ChemMedChem

Article	Citations
METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes	116
Cyclobutanes in Small‐Molecule Drug Candidates	108
Therapeutic Strategies To Counteract Antibiotic Resistance in MRSA Biofilm‐Associated Infections	96
A Quick Route to Multiple Highly Potent SARS‐CoV‐2 Main Protease Inhibitors**	94
Strategies To Design Selective Histone Deacetylase Inhibitors	63
Recent Advances in Radiometals for Combined Imaging and Therapy in Cancer	60
Recent Advances in the Prediction of Pharmacokinetics Properties in Drug Design Studies: A Review	57
Benzimidazoles in Drug Discovery: A Patent Review	56
2‐Isoxazolines: A Synthetic and Medicinal Overview	50
Copper: An Intracellular Achilles’ Heel Allowing the Targeting of Epigenetics, Kinase Pathways, and Cell Metabolism in Cancer Therapeutics	46
A Patent Review on the Current Developments of Benzoxazoles in Drug Discovery	45
Piperazine, a Key Substructure for Antidepressants: Its Role in Developments and Structure‐Activity Relationships	45
Coinage Metal N‐Heterocyclic Carbene Complexes: Recent Synthetic Strategies and Medicinal Applications	44
Fluorinated Cycloalkyl Building Blocks for Drug Discovery	43
E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity	43
Gold(I) and Gold(III) N‐Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase	42
Cyclic Dipeptide: A Privileged Molecular Scaffold to Derive Structural Diversity and Functional Utility	42
Do Drug‐likeness Rules Apply to Oral Prodrugs?	42
Functional Nanomaterials in Biomedicine: Current Uses and Potential Applications	39
Recent Drug Development and Medicinal Chemistry Approaches for the Treatment of SARS‐CoV‐2 Infection and COVID‐19	39
When Virtual Screening Yields Inactive Drugs: Dealing with False Theoretical Friends	38
Malaria Pigment Crystals: The Achilles′ Heel of the Malaria Parasite	37
A Patent Review on FDA‐Approved Antibody‐Drug Conjugates, Their Linkers and Drug Payloads	37
Excited State and Reactive Oxygen Species against Cancer and Pathogens: A Review on Sonodynamic and Sono‐Photodynamic Therapy	36
Carbon Dots as Drug Delivery Vehicles for Antimicrobial Applications: A Minireview	36

MPI8 is Potent against SARS‐CoV‐2 by Inhibiting Dually and Selectively the SARS‐CoV‐2 Main Protease and the Host Cathepsin L**	36
The Role of Chronic Inflammation in Various Diseases and Anti‐inflammatory Therapies Containing Natural Products	36
A CaO2@Tannic Acid‐FeIII Nanoconjugate for Enhanced Chemodynamic Tumor Therapy	35
1,2,4‐Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase	35
Mutual Prodrugs of 5‐Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs	33
Mycobacterial Membrane Protein Large 3 (MmpL3) Inhibitors: A Promising Approach to Combat Tuberculosis	32
Emerging Nitric Oxide and Hydrogen Sulfide Releasing Carriers for Skin Wound Healing Therapy	31
Scanning Protein Surfaces with DNA‐Encoded Libraries	30
Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design	30
Prioritizing Small Sets of Molecules for Synthesis throughin‐silicoTools: A Comparison of Common Ranking Methods	30
Advances in Nucleoside and Nucleotide Analogues in Tackling Human Immunodeficiency Virus and Hepatitis Virus Infections	29
Drug Repurposing for the SARS‐CoV‐2 Papain‐Like Protease	28
The tale of proteolysis targeting chimeras (PROTACs) for Leucine‐Rich Repeat Kinase 2 (LRRK2)	27
Platinum Cyclooctadiene Complexes with Activity against Gram‐positive Bacteria	27
Quinoline Hydrazide/Hydrazone Derivatives: Recent Insights on Antibacterial Activity and Mechanism of Action	27
