OOIR: Observatory of International Research

Papers

(The H4-Index of Theranostics is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	599
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	236
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	231
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	217
Biosynthetic gas vesicles as a novel ultrasound contrast agent for diagnosing and treating myocardial infarction	195
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	192
Glucosylceramide regulates depression through activating peroxisome proliferator-activated receptor gamma in dorsal striatum	190
Flowerbed-inspired biomimetic 3D-printed scaffolds functionalized with urine-derived stem cell exosomes promote alveolar bone regeneration by regulating energy metabolism	189
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	181
Self-boosting targeted anticancer therapy via cancer cell self-reprogramming with GGT-targeting oxidative stress nanoamplifiers	169
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	160
ASIC1a Induces Excessive Mitophagy and PANoptosis of Chondrocyte by the Inhibition of SIRT3 Mitochondrial Translocation	153
The LMIT: Light-mediated minimally-invasive theranostics in oncology	148
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	143
Targeted delivery of anti-miRNA21 sensitizes PD-L1^high tumor to immunotherapy by promoting immunogenic cell death	140
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	137
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	135
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	129
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	125
Future opportunities and nuances with the use of PSMA PET in prostate cancer (MD PET 1)	125
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	124
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	120
Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	120
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	115
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	110

RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	107
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	103
Noninvasive closed-loop acoustic brain-computer interface for seizure control	102
Focused ultrasound-enhanced nose-to-brain delivery of a therapeutic antibody in a large-animal model	101
Myeloid cell-specific β2-adrenergic receptor deletion improves early cardiac injury resolution via de-repression of Anxa1	99
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	96
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	95
The emerging role of Piezo1 in the musculoskeletal system and disease	94
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m⁶A/YTHDF1-mediated enhancement on ATG3 stability	94
“Electron transport chain interference” strategy of amplified bacterial ferroptosis and defect-engineered nanozyme for diabetic wound healing	92
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	88
Primary Cilium Forces Neuroendocrine Shift in Prostate Cancer through YAP1 Repression and Reduced Mitochondrial Activity	87
Exosomal immune decoy integrates cfDNA scavenging and mTOR inhibition for synergistic lupus nephritis therapy	87
Integrating the hallmarks of cancer into autophagy: a perspective from underlying mechanisms to therapeutic strategies	87
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	86
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	84
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	84
Recent progress of nano-drugs in neutron capture therapy	82
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	82
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	81
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	81
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	81
Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies	78
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	78
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	77
First-in-human study of an optimized, potential kit-type, SSTR antagonist ⁶⁸Ga-DATA^5m-LM4 in patients with metastatic neuroendocrine tumors	75
Pre-metastatic niche: from revealing the molecular and cellular mechanisms to the clinical applications in breast cancer metastasis	75
Cell-free secretome of CD56 ^bright CD16 ^bright directly reprogrammed NK cells enhances wound heali	75
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	74
Revolutionizing cancer treatment: the emerging potential and potential challenges of in vivo self-processed CAR cell therapy	74
CBX4 suppresses CD8⁺ T cell antitumor immunity by reprogramming glycolytic metabolism	73
The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer	73
Quantitative assessment of extravasation of IL-15-secreting MSLN-CAR-NK-92 cells using tumor transparency imaging	73
Development of a nanoparticle-based immunotherapy targeting CD137 for nasopharyngeal carcinoma treatment	71
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution	71
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	71
Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection	71
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	70
Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum	68
Antibody-induced internalization and degradation of PLA2R amplifies CD4⁺ T cell activation	67
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	67
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	67