OOIR: Observatory of International Research

Papers

(The H4-Index of Theranostics is 66. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
A low molecular weight multifunctional theranostic molecule for the treatment of prostate cancer	523
The LMIT: Light-mediated minimally-invasive theranostics in oncology	348
A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy	316
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	280
Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal stromal cells after hypoxic-ischaemic brain damage	188
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype	186
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	180
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	171
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	154
Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	146
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	145
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	141
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	132
High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease	125
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	122
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	122
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	121
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m⁶A/YTHDF1-mediated enhancement on ATG3 stability	120
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	118
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold	116
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	115
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	115
The emerging role of Piezo1 in the musculoskeletal system and disease	106
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	106
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model	102

Targeted delivery of anti-miRNA21 sensitizes PD-L1^high tumor to immunotherapy by promoting immunogenic cell death	102
Emerging microfluidics-enabled platforms for osteoarthritis management: from benchtop to bedside	99
Dual-targeted magnetic mesoporous silica nanoparticles reduce brain amyloid-β burden via depolymerization and intestinal metabolism	98
Recent progress of nano-drugs in neutron capture therapy	96
Noninvasive closed-loop acoustic brain-computer interface for seizure control	95
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	94
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	91
5-Aminolevulinate improves metabolic recovery and cell survival of the liver following cold preservation	91
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	88
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	87
Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity — Introducing High NET Affinity PET Probe ¹⁸F-AF78	85
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	84
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy	84
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	84
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms	83
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	82
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	82
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	82
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	80
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	80
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	79
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	78
FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts	76
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	76
Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial: Erratum	75
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	74
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	73
First-in-human study of an optimized, potential kit-type, SSTR antagonist ⁶⁸Ga-DATA^5m-LM4 in patients with metastatic neuroendocrine tumors	72
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α: Erratum	72
A Transferrin-Conjugated Hollow Nanoplatform for Redox-Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions: Erratum	71
Optic chiasmatic potential by endoscopically implanted skull base microinvasive biosensor: a brain-machine interface approach for anterior visual pathway assessment	70
The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer	70
Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer	70
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution	69
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration	69
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	68
Extracellular vesicles: catching the light of intercellular communication in fibrotic liver diseases	68
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy	68
Supercharging CAR-T cells through transcriptional and epigenetic armoring	68
Targeting formyl peptide receptor 2 to suppress neuroinflammation in neuromyelitis optica spectrum disorder	67
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	67