OOIR: Observatory of International Research

Papers

(The TQCC of Translational Stroke Research is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Three Pillars of Recovery After Aneurysmal Subarachnoid Hemorrhage: A Narrative Review	69
Adjunctive Human Urinary Kallidinogenase Enhances the Cognitive and Hemodynamic Outcomes of Anterior Circulation Stenting	67
HDAC9 Deficiency Upregulates cGMP-dependent Kinase II to Mitigate Neuronal Apoptosis in Ischemic Stroke	64
Blood Oxygenation Level–Dependent Cerebrovascular Reactivity–Derived Steal Phenomenon May Indicate Tissue Reperfusion Failure After Successful Endovascular Thrombectomy	55
Correction to: Implication of MicroRNA503 in Brain Endothelial Cell Function and Ischemic Stroke	50
Crosstalk Between Signaling Stroke Cascade and Therapeutic Receptors PPAR-γ, ROCK, CB1R, and CB2R: From Mechanism to Therapies	44
Reporting Compliance and Factors Influencing Timeliness of Stroke-Related Trial Results on ClinicalTrials.gov	40
Cerebral Hemodynamics Underlying Artery-to-Artery Embolism in Symptomatic Intracranial Atherosclerotic Disease	40
Decompressive Craniectomy Decreases Neuroinflammation after Ischemic Stroke in Mice	39
Anti-Apoptotic Effects of AMPA Receptor Antagonist Perampanel in Early Brain Injury After Subarachnoid Hemorrhage in Mice	36
Prevalence and Predictors of Hemorrhagic Foci on Long-term Follow-up MRI of Recent Single Subcortical Infarcts	33
Cerebral Perfusion Characteristics and Dynamic Brain Structural Changes in Stroke-Prone Renovascular Hypertensive Rats: A Preclinical Model for Cerebral Small Vessel Disease	31
Unveiling the Hidden Impact: Hematoma Volumes Unravel Circuit Disruptions in Intracerebral Hemorrhage	28
Comparison of Long-Term Outcomes in Ruptured Diffuse Brain Arteriovenous Malformations Between Interventional Therapy and Conservative Management	26
Associations Between Early Functional Brain Network Topology and 6-Month Upper Limb Motor Outcomes in Stroke Patients	25
Delayed Chronic Acidic Postconditioning Improves Poststroke Motor Functional Recovery and Brain Tissue Repair by Activating Proton-Sensing TDAG8	25
Multimodal Risk Stratification Clue of Carotid Bifurcation Plaques: A Cross-Sectional Observational Study of Vector Flow Imaging, Plaque-RADS, and Clinical Factors	25
Remote Ischemic Postconditioning Attenuates Neuroinflammation and Suggests a Potential Benefit for Early Neurological Recovery after Subarachnoid Hemorrhage via the IL-9/JAK2-STAT5 Signaling Pathway	25
All Three Supersystems—Nervous, Vascular, and Immune—Contribute to the Cortical Infarcts After Subarachnoid Hemorrhage	24
Remote Ischemic Post-conditioning Reduces Cognitive Impairment in Rats Following Subarachnoid Hemorrhage: Possible Involvement in STAT3/STAT5 Phosphorylation and Th17/Treg Cell Homeostasis	24
Cerebral Small Vessel Disease: a Review of the Pathophysiological Mechanisms	23
Inhibition of USP30 Promotes Mitophagy by Regulating Ubiquitination of MFN2 by Parkin to Attenuate Early Brain Injury After SAH	23
Internal Capsule Involvement Explains the Prognostic Impact of ASPECTS after Endovascular Thrombectomy for Large-Core Infarction	22
Intracerebral Administration of a Novel Self-Assembling Peptide Hydrogel Is Safe and Supports Cell Proliferation in Experimental Intracerebral Haemorrhage	22
Nomogram for Predicting Long-term Outcomes of Encephaloduroarteriosynangiosis in Toddlers with Moyamoya Disease: a Longitudinal and Cross-sectional Study	22

RNF213 p.Arg4810Lys Wild Type is Associated with De Novo Hemorrhage in Asymptomatic Hemispheres with Moyamoya Disease	22
Correction to: The Neuronal Ischemic Tolerance Is Conditioned by the Tp53 Arg72Pro Polymorphism	21
Distinct Cytokine Responses in Central and Systemic Compartments after Subarachnoid Haemorrhage	20
Quantitative Evaluation of Incomplete Stent Apposition in Intracranial Aneurysms Using Optical Coherence Tomography: a Porcine Model Study	20
Impact of Neutrophil Extracellular Traps on Clinical Outcome after Subarachnoid Hemorrhage: A Translational Narrative Review	20
Stroke Mechanisms in Intracranial Atherosclerotic Disease: A Modified Classification System and Clinical Implications	20
Comparative Outcomes of Combined Balloon Angioplasty and Intra-arterial Calcium Channel Blockers Versus Monotherapy for Cerebral Vasospasm Management: A Systematic Review and Meta-analysis	19
