ChemMedChem

Article	Citations
METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes	104
A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors**	90
Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm‐Associated Infections	90
Cyclobutanes in Small‐Molecule Drug Candidates	78
Porphyrin‐Based Metal−Organic Framework Compounds as Promising Nanomedicines in Photodynamic Therapy	71
Recent Development of Pyrimidine‐Containing Antimicrobial Agents	62
Pectin: A Long‐Neglected Broad‐Spectrum Antibacterial	60
Strategies To Design Selective Histone Deacetylase Inhibitors	57
The Critical Role of Passive Permeability in Designing Successful Drugs	56
Recent Advances in Radiometals for Combined Imaging and Therapy in Cancer	52
Recent Advances in the Prediction of Pharmacokinetics Properties in Drug Design Studies: A Review	49
2‐Isoxazolines: A Synthetic and Medicinal Overview	48
Benzimidazoles in Drug Discovery: A Patent Review	47
Cationic Amphiphilic Peptides: Synthetic Antimicrobial Agents Inspired by Nature	45
Copper: An Intracellular Achilles’ Heel Allowing the Targeting of Epigenetics, Kinase Pathways, and Cell Metabolism in Cancer Therapeutics	44
A Patent Review on the Current Developments of Benzoxazoles in Drug Discovery	42
Coinage Metal N‐Heterocyclic Carbene Complexes: Recent Synthetic Strategies and Medicinal Applications	42
Piperazine, a Key Substructure for Antidepressants: Its Role in Developments and Structure‐Activity Relationships	40
E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity	40
Recent Drug Development and Medicinal Chemistry Approaches for the Treatment of SARS‐CoV‐2 Infection and COVID‐19	37
Cyclic Dipeptide: A Privileged Molecular Scaffold to Derive Structural Diversity and Functional Utility	37
Malaria Pigment Crystals: The Achilles′ Heel of the Malaria Parasite	37
When Virtual Screening Yields Inactive Drugs: Dealing with False Theoretical Friends	37
Do Drug‐likeness Rules Apply to Oral Prodrugs?	36
MPI8 is Potent against SARS‐CoV‐2 by Inhibiting Dually and Selectively the SARS‐CoV‐2 Main Protease and the Host Cathepsin L**	36

Carbon Dots as Drug Delivery Vehicles for Antimicrobial Applications: A Minireview	35
Structure‐Activity Relationships of Benzamides and Isoindolines Designed as SARS‐CoV Protease Inhibitors Effective against SARS‐CoV‐2	35
Fluorinated Cycloalkyl Building Blocks for Drug Discovery	33
1,2,4‐Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase	33
Functional Nanomaterials in Biomedicine: Current Uses and Potential Applications	33
New Antivirals and Antibacterials Based on Silver Nanoparticles	32
Excited State and Reactive Oxygen Species against Cancer and Pathogens: A Review on Sonodynamic and Sono‐Photodynamic Therapy	32
A CaO2@Tannic Acid‐FeIII Nanoconjugate for Enhanced Chemodynamic Tumor Therapy	32
Gold(I) and Gold(III) N‐Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase	32
A Patent Review on FDA‐Approved Antibody‐Drug Conjugates, Their Linkers and Drug Payloads	31
ACE2, the Receptor that Enables Infection by SARS‐CoV‐2: Biochemistry, Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators	31
Mutual Prodrugs of 5‐Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs	29
The Quest for the Best Dual Orexin Receptor Antagonist (Daridorexant) for the Treatment of Insomnia Disorders	29
The Role of Chronic Inflammation in Various Diseases and Anti‐inflammatory Therapies Containing Natural Products	28
Scanning Protein Surfaces with DNA‐Encoded Libraries	28
