Theranostics

Papers
(The median citation count of Theranostics is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-09-01 to 2024-09-01.)
ArticleCitations
Engineering exosomes for targeted drug delivery720
Turning cold tumors into hot tumors by improving T-cell infiltration396
Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance368
Immunopathogenesis and treatment of cytokine storm in COVID-19328
Platinum-based drugs for cancer therapy and anti-tumor strategies319
Ferroptosis as a novel therapeutic target for cardiovascular disease316
The double-edged roles of ROS in cancer prevention and therapy308
Selective autophagy of intracellular organelles: Recent research advances248
Strategies in the delivery of Cas9 ribonucleoprotein for CRISPR/Cas9 genome editing243
Recent progress in nanomedicine for enhanced cancer chemotherapy235
Inflammation-related pyroptosis, a novel programmed cell death pathway, and its crosstalk with immune therapy in cancer treatment228
Siglec15 shapes a non-inflamed tumor microenvironment and predicts the molecular subtype in bladder cancer226
Macrophage membrane functionalized biomimetic nanoparticles for targeted anti-atherosclerosis applications222
Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy216
Metabolic regulatory crosstalk between tumor microenvironment and tumor-associated macrophages184
Breast cancer exosomes contribute to pre-metastatic niche formation and promote bone metastasis of tumor cells180
Manganese porphyrin-based metal-organic framework for synergistic sonodynamic therapy and ferroptosis in hypoxic tumors179
Pyroptosis in inflammatory diseases and cancer166
m6A regulator-based methylation modification patterns characterized by distinct tumor microenvironment immune profiles in colon cancer152
Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury151
Coronary microvascular injury in myocardial infarction: perception and knowledge for mitochondrial quality control146
Recent strategies for nano-based PTT combined with immunotherapy: from a biomaterial point of view141
Targeted delivery of neural progenitor cell-derived extracellular vesicles for anti-inflammation after cerebral ischemia139
Metabolic reprogramming of cancer-associated fibroblasts and its effect on cancer cell reprogramming138
Single-cell RNA sequencing reveals a pro-invasive cancer-associated fibroblast subgroup associated with poor clinical outcomes in patients with gastric cancer137
An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment137
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota135
Tumor microenvironment remodeling and tumor therapy based on M2-like tumor associated macrophage-targeting nano-complexes133
Designer exosomes for targeted and efficient ferroptosis induction in cancer via chemo-photodynamic therapy131
Cellular mitophagy: Mechanism, roles in diseases and small molecule pharmacological regulation129
Progenitor cell-derived exosomes endowed with VEGF plasmids enhance osteogenic induction and vascular remodeling in large segmental bone defects128
Role of prostaglandin E2 in tissue repair and regeneration125
Small molecule-based treatment approaches for intervertebral disc degeneration: Current options and future directions121
SERS Tags for Biomedical Detection and Bioimaging121
Exosomal miR-500a-5p derived from cancer-associated fibroblasts promotes breast cancer cell proliferation and metastasis through targeting USP28120
Recent advances in innovative strategies for enhanced cancer photodynamic therapy118
IGF2BP1 overexpression stabilizes PEG10 mRNA in an m6A-dependent manner and promotes endometrial cancer progression115
Circular RNA circDLC1 inhibits MMP1-mediated liver cancer progression via interaction with HuR115
Glioma stem cells and their roles within the hypoxic tumor microenvironment115
Engineered exosomes: desirable target-tracking characteristics for cerebrovascular and neurodegenerative disease therapies115
Stimuli-activatable nanomedicine meets cancer theranostics114
Targeting iron metabolism in cancer therapy114
Repurposing ferumoxytol: Diagnostic and therapeutic applications of an FDA-approved nanoparticle112
Cisplatin-resistant NSCLC cells induced by hypoxia transmit resistance to sensitive cells through exosomal PKM2109
Recent Advances in Photosensitizers as Multifunctional Theranostic Agents for Imaging-Guided Photodynamic Therapy of Cancer108
Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I108
Lactate-induced M2 polarization of tumor-associated macrophages promotes the invasion of pituitary adenoma by secreting CCL17107
Exosome-inflammasome crosstalk and their roles in inflammatory responses107
AdMSC-derived exosomes alleviate acute lung injury via transferring mitochondrial component to improve homeostasis of alveolar macrophages106
Circular RNA circRHOBTB3 represses metastasis by regulating the HuR-mediated mRNA stability of PTBP1 in colorectal cancer106
ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1105
Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model103
