ChemMedChem

Article	Citations
Chimeric Amphiphilic Disinfectants: Quaternary Ammonium/Quaternary Phosphonium Hybrid Structures	116
Front Cover: A Single Second Shell Amino Acid Determines Affinity and Kinetics of Linagliptin Binding to Type 4 Dipeptidyl Peptidase and Fibroblast Activation Protein (ChemMedChem 4/2021)	108
Discovery of Antimetastatic Chiral Ionone Alkaloid Derivatives Targeting HIF‐1α/VEGF/VEGFR2 Pathway	63
Exploration of Ligand‐receptor Binding and Mechanisms for Alginate Reduction and Phenotype Reversion by Mucoid Pseudomonas aeruginosa	60
Front Cover: Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1 (ChemMedChem 15/2023)	57
Front Cover: Are Two Riboses Better Than One? The Case of the Recognition and Activation of Adenosine Receptors (ChemMedChem 14/2023)	56
Front Cover: Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity (ChemMedChem 5/2023)	46
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One‐Pot Synthesis of Coumarin–Indomethacin Hybrids as COX‐2 Targeting Probes for Cancer Imaging	44
Front Cover: Developing Low Molecular Weight PET and SPECT Imaging Agents (ChemMedChem 15/2024)	43
Sulfonamide Bioisosteres of Niclosamide Enhance Antibacterial Activity of Colistin and Bacitracin	43
Anti‐Sporothrix Activity of Novel Copper‐Itraconazole Complexes	42
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Intracellular Delivery of Antisense Oligonucleotides by Tri‐Branched Cyclic Disulfide Units	42
In Silico Prediction of ERRα Agonists Based on Combined Features and Stacking Ensemble Method	39
Cover Feature: The IMS Library: from IN‐Stock to Virtual (ChemMedChem 20/2024)	39
Synthesis of trans‐Fused 3,6‐Anhydro Hexofuranose Frameworks via Catalytic Hydrogenolysis Triggered Debenzylative Intramolecular Acetalation	38
CORRIGENDUM: Carboranes as Potent Phenyl Mimetics: A Comparative Study on the Reversal of ABCG2‐Mediated Drug Resistance by Carboranylquinazolines and Their Organic Isosteres	37
Improving Affinity while Reducing Kidney Uptake of CXCR4‐Targeting Radioligands Derived from the Endogenous Antagonist EPI‐X4	37
N‐Heterocyclic Carbene (NHC) Silver Complexes as Versatile Chemotherapeutic Agents Targeting Human Topoisomerases and Actin	36
Importance of Co‐operative Hydrogen Bonding in the Apramycin‐Ribosomal Decoding A‐Site Interaction	36
Improving Strategies in the Development of Protein‐Downregulation‐Based Antiandrogens	36
Strategies To Design Selective Histone Deacetylase Inhibitors	36
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Front Cover: Fragment‐Based Design, Synthesis, and Characterization of Aminoisoindole‐Derived Furin Inhibitors (ChemMedChem 9/2024)	35
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Lysyl Oxidases as Targets for Cancer Therapy and Diagnostic Imaging	31
Chalcone‐Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering	31
Scouting Different Phosphodiesterase 4 Inhibitor Chemotypes in Silico To Guide the Design of Anti‐inflammatory/Antioxidant Agents	30
A Critical Study on Acylating and Covalent Reversible Fragment Inhibitors of SARS‐CoV‐2 Main Protease Targeting the S1 Site with Pyridine	30
Coordinated Axial Ligand and d‐π Conjugated Network Makes the Difference: Engineered 2D Mn‐Based Antioxidase Mimic for Enhancing Stem Cell Protection	29
Strategies toward Metal‐Free Carbon Monoxide Prodrugs: An Update	28
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Front Cover: Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors (ChemMedChem 6/2023)	27
Front Cover: Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein (ChemMedChem 10/2023)	26
Front Cover: Terpyridine Glycoconjugates and Their Metal Complexes: Antiproliferative Activity and Proteasome Inhibition (ChemMedChem 7/2023)	26
