OOIR: Observatory of International Research

Papers

(The H4-Index of ChemMedChem is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Late‐Stage Diversification of Pyrazoles as Antileishmanial Agents	148
Substituted Benzylidene‐3‐Oxo‐3,4‐Dihydro‐2 H ‐Benzo[ b ][1,4]thiazine‐6‐Carboxylic Acid Analogs as Dynami	92
Generation of Molecular Counterfactuals for Explainable Machine Learning Based on Core‐Substituent Recombination	89
	81
Nicorandil Repurposing in Orofacial Pain: Preclinical Findings in Adult Zebrafish	79
	75
Front Cover: Design Principles for Balancing Lipophilicity and Permeability in beyond Rule of 5 Space (ChemMedChem 5/2024) (ChemMedChem 5/2024)	62
Scouting Different Phosphodiesterase 4 Inhibitor Chemotypes in Silico To Guide the Design of Anti‐inflammatory/Antioxidant Agents	60
	55
Front Cover: (ChemMedChem 12/2025)	51
Anti‐Sporothrix Activity of Novel Copper‐Itraconazole Complexes	51
An Active Member of the EFMC: The Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society**	48
API‐ILs Ionic Adducts: Solubility and Surface Activity Properties—En Route to New Paradigm in Drug Development	45
Insights into the Overcoming EGFR^{Del19/T790M/C797S} Mutation: A Perspective on the 2‐Aryl‐4‐aminothienopyrimidine Backbone	42
Optimization of Ketobenzothiazole‐Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication	38
Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4	37
C9‐Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α‐Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration	37
Phosphate‐Containing Glycolipids: A Review on Synthesis and Bioactivity	35
Fluorescence‐Based Detection of Methionine for Noninvasive Cancer Diagnosis Using Cu–Sn Bimetallic Nanoclusters	35
“Cofactors” for Natural Products	34
Cyclin‐Dependent Kinase 11: Cellular Functions and Potential Therapeutic Applications	33
The 5′ Cap Epitranscriptome and Beyond: Natural and Engineered 5′ Cap Modifications for Optimizing mRNA Therapeutics and Functional Studies	32
Metalloids: Semi as Metals yet Full of Antimicrobial Potential	31
Therapeutic Exosomes for Rare Cancers: Advances and Clinical Translation	31
Redox Disruption Induced by Saquayamycin B1 Promotes Cytotoxicity in Resistant Melanoma Cells	30

Front Cover: Functional Proteomics of Quinazolin‐4‐One Derivatives Targeting the Proteasome (ChemMedChem 2/2026)	30
CYP3A4 Catalyzes the Rearrangement of the Dual Orexin Receptor Antagonist Daridorexant to 4‐Hydroxypiperidinol Metabolites	29
Fluorinated High‐Valent Sn(IV) Porphyrins Show Remarkable Photodynamic Activity in Cancer Cells	28
Importance of Co‐operative Hydrogen Bonding in the Apramycin‐Ribosomal Decoding A‐Site Interaction	28