A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models103
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization101
tRNA-derived fragments: Mechanisms underlying their regulation of gene expression and potential applications as therapeutic targets in cancers and virus infections101
Current status of sorafenib nanoparticle delivery systems in the treatment of hepatocellular carcinoma101
Pectin supplement significantly enhanced the anti-PD-1 efficacy in tumor-bearing mice humanized with gut microbiota from patients with colorectal cancer100
Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment99
M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 pathway after ischemic stroke in mice97
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction96
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy96
Mitochondria-targeted and ultrasound-responsive nanoparticles for oxygen and nitric oxide codelivery to reverse immunosuppression and enhance sonodynamic therapy for immune activation96
Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications95
Holo-lactoferrin: the link between ferroptosis and radiotherapy in triple-negative breast cancer95
Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria94
Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets94
Chondrocyte-specific genomic editing enabled by hybrid exosomes for osteoarthritis treatment92
Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy92
Tailoring noble metal nanoparticle designs to enable sensitive lateral flow immunoassay91
Tumor suppressor DRD2 facilitates M1 macrophages and restricts NF-κB signaling to trigger pyroptosis in breast cancer90
Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma90
Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles89
High fat diet, gut microbiome and gastrointestinal cancer89
Electroacupuncture ameliorates intestinal inflammation by activating α7nAChR-mediated JAK2/STAT3 signaling pathway in postoperative ileus89
GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy87
Cancer-derived exosomal miR-138-5p modulates polarization of tumor-associated macrophages through inhibition of KDM6B86
Assessing PD-L1 expression in non-small cell lung cancer and predicting responses to immune checkpoint inhibitors using deep learning on computed tomography images86
H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts84
ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation82
The role of microRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies82
A skeleton muscle model using GelMA-based cell-aligned bioink processed with an electric-field assisted 3D/4D bioprinting82
Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion82
CircUbe3a from M2 macrophage-derived small extracellular vesicles mediates myocardial fibrosis after acute myocardial infarction81
Exosomal lncRNA-H19 promotes osteogenesis and angiogenesis through mediating Angpt1/Tie2-NO signaling in CBS-heterozygous mice81
Fibroblast activation protein-based theranostics in cancer research: A state-of-the-art review81
TGF-β loaded exosome enhances ischemic wound healing in vitro and in vivo81
Exosomal miR-21 from tubular cells contributes to renal fibrosis by activating fibroblasts via targeting PTEN in obstructed kidneys79
SARM1 promotes neuroinflammation and inhibits neural regeneration after spinal cord injury through NF-κB signaling79
Glucose biosensors in clinical practice: principles, limits and perspectives of currently used devices79
Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment78
Endothelial cell infection and dysfunction, immune activation in severe COVID-1977
SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells76
Triptolide: pharmacological spectrum, biosynthesis, chemical synthesis and derivatives76
Ultrasound-mediated augmented exosome release from astrocytes alleviates amyloid-β-induced neurotoxicity75
MRI-traceable theranostic nanoparticles for targeted cancer treatment75
Silencing of METTL3 effectively hinders invasion and metastasis of prostate cancer cells74
MLKL: Functions beyond serving as the Executioner of Necroptosis74
Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis74
The pivotal roles of exosomes derived from endogenous immune cells and exogenous stem cells in myocardial repair after acute myocardial infarction74
Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma74
Silk fibroin-based biomaterials for cartilage/osteochondral repair74
Impact of sodium glucose cotransporter 2 (SGLT2) inhibitors on atherosclerosis: from pharmacology to pre-clinical and clinical therapeutics73
Tubular epithelial cell-to-macrophage communication forms a negative feedback loop via extracellular vesicle transfer to promote renal inflammation and apoptosis in diabetic nephropathy72
Role of serotonin receptor signaling in cancer cells and anti-tumor immunity72
Catalytic patch with redox Cr/CeO2 nanozyme of noninvasive intervention for brain trauma71
The twin cytokines interleukin-34 and CSF-1: masterful conductors of macrophage homeostasis71
