OOIR: Observatory of International Research

Papers

(The median citation count of Molecular Medicine Reports is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Protective role of taurine against oxidative stress (Review)	122
Cartilage tissue engineering: From proinflammatory and anti‑inflammatory cytokines to osteoarthritis treatments (Review)	93
HIF‑1α in myocardial ischemia‑reperfusion injury (Review)	70
Acute spinal cord injury: Pathophysiology and pharmacological intervention (Review)	70
Exosomes from miR-29a-modified adipose-derived mesenchymal stem cells reduce excessive scar formation by inhibiting TGF-β2/Smad3 signaling	53
Effects and molecular mechanism of pachymic acid on ferroptosis in renal ischemia reperfusion injury	49
circRNA‑0006896‑miR1264‑DNMT1 axis plays an important role in carotid plaque destabilization by regulating the behavior of endothelial cells in atherosclerosis	49
M2‑like tumour‑associated macrophage‑secreted IGF promotes thyroid cancer stemness and metastasis by activating the PI3K/AKT/mTOR pathway	44
Advanced glycation end products promote osteoporosis by inducing ferroptosis in osteoblasts	41
Metformin induces apoptosis and inhibits migration by activating the AMPK/p53 axis and suppressing PI3K/AKT signaling in human cervical cancer cells	41
Sarcopenia, frailty and type 2 diabetes mellitus (Review)	40
Advances in the application of molecular diagnostic techniques for the detection of infectious disease pathogens (Review)	39
Multi‑faceted role of cancer‑associated adipocytes in the tumor microenvironment (Review)	38
Application of nanotechnology in drug delivery systems for respiratory diseases (Review)	37
LINC00861 inhibits the progression of cervical cancer cells by functioning as a ceRNA for miR‑513b‑5p and regulating the PTEN/AKT/mTOR signaling pathway	37
BMP2 induces hMSC osteogenesis and matrix remodeling	36
Wnt/β‑catenin signaling: Causes and treatment targets of drug resistance in colorectal cancer (Review)	33
Role of hypoxia inducible factor-1 in cancer stem cells (Review)	33
lncRNA PVT1 modulates NLRP3‑mediated pyroptosis in septic acute kidney injury by targeting miR‑20a‑5p	32
Molecular insights into the benefits of nicotine on memory and cognition (Review)	32
Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR‑mediated autophagy	31
COVID‑19 vaccination and IgG and IgA antibody dynamics in healthcare workers	31
Naringin ameliorates memory deficits and exerts neuroprotective effects in a mouse model of Alzheimer's disease by regulating multiple metabolic pathways	30
Allisartan isoproxil attenuates oxidative stress and inflammation through the SIRT1/Nrf2/NF‑κB signalling pathway in diabetic cardiomyopathy rats	30
Biological and neurological activities of astaxanthin (Review)	30

FABP4 knockdown suppresses inflammation, apoptosis and extracellular matrix degradation in IL-1β-induced chondrocytes by activating PPARγ to regulate the NF-κB signaling pathway	29
Τelomerase inhibitors and activators in aging and cancer: A systematic review	29
Relationship between the pyroptosis of fibroblast‑like synoviocytes and HMGB1 secretion in knee osteoarthritis	29
Salusin‑β participates in high glucose‑induced HK‑2 cell ferroptosis in a Nrf‑2‑dependent manner	29
Hsa‑circRNA‑G004213 promotes cisplatin sensitivity by regulating miR‑513b‑5p/PRPF39 in liver cancer	28
Ginsenoside Re exhibits neuroprotective effects by inhibiting neuroinflammation via CAMK/MAPK/NF‑κB signaling in microglia	28
circSAMD4A participates in the apoptosis and autophagy of dopaminergic neurons via the miR‑29c‑3p‑mediated AMPK/mTOR pathway in Parkinson's disease	28
Interplay of retinol binding protein 4 with obesity and associated chronic alterations (Review)	27
Curcumin attenuates lncRNA H19‑induced epithelial‑mesenchymal transition in tamoxifen‑resistant breast cancer cells	27
Cytotoxic effect of CLL‑1 CAR‑T cell immunotherapy with PD‑1 silencing on relapsed/refractory acute myeloid leukemia	27
Hydrogen sulfide ameliorates doxorubicin‑induced myocardial fibrosis in rats via the PI3K/AKT/mTOR pathway	26
