OOIR: Observatory of International Research

Papers

(The median citation count of Cellular and Molecular Bioengineering is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Acteoside-Loaded Self-Healing Hydrogel Enhances Skin Wound Healing through Modulation of Hair Follicle Stem Cells	458
Causative Role of Anoxic Environment in Bacterial Regulation of Human Intestinal Function	168
An Electromechanical Model-Based Study on the Dosage Effects of Ranolazine in Treating Failing HCM Cardiomyocyte	36
Graph-Based Spatial Proximity of Super-Resolved Protein–Protein Interactions Predicts Cancer Drug Responses in Single Cells	29
Formins and Arp2/3 Reciprocally Regulate Contact Guidance on Aligned Collagen Fibrils	28
FGF-2–Overexpressing Adipose-Derived Stem Cells as a Paracrine Platform for Angiogenesis-Driven Tissue Regeneration	25
Probing the Effects of Chirality on Self-Assembling Peptides: Hydrogel Formation, Degradation, Antigen Release, and Adjuvancy	23
Endothelial Cells Stably Infected with Recombinant Kaposi’s Sarcoma-Associated Herpesvirus Display Distinct Viscoelastic and Morphological Properties	22
CRISPR-dCas9 Activation of TSG-6 in MSCs Modulates the Cargo of MSC-Derived Extracellular Vesicles and Attenuates Inflammatory Responses in Human Intervertebral Disc Cells In Vitro	21
Relatively Rare Populations of Invasive Cells Drive Progression of Heterogeneous Tumors	18
Multiscale ECM Stiffness Characterization and Quantitative Single-Cell Analysis Reveal ITGA3-Mediated Stiffness-Responsive Subpopulation Dynamics in Papillary Thyroid Carcinoma	16
Based on Medicine, The Now and Future of Large Language Models	16
A 3D Human Lymphatic Vessel-on-Chip Reveals the Roles of Interstitial Flow and VEGF-A/C for Lymphatic Sprouting and Discontinuous Junction Formation	16
Simulation of Somatic Evolution Through the Introduction of Random Mutation to the Rules of Conway’s Game of Life	15
Paracrine Signaling by Distinct Adipose Tissue Depots Regulate Fibroblast Mechanobiology and Functional Heterogeneity	14
A Label-Free Colorimetric AuNP-Aptasensor for the Rapid Detection of Vibrio cholerae O139	13
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease	11
Nanoparticle–Host Interactions: The Impact of Physiological and Pathological Factors on Biodistribution, Immune Processes, and Translational Challenges	11
Head-to-Head Comparison of CCN4, DNMT3A, PTPN11, and SPARC as Suppressors of Anti-tumor Immunity	11
Bio-adhesive Macroporous Hydrogels for In Situ Recruitment and Modulation of Dendritic Cells	10
A Conversation on Artificial Intelligence, Chatbots, and Plagiarism in Higher Education	10
Correction: Cardiac Fibrosis: Mechanobiology, Epigenetics, and the Path to Precision Therapy	10
Caveolin Delivered by Ultrasound-Mediated Microbubble Destruction Prevents Endothelial Cell Proliferation	10
Barrier Function of the Extracellular Matrix in AAV Gene Therapy	10
Publisher Correction: The Intersection of Cancer and Cardiovascular Disease: A Brief Review of Flow and Transport Mechanisms	9

Magnetoactive, Kirigami-Inspired Hammocks to Probe Lung Epithelial Cell Function	9
THP-1 Macrophages Limit Neutrophil Transendothelial Migration in a Model Infection	9
Elucidating Mechanotransduction Processes During Magnetomechanical Neuromodulation Mediated by Magnetic Nanodiscs	8
siRNA Lipid–Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy	8
Investigation of the Therapeutic Effects of Palbociclib Conjugated Magnetic Nanoparticles on Different Types of Breast Cancer Cell Lines	8
The 2025 Young Innovators of Cellular and Molecular Bioengineering	8
A Vascularized Human Organ Chip Reveals SARS-CoV-2 Susceptibility in Developmentally Guided Tissue Maturation	8