Kinase Degraders, Activators, and Inhibitors: Highlights and Synthesis Routes to the Chemical Probes on opnMe.com, Part 1	26
Phenotypic Discovery of SB1501, an Anti‐obesity Agent, through Modulating Mitochondrial Activity	25
Design and Synthesis of 1,3‐Diynes as Potent Antifungal Agents against Aspergillus fumigatus	25
Cancer‐Mitochondria Dual‐Targeting Glycol/Ferrocenium‐Based Polydopamine Nanoparticles for Synergistic Photothermal and Photodynamic Therapy	25
Structural Development of Salicylanilide‐Based SPAK Inhibitors as Candidate Antihypertensive Agents	25
Front Cover: Bithiazole Inhibitors of Phosphatidylinositol 4‐Kinase (PI4KIIIβ) as Broad‐Spectrum Antivirals Blocking the Replication of SARS‐CoV‐2, Zika Virus, and Human Rhinoviruses (ChemMedChem 23/2	25
Terpyridine Glycoconjugates and Their Metal Complexes: Antiproliferative Activity and Proteasome Inhibition	25
Prospects and Challenges of Developing Plant‐Derived Snake Antivenin Natural Products: A Focus on West Africa	24
Synthesis of a Bifunctional Cross‐Bridged Chelating Agent, Peptide Conjugation, and Comparison of 68Ga Labeling and Complex Stability Characteristics with Established Chelators	23
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Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library	23
A Small Molecule with Bridged Carbonyl and Tri‐fluoro‐aceto‐phenone Groups Impedes Microtubule Dynamics and Subsequently Triggers Cancer Cell Apoptosis	23
Front Cover: Covalent Allosteric Inhibitors of Akt Generated Using a Click Fragment Approach (ChemMedChem 10/2022)	23
Successful Drug Discovery, Volume 5. Edited by János Fischer, Christian Klein, and Wayne E. Childers	23
Russell Mechanism‐Mediated Cancer Therapy: A Minireview	22
A Structure‐Activity Relationship Study of Amino Acid Derivatives of Pterostilbene Analogues Toward Human Breast Cancer	22
A Single‐Atom Nanozyme Cascade for Selective Tumor‐Microenvironment‐Responsive Nanocatalytic Therapy	22
Chemical Derivatization Leads to the Discovery Of Novel Analogs of Azotochelin, a Natural Siderophore, as Promising Anticancer Agents	22
Front Cover: Design, Synthesis, and Antiviral Activity of the Thiazole Positional Isomers of a Potent HIV‐1 Entry Inhibitor NBD‐14270 (ChemMedChem 22/2022)	21
Anticancer Activity and Mechanism of Action Evaluation of an Acylhydrazone Cu(II) Complex toward Breast Cancer Cells, Spheroids, and Mammospheres	21
Front Cover: Prodrug Approach to Exploit (S)‐Alanine Amide as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors (ChemMedChem 17/2024)	21
Inhibitors of Aspartate Transcarbamoylase Inhibit Mycobacterium tuberculosis Growth	21
Front Cover: Development of Fluorophosphoramidate as a Biocompatibly Transformable Functional Group and its Application as a Phosphate Prodrug for Nucleoside Analogs (ChemMedChem 17/2022)	21
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Organofluorine Hydrazone Derivatives as Multifunctional Anti‐Alzheimer's Agents with CK2 Inhibitory and Antioxidant Features	20
Novel Phenyl‐Based Bis‐quaternary Ammonium Compounds as Broad‐Spectrum Biocides	20
Front Cover: Targeted Redox Balancing through Pulmonary Nanomedicine Delivery Reverses Oxidative Stress Induced Lung Inflammation (ChemMedChem 11/2024)	20
Front Cover: Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti‐SARS‐CoV‐2 Activity (ChemMedChem 5/2022)	19
Interaction of a Triantennary Quinoline Glycoconjugate with the Asialoglycoprotein Receptor	18
Medicinal Chemistry for Practitioners. Edited by Jie Jack Li	18
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CYP3A4 Catalyzes the Rearrangement of the Dual Orexin Receptor Antagonist Daridorexant to 4‐Hydroxypiperidinol Metabolites	17
Front Cover: r‐BRICS – A Revised BRICS Module That Breaks Ring Structures and Carbon Chains (ChemMedChem 4/2024)	17
