Anti-Cancer Agents in Medicinal Chemistry

Article	Citations
Nitrogen-Containing Heterocycles as Anticancer Agents: An Overview	122
Reactive Oxygen Species (ROS): Key Components in Cancer Therapies	82
Schiff Bases and Complexes: A Review on Anti-Cancer Activity	61
CDK1 in Breast Cancer: Implications for Theranostic Potential	54
Molecular Docking Studies and Inhibition Properties of Some Antineoplastic Agents against Paraoxonase-I	53
Role of Mitochondrial Membrane Potential and Lactate Dehydrogenase A in Apoptosis	50
Recent Advances of Silver Nanoparticles in Cancer Diagnosis and Treatment	49
A Review of Chemotherapy and Photodynamic Therapy for Lung Cancer Treatment	38
Evaluation of Anticancer, Antibacterial and Antioxidant Properties of a Medicinally Treasured Fern Tectaria coadunata with its Phytoconstituents Analysis by HR-LCMS	37
Quercetin-Mediated Apoptosis and Cellular Senescence in Human Colon Cancer	35
Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer	35
Apoptotic Effects of Melittin on 4T1 Breast Cancer Cell Line is associated with Up Regulation of Mfn1 and Drp1 mRNA Expression	33
Aromatase Inhibitors for the Treatment of Breast Cancer: A Journey from the Scratch	32
Resveratrol as an Enhancer of Apoptosis in Cancer: A Mechanistic Review	32
Molecular Mechanisms of Sanguinarine in Cancer Prevention and Treatment	31
The Synthesis of Nano-Doxorubicin and its Anticancer Effect	31
Dietary Phenolic Acids and Flavonoids as Potential Anti-Cancer Agents: Current State of the Art and Future Perspectives	28
Recent Development in Indole Derivatives as Anticancer Agent: A Mechanistic Approach	28
Ginsenoside Rh2 Improves the Cisplatin Anti-tumor Effect in Lung Adenocarcinoma A549 Cells via Superoxide and PD-L1	28
Current Treatment for Cervical Cancer: An Update	28
The Anticancer Properties of Silibinin: Its Molecular Mechanism and Therapeutic Effect in Breast Cancer	27
Resveratrol Counteracts Hypoxia-Induced Gastric Cancer Invasion and EMT through Hedgehog Pathway Suppression	26
Nanoformulations of Coumarins and the Hybrid Molecules of Coumarins with Potential Anticancer Effects	26
Natural Products: Implication in Cancer Prevention and Treatment through Modulating Various Biological Activities	24
Immunotherapy in Breast Cancer Patients: A Focus on the Use of the Currently Available Biomarkers in Oncology	24

Flavonoid-Based Cancer Therapy: An Updated Review	24
Computational Exploration of Anti-Cancer Potential of GUAIANE Dimers from Xylopia vielana by Targeting B-Raf Kinase Using Chemo-Informatics, Molecular Docking, and MD Simulation Studies	23
Thymoquinone Inhibits Proliferation and Migration of MDA-MB-231 Triple Negative Breast Cancer Cells by Suppressing Autophagy, Beclin-1 and LC3	23
NLRP3 Promotes Colorectal Cancer Cell Proliferation and Metastasis via Regulating Epithelial Mesenchymal Transformation	23
Gallic Acid: A Dietary Polyphenol that Exhibits Anti-neoplastic Activities by Modulating Multiple Oncogenic Targets	23
Synthesis, Anticancer, and Antibacterial Activity of Betulinic and Betulonic Acid C-28-Triphenylphosphonium Conjugates with Variable Alkyl Linker Length	22
Anticancer Effect of Amygdalin (Vitamin B-17) on Hepatocellular Carcinoma Cell Line (HepG2) in the Presence and Absence of Zinc	22
Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents	22
Anti-cancer Effects of a Neutral Triterpene Fraction from Ganoderma lucidum and its Active Constituents on SW620 Human Colorectal Cancer Cells	21