Publisher Correction: Multiscale ECM Stiffness Characterization and Quantitative Single-Cell Analysis Reveal ITGA3-Mediated Stiffness-Responsive Subpopulation Dynamics in Papillary Thyroid Carcinoma	8
G Protein-Coupled Estrogen Receptor Regulates Mesenchymal Stem Cell Mechanotransduction and Differentiation	7
Hypoxic Preconditioned ADSC Exosomes Enhance Vaginal Wound Healing via Accelerated Keratinocyte Proliferation and Migration Through AKT/HIF‑1α Axis Activation	7
Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport	7
Matrix Stiffness-Mediated DNA Methylation in Endothelial Cells	7
Combining Metformin and Drug-Loaded Kidney-Targeting Micelles for Polycystic Kidney Disease	7
The 2023 Young Innovators of Cellular and Molecular Bioengineering	7
Fetal Bovine Serum Modulates Primary Human Cell Phenotypes, Endothelial Barrier Function, Vasculogenesis, and Angiogenesis in a Sex-Specific Manner	7
Agent-Based Models Help Interpret Patterns of Clinical Drug Resistance by Contextualizing Competition Between Distinct Drug Failure Modes	7
Theoretical and Experimental Studies of the Dynamic Damage of Endothelial Cellular Networks Under Ultrasound Cavitation	7
Circ_0004585 Facilitates Tumorigenesis of Colorectal Cancer Via Modulating the miR-338-3p/ZFX Axis and Activating the MEK/ERK Pathway	7
Influence of Hematocrit Level and Integrin αIIbβIII Function on vWF-Mediated Platelet Adhesion and Shear-Induced Platelet Aggregation in a Sudden Expansion	7
Publisher Correction: Assessing the Relationship Between Bladder Cancer Cell Contractile Phenotypes and Their Invasive Properties	6
Tumor-Targeting Extracellular Vesicles Loaded with siS100A4 for Suppressing Postoperative Breast Cancer Metastasis	6
Stiffer-Matrix-Induced PGC-1α Upregulation Enhanced Mitochondrial Biogenesis and Oxidative Stress Resistance in Non-small Cell Lung Cancer	6
Enhancing Neurological Competence of Nanoencapsulated Cordyceps/Turmeric Extracts in Human Neuroblastoma SH-SY5Y Cells	6
Enhancing Pluripotency and Adipogenic Differentiation in Human Adipose Tissue-Derived Stem Cells Through miR-302/367 Cluster Overexpression	6
Examining the Effects of Quercetin on Phenotypic Characteristics of Human Mesenchymal Stem Cells	6
Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status	6
Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk Using QCM-D	6
Myosin II Adjusts Motility Properties and Regulates Force Production Based on Motor Environment	5
Surface-Engineered Mitochondria with Targeting Potential for Endothelial Repair	5
Pathological Features of Colorectal Adenocarcinoma Patients Related to MLH1	5
Trisomy 21 Alters Cell Proliferation and Migration of iPSC-Derived Cardiomyocytes on Type VI Collagen	5
Hyaluronic Acid-Coated Melt Electrowritten Scaffolds Promote Myoblast Attachment, Alignment, and Differentiation	5
Cellular and Molecular Bioengineering: At the Nexus with the Next Editor-in-Chief	5
The 2023 CMBE Young Innovators: ChatGPT Gets the Final Word	5
High-Density Branched PEGylation for Nanoparticle Drug Delivery	4
Primary Human Cell-Derived Extracellular Matrix from Decellularized Fibroblast Microtissues with Tissue-Dependent Composition and Microstructure	4
A New Bacterial Chassis for Enhanced Surface Display of Recombinant Proteins	4
Characterization of diffusivity and mechanical properties of polyethylene glycol hydrogel conformal coatings over time for application in beta cell replacement therapy for type 1 diabetes	4
Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis	4
Three-Dimensional Fractal Analysis of the Interstitial Cells of Cajal Networks of Gastrointestinal Tissue Specimens	4
Encapsulation of Manganese Porphyrin in Chondroitin Sulfate-A Microparticles for Long Term Reactive Oxygen Species Scavenging	4
