OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Nephrology is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
A UMOD variant with intermediate effects	723
Mentorship in the lives of scholars	474
Engineered CAR macrophages target kidney inflammation	399
Age-old musings: twenty-first century management of advanced kidney disease in older individuals	382
Making advance care planning easier for adults with kidney disease and their clinicians	339
The GLP-1 receptor agonist revolution comes to nephrology	339
Role of the gut microbiota in the pathogenesis of IgA nephropathy	338
Disaster preparedness for patients with kidney disease	307
Endoplasmic reticulum-mediated organelle crosstalk in kidney disease	256
Uropathogen and host responses in pyelonephritis	247
Designing acute kidney injury clinical trials	223
Kidney health within the broader non-communicable disease agenda	198
Vaccination in patients with kidney failure: lessons from COVID-19	196
Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions	175
Treatment of chronic kidney disease in older populations	172
A single-cell atlas of DKD treatment responses	171
Daprodustat for anaemia in CKD	159
Roles of sensory receptors in non-sensory organs: the kidney and beyond	157
Beyond state borders: transforming dialysis care for undocumented immigrants	154
Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies	151
GWAS scorecard prioritizes kidney genes using coding and regulatory variants	149
Genetic determinants of urine and plasma metabolite levels	149
Consideration of sex differences is necessary to achieve health equity	142
Complosome — the intracellular complement system	139
Phosphate sensing via PTC glycolysis	133

Interferon blockade in lupus: effects on antiviral immunity	132
Mutational signatures of ccRCC vary between geographical regions	131
Bringing Pride to nephrology	130
Reducing preventable acute kidney injury in a hospital setting	128
Clonal haematopoiesis and AKI	126
Reference-trial-informed design to explore treatment effects in trial-underrepresented subgroups	126
The effects of sex hormone therapy on kidney function	122
Informing clinical decision making during a pandemic — a call for better preparedness	120
The roles of hyaluronan in kidney development, physiology and disease	118
Menopause and chronic kidney disease	117
Aquaporin water channels: roles beyond renal water handling	116
Increasing diversity and inclusion in nephrology clinical trials	108
Benefits of actin cytoskeleton stabilization	107
Innovating dialysis through computational modelling of hollow-fibre haemodialysers	105
From mapping kidney function to mechanism and prediction	103
Identification of erythropoietin-producing cells	102
NUAK1 promotes kidney fibrosis	100
Design of a renal-sparing antifungal	94
Tertiary lymphoid organs contribute to kidney allograft rejection	93
Heat and health inequity: acting on determinants of health to promote heat justice	92
Treatment of SLE with anti-CD19 CAR-T cells	84
Pathological mechanisms of kidney disease in ageing	83
International expert consensus statement on the diagnosis and management of congenital nephrogenic diabetes insipidus (arginine vasopressin resistance)	83
Neutrophils and NETs in kidney disease	82
Long-term health outcomes associated with hydration status	78
Salt substitution: opportunities and challenges for nephrology	77
From fat to filter: the effect of adipose tissue-derived signals on kidney function	75
RNA-binding proteins and their role in kidney disease	73
The role of complement in kidney disease	72
The evolving landscape of immune-mediated glomerular diseases	72
Reaping the rewards of mechanistic discovery in glomerular disease	71
Author Correction: Chronic cardiovascular–kidney disorder: a new conceptual framework	69
Network medicine: an approach to complex kidney disease phenotypes	64
An integrated approach towards a public health perspective on chronic kidney disease	64
MSC therapy for diabetic kidney disease and nephrotic syndrome	64
Reducing stress-induced CHOP is renoprotective	63
A pathway of osmotic stress-induced necroptosis	63
Patient-centred approaches for the management of unpleasant symptoms in kidney disease	61
A golden year of innovative kidney disease therapeutics	61
Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges	60
Combination therapy for kidney disease in people with diabetes mellitus	60
Drosophila melanogaster: a simple genetic model of kidney structure, function and disease	59
Consequence of microvascular inflammation in transplantation	58
Ketogenic diet benefits in critically ill patients with sepsis	56
The cilia mechanosensation debate gets (bio)physical	53
CKD-specific ASCVD risk prediction tools	53
Transcatheter mitral valve repair in patients with CKD	51
Educating primary healthcare providers about kidney disease	51
Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors	51
GalNAc-T14-associated defects in B cell homing in IgA nephropathy	50

Consequences of famine and malnourishment on kidney health	49
Continuing kidney care in conflicts	47
Kidney complications of parasitic diseases	47
Role of the cGAS–STING pathway in systemic and organ-specific diseases	46
Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney	46
Dietary protection of proximal tubules in diabetes	45
Mechanism of B cell survival in lupus nephritis	45
Gene therapy in a model of nephrotic syndrome	45
Stem cell–kidney transplantation in Schimke immuno-osseous dysplasia	43
Targeting IL-1Ra to attenuate fungal infection	42
Nephrology education and training in Africa	41
Steps forward in the treatment of IgA nephropathy	40
Mannose as a driver of γδ T cell kidney infiltration	40
Multifaceted innovations needed to advance transplant nephrology	40
The kidney is a novel target of metformin	38
IL-6 signalling contributes to the pathogenesis of uraemic calciphylaxis	38
Born too soon: lifelong kidney risks and the importance of early intervention	38
Metabolic alterations in hereditary and sporadic renal cell carcinoma	36
Clinical practice recommendations for primary hyperoxaluria: an expert consensus statement from ERKNet and OxalEurope	35
Role of necroptosis in kidney health and disease	35
Chronic cardiovascular–kidney disorder: a new conceptual framework	35
Epithelial cell states associated with kidney and allograft injury	35
A guide to gene–disease relationships in nephrology	34
Cardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome	34
ALCAM–CD6 in lupus nephritis	32
Fasting induces structural and functional changes in the peritoneal membrane	32
A multidisciplinary approach to cardiorespiratory fitness in CKD	32
Derivation of collecting duct organoids	31
Author Correction: Therapeutic advances in COVID-19	31
Insights into the impact of pregnancy on kidney disease	31
Author Correction: Regulatory T cells in autoimmune kidney diseases and transplantation	29
Strategies to achieve gender equity in nephrology	29
The increasing burden of mild and moderate anaemia in CKD	28
Tissue-resident memory T cells in the urogenital tract	28
Fibroblast activation and heterogeneity in fibrotic disease	27
From big data to smart decisions: artificial intelligence in kidney risk assessment	27
Exercise and chronic kidney disease: potential mechanisms underlying the physiological benefits	27
Leveraging data as a patient–scientist: frustrations and opportunities	27
The impact of intrauterine growth restriction and prematurity on nephron endowment	27
Renal nerves in physiology, pathophysiology and interoception	27
The perils of misinformation: when health literacy goes awry	26
Acute kidney injury in patients with burns	26
Switching off SOX9 for epithelial recovery after AKI	26
Digital determinants of health: opportunities and risks amidst health inequities	25
Experimental evidence for a pathogenic role of anti-PLA2R1 antibodies in membranous nephropathy	25
CD38 — a new target in renal immune disease	24
Crosstalk between glomeruli and tubules	24
Collagen formation, function and role in kidney disease	22
Impact of persistent conflict and destabilizing events on dialysis care	22
Functional consequences of spatial, temporal and ligand bias of G protein-coupled receptors	22
Hope for resistant hypertension through BrigHTN and PRECISION	20
The genetics of kidney stone disease and nephrocalcinosis	19
Nephrology and women’s health post-Roe v. Wade: we must do better	19
Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup	19
Chlorthalidone in advanced CKD	19
The impact of population ageing on the burden of chronic kidney disease	19