Heterocyclic Compounds Bearing Triazine Scaffold and Their Biological Significance: A Review	21
Fused and Substituted Pyrimidine Derivatives as Profound Anti-Cancer Agents	21
Chalcone Scaffolds as Anticancer Drugs: A Review on Molecular Insight in Action of Mechanisms and Anticancer Properties	21
Anti-Cancer Activity of Curcumin on Multiple Myeloma	21
Potential Impacts of Prebiotics and Probiotics on Cancer Prevention	21
Beta-Caryophyllene Suppresses Ovarian Cancer Proliferation by Inducing Cell Cycle Arrest and Apoptosis	20
A Therapeutic Journey of Pyridine-based Heterocyclic Compounds as Potent Anticancer Agents: A Review (From 2017 to 2021)	20
Herbal Based Polymeric Nanoparticles as a Therapeutic Remedy for Breast Cancer	20
Hindering the Synchronization Between miR-486-5p and H19 lncRNA by Hesperetin Halts Breast Cancer Aggressiveness Through Tuning ICAM-1	20
Bestowal of Quinazoline Scaffold in Anticancer Drug Discovery	20
Possible Enhancement of Photodynamic Therapy (PDT) Colorectal Cancer Treatment when Combined with Cannabidiol	19
Biogenic Silver and Zero-Valent Iron Nanoparticles by Feijoa: Biosynthesis, Characterization, Cytotoxic, Antibacterial and Antioxidant Activities	19
Recent Advances and Therapeutic Journey of Schiff Base Complexes with Selected Metals (Pt, Pd, Ag, Au) as Potent Anticancer Agents: A Review	19
Indazole as a Privileged Scaffold: The Derivatives and their Therapeutic Applications	19
Carvacrol Exhibits Chemopreventive Potential against Cervical Cancer Cells via Caspase-Dependent Apoptosis and Abrogation of Cell Cycle Progression	19
The Potential of Flavonoids and Tannins from Medicinal Plants as Anticancer Agents	19
Anticancer Activity of Selenium Nanoparticles In Vitro Studies	18
Quality of Life Interventions in Breast Cancer Survivors: State of the Art in Targeted Rehabilitation Strategies	18
Factors Affecting Photodynamic Therapy and Anti-Tumor Immune Response	18
Anticancer Potential of Dietary Natural Products: A Comprehensive Review	18
Fluorinated-NHC Transition Metal Complexes: Leading Characters as Potential Anticancer Metallodrugs	18
Current Insight into the Therapeutic Potential of Phytocompounds and their Nanoparticle-Based Systems for Effective Management of Lung Cancer	18
Anti-Cancer Effect of Gingerol in Cancer Prevention and Treatment	17
Cryptolepine Targets TOP2A and Inhibits Tumor Cell Proliferation in Breast Cancer Cells -An In vitroandIn silicoStudy	17
Lobaplatin Induces Pyroptosis in Cervical Cancer Cells via the Caspase-3/GSDME Pathway	17
Antitumor Activity of Zinc Nanoparticles Synthesized with Berberine on Human Epithelial Colorectal Adenocarcinoma (Caco-2) Cells through Acting on Cox-2/NF-kB and p53 Pathways	16
Cancer Nanotheranostics: A Nanomedicinal Approach for Cancer Therapy and Diagnosis	16
Recent Progress in the Development of Quinoline Derivatives for the Exploitation of Anti-Cancer Agents	16
Chemoresistance in Ovarian Cancer: Prospects for New Drugs	16
Recent Advancements in Organotin(IV) Complexes as Potent Cytotoxic Agents	16
Characterization and Anticancer Activities of Green Synthesized CuO Nanoparticles, A Review	16
Therapeutic Potentials and Mechanisms of Artemisinin and its Derivatives for Tumorigenesis and Metastasis	15
Anticancer Active Heterocyclic Chalcones: Recent Developments	15
Anti-Metastatic Effects of Lupeol via the Inhibition of MAPK/ERK Pathway in Lung Cancer	15
