OOIR: Observatory of International Research

Papers

(The median citation count of Cellular and Molecular Bioengineering is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Graph-Based Spatial Proximity of Super-Resolved Protein–Protein Interactions Predicts Cancer Drug Responses in Single Cells	376
Causative Role of Anoxic Environment in Bacterial Regulation of Human Intestinal Function	154
Probing the Effects of Chirality on Self-Assembling Peptides: Hydrogel Formation, Degradation, Antigen Release, and Adjuvancy	63
Metal Organic Frameworks as Biosensing Materials for COVID-19	32
An Electromechanical Model-Based Study on the Dosage Effects of Ranolazine in Treating Failing HCM Cardiomyocyte	25
Sevoflurane Suppresses the Proliferation, Migration and Invasion of Colorectal Cancer Through Regulating Circ_0000423/miR-525-5p/SGPP1 Network	25
Acteoside-Loaded Self-Healing Hydrogel Enhances Skin Wound Healing through Modulation of Hair Follicle Stem Cells	25
Relatively Rare Populations of Invasive Cells Drive Progression of Heterogeneous Tumors	25
Amelotin Promotes Mineralization and Adhesion in Collagen-Based Systems	19
CRISPR-dCas9 Activation of TSG-6 in MSCs Modulates the Cargo of MSC-Derived Extracellular Vesicles and Attenuates Inflammatory Responses in Human Intervertebral Disc Cells In Vitro	15
Endothelial Cells Stably Infected with Recombinant Kaposi’s Sarcoma-Associated Herpesvirus Display Distinct Viscoelastic and Morphological Properties	15
Mechanical Memory Impairs Adipose-Derived Stem Cell (ASC) Adipogenic Capacity After Long-Term In Vitro Expansion	14
Head-to-Head Comparison of CCN4, DNMT3A, PTPN11, and SPARC as Suppressors of Anti-tumor Immunity	13
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease	13
A Label-Free Colorimetric AuNP-Aptasensor for the Rapid Detection of Vibrio cholerae O139	13
A 3D Human Lymphatic Vessel-on-Chip Reveals the Roles of Interstitial Flow and VEGF-A/C for Lymphatic Sprouting and Discontinuous Junction Formation	13
Simulation of Somatic Evolution Through the Introduction of Random Mutation to the Rules of Conway’s Game of Life	13
Based on Medicine, The Now and Future of Large Language Models	13
A Conversation on Artificial Intelligence, Chatbots, and Plagiarism in Higher Education	12
Caveolin Delivered by Ultrasound-Mediated Microbubble Destruction Prevents Endothelial Cell Proliferation	12
Shear-Mediated Platelet Activation is Accompanied by Unique Alterations in Platelet Release of Lipids	12
THP-1 Macrophages Limit Neutrophil Transendothelial Migration in a Model Infection	11
Magnetoactive, Kirigami-Inspired Hammocks to Probe Lung Epithelial Cell Function	11
Human Atrial Cardiac Microtissues for Chamber-Specific Arrhythmic Risk Assessment	11
Bio-adhesive Macroporous Hydrogels for In Situ Recruitment and Modulation of Dendritic Cells	10

miR-140-5p Overexpression Protects Against Lipopolysaccharide-Induced Necrotizing Pneumonia via Targeting Toll-Like Receptor 4	10
Elucidating Mechanotransduction Processes During Magnetomechanical Neuromodulation Mediated by Magnetic Nanodiscs	10
Investigation of the Therapeutic Effects of Palbociclib Conjugated Magnetic Nanoparticles on Different Types of Breast Cancer Cell Lines	10
siRNA Lipid–Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy	10
Hypoxic Preconditioned ADSC Exosomes Enhance Vaginal Wound Healing via Accelerated Keratinocyte Proliferation and Migration Through AKT/HIF‑1α Axis Activation	9
The 2023 Young Innovators of Cellular and Molecular Bioengineering	9