An Organogold Compound as Potential Antimicrobial Agent against Drug‐Resistant Bacteria: Initial Mechanistic Insights	27
Helical Antimicrobial Peptide Foldamers Containing Non‐proteinogenic Amino Acids	26
Synthesis of Dihydrobenzofuro[3,2‐b]chromenes as Potential 3CLpro Inhibitors of SARS‐CoV‐2: A Molecular Docking and Molecular Dynamics Study	26
Autophagy‐Dependent Ferroptosis as a Therapeutic Target in Cancer	26
Synthesis and in vitro Study of Artemisinin/Synthetic Peroxide‐Based Hybrid Compounds against SARS‐CoV‐2 and Cancer	26
Recent Advances in the Discovery of Multitargeted Tyrosine Kinase Inhibitors as Anticancer Agents	26
Transition Metal Complexes with Tridentate Schiff Bases (O N O and O N N) Derived from Salicylaldehyde: An Analysis of Their Potential Anticancer Activity	25
Explicit Treatment of Non‐Michaelis‐Menten and Atypical Kinetics in Early Drug Discovery**	25
Activatable NIR‐II Fluorescent Probes Applied in Biomedicine: Progress and Perspectives	25
Amphiphilic Fullerene‐BODIPY Photosensitizers for Targeted Photodynamic Therapy	25
Recent Development of Copper (II) Complexes of Polypyridyl Ligands in Chemotherapy and Photodynamic Therapy	25
Movement of Mitochondria with Mutant DNA through Extracellular Vesicles Helps Cancer Cells Acquire Chemoresistance	25
Design and Synthesis of DDR1 Inhibitors with a Desired Pharmacophore Using Deep Generative Models	25
Amino Acid Based Antimicrobial Agents – Synthesis and Properties	24
Application of Deep Neural Network Models in Drug Discovery Programs	23
Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat	23
The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition	23
Native Mass Spectrometry for the Study of PROTAC GNE‐987‐Containing Ternary Complexes	23
Recent Advances on Carbon Monoxide Releasing Molecules for Antibacterial Applications	23
LYTACs: An Emerging Tool for the Degradation of Non‐Cytosolic Proteins	23
A Patent Review on SARS Coronavirus Main Protease (3CLpro) Inhibitors	22
Contribution of Knoevenagel Condensation Products toward the Development of Anticancer Agents: An Updated Review	22
Cell Penetrating Peptides: Classification, Mechanisms, Methods of Study, and Applications	22
Surfing the Third Wave of Ionic Liquids: A Brief Review on the Role of Surface‐Active Ionic Liquids in Drug Development and Delivery	22
Bioengineering of Anti‐Inflammatory Natural Products	21
Thiazolidinediones: An In–Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus	21
Amino Acid and Peptide‐Based Antiviral Agents	21
Conjugated Polymers with Aggregation‐Induced Emission Characteristics for Fluorescence Imaging and Photodynamic Therapy	21
Preparing (Metalla)carboranes for Nanomedicine	21
Pt(IV) Anticancer Prodrugs – A Tale of Mice and Men	21
Stimuli‐Responsive DNA Origami Nanodevices and Their Biological Applications	21
Experimental Methods for Evaluating the Bacterial Uptake of Trojan Horse Antibacterials	20
Theranostics Through the Synergistic Cooperation of Heterometallic Complexes	20
Synthesis and Antimicrobial Activity Evaluation of Imidazole‐Fused Imidazo[2,1‐b][1,3,4]thiadiazole Analogues	20
New Pyrazine Conjugates: Synthesis, Computational Studies, and Antiviral Properties against SARS‐CoV‐2	20

Supramolecular Nanodrugs Based on Covalent Assembly of Therapeutic Peptides toward In Vitro Synergistic Anticancer Therapy	20
Metal‐Based Catalytic Drug Development for Next‐Generation Cancer Therapy	20
Evaluation of Water‐Soluble Mannich Base Prodrugs of 2,3,4,5‐Tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as Multitarget‐Directed Agents for Alzheimer's Disease	20