Front Cover: Stabilizing Pseudouridimycin: Synthesis, RNA Polymerase Inhibitory Activity, and Antibacterial Activity of Dipeptide‐Modified Analogues (ChemMedChem 1/2024)	17
Mass Spectrometric Assays Reveal Discrepancies in Inhibition Profiles for the SARS‐CoV‐2 Papain‐Like Protease	17
The Impact of Activity‐Based Protein Profiling in Malaria Drug Discovery	17

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Decoration of Squalenoyl‐Gemcitabine Nanoparticles with Squalenyl‐Hydroxybisphosphonate for the Treatment of Bone Tumors	17
Sphaeropsidin A C15–C16 Cross‐Metathesis Analogues with Potent Anticancer Activity	17
Conception and Evaluation of Fluorescent Phosphine‐Gold Complexes: From Synthesis to in vivo Investigations	17
An Active Member of the EFMC: The Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society**	17
Discovery of Isatin‐Based Carbohydrazones as Potential Dual Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase	16
Synthesis and in vitro Metabolic Stability of Sterically Shielded Antimycobacterial Phenylalanine Amides	16
Front Cover: Design Principles for Balancing Lipophilicity and Permeability in beyond Rule of 5 Space (ChemMedChem 5/2024) (ChemMedChem 5/2024)	16
In vitro and Microbiological Assay of Functionalized Hybrid Nanomaterials To Validate Their Efficacy in Nanotheranostics: A Combined Spectroscopic and Computational Study	16
Development of Kinase‐Centric Drugs: A Computational Perspective	16
Incorporation of Trifluoromethyltriazoline in the Side Chain of 4‐Aminoquinolines: Synthesis and Evaluation as Antiplasmodial Agents	16
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Moving out of CF3‐Land: Synthesis, Receptor Affinity, and in silico Studies of NK1 Receptor Ligands Containing a Pentafluorosulfanyl (SF5) Group	15
Front Cover: The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform‐Selective Inhibitors (ChemMedChem 18/2022)	15
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Front Cover: (R)‐PFI‐2 Analogues as Substrates and Inhibitors of Histone Lysine Methyltransferase SETD7 (ChemMedChem 23/2023)	15
Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity	14
Front Cover: Mechanism toward Turn‐on of Polysaccharide‐Porphyrin Complexes for Fluorescence Probes and Photosensitizers in Photodynamic Therapy in Living Cells (5/2021)	14
Rational Design and Synthesis of Selective PRMT4 Inhibitors: A New Chemotype for Development of Cancer Therapeutics**	14
Synthesis and Biological Activity of 2‐Benzo[b]thienyl and 2‐Bithienyl Amidino‐Substituted Benzothiazole and Benzimidazole Derivatives	14
Adsorption to the Surface of Hemozoin Crystals: Structure‐Based Design and Synthesis of Amino‐Phenoxazine β‐Hematin Inhibitors	14
Fragment‐Based Drug Discovery for RNA Targets	14
Naturally Occurring and Widespread Resistance to Bioactive Natural Products	14
Preparing (Metalla)carboranes for Nanomedicine	14
DprE1 Inhibitors: Enduring Aspirations for Future Antituberculosis Drug Discovery	14
Synthesis, Characterization and in vitro Anticancer Evaluation of 5‐Sulfinyl(sulfonyl)‐4‐arylsulfonyl‐Substituted 1,3‐Oxazoles	14
Thiazolidinediones: An In–Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus	14
Design, Synthesis, and Bioactivity Evaluations of 3‐Methylenechroman‐2‐one Derivatives as Thioredoxin Reductase (TrxR) Inhibitors	14
Carborane‐Based Tebufelone Analogs and Their Biological Evaluation In Vitro	14
Calcification‐Based Cancer Diagnosis and Therapy	14
Evaluation of Rhodanine Indolinones as AANAT Inhibitors	14
Front Cover: Structural Development of Androgen Receptor Antagonists Using Phenylferrocene Framework as a Hydrophobic Pharmacophore (ChemMedChem 6/2024)	13
Mapping the Melatonin Receptor. 8. Selective MT2 Agonists Derived from 5,6‐Dihydroindolo[2,1‐a]isoquinolines and Related Systems	13