Recent Advances in Metal-Organic Frameworks as Anticancer Drug Delivery Systems: A Review	14
Organosulphur Compounds Induce Apoptosis and Cell Cycle Arrest in Cervical Cancer Cells via Downregulation of HPV E6 and E7 Oncogenes	14
The Engaged Role of Tumor Microenvironment in Cancer Metabolism: Focusing on Cancer-Associated Fibroblast and Exosome Mediators	14
A Mini-Review on Nano Technology in the Tumour Targeting Strategies: Drug Delivery to Cancer Cells	14
The Killing of Human Neuroblastoma Cells by the Small Molecule JQ1 Occurs in a p53-Dependent Manner	14
Panax notoginseng Saponins Promote Cell Death and Chemosensitivity in Pancreatic Cancer through the Apoptosis and Autophagy Pathways	14
Ruxolitinib Regulates the Autophagy Machinery in Multiple Myeloma Cells	14

Exploring the Molecular Mechanism of Cinnamic Acid-Mediated Cytotoxicity in Triple Negative MDA-MB-231 Breast Cancer Cells	14
Gemini Curcumin Suppresses Proliferation of Ovarian Cancer OVCAR-3 Cells via Induction of Apoptosis	13
lncRNAs as Potential Targets in Small Cell Lung Cancer: MYC -dependent Regulation	13
Eupatilin Inhibits the Proliferation and Migration of Prostate Cancer Cells through Modulation of PTEN and NF-κB Signaling	13
Isoquinolines: Important Cores in Many Marketed and Clinical Drugs	13
Apoptosis-Inducing Activity and Antiproliferative Effect of Gossypin on PC-3 Prostate Cancer Cells	13
The Anti-Breast Cancer Effects of Green-Synthesized Zinc Oxide Nanoparticles Using Carob Extracts	13
Anti-Tumor Effects of Osthole on Different Malignant Tissues: A Review of Molecular Mechanisms	13
BUB1B Promotes Proliferation of Prostate Cancer via Transcriptional Regulation of MELK	13
Alpha-Terpineol as Antitumor Candidate in Pre-Clinical Studies	13
Crude Methanol Extract of Rosin Gum Exhibits Specific Cytotoxicity against Human Breast Cancer Cells via Apoptosis Induction	13
Anti-Cancer Effects of Asiatic Acid, a Triterpene from Centilla asiatica L: A Review	12
A Critical Review on Anticancer Mechanisms of Natural Flavonoid Puerarin	12
Quinoline-3-carboxylate Derivatives: A New Hope as an Antiproliferative Agent	12
Prunus Armeniaca L. Seed Extract and Its Amygdalin Containing Fraction Induced Mitochondrial-Mediated Apoptosis and Autophagy in Liver Carcinogenesis	12
New Developments in Anti-Angiogenic Therapy of Cancer, Review and Update	12
Paclitaxel Nanoparticles Induce Apoptosis and Regulate TXR1, CYP3A4 and CYP2C8 in Breast Cancer and Hepatoma Cells	12
Discovery, Development and Design of Anthocyanins-Inspired Anticancer Agents: A Comprehensive Review	12
Protective Effect of Isothiocyanates from Cruciferous Vegetables on Breast Cancer: Epidemiological and Preclinical Perspectives	12
Therapy Resistance in Cancers: Phenotypic, Metabolic, Epigenetic and Tumour Microenvironmental Perspectives	11
Alkylating Agents, the Road Less Traversed, Changing Anticancer Therapy	11
Targeted Nanoparticles for Co-delivery of 5-FU and Nitroxoline, a Cathepsin B Inhibitor, in HepG2 Cells of Hepatocellular Carcinoma	11
Selective Photodynamic Effects on Breast Cancer Cells Provided by p123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery	11
Green Approaches for Cancers Management: An Effective Tool for Health Care	11
Cytotoxic Dehydroabietylamine Derived Compounds	11
New Derivatives of Bacteriopurpurin with Thiolated Au (I) Complexes: Dual Darkand Light Activated Antitumor Potency	11
Nilotinib, A Tyrosine Kinase Inhibitor, Suppresses the Cell Growth and Triggers Autophagy in Papillary Thyroid Cancer	11