Lidocaine attenuates hypoxia/reoxygenation‑induced inflammation, apoptosis and ferroptosis in lung epithelial cells by regulating the p38 MAPK pathway	26
Ginsenoside Rg1 improves cognitive capability and affects the microbiota of large intestine of tree shrew model for Alzheimer's disease	26
miR‑214 ameliorates sepsis‑induced acute kidney injury via PTEN/AKT/mTOR‑regulated autophagy	26
lncRNA‑MALAT1 promotes high glucose‑induced H9C2 cardiomyocyte pyroptosis by downregulating miR‑141‑3p expression	26
Ferroptosis inhibitor ferrostatin‑1 alleviates homocysteine‑induced ovarian granulosa cell injury by regulating TET activity and DNA methylation	26
Radioprotective countermeasures for radiation injury (Review)	25
Erastin‑induced ferroptosis causes physiological and pathological changes in healthy tissues of mice	25
Functions of circular RNAs in bladder, prostate and renal cell cancer (Review)	25
Roles of α‑synuclein in gastrointestinal microbiome dysbiosis‑related Parkinson's disease progression (Review)	25
Serum long non‑coding RNA NNT‑AS1 protected by exosome is a potential biomarker and functions as an oncogene via the miR‑496/RAP2C axis in colorectal cancer	25
Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma	24
Long non‑coding RNA MEG3 inhibits cell migration and invasion of non‑small cell lung cancer cells by regulating the miR‑21‑5p/PTEN axis	23
Curcumin ameliorates DSS‑induced colitis in mice by regulating the Treg/Th17 signaling pathway	23
circ-PRKCI targets miR-1294 and miR-186-5p by downregulating FOXK1 expression to suppress glycolysis in hepatocellular carcinoma	23
Age affects the paracrine activity and differentiation potential of human adipose‑derived stem cells	23
Aspirin attenuates liver fibrosis by suppressing TGF‑β1/Smad signaling	23
Ginsenoside Rk1 protects human melanocytes from H₂O₂‑induced oxidative injury via regulation of the PI3K/AKT/Nrf2/HO‑1 pathway	23
Astaxanthin induces NADPH oxidase activation and receptor‑interacting protein kinase 1‑mediated necroptosis in gastric cancer AGS cells	22
Transcriptional activation of ENPP2 by FoxO4 protects cardiomyocytes from doxorubicin‑induced toxicity	22
Crosstalk between NK cells and hepatic stellate cells in liver fibrosis (Review)	22
Apatinib suppresses the migration, invasion and angiogenesis of hepatocellular carcinoma cells by blocking VEGF and PI3K/AKT signaling pathways	22
Systemic inflammatory response syndrome is triggered by mitochondrial damage (Review)	22
Ginsenoside Rg1 ameliorates aging‑induced liver fibrosis by inhibiting the NOX4/NLRP3 inflammasome in SAMP8 mice	22
The potential role and trend of HIF‑1α in intervertebral disc degeneration: Friend or foe? (Review)	21
NLRP3 inflammasome in sepsis (Review)	21
Circulating microRNA‑135a‑3p in serum extracellular vesicles as a potential biological marker of non‑alcoholic fatty liver disease	21
Ferroptosis in hepatic ischemia‑reperfusion injury: Regulatory mechanisms and new methods for therapy (Review)	21
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway	21
HIF‑1α in cerebral ischemia (Review)	21
Benchmarking of next and third generation sequencing technologies and their associated algorithms for de novo genome assembly	21
Dexmedetomidine alleviates early brain injury following traumatic brain injury by inhibiting autophagy and neuroinflammation through the ROS/Nrf2 signaling pathway	21
Tanshinone IIA attenuates heart failure via inhibiting oxidative stress in myocardial infarction rats	21
Inhibitory role of ginsenoside Rb2 in endothelial senescence and inflammation mediated by microRNA‑216a	21
Resveratrol affects the expression of uric acid transporter by improving inflammation	21
SIRT6‑specific inhibitor OSS‑128167 exacerbates diabetic cardiomyopathy by aggravating inflammation and oxidative stress	20
Melatonin inhibits proliferation and viability and promotes apoptosis in colorectal cancer cells via upregulation of the microRNA-34a/449a cluster	20