Design and Synthesis of Novel 2‐Acetamido, 6‐Carboxamide Substituted Benzothiazoles as Potential BRAFV600E Inhibitors – In vitro Evaluation of their Antiproliferative Activity	13
Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction–Optimization Strategy Applied to Paullones	13
Development of Benzimidazole‐Substituted Spirocyclopropyl Oxindole Derivatives as Cytotoxic Agents: Tubulin Polymerization Inhibition and Apoptosis Inducing Studies	13
Assessment of CYP2C9 Structural Models for Site of Metabolism Prediction	13
Prodrugs of the Archetypal Dynamin Inhibitor Bis‐T‐22	13
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class	13
C9‐Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α‐Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration	13
Design, Synthesis and Biological Evaluation of Novel Anticancer Amidinourea Analogues via Unexpected 1,3,5‐Triazin‐2‐one Ring Opening	13
Promoting GAINs (Give Attention to Limitations in Assays) over PAINs Alerts: no PAINS, more GAINs	12
An Investigation on Linker Modifications of Cyanoguanidine‐Based P2X7 Receptor Antagonists	12
Computer‐Aided Search for 5‐Arylideneimidazolone Anticancer Agents Able To Overcome ABCB1‐Based Multidrug Resistance	12
Synthesis and Cell Growth Inhibitory Activity of Six Non‐glycosaminoglycan‐Type Heparin‐Analogue Trisaccharides	12
Exploring Viral Interference Using Peptides: Molecular Determinants of HIV‐1 Inhibition by a Peptide Derived from Human Pegivirus‐1 Envelope Protein E2	12
Repurposing Anticancer Drugs To Tackle Malaria	12
Sialic Acid 4‐N‐Piperazine and Piperidine Derivatives Bind with High Affinity to the P. mirabilis Sialic Acid Sodium Solute Symporter	12
Hepatic‐Targeted Nano‐enzyme with Resveratrol Loading for Precise Relief of Nonalcoholic Steatohepatitis	12
Design and Synthesis of Fsp3‐Enriched Spirocyclic‐Based Biological Screening Compound Arrays via DOS Strategies and Their NNMT Inhibition Profiling	12
Novel Octahedral Nickel (II) Complex with Flexible Piperazinyl Moiety Exhibits Potent Cytotoxic Effect Along with Anti‐Migratory and Anti‐Metastatic Effect on Human Cancer Cells	12
RNA oligomers at atomic resolution containing 1‐methylpseudouridine, an essential building block of mRNA vaccines	12
RhII‐Catalyzed De‐symmetrization of Ethane‐1,2‐dithiol and Propane‐1,3‐dithiol Yields Metallo‐β‐lactamase Inhibitors	12
MPI8 is Potent against SARS‐CoV‐2 by Inhibiting Dually and Selectively the SARS‐CoV‐2 Main Protease and the Host Cathepsin L**	12
Cyclodextrin Dimers Functionalized with Biotin as Nanocapsules for Active Doxorubicin Delivery Against MCF‐7 Breast Cell Line	11
Halogen‐Dance‐Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2‐Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases	11
Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4	11
Current Approaches and Strategies Applied in First‐in‐class Drug Discovery	11
Autophagy‐Mediated Targeted Protein Degradation	11
Performance of Ir(III)‐Based Anticancer Agents in the Treatment of Cisplatin‐Resistant Cancer Cells	11
Straightforward Synthesis of DFO* ‐ An Octadentate Chelator for Zirconium‐89	11
Phosphate‐Containing Glycolipids: A Review on Synthesis and Bioactivity	11
Isopeptidic Desferrioxamine Analogues: The Role of Hydroxamate Spacing for Chelation of Zr4+	11
Evaluation of a Radioiodinated G‐Quadruplex Binder in Cervical Cancer Models	11
hERG Optimization of Benzofuro−Pyridine and Pyrazino−Indole Derivatives as MCHR1 Antagonists	11
Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1	11
Native State Stabilization of Amyloidogenic Proteins by Kinetic Stabilizers: Inhibition of Protein Aggregation and Clinical Relevance	11
Aniquinazoline B, a Fungal Natural Product, Activates the μ‐Opioid Receptor	11
