Clinical Epigenetics

Papers
(The H4-Index of Clinical Epigenetics is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
The dynamic broad epigenetic (H3K4me3, H3K27ac) domain as a mark of essential genes110
DNA methyltransferase inhibitors combination therapy for the treatment of solid tumor: mechanism and clinical application102
Epigenome-wide association studies: current knowledge, strategies and recommendations83
Blood DNA methylation and COVID-19 outcomes80
Mitochondrial metabolism and DNA methylation: a review of the interaction between two genomes77
Cellular reprogramming and epigenetic rejuvenation66
Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects64
Advances in epigenetic therapeutics with focus on solid tumors62
Effects of metabolic memory on inflammation and fibrosis associated with diabetic kidney disease: an epigenetic perspective59
Epigenetic regulation of inflammation in periodontitis: cellular mechanisms and therapeutic potential56
Epigenetic alterations and advancement of treatment in peripheral T-cell lymphoma53
Sperm DNA methylation epimutation biomarker for paternal offspring autism susceptibility53
Epigenetic modification mechanisms involved in keloid: current status and prospect52
Gene body methylation in cancer: molecular mechanisms and clinical applications52
Current understanding of epigenetics mechanism as a novel target in reducing cancer stem cells resistance52
Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans49
Finding an easy way to harmonize: a review of advances in clinical research and combination strategies of EZH2 inhibitors46
DNA methylation biomarkers of myocardial infarction and cardiovascular disease45
Tackling tumor microenvironment through epigenetic tools to improve cancer immunotherapy44
Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression44
DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures44
Characterising sex differences of autosomal DNA methylation in whole blood using the Illumina EPIC array44
DNA methylation of blood cells is associated with prevalent type 2 diabetes in a meta-analysis of four European cohorts42
SMYD3: a regulator of epigenetic and signaling pathways in cancer42
Clinical epigenetics settings for cancer and cardiovascular diseases: real-life applications of network medicine at the bedside42
The ENmix DNA methylation analysis pipeline for Illumina BeadChip and comparisons with seven other preprocessing pipelines41
Hypoxia promotes the metastasis of pancreatic cancer through regulating NOX4/KDM5A-mediated histone methylation modification changes in a HIF1A-independent manner41
Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice40
A urine-based DNA methylation assay to facilitate early detection and risk stratification of bladder cancer40
DNA methylation mediates the effect of maternal smoking on offspring birthweight: a birth cohort study of multi-ethnic US mother–newborn pairs39
The dark side of histones: genomic organization and role of oncohistones in cancer39
Methylated circulating tumor DNA as a biomarker for colorectal cancer diagnosis, prognosis, and prediction39
Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer38
The role of epigenetic mechanisms in the regulation of gene expression in the cyclical endometrium38
DNA methylation signatures of incident coronary heart disease: findings from epigenome-wide association studies36
Association of peripheral blood DNA methylation level with Alzheimer’s disease progression36
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