Nature Reviews Cardiology

Papers
(The TQCC of Nature Reviews Cardiology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
The future of cardiac xenotransplantation726
Congenital heart disease and risk of severe COVID485
PPARα regulates the development and inflammation of vein graft lesions483
GRK5 linked to cardiac dysfunction and leukocyte recruitment after MI450
Social disparities in COVID-19 prevention446
FFR-guided PCI vs CABG surgery in multivessel CAD436
Electronic alerts can PROMPT guideline-directed care for HFrEF425
α-Myosin-specific CD8+ T cells drive ICI-related myocarditis396
Non-fatal MI as surrogate end point for all-cause or cardiovascular mortality356
Physicians in the era of technology-enabled diagnostics342
Smartwatch detection of left ventricular dysfunction294
Immediate non-inferior to staged complete revascularization277
Intravascular imaging improves outcomes264
Hidden disparities in the rising prevalence of bystander cardiopulmonary resuscitation232
Cost-effective benefit of iron-replacement therapy217
Sacubitril–valsartan shows benefit in heart failure with ejection fraction of >40%216
Antibody treatment to deplete transthyretin amyloid deposits in the heart200
Targeting ALK1 to block LDL transcytosis and halt atherosclerosis198
Pacing with respiratory sinus arrhythmia improves outcomes in heart failure188
Targeting the adipose tissue to protect the heart180
Truncated titin proteins in the pathophysiology of DCM176
Basophils promote healing after MI162
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications159
Injectable and conductive cardiac patch155
Self-monitoring strategy reduces postpartum hypertension and cardiac remodelling145
Base editing therapy corrects long QT syndrome in mice142
PCI for stable angina141
Pulsed-field ablation: a revolution in atrial fibrillation therapy140
Revealing the structure of the cardiac myosin filament140
Mentorship in cardiology: building the mentoring relationship138
Functional testing after PCI in high-risk patients130
Oxygen and BP targets for OHCA127
Hypertension in China: epidemiology and treatment initiatives118
Benefit of vutrisiran in transthyretin amyloidosis with cardiomyopathy118
Clonal haematopoiesis: an emerging causal risk factor for atherosclerotic CVD117
RNA-based therapies targeting APOC3 lower triglyceride levels in patients with hypertriglyceridaemia116
Aggregation of big tau disrupts microtubules and causes diastolic dysfunction116
Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy114
No benefit of β-blockers after myocardial infarction with preserved ejection fraction114
LIPC variant in combined hypocholesterolaemia108
No benefit of colchicine to prevent AF or myocardial injury after non-cardiac surgery107
Guidelines to lower intake of added sugar are necessary and justified107
CAS and CEA have similar risks and benefits105
Limited benefit of triglyceride lowering with fibrates in statin-treated patients99
Bariatric metabolic surgery more effