OOIR: Observatory of International Research

Papers

(The TQCC of Therapeutic Advances in Musculoskeletal Disease is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
An update on the use of conventional and biological disease-modifying anti-rheumatic drugs in hand osteoarthritis	133
Is there wastage in the research resources for ankylosing spondylitis? An analysis of clinical trial discontinuation and nonpublication outcome	73
The socioeconomic status of patients with ankylosing spondylitis and its association with the burden of the disease and permanent disability: a cross-sectional cluster analysis	41
Actigraphy-derived physical activity levels and circadian rhythm parameters in patients with psoriatic arthritis: relationship with disease activity, mood, age and BMI	39
Big data analyses and individual health profiling in the arena of rheumatic and musculoskeletal diseases (RMDs)	30
Safety and efficacy of SHR4640 combined with febuxostat for primary hyperuricemia: a multicenter, randomized, double-blind, phase II study	30
Anti-sclerostin antibodies: a new frontier in fragility fractures treatment	30
Cardio-rheumatology: integrated care and the opportunities for personalized medicine	28
Comparable long-term retention rates and effects on bone mineral density of denosumab treatment in patients with osteoporosis with or without autoimmune inflammatory rheumatic diseases: real-life data	28
Similarities and differences: disentangling the intersection between axial psoriatic arthritis and axial spondyloarthritis	28
Tocilizumab in visual involvement of giant cell arteritis: a multicenter study of 471 patients	28
Counting the costs: a nationwide study on healthcare use following an adalimumab biosimilar switch in >1300 inflammatory arthritis patients	27
Clinical and immunological study of Tofacitinib and Baricitinib in refractory Blau syndrome: case report and literature review	26
Comparison of remission criteria in patients with rheumatoid arthritis treated with biologic or targeted synthetic disease-modifying anti-rheumatic drugs: results from a nationwide registry	26
Calcineurin inhibitors in systemic sclerosis – a systematic literature review	25
Health disparities in rheumatoid arthritis	23
Plasma calprotectin as a biomarker of ultrasound synovitis in rheumatoid arthritis patients receiving IL-6 antagonists or JAK inhibitors	22
Based on minimal clinically important difference values, a moderate dose of tanezumab may be a better option for treating hip or knee osteoarthritis: a meta-analysis of randomized controlled trials	22
Reduced bone mineral density in patients with idiopathic inflammatory myopathies: a case-control study	22
Wearable transcutaneous electrical nerve stimulation (actiTENS®) is effective and safe for the treatment of knee osteoarthritis pain: a randomized controlled trial versus weak opioids	21
The challenge of pharmacotherapy for musculoskeletal pain: an overview of unmet needs	20
A glimpse into the future of systemic lupus erythematosus	20
Sjögren syndrome: looking forward to the future	19
Estimation of fracture risk by the FRAX tool in patients with systemic lupus erythematosus: a 10-year longitudinal validation study	19
Bone fragility: conceptual framework, therapeutic implications, and COVID-19-related issues	18

Real-world evidence to assess the effectiveness of platelet-rich plasma in the treatment of knee degenerative pathology: a prospective observational study	17
The association between gout flares and monosodium urate burden assessed using musculoskeletal ultrasound in patients with gout	17
Stromal vascular fraction therapy for knee osteoarthritis: a systematic review	17
Future challenges in rheumatology – is telemedicine the solution?	17
Tofacitinib as an alternative therapy for refractory intestinal Behçet’s syndrome	16
Role of imaging for eligibility and safety of a-NGF clinical trials	16
Early knee OA definition–what do we know at this stage? An imaging perspective	16
Intramuscular methylprednisolone administration in hand osteoarthritis patients: a feasibility study to inform a randomized controlled trial	15
Gout increases length of stay in patients hospitalized for heart failure exacerbation	15
Effects of acupuncture versus placebo on clinical status and potential specific effects in Fibromyalgia: an umbrella review of 11 meta-analyses	15
Treatment with adalimumab in patients with chronic inflammatory rheumatic diseases: a study of treatment trajectories on a patient level in routine care	15
T-score discordance between hip and lumbar spine: risk factors and clinical implications	15
Development and evaluation of a multivariable prediction model for clinical improvement in an established cohort of Colombian rheumatoid arthritis patients	14
Systemic lupus erythematosus is associated with increased risk of Parkinson’s disease	14
Delayed treatment with a tumor necrosis factor alpha blocker associated with worse outcomes in patients with spondyloarthritis: data from the Czech National Registry ATTRA	14
Evaluation of local tissue peri-implant reaction in total knee arthroplasty failure cases	14
Bone marrow edema in children: chronic nonbacterial osteomyelitis and its mimickers	13
Mechanisms hypothesized for pain-relieving effects of exercise in fibromyalgia: a scoping review	13
Magnetic resonance imaging assessments for knee segmentation and their use in combination with machine/deep learning as predictors of early osteoarthritis diagnosis and prognosis	13
MRI lesions in SpA: a comparison with noninflammatory back pain using propensity score adjustment method	13
Repurposed and investigational disease-modifying drugs in osteoarthritis (DMOADs)	13
An oleuropein-based dietary supplement may improve joint functional capacity in older people with high knee joint pain: findings from a multicentre-RCT and post hoc analysis	13
Advanced imaging techniques in crystal arthritis	13
A novel infrapatellar approach of ultrasound-guided intra-articular injection of the knee from both lateral and medial side: a case series	13
The analysis of the pulmonary domain involvement in Sjögren’s disease	12
Metabolic syndrome and psoriatic arthritis: the role of weight loss as a disease-modifying therapy	12
Precision medicine using molecular-target drugs in psoriatic arthritis	12
Precision medicine in axial spondyloarthritis: current opportunities and future perspectives	12
Immunogenicity and safety of inactivated and mRNA COVID-19 vaccines in patients with systemic lupus erythematosus	11
SARS-CoV-2 vaccination willingness and predictors in patients with chronic inflammatory rheumatic diseases (CIRD) and without CIRD	11
Risk factors associated with the occurrence of total knee arthroplasty in patients with knee osteoarthritis: a nested case–control study	11
Medication holidays in osteoporosis: evidence-based recommendations from the Italian guidelines on ‘Diagnosis, risk stratification, and continuity of care of fragility fractures’ based on a systematic	11
Circulating microRNAs differentiate fast-progressing from slow-progressing and non-progressing knee osteoarthritis in the Osteoarthritis Initiative cohort	11
A broad look into the future of rheumatoid arthritis	11
Effects of adipose-derived mesenchymal stem cell conditioned medium on human tenocytes exposed to high glucose	11
A glance into the future of myositis therapy	10
Measuring sedentary behavior using waist- and thigh-worn accelerometers and inclinometers – are the results comparable?	10
Muscle health in ankylosing spondylitis: effects of disease duration, inflammation, education level, and spinal mobility on skeletal muscle atrophy	10
Latest insights in disease-modifying osteoarthritis drugs development	10