Synthesis and Biological Evaluation of CF3Se‐Substituted α‐Amino Acid Derivatives	19
Highly Phototoxic Transplatin‐Modified Distyryl‐BODIPY Photosensitizers for Photodynamic Therapy	18
Fragment‐Based Drug Discovery for RNA Targets	18
Design, Synthesis, and Structure‐Activity Relationship Study of Pyrazolones as Potent Inhibitors of Pancreatic Lipase	18
Desorption Electrospray Ionization Mass Spectrometry Assay for Label‐Free Characterization of SULT2B1b Enzyme Kinetics	18
A “Golden Age” for the discovery of new antileishmanial agents: Current status of leishmanicidal gold complexes and prospective targets beyond the trypanothione system	18
Identification of the FDA‐Approved Drug Pyrvinium as a Small‐Molecule Inhibitor of the PD‐1/PD‐L1 Interaction	17
Poly‐l‐lysine Glycoconjugates Inhibit DC‐SIGN‐mediated Attachment of Pandemic Viruses	17
Antimalarial and Anticancer Activity Evaluation of Bridged Ozonides, Aminoperoxides, and Tetraoxanes	17
Synthesis of Chimeric Thiazolo‐Nootkatone Derivatives as Potent Antimicrobial Agents	17
Structure‐Activity Studies Reveal Scope for Optimisation of Ebselen‐Type Inhibition of SARS‐CoV‐2 Main Protease	17
Oxygenating Biocatalysts for Hydroxyl Functionalisation in Drug Discovery and Development	17
Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases	17
Water‐Soluble Gold(III)–Metformin Complex Alters Mitochondrial Bioenergetics in Breast Cancer Cells	17
Structure, Synthesis and Inhibition Mechanism of Nucleoside Analogues as HIV‐1 Reverse Transcriptase Inhibitors (NRTIs)	17
Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition**	17
Getting a Grip on the Undrugged: Targeting β‐Catenin with Fragment‐Based Methods	16
Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol‐3‐kinase (PI3K): Current and Future Prospects	16
A Green Synthesis of Carbene‐Metal‐Amides (CMAs) and Carboline‐Derived CMAs with Potentin vitroandex vivoAnticancer Activity	16
Mass Spectrometric Assays Reveal Discrepancies in Inhibition Profiles for the SARS‐CoV‐2 Papain‐Like Protease	16
Design, Synthesis and Evaluation of a Series of 1,5‐Diaryl‐1,2,3‐triazole‐4‐carbohydrazones as Inhibitors of the YAP‐TAZ/TEAD Complex	16
A Novel Hybrid of Chloroquine and Primaquine Linked by Gold(I): Multitarget and Multiphase Antiplasmodial Agent	16
Prediction of Chameleonic Efficiency	16
Anticancer Activity of Mannich Bases: A Review of Recent Literature	16
Styryl Group, a Friend or Foe in Medicinal Chemistry	16
Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5 C Degraders	16
Synthesis and Biological Evaluation of 10‐Substituted Camptothecin Derivatives with Improved Water Solubility and Activity	15
Machine Learning Guided Discovery of Non‐Hemolytic Membrane Disruptive Anticancer Peptides	15
Aliphatic 18F‐Radiofluorination: Recent Advances in the Labeling of Base‐Sensitive Substrates**	15
Science's Response to CoVID‐19	15
Stimulation of Ca2+‐ATPase Transport Activity by a Small‐Molecule Drug	15
Coumarin‐Thiourea Hybrids Show Potent Carbonic Anhydrase IX and XIII Inhibitory Action	15
Synthesis and Antimicrobial Evaluation of Bis‐morpholine Triazine Quaternary Ammonium Salts	14
Bithiazole Inhibitors of Phosphatidylinositol 4‐Kinase (PI4KIIIβ) as Broad‐Spectrum Antivirals Blocking the Replication of SARS‐CoV‐2, Zika Virus, and Human Rhinoviruses	14
Ligand Accessibility Insights to the Dengue Virus NS3‐NS2B Protease Assessed by Long‐Timescale Molecular Dynamics Simulations	14