Synthesis and Carbonic Anhydrase I, II, IX, and XII Inhibition Studies with a Series of Cyclic Sulfonyl Guanidines	11
Mycobacterial Membrane Protein Large 3 (MmpL3) Inhibitors: A Promising Approach to Combat Tuberculosis	10
Development of LpxH Inhibitors Chelating the Active Site Dimanganese Metal Cluster of LpxH	10
Newer Non‐ionic A2B2‐Type Enzyme‐Responsive Amphiphiles for Drug Delivery	10
Promising Antifungal and Antibacterial Agents Based on 5‐Aryl‐2,2′‐bipyridines and Their Heteroligand Salicylate Metal Complexes: Synthesis, Bioevaluation, Molecular Docking	10
Advances in the Analysis of Pharmaceuticals by Using Graphene‐Based Sensors	10
Sonodynamic Therapy with Metal Complexes: A New Promise in Cancer Therapy	10
WaterMap‐Guided Structure‐Based Virtual Screening for Acetylcholinesterase Inhibitors	10
Cyclopentadienyl‐Based Anticancer Drugs: Improvement of Cytotoxic Activity through Functionalisation of the π Ligand	10
Biomolecular Interactions of Cytotoxic Ruthenium Compounds with Thiosemicarbazone or Benzothiazole Schiff Base Chelates	10
Mesoporous Polydopamine‐Based Nanovehicles as a Versatile Drug Loading Platform to Enable Tumor‐Sufficient Synergistic Therapy	10
Effect of meso Positioned Substituents on the Stability and Photodynamic Activity of Lipid‐Membrane‐Incorporated Porphyrin Derivatives	10

1‐Indanone and 1,3‐indandione Derivatives as Ligands for Misfolded α‐Synuclein Aggregates	10
Metal‐Based Aggregation‐Induced Emission Theranostic Systems	10
Ideas Behind the Tryptophan‐Mediated Petasis Reaction (TMPR) Concept for Peptide Stapling	9
Application of Phosphoramidate ProTide Technology for the Synthesis of 5’‐mRNA Cap Analogs Modified on the Exocyclic Amine Group	9
Synthesis of Triphenylethylene‐Naphthalimide Conjugates as topoisomerase‐IIα inhibitor and HSA binder	9
Prediction of Chameleonic Efficiency	9
Discovery of Antitumor Active Peptides Derived from Peroxiredoxin 5	9
A Promising Approach to Target Colorectal Cancer Using Hybrid Triarylmethanes	9
Molecular Nanoarchitectonics of Natural Photosensitizers and Their Derivatives Nanostructures for Improved Photodynamic Therapy	9
The Hydrazine Moiety in the Synthesis of Modified Nucleosides and Nucleotides	9
Structure‐Activity Relationship and Mode‐Of‐Action Studies Highlight 1‐(4‐Biphenylylmethyl)‐1H‐imidazole‐Derived Small Molecules as Potent CYP121 Inhibitors	9
Design, Synthesis, and in Vitro Evaluation of 4‐(4‐Hydroxyphenyl)piperazine‐Based Compounds Targeting Tyrosinase	9
Anticancer Activities of Tetrasubstituted Imidazole‐Pyrimidine‐Sulfonamide Hybrids as Inhibitors of EGFR Mutants	9
Glass Box and Black Box Machine Learning Approaches to Exploit Compositional Descriptors of Molecules in Drug Discovery and Aid the Medicinal Chemist	9
Inhibitory Effect of Salicin on Staphylococcus aureus Coagulase	9
Fluorinated High‐Valent Sn(IV) Porphyrins Show Remarkable Photodynamic Activity in Cancer Cells	9
Chemical Design Strategy of Ionizable Lipids for In Vivo mRNA Delivery	9
Late‐Stage Diversification of Pyrazoles as Antileishmanial Agents	9
Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5 C Degraders	9
Self‐Assembled Porphyrinoids: One‐Component Nanostructured Photomedicines	9
Generation of Molecular Counterfactuals for Explainable Machine Learning Based on Core‐Substituent Recombination	9
Developing Dynamic Structure‐Based Pharmacophore and ML‐Trained QSAR Models for the Discovery of Novel Resistance‐Free RET Tyrosine Kinase Inhibitors Through Extensive MD Trajectories and NRI Analysis	9
Anthraquinone‐Based Ligands as MNase Inhibitors: Insights from Inhibition Studies and Generation of a Payload Nanocarrier for Potential Anti‐MRSA Therapy	8
Seeing in the Future – a Perspective on Combining Light with Chemical Biology Approaches to Treat Retinal Pathologies	8