Mycobacterial Membrane Protein Large 3 (MmpL3) Inhibitors: A Promising Approach to Combat Tuberculosis	28
Drug Repurposing for the SARS‐CoV‐2 Papain‐Like Protease	28
Prioritizing Small Sets of Molecules for Synthesis throughin‐silicoTools: A Comparison of Common Ranking Methods	27
Glycoconjugated Metal Complexes as Cancer Diagnostic and Therapeutic Agents	27
Alternating Cationic‐Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity	27
Emerging Nitric Oxide and Hydrogen Sulfide Releasing Carriers for Skin Wound Healing Therapy	27
Combining PARP Inhibition with Platinum, Ruthenium or Gold Complexes for Cancer Therapy	26
Advances in Nucleoside and Nucleotide Analogues in Tackling Human Immunodeficiency Virus and Hepatitis Virus Infections	26
BODIPY‐Based Photosensitizers as Potential Anticancer and Antibacterial Agents: Role of the Positive Charge and the Heavy Atom Effect	26
An Organogold Compound as Potential Antimicrobial Agent against Drug‐Resistant Bacteria: Initial Mechanistic Insights	26
Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids	26
Effect of Secondary Structure and Side Chain Length of Hydrophobic Amino Acid Residues on the Antimicrobial Activity and Toxicity of 14‐Residue‐Long de novo AMPs	26
Synthesis of Dihydrobenzofuro[3,2‐b]chromenes as Potential 3CLpro Inhibitors of SARS‐CoV‐2: A Molecular Docking and Molecular Dynamics Study	25
Broad‐Spectrum Flavivirus Inhibitors: a Medicinal Chemistry Point of View	25
Comparing the Antileishmanial Activity of Gold(I) and Gold(III) Compounds in L. amazonensis and L. braziliensis in Vitro	25
Acidity and Glutathione Dual‐Responsive Polydopamine‐Coated Organic‐Inorganic Hybrid Hollow Mesoporous Silica Nanoparticles for Controlled Drug Delivery	25
Recent Advances in the Discovery of Multitargeted Tyrosine Kinase Inhibitors as Anticancer Agents	24
Explicit Treatment of Non‐Michaelis‐Menten and Atypical Kinetics in Early Drug Discovery**	24
Amphiphilic Fullerene‐BODIPY Photosensitizers for Targeted Photodynamic Therapy	24
Autophagy‐Dependent Ferroptosis as a Therapeutic Target in Cancer	24
The tale of proteolysis targeting chimeras (PROTACs) for Leucine‐Rich Repeat Kinase 2 (LRRK2)	23
Platinum Cyclooctadiene Complexes with Activity against Gram‐positive Bacteria	23
Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat	23
Peptide‐Mimicking Poly(2‐oxazoline)s Displaying Potent Antimicrobial Properties	23
Synthesis and Biological Evaluation of Pyrazoline and Pyrrolidine‐2,5‐dione Hybrids as Potential Antitumor Agents	22
Native Mass Spectrometry for the Study of PROTAC GNE‐987‐Containing Ternary Complexes	22
Recent Advances on Carbon Monoxide Releasing Molecules for Antibacterial Applications	22
Design and Synthesis of DDR1 Inhibitors with a Desired Pharmacophore Using Deep Generative Models	22
Application of Deep Neural Network Models in Drug Discovery Programs	22
Activatable NIR‐II Fluorescent Probes Applied in Biomedicine: Progress and Perspectives	22
Advancements in the Development of Non‐Nitrogen‐Based Amphiphilic Antiseptics to Overcome Pathogenic Bacterial Resistance	21
Amino Acid Based Antimicrobial Agents – Synthesis and Properties	21
Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design	21
Conjugated Polymers with Aggregation‐Induced Emission Characteristics for Fluorescence Imaging and Photodynamic Therapy	21
Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide‐Based Hybrid Compounds against SARS‐CoV‐2 and Cancer	21

Preparing (Metalla)carboranes for Nanomedicine	21
A Patent Review on SARS Coronavirus Main Protease (3CLpro) Inhibitors	21