New Platinum(II) Complexes Affecting Different Biomolecular Targets in Resistant Ovarian Carcinoma Cells	14
Copper and Copper Complexes in Tumor Therapy	14
SAR Analysis of Heterocyclic Compounds with Monocyclic and Bicyclic Structures as Antifungal Agents	14
Next‐Generation Kinase Inhibitors Targeting Specific Biomarkers in Non‐Small Cell Lung Cancer (NSCLC): A Recent Overview	14
γ‐Non‐Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV	14
Synergistic and Additive Effects of Menadione in Combination with Antibiotics on Multidrug‐Resistant Staphylococcus aureus: Insights from Structure‐Function Analysis of Naphthoquinones	14
Metal‐Based Aggregation‐Induced Emission Theranostic Systems	14
Design of Trehalose‐Based Amide/Sulfonamide C‐type Lectin Receptor Signaling Compounds	14
Formaldehyde‐Crosslinked Nontoxic Aβ Monomers to Form Toxic Aβ Dimers and Aggregates: Pathogenicity and Therapeutic Perspectives	14
Hybrid Quinazoline 1,3,5‐Triazines as Epidermal Growth Factor Receptor (EGFR) Inhibitors with Anticancer Activity: Design, Synthesis, and Computational Study	14
Enhancement of CD8+ T‐Cell‐Mediated Tumor Immunotherapy via Magnetic Hyperthermia	14
Development of LM98, a Small‐Molecule TEAD Inhibitor Derived from Flufenamic Acid	14
Phosphonate as a Stable Zinc‐Binding Group for “Pathoblocker” Inhibitors of Clostridial Collagenase H (ColH)	13
A Bimetallic Nanozyme with Cascade Effect for Synergistic Therapy of Cancer	13
Balancing Histone Deacetylase (HDAC) Inhibition and Drug‐likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors	13
Discovery and Characterization of Multiple Classes of Human CatSper Blockers	13
Small‐Molecule Inhibitors of Shp2 Phosphatase as Potential Chemotherapeutic Agents for Glioblastoma: A Minireview	13
19F MRI Nanotheranostics for Cancer Management: Progress and Prospects	13
Recent Developments on the Synthesis and Biological Activities of Fused Pyrimidinone Derivatives	13
Anticancer Activity and Mechanism of Action Evaluation of an Acylhydrazone Cu(II) Complex toward Breast Cancer Cells, Spheroids, and Mammospheres	13
Synthesis, in vitro Antileishmanial Efficacy and Hit/Lead Identification of Nitrofurantoin‐Triazole Hybrids	13
Clickable Selenylation – a Paradigm for Seleno‐Medicinal Chemistry	13
Anticancer Potential of Small‐Molecule Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase	13
Modelling and Phenotypic Screening of NAP‐6 and 10‐Cl‐BBQ, AhR Ligands Displaying Selective Breast Cancer Cytotoxicity in Vitro	13
Organofluorine Hydrazone Derivatives as Multifunctional Anti‐Alzheimer's Agents with CK2 Inhibitory and Antioxidant Features	12
Bioisosterism: 1,2,4‐Oxadiazole Rings	12
Inspecting the Mechanism of Fragment Hits Binding on SARS‐CoV‐2 Mpro by Using Supervised Molecular Dynamics (SuMD) Simulations	12
Using NMR Spectroscopy in the Fragment‐Based Drug Discovery of Small‐Molecule Anticancer Targeted Therapies	12
Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease	12
Benzimidazole and Benzoxazole Zinc Chelators as Inhibitors of Metallo‐β‐Lactamase NDM‐1	12
N‐Heterocyclic Carbene (NHC) Silver Complexes as Versatile Chemotherapeutic Agents Targeting Human Topoisomerases and Actin	12
Chemical and Structural Strategies to Selectively Target mTOR Kinase	12
Structure‐Activity Relationships for 5′′ Modifications of 4,5‐Aminoglycoside Antibiotics	12
Design, Synthesis, in vitro and in silico Characterization of 2‐Quinolone‐L‐alaninate‐1,2,3‐triazoles as Antimicrobial Agents	12
Anti‐Lung Cancer Activities of 1,2,3‐Triazole Curcumin Derivatives via Regulation of the MAPK/NF‐κB/STAT3 Signaling Pathways	12