Elucidation of S-Allylcysteine Role in Inducing Apoptosis by Inhibiting PD-L1 Expression in Human Lung Cancer Cells	11
Resveratrol and other Stilbenes: Effects on Dysregulated Gene Expression in Cancers and Novel Delivery Systems	11
A New Series of Antileukemic Agents: Design, Synthesis, In Vitro and In Silico Evaluation of Thiazole-Based ABL1 Kinase Inhibitors	11
UBE2L6 is Involved in Cisplatin Resistance by Regulating the Transcription of ABCB6	11
Quinoline-3-Carboxylic Acids: A Step Toward Highly Selective Antiproliferative Agent	11
Anlotinib Overcomes Multiple Drug Resistant Colorectal Cancer Cells via Inactivating PI3K/AKT Pathway	10
A Comprehensive Review on Journey of Pyrrole Scaffold Against Multiple Therapeutic Targets	10
Evaluation of the Diagnostic Properties of Serum hsa-miR-223-5p in the Detection of Gastric Cancer: A Case-Control Study	10
Recent Advances in Epidermal Growth Factor Receptor Inhibitors (EGFRIs) and their Role in the Treatment of Cancer: A Review	10
Retracted: miR-27b-3p Inhibits Invasion, Migration and Epithelial-mesenchymal Transition in Gastric Cancer by Targeting RUNX1 and Activation of the Hippo Signaling Pathway	10
Different Methods for Cell Viability and Proliferation Assay: Essential Tools in Pharmaceutical Studies	10
Periplogenin Activates ROS-ER Stress Pathway to Trigger Apoptosis via BIP-eIF2α- CHOP and IRE1α-ASK1-JNK Signaling Routes	10
Synthesis and Anti-Cancer Applications of Benzimidazole Derivatives - Recent Studies	10
Characterization of Gemcitabine Loaded Polyhydroxybutyrate Coated Magnetic Nanoparticles for Targeted Drug Delivery	10
Anti-Cancer Stem Cells Potentiality of an Anti-Malarial Agent Quinacrine: An Old Wine in a New Bottle	10
Pharmaceutical Aspects of Green Synthesized Silver Nanoparticles: A Boon to Cancer Treatment	10
The Effect of Phase Transition Temperature on Therapeutic Efficacy of Liposomal Bortezomib	10
Therapeutic Effects of Curcumin against Bladder Cancer: A Review of Possible Molecular Pathways	10
Exploring the Role of Phytochemicals as Potent Natural Photosensitizers in Photodynamic Therapy	10
Liposomal Drug Delivery and Its Potential Impact on Cancer Research	10
Synthesis of 1H-1,2,3-Triazole-Linked Quinoline-Isatin Molecular Hybrids as Anti-Breast Cancer and Anti-Methicillin-Resistant Staphylococcus aureus (MRSA) Agents	10
Cisplatin and Probiotic Biomass Loaded Pessaries for the Management of Cervical Cancer	10
Recent Development of Copolymeric Nano-Drug Delivery System for Paclitaxel	9
Serum Carboxypeptidase N1 Serves as a Potential Biomarker Complementing CA15-3 for Breast Cancer	9
Targeted Protein Degradation: An Emerging Therapeutic Strategy in Cancer	9
Design, Synthesis and Studies on Novel Polymeric Prodrugs of Erlotinib for Colon Drug Delivery	9
Lemongrass (Cymbopogon citratus (D.C.) Stapf) Presents Antitumoral Effect and Improves Chemotherapy Activity in Prostate Cancer Cells	9
The Citrus Flavanone Hesperetin Induces Apoptosis in CTCL Cells via STAT3/Notch1/NFκB-Mediated Signaling Axis	9
The Effect of a Newly Synthesized Ferrocene Derivative against MCF-7 Breast Cancer Cells and Spheroid Stem Cells through ROS Production and Inhibition of JAK2/STAT3 Signaling Pathway	9
The Chemosensitizing Role of Metformin in Anti-Cancer Therapy	9
Mitophagy in Carcinogenesis and Tumour Progression- A New Paradigm with Emerging Importance	9
The Smart Dual-Stimuli Responsive Nanoparticles for Controlled Anti-Tumor Drug Release and Cancer Therapy	9
