OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Nephrology is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
A UMOD variant with intermediate effects	813
Making advance care planning easier for adults with kidney disease and their clinicians	666
Mentorship in the lives of scholars	464
Engineered CAR macrophages target kidney inflammation	459
Role of the gut microbiota in the pathogenesis of IgA nephropathy	416
Inhibitory effects of oestradiol on ferroptosis may underlie sex differences in AKI	394
The changing landscape of kidney health and disease in Africa	390
Endoplasmic reticulum-mediated organelle crosstalk in kidney disease	350
The GLP-1 receptor agonist revolution comes to nephrology	300
Disaster preparedness for patients with kidney disease	289
Vaccination in patients with kidney failure: lessons from COVID-19	276
Designing acute kidney injury clinical trials	224
Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions	223
Urine as a source of biomarkers and biological knowledge in chronic kidney disease	217
Uropathogen and host responses in pyelonephritis	204
Treatment of chronic kidney disease in older populations	198
Kidney health within the broader non-communicable disease agenda	184
A single-cell atlas of DKD treatment responses	180
Genetic determinants of urine and plasma metabolite levels	170
GWAS scorecard prioritizes kidney genes using coding and regulatory variants	168
Beyond state borders: transforming dialysis care for undocumented immigrants	166
Strategic rebalancing of kidney-related investments is key to implementing the WHO kidney health resolution	166
Roles of sensory receptors in non-sensory organs: the kidney and beyond	165
Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies	153
Consideration of sex differences is necessary to achieve health equity	152

Complosome — the intracellular complement system	147
Phosphate sensing via PTC glycolysis	146
Increasing diversity and inclusion in nephrology clinical trials	144
Mutational signatures of ccRCC vary between geographical regions	143
Bringing Pride to nephrology	139
20 years of Nature Reviews Nephrology	137
Informing clinical decision making during a pandemic — a call for better preparedness	129
Reference-trial-informed design to explore treatment effects in trial-underrepresented subgroups	129
Reducing preventable acute kidney injury in a hospital setting	129
The effects of sex hormone therapy on kidney function	122
Clonal haematopoiesis and AKI	113
Interferon blockade in lupus: effects on antiviral immunity	110
Menopause and chronic kidney disease	105
The roles of hyaluronan in kidney development, physiology and disease	102
Aquaporin water channels: roles beyond renal water handling	102
Identification of erythropoietin-producing cells	92
Design of a renal-sparing antifungal	89
NUAK1 promotes kidney fibrosis	87
Benefits of actin cytoskeleton stabilization	86
Treatment of SLE with anti-CD19 CAR-T cells	86
Heat and health inequity: acting on determinants of health to promote heat justice	83
Salt substitution: opportunities and challenges for nephrology	82
Long-term health outcomes associated with hydration status	81
Innovating dialysis through computational modelling of hollow-fibre haemodialysers	79
International expert consensus statement on the diagnosis and management of congenital nephrogenic diabetes insipidus (arginine vasopressin resistance)	74
Guidelines for the use of economic evaluation to inform policies around access to treatment for kidney failure	74
Tertiary lymphoid organs contribute to kidney allograft rejection	72
From fat to filter: the effect of adipose tissue-derived signals on kidney function	71
Neutrophils and NETs in kidney disease	69
The role of complement in kidney disease	69
Reaping the rewards of mechanistic discovery in glomerular disease	68
Pathological mechanisms of kidney disease in ageing	68
Author Correction: Chronic cardiovascular–kidney disorder: a new conceptual framework	67
A label-free optical analysis for molecular nephrology	66
The evolving landscape of immune-mediated glomerular diseases	66
A pathway of osmotic stress-induced necroptosis	65
A golden year of innovative kidney disease therapeutics	65
Network medicine: an approach to complex kidney disease phenotypes	64
Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges	61
