OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cancer is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Salmonella-induced inhibition of β3-adrenoceptor expression in tumors and reduces tumor metastasis	79
Development of A Nomogram for Progression-free Survival in Patients with Stage II/T3N0 Nasopharyngeal Carcinoma to Explore Different Treatment Modalities	55
PPAR-δ as a prognostic biomarker and its association with immune infiltrates in breast cancer PPAR-δ as a prognostic biomarker and its association with immune infiltrates in breast cancer	55
The impacts of MACC1 gene polymorphisms on urothelial cell carcinoma susceptibility and clinicopathologic characteristics in Taiwan	49
High Expression of RhoF Predicts Worse Overall Survival: A Potential Therapeutic Target for non-M3 Acute Myeloid Leukemia: Erratum	48
Drugging the tumor microenvironment epigenome for therapeutic interventions in NSCLC	46
LncRNA LINC00460 facilitates the proliferation and metastasis of renal cell carcinoma via PI3K/AKT signaling pathway	44
Screening of PDSS1 as a Potential Biomarker for Hepatocellular Carcinoma Based on a Copper-Related Prognostic Signature through Bulk and Single-cell RNA-sequencing Analysis	43
The impact of tumor size on the prognosis and chemotherapy efficacy in stage I/II colon cancer patients	42
WEE1 Inhibitors Mediate Antitumor Effects on Endometrial Cancer through Activation of Innate Immune Responses	42
Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway	41
The immediate risk of cancer and its precursor lesions in women with abnormal cervical glandular cytology	40
HER4 Promotes Osteosarcoma Progression and Predicts Poor Prognosis through the PTEN-PI3K/AKT Pathway: Retraction	40
Tanshinone IIA inhibits cell viability and promotes PUMA-mediated apoptosis of oral squamous cell carcinoma	39
The significance of HAUS1 and its relationship with immune microenvironment in hepatocellular carcinoma	38
Deep learning-based computed tomography urography image analysis for prediction of HER2 status in bladder cancer	37
Neoadjuvant Chemotherapy Can Effectively Avoid Unnecessary Extended Resection for Gastric Cancer with Clinical Evidence of Duodenum or Pancreas Head Involvement	37
Hypoxia-elicited Exosomes Promote the Chemoresistance of Pancreatic Cancer Cells by Transferring LncROR via Hippo Signaling	36
Oncogenic-tsRNA: A novel diagnostic and therapeutic molecule for cancer clinic	35
Shenling Baizhu Decoction (SLBZD) may play a synergistic role of tirelizumab in the treatment of colorectal cancer by influencing the imbalance of colon flora and Tumor microenvironment	34
Potential clinical treatment prospects behind the molecular mechanism of alternative lengthening of telomeres (ALT)	33
Unlocking the Therapeutic Potential: Harnessing miR-125a-5p To Enhance Autophagy and Apoptosis in Pancreatic Cancer through Targeting STAT3	33
Retinoic acid metabolism related gene CYP26B1 promotes tumor stemness and tumor microenvironment remodeling in bladder cancer	32
NEDD1 overexpression increases cell proliferation, tumor immune escape, and drug resistance in LUAD	31
LncRNA HOTAIR Enhances Epithelial-to-mesenchymal Transition to Promote the Migration and Invasion of Liver Cancer by Regulating NUAK1 via Epigenetic Inhibition miR-145-5p Expression	31

The Functional Role of LncRNA UCA1 in Pancreatic Cancer: a mini-review	29
CDH3 Is an Effective Serum Biomarker of Colorectal Cancer Distant Metastasis Patients	29
HSPB8 Facilitates the Oncogenesis and Advancement of Bladder Cancer via Activation of HSP27	29
Mismatch Repair Protein Deficiency and Its Relationship with Clinicopathological Factors in Endometrial Cancer: A Retrospective Study	28
Pan-Cancer Analysis of KANK2: Clinical and Molecular Insights into Tumor Progression and Therapeutic Implications	28
DOK1 facilitates the advancement of ccRCC	28
NEK6 functions as an oncogene to promote the proliferation and metastasis of ovarian cancer	27
CSNK1G2-AS1 promotes metastasis, colony formation and serves as a biomarker in testicular germ cell tumor cells	27
Anti-CD47 Antibody Enhances the Efficacy of Chemotherapy in Patients with Gastric Cancer Liver Metastasis	26
Sarcosine dehydrogenase as an immune infiltration-associated biomarker for the prognosis of hepatocellular carcinoma	26
Insight into the Role of the BCL6B Gene in Biological Functions and Disease Progression	26
A Potential biomarker for the early diagnosis of OSCC: saliva and serum PrP^C	25
Digestive tract reconstruction after laparoscopic proximal gastrectomy for Gastric cancer: A systematic review	24
Spermidine potentiates anti-tumor immune responses and immunotherapy sensitivity in breast cancer	24
Differential diagnosis of benign and malignant ovarian tumors with combined tumor and systemic inflammation-related markers	24
WTAP regulates Mitochondrial damage and Lipid oxidation in HCC by NOA1 mediated m6A modification	24
The Role of Cathepsin B in Pathophysiologies of Non-tumor and Tumor tissues: A Systematic Review	23
PLAU and LAMC2 can predict a poor prognosis in patients with HNSCC	23
PPP1R14B as a potential biomarker for the identification of diagnosis and prognosis affecting tumor immunity, proliferation and migration in prostate cancer	23
Anisomycin has a potential toxicity of promoting cuproptosis in human ovarian cancer stem cells by attenuating YY1/lipoic acid pathway activation	23
The Role of CTNNA1 in Malignancies: An Updated Review	23
The prognostic role of the preoperative platelet to lymphocyte ratio in laryngeal cancer	22
Intercellular Adhesion Molecule 3: Structure, Cellular Functions, and Emerging Role in Human Diseases	22
CCT6A functions as promising diagnostic biomarker and promotes cell proliferation in colorectal cancer	22
Effect of CELSR3 on the Cell Cycle and Apoptosis of Hepatocellular Carcinoma Cells: Erratum	22
A Prognostic Model of Angiogenesis and Neutrophil Extracellular Traps Related Genes Manipulating Tumor Microenvironment in Colon Cancer	22
3,3'-Diindolylmethane plus Eflornithine suppress DNA Replication and Cell Cycle in Esophageal Squamous Cell Carcinoma in vivo	22
KLK7 Involvement in Thyroid Papillary Carcinoma Cell Migration and Invasion by EMT via MAPK/ERK Pathways	22
Does the Computed Tomography Hounsfield Units Change Predict Response to Perioperative Chemotherapy in Patients with Gastric Adenocarcinoma	22
Ribosomal protein L22 like 1: a promising biomarker for lung adenocarcinoma	21
Study on the mechanism of gracillin inhibiting the proliferation of lung cancer NCI-H1299 cells based on MAPK signaling pathway	21
WTAP-Mediated N6-Methyladenosine Modification Promotes Gastric Cancer Progression by Regulating MAP2K6 Expression	20
TYMS Enhances Colorectal Cell Antioxidant Capacity Via the KEAP1-NRF2 Pathway to Resist Ferroptosis	20
Lactate Metabolism Subtypes Analysis Reveals CCDC80 as a Novel Prognostic Biomarker in Gastric Cancer	19
Effectiveness and Safety of Chinese Herbal Injections Combined with SOX Chemotherapy Regimens for Advanced Gastric Cancer: a Bayesian Network Meta-Analysis	19
Downregulation of AKT/mTOR signaling pathway for Salmonella-mediated autophagy in human anaplastic thyroid cancer	19
LncRNA AC099850.3 promotes hepatocellular carcinoma proliferation and invasion through PRR11/PI3K/AKT axis and is associated with patients prognosis	18
Prognostic significance and potential association between ALDOA and ENO1 in gastric cancer	18
Lymph Node Ratio (LNR) Discriminates Prognostication in pN1a-b and pN2 Stage-III Colon Cancer	17
A Comprehensive Analysis of the Prognostic, Immunological and Diagnostic Role of CCNF in Pan-cancer	17