Synthesis, Biological and Computational Evaluation of Novel 2,3-dihydro-2-aryl-4-(4- isobutylphenyl)-1,5-benzothiazepine Derivatives as Anticancer and Anti-EGFR Tyrosine Kinase Agents	9
Sanguinarine: A Double-Edged Sword of Anticancer and Carcinogenesis and Its Future Application Prospect	9
In Vitro Anticancer Evaluation of Some Synthesized 2H-Quinolinone and Halogenated 2H-Quinolinone Derivatives as Therapeutic Agents	9
Antitumor Mechanisms of Molecules Secreted by Trypanosoma cruzi in Colon and Breast Cancer: A Review	9
Propolis Extract Regulates microRNA Expression in Glioblastoma and Brain Cancer Stem Cells	9
Total Synthesis, Mechanism of Action, and Antitumor Efficacy of Camptothecin and Some of its Analogues	9
Azole-Pyrimidine Hybrid Anticancer Agents: A Review of Molecular Structure, Structure Activity Relationship, and Molecular Docking	9
Thieno[2,3-d]pyrimidin-4(3H)-one Derivatives of Benzimidazole as Potential Anti- Breast Cancer (MDA-MB-231, MCF-7) Agents	9
Design, Synthesis, Molecular Docking, and Anticancer Evaluation of Pyrazole Linked Pyrazoline Derivatives with Carbothioamide Tail as EGFR Kinase Inhibitors	9
Deglucohellebrin: A Potent Agent for Glioblastoma Treatment	9
Anlotinib Inhibits Cell Proliferation, Migration and Invasion via Suppression of c-Met Pathway and Activation of ERK1/2 Pathway in H446 Cells	9
Human Papillomavirus E7 Oncoprotein Promotes Proliferation and Migration through the Transcription Factor E2F1 in Cervical Cancer Cells	9
The Ubiquitin-Proteasome Pathway and Epigenetic Modifications in Cancer	9
The Effect of Bitter Melon (Momordica charantia) Extract on the Uptake of 99mTc Labeled Paclitaxel: In Vitro Monitoring in Breast Cancer Cells	9
An Insight into Anticancer Bioactives from Punica granatum (Pomegranate)	8
Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines	8
Breast Cancer Targeted Treatment Strategies: Promising Nanocarrier Approaches	8
Andrographolide Inhibits Proliferation of Colon Cancer SW-480 Cells via Downregulating Notch Signaling Pathway	8
Current Developments in the Pyran-Based Analogues as Anticancer Agents	8
Design and Development of Triazole Derivatives as Prospective Anticancer Agents: A Review	8
Molecular Mechanisms of Chloroquine and Hydroxychloroquine Used in Cancer Therapy	8

Cepharanthine Regulates Autophagy via Activating the p38 Signaling Pathway in Lung Adenocarcinoma Cells	8
Activation of PI3K/Akt/NF-kB Signaling Mediates Swedish Snus Induced Proliferation and Apoptosis Evasion in the Rat Forestomach: Modulation by Blueberry	8
Novel bis-amide-based bis-thiazoles as Anti-colorectal Cancer Agents Through Bcl-2 Inhibition: Synthesis, In Vitro, and In Vivo studies	8
Cyclodextrin-Based Nanosystems as Drug Carriers for Cancer Therapy	8
Advancements in the Use of Platinum Complexes as Anticancer Agents	8
Role of Collagen Regulators in Cancer Treatment: A Comprehensive Review	8
Role of Natural and Synthetic Flavonoids as Potential Aromatase Inhibitors in Breast Cancer: Structure-Activity Relationship Perspective	8
Synthesis and in Vitro Cytotoxicity Evaluation of Phenanthrene Linked 2,4- Thiazolidinediones as Potential Anticancer Agents	8
Melatonin Treatment Combined with TGF-β Silencing Inhibits Epithelial- Mesenchymal Transition in CF41 Canine Mammary Cancer Cell Line	8
Glipizide Combined with ANP Suppresses Breast Cancer Growth and Metastasis by Inhibiting Angiogenesis through VEGF/VEGFR2 Signaling	8
