Theranostics

Article	Citations
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	653
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	486
A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy	396
Biosynthetic gas vesicles as a novel ultrasound contrast agent for diagnosing and treating myocardial infarction	389
A low molecular weight multifunctional theranostic molecule for the treatment of prostate cancer	231
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	228
Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	223
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	221
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	193
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	182
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	173
Noninvasive closed-loop acoustic brain-computer interface for seizure control	172
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	166
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	165
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy	163
Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity — Introducing High NET Affinity PET Probe 18F-AF78	163
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	158
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	153
ASIC1a Induces Excessive Mitophagy and PANoptosis of Chondrocyte by the Inhibition of SIRT3 Mitochondrial Translocation	149
Recent progress of nano-drugs in neutron capture therapy	146
The LMIT: Light-mediated minimally-invasive theranostics in oncology	146
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype	142
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	141
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold	138
5-Aminolevulinate improves metabolic recovery and cell survival of the liver following cold preservation	136

Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms	134
Targeted delivery of anti-miRNA21 sensitizes PD-L1high tumor to immunotherapy by promoting immunogenic cell death	129
FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts	128
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	126
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model	125
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	122
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m6A/YTHDF1-mediated enhancement on ATG3 stability	122
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	120
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	117
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	113
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	113
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	112
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	111
Dual-targeted magnetic mesoporous silica nanoparticles reduce brain amyloid-β burden via depolymerization and intestinal metabolism	108
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	108
High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease	105
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	103
Emerging microfluidics-enabled platforms for osteoarthritis management: from benchtop to bedside	102
Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal stromal cells after hypoxic-ischaemic brain damage	101
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	100
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	98
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	97
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	97
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	97
The emerging role of Piezo1 in the musculoskeletal system and disease	96
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	95
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	95
Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial: Erratum	92
A Transferrin-Conjugated Hollow Nanoplatform for Redox-Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions: Erratum	92
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α: Erratum	92
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	90
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	89
Optic chiasmatic potential by endoscopically implanted skull base microinvasive biosensor: a brain-machine interface approach for anterior visual pathway assessment	89
Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection	89
Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease	88
Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum	88
TRIM4 enhances small-molecule-induced neddylated-degradation of CORO1A for triple negative breast cancer therapy	84
Topical application of TAK1 inhibitor encapsulated by gelatin particle alleviates corneal neovascularization	83
Targeting formyl peptide receptor 2 to suppress neuroinflammation in neuromyelitis optica spectrum disorder	83
Unlocking the dual role of LSD1 in tumor immunity: innate and adaptive pathways	82
NAD+-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice	81
The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer	81
Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation	81
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration	80
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	80
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	79
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	79
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy	78
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy	78
TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response	78

Kir6.1/K-ATP channel in astrocytes is an essential negative modulator of astrocytic pyroptosis in mouse model of depression	77
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	77
The first abdominal aortic aneurysm organoid model replicates complex microenvironment for in vitro disease study	76
