OOIR: Observatory of International Research

Papers

(The median citation count of Cellular and Molecular Bioengineering is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Acteoside-Loaded Self-Healing Hydrogel Enhances Skin Wound Healing through Modulation of Hair Follicle Stem Cells	470
An Electromechanical Model-Based Study on the Dosage Effects of Ranolazine in Treating Failing HCM Cardiomyocyte	168
Graph-Based Spatial Proximity of Super-Resolved Protein–Protein Interactions Predicts Cancer Drug Responses in Single Cells	31
Probing the Effects of Chirality on Self-Assembling Peptides: Hydrogel Formation, Degradation, Antigen Release, and Adjuvancy	27
Formins and Arp2/3 Reciprocally Regulate Contact Guidance on Aligned Collagen Fibrils	26
Compressive Forces Shape Tumor–Macrophage Interactions Associated with Immunosuppression in Pancreatic Cancer	23
Causative Role of Anoxic Environment in Bacterial Regulation of Human Intestinal Function	22
FGF-2–Overexpressing Adipose-Derived Stem Cells as a Paracrine Platform for Angiogenesis-Driven Tissue Regeneration	21
Endothelial Cells Stably Infected with Recombinant Kaposi’s Sarcoma-Associated Herpesvirus Display Distinct Viscoelastic and Morphological Properties	19
Relatively Rare Populations of Invasive Cells Drive Progression of Heterogeneous Tumors	17
Multiscale ECM Stiffness Characterization and Quantitative Single-Cell Analysis Reveal ITGA3-Mediated Stiffness-Responsive Subpopulation Dynamics in Papillary Thyroid Carcinoma	17
CRISPR-dCas9 Activation of TSG-6 in MSCs Modulates the Cargo of MSC-Derived Extracellular Vesicles and Attenuates Inflammatory Responses in Human Intervertebral Disc Cells In Vitro	16
Toward a Dual-Axis Model of Microbiome Modulation in Cancer Immunotherapy: Pathobiont Elimination and Functional Ecosystem Restoration	16
Mechanisms and Strategies for Enhancing DNA Nuclear Entry in Gene Delivery	16
Simulation of Somatic Evolution Through the Introduction of Random Mutation to the Rules of Conway’s Game of Life	14
Head-to-Head Comparison of CCN4, DNMT3A, PTPN11, and SPARC as Suppressors of Anti-tumor Immunity	13
Paracrine Signaling by Distinct Adipose Tissue Depots Regulate Fibroblast Mechanobiology and Functional Heterogeneity	13
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease	12
A 3D Human Lymphatic Vessel-on-Chip Reveals the Roles of Interstitial Flow and VEGF-A/C for Lymphatic Sprouting and Discontinuous Junction Formation	12
A Label-Free Colorimetric AuNP-Aptasensor for the Rapid Detection of Vibrio cholerae O139	11
Nanoparticle–Host Interactions: The Impact of Physiological and Pathological Factors on Biodistribution, Immune Processes, and Translational Challenges	11
Based on Medicine, The Now and Future of Large Language Models	11
Sex Differences in Angiogenic Ligand and Receptor Protein Expression During Adipose Tissue Expansion and Regression	10
Publisher Correction: The Intersection of Cancer and Cardiovascular Disease: A Brief Review of Flow and Transport Mechanisms	10
A Conversation on Artificial Intelligence, Chatbots, and Plagiarism in Higher Education	10

THP-1 Macrophages Limit Neutrophil Transendothelial Migration in a Model Infection	10
Caveolin Delivered by Ultrasound-Mediated Microbubble Destruction Prevents Endothelial Cell Proliferation	10
Bio-adhesive Macroporous Hydrogels for In Situ Recruitment and Modulation of Dendritic Cells	9
Investigation of the Therapeutic Effects of Palbociclib Conjugated Magnetic Nanoparticles on Different Types of Breast Cancer Cell Lines	9
Correction: Cardiac Fibrosis: Mechanobiology, Epigenetics, and the Path to Precision Therapy	9
Barrier Function of the Extracellular Matrix in AAV Gene Therapy	9
Magnetoactive, Kirigami-Inspired Hammocks to Probe Lung Epithelial Cell Function	9
Non-linear Characterization of Commercial and Decellularized Hydrogels: Statistical Framework Enhanced by Bayesian Optimization	8
Publisher Correction: Multiscale ECM Stiffness Characterization and Quantitative Single-Cell Analysis Reveal ITGA3-Mediated Stiffness-Responsive Subpopulation Dynamics in Papillary Thyroid Carcinoma	8