A nano-predator of pathological MDMX construct by clearable supramolecular gold(I)-thiol-peptide complexes achieves safe and potent anti-tumor activity71
Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK/SIRT1/PGC-1α pathway in rats70
Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellu70
Circular RNA cancer vaccines drive immunity in hard-to-treat malignancies70
Single-cell RNA landscape of the osteoimmunology microenvironment in periodontitis70
Turmeric-derived nanovesicles as novel nanobiologics for targeted therapy of ulcerative colitis70
Targeted inhibition of SIRT6 via engineered exosomes impairs tumorigenesis and metastasis in prostate cancer69
Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m6A signaling69
Nasal administration of mitochondria reverses chemotherapy-induced cognitive deficits69
Nasopharyngeal carcinoma ecology theory: cancer as multidimensional spatiotemporal “unity of ecology and evolution” pathological ecosystem69
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms68
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel68
3D bioprinting in cardiac tissue engineering68
Metal-phenolic networks: facile assembled complexes for cancer theranostics67
Large-scale tumor-associated collagen signatures identify high-risk breast cancer patients67
Machine learning-based identification of tumor-infiltrating immune cell-associated lncRNAs for improving outcomes and immunotherapy responses in patients with low-grade glioma67
Harnessing Tissue-derived Extracellular Vesicles for Osteoarthritis Theranostics67
COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges67
Fully end-to-end deep-learning-based diagnosis of pancreatic tumors66
The 2020 race towards SARS-CoV-2 specific vaccines66
Circular RNA in pancreatic cancer: a novel avenue for the roles of diagnosis and treatment66
Lipid nanoparticles for delivery of RNA therapeutics: Current status and the role of in vivo imaging66
Manganese-deposited iron oxide promotes tumor-responsive ferroptosis that synergizes the apoptosis of cisplatin66
Candida albicans disorder is associated with gastric carcinogenesis65
Hsa_circ_0030042 regulates abnormal autophagy and protects atherosclerotic plaque stability by targeting eIF4A365
The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy65
Anti-PD-L1 peptide-conjugated prodrug nanoparticles for targeted cancer immunotherapy combining PD-L1 blockade with immunogenic cell death65
Extracellular vesicles derived from hypoxic glioma stem-like cells confer temozolomide resistance on glioblastoma by delivering miR-30b-3p65
ZEB1 enhances Warburg effect to facilitate tumorigenesis and metastasis of HCC by transcriptionally activating PFKM64
The crosstalk between m6A RNA methylation and other epigenetic regulators: a novel perspective in epigenetic remodeling64
TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG64
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents64
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics63
Recent advances in nanotechnology for eradicating bacterial biofilm62
Prussian blue nanozyme-mediated nanoscavenger ameliorates acute pancreatitis via inhibiting TLRs/NF-κB signaling pathway62
Cellular senescence in hepatocellular carcinoma induced by a long non-coding RNA-encoded peptide PINT87aa by blocking FOXM1-mediated PHB262
FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts61
Exosome-based Ldlr gene therapy for familial hypercholesterolemia in a mouse model61
Recent advances in supramolecular antidotes61
Nanofibrous nerve guidance conduits decorated with decellularized matrix hydrogel facilitate peripheral nerve injury repair60
Effective tools for RNA-derived therapeutics: siRNA interference or miRNA mimicry60
Suppressing Sart1 to modulate macrophage polarization by siRNA-loaded liposomes: a promising therapeutic strategy for pulmonary fibrosis59
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation59
Single-cell landscape reveals active cell subtypes and their interaction in the tumor microenvironment of gastric cancer59
Synergistic enhancement of tendon-to-bone healing via anti-inflammatory and pro-differentiation effects caused by sustained release of Mg2+/curcumin from injectable self-healing hydrogels58
ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN358
Ferroptotic stress promotes macrophages against intracellular bacteria58
Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies58
Metabolomic profiling reveals amino acid and carnitine alterations as metabolic signatures in psoriasis58
Exosome-mediated delivery of an anti-angiogenic peptide inhibits pathological retinal angiogenesis58
Therapeutic aptamer targeting sclerostin loop3 for promoting bone formation without increasing cardiovascular risk in osteogenesis imperfecta mice57
Targeting regulated cell death in tumor nanomedicines57
A novel STAT3 inhibitor W2014-S regresses human non-small cell lung cancer xenografts and sensitizes EGFR-TKI acquired resistance57
Cancer photo-immunotherapy: from bench to bedside56