All‑trans retinoic acid promotes macrophage phagocytosis and decreases inflammation via inhibiting CD14/TLR4 in acute lung injury	20
A combination of PD‑1/PD‑L1 inhibitors: The prospect of overcoming the weakness of tumor immunotherapy (Review)	20
Resveratrol alleviates oxygen/glucose deprivation/reoxygenation‑induced neuronal damage through induction of mitophagy	20

Tanshinone IIA regulates microRNA‑125b/foxp3/caspase‑1 signaling and inhibits cell viability of nasopharyngeal carcinoma	20
Dimethyl itaconate inhibits LPS‑induced microglia inflammation and inflammasome‑mediated pyroptosis via inducing autophagy and regulating the Nrf‑2/HO‑1 signaling pathway	20
Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway	20
Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects	20
Current treatment strategies for COVID‑19 (Review)	20
Ginsenoside Rh2 stimulates the production of mitochondrial reactive oxygen species and induces apoptosis of cervical cancer cells by inhibiting mitochondrial electron transfer chain complex	20
lncRNA FGD5‑AS1 promotes breast cancer progression by regulating the hsa‑miR‑195‑5p/NUAK2 axis	20
GAS5 regulates diabetic cardiomyopathy via miR‑221‑3p/p27 axis‑associated autophagy	20
Hypoxia‑induced lactate dehydrogenase A protects cells from apoptosis in endometriosis	20
Buyang Huanwu Decoction promotes neurogenesis via sirtuin 1/autophagy pathway in a cerebral ischemia model	20
S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway	20
IL‑33/ST2 promotes the malignant progression of gastric cancer via the MAPK pathway	20
Polygonatum sibiricum F. Delaroche polysaccharide ameliorates HFD‑induced mouse obesity via regulation of lipid metabolism and inflammatory response	20
Hydrogen sulfide attenuates renal I/R‑induced activation of the inflammatory response and apoptosis via regulating Nrf2‑mediated NLRP3 signaling pathway inhibition	20
Reoxygenation induces reactive oxygen species production and ferroptosis in renal tubular epithelial cells by activating aryl hydrocarbon receptor	20
Procyanidin B2 inhibits lipopolysaccharide‑induced apoptosis by suppressing the Bcl‑2/Bax and NF‑κB signalling pathways in human umbilical vein endothelial cells	20
lncRNA GAS5 promotes pyroptosis in COPD by functioning as a ceRNA to regulate the miR‑223‑3p/NLRP3 axis	19
Fine particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice	19
MicroRNA‑223‑induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways	19
Identification and validation of EPHX2 as a prognostic biomarker in hepatocellular carcinoma	19
Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice	19
Novel insights into di‑(2‑ethylhexyl)phthalate activation: Implications for the hypothalamus‑pituitary‑thyroid axis	19
Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice	19
Radiation‑induced dysfunction of energy metabolism in the heart results in the fibrosis of cardiac tissues	19
Mangiferin inhibits cell migration and angiogenesis via PI3K/AKT/mTOR signaling in high glucose‑ and hypoxia‑induced RRCECs	19
Sacubitril/valsartan (LCZ696) reduces myocardial injury following myocardial infarction by inhibiting NLRP3‑induced pyroptosis via the TAK1/JNK signaling pathway	19
Claudin 6: Therapeutic prospects for tumours, and mechanisms of expression and regulation (Review)	19
Knockdown of circ‑PVT1 inhibits the progression of lung adenocarcinoma and enhances the sensitivity to cisplatin via the miR‑429/FOXK1 signaling axis	19
Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis	19
Total flavonoids of Rhizoma drynariae ameliorate steroid‑induced avascular necrosis of the femoral head via the PI3K/AKT pathway	18
CBX2 depletion inhibits the proliferation, invasion and migration of gastric cancer cells by inactivating the YAP/β-catenin pathway	18
Immature granulocytes: Innovative biomarker for SARS‑CoV‑2 infection	18
miR‑143‑3p inhibits endometriotic stromal cell proliferation and invasion by inactivating autophagy in endometriosis	18
Development and characterization of TrMab‑6, a novel anti‑TROP2 monoclonal antibody for antigen detection in breast cancer	18