A Scoping Review of Preclinical Environmental Enrichment Protocols in Models of Poststroke to Set the Foundations for Translating the Paradigm to Clinical Settings	18
Correction to: An Alternative Photothrombotic Model of Transient Ischemic Attack	17
Correction to: The Mfn1‑βIIPKC Interaction Regulates Mitochondrial Dysfunction via Sirt3 Following Experimental Subarachnoid Hemorrhage	17
Opportunities for Neuroprotective Drugs in the Era of Vascular Recanalization	17
Cost-Effectiveness of Carotid Endarterectomy vs. Carotid Stenting: a Systematic Review and Meta-Analysis	16
Blood DNA Methylation Analysis Reveals a Distinctive Epigenetic Signature of Vasospasm in Aneurysmal Subarachnoid Hemorrhage	16
Direct Versus Indirect Bypass in Early-Stage Moyamoya (Suzuki I-III): A Propensity Score-Weighted Study	16
Methylated MFGE8 Promotes Early Brain Injury After Subarachnoid Hemorrhage and Inhibiting Autophagy of Nerve Cell	16
Alpha-Asarone Ameliorates Neurological Dysfunction of Subarachnoid Hemorrhagic Rats in Both Acute and Recovery Phases via Regulating the CaMKII-Dependent Pathways	15
Switching Off Vascular MAPK Signaling: A Novel Strategy to Prevent Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage	15
Vascular Endothelial Growth Factor-A and Collateral Circulation in Patients with Acute Ischemic Stroke due to Intracranial Large Vessel Occlusion	15
Prevention of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage—Summary of Existing Clinical Evidence	15
Correction to: Iron‑Induced Hydrocephalus: The Role of Choroid Plexus Stromal Macrophages	15
Use of Tirofiban to Prevent Ischemic Events in Patients with CYP2C19 Loss-of-Function Alleles during Flow Diversion of Intracranial Aneurysm: A Multicenter Cohort Study	15
Quantitative Cerebrovascular Analysis for Improved Prediction of Post-Stroke Complications	14
Comprehensive Profiling of Secreted Factors in the Cerebrospinal Fluid of Moyamoya Disease Patients	14
A Novel Hybrid of Telmisartan and Borneol Ameliorates Neuroinflammation and White Matter Injury in Ischemic Stroke Through ATF3/CH25H Axis	14
Minimally Invasive Intracerebral Hemorrhage Evacuation Improves Pericavity Cerebral Blood Volume	14
Association of Genetic Variants with Postoperative Donor Artery Development in Moyamoya Disease: RNF213 and Other Moyamoya Angiopathy-Related Gene Analysis	14
Correction to: Blood DNA Methylation Analysis Reveals a Distinctive Epigenetic Signature of Vasospasm in Aneurysmal Subarachnoid Hemorrhage	14
Integrating Bulk RNA and Single-Cell Sequencing Data Unveils Efferocytosis Patterns and ceRNA Network in Ischemic Stroke	14
The Hyperacute Phase of Cerebral Infarction in a Swine Model Investigated with Cone-Beam CT Perfusion Imaging	14
What to Measure in Aneurysmal Subarachnoid Haemorrhage Research—An International Delphi Survey	14
Revisiting Transcranial Light Stimulation as a Stroke Therapeutic—Hurdles and Opportunities	13
Neuroprotection of Stem Cells Against Ischemic Brain Injury: From Bench to Clinic	13
Jugular Vein Evans Blue Injection for Blood–Brain Barrier Assessment Following Hemorrhagic Stroke in a Mouse Model	13
Motor Rehabilitation Provides Modest Functional Benefits After Intracerebral Hemorrhage: a Systematic Review and Meta-Analysis of Translational Rehabilitation Studies	13
Integrated Strategies for Targeting Arteriogenesis and Angiogenesis After Stroke	12
Modulation of the Immunological Milieu in Acute Aneurysmal Subarachnoid Hemorrhage: The Potential Role of Monocytes Through CXCL10 Secretion	12
Cilostazol Alleviates Delayed Cerebral Ischemia After Subarachnoid Hemorrhage by Attenuating Microcirculatory Dysfunction	12
Promising Cerebral Blood Flow Enhancers in Acute Ischemic Stroke	12
Advances in the Genetics and Molecular Biology of Brain Arteriovenous Malformations	12
Collaterals and Elusive Ischemic Penumbra	12
Plasma Metabolites of Kynurenine Pathway and Risk of Stroke in the General Population: A Nested Case–control Study	11
Acetylation of p53 in the Cerebral Cortex after Photothrombotic Stroke	11
Dysregulated Genes and Signaling Pathways in the Formation and Rupture of Intracranial Aneurysm	11
Non-Linear Temporal Dynamics of Endothelial Progenitor Cells After Stroke: Associations with Perfusion Imaging, ASPECTs and Functional Outcome	11