A Vascularized Human Organ Chip Reveals SARS-CoV-2 Susceptibility in Developmentally Guided Tissue Maturation	8
The 2025 Young Innovators of Cellular and Molecular Bioengineering	8
siRNA Lipid–Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy	8
Elucidating Mechanotransduction Processes During Magnetomechanical Neuromodulation Mediated by Magnetic Nanodiscs	8
The 2023 Young Innovators of Cellular and Molecular Bioengineering	8
Theoretical and Experimental Studies of the Dynamic Damage of Endothelial Cellular Networks Under Ultrasound Cavitation	7
Extracellular Vesicles (EVs) Mirror Their Source: Comparative Analysis of Bone Marrow-Derived and Adipose-Derived Stem Cells and EVs in Bone Regeneration	7
Hypoxic Preconditioned ADSC Exosomes Enhance Vaginal Wound Healing via Accelerated Keratinocyte Proliferation and Migration Through AKT/HIF‑1α Axis Activation	7
Matrix Stiffness-Mediated DNA Methylation in Endothelial Cells	7
Combining Metformin and Drug-Loaded Kidney-Targeting Micelles for Polycystic Kidney Disease	7
Enhancing Neurological Competence of Nanoencapsulated Cordyceps/Turmeric Extracts in Human Neuroblastoma SH-SY5Y Cells	7
Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport	7
Fetal Bovine Serum Modulates Primary Human Cell Phenotypes, Endothelial Barrier Function, Vasculogenesis, and Angiogenesis in a Sex-Specific Manner	7
Agent-Based Models Help Interpret Patterns of Clinical Drug Resistance by Contextualizing Competition Between Distinct Drug Failure Modes	7
Publisher Correction: Assessing the Relationship Between Bladder Cancer Cell Contractile Phenotypes and Their Invasive Properties	7
G Protein-Coupled Estrogen Receptor Regulates Mesenchymal Stem Cell Mechanotransduction and Differentiation	7
Influence of Hematocrit Level and Integrin αIIbβIII Function on vWF-Mediated Platelet Adhesion and Shear-Induced Platelet Aggregation in a Sudden Expansion	7
Circ_0004585 Facilitates Tumorigenesis of Colorectal Cancer Via Modulating the miR-338-3p/ZFX Axis and Activating the MEK/ERK Pathway	7
Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status	6
Hyaluronic Acid-Coated Melt Electrowritten Scaffolds Promote Myoblast Attachment, Alignment, and Differentiation	6
Enhancing Pluripotency and Adipogenic Differentiation in Human Adipose Tissue-Derived Stem Cells Through miR-302/367 Cluster Overexpression	6
Stiffer-Matrix-Induced PGC-1α Upregulation Enhanced Mitochondrial Biogenesis and Oxidative Stress Resistance in Non-small Cell Lung Cancer	6
Tumor-Targeting Extracellular Vesicles Loaded with siS100A4 for Suppressing Postoperative Breast Cancer Metastasis	6
Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk Using QCM-D	6
Tuning Hydrogel Mechanics and Microstructure to Maximize Extracellular Vesicle Production from Mesenchymal Stem Cells	6
Examining the Effects of Quercetin on Phenotypic Characteristics of Human Mesenchymal Stem Cells	6
Surface-Engineered Mitochondria with Targeting Potential for Endothelial Repair	6
Development of Serum-Free Media for Cryopreservation of Hydrogel Encapsulated Cell-Based Therapeutics	5
Cellular and Molecular Bioengineering: At the Nexus with the Next Editor-in-Chief	5
The 2023 CMBE Young Innovators: ChatGPT Gets the Final Word	5
Intracellular Macromolecular Crowding within Individual Stress Fibers Analyzed by Fluorescence Correlation Spectroscopy	5
Trisomy 21 Alters Cell Proliferation and Migration of iPSC-Derived Cardiomyocytes on Type VI Collagen	5
Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis	5
Myosin II Adjusts Motility Properties and Regulates Force Production Based on Motor Environment	5
Pathological Features of Colorectal Adenocarcinoma Patients Related to MLH1	4
A New Bacterial Chassis for Enhanced Surface Display of Recombinant Proteins	4
A Multicellular Mechanochemical Model to Investigate Tumor Microenvironment Remodeling and Pre-Metastatic Niche Formation	4
Three-Dimensional Fractal Analysis of the Interstitial Cells of Cajal Networks of Gastrointestinal Tissue Specimens	4
Primary Human Cell-Derived Extracellular Matrix from Decellularized Fibroblast Microtissues with Tissue-Dependent Composition and Microstructure	4