Development of an Improved Guanidine‐Based Rac1 Inhibitor with in vivo Activity against Non‐Small Cell Lung Cancer	12
Optimization of a Class of Dihydrobenzofurane Analogs toward Orally Efficacious YAP‐TEAD Protein‐Protein Interaction Inhibitors	12
A Box of Chemistry to Inhibit the MEN1 Tumor Suppressor Gene Promoting Leukemia	12
25CN‐NBOH: A Selective Agonist for in vitro and in vivo Investigations of the Serotonin 2A Receptor	12
Self‐Assembled Porphyrinoids: One‐Component Nanostructured Photomedicines	12
One‐Pot Synthesis and Antiproliferative Activity of Highly Functionalized Pyrazole Derivatives	11
Liraglutide‐Loaded Milk Exosomes Lower Blood Glucose When Given by Sublingual Route	11

Copper(I)‐Thiosemicarbazone Complexes with Dual Anticancer and Antiparasitic Activity	11
Strategies towards Targeting Gαi/s Proteins: Scanning of Protein‐Protein Interaction Sites To Overcome Inaccessibility	11
Evaluation of a Radiolabeled Macrocyclic Peptide as Potential PET Imaging Probe for PD−L1	11
Pyrrole: A Decisive Scaffold for the Development of Therapeutic Agents and Structure‐Activity Relationship	11
Point‐of‐Care Pathogen Detection with CRISPR‐based Programmable Nucleic Acid Binding Proteins	11
A Computer‐Driven Scaffold‐Hopping Approach Generating New PTP1B Inhibitors from the Pyrrolo[1,2‐a]quinoxaline Core	11
From Quinoline to Quinazoline‐Based S. aureus NorA Efflux Pump Inhibitors by Coupling a Focused Scaffold Hopping Approach and a Pharmacophore Search	11
Into the Fray! A Beginner's Guide to Medicinal Chemistry	11
β‐Actin Peptide‐Based Inhibitors of Histidine Methyltransferase SETD3	11
Praziquantel – 50 Years of Research	11
Microscale Parallel Synthesis of Acylated Aminotriazoles Enabling the Development of Factor XIIa and Thrombin Inhibitors	11
Natural and Semisynthetic Pentacyclic Triterpenes for Chronic Myeloid Leukemia Therapy: Reality, Challenges and Perspectives	11
Discovery of Isatin‐Based Carbohydrazones as Potential Dual Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase	11
Pentafluoro‐3‐hydroxy‐pent‐2‐en‐1‐ones Potently Inhibit FNT‐Type Lactate Transporters from all Five Human‐Pathogenic Plasmodium Species	10
Nanostructured Copper Surface Kills ESKAPE Pathogens and Viruses in Minutes	10
1,2,4‐Triazole‐3‐Thione Analogues with a 2‐Ethylbenzoic Acid at Position 4 as VIM‐type Metallo‐β‐Lactamase Inhibitors	10
Novel Pyridine‐Based Hydroxamates and 2′‐Aminoanilides as Histone Deacetylase Inhibitors: Biochemical Profile and Anticancer Activity	10
A Synthetic Overview of Benzoxazines and Benzoxazepines as Anticancer Agents	10
Selenocarbamates As a Prodrug‐Based Approach to Carbonic Anhydrase Inhibition	10
6‐Methyl‐7‐Aryl‐7‐Deazapurine Nucleosides as Anti‐Trypanosoma cruzi Agents: Structure‐Activity Relationship and in vivo Efficacy	10
Virus‐Based Nanoreactors with GALT Activity for Classic Galactosemia Therapy	10
Benzofuroxan Derivatives as Potent Agents against Multidrug‐Resistant Mycobacterium tuberculosis	10
Computing Metal‐Binding Proteins for Therapeutic Benefit	10
Increased in vitro Anti‐HIV Activity of Caffeinium‐Functionalized Polyoxometalates	10
Sonodynamic Therapy with Metal Complexes: A New Promise in Cancer Therapy	10
Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis	10
Targeting the CRD F‐face of Human Galectin‐3 and Allosterically Modulating Glycan Binding by Angiostatic PTX008 and a Structurally Optimized Derivative	10