Selenium nanoparticles alleviate ischemia reperfusion injury-induced acute kidney injury by modulating GPx-1/NLRP3/Caspase-1 pathway56
Histone H3K27 methyltransferase EZH2 and demethylase JMJD3 regulate hepatic stellate cells activation and liver fibrosis56
Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis56
MYBL2 disrupts the Hippo-YAP pathway and confers castration resistance and metastatic potential in prostate cancer55
Inhibitory effect of PPARγ on NLRP3 inflammasome activation55
A hydrogen peroxide economizer for on-demand oxygen production-assisted robust sonodynamic immunotherapy55
HMGA2 facilitates colorectal cancer progression via STAT3-mediated tumor-associated macrophage recruitment55
EZH2 activates CHK1 signaling to promote ovarian cancer chemoresistance by maintaining the properties of cancer stem cells54
Single-cell transcriptome profiling reveals vascular endothelial cell heterogeneity in human skin54
Harnessing the tunable cavity of nanoceria for enhancing Y-27632-mediated alleviation of ocular hypertension54
Recent progress of carbon dots in targeted bioimaging and cancer therapy53
Extracellular vesicle-shuttled miRNAs: a critical appraisal of their potential as nano-diagnostics and nano-therapeutics in type 2 diabetes mellitus and its cardiovascular complications53
Therapeutic potential of garlic chive-derived vesicle-like nanoparticles in NLRP3 inflammasome-mediated inflammatory diseases53
Increased photodynamic therapy sensitization in tumors using a nitric oxide-based nanoplatform with ATP-production blocking capability52
Recent progress in cryoablation cancer therapy and nanoparticles mediated cryoablation52
Application of mesenchymal stem cell therapy for aging frailty: from mechanisms to therapeutics52
Targeted delivery of extracellular vesicles in heart injury52
Development of nucleic acid aptamer-based lateral flow assays: A robust platform for cost-effective point-of-care diagnosis52
Activatable NIR-II organic fluorescent probes for bioimaging52
Immunosuppression in tumor immune microenvironment and its optimization from CAR-T cell therapy52
Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy51
CXCL12-mediated monocyte transmigration into brain perivascular space leads to neuroinflammation and memory deficit in neuropathic pain51
METTL3-mediated N6-methyladenosine modification governs pericyte dysfunction during diabetes-induced retinal vascular complication51
Engineering extracellular vesicles with platelet membranes fusion enhanced targeted therapeutic angiogenesis in a mouse model of myocardial ischemia reperfusion51
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation50
CD45RO-CD8+ T cell-derived exosomes restrict estrogen-driven endometrial cancer development via the ERβ/miR-765/PLP2/Notch axis50
Identification and validation of hypoxia-derived gene signatures to predict clinical outcomes and therapeutic responses in stage I lung adenocarcinoma patients50
The 14-3-3σ protein promotes HCC anoikis resistance by inhibiting EGFR degradation and thereby activating the EGFR-dependent ERK1/2 signaling pathway50
Photosensitizer-driven nanoassemblies of homodimeric prodrug for self-enhancing activation and synergistic chemo-photodynamic therapy50
Exosome-mediated delivery of inflammation-responsive Il-10 mRNA for controlled atherosclerosis treatment50
Conditioned medium from adipose-derived stem cells attenuates ischemia/reperfusion-induced cardiac injury through the microRNA-221/222/PUMA/ETS-1 pathway49
Recent advances in the medical applications of hemostatic materials49
SGLT2 inhibitor dapagliflozin reduces endothelial dysfunction and microvascular damage during cardiac ischemia/reperfusion injury through normalizing the XO-SERCA2-CaMKII-coffilin pathways48
Distinct placental molecular processes associated with early-onset and late-onset preeclampsia48
NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin48
Organ-specific cholesterol metabolic aberration fuels liver metastasis of colorectal cancer48
Extracellular vesicles as bioactive nanotherapeutics: An emerging paradigm for regenerative medicine48
Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis48
Targeting ferroptosis-based cancer therapy using nanomaterials: strategies and applications48
Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage48
Non-invasive photobiomodulation treatment in an Alzheimer Disease-like transgenic rat model48
Integrative analysis of long extracellular RNAs reveals a detection panel of noncoding RNAs for liver cancer47
M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice47
Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling47
GPR43 deficiency protects against podocyte insulin resistance in diabetic nephropathy through the restoration of AMPKα activity47
EGFR inhibition blocks cancer stem cell clustering and lung metastasis of triple negative breast cancer47
Estrogen-induced circRNA, circPGR, functions as a ceRNA to promote estrogen receptor-positive breast cancer cell growth by regulating cell cycle-related genes47
Deficiency of the X-inactivation escaping gene KDM5C in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis47