Correction: Nanoparticle–Host Interactions: The Impact of Physiological and Pathological Factors on Biodistribution, Immune Processes, and Translational Challenges	4
Mitochondria Clearance Enables Macrophage-Driven Maturation of iPSC-Derived Cardiomyocyte Metabolism	4

Characterization of diffusivity and mechanical properties of polyethylene glycol hydrogel conformal coatings over time for application in beta cell replacement therapy for type 1 diabetes	4
Single-Cell Proliferation Microfluidic Device for High Throughput Investigation of Replicative Potential and Drug Resistance of Cancer Cells	4
Encapsulation of Manganese Porphyrin in Chondroitin Sulfate-A Microparticles for Long Term Reactive Oxygen Species Scavenging	4
Incorporation of ChatGPT and Other Large Language Models into a Graduate Level Computational Bioengineering Course	3
Empowering High-Throughput High-Content Analysis of Microphysiological Models: Open-Source Software for Automated Image Analysis of Microvessel Formation and Cell Invasion	3
Exploring the Causes of Intervertebral Disc Annulus Fibrosus Impairment	3
Altered Caveolin-1 Dynamics Result in Divergent Mineralization Responses in Bone and Vascular Calcification	3
Assessing the Effects of Dasatinib on Mesenchymal Stem/Stromal Cells	3
A Tribute to Rakesh K. Jain on the Occasion of His 75th Birthday	3
Cardiac Fibrosis: Mechanobiology, Epigenetics, and the Path to Precision Therapy	3
Strain Promotes Triple Negative Breast Cancer Proliferation and Migration Via VEGFR-2	3
YIGSR, A Laminin-Derived Peptide, Dictates a Concentration-Dependent Impact on Macrophage Phenotype Response	3
Amelioration of Subglottic Stenosis by Antimicrobial Peptide Eluting Endotracheal Tubes	3
The 2022 Young Innovators of Cellular and Molecular Bioengineering	2
Technological Singularity in Biomedical Science and Engineering	2
Addition of Losartan to Immune Checkpoint Blockade Improves Tumor Control and Neurological Outcomes in Models of NF2-Related Schwannomatosis	2
Role of Lymphatic Endothelium in Vascular Escape of Engineered Human Breast Microtumors	2
Multiomic Integration Reveals Taxonomic Shifts Correlate to Serum Cytokines in an Antibiotics Model of Gut Microbiome Disruption	2
An Integrative Biology Approach to Quantify the Biodistribution of Azidohomoalanine In Vivo	2
Decoupling Mechanical Confinement and Fibrotic Extracellular Matrix Signaling in Vestibular Schwannoma Using Tunable 3D Hydrogels	2
Dynamic Transcriptional Programs During Single NK Cell Killing: Connecting Form to Function in Cellular Immunotherapy	2
Plant Tissue Parenchyma and Vascular Bundles Selectively Regulate Stem Cell Mechanosensing and Differentiation	2
Optogenetic Modulation of Arrhythmia Triggers: Proof-of-Concept from Computational Modeling	2
Correction: Innovation and Entrepreneurship in Promotion and Tenure in Biomedical Engineering	2
Empowering High Throughput Screening of 3D Models: Automated Dispensing of Cervical and Endometrial Cancer Cells	2
Artificial Intelligence, Chatbots, Plagiarism and Basic Honesty: Comment	2
Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells	2
Cell-Extracellular Matrix Feedback Results in Spontaneous Cell Polarization and Heterogeneous Remodeling in 3D Isotropic and Aligned Discrete-Fiber Models of Cell-Mediated Remodeling	2
Light Activates Cdc42-Mediated Needle-Shaped Filopodia Formation via the Integration of Small GTPases	2
The Synergistic Regulation of Lung Cancer Cell Migration by Tensile Stress and Matrix Stiffness	2
Disrupted Sarcomere Reorganization of Cardiomyopathy-Prone Human iPSC-Derived Cardiomyocytes on a Dynamic Mechanical Substrate	2
P300 Modulates Endothelial Mechanotransduction of Fluid Shear Stress	2
TNF-α Preconditioning Promotes a Proangiogenic Phenotype in hiPSC-Derived Vascular Smooth Muscle Cells	2
Uncovering Cellular Interactome Drivers of Immune Checkpoint Inhibitor Response in Advanced Melanoma Patients	2
Contact Guidance Drives Upward Cellular Migration at the Mesoscopic Scale	2
Assessing the Relationship Between Bladder Cancer cell Contractile Phenotypes and their Invasive Properties	2