Applications in Tumor Targeting	6
Review of Therapies using TiO2 Nanomaterials for Increased Anticancer Capability	6
Protective Effect of Resveratrol against Glioblastoma: A Review	6