Intermittent fasting reprograms the brain proteome to prevent synaptic degeneration and cognitive impairment in vascular dementia	76
Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation	76
Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies	75
Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer	75
SERS Tags for Biomedical Detection and Bioimaging	75
First-in-human study of an optimized, potential kit-type, SSTR antagonist 68Ga-DATA5m-LM4 in patients with metastatic neuroendocrine tumors	75
The role of lipid metabolic reprogramming in tumor microenvironment	74
Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development	72
Platelet membrane decorated exosomes enhance targeting efficacy and therapeutic index to alleviate arterial restenosis	72
IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasis	72
Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury	70
Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma	70
Supercharging CAR-T cells through transcriptional and epigenetic armoring	70
Identification of early invisible acute ischemic stroke in non-contrast computed tomography using two-stage deep-learning model	70
Revolutionizing cancer treatment: the emerging potential and potential challenges of in vivo self-processed CAR cell therapy	70
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution	69
Extracellular vesicles: catching the light of intercellular communication in fibrotic liver diseases	69
Wound microenvironment-responsive glucose consumption and hydrogen peroxide generation synergistic with azithromycin for diabetic wounds healing	68
CBX4 suppresses CD8+ T cell antitumor immunity by reprogramming glycolytic metabolism	68
How to improve photodynamic therapy-induced antitumor immunity for cancer treatment?	67
Re-engineering the inner surface of ferritin nanocage enables dual drug payloads for synergistic tumor therapy	67
Pre-metastatic niche: from revealing the molecular and cellular mechanisms to the clinical applications in breast cancer metastasis	67
Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication	67
Multiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing	67
Cathelicidin-related antimicrobial peptide protects against enteric pathogen-accelerated type 1 diabetes in mice	66
Engineering of donor-acceptor-donor curcumin analogues as near-infrared fluorescent probes for in vivo imaging of amyloid-β species	66
Noninvasive DWI tracking of hiPSCs differentiation into RTECs in AKI recovery via the KSP promoter-mediated AQP1 strategy	66
Integrated analysis of circulating immune cellular and soluble mediators reveals specific COVID19 signatures at hospital admission with utility for prediction of clinical outcomes	66
Promotion of Cx26 mutants located in TM4 region for membrane translocation successfully rescued hearing loss	65
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription	65
Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma	64
Intratumoral synthesis of transformable metal-phenolic nanoaggregates with enhanced tumor penetration and retention for photothermal immunotherapy	64
Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury	63
Cardiomyocyte-derived small extracellular vesicle: a new mechanism driving diabetic cardiac fibrosis and cardiomyopathy	62
Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound	62
FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC	62
Single-shot multiparametric MRI for separating T2 effects from dynamic glucose-enhanced contrast	62
Reduction-responsive RNAi nanoplatform for enhanced cancer sonoimmunotherapy via dual inhibition of mitophagy and Nrf2 pathways	61
Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration	61
Morphine- and foot shock-responsive neuronal ensembles in the VTA possess different connectivity and biased GPCR signaling pathway	61
Essential role of IL-17 in acute exacerbation of pulmonary fibrosis induced by non-typeable Haemophilus influenzae	61
Mechanisms and novel therapeutic roles of bitter taste receptors in diseases	60
Single-nucleus RNA sequencing and spatial transcriptomics reveal an immunosuppressive tumor microenvironment related to metastatic dissemination during pancreatic cancer liver metastasis	60
Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging	59
Repopulated retinal microglia promote Müller glia reprogramming and preserve visual function in retinal degenerative mice	59
Extracellular vehicles-mediated Twsit1 transferred from tumor cells to brain induces depressive-like behaviors via neuronal morphogenesis	59
5-aminolevulinate and CHIL3/CHI3L1 treatment amid ischemia aids liver metabolism and reduces ischemia-reperfusion injury	58
Secreted Clever-1 modulates T cell responses and impacts cancer immunotherapy efficacy	58
Honokiol enhances the sensitivity of cetuximab in KRASG13D mutant colorectal cancer through destroying SNX3-retromer complex	57
Oncofetal TRIM71 drives liver cancer carcinogenesis through remodeling CEBPA-mediated serine/glycine metabolism	56
High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo Magnetic Particle Imaging	56
iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway	56
The biphasic role of Hspb1 on ferroptotic cell death in Parkinson's disease	55
Restoration of CPT1A-mediated fatty acid oxidation in mesothelial cells protects against peritoneal fibrosis	55
Activated molecular probes for enzyme recognition and detection	54
Ferroptosis at the nexus of metabolism and metabolic diseases	54
The metallic compound promotes primordial follicle activation and ameliorates fertility deficits in aged mice	54
DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury	54
The orchestration of cell-cycle reentry and ribosome biogenesis network is critical for cardiac repair	54