DDX21 Interacts with WDR5 to Promote Colorectal Cancer Cell Proliferation by Activating CDK1 Expression	17
Targeting ESM1/ VEGFα signaling axis: a promising therapeutic avenue for angiogenesis in cervical squamous cell carcinoma	17
Prognostic signature and immune efficacy of m¹A-, m⁵C-, m⁶A-, m⁷G-, and DNA methylation-related regulators in hepatocellular carcinoma	17
Zinc-α2-glycoprotein 1 promotes EMT in colorectal cancer by filamin A mediated focal adhesion pathway: Erratum	16
Correlation Between Messenger RNA Expression and Clinicopathological Features of Breast Cancer: A systematic review	16
Analysis of Aldehyde Dehydrogenase 2 as a Prognostic Marker Associated with Immune Cell infiltration and Chemotherapy Efficacy in Head and Neck Squamous Cell Carcinoma	16
Prognostic significance of BRCA1 and BRCA2 methylation status in circulating cell-free DNA of Pancreatic Cancer patients	16
Acting mechanism and clinical significance of hsa_circ_0005927 in the invasion and metastasis of gastric cancer	16
Exploring the evolving roles and clinical significance of circRNAs in head and neck squamous cell carcinoma	16
Evaluation of ENG/CD105 expression, methylation, immuno-response, and cordycepin (CD) regulation as a novel biomarker of breast invasive carcinoma (BRCA)	16

Fluoxetine as a Potential Therapeutic Agent for Inhibiting Melanoma Brain and Lung Metastasis: Induction of Apoptosis, G0/G1 Cell Cycle Arrest, and Disruption of Autophagy Flux	16
Biomarkers for predicting the efficacy of immune checkpoint inhibitors	16
C. tropicalis promotes CRC by down-regulating tumor cell-intrinsic PD-1 receptor via autophagy	16
Impact of tissue inhibitor of metalloproteinases-3 genetic variants on clinicopathological characteristics of urothelial cell carcinoma	16
Characteristics and function of the gut microbiota in patients with rectal neuroendocrine tumors	16
A Novel Competing Endogenous RNA Network Reveals Potential Mechanisms and Biomarkers of Chemoresistance in Lung Adenocarcinoma	16
BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53	16
Immunomodulatory Effect of Traditional Chinese Medicine Combined with Systemic Therapy on Patients with Liver Cancer: A Systemic Review and Network Meta-analysis	15
Anisomycin has the potential to induce human ovarian cancer stem cell ferroptosis by influencing glutathione metabolism and autophagy signal transduction pathways	15
Overexpression of TC2N is associated with poor prognosis in gastric cancer: Erratum	15
Establishment and bioinformatics analysis of a four-miRNA prognostic signature for pleural mesothelioma	15
CRTC2 promotes paclitaxel resistance by inducing autophagy in ovarian cancer in part via the PI3K-AKT signaling axis	15
Targeting the BMI1-Noxa axis by Dioscin induces apoptosis in oral squamous cell carcinoma cells	15
Lipid metabolic reprogramming by traditional Chinese medicine and its role in effective cancer therapy	15
NEDD1 Promotes the Development of Lung Adenocarcinoma and Can be Used as a Prognostic Marker	15
HECW2 promotes the progression and chemoresistance of colorectal cancer via AKT/mTOR signaling activation by mediating the ubiquitin-proteasome degradation of lamin B1	15
Construction and Validation of a Gastric Cancer Diagnostic Model based on Blood Groups and Tumor Markers	15
Establishment and Validation of a Peroxisome-related Gene Signature for Prognostic Prediction and Immune Distinction in Hepatocellular Carcinoma	15
circROBO1 promotes prostate cancer growth and enzalutamide resistance via accelerating glycolysis	15
In Silico Analysis Uncovers FOXA1 as a Potential Biomarker for Predicting Neoadjuvant Chemotherapy Response in Fine-Needle Aspiration Biopsies	14
Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment	14
Prognostic Value of Lymph Node Necrosis at Different N Stages in Patients with Nasopharyngeal Carcinoma	14