Triazolyl‐Functionalized N‐Heterocyclic Carbene Half‐Sandwich Compounds: Coordination Mode, Reactivity and in vitro Anticancer Activity	10
Design, Synthesis, and Biological Evaluation of (+)‐Camphor‐ and (−)‐Fenchone‐Based Derivatives as Potent Orthopoxvirus Inhibitors	9
A Patent Review on SARS Coronavirus Papain‐Like Protease (PLpro) Inhibitors	9
The Stone Guest: How Does pH Affect Binding Properties of PD‐1/PD‐L1 Inhibitors?	9
RhII‐Catalyzed De‐symmetrization of Ethane‐1,2‐dithiol and Propane‐1,3‐dithiol Yields Metallo‐β‐lactamase Inhibitors	9
Chemical Reactions Trigger Peptide Self‐Assembly in vivo for Tumor Therapy	9
Development of Isatin‐Based Schiff Bases Targeting VEGFR‐2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies	9
Engineered Exosomes as a Photosensitizer Delivery Platform for Cancer Photodynamic Therapy	9
Small‐Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection	9
Evaluation of 4‐(4‐Fluorobenzyl)piperazin‐1‐yl]‐Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects	9
Developments in the Discovery and Design of Protein Kinase D Inhibitors	9
A Series of 2‐((1‐Phenyl‐1H‐imidazol‐5‐yl)methyl)‐1H‐indoles as Indoleamine 2,3‐Dioxygenase 1 (IDO1) Inhibitors	9
Stereoselective Access to Antimelanoma Agents by Hybridization and Dimerization of Dihydroartemisinin and Artesunic acid	9
Xanthenylacetic Acid Derivatives Effectively Target Lysophosphatidic Acid Receptor 6 to Inhibit Hepatocellular Carcinoma Cell Growth	9
Thiazolidinone‐Heterocycle Frameworks: A Concise Review of Their Pharmacological Significance	9
Synthesis of New Tyrosol‐Based Phosphodiester Derivatives: Effect on Amyloid β Aggregation and Metal Chelation Ability	9
Synthesis and Biological Evaluation of Dantrolene‐Like Hydrazide and Hydrazone Analogues as Multitarget Agents for Neurodegenerative Diseases	9
Vildagliptin‐Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8/9‐Specific Lead	9
Highly Active, Entirely Biobased Antimicrobial Pickering Emulsions	9
Structure‐Activity Relationship and Mode‐Of‐Action Studies Highlight 1‐(4‐Biphenylylmethyl)‐1H‐imidazole‐Derived Small Molecules as Potent CYP121 Inhibitors	9
Inhibition of Amyloid Protein Aggregation Using Selected Peptidomimetics	9
Multidrug Idebenone/Naproxen Co‐loaded Aspasomes for Significant in vivo Anti‐inflammatory Activity	9
Complex pBAE Nanoparticle Cell Trafficking: Tracking Both Position and Composition Using Super Resolution Microscopy	9
Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation	9
Systematic Assessment of Fragment Identification for Multitarget Drug Design	8
Action of Dipeptidyl Peptidase‐4 Inhibitors on SARS‐CoV‐2 Main Protease	8
Biochemical Screening of Potent Zika Virus Protease Inhibitors	8
Borcalein: a Carborane‐Based Analogue of Baicalein with 12‐Lipoxygenase‐Independent Toxicity	8
Plasmid DNA‐Based Bioluminescence‐Activated System for Photodynamic Therapy in Cancer Treatment	8
Calcification‐Based Cancer Diagnosis and Therapy	8
An Integrated in silico Approach and in vitro Study for the Discovery of Small‐Molecule USP7 Inhibitors as Potential Cancer Therapies	8
Radical Scavenging Potential of the Phenothiazine Scaffold: A Computational Analysis	8
Drug‐Derived Surface‐Active Ionic Liquids: A Cost‐Effective Way To Expressively Increase the Blood‐Stage Antimalarial Activity of Primaquine	8
Recent Advances in Dual BRD4‐Kinase Inhibitors Based on Polypharmacology	8
Light‐Controllable Binary Switch Activation of CAR T Cells	8
Not Every Hit‐Identification Technique Works on 1‐Deoxy‐d‐Xylulose 5‐Phosphate Synthase (DXPS): Making the Most of a Virtual Screening Campaign	8