LY‑294002 enhances the chemosensitivity of liver cancer to oxaliplatin by blocking the PI3K/AKT/HIF‑1α pathway	18
Dendrobium mixture attenuates renal damage in rats with diabetic nephropathy by inhibiting the PI3K/Akt/mTOR pathway	18
Lycium barbarum polysaccharide protects ARPE‑19 cells against H₂O₂‑induced oxidative stress via the Nrf2/HO‑1 pathway	18
κ‑opioid receptor agonist, U50488H, inhibits pyroptosis through NLRP3 via the Ca²⁺/CaMKII/CREB signaling pathway and improves synaptic plasticity in APP/PS1 mice	18
Shikonin inhibits the Warburg effect, cell proliferation, invasion and migration by downregulating PFKFB2 expression in lung cancer	18
Role of indoleamine 2,3-dioxygenase in ischemia-reperfusion injury of renal tubular epithelial cells	18
miR‑34a increases inflammation and oxidative stress levels in patients with necrotizing enterocolitis by downregulating SIRT1 expression	18
Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species	18
Ulinastatin protects against sepsis‑induced myocardial injury by inhibiting NLRP3 inflammasome activation	18
Circular RNA ABCB10 promotes cell proliferation and invasion, but inhibits apoptosis via regulating the microRNA‑1271‑mediated Capn4/Wnt/β‑catenin signaling pathway in epithelial ovarian cancer	17
Expression profile and diagnostic value of circRNAs in peripheral blood from patients with systemic lupus erythematosus	17
Knockdown of long non‑coding RNA DDX11‑AS1 inhibits the proliferation, migration and paclitaxel resistance of breast cancer cells by upregulating microRNA‑497 expression	17
B7‑H3 promotes the epithelial‑mesenchymal transition of NSCLC by targeting SIRT1 through the PI3K/AKT pathway	17
Upregulation of CCT3 promotes cervical cancer progression through FN1	17
PPARγ attenuates hepatic inflammation and oxidative stress of non‑alcoholic steatohepatitis via modulating the miR‑21‑5p/SFRP5 pathway	17
miR‑101‑3p negatively regulates inflammation in systemic lupus erythematosus via MAPK1 targeting and inhibition of the NF‑κB pathway	17
Possibility of exosome‑based coronavirus disease 2019 vaccine (Review)	17
Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway	17
miR‑576‑5p promotes epithelial‑to‑mesenchymal transition in colorectal cancer by targeting the Wnt5a‑mediated Wnt/β‑catenin signaling pathway	17
MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo	17
Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes	17
Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury	17
Different roles of matrix metalloproteinase 2 in osteolysis of skeletal dysplasia and bone metastasis (Review)	17
Long non‑coding RNA JPX promotes gastric cancer progression by regulating CXCR6 and autophagy via inhibiting miR‑197	17
lncRNA TUG1 inhibits the cancer stem cell‑like properties of temozolomide‑resistant glioma cells by interacting with EZH2	17
ABT‑737, a Bcl‑2 family inhibitor, has a synergistic effect with apoptosis by inducing urothelial carcinoma cell necroptosis	17
Neuroprotective effect of Ginsenoside Re against neurotoxin‑induced Parkinson's disease models via induction of Nrf2	16
SEC61G is upregulated and required for tumor progression in human kidney cancer	16
Overexpression of Foxc1 ameliorates sepsis‑associated encephalopathy by inhibiting microglial migration and neuroinflammation through the IκBα/NF‑κB pathway	16
Sirt3 promotes the autophagy of HK‑2 human proximal tubular epithelial cells via the inhibition of Notch‑1/Hes‑1 signaling	16
MAPK inhibitors protect against early‑stage osteoarthritis by activating autophagy	16
Gryllus bimaculatus extract protects against lipopolysaccharide and palmitate-induced production of proinflammatory cytokines and inflammasome formation	16
lncRNA SNHG4 promotes cell proliferation, migration, invasion and the epithelial-mesenchymal transition process via sponging miR-204-5p in gastric cancer	16
linc‑ROR facilitates hepatocellular carcinoma resistance to doxorubicin by regulating TWIST1‑mediated epithelial‑mesenchymal transition	16