Assessment the value of Pyroptosis-Associated Gasdermin family genes in hepatocellular carcinoma: A Multi-Omics Comprehensive Analysis	14
Cytokeratin Expression Pattern in Human Endometrial Carcinomas and Lymph Nodes Micrometastasis: a Mini-review	14
Impact of PIK3CA Mutations on the Clinical Benefits of CDK 4/6 Inhibitors in HR+/HER2- Advanced Breast Cancer: An Updated Pairwise and Network Meta-Analysis	14
LncRNA SNHG1 acts as a ceRNA for miR-216a-3p to regulate TMBIM6 expression in esophageal squamous cell carcinoma	14
Correspondence on “Robotic radical hysterectomy for cervical cancer: current trends and controversies”	14
Aspartate β-hydroxylase Regulates Expression of Ly6 Genes	14
Pan-Cancer Analysis Reveals SOX2 as a Promising Prognostic and Immunotherapeutic Biomarker Across Various Cancer Types, Including Pancreatic Cancer	14
Early detection of colorectal cancer somatic mutations using cfDNA liquid biopsies in a murine carcinogenesis model	14
3BDO inhibits the proliferation, epithelial-mesenchymal transition (EMT), and stemness via suppressing survivin in human glioblastoma cells	14
Screening of Hub Genes and Therapeutic Drugs in Cervical Cancer Using Integrated Bioinformatics Analysis	14
A comparative study of efficacy and safety of transarterial chemoembolization with CalliSpheres and conventional transarterial chemoembolization in treating unresectable intrahepatic cholangiocarcinom	14
Recent Advancement of PD-L1 Detection Technologies and Clinical Applications in the Era of Precision Cancer Therapy	14
Nanoformulation of Paclitaxel: Exploring the Cyclodextrin / PLGA Nano Delivery Carrier to Slow Down Paclitaxel Release, Enhance Accumulation in Vivo	14
Targeted regulation of miR-154-5p/Cullin2 pathway by hsa_circ_TRIM22 in promoting human papillomavirus 16 positive cervical cancer progression	14
The correlation and role analysis of SLC30A1 and SLC30A10 in cervical carcinoma	14
High CD204⁺ tumor-associated macrophage density predicts a poor prognosis in patients with clear cell renal cell carcinoma	14
Impact of the number of lymph node dissections and a novel risk stratification on the prognosis in elderly locally advanced esophageal adenocarcinoma	14
System Analysis Identifies MYBL2 As a Novel Oncogene Target for Metastatic Prostate Cancer	14
LASS2 impairs proliferation of glioma stem cells and migration and invasion of glioma cells mainly via inhibition of EMT and apoptosis promotion	14
Important functions and molecular mechanisms of aquaporins family on respiratory diseases: potential translational values	14
Wnt5a-mediated autophagy promotes radiation resistance of nasopharyngeal carcinoma	14
SETD2 and EZH2: Two epigenetic drivers of prostate cancer	14
Phase 1 trial of HS006, a recombinant human-mouse chimeric anti-CD20 monoclonal antibody to treat CD20 positive B-cell non-Hodgkin's lymphoma in China	13
The Genetic Causal Effect of Autoimmune Diseases on pan-Cancers: Evidence from Mendelian Randomization	13
Multi-omics analysis reveals lysosome-associated molecular subtype characterization and prognostic modeling system in lung adenocarcinoma	13
Capsaicin and Cold exposure promote EMT-mediated premetastatic niche formation to facilitate colorectal cancer metastasis	13
Characteristics of m⁶A-related LncRNAs in breast cancer as prognostic biomarkers and immunotherapy	13
Prognostic Impact of Ectopic Fat Deposition within Psoas Muscle in Stage IV Gastric Cancer Patients Undergoing Systemic Chemotherapy	13
Simultaneous Resection for Colorectal and Liver Metastases, new equipment and personalized medicine	13
Urinary Dysfunction: Frequency, Risk factors, and Interventions in patients with Cancer during Acute Inpatient Rehabilitation	13
HOXC-AS1 and EZH2 interaction increase HOXC9 expression and promote the malignant transformation of oral leukoplakia	13