Spatial and Temporal Assessment of Cerebral Blood Flow in a Novel Piglet Model of Neonatal Arterial Ischemic Stroke	11
Roles and Potential Mechanisms of Endothelial Cell-Derived Extracellular Vesicles in Ischemic Stroke	11
Current Status and Progress in Stem Cell Therapy for Intracerebral Hemorrhage	11
SLC45A3 Serves as a Potential Therapeutic Biomarker to Attenuate White Matter Injury After Intracerebral Hemorrhage	11
Cerebral Small Vessel Disease and Infarct Growth in Acute Ischemic Stroke Treated with Intravenous Thrombolysis	11
Transcutaneous Auricular Vagus Nerve Stimulation Reduces Inflammatory Biomarkers after Large Vessel Occlusion Stroke: Results of a Prospective Randomized Open-Label Blinded Endpoint Trial	10

Accounting for Truncation Artifacts in Angiographic Perfusion	10
Hyperthermia and Early Growth of Cerebral Infarct: The Potential Role of Blood–Brain Barrier Permeability	10
Symmetric Dimethylarginine for Risk Stratification of Cardioembolic Stroke	10
Cerebral Small Vessel Disease and Blood-Brain Barrier Disruption: Mechanisms and Therapeutic Strategies in Cognitive Impairment	10
Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Swallowing Function in Post-stroke Dysphagia: A Randomized Controlled Study	10
TdCCA with Dual-Modal Signal Fusion: Degenerated Occipital and Frontal Connectivity of Adult Moyamoya Disease for Early Identification	10
Brain Maturation as a Fundamental Factor in Immune-Neurovascular Interactions in Stroke	10
Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 (LOX-1): A Potential Therapeutic Target in Ischemic Stroke	10
Temporal Pattern and Clinical Value of Serum GFAP in Acute Ischemic Stroke: Results from Two Prospective German Cohorts	10
Effects of New-Generation Antiepileptic Drug Prophylaxis on Delayed Neurovascular Events After Aneurysmal Subarachnoid Hemorrhage	9
PIP4K2A Attenuates Cerebral Ischemia/Reperfusion Injury by Reducing the TRIB3-p62 Complex Burden and Modulating AKT/mTOR Signaling	9
Reinventing the Penumbra — the Emerging Clockwork of a Multi-modal Mechanistic Paradigm	9
Recurrence of Cerebral Arteriovenous Malformation Following Complete Obliteration Through Endovascular Embolization	9
Theta Frequency Electromagnetic Stimulation Enhances Functional Recovery After Stroke	9
Neural Stem Cell Extracellular Vesicles Carrying YBX1 Inhibited Neuronal Pyroptosis Through Increasing m6A-modified GPR30 Stability and Expression in Ischemic Stroke	9
The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium	9
Imaging of Intracranial Aneurysms: A Review of Standard and Advanced Imaging Techniques	9
Correction to: Endogenous Neural Stem Cell–induced Neurogenesis after Ischemic Stroke: Processes for Brain Repair and Perspectives	9
Inverse Association between the Body Mass Index and the Incidence of Unruptured Intracranial Aneurysms—Insights from the Hamburg City Health Population Study	9
Letter to the Editor	9
Predictive Utility of Cerebral Blood Flow Transients in Experimental Stroke	9
Mesenchymal Stem Cells Overexpressing FGF21 Preserve Blood-Brain Barrier Integrity in Experimental Ischemic Stroke	9
Correction to: Recombinant Adiponectin Peptide Ameliorates Brain Injury Following Intracerebral Hemorrhage by Suppressing Astrocyte-Derived Inflammation via the Inhibition of Drp1-Mediated Mitochondri	8
Catecholamine-Induced Inflammasome Activation in the Heart Following Photothrombotic Stroke	8
Long-Term Outcomes of Stereotactic Radiosurgery Focused Treatment of Brain Arteriovenous Malformations Based on Rupture Status: A Systematic Review and Meta-Analysis	8
Except for Robust Outliers, Rapamycin Increases Lesion Burden in a Murine Model of Cerebral Cavernous Malformations	8
Correction to: The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium	8
New Drug Developments for Stroke: from Basics to Clinics	8
Blockade of the Platelet-Driven CXCL7-CXCR1/2 Inflammatory Axis Prevents Murine Cerebral Aneurysm Formation and Rupture	8
Loss of Vascular TMEM16A Impairs Cerebral Autoregulation and Exacerbates Ischemia–reperfusion Injury	8
Simultaneous Four Supratentorial Lesions Predict Tube Dependency Due to an Impaired Anticipatory Phase of Ingestion	8
Glial Cell Reprogramming in Ischemic Stroke: A Review of Recent Advancements and Translational Challenges	8