Influence of Hematocrit Level and Integrin αIIbβIII Function on vWF-Mediated Platelet Adhesion and Shear-Induced Platelet Aggregation in a Sudden Expansion	9
Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport	9
The Role of Rho GTPases During Fibroblast Spreading, Migration, and Myofibroblast Differentiation in 3D Synthetic Fibrous Matrices	9
Matrix Stiffness-Mediated DNA Methylation in Endothelial Cells	8
Agent-Based Models Help Interpret Patterns of Clinical Drug Resistance by Contextualizing Competition Between Distinct Drug Failure Modes	8
Circ_0004585 Facilitates Tumorigenesis of Colorectal Cancer Via Modulating the miR-338-3p/ZFX Axis and Activating the MEK/ERK Pathway	8
Enhancing Neurological Competence of Nanoencapsulated Cordyceps/Turmeric Extracts in Human Neuroblastoma SH-SY5Y Cells	7
Enhancement of Radio-Thermo-Sensitivity of 5-Iodo-2-Deoxyuridine-Loaded Polymeric-Coated Magnetic Nanoparticles Triggers Apoptosis in U87MG Human Glioblastoma Cancer Cell Line	7
A Collagen-Conducting Polymer Composite with Enhanced Chondrogenic Potential	7
Theoretical and Experimental Studies of the Dynamic Damage of Endothelial Cellular Networks Under Ultrasound Cavitation	7
Combining Metformin and Drug-Loaded Kidney-Targeting Micelles for Polycystic Kidney Disease	7
Digestive Enzyme Activity and Protein Degradation in Plasma of Heart Failure Patients	7
Influence of Substrate Stiffness on Barrier Function in an iPSC-Derived In Vitro Blood-Brain Barrier Model	7
Epithelial-to-Mesenchymal Transition Signaling Pathways Responsible for Breast Cancer Metastasis	7
Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status	6
Interplay of Genotype and Substrate Stiffness in Driving the Hypertrophic Cardiomyopathy Phenotype in iPSC-Micro-Heart Muscle Arrays	6
Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk Using QCM-D	6
Site-Specific Cross-Linking of Galectin-1 Homodimers via Poly(ethylene glycol) Bismaleimide	6
Exosomes from Adipose Tissues Derived Mesenchymal Stem Cells Overexpressing MicroRNA-146a Alleviate Diabetic Osteoporosis in Rats	6
The 2021 Young Innovators of Cellular and Molecular Bioengineering	6
Tumor-Targeting Extracellular Vesicles Loaded with siS100A4 for Suppressing Postoperative Breast Cancer Metastasis	6
Stiffer-Matrix-Induced PGC-1α Upregulation Enhanced Mitochondrial Biogenesis and Oxidative Stress Resistance in Non-small Cell Lung Cancer	6
Cellular and Molecular Bioengineering: At the Nexus with the Next Editor-in-Chief	5
Recent Advances in Cellular and Molecular Bioengineering for Building and Translation of Biological Systems	5
Development of Serum-Free Media for Cryopreservation of Hydrogel Encapsulated Cell-Based Therapeutics	5
Myosin II Adjusts Motility Properties and Regulates Force Production Based on Motor Environment	5
High-Density Branched PEGylation for Nanoparticle Drug Delivery	5
Intracellular Macromolecular Crowding within Individual Stress Fibers Analyzed by Fluorescence Correlation Spectroscopy	5
The Combined Influence of Viscoelastic and Adhesive Cues on Fibroblast Spreading and Focal Adhesion Organization	5
Trisomy 21 Alters Cell Proliferation and Migration of iPSC-Derived Cardiomyocytes on Type VI Collagen	5
Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis	5
Pathological Features of Colorectal Adenocarcinoma Patients Related to MLH1	5
Analysis of Regional Variations of the Interstitial Cells of Cajal in the Murine Distal Stomach Informed by Confocal Imaging and Machine Learning Methods	5