Mir-454-3p induced WTX deficiency promotes hepatocellular carcinoma progressions through regulating TGF-β signaling pathway	13
Genomic analysis of hypoxia and mitophagy related genes with prognosis and characterization of the immune microenvironment in LUAD	13
Tripartite motif containing 69 elicits ERK2-dependent EYA4 turnover to impart pancreatic tumorigenesis	13
Establishing and Validating a novel Prognostic Model in the Initial Diagnosis of Non-small Cell Lung Cancer with Bone Metastases	13
RNF114 Interacts with EWSR1 to Regulate VEGFR2 in HER2-positive Breast Cancer	13
AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H₂O₂ Activation of Syk/PI3K/Akt Signaling Axis	13
Focal Boundary Dice: Improved Breast Tumor Segmentation from MRI Scan	13
Anticancer Efficacy and Mechanisms of a Dual Targeting of Norepinephrine Transporter and Thyrointegrin αvβ3 Antagonist in Neuroblastoma	13
The Association of ERCC1 and ERCC5 Polymorphisms with Lung Cancer Risk in Han Chinese	13
An insulin growth factor-I/II-neutralizing monoclonal antibody in combination with epidermal growth factor receptor inhibitors potently inhibits tumor cell growth	12
A Novel Tumor-Associated Neutrophil-Related Risk Signature Based on Single-Cell and Bulk RNA-Sequencing Analyses Predicts the Prognosis and Immune Landscape of Breast Cancer	12
LINC00630 promotes cholangiocarcinoma cell proliferation, migration and invasion by mediating the miR-199a/FGF7 axis	12
Enhanced Efficacy of Chemotherapy by Addition of Immune Checkpoint Inhibitors in Stage IV Large Cell Neuroendocrine Carcinoma of the Lung: A Real-World Analysis	12
Risk Prediction of Myelosuppression Following First-line Chemotherapy in Colorectal Cancer	12
Participation of Increased Circulating MAIT Cells in Lung Cancer: a Pilot Study	12
Impacts of Cigarette Smoking on the Tumor Immune Microenvironment in Esophageal Squamous Cell Carcinoma	12
RBM10 inhibits pancreatic cancer development by suppressing immune escape through PD-1 expression	12
Causal relationship between immune cells and hepatocellular carcinoma: a Mendelian randomisation study	12
Blockade of spinal dopamine D1/D2 receptor heteromers by levo-Corydalmine suppressed calcium signaling cascade in spinal neurons to alleviate bone cancer pain in rats	12
Identification and analysis of a prognostic ferroptosis and iron-metabolism signature for esophageal squamous cell carcinoma	12
Tumor Cell-derived Extracellular Vesicles in Modulating Phenotypes and Immune Functions of Macrophages: Mechanisms and Therapeutic Applications	12
Glycolytic Metabolic Remodeling by the Truncate of Glioma-Associated Oncogene Homolog 1 in Triple-Negative Breast Cancer Cells	12
Accuracy analysis of different dose calculation algorithms for locally advanced pancreatic cancer stereotactic body radiotherapy	12
FSCN1 acts as a promising therapeutic target in the blockade of tumor cell motility: a review of its function, mechanism, and clinical significance	12
Causal association of plasma lipidome with lung carcinoma and mediating role of inflammatory proteins: evidence from Mendelian randomization analysis	12
Clinicopathological Significances and Prognostic Value of PPFIA4 in Colorectal Cancer	12
Propofol reduces breast cancer cell stemness via FOXO3/SOX2 axis	12

DPF2 overexpression correlates with immune infiltration and dismal prognosis in hepatocellular carcinoma	12
Oncolytic Virus Therapy in a New Era of Immunotherapy, Enhanced by Combination with Existing Anticancer Therapies: Turn up the Heat!	12
Orlistat Induces Ferroptosis in Pancreatic Neuroendocrine Tumors by Inactivating the MAPK Pathway	12
Cholesterol metabolism and its implication in glioblastoma therapy	11
