Clinical Epigenetics

Papers
(The median citation count of Clinical Epigenetics is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Disrupted methylation patterns at birth persist in early childhood: a prospective cohort analysis104
DNA methylation patterns associated with konzo in Sub-Saharan Africa89
Psychostimulant-induced aberrant DNA methylation in an in vitro model of human peripheral blood mononuclear cells85
Novel genetic variants of KHDC3L and other members of the subcortical maternal complex associated with Beckwith–Wiedemann syndrome or Pseudohypoparathyroidism 1B and multi-locus imprinting disturbance76
Technical considerations in PCR-based assay design for diagnostic DNA methylation cancer biomarkers64
Novel epigenetic network biomarkers for early detection of esophageal cancer62
Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients56
An epigenome-wide study of DNA methylation profiles and lung function among American Indians in the Strong Heart Study53
Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer43
Defining post-acute COVID-19 syndrome (PACS) by an epigenetic biosignature in peripheral blood mononuclear cells41
Multi-omic alterations of the SWI/SNF complex define a clinical subgroup in lung adenocarcinoma41
Aberrant epigenetic and transcriptional events associated with breast cancer risk40
Cross talk between acetylation and methylation regulators reveals histone modifier expression patterns posing prognostic and therapeutic implications on patients with colon cancer39
Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival39
Maternal epigenetic clocks measured during pregnancy do not predict gestational age at delivery or offspring birth outcomes: a replication study in metropolitan Cebu, Philippines37
Whole blood methylome-derived features to discriminate endocrine hypertension37
Predicting disease-free survival in colorectal cancer by circulating tumor DNA methylation markers35
Plasma lipid profiles in early adulthood are associated with epigenetic aging in the Coronary Artery Risk Development in Young Adults (CARDIA) Study34
Circulating cell-free DNA methylation mirrors alterations in cerebral patterns in epilepsy33
Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro dat32
Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA)31
First step towards a consensus strategy for multi-locus diagnostic testing of imprinting disorders31
Epigenome-wide DNA methylation profiling of conditioned pain modulation in individuals with non-specific chronic low back pain30
Fetal exposure to phthalates and bisphenols and DNA methylation at birth: the Generation R Study30
Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer29
Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach29
Maternal–fetal stress and DNA methylation signatures in neonatal saliva: an epigenome-wide association study28
Epigenome-wide association study of lung function in Latino children and youth with asthma28
Dynamic patterns of blood lipids and DNA methylation in response to statin therapy28
Altered DNA methylation in estrogen-responsive repetitive sequences of spermatozoa of infertile men with shortened anogenital distance27
Aberrant DNA hydroxymethylation reshapes transcription factor binding in myeloid neoplasms27
OXTR DNA methylation differentiates men on the obesity spectrum with and without binge eating disorder25
Epigenetics of early-life adversity in youth: cross-sectional and longitudinal associations25
Epigenetics of type 2 diabetes and diabetes-related outcomes in the Strong Heart Study25
Association of nutritional glycaemic indices with global DNA methylation patterns: results from the Moli-sani cohort25
Integrated 5-hydroxymethylcytosine and fragmentation signatures as enhanced biomarkers in lung cancer24
The emerging role of epigenetic regulation in the progression of silicosis23
Bisulfite profiling of the MGMT promoter and comparison with routine testing in glioblastoma diagnostics23
Decreased mitochondrial D-loop region methylation mediates an increase in mitochondrial DNA copy number in CADASIL23
Identification of differentially methylated regions in rare diseases from a single-patient perspective23
Correction to: ZMYND10, an epigenetically regulated tumor suppressor, exerts tumor-suppressive functions via miR145-5p/NEDD9 axis in breast cancer22
Why epigenetics is (not) a biosocial science and why that matters22
A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence22
Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature21
Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder21
JIB-04, a histone demethylase Jumonji C domain inhibitor, regulates phenotypic switching of vascular smooth muscle cells20
Lifetime exposure to smoking, epigenetic aging, and morbidity and mortality in older adults20
Investigating pathological epigenetic aberrations by epi-proteomics20
Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer19
Serum level of total histone 3, H3K4me3, and H3K27ac after non-emergent cardiac surgery suggests the persistence of smoldering inflammation at 3 months in an adult population19
Pembrolizumab plus azacitidine in patients with chemotherapy refractory metastatic colorectal cancer: a single-arm phase 2 trial and correlative biomarker analysis19