Surfing the Third Wave of Ionic Liquids: A Brief Review on the Role of Surface‐Active Ionic Liquids in Drug Development and Delivery	21
Pt(IV) Anticancer Prodrugs – A Tale of Mice and Men	20
Stimuli‐Responsive DNA Origami Nanodevices and Their Biological Applications	20
Bioengineering of Anti‐Inflammatory Natural Products	20
LYTACs: An Emerging Tool for the Degradation of Non‐Cytosolic Proteins	20
Evaluation of Water‐Soluble Mannich Base Prodrugs of 2,3,4,5‐Tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as Multitarget‐Directed Agents for Alzheimer's Disease	20
First‐Generation Bispidine Chelators for 213BiIII Radiopharmaceutical Applications	20
Recent Development of Copper (II) Complexes of Polypyridyl Ligands in Chemotherapy and Photodynamic Therapy	20
Spermine Derivatives of Indole‐3‐carboxylic Acid, Indole‐3‐acetic Acid and Indole‐3‐acrylic Acid as Gram‐Negative Antibiotic Adjuvants	19
Movement of Mitochondria with Mutant DNA through Extracellular Vesicles Helps Cancer Cells Acquire Chemoresistance	19
An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram‐negative Pathogens and Reduced ex vivo Cochleotoxicity	19
Synthesis and Antimicrobial Activity Evaluation of Imidazole‐Fused Imidazo[2,1‐b][1,3,4]thiadiazole Analogues	18
Synthesis and Biological Evaluation of CF3Se‐Substituted α‐Amino Acid Derivatives	18
Theranostics Through the Synergistic Cooperation of Heterometallic Complexes	18
Amino Acid and Peptide‐Based Antiviral Agents	18
New Pyrazine Conjugates: Synthesis, Computational Studies, and Antiviral Properties against SARS‐CoV‐2	18
Gold Drugs with {Au(PPh3)}+ Moiety: Advantages and Medicinal Applications	18
Peptidyl Vinyl Ketone Irreversible Inhibitors of Rhodesain: Modifications of the P2 Fragment	18
Recent Advancement in the Search of Innovative Antiprotozoal Agents Targeting Trypanothione Metabolism	18
Quinoline Hydrazide/Hydrazone Derivatives: Recent Insights on Antibacterial Activity and Mechanism of Action	18
Transition Metal Complexes with Tridentate Schiff Bases (O N O and O N N) Derived from Salicylaldehyde: An Analysis of Their Potential Anticancer Activity	18
Towards the Prediction of Antimicrobial Efficacy for Hydrogen Bonded, Self‐Associating Amphiphiles	17
Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases	17
Highly Phototoxic Transplatin‐Modified Distyryl‐BODIPY Photosensitizers for Photodynamic Therapy	17
Metal‐Based Catalytic Drug Development for Next‐Generation Cancer Therapy	17
4‐Fluorobenzylpiperazine‐Containing Derivatives as Efficient Inhibitors of Mushroom Tyrosinase	17
Purinergic Signaling: Impact of GPCR Structures on Rational Drug Design	17
Contribution of Knoevenagel Condensation Products toward the Development of Anticancer Agents: An Updated Review	16
A “Golden Age” for the discovery of new antileishmanial agents: Current status of leishmanicidal gold complexes and prospective targets beyond the trypanothione system	16
Thiazolidinediones: An In–Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus	16
Desorption Electrospray Ionization Mass Spectrometry Assay for Label‐Free Characterization of SULT2B1b Enzyme Kinetics	16
Oxygenating Biocatalysts for Hydroxyl Functionalisation in Drug Discovery and Development	16
Poly‐l‐lysine Glycoconjugates Inhibit DC‐SIGN‐mediated Attachment of Pandemic Viruses	16
Aggregation‐Induced Emission Luminogens for Mitochondria‐Targeted Cancer Therapy	16
The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition	16