Prognostic role of immunohistochemical PTEN (phosphatase and tensin homolog) expression and PTEN (rs701848) genotypes among Egyptian patients with different stages of colorectal cancer	11
Experimental Validation and Multi-omics Analysis Identified ARPC1A as a Novel Oncogene and Potential Therapeutic Target in Glioblastoma	11
Identification and validation of a novel apoptosis-related prognostic risk score model for lung adenocarcinoma	11
Real-world experience of safety and effectiveness of regorafenib for treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumors, and hepatocellular carcinoma: a post-marketing	11
Melatonin Potentiates Sensitivity to 5-Fluorouracil in Gastric Cancer Cells by Upregulating Autophagy and Downregulating Myosin Light-Chain Kinase	11
Integrin subunit β4 drives the aggressiveness of papillary thyroid carcinoma by enhancing MMP14 expression through transcription factor RUNX1 pathway	11
The Mitochondrial Protein C1QBP Promotes Hepatocellular Carcinoma Progression by Enhancing Cell Survival, Migration and Invasion	11
Abnormal spindle-like microcephaly-associated protein (ASPM) contributes to the progression of Lung Squamous Cell Carcinoma (LSCC) by regulating CDK4: Erratum	11
The Association between Pretreatment anemia and Overall Survival in Advanced Non-small Cell lung Cancer: A Retrospective Cohort Study Using Propensity Score Matching	11
KMT2A Mutations and High Prevalence of dMMR-associated Mutational Signatures as Prognostic Indicators in Metastatic Colorectal Cancer	11
APEX1 predicts poor prognosis of gallbladder cancer and affects biological properties of CD133⁺ GBC-SD cells via upregulating Jagged1	11
Somatic mutation and expression of BAP1 in hepatocellular carcinoma: an indicator for ferroptosis and immune checkpoint inhibitor therapies	11
The effect of radiotherapy time and dose on acute hematologic toxicity during concurrent postoperative chemoradiotherapy for early high-risk cervical cancer	11
Enhanced Multimodal Brain Tumor Classification in MR Images using 2D ResNet as backbone with Explicit Tumor Size Information	11
Addition of Bevacizumab to Vinorelbine-Platinum combination is efficacious in Heavily Pretreated HER2-Negative Metastatic Breast Cancer	11
Prognostic value of gender and primary tumor location in metastatic colon cancer	11
Identification of M2 macrophage markers for predicting outcome and therapeutic response in osteosarcoma: Integrated analysis of single-cell and bulk RNA-sequencing	11
Programmed cell death-index (PCDi) as a prognostic biomarker and predictor of drug sensitivity in cervical cancer: a machine learning-based analysis of mRNA signatures	11
Overexpression of pressure-responsive miRNA-5703 inhibits pressure-induced growth and metastasis of liver cancer	11
Deubiquitinase OTUD7B is a potential prognostic biomarker in diffuse large B-cell lymphoma	11
Senescence Reprogramming by MTHFD2 Deficiency Facilitates Tumor Progression	11
Characterization of Inflammatory Breast Cancer in Hispanic Women from Puerto Rico	11
Network pharmacology and biological verification of morusin's therapeutic mechanisms in inhibiting nasopharyngeal carcinoma growth	10
Artificial Intelligence Model for a Distinction between Early-Stage Gastric Cancer Invasive Depth T1a and T1b	10
Spatial and Single-Cell Investigations Illuminate Theragnostic value and Immune Landscape of Mitochondrial Dynamin-Like GTPase in Breast Cancer	10
Tripartite motif-containing 28 (TRIM28) expression and cordycepin inhibition in progression, prognosis, and therapeutics of patients with breast invasive carcinoma	10
The Function and Regulation of SAPCD2 in Physiological and Oncogenic Processes	10
Expression of Prostate-specific Membrane Antigen (PSMA) in Papillary Renal Cell Carcinoma - Overview and Report on a Large Multicenter Cohort	10
RPL17 Promotes Colorectal Cancer Proliferation and Stemness through ERK and NEK2/β-catenin Signaling Pathways	10