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Gaucher Disease: A Glance from a Medicinal Chemistry Perspective	8
Dual Centrifugation‐Based Screening for pH‐Responsive Liposomes	8
Adenine Modification at C7 as a Viable Strategy to Potentiate the Antimalarial Activity of Quinolones	8
Emergence of Quantum Dots as Innovative Tools for Early Diagnosis and Advanced Treatment of Breast Cancer	8
Structure‐Based Virtual Screening and in vitro and in vivo Analyses Revealed Potent Methyltransferase G9a Inhibitors as Prospective Anti‐Alzheimer's Agents	8
Design, Synthesis and Biological Evaluation of Histone Deacetylase Inhibitors Based on Pyrrolo[2,3‐d]pyrimidine and Pyrrolo[2,3‐b]pyridine Scaffolds	8
Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design	8
α‐Triazolylboronic Acids: A Novel Scaffold to Target FLT3 in AML	8
The Role of Protein Disulfide Isomerase Inhibitors in Cancer Therapy	8
Insight into Stabilization of G‐Quadruplex in c‐MYC Region with Phenanthroimidazoisoindol‐Acrylates and their Binding Behaviour towards Human Serum Albumin	8
Effects of Structural Variations on Antibacterial Properties for Conjugated Diynes Generated through Glaser Hay Couplings	8
Into the Fray! A Beginner's Guide to Medicinal Chemistry	8
Excited State and Reactive Oxygen Species against Cancer and Pathogens: A Review on Sonodynamic and Sono‐Photodynamic Therapy	8
The Role of Chronic Inflammation in Various Diseases and Anti‐inflammatory Therapies Containing Natural Products	8
Corrigendum: Discovery and Characterization of Multiple Classes of Human CatSper Blockers	8
Recent Development of Copper (II) Complexes of Polypyridyl Ligands in Chemotherapy and Photodynamic Therapy	8
Front Cover: Carborane Conjugates with Ibuprofen, Fenoprofen and Flurbiprofen: Synthesis, Characterization, COX Inhibition Potential and In Vitro Activity (ChemMedChem 1/2025)	8
Diastereoselective Cascade Double Michael Addition to Access Bridged Coumarins, Oxindoles and Spirooxindoles: A Sustainable Strategy for Synthesis of Anticancer Molecules	8
Design of Dual EP2/EP4 Antagonists through Scaffold Merging of Selective Inhibitors	8
CORRIGENDUM: α‐Triazolylboronic Acids: A Novel Scaffold to Target FLT3 in AML	8
Discovery of Quinoline‐Derived Trifluoromethyl Alcohols as Antiepileptic and Analgesic Agents That Block Sodium Channels	8
Flavonoid‐Quinoxaline Hybrid Compounds as Cathepsin Inhibitors Against Fascioliasis	8
Copper and Copper Complexes in Tumor Therapy	8
From DC18 to MR07: A Metabolically Stable 4,4′‐Oxybisbenzoyl Amide as a Low‐Nanomolar Growth Inhibitor of P. falciparum	8
Synthesis of Isocryptolepine‐Triazole Adducts and Evaluation of Their Cytotoxic Activity	8
Covalent Fragment Screening Identifies Rgl2 RalGEF Cysteine for Targeted Covalent Inhibition of Ral GTPase Activation	8
Promising Therapeutic Approach for SARS‐CoV‐2 Infections by Using a Rutin‐Based Combination Therapy	7
Breaking Barriers in Photothermal Tumor Therapy: A Cascade of Strain‐Engineered Nanozyme in Action	7
Optimization of Ketobenzothiazole‐Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication	7
Carbon‐13 Hyperpolarization of α‐Ketocarboxylates with Parahydrogen in Reversible Exchange	7
Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside	7
Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR‐1) Reveals Inverse NOR‐1 Agonists	7
European Medicinal Chemistry Leaders in Industry (EMCL) – On the Status and Future of Medicinal Chemistry Research in Europe**	7
Front Cover: Identification of ß‐Glucocerebrosidase Activators for Glucosylceramide hydrolysis (ChemMedChem 7/2024)	7
Nanoradiopharmaceuticals: An Attractive Concept in Oncotherapy	7
Selectfluor‐Mediated Chlorination and Fluorination of Arenes: Late‐Stage Functionalization of APIs and Its Biological Effects	7