Identification of the FDA‐Approved Drug Pyrvinium as a Small‐Molecule Inhibitor of the PD‐1/PD‐L1 Interaction	16
Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol‐3‐kinase (PI3K): Current and Future Prospects	16
Mechanism toward Turn‐on of Polysaccharide‐Porphyrin Complexes for Fluorescence Probes and Photosensitizers in Photodynamic Therapy in Living Cells	16
Controlling PROTACs with Light	16
Experimental Methods for Evaluating the Bacterial Uptake of Trojan Horse Antibacterials	16
Coumarin‐Thiourea Hybrids Show Potent Carbonic Anhydrase IX and XIII Inhibitory Action	15
Synthesis of Chimeric Thiazolo‐Nootkatone Derivatives as Potent Antimicrobial Agents	15
Structure, Synthesis and Inhibition Mechanism of Nucleoside Analogues as HIV‐1 Reverse Transcriptase Inhibitors (NRTIs)	15
Selective Fragments for the CREBBP Bromodomain Identified from an Encoded Self‐assembly Chemical Library	15
Fragment‐Based Drug Discovery for RNA Targets	15
Cell Penetrating Peptides: Classification, Mechanisms, Methods of Study, and Applications	15
Water‐Soluble Gold(III)–Metformin Complex Alters Mitochondrial Bioenergetics in Breast Cancer Cells	15
Short Photoswitchable Antibacterial Peptides	15
Styryl Group, a Friend or Foe in Medicinal Chemistry	15
Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5 C Degraders	15
The Quest for Orally Available Selective Estrogen Receptor Degraders (SERDs)	15
Structure‐Activity Studies Reveal Scope for Optimisation of Ebselen‐Type Inhibition of SARS‐CoV‐2 Main Protease	15
A Novel Hybrid of Chloroquine and Primaquine Linked by Gold(I): Multitarget and Multiphase Antiplasmodial Agent	15
Mass Spectrometric Assays Reveal Discrepancies in Inhibition Profiles for the SARS‐CoV‐2 Papain‐Like Protease	15
Anticancer Activity of Mannich Bases: A Review of Recent Literature	14
Aliphatic 18F‐Radiofluorination: Recent Advances in the Labeling of Base‐Sensitive Substrates**	14
Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition**	14
Design of Trehalose‐Based Amide/Sulfonamide C‐type Lectin Receptor Signaling Compounds	14
Selected 1,3‐Benzodioxine‐Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors	14
γ‐Non‐Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV	14
Stimulation of Ca2+‐ATPase Transport Activity by a Small‐Molecule Drug	14
Synthesis and Antimicrobial Evaluation of Bis‐morpholine Triazine Quaternary Ammonium Salts	14
Supramolecular Nanodrugs Based on Covalent Assembly of Therapeutic Peptides toward In Vitro Synergistic Anticancer Therapy	14
New Platinum(II) Complexes Affecting Different Biomolecular Targets in Resistant Ovarian Carcinoma Cells	14
Stability and Cell Permeability of Sulfonyl Fluorides in the Design of Lys‐Covalent Antagonists of Protein‐Protein Interactions	14
Prediction of Chameleonic Efficiency	13
Getting a Grip on the Undrugged: Targeting β‐Catenin with Fragment‐Based Methods	13
Machine Learning Guided Discovery of Non‐Hemolytic Membrane Disruptive Anticancer Peptides	13
Effective Oral Administration of an Antitumorigenic Nanoformulated Titanium Complex	13
Modelling and Phenotypic Screening of NAP‐6 and 10‐Cl‐BBQ, AhR Ligands Displaying Selective Breast Cancer Cytotoxicity in Vitro	13
Discovery and Characterization of Multiple Classes of Human CatSper Blockers	13
Turning Donepezil into a Multi‐Target‐Directed Ligand through a Merging Strategy	13
Formaldehyde‐Crosslinked Nontoxic Aβ Monomers to Form Toxic Aβ Dimers and Aggregates: Pathogenicity and Therapeutic Perspectives	13
Next‐Generation Kinase Inhibitors Targeting Specific Biomarkers in Non‐Small Cell Lung Cancer (NSCLC): A Recent Overview	13