Integrated bioinformatics analysis and experimental validation to understand tryptophan metabolism-related genes in hepatocellular carcinoma	10
Overcoming the limitations of immunotherapy in pancreatic ductal adenocarcinoma: Combining radiotherapy and metabolic targeting therapy	10
Metformin May Improve Intestinal Mucosal Barrier Function and Help Prevent and Reverse Colorectal Cancer in Mice	10
PHGDH is Key to a Prognostic Multigene Signature and a Potential Therapeutic Target in Acute Myeloid Leukemia	10
JS-K activates G2/M checkpoints through the DNA damage response and induces autophagy via CAMKKβ/AMPKα/mTOR pathway in bladder cancer cells	10
Causal association of smoking, blood lipids, and bladder cancer: Insights from a multivariable and mediation mendelian randomization investigation	10
Advances in Radiomics Research for Endometrial Cancer: A Comprehensive Review	10
Investigating the mechanism and the effect of aquaporin 5 (AQP5) on the self-renewal capacity of gastric cancer stem cells	10
Long noncoding RNA DSCR8 promotes the proliferation of liver cancer cells and inhibits apoptosis via the miR-22-3p/ARPC5 Axis	10
Comprehensive analysis reveals MCM4 as a biomarker for guiding therapies and immunomodulatory role in skin cutaneous melanoma	10
NUPR1 contributes to endocrine therapy resistance by modulating BIRC5 expression and inducing luminal B-ERBB2⁺ subtype-like characteristics in estrogen receptor-positive breast cancer cells	10
The functional role of Pescadillo ribosomal biogenesis factor 1 in cancer	10
The transcription factor ZNF248 promotes colorectal cancer metastasis by binding to ZEB1	10
PLK4 is a key molecule in the formation of PGCCs and promotes invasion and migration of progeny cells derived from PGCCs	10
Research progress on molecular mechanism of liver metastasis of gastric cancer and treatment with traditional Chinese medicine	10
Cucurbitacin I inhibits the proliferation of pancreatic cancer through the JAK2/STAT3 signalling pathway in vivo and in vitro	10
Integrative Analysis of Histone Deacetylases Reveals the Potential Role and Prognostic Value of HDAC7 in Hepatocellular Carcinoma	10
Integrative Multi-Omics Analysis Reveals Key Metabolic Regulators and Prognostic Biomarkers in Pediatric and Adult Thyroid Cancer	10
Validation the role of desmocollin-2 in osteosarcoma based on single cell and bulk RNA seq and experimental analyses	9
Important Role of Intestinal Microbiota in Chemotherapy-induced Diarrhea and Therapeutics	9
Promoter Methylation-Mediated NPTX2 Silencing Promotes Tumor Growth in Human Prostate Cancer	9
Streptococcus mutans promotes tumor progression in oral squamous cell carcinoma	9
Green walnut husk extracts Proliferation and Migration in Gastric Cancer	9
Construction of a novel radiosensitivity- and ferroptosis-associated gene signature for prognosis prediction in gliomas	9
The Role MicroRNA-135a in Suppressing Tumor Growth in Kidney Cancer Through the Regulation of Phosphoprotein Phosphatase2A and the Activation of the AKT and ERK1/2 Signaling Pathways	9
Pharmacokinetics and Safety of Multiple-Dose Alpelisib in Participants with Moderate or Severe Hepatic Impairment: A Phase 1, Open-Label, Parallel Group Study	9
METTL3 Facilitates Tumor Progression by COL12A1/MAPK Signaling Pathway in Esophageal Squamous Cell Carcinoma	9
Identification of glutamine metabolism-related gene signature to predict colorectal cancer prognosis	9
SEMA4A promotes prostate cancer invasion: involvement of tumor microenvironment	9
Knowledge and awareness of warning signs about Lung cancer among Pharmacy and Nursing undergraduates in Riyadh, Saudi Arabia - an observational study	9
Multidimensional analysis of TMEM132A in pan-cancer: unveiling its potential as a biomarker for treatment response prediction	9