Evaluation of Anticancer Activity of 1,3‐Oxazol‐4‐ylphosphonium Salts in Vitro	8
Design, Synthesis, and in vitro Evaluation of Tubulin‐Targeting Dibenzothiazines with Antiproliferative Activity as a Novel Heterocycle Building Block	8
Discovery of GPR183 Agonists Based on an Antagonist Scaffold	8
Synthesis of Isocryptolepine‐Triazole Adducts and Evaluation of Their Cytotoxic Activity	8
DprE1 Inhibitors: Enduring Aspirations for Future Antituberculosis Drug Discovery	8
Amyloid‐β Inspired Short Peptide Amphiphile Facilitates Synthesis of Silver Nanoparticles as Potential Antibacterial Agents	8
Inhibition Studies on Carbonic Anhydrase Isoforms I, II, IX, and XII with a Series of Sulfaguanidines	8
2′,3′‐Cyclic GMP‐AMP Dinucleotides for STING‐Mediated Immune Modulation: Principles, Immunotherapeutic Potential, and Synthesis	8
Transition Metal Complexes as Antimalarial Agents: A Review	8
Synthesis and Assessment of Fused β‐Carboline Derivatives as Kappa Opioid Receptor Agonists	8
All Ag Nanoparticles Are Not the Same: Covalent Interactions between Ag Nanoparticles and Nitrile Groups Help Combat Drug‐ and Ag‐Resistant Bacteria	8
Click Chemistry and Targeted Degradation: A Winning Combination for Medicinal Chemists?	8
Rational Optimization of Dihydropyrimidinone‐Quinoline Hybrids as Plasmodium falciparum Glutathione Reductase Inhibitors	8
Anticancer Activities of Tetrasubstituted Imidazole‐Pyrimidine‐Sulfonamide Hybrids as Inhibitors of EGFR Mutants	8
Novel Phenylmethylenecyclohexenone Derivatives as Potent TrxR Inhibitors Display High Antiproliferative Activity and Induce ROS, Apoptosis, and DNA Damage	8
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery	8
Hexafluoroisopropyl Carbamates as Selective MAGL and Dual MAGL/FAAH Inhibitors: Biochemical and Physicochemical Properties	8
An Anti‐inflammatory Fe3O4‐Porphyrin Nanohybrid Capable of Apoptosis through Upregulation of p21 Kinase Inhibitor Having Immunoprotective Properties under Anticancer PDT Conditio	8
Synthesis, Characterization, and in vivo Distribution of Intracellular Delivered Macrolide Short‐Chain Fatty Acid Derivatives	7
Synthesis and Biological Evaluation of Dithiobisacetamides as Novel Urease Inhibitors	7
Rational Design and Synthesis of Selective PRMT4 Inhibitors: A New Chemotype for Development of Cancer Therapeutics**	7
Novel Phenyl‐Based Bis‐quaternary Ammonium Compounds as Broad‐Spectrum Biocides	7
Erlotinib‐Modified BODIPY Photosensitizers for Targeted Photodynamic Therapy	7
Dinitrophenol‐Hyaluronan Conjugates as Multivalent Antibody‐Recruiting Glycopolymers for Targeted Cancer Immunotherapy	7
Synthesis and Structure‐Activity Relationship of Xenocoumacin 1 and Analogues as Inhibitors of Ribosomal Protein Synthesis	7
In vitro and Microbiological Assay of Functionalized Hybrid Nanomaterials To Validate Their Efficacy in Nanotheranostics: A Combined Spectroscopic and Computational Study	7
Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library	7
Total Syntheses and Chemical Biology Studies of Hymeglusin and Fusarilactone A, Novel Circumventors of β‐Lactam Drug Resistance in Methicillin‐Resistant Staphylococcus aureus	7
Engineered s‐Triazine‐Based Dendrimer‐Honokiol Conjugates as Targeted MMP‐2/9 Inhibitors for Halting Hepatocellular Carcinoma	7
Newer Non‐ionic A2B2‐Type Enzyme‐Responsive Amphiphiles for Drug Delivery	7
The Impact of Activity‐Based Protein Profiling in Malaria Drug Discovery	7
Improving Strategies in the Development of Protein‐Downregulation‐Based Antiandrogens	7