A Green Synthesis of Carbene‐Metal‐Amides (CMAs) and Carboline‐Derived CMAs with Potentin vitroandex vivoAnticancer Activity	13
Metal‐Based Aggregation‐Induced Emission Theranostic Systems	13
Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH)	13
Bithiazole Inhibitors of Phosphatidylinositol 4‐Kinase (PI4KIIIβ) as Broad‐Spectrum Antivirals Blocking the Replication of SARS‐CoV‐2, Zika Virus, and Human Rhinoviruses	13

Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes	13
Two Methods, One Goal: Structural Differences between Cocrystallization and Crystal Soaking to Discover Ligand Binding Poses	13
The European Federation for Medicinal Chemistry (EFMC) Best Practice Initiative: Validating Chemical Probes	12
Inspecting the Mechanism of Fragment Hits Binding on SARS‐CoV‐2 Mpro by Using Supervised Molecular Dynamics (SuMD) Simulations	12
SAR Analysis of Heterocyclic Compounds with Monocyclic and Bicyclic Structures as Antifungal Agents	12
Allosteric Molecular Switches in Metabotropic Glutamate Receptors	12
The Triazole Ring as a Privileged Scaffold for Putative Antifungals: Synthesis and Evaluation of a Series of New Analogues	12
Ligand Accessibility Insights to the Dengue Virus NS3‐NS2B Protease Assessed by Long‐Timescale Molecular Dynamics Simulations	12
Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease	12
Chemical and Structural Strategies to Selectively Target mTOR Kinase	12
Red Emissive Carbon Dots Prepared from Polymers as an Efficient Nanocarrier for Coptisine Delivery in vivo and in vitro	12
A Bimetallic Nanozyme with Cascade Effect for Synergistic Therapy of Cancer	12
Synthesis and Biological Evaluation of 10‐Substituted Camptothecin Derivatives with Improved Water Solubility and Activity	12
A Box of Chemistry to Inhibit the MEN1 Tumor Suppressor Gene Promoting Leukemia	12
Anti‐Lung Cancer Activities of 1,2,3‐Triazole Curcumin Derivatives via Regulation of the MAPK/NF‐κB/STAT3 Signaling Pathways	12
Small‐Molecule Inhibitors of Shp2 Phosphatase as Potential Chemotherapeutic Agents for Glioblastoma: A Minireview	12
Design, Synthesis, and Structure‐Activity Relationship Study of Pyrazolones as Potent Inhibitors of Pancreatic Lipase	12
Dual Parasiticidal Activities of Phthalimides: Synthesis and Biological Profile against Trypanosoma cruzi and Plasmodium falciparum	12
Science's Response to CoVID‐19	12
Carborane‐Containing Matrix Metalloprotease (MMP) Ligands as Candidates for Boron Neutron‐Capture Therapy (BNCT)	12
Hybrid Quinazoline 1,3,5‐Triazines as Epidermal Growth Factor Receptor (EGFR) Inhibitors with Anticancer Activity: Design, Synthesis, and Computational Study	12
Development of an Improved Guanidine‐Based Rac1 Inhibitor with in vivo Activity against Non‐Small Cell Lung Cancer	12
Design, Synthesis, in vitro and in silico Characterization of 2‐Quinolone‐L‐alaninate‐1,2,3‐triazoles as Antimicrobial Agents	11
Development of LM98, a Small‐Molecule TEAD Inhibitor Derived from Flufenamic Acid	11
25CN‐NBOH: A Selective Agonist for in vitro and in vivo Investigations of the Serotonin 2A Receptor	11
Organofluorine Hydrazone Derivatives as Multifunctional Anti‐Alzheimer's Agents with CK2 Inhibitory and Antioxidant Features	11
β‐Actin Peptide‐Based Inhibitors of Histidine Methyltransferase SETD3	11
Praziquantel – 50 Years of Research	11
Synthesis of Antiviral Perfluoroalkyl Derivatives of Teicoplanin and Vancomycin	11
Enhancement of CD8+ T‐Cell‐Mediated Tumor Immunotherapy via Magnetic Hyperthermia	11