Effects of miRNAs, lncRNAs and circRNAs on osteoporosis as regulatory factors of bone homeostasis (Review)	16
Knockdown of miR‑205‑5p alleviates the inflammatory response in allergic rhinitis by targeting B‑cell lymphoma 6	16
MicroRNA‑153 attenuates hypoxia‑induced excessive proliferation and migration of pulmonary arterial smooth muscle cells by targeting ROCK1 and NFATc3	16
Regulation of angiogenesis by microRNAs in cancer	16
Association between HO‑1 gene promoter polymorphisms and diseases (Review)	16
Inhibition of chaperone‑mediated autophagy reduces tumor growth and metastasis and promotes drug sensitivity in colorectal cancer	16
Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis	16
lncRNA NEAT1 regulates gastric carcinoma cell proliferation, invasion and apoptosis via the miR‑500a‑3p/XBP‑1 axis	16
H2S regulation of ferroptosis attenuates sepsis‑induced cardiomyopathy	16
Regulation and mechanism of YAP/TAZ in the mechanical microenvironment of stem cells (Review)	16
Non-toxic sulfur inhibits LPS-induced inflammation by regulating TLR-4 and JAK2/STAT3 through IL-6 signaling	15
Naringin induces apoptosis of gastric carcinoma cells via blocking the PI3K/AKT pathway and activating pro‑death autophagy	15

Let‑7b‑5p promotes cell apoptosis in Parkinson's disease by targeting HMGA2	15
lncRNA MIR4435‑2HG promotes the progression of liver cancer by upregulating B3GNT5 expression	15
Role of microRNA‑218‑5p in sevoflurane‑induced protective effects in hepatic ischemia/reperfusion injury mice by regulating GAB2/PI3K/AKT pathway	15
PDGF mediates pulmonary arterial smooth muscle cell proliferation and migration by regulating NFATc2	15
Lycium barbarum polysaccharide protects rats and cardiomyocytes against ischemia/reperfusion injury via Nrf2 activation through autophagy inhibition	15
Lipocalin 2 activates the NLRP3 inflammasome via LPS‑induced NF‑κB signaling and plays a role as a pro‑inflammatory regulator in murine macrophages	15
CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes	15
Triptolide promotes ferroptosis by suppressing Nrf2 to overcome leukemia cell resistance to doxorubicin	15
miR‑139‑5p enhances cisplatin sensitivity in non‑small cell lung cancer cells by inhibiting cell proliferation and promoting apoptosis via the targeting of Homeobox protein Hox‑B2	15
Essential oil ofFoeniculum vulgaresubsp.piperitumfruits exerts an anti‑tumor effect in triple‑negative breast cancer cells	15
Acute glucose fluctuation promotes RAGE expression via reactive oxygen species‑mediated NF‑κB activation in rat podocytes	15
Liquiritigenin attenuates isoprenaline‑induced myocardial fibrosis in mice through the TGF‑β1/Smad2 and AKT/ERK signaling pathways	15
FBXW7 mediates high glucose‑induced SREBP‑1 expression in renal tubular cells of diabetic nephropathy under PI3K/Akt pathway regulation	15
Cyanidin‑3‑O‑β‑glucoside protects against pulmonary artery hypertension induced by monocrotaline via the TGF‑β1/p38 MAPK/CREB signaling pathway	15
Potential impact of GCK, MIR-196A-2 and MIR-423 gene abnormalities on the development and progression of type 2 diabetes mellitus in Asir and Tabuk regions of Saudi Arabia	15
Gasotransmitters in the tumor microenvironment: Impacts on cancer chemotherapy (Review)	15
Silibinin improves nonalcoholic fatty liver by regulating the expression of miR‑122: An in vitro and in vivo study	15
Role of metformin in functional endometrial hyperplasia and polycystic ovary syndrome involves the regulation of MEG3/miR‑223/GLUT4 and SNHG20/miR‑4486/GLUT4 signaling	15
Mental depression: Relation to different disease status, newer treatments and its association with COVID-19 pandemic (Review)	15
Major signaling pathways and key mediators of macrophages in acute kidney injury (Review)	15
MicroRNA‑592 promotes cell proliferation, migration and invasion in colorectal cancer by directly targeting SPARC	14
Baicalin relievesMycoplasma pneumoniaeinfection‑induced lung injury through regulating microRNA‑221 to inhibit the TLR4/NF‑κB signaling pathway	14