Artificial intelligence-enhanced retinal imaging as a biomarker for systemic diseases	53
Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2	53
Avoiding the self-nucleation interference: a pH-regulated gold in situ growth strategy to enable ultrasensitive immunochromatographic diagnostics	53
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke	53
Dysadherin awakens mechanical forces and promotes colorectal cancer progression	52
Building consensus on the application of organoid-based drug sensitivity testing in cancer precision medicine and drug development	52
Engineered mesenchymal stem cell-derived extracellular vesicles: A state-of-the-art multifunctional weapon against Alzheimer's disease	52
Multiple regulatory mechanisms, functions and therapeutic potential of chaperone-mediated autophagy	52
[161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC: preliminary dosimetry results and intra-individual head-to-head comparison to [177Lu]Lu-PSMA-617	51
PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain	51
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents	51
Processed microalgae: green gold for tissue regeneration and repair	51
Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer's disease	51
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy	51
Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo	51
Environment-responsive dendrobium polysaccharide hydrogel embedding manganese microsphere as a post-operative adjuvant to boost cascaded immune cycle against melanoma	51
Co-delivery of 5-fluorouracil and miRNA-34a mimics by host-guest self-assembly nanocarriers for efficacious targeted therapy in colorectal cancer patient-derived tumor xenografts: Erratum	50
Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles	50

Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists	50
Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies	50
βKlotho is identified as a target for theranostics in non-small cell lung cancer: Erratum	50
Focused ultrasound activates voltage-gated calcium channels through depolarizing TRPC1 sodium currents in kidney and skeletal muscle	50
What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake	49
DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo	49
Magnetic sculpture-like tumor cell vaccines enable targeted in situ immune activation and potent antitumor effects	49
Intranasal delivery of imaging agents to the brain	49
SUMOylation of SARS-CoV-2 spike protein is a key target for broad-spectrum antiviral therapy	48
18F-5-fluoro-aminosuberic acid PET/CT imaging of oxidative-stress features during the formation of DEN-induced rat hepatocellular carcinoma	48
A versatile nanoplatform with excellent biofilm permeability and spatiotemporal ROS regulation for peri-implantitis treatment	48
A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation	48
PINCH-1 promotes IGF-1 receptor expression and skin cancer progression through inhibition of the GRB10-NEDD4 complex	48
X-ray stimulates NQO1-dependent cascade reactions to induce strong immunogenicity for MRI-guided cancer radio-chemodynamic-immunotherapy	48
Bioactive metal-protein matrix for promoting MRSA infection wound therapy through bioenergy-induced angiogenesis	48
Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK inhibitors	47
Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway: Erratum	47
Loss of DDX24 inhibits lung cancer progression by stimulating IKBKG splicing-mediated autophagy	47
Naturally derived hydrogel with antioxidant, angiogenesis and photothermal effect to accelerate infected diabetic wound healing and reduce scar formation	47
Biofilm-disrupting heterojunction microneedles: dual ROS amplification and glucose deprivation for accelerated diabetic wound healing	47
Intranasal delivery of mitochondrial protein humanin rescues cell death and promotes mitochondrial function in Parkinson's disease	47
Knocking out USP7 attenuates cardiac fibrosis and endothelial-to-mesenchymal transition by destabilizing SMAD3 in mice with heart failure with preserved ejection fraction	47
m6A-induced lncDBET promotes the malignant progression of bladder cancer through FABP5-mediated lipid metabolism	47
A H2S-activated NIR-II imaging probe for precise diagnosis and pathological evaluation of colorectal tumor	47
CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells	47
Advances and challenges in decellularized adipose tissue based composite hydrogels for adipose tissue regeneration: a review over the last fifteen years	47
Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice	46
Mesenchymal stem cell-derived extracellular vesicles targeting irradiated intestine exert therapeutic effects	46
Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice	46
Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease	46
Renal tubular epithelial-derived follistatin-like 1 protects against UUO-induced renal fibrosis in mice via inhibiting NF-κB-mediated epithelial inflammation	46
PET imaging of CXCR4 expression using [18F]AlF-NOTA-QHY-04 for hematologic malignancy and solid tumors	46
Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications	45
DNA aptamers inhibit SARS-CoV-2 spike-protein binding to hACE2 by an RBD- independent or dependent approach	45
Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment	44
Advances in subpopulation separation and detection of extracellular vesicles: for liquid biopsy and downstream research	44
Extracellular matrix proteins refine microenvironments for pancreatic organogenesis from induced pluripotent stem cell differentiation	44
A novel ferroptosis inhibitor, Thonningianin A, improves Alzheimer's disease by activating GPX4	44
An MMP-degradable and conductive hydrogel to stabilize HIF-1α for recovering cardiac functions	44