Development of Serum-Free Media for Cryopreservation of Hydrogel Encapsulated Cell-Based Therapeutics	4
Intracellular Macromolecular Crowding within Individual Stress Fibers Analyzed by Fluorescence Correlation Spectroscopy	4
Single-Cell Proliferation Microfluidic Device for High Throughput Investigation of Replicative Potential and Drug Resistance of Cancer Cells	4
Incorporation of ChatGPT and Other Large Language Models into a Graduate Level Computational Bioengineering Course	3
Altered Caveolin-1 Dynamics Result in Divergent Mineralization Responses in Bone and Vascular Calcification	3
A Multicellular Mechanochemical Model to Investigate Tumor Microenvironment Remodeling and Pre-Metastatic Niche Formation	3
Amelioration of Subglottic Stenosis by Antimicrobial Peptide Eluting Endotracheal Tubes	3
P300 Modulates Endothelial Mechanotransduction of Fluid Shear Stress	3
Strain Promotes Triple Negative Breast Cancer Proliferation and Migration Via VEGFR-2	3

Exploring the Causes of Intervertebral Disc Annulus Fibrosus Impairment	3
YIGSR, A Laminin-Derived Peptide, Dictates a Concentration-Dependent Impact on Macrophage Phenotype Response	3
Correction: Innovation and Entrepreneurship in Promotion and Tenure in Biomedical Engineering	3
A Tribute to Rakesh K. Jain on the Occasion of His 75th Birthday	3
Correction: Nanoparticle–Host Interactions: The Impact of Physiological and Pathological Factors on Biodistribution, Immune Processes, and Translational Challenges	3
Assessing the Effects of Dasatinib on Mesenchymal Stem/Stromal Cells	3
Empowering High-Throughput High-Content Analysis of Microphysiological Models: Open-Source Software for Automated Image Analysis of Microvessel Formation and Cell Invasion	3
Disrupted Sarcomere Reorganization of Cardiomyopathy-Prone Human iPSC-Derived Cardiomyocytes on a Dynamic Mechanical Substrate	3
Cardiac Fibrosis: Mechanobiology, Epigenetics, and the Path to Precision Therapy	3
Lysophosphatidic Acid (LPA) Receptor Signaling Promotes the Adaptation of Malignant Cellular Functions in Highly Migratory Osteosarcoma Cells Under Hypoxic and Low-Glucose Conditions	2
Multiomic Integration Reveals Taxonomic Shifts Correlate to Serum Cytokines in an Antibiotics Model of Gut Microbiome Disruption	2
Optogenetic Modulation of Arrhythmia Triggers: Proof-of-Concept from Computational Modeling	2
TNF-α Preconditioning Promotes a Proangiogenic Phenotype in hiPSC-Derived Vascular Smooth Muscle Cells	2
Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells	2
Assessing the Relationship Between Bladder Cancer cell Contractile Phenotypes and their Invasive Properties	2
Dynamic Transcriptional Programs During Single NK Cell Killing: Connecting Form to Function in Cellular Immunotherapy	2
Neurogenic Cell Behavior in 3D Culture Enhanced Within a Highly Compliant Synthetic Hydrogel Platform Formed via Competitive Crosslinking	2
Plant Tissue Parenchyma and Vascular Bundles Selectively Regulate Stem Cell Mechanosensing and Differentiation	2
The 2022 Young Innovators of Cellular and Molecular Bioengineering	2
Artificial Intelligence, Chatbots, Plagiarism and Basic Honesty: Comment	2
An Integrative Biology Approach to Quantify the Biodistribution of Azidohomoalanine In Vivo	2
Light Activates Cdc42-Mediated Needle-Shaped Filopodia Formation via the Integration of Small GTPases	2
Empowering High Throughput Screening of 3D Models: Automated Dispensing of Cervical and Endometrial Cancer Cells	2
Role of Lymphatic Endothelium in Vascular Escape of Engineered Human Breast Microtumors	2
Uncovering Cellular Interactome Drivers of Immune Checkpoint Inhibitor Response in Advanced Melanoma Patients	2
Contact Guidance Drives Upward Cellular Migration at the Mesoscopic Scale	2