Phillygenin inhibits the inflammation and apoptosis of pulmonary epithelial cells by activating PPARγ signaling via downregulation of MMP8	14
Intestinal dysbacteriosis leads to kidney stone disease	14
lncRNA GAS5 regulates angiogenesis by targeting miR‑10a‑3p/VEGFA in osteoporosis	14
MicroRNA‑138‑5p drives the progression of heart failure via inhibiting sirtuin 1 signaling	14
MST1 inhibits the progression of breast cancer by regulating the Hippo signaling pathway and may serve as a prognostic biomarker	14
Primary bile acid activates Egr‑1 expression through the MAPK signaling pathway in gastric cancer	14
HIF‑3α affects preeclampsia development by regulating EVT growth via activation of the Flt‑1/JAK/STAT signaling pathway in hypoxia	14
Ginkgolide B‑induced AMPK pathway activation protects astrocytes by regulating endoplasmic reticulum stress, oxidative stress and energy metabolism induced by Aβ1‑42	14
HK2 is associated with the Warburg effect and proliferation in liver cancer: Targets for effective therapy with glycyrrhizin	14
Atezolizumab alleviates the immunosuppression induced by PD‑L1‑positive neutrophils and improves the survival of mice during sepsis	14
miR‑18a‑5p promotes melanoma cell proliferation and inhibits apoptosis and autophagy by targeting EPHA7 signaling	14
Intrathecal injection of ozone alleviates CCI‑induced neuropathic pain via the GluR6‑NF‑κB/p65 signalling pathway in rats	14
Chidamide induces apoptosis in DLBCL cells by suppressing the HDACs/STAT3/Bcl‑2 pathway	14
circARRDC3 contributes to interleukin‑13‑induced inflammatory cytokine and mucus production in nasal epithelial cells via the miR‑375/KLF4 axis	14
Tacrolimus inhibits insulin release and promotes apoptosis of Min6 cells through the inhibition of the PI3K/Akt/mTOR pathway	14
Berberine inhibits the proliferation, invasion and migration of endometrial stromal cells by downregulating miR‑429	14
Platelet isoform of phosphofructokinase promotes aerobic glycolysis and the progression of non‑small cell lung cancer	14
Circular RNA hsa_circ_0072309 inhibits the proliferation, invasion and migration of gastric cancer cells via inhibition of PI3K/AKT signaling by activating PPARγ/PTEN signaling	14
AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway	14
miR‑654‑3p suppresses cell viability and promotes apoptosis by targeting RASAL2 in non‑small‑cell lung cancer	14
Role of the SIRT1/p53 regulatory axis in oxidative stress‑mediated granulosa cell apoptosis	14
Expression levels of specific microRNAs are increased after exercise and are associated with cognitive improvement in Parkinson's disease	14
Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA	14
Functional role of miR‑155 in physiological and pathological processes of liver injury (Review)	14
Ghrelin and its role in gastrointestinal tract tumors (Review)	14
Oral peroxidases: From antimicrobial agents to ecological actors (Review)	14
Cardiomyocyte death in sepsis: Mechanisms and regulation (Review)	14
Comparison of single‑nucleus and single‑cell transcriptomes in hepatocellular carcinoma tissue	14
circPTPN22 as a novel biomarker and ceRNA in peripheral blood mononuclear cells of rheumatoid arthritis	14
Astragaloside IV attenuates hypoxia‑induced pulmonary vascular remodeling via the Notch signaling pathway	14
Nicotine promotes chronic obstructive pulmonary disease via inducing pyroptosis activation in bronchial epithelial cells	14
miR‑126 overexpression attenuates oxygen‑glucose deprivation/reperfusion injury by inhibiting oxidative stress and inflammatory response via the activation of SIRT1/Nrf2 signaling pathway in human umb	14
Catalpol inhibits the proliferation, migration and metastasis of HCC cells by regulating miR‑140‑5p expression	13
Nerve growth factor regulates liver cancer cell polarity and motility	13
Lycium barbarum polysaccharides attenuate cardiovascular oxidative stress injury by enhancing the Keap1/Nrf2 signaling pathway in exhaustive exercise rats	13
