OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical Epigenetics is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Novel epigenetic network biomarkers for early detection of esophageal cancer	150
Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients	100
Disrupted methylation patterns at birth persist in early childhood: a prospective cohort analysis	78
DNA methylation patterns associated with konzo in Sub-Saharan Africa	76
Psychostimulant-induced aberrant DNA methylation in an in vitro model of human peripheral blood mononuclear cells	72
Novel genetic variants of KHDC3L and other members of the subcortical maternal complex associated with Beckwith–Wiedemann syndrome or Pseudohypoparathyroidism 1B and multi-locus imprinting disturbance	69
Technical considerations in PCR-based assay design for diagnostic DNA methylation cancer biomarkers	61
An epigenome-wide study of DNA methylation profiles and lung function among American Indians in the Strong Heart Study	59
Whole blood methylome-derived features to discriminate endocrine hypertension	52
Aberrant epigenetic and transcriptional events associated with breast cancer risk	50
Defining post-acute COVID-19 syndrome (PACS) by an epigenetic biosignature in peripheral blood mononuclear cells	42
Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer	42
Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival	40
Multi-omic alterations of the SWI/SNF complex define a clinical subgroup in lung adenocarcinoma	39
Epigenetic adaptations of the masticatory mucosa to periodontal inflammation	38
Cross talk between acetylation and methylation regulators reveals histone modifier expression patterns posing prognostic and therapeutic implications on patients with colon cancer	38
Epigenome-wide DNA methylation profiling of conditioned pain modulation in individuals with non-specific chronic low back pain	37
First step towards a consensus strategy for multi-locus diagnostic testing of imprinting disorders	36
Circulating cell-free DNA methylation mirrors alterations in cerebral patterns in epilepsy	36
Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA)	35
Predicting disease-free survival in colorectal cancer by circulating tumor DNA methylation markers	35
Maternal epigenetic clocks measured during pregnancy do not predict gestational age at delivery or offspring birth outcomes: a replication study in metropolitan Cebu, Philippines	35
Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer	34
Fetal exposure to phthalates and bisphenols and DNA methylation at birth: the Generation R Study	33
Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro dat	32

Epigenome-wide association studies: current knowledge, strategies and recommendations	31
Plasma lipid profiles in early adulthood are associated with epigenetic aging in the Coronary Artery Risk Development in Young Adults (CARDIA) Study	31
Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach	30
Reproductive history and blood cell DNA methylation later in life: the Young Finns Study	29