An Organogold Compound as Potential Antimicrobial Agent against Drug‐Resistant Bacteria: Initial Mechanistic Insights	7
Highlights from the Lowlands: Early Career Researchers Shine at Medicinal Chemistry Frontiers 2024	7
Front Cover: Towards Imaging Pt Chemoresistance Using Gd(III)‐Pt(II) Theranostic MR Contrast Agents (ChemMedChem 24/2021)	7
Corrigendum: Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development	7
Biocatalytic Amino Acid Functionalisation	7
Insights into the Overcoming EGFRDel19/T790M/C797S Mutation: A Perspective on the 2‐Aryl‐4‐aminothienopyrimidine Backbone	7
C7‐Halomethylene/methyl‐C3‐thiophenyl‐spirocyclic‐β‐lactams: Synthesis, X‐ray Analysis, Antimicrobial Evaluation, Cytotoxicity Profile and Molecular Docking Interactions	7
Targeting N‐Methyl‐lysine Histone Demethylase KDM4 in Cancer: Natural Products Inhibitors as a Driving Force for Epigenetic Drug Discovery	7
Expanding the Variety of Pyridinium‐Based bis‐QACs with Antimicrobial Properties: Investigation into Linker Structure‐Activity Correlation.	7
Compound Interaction Screen on a Photoactivatable Cellulose Membrane (CISCM) Identifies Drug Targets	7
A Series of 2‐((1‐Phenyl‐1H‐imidazol‐5‐yl)methyl)‐1H‐indoles as Indoleamine 2,3‐Dioxygenase 1 (IDO1) Inhibitors	7
Accelerating BRPF1b hit identification with BioPhysical and Active Learning Screening (BioPALS)	7
Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase	7
Synthesis of Fluorinated Imidazole[4,5f][1,10]phenanthroline Derivatives as Potential Inhibitors of Liver Cancer Cell Proliferation by Inducing Apoptosis via DNA Damage	7
Evaluation of a Radiolabeled Macrocyclic Peptide as Potential PET Imaging Probe for PD−L1	7
DOTAP Modified Formulations of Aminoacid Based Cationic Liposomes for Improved Gene Delivery and Cell Viability	7
Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies	7
New Indole‐Based Phenylthiazolyl‐2,4‐dihydropyrazolones as Tubulin polymerization inhibitors: Multicomponent Synthesis, Cytotoxicity Evaluation, and in silico Studies	7
Diagnosis and Therapeutic Strategies Based on Nucleic Acid Aptamers Selected against Pseudomonas aeruginosa: The Challenge of Cystic Fibrosis	7
Exploring Derivatives of Quinolizidine Alkaloid Sophoridine in the Design and Biological Mechanistic Evaluation of Histone Deacetylase Inhibitors against Triple‐Negative Breast Cancer	7
Thiazole‐Based IL‐17 Inhibitors Discovered by Scaffold Morphing	7
“Cofactors” for Natural Products	7
Screening for New Inhibitors of Glycine Transporter 1 and 2 by Means of MS Binding Assays	7
Design, Synthesis and Biological Activity of New Amides Derived from 3‐Benzhydryl and 3‐sec‐Butyl‐2,5‐dioxo‐pyrrolidin‐1‐yl‐acetic Acid	7
Synthesis, Binding Affinity Analysis, and 18F Radiosynthesis of Small‐Molecular‐Weight HIF‐1α‐Binding Compounds	7
The Spanish Society of Medicinal Chemistry: Promoting Pharmaceutical R&D in Spain since 1977	7
A Structure‐Activity Relationship Study of Bimodal BODIPY‐Labeled PSMA‐Targeting Bioconjugates	7
Design and Synthesis of Tetrahydropyrrolo[3,4‐c]pyrazole Sigma‐1 Receptor Ligands	7
Synthesis and Anticancer Evaluation of Disubstituted Benzimidazoles via One‐Pot Telescopic Grinding Approach	7
Discovery of Anti‐tubercular Analogues of Bedaquiline with Modified A‐, B‐ and C‐Ring Subunits	6
Rational design and virtual screening identify mimetics of the RXR agonist valerenic acid	6
Discovery of a Dual‐Target Inhibitor of CDK7 and HDAC1 That Induces Apoptosis and Inhibits Migration in Colorectal Cancer**	6
Design, Synthesis, and Optimization of Indole Acetic Acid Derivatives as Potent and Selective CRTH2 Receptor Antagonists: Discovery of ACT‐774312	6
Blood Components as Carriers for Small‐Molecule Platinum Anticancer Drugs	6