Integrated multi-omics analyses reveal that BCAM is associated with epigenetic modification and tumor microenvironment subtypes of clear cell renal cell carcinoma19
Epigenome-wide epidemiologic studies of human immunodeficiency virus infection, treatment, and disease progression18
Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer18
Epigenetic tumor heterogeneity in the era of single-cell profiling with nanopore sequencing18
The spectrum of tuberculosis described as differential DNA methylation patterns in alveolar macrophages and alveolar T cells18
SEEMLIS: a flexible semi-automated method for enrichment of methylated DNA from low-input samples18
NAA60 (HAT4): the newly discovered bi-functional Golgi member of the acetyltransferase family18
Integrated single-cell RNA-seq and DNA methylation reveal the effects of air pollution in patients with recurrent spontaneous abortion17
Characterising sex differences of autosomal DNA methylation in whole blood using the Illumina EPIC array17
Cell-type heterogeneity: Why we should adjust for it in epigenome and biomarker studies17
Association of prenatal alcohol exposure with offspring DNA methylation in mammals: a systematic review of the evidence17
A core of differentially methylated CpG loci in gMDSCs isolated from neonatal and adult sources16
Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells16
Effect of menopausal hormone therapy on methylation levels in early and late postmenopausal women16
Evaluation of cross-platform compatibility of a DNA methylation-based glucocorticoid response biomarker16
5-Hydroxymethylation alterations in cell-free DNA reflect molecular distinctions of diffuse large B cell lymphoma at different primary sites16
The CpG island methylator phenotype increases the risk of high-grade squamous intraepithelial lesions and cervical cancer16
Gender-affirming hormone therapy induces specific DNA methylation changes in blood16
DNA methylation and aeroallergen sensitization: The chicken or the egg?16
Immune profiles and DNA methylation alterations related with non-muscle-invasive bladder cancer outcomes16
Low reliability of DNA methylation across Illumina Infinium platforms in cord blood: implications for replication studies and meta-analyses of prenatal exposures16
Persistent blood DNA methylation changes one year after SARS-CoV-2 infection15
Shifts in the immunoepigenomic landscape of monocytes in response to a diabetes-specific social support intervention: a pilot study among Native Hawaiian adults with diabetes15
Differentially hypomethylated cell-free DNA and coronary collateral circulation15
Correction: miR-29c plays a suppressive role in breast cancer by targeting the TIMP3/STAT1/FOXO1 pathway15
Bariatric surgery-induced weight loss and associated genome-wide DNA-methylation alterations in obese individuals15
Chromatin accessibility and transcriptome integrative analysis revealed AP-1-mediated genes potentially modulate histopathology features in psoriasis15
A deep learning model for early risk prediction of heart failure with preserved ejection fraction by DNA methylation profiles combined with clinical features15
LINE-1 hypomethylation is associated with poor outcomes in locoregionally advanced oropharyngeal cancer15
Gestational age acceleration is associated with epigenetic biomarkers of prenatal physiologic stress exposure14
Novel blood-based FUT7 DNA methylation is associated with lung cancer: especially for lung squamous cell carcinoma14
Characterisation of ethnic differences in DNA methylation between UK-resident South Asians and Europeans14
Comparative analysis of the DNA methylation landscape in CD4, CD8, and B memory lineages14
Liquid biopsy, using a novel DNA methylation signature, distinguishes pancreatic adenocarcinoma from benign pancreatic disease14
Interpretation of the role of germline and somatic non-coding mutations in cancer: expression and chromatin conformation informed analysis14
Detection of ovarian cancer using plasma cell-free DNA methylomes14
Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett’s esophagus13
Identification of DNA methylation-regulated genes as potential biomarkers for coronary heart disease via machine learning in the Framingham Heart Study13
Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes13
Altered methylation pattern in EXOC4 is associated with stroke outcome: an epigenome-wide association study13
Relative contributions of six lifestyle- and health-related exposures to epigenetic aging: the Coronary Artery Risk Development in Young Adults (CARDIA) Study13
An examination of mediation by DNA methylation on birthweight differences induced by assisted reproductive technologies13
Advantages of vitrification preservation in assisted reproduction and potential influences on imprinted genes13
Regulation of oxytocin receptor gene expression in obsessive–compulsive disorder: a possible role for the microbiota-host epigenetic axis13
Chidamide and venetoclax synergistically exert cytotoxicity on multiple myeloma by upregulating BIM expression13
The mediating effect of DNA methylation in the association between maternal sleep during pregnancy and offspring adiposity status: a prospective cohort study13
Distinguishing transgender DNA methylation13
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