OOIR: Observatory of International Research

Papers

(The H4-Index of Theranostics is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy	630
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	464
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	380
Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	368
The LMIT: Light-mediated minimally-invasive theranostics in oncology	223
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	216
Emerging microfluidics-enabled platforms for osteoarthritis management: from benchtop to bedside	216
Dual-targeted magnetic mesoporous silica nanoparticles reduce brain amyloid-β burden via depolymerization and intestinal metabolism	213
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	185
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	174
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	166
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	162
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	160
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	160
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold	156
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	155
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	155
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype	149
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	144
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	142
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	139
5-Aminolevulinate improves metabolic recovery and cell survival of the liver following cold preservation	136
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model	133
Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal stromal cells after hypoxic-ischaemic brain damage	131
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	129

GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	128
A low molecular weight multifunctional theranostic molecule for the treatment of prostate cancer	122
Biosynthetic gas vesicles as a novel ultrasound contrast agent for diagnosing and treating myocardial infarction	121
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy	119
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	119
Recent progress of nano-drugs in neutron capture therapy	118
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	117
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m⁶A/YTHDF1-mediated enhancement on ATG3 stability	111
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	109
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	107
Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity — Introducing High NET Affinity PET Probe ¹⁸F-AF78	107
Noninvasive closed-loop acoustic brain-computer interface for seizure control	107
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms	106
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	105
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	102
High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease	101
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	99
The emerging role of Piezo1 in the musculoskeletal system and disease	98
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	98
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	98
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	96
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	96
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	95
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	94
Targeted delivery of anti-miRNA21 sensitizes PD-L1^high tumor to immunotherapy by promoting immunogenic cell death	91
FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts	91
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	88
Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial: Erratum	87
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy	86
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	86
A Transferrin-Conjugated Hollow Nanoplatform for Redox-Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions: Erratum	86
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α: Erratum	86
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy	85
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	85
Identification of early invisible acute ischemic stroke in non-contrast computed tomography using two-stage deep-learning model	84
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	84
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	82
TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response	82
Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication	81
Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation	80
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration	79
Revolutionizing cancer treatment: the emerging potential and potential challenges of in vivo self-processed CAR cell therapy	78
Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury	78
CBX4 suppresses CD8⁺ T cell antitumor immunity by reprogramming glycolytic metabolism	78
Engineering of donor-acceptor-donor curcumin analogues as near-infrared fluorescent probes for in vivo imaging of amyloid-β species	76
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	76
Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development	76
The first abdominal aortic aneurysm organoid model replicates complex microenvironment for in vitro disease study	75
Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation	74
Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma	74