An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation	43
Multifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bo	43
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosis	43
Exosomes: innovative biomarkers leading the charge in non-invasive cancer diagnostics	43
Targeting HSF1 for cancer treatment: mechanisms and inhibitor development	43
Revolutionizing drug delivery: low-intensity pulsed ultrasound (LIPUS)-driven deep penetration into hypoxic tumor microenvironments of cholangiocarcinoma	42
Comprehensive overview of Nrf2-related epigenetic regulations involved in ischemia-reperfusion injury	42
A novel afterglow nanoreporter for monitoring cancer therapy	42
The evolving understanding of systemic mechanisms in organ-specific IgA nephropathy: a focus on gut-kidney crosstalk	42
Platinum-based drugs for cancer therapy and anti-tumor strategies	42
TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma	42
Tumor-selective dye-based histological electrophoresis enables intraoperative tumor diagnosis via tumor-specific enhancement	42
Trop2-targeted therapies in solid tumors: advances and future directions	42
Autophagy-enhanced nanosonosensitizer mediated sonodynamic therapy for post-myocardial infarction neuromodulation and arrhythmia prevention	41
Metabolic Targeting of Oxidative Phosphorylation Enhances Chemosensitivity in Triple-Negative Breast Cancer via a Synergistic Nanomedicine	41
Emulating interactions between microorganisms and tumor microenvironment to develop cancer theranostics	41
SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex	41
PIM1 instigates endothelial-to-mesenchymal transition to aggravate atherosclerosis	41
Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss	41
Low hepatic artery blood flow mediates NET extravasation through the regulation of PIEZO1/SRC signaling to induce biliary complications after liver transplantation	41
Bifidobacterium breve-derived indole-3-lactic acid ameliorates colitis-associated tumorigenesis by directing the differentiation of immature colonic macrophages	41
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics	40
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer	40
CLP36 promotes p53 deficient sarcoma progression through suppression of atrophin-1 interacting protein-4 (AIP-4)-dependent degradation of YAP1	40
Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants	40
Ultrasound-controlled MXene-based Schottky heterojunction improves anti-infection and osteogenesis properties	40
Faecal microbiome and metabolic signatures in rectal neuroendocrine tumors	40
Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression: Erratum	40
Inhibitor screening using microarray identifies the high capacity of neutralizing antibodies to Spike variants in SARS-CoV-2 infection and vaccination	40
In vivo molecular imaging of breast cancer metabolic heterogeneity using [1-13C]pyruvate-d3 hyperpolarized by reversible exchange with parahydrogen	40
Conditional ablation of DIS3L2 ribonuclease in pre-meiotic germ cells causes defective spermatogenesis and infertility in male mice	40
MiR-155 deficiency protects renal tubular epithelial cells from telomeric and genomic DNA damage in cisplatin-induced acute kidney injury	40
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing	39
3D bioprinting of prefabricated artificial skin with multicomponent hydrogel for skin and hair follicle regeneration	39
LRG1 inhibition promotes acute pancreatitis recovery by inducing cholecystokinin Type 1 receptor expression via Akt	39
Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms	39
Unlocking potential of oxytocin: improving intracranial lymphatic drainage for Alzheimer's disease treatment	39
Integrative biology of extracellular vesicles in diabetes mellitus and diabetic complications	39
DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis	39
Modulation of brain immune microenvironment and cellular dynamics in systemic inflammation	39
From molecules to medicine: thiol selective bioconjugation in synthesis of diagnostic and therapeutic radiopharmaceuticals	39
Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds	39
Self-Assembling Hydrogels of Naproxen-Conjugated Peptides for Osteoarthritis Treatment	39
Thermal-responsive ultrasound activatable in situ production of therapeutics for real-time imaging and targeted tumor therapy	39
Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity	39
Autophagy-driven lipid regulation by an herbal decoction alleviates cardiac lipotoxicity in severe acute pancreatitis	39
Mesenchymal stromal cells and alpha-1 antitrypsin have a strong synergy in modulating inflammation and its resolution	38
Label-free optical metabolic imaging of adipose tissues for prediabetes diagnosis	38
Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration	38
Theranostics in the vasculature: bioeffects of ultrasound and microbubbles to induce vascular shutdown	38
USP14 modulates stem-like properties, tumorigenicity, and radiotherapy resistance in glioblastoma stem cells through stabilization of MST4-phosphorylated ALKBH5	37
Inflammatory extracellular vesicles prompt heart dysfunction via TLR4-dependent NF-κB activation: Erratum	37
Divergent splicing factor SRSF1 signaling promotes inflammation post-CME: the SRSF1/ENPP3 axis acts via inhibition of BRD4 O-GlcNAcylation to enhance NF-κB activation and accelerate heart failure	37
Biomimetic piezoelectric hydrogel system for energy metabolism reprogramming in spinal cord injury repair	37
α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer	37
Sequentially targeting and intervening mutual Polo-like Kinase 1 on CAFs and tumor cells by dual targeting nano-platform for cholangiocarcinoma treatment	37