Downregulation of GPR4 and TCF7 Promotes Apoptosis and Inhibits Growth and Invasion of Ovarian Cancer Cells	8
Anti-MDR Effects of Quercetin and its Nanoemulsion in Multidrug-Resistant Human Leukemia Cells	8
Dose and Sequence Dependent Synergism from the Combination of Oxaliplatin with Emetine and Patulin Against Colorectal Cancer	8
In Vivo Biological Evaluation of Ethyl 4-(7-hydroxy-4-methyl-2-oxoquinolin-1- ylamino)-coumarin-3-carboxylate as an Antitumor Agent	8
Boosting Anti-tumour Immunity Using Adjuvant Apigenin	8
Mechanistic Study on Thymoquinone Conjugated ZnO Nanoparticles Mediated Cytotoxicity and Anticancer Activity in Triple-Negative Breast Cancer Cells	8
Down-Regulation of DDR1 Induces Apoptosis and Inhibits EMT through Phosphorylation of Pyk2/MKK7 in DU-145 and Lncap-FGC Prostate Cancer Cell Lines	8
Cucurbitacin IIb from Ibervillea sonorae Induces Apoptosis and Cell Cycle Arrest via STAT3 Inhibition	8
Recent Advances on Epidermal Growth Factor Receptor as a Molecular Target for Breast Cancer Therapeutics	8
Recombinant Human IL-11 Promotes Lung Adenocarcinoma A549 Cell Growth and EMT through Activating STAT3/HIF-1α/EMT Signaling Pathway	8
Induction of Apoptosis and Autophagy by Ternary Copper Complex Towards Breast Cancer Cells	8
Precision Oncology, Signaling, and Anticancer Agents in Cancer Therapeutics	8
Perturbation of HSP Network in MCF-7 Breast Cancer Cell Line Triggers Inducible HSP70 Expression and Leads to Tumor Suppression	8
Radioiodinated Ginger Compounds (6-gingerol and 6-shogaol) and Incorporation Assays on Breast Cancer Cells	8
Synthesis, In Vitro Antitumor Activity and Molecular Mechanism of Novel Furan Derivatives and their Precursors	8
Determination of Dysregulated miRNA Expression Levels by qRT-PCR after the Application of Usnic Acid to Breast Cancer	7
Celastrol Inhibits the Proliferation and Decreases Drug Resistance of Cisplatin- Resistant Gastric Cancer SGC7901/DDP Cells	7
Targeting Breast Cancer Cells with G4 PAMAM Dendrimers and Valproic Acid Derivative Complexes	7
Isovitexin Inhibits Stemness and Induces Apoptosis in Hepatocellular Carcinoma SK-Hep-1 Spheroids by Upregulating miR-34a Expression	7
Synthesis, Biological Evaluation and Molecular Docking Study of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics	7
Is It Time to Consider the Androgen Receptor as a Therapeutic Target in Breast Cancer?	7
The Antitumor Activity of a Novel Fluorobenzamidine against Dimethylhydrazine- Induced Colorectal Cancer in Rats	7
Anticancer Potential of Azole Containing Marine Natural Products: Current and Future Perspectives	7
Anticancer Potential of Mefenamic Acid Derivatives with Platelet-Derived Growth Factor Inhibitory Property	7
Synergistic Role of Thymoquinone on Anticancer Activity of 5-Fluorouracil in Triple Negative Breast Cancer Cells	7
MPEG-PCL Nanomicelles Platform for Synergistic Metformin and Chrysin Delivery to Breast Cancer in Mice	7
Encapsulation by Electrospraying of Anticancer Compounds from Jackfruit Extract (Artocarpus heterophyllus Lam): Identification, Characterization and Antiproliferative Properties	7
Propofol and Sevoflurane Alleviate Malignant Biological Behavior and Cisplatin Resistance of Xuanwei Lung Adenocarcinoma by Modulating the Wnt/β-catenin Pathway and PI3K/AKT Pathway	7
Application of Nanocellulose Derivatives as Drug Carriers; A Novel Approach in Drug Delivery	7
Wogonin Induces Cell Cycle Arrest and Apoptosis of Hepatocellular Carcinoma Cells by Activating Hippo Signaling	7
