OOIR: Observatory of International Research

Papers

(The H4-Index of Theranostics is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	647
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	256
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	256
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	232
Glucosylceramide regulates depression through activating peroxisome proliferator-activated receptor gamma in dorsal striatum	217
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	210
Self-boosting targeted anticancer therapy via cancer cell self-reprogramming with GGT-targeting oxidative stress nanoamplifiers	209
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	205
The LMIT: Light-mediated minimally-invasive theranostics in oncology	200
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	189
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	172
Focused ultrasound-enhanced nose-to-brain delivery of a therapeutic antibody in a large-animal model	172
“Electron transport chain interference” strategy of amplified bacterial ferroptosis and defect-engineered nanozyme for diabetic wound healing	164
Flowerbed-inspired biomimetic 3D-printed scaffolds functionalized with urine-derived stem cell exosomes promote alveolar bone regeneration by regulating energy metabolism	162
Exosomal immune decoy integrates cfDNA scavenging and mTOR inhibition for synergistic lupus nephritis therapy	158
Integrating the hallmarks of cancer into autophagy: a perspective from underlying mechanisms to therapeutic strategies	158
Primary Cilium Forces Neuroendocrine Shift in Prostate Cancer through YAP1 Repression and Reduced Mitochondrial Activity	153
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	140
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	140
Targeted delivery of anti-miRNA21 sensitizes PD-L1^high tumor to immunotherapy by promoting immunogenic cell death	133
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	133
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	133
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	130
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	127
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	123

Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	121
A robust asymmetric bioadhesive patch for sutureless intestinal repair to prevent anastomotic leakage and postoperative adhesion	112
Noninvasive closed-loop acoustic brain-computer interface for seizure control	109
Recent progress of nano-drugs in neutron capture therapy	108
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	107
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	105
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	104
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m⁶A/YTHDF1-mediated enhancement on ATG3 stability	103
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	101
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	99
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	98
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	97
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	97
ASIC1a Induces Excessive Mitophagy and PANoptosis of Chondrocyte by the Inhibition of SIRT3 Mitochondrial Translocation	96
Myeloid cell-specific β2-adrenergic receptor deletion improves early cardiac injury resolution via de-repression of Anxa1	95
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	94
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	94
Biosynthetic gas vesicles as a novel ultrasound contrast agent for diagnosing and treating myocardial infarction	93
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	92
Future opportunities and nuances with the use of PSMA PET in prostate cancer (MD PET 1)	92
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	91
The emerging role of Piezo1 in the musculoskeletal system and disease	90
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	90
First-in-human study of an optimized, potential kit-type, SSTR antagonist ⁶⁸Ga-DATA^5m-LM4 in patients with metastatic neuroendocrine tumors	89
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	89
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	87
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	86
Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum	85
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	83
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy	81
Antibody-induced internalization and degradation of PLA2R amplifies CD4⁺ T cell activation	81
Supercharging CAR-T cells through transcriptional and epigenetic armoring	80
The first abdominal aortic aneurysm organoid model replicates complex microenvironment for in vitro disease study	79
Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer	79
Connective tissue growth factor contributes to resistance to anti-angiogenic therapies in renal cancer	79
Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection	78
TRIM4 enhances small-molecule-induced neddylated-degradation of CORO1A for triple negative breast cancer therapy	78
Quantitative assessment of extravasation of IL-15-secreting MSLN-CAR-NK-92 cells using tumor transparency imaging	78
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution	78
Cell-free secretome of CD56 ^bright CD16 ^bright directly reprogrammed NK cells enhances wound heali	77
The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer	76
Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation	76
Intermittent fasting reprograms the brain proteome to prevent synaptic degeneration and cognitive impairment in vascular dementia	76
Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease	75
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	75
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy	75
Pathologically responsive ZnSrMo-LDH/Cu nanozymes with cascade antioxidant and angiogenic functions for myocardial ischemia-reperfusion treatment	74
Development of a nanoparticle-based immunotherapy targeting CD137 for nasopharyngeal carcinoma treatment	74
Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma	74