Dihydromyricetin inhibits oxidative stress and apoptosis in oxygen and glucose deprivation/reoxygenation‑induced HT22 cells by activating the Nrf2/HO‑1 pathway	13
Interactions of circRNAs with methylation: An important aspect of circRNA biogenesis and function (Review)	13
Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4	13
Berberine alleviates palmitic acid‑induced podocyte apoptosis by reducing reactive oxygen species‑mediated endoplasmic reticulum stress	13
Involvement of TLR2/4‑MyD88‑NF‑κB signaling pathway in the pathogenesis of intracranial aneurysm	13
Cardioprotective effects of hydrogen sulfide in attenuating myocardial ischemia‑reperfusion injury (Review)	13
Green tea protects against hippocampal neuronal apoptosis in diabetic encephalopathy by inhibiting JNK/MLCK signaling	13
Protective effect of hydrogen sulfide on the kidney (Review)	13
Protective effects of different anti‑inflammatory drugs on tracheal stenosis following injury and potential mechanisms	13
AMPK‑SIRT1 pathway dysfunction contributes to neuron apoptosis and cognitive impairment induced by sevoflurane	13
Salidroside inhibits endothelial‑mesenchymal transition via the KLF4/eNOS signaling pathway	13
CircRNA_0044556 diminishes the sensitivity of triple‑negative breast cancer cells to adriamycin by sponging miR‑145 and regulating NRAS	13
Cycloastragenol alleviates airway inflammation in asthmatic mice by inhibiting autophagy	13
HOXD9‑induced SCNN1A upregulation promotes pancreatic cancer cell proliferation, migration and predicts prognosis by regulating epithelial‑mesenchymal transformation	13
Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324	13
Overexpression of hsa_circ_0001445 reverses oxLDL‑induced inhibition of HUVEC proliferation via SRSF1	13
Ferroptosis‑related long non‑coding RNAs and the roles of LASTR in stomach adenocarcinoma	13
A cerebrospinal fluid microRNA analysis: Progressive supranuclear palsy	13
Porcupine inhibitor LGK‑974 inhibits Wnt/β‑catenin signaling and modifies tumor‑associated macrophages resulting in inhibition of the malignant behaviors of non‑small cell lung cancer cells	13
Liraglutide protects palmitate-induced INS-1 cell injury by enhancing autophagy mediated via FoxO1	13
κ‑opioid receptor agonist U50488H attenuates postoperative cognitive dysfunction of cardiopulmonary bypass rats through the PI3K/AKT/Nrf2/HO‑1 pathway	13
lncRNA GAS5‑mediated miR‑23a‑3p promotes inflammation and cell apoptosis by targeting TLR4 in a cell model of sepsis	13
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway	13
lncRNA TUG1 regulates angiogenesis via the miR‑204‑5p/JAK2/STAT3 axis in hepatoblastoma	12
A novel update on vitamin D in recurrent pregnancy loss (Review)	12
Tryptophan 2, 3‑dioxygenase promotes proliferation, migration and invasion of ovarian cancer cells	12
MicroRNA‑744‑5p is downregulated in colorectal cancer and targets SEPT2 to suppress the malignant phenotype	12
Interaction of non‑parenchymal hepatocytes in the process of hepatic fibrosis (Review)	12
MicroRNA‑149‑3p inhibits cell proliferation by targeting AKT2 in oral squamous cell carcinoma	12
Exosomes in serum‑free cultures of THP‑1 macrophages infected with Mycobacterium tuberculosis	12
Potential intervention target of atherosclerosis: Ferroptosis (Review)	12
Chemokine CCL20 promotes the paclitaxel resistance of CD44⁺CD117⁺ cells via the Notch1 signaling pathway in ovarian cancer	12
Long non‑coding RNA XIST promotes cerebral ischemia/reperfusion injury by modulating miR‑27a‑3p/FOXO3 signaling	12
Regulatory role of the TLR4/JNK signaling pathway in sepsis‑induced myocardial dysfunction	12
OxLDL/β2GPI/anti‑β2GPI Ab complex induces inflammatory activation via the TLR4/NF‑κB pathway in HUVECs	12
Hyperoside protects cardiomyocytes against hypoxia‑induced injury via upregulation of microRNA‑138	12
hsa_circ_0058357 acts as a ceRNA to promote non‑small cell lung cancer progression via the hsa‑miR‑24‑3p/AVL9 axis	12
MYCN‑amplified neuroblastoma cell‑derived exosomal miR‑17‑5p promotes proliferation and migration of non‑MYCN amplified cells	12