Anticancer Perspectives on the Fungal-Derived Polyphenolic Hispolon	7
Preparation, Characterization and In Vitro Biological Evaluation of Novel Curcumin Derivatives as Cytotoxic and Apoptosis-Inducing Agents	7
The Antitumor Activity of Ginger against Colorectal Cancer Induced by Dimethylhydrazine in Rats	7
Anticancer Potential of Doxorubicin in Combination with Green-Synthesized Silver Nanoparticle and its Cytotoxicity Effects on Cardio-Myoblast Normal Cells	7
Dual Human Carbonic Anhydrase/Cyclooxygenase-2 Inhibitors: A Promising Approach for Cancer Treatment	7
MicroRNA-520c-3p Modulates Doxorubicin-Chemosensitivity in HepG2 Cells	7
Zanthoxylum bungeanum Seed Oil Elicits Autophagy and Apoptosis in Human Laryngeal Tumor Cells via PI3K/AKT/mTOR Signaling Pathway	7
Linc01559 Served as a Potential Oncogene and Promoted Resistance of Hepatocellular Carcinoma to Oxaliplatin by Directly Sponging miR-6783-3p	7
Half-Lantern Cyclometalated Platinum(II) Complexes as Anticancer Agents: Molecular Docking, Apoptosis, Cell Cycle Analysis, and Cytotoxic Activity Evaluations	7
Novel Scopoletin Derivatives Kill Cancer Cells by Inducing Mitochondrial Depolarization and Apoptosis	7
Hyperglycemia Promotes Pancreatic Cancer Initiation and Progression by Activating the Wnt/β-Catenin Signaling Pathway	7
Pistachio Green Hull Extract Induces Apoptosis through Multiple Signaling Pathways by Causing Oxidative Stress on Colon Cancer Cells	7
Improving Cytotoxicity against Breast Cancer Cells by Using Mixed-Ligand Ruthenium(II) Complexes of 2,2'-Bipyridine, Amino Acid, and Nitric Oxide Derivatives as Potential Anticancer Agents	7
Chloroform Fraction of Methanolic Extract of Seeds of Annona muricata Induce S Phase Arrest and ROS Dependent Caspase Activated Mitochondria-Mediated Apoptosis in Triple-Negative Breast Cancer	7
Anti-Proliferative and Anti-Telomerase Effects of Blackberry Juice and Berry- Derived Polyphenols on HepG2 Liver Cancer Cells and Normal Human Blood Mononuclear Cells	7
MicroRNA-372-3p Predicts Response of TACE Patients Treated with Doxorubicin and Enhances Chemosensitivity in Hepatocellular Carcinoma	7
Metal-based Complexes as Potential Anti-cancer Agents	7
The Synthesis, Anticancer Activity, Structure-Activity Relationships and Molecular Modelling Studies of Novel Isoindole-1,3(2H)-dione Compounds Containing Different Functional Groups	7
Anti-Breast Cancer Activities of Ketoprofen-RGD Conjugate by Targeting Breast Cancer Stem-Like Cells and Parental Cells	7
Synthesis of Some Benzimidazole-derived Molecules and their Effects on PARP-1 Activity and MDA-MB-231, MDA-MB-436, MDA-MB-468 Breast Cancer Cell Viability	7
Pulsatilla saponin A Induces Apoptosis and Differentiation of Myeloma Cells	7
Nuciferine Inhibits Skin Cutaneous Melanoma Cell Growth by Suppressing TLR4/NF-κB Signaling	7
Phyto-Phospholipid Complexation as a Novel Drug Delivery System for Management of Cancer with Better Bioavailability: Current Perspectives and Future Prospects	7
Inhibition of Growth of Esophageal Cancer by Alantolactone via Wnt/β- Catenin Signaling	7
Probiotics for the Chemoprotective Role against the Toxic Effect of Cancer Chemotherapy	7
The Radio-Sensitizing Effect of Pharmacological Concentration of Ascorbic Acid on Human Pancreatic Cancer Cells	7
Heterocyclic Compounds: Importance in Anticancer Drug Discovery	7
Synthesis and Biological Evaluation of Coumarin Carboxamides as Selective and Potent Inhibitors of Carbonic Anhydrases IX and XII	7