The 2023 CMBE Young Innovators: ChatGPT Gets the Final Word	5
Three-Dimensional Fractal Analysis of the Interstitial Cells of Cajal Networks of Gastrointestinal Tissue Specimens	4
A Multicellular Mechanochemical Model to Investigate Tumor Microenvironment Remodeling and Pre-Metastatic Niche Formation	4
A New Bacterial Chassis for Enhanced Surface Display of Recombinant Proteins	4
Primary Human Cell-Derived Extracellular Matrix from Decellularized Fibroblast Microtissues with Tissue-Dependent Composition and Microstructure	4
Encapsulation of Manganese Porphyrin in Chondroitin Sulfate-A Microparticles for Long Term Reactive Oxygen Species Scavenging	4
Crystallization of the Multi-Receptor Tyrosine Kinase Inhibitor Sorafenib for Controlled Long-Term Drug Delivery Following a Single Injection	4
Single-Cell Proliferation Microfluidic Device for High Throughput Investigation of Replicative Potential and Drug Resistance of Cancer Cells	4
Effects of FTY720 on Neural Cell Behavior in Two and Three-Dimensional Culture and in Compression Spinal Cord Injury	3
YIGSR, A Laminin-Derived Peptide, Dictates a Concentration-Dependent Impact on Macrophage Phenotype Response	3
Empowering High-Throughput High-Content Analysis of Microphysiological Models: Open-Source Software for Automated Image Analysis of Microvessel Formation and Cell Invasion	3

Correction: Innovation and Entrepreneurship in Promotion and Tenure in Biomedical Engineering	3
Amelioration of Subglottic Stenosis by Antimicrobial Peptide Eluting Endotracheal Tubes	3
Permeability Properties of an In Vitro Model of the Alveolar Epithelium	3
Incorporation of ChatGPT and Other Large Language Models into a Graduate Level Computational Bioengineering Course	3
Altered Caveolin-1 Dynamics Result in Divergent Mineralization Responses in Bone and Vascular Calcification	3
Exploring the Causes of Intervertebral Disc Annulus Fibrosus Impairment	3
Dose–Response Relationship and Threshold Drug Dosage Identification for a Novel Hybrid Mechanical-Thrombolytic System with an Ultra-Low Dose Patch	3
Assessing the Effects of Dasatinib on Mesenchymal Stem/Stromal Cells	3
SARS-CoV-2 Structural Proteins Exposure Alter Thrombotic and Inflammatory Responses in Human Endothelial Cells	3
Phenytoin Regulates Migration and Osteogenic Differentiation by MAPK Pathway in Human Periodontal Ligament Cells	3
Immune System Effects on Breast Cancer	3
P300 Modulates Endothelial Mechanotransduction of Fluid Shear Stress	3
An Integrative Biology Approach to Quantify the Biodistribution of Azidohomoalanine In Vivo	2
TNF-α Preconditioning Promotes a Proangiogenic Phenotype in hiPSC-Derived Vascular Smooth Muscle Cells	2
Empowering High Throughput Screening of 3D Models: Automated Dispensing of Cervical and Endometrial Cancer Cells	2
The 2022 Young Innovators of Cellular and Molecular Bioengineering	2
Artificial Intelligence, Chatbots, Plagiarism and Basic Honesty: Comment	2
Minimally-Invasive and Efficient Method to Accurately Fit the Bergman Minimal Model to Diabetes Type 2	2
Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays	2
Role of Lymphatic Endothelium in Vascular Escape of Engineered Human Breast Microtumors	2
Plant Tissue Parenchyma and Vascular Bundles Selectively Regulate Stem Cell Mechanosensing and Differentiation	2
Optogenetic Modulation of Arrhythmia Triggers: Proof-of-Concept from Computational Modeling	2
Vesicle-Based Sensors for Extracellular Potassium Detection	2