A Positive Feedback Loop of E2F4-Mediated Activation of MNX1 Regulates Tumour Progression in Colorectal Cancer	9
Mitochondrial Gene Scoring System: Predicting Prognosis and Precision Therapy for TACE Non-Response in Hepatocellular Carcinoma Patients	9
CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway	9
lncRNA VIM-AS1 acts as a prognostic biomarker and promotes apoptosis in lung adenocarcinoma	9
MicroRNA-506-3p inhibits ovarian cancer metastasis by down-regulating the expression of EZH2	9
Targeting NEAT1 Affects the Sensitivity to PARPi in Serous Ovarian Cancer by Regulating the Homologous Recombination Repair Pathway	9
Paxillin promotes the invasion and migration of polyploid giant cancer cells with daughter cells after arsenic trioxide treatment by regulating the expression of cathepsin B/D	9
A nomogram prediction model based on clinicopathological combined radiological features for metachronous liver metastasis of colorectal cancer	9
Sinapine Thiocyanate Inhibits the Proliferation and Mobility of Pancreatic Cancer Cells by Up-Regulating GADD45A	9
Brucine suppresses proliferation and promotes apoptosis of human cholangiacarcinoma cells via the inhibition of COX2 expression	9
PYCR1: A Potential Prognostic Biomarker in Pancreatic Ductal Adenocarcinoma	9
Triptolide suppresses melanoma cell growth in vitro and in vivo through the Src-ERK signaling pathway	9
Third generation vs first generation EGFR-TKIs in the first line treatment for EGFR-mutated locally advanced or metastatic non-small cell lung cancer: a meta-analysis based on randomized controlled tr	9
Insights into Structure and Function of Growth Arrest Specific 2 (GAS2)	9
Matrix stiffness regulates NPC invasiveness by modulating a mechanoresponsive TRPV4-Nox4-IL-8 signaling axis	9
Current status and progress of the development of prostate cancer vaccines	9
Possible non-linear relation between prostate specific antigen and vitamin D: a machine learning study based on cross-section data	9
Characteristics of Non-mass Enhancement in Contrast-enhanced Breast MRI and Associations with Malignancy	9
Development of a Novel four-gene Model for Monitoring the Progression from Metabolic Dysfunction-associated Steatotic Liver Disease to Hepatocellular Carcinoma in Males	8
A nomogram based on plasma HSP90α and NLR for predicting prognosis in advanced gastric cancer patients treated with PD-1 inhibitors	8
Construction of a Prognostic Model for Cervical Cancer Related to lncRNA Based on Differential Co-expression Network and Functional Study of Key Gene EGFR-AS1	8
Analysis of m⁶A-related lncRNAs for prognostic and immunotherapeutic response in hepatocellular carcinoma	8
Impact of carbonic anhydrase 9 gene polymorphism on the progression of colorectal cancer	8
The inhibitory effect of KIAA1456 on the proliferation and metastasis of epithelial ovarian cancer through SSX1 and AKT signaling pathway	8
Detection of Extracellular Vesicle-Derived RNA as Potential Prostate Cancer Biomarkers: Role of Cancer-type SLCO1B3 and ABCC3	8
Web-based prediction models for predicting overall survival and cancer specific survival in lung metastasis of patients with thyroid cancer: a study based on the SEER database and a Chinese cohort	8
Knowledge mapping and current trends of global research on snoRNA in the field of cancer	8
From Spatial Patterns to Prognosis: Decoding Single-Cell Architecture in Cancer with Hyperplex Immunofluorescence Imaging	8
Is robotic surgery beneficial for the treatment of endometrial cancer? A comparison with conventional laparoscopic surgery	8
Preliminary study on the active substances and cellular pathways of lactic acid bacteria for colorectal cancer treatment	8
Integrated Multi-omics Data Analysis and In Vitro Validation Reveal the Crucial Role of Glycogen Metabolism in Gastric Cancer	8