A Potent Mimetic of the Siglec‐8 Ligand 6’‐Sulfo‐Sialyl Lewisx	11
Evaluation of a Radiolabeled Macrocyclic Peptide as Potential PET Imaging Probe for PD−L1	11
Anticancer Potential of Small‐Molecule Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase	11
7‐Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation	11
Liraglutide‐Loaded Milk Exosomes Lower Blood Glucose When Given by Sublingual Route	11
Clickable Selenylation – a Paradigm for Seleno‐Medicinal Chemistry	11
Microscale Parallel Synthesis of Acylated Aminotriazoles Enabling the Development of Factor XIIa and Thrombin Inhibitors	11
Structure‐Activity Relationships for 5′′ Modifications of 4,5‐Aminoglycoside Antibiotics	11
Using NMR Spectroscopy in the Fragment‐Based Drug Discovery of Small‐Molecule Anticancer Targeted Therapies	11
A Dual Inhibitor of DYRK1A and GSK3β for β‐Cell Proliferation: Aminopyrazine Derivative GNF4877	11
Recent Developments on the Synthesis and Biological Activities of Fused Pyrimidinone Derivatives	11
Anticancer Activity and Mechanism of Action Evaluation of an Acylhydrazone Cu(II) Complex toward Breast Cancer Cells, Spheroids, and Mammospheres	11
The Structures of Gd(III) Chelates Conjugated at the Periphery of 3‐(1’‐Hexyloxy)ethyl‐3‐devinylpyropheophorbide‐a (HPPH) Have a Significant Impact on the Imaging and Therapy of Cancer	11
Synthesis, in vitro Antileishmanial Efficacy and Hit/Lead Identification of Nitrofurantoin‐Triazole Hybrids	11
A Computer‐Driven Scaffold‐Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2‐a]quinoxaline Core	11
A New Potent and Selective Monoamine Oxidase‐B Inhibitor with Extended Conjugation in a Chalcone Framework: 1‐[4‐(Morpholin‐4‐yl)phenyl]‐5‐phenylpenta‐2,4‐dien‐1‐one	11
A Series of Ferulic Acid Amides Reveals Unexpected Peroxiredoxin 1 Inhibitory Activity with in vivo Antidiabetic and Hypolipidemic Effects	11
Design, Synthesis and Evaluation of a Series of 1,5‐Diaryl‐1,2,3‐triazole‐4‐carbohydrazones as Inhibitors of the YAP‐TAZ/TEAD Complex	10
Activating Effect of 3‐Benzylidene Oxindoles on AMPK: From Computer Simulation to High‐Content Screening	10
Aromatic Linkers Unleash the Antiproliferative Potential of 3‐Chloropiperidines Against Pancreatic Cancer Cells	10
Increased in vitro Anti‐HIV Activity of Caffeinium‐Functionalized Polyoxometalates	10
Pentafluoro‐3‐hydroxy‐pent‐2‐en‐1‐ones Potently Inhibit FNT‐Type Lactate Transporters from all Five Human‐Pathogenic Plasmodium Species	10
Tricepyridinium‐inspired QACs yield potent antimicrobials and provide insight into QAC resistance	10
Discovery of Isatin‐Based Carbohydrazones as Potential Dual Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase	10
Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis	10
Point‐of‐Care Pathogen Detection with CRISPR‐based Programmable Nucleic Acid Binding Proteins	10
PROTAC Compatibilities, Degrading Cell‐Surface Receptors, and the Sticky Problem of Finding a Molecular Glue	10
Strategies towards Targeting Gαi/s Proteins: Scanning of Protein‐Protein Interaction Sites To Overcome Inaccessibility	10
From Quinoline to Quinazoline‐Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search	10
Triazolyl‐Functionalized N‐Heterocyclic Carbene Half‐Sandwich Compounds: Coordination Mode, Reactivity and in vitro Anticancer Activity	10
Synergistic and Additive Effects of Menadione in Combination with Antibiotics on Multidrug‐Resistant Staphylococcus aureus: Insights from Structure‐Function Analysis of Naphthoquinones	10
Into the Fray! A Beginner's Guide to Medicinal Chemistry	10