Metformin in cardiovascular diabetology: a focused review of its impact on endothelial function47
TGFBI secreted by tumor-associated macrophages promotes glioblastoma stem cell-driven tumor growth via integrin αvβ5-Src-Stat3 signaling46
An electroporation strategy to synthesize the membrane-coated nanoparticles for enhanced anti-inflammation therapy in bone infection46
MicroRNA-146a switches microglial phenotypes to resist the pathological processes and cognitive degradation of Alzheimer's disease46
Targeting ATF4-dependent pro-survival autophagy to synergize glutaminolysis inhibition46
Mutational spectrum and precision oncology for biliary tract carcinoma46
Silicon nanowires decorated with platinum nanoparticles were applied for photothermal-enhanced sonodynamic therapy46
Converged Rab37/IL-6 trafficking and STAT3/PD-1 transcription axes elicit an immunosuppressive lung tumor microenvironment46
Oral delivery of protein and peptide drugs: from non-specific formulation approaches to intestinal cell targeting strategies46
Smart magnetic resonance imaging-based theranostics for cancer46
KDM1A promotes thyroid cancer progression and maintains stemness through the Wnt/β-catenin signaling pathway46
PLAGL2 promotes the proliferation and migration of gastric cancer cells via USP37-mediated deubiquitination of Snail146
Artificial intelligence in pancreatic cancer45
Macitentan improves antitumor immune responses by inhibiting the secretion of tumor-derived extracellular vesicle PD-L145
Prodromal neuroinflammatory, cholinergic and metabolite dysfunction detected by PET and MRS in the TgF344-AD transgenic rat model of AD: a collaborative multi-modal study45
Multi-omics study of silicosis reveals the potential therapeutic targets PGD2 and TXA245
Multi-omics study reveals that statin therapy is associated with restoration of gut microbiota homeostasis and improvement in outcomes in patients with acute coronary syndrome44
Molecular imaging and biochemical response assessment after a single cycle of [225Ac]Ac-PSMA-617/[177Lu]Lu-PSMA-617 tandem therapy in mCRPC patients who have progressed on [44
Acellular cardiac scaffolds enriched with MSC-derived extracellular vesicles limit ventricular remodelling and exert local and systemic immunomodulation in a myocardial infarction porcine model44
Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo44
Tumor cell-activated “Sustainable ROS Generator” with homogeneous intratumoral distribution property for improved anti-tumor therapy44
Dynamic monitoring of circulating tumor DNA to predict prognosis and efficacy of adjuvant chemotherapy after resection of colorectal liver metastases43
Role of p53 in breast cancer progression: An insight into p53 targeted therapy43
Dodging blood brain barrier with “nano” warriors: Novel strategy against ischemic stroke43
Ovarian hormones-autophagy-immunity axis in menstruation and endometriosis43
N6-methyladenosine-mediated LDHA induction potentiates chemoresistance of colorectal cancer cells through metabolic reprogramming43
Neutrophil-derived trail is a proinflammatory subtype of neutrophil-derived extracellular vesicles43
LncRNA PRADX-mediated recruitment of PRC2/DDX5 complex suppresses UBXN1 expression and activates NF-κB activity, promoting tumorigenesis42
Progressive stretch enhances growth and maturation of 3D stem-cell-derived myocardium42
Inhibition of tumor progression and M2 microglial polarization by extracellular vesicle-mediated microRNA-124 in a 3D microfluidic glioblastoma microenvironment42
WD repeat domain 5 promotes chemoresistance and Programmed Death-Ligand 1 expression in prostate cancer42
Antibacterial PDT nanoplatform capable of releasing therapeutic gas for synergistic and enhanced treatment against deep infections42
Rapid design and development of CRISPR-Cas13a targeting SARS-CoV-2 spike protein42
Blockade of deubiquitinating enzyme PSMD14 overcomes chemoresistance in head and neck squamous cell carcinoma by antagonizing E2F1/Akt/SOX2-mediated stemness42
Radiomics in prostate cancer imaging for a personalized treatment approach - current aspects of methodology and a systematic review on validated studies42
SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation41
Temporal analysis of type 1 interferon activation in tumor cells following external beam radiotherapy or targeted radionuclide therapy41
IL20RA signaling enhances stemness and promotes the formation of an immunosuppressive microenvironment in breast cancer41
miR-375 prevents high-fat diet-induced insulin resistance and obesity by targeting the aryl hydrocarbon receptor and bacterial tryptophanase (tnaA) gene41
Overexpression of S100A9 in obesity impairs macrophage differentiation via TLR4-NFkB-signaling worsening inflammation and wound healing41
How to improve photodynamic therapy-induced antitumor immunity for cancer treatment?41
The histone acetyltransferase HBO1 functions as a novel oncogenic gene in osteosarcoma41
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