MSC therapy for diabetic kidney disease and nephrotic syndrome	61
An integrated approach towards a public health perspective on chronic kidney disease	61
Drosophila melanogaster: a simple genetic model of kidney structure, function and disease	61
Consequence of microvascular inflammation in transplantation	59
Patient-centred approaches for the management of unpleasant symptoms in kidney disease	59
Combination therapy for kidney disease in people with diabetes mellitus	59
CKD-specific ASCVD risk prediction tools	57
Ketogenic diet benefits in critically ill patients with sepsis	56
The cilia mechanosensation debate gets (bio)physical	55
Transcatheter mitral valve repair in patients with CKD	54
PDGFRβ CAR T cells improve fibrosis in kidney disease models	54

GalNAc-T14-associated defects in B cell homing in IgA nephropathy	54
Consequences of famine and malnourishment on kidney health	53
Kidney complications of parasitic diseases	53
Educating primary healthcare providers about kidney disease	53
Continuing kidney care in conflicts	52
Long COVID and the kidney	50
Role of the cGAS–STING pathway in systemic and organ-specific diseases	50
Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors	50
Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney	49
Stem cell–kidney transplantation in Schimke immuno-osseous dysplasia	46
Mechanism of B cell survival in lupus nephritis	45
Dietary protection of proximal tubules in diabetes	45
Gene therapy in a model of nephrotic syndrome	42
Multifaceted innovations needed to advance transplant nephrology	41
Mannose as a driver of γδ T cell kidney infiltration	40
The kidney is a novel target of metformin	37
IL-6 signalling contributes to the pathogenesis of uraemic calciphylaxis	37
Steps forward in the treatment of IgA nephropathy	37
Born too soon: lifelong kidney risks and the importance of early intervention	36
Epithelial cell states associated with kidney and allograft injury	36
The genetics of hypertension	35
A guide to gene–disease relationships in nephrology	35
Chronic cardiovascular–kidney disorder: a new conceptual framework	35
Generation of self-assembling kidney progenitor assembloids	35
Targeting IL-1Ra to attenuate fungal infection	34
Cardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome	33
Clinical practice recommendations for primary hyperoxaluria: an expert consensus statement from ERKNet and OxalEurope	31
Role of necroptosis in kidney health and disease	30
A multidisciplinary approach to cardiorespiratory fitness in CKD	30
Fasting induces structural and functional changes in the peritoneal membrane	30
Metabolic alterations in hereditary and sporadic renal cell carcinoma	30
Derivation of collecting duct organoids	30
Author Correction: Regulatory T cells in autoimmune kidney diseases and transplantation	29
A guide to uraemic toxicity	29
Author Correction: Therapeutic advances in COVID-19	29
Leveraging data as a patient–scientist: frustrations and opportunities	29
ALCAM–CD6 in lupus nephritis	29
Strategies to achieve gender equity in nephrology	29
Green nephrology: from evidence to action	27
The increasing burden of mild and moderate anaemia in CKD	27
From big data to smart decisions: artificial intelligence in kidney risk assessment	25
The immunology of sepsis: translating new insights into clinical practice	25
Tissue-resident memory T cells in the urogenital tract	25
The perils of misinformation: when health literacy goes awry	23
Fibroblast activation and heterogeneity in fibrotic disease	23
Renal nerves in physiology, pathophysiology and interoception	21
Exercise and chronic kidney disease: potential mechanisms underlying the physiological benefits	21
Insights into the impact of pregnancy on kidney disease	21
Switching off SOX9 for epithelial recovery after AKI	21
The impact of intrauterine growth restriction and prematurity on nephron endowment	21
Acute kidney injury in patients with burns	21
Impact of persistent conflict and destabilizing events on dialysis care	20
CD38 — a new target in renal immune disease	20
Experimental evidence for a pathogenic role of anti-PLA2R1 antibodies in membranous nephropathy	20
Hope for resistant hypertension through BrigHTN and PRECISION	19
Digital determinants of health: opportunities and risks amidst health inequities	19