6‐Methyl‐7‐Aryl‐7‐Deazapurine Nucleosides as Anti‐Trypanosoma cruzi Agents: Structure‐Activity Relationship and in vivo Efficacy	10
Virus‐Based Nanoreactors with GALT Activity for Classic Galactosemia Therapy	10
Gold‐Nanoparticle‐Decorated Metal‐Organic Frameworks for Anticancer Therapy	10
Computing Metal‐Binding Proteins for Therapeutic Benefit	10
Natural and Semisynthetic Pentacyclic Triterpenes for Chronic Myeloid Leukemia Therapy: Reality, Challenges and Perspectives	10
Balancing Histone Deacetylase (HDAC) Inhibition and Drug‐likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors	10
N‐Heterocyclic Carbene (NHC) Silver Complexes as Versatile Chemotherapeutic Agents Targeting Human Topoisomerases and Actin	10
Self‐Assembled Porphyrinoids: One‐Component Nanostructured Photomedicines	10
One‐Pot Synthesis and Antiproliferative Activity of Highly Functionalized Pyrazole Derivatives	10
Chemical Reactions Trigger Peptide Self‐Assembly in vivo for Tumor Therapy	9
Synthesis of N‐Aryl‐ and N‐alkyl‐Substituted Imidazolium Silver Complexes: Cytotoxic Screening by Using Human Cell Lines Modelling Acute Myeloid Leukaemia	9
Synthesis of New Tyrosol‐Based Phosphodiester Derivatives: Effect on Amyloid β Aggregation and Metal Chelation Ability	9
Novel Pyridine‐Based Hydroxamates and 2′‐Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity	9
1,2,4‐Triazole‐3‐Thione Analogues with a 2‐Ethylbenzoic Acid at Position 4 as VIM‐type Metallo‐β‐Lactamase Inhibitors	9
Evaluation of 4‐(4‐Fluorobenzyl)piperazin‐1‐yl]‐Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects	9
The Stone Guest: How Does pH Affect Binding Properties of PD‐1/PD‐L1 Inhibitors?	9
Cell‐Penetrating Peptide‐Conjugated BF2‐Oxasmaragdyrins as NIRF Imaging and Photothermal Agents	9
Xanthenylacetic Acid Derivatives Effectively Target Lysophosphatidic Acid Receptor 6 to Inhibit Hepatocellular Carcinoma Cell Growth	9
Complex pBAE Nanoparticle Cell Trafficking: Tracking Both Position and Composition Using Super Resolution Microscopy	9
Engineered Exosomes as a Photosensitizer Delivery Platform for Cancer Photodynamic Therapy	9
Pyrrolo[1,2‐a]quinoxalines: Insulin Mimetics that Exhibit Potent and Selective Inhibition against Protein Tyrosine Phosphatase 1B	9
Targeting the CRD F‐face of Human Galectin‐3 and Allosterically Modulating Glycan Binding by Angiostatic PTX008 and a Structurally Optimized Derivative	9
19F MRI Nanotheranostics for Cancer Management: Progress and Prospects	9
A Series of 2‐((1‐Phenyl‐1H‐imidazol‐5‐yl)methyl)‐1H‐indoles as Indoleamine 2,3‐Dioxygenase 1 (IDO1) Inhibitors	9
Sonodynamic Therapy with Metal Complexes: A New Promise in Cancer Therapy	9
Identification of Adenosine Deaminase Inhibitors by Metal‐binding Pharmacophore Screening	9
A Comprehensive Overview of Structure‐Activity Relationships of Small‐Molecule Splicing Modulators Targeting SF3B1 as Anticancer Agents	9
Scouting around 1,2,3,4‐Tetrahydrochromeno[3,2‐c]pyridin‐10‐ones for Single‐ and Multitarget Ligands Directed towards Relevant Alzheimer's Targets	9
Small‐Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection	9
Vildagliptin‐Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8/9‐Specific Lead	9
Highly Active, Entirely Biobased Antimicrobial Pickering Emulsions	9
Benzimidazole and Benzoxazole Zinc Chelators as Inhibitors of Metallo‐β‐Lactamase NDM‐1	9
Structure‐Activity Relationship and Mode‐Of‐Action Studies Highlight 1‐(4‐Biphenylylmethyl)‐1H‐imidazole‐Derived Small Molecules as Potent CYP121 Inhibitors	9