Evaluation of Anti-Tumor Potential of Lactobacillus acidophilus ATCC4356 Culture Supernatants in MCF-7 Breast Cancer	7
Recent Developments in Oxazole Derivatives as Anticancer Agents: Review on Synthetic Strategies, Mechanism of Action and SAR Studies	7
A Ferrocene Derivative Reduces Cisplatin Resistance in Breast Cancer Cells through Suppression of MDR-1 Expression and Modulation of JAK2/STAT3 Signaling Pathway	7
One Pot Green Synthesis of Doxorubicin and Curcumin Loaded Magnetic Nanoparticles and Cytotoxicity Studies	7
Botanical Therapeutics (Part II): Antimicrobial and In Vitro Anticancer Activity against MCF7 Human Breast Cancer Cells of Chamomile, Parsley and Celery Alcoholic Extracts	7
A Focused Review on Molecular Signalling Mechanisms of Ginsenosides Anti-Lung Cancer and Anti-inflammatory Activities	7
Smoking is Associated with Lung Adenocarcinoma and Lung Squamous Cell Carcinoma Progression through Inducing Distinguishing lncRNA Alterations in Different Genders	7
In-vitro Evaluation of Isatin Derivatives as Potent Anti-Breast Cancer Agents against MCF-7, MDA MB 231, MDA-MB 435 and MDA-MB 468 Breast Cancers Cell Lines: A Review	7
Bioactive Heterocyclic Compounds as Potential Therapeutics in the Treatment of Gliomas: A Review	6
Natural-Derived Molecules as a Potential Adjuvant in Chemotherapy: Normal Cell Protectors and Cancer Cell Sensitizers	6
A Comparison of the Anti-Cancer Effects of Free and PLGA-PAA Encapsulated Hydroxytyrosol on the HT-29 Colorectal Cancer Cell Line	6
Urtica dioica Extract Inhibits Cell Proliferation and Induces Apoptosis in HepG2 and HTC116 as Gastrointestinal Cancer Cell Lines	6
Synthesis and Cytotoxic Properties of New Substituted Glycosides-Indole Conjugates as Apoptosis Inducers in Cancer Cells	6
Application of Selenium Nanoparticles in Localized Drug Targeting for Cancer Therapy	6
Novel Dihydropyrimidinone-Derived Selenoesters as Potential Cytotoxic Agents to Human Hepatocellular Carcinoma: Molecular Docking and DNA Fragmentation	6
Cinobufotalin Induces Ferroptosis to Suppress Lung Cancer Cell Growth by lncRNA LINC00597/hsa-miR-367-3p/TFRC Pathway via Resibufogenin	6
Lemon Juice as a Biocatalyst Under Ultrasound Irradiation: Synthesis and Pharmacological Evaluation of 2-amino 1,3,4-thiadiazoles	6
High Diagnostic and Prognostic Value of miRNAs Compared with the Carcinoembryonic Antigen As A Traditional Tumor Marker	6
Anticancer Effects of Cinnamaldehyde Through Inhibition of ErbB2/HSF1/LDHA Pathway in 5637 Cell Line of Bladder Cancer	6
Recent Advances in Synthesis and Anticancer Potential of Triazole-Containing Scaffolds	6
Erinacerins, Novel Glioma Inhibitors from Hericium erinaceus, Induce Apoptosis of U87 Cells through Bax/Capase-2 Pathway	6
Association of GRP78, HIF-1α and BAG3 Expression with the Severity of Chronic Lymphocytic Leukemia	6
Apatinib Inhibits Stem Properties and Malignant Biological Behaviors of Breast Cancer Stem Cells by Blocking Wnt/β-catenin Signal Pathway through Downregulating LncRNA ROR	6
Utilization of Lipid-based Nanoparticles to Improve the Therapeutic Benefits of Bortezomib	6
Pisosterol Induces G2/M Cell Cycle Arrest and Apoptosis via the ATM/ATR Signaling Pathway in Human Glioma Cells	6
Drug Repurposing Strategies for Non-cancer to Cancer Therapeutics	6
High Expression of SIRT1 Associates with the Doxorubicin Resistance of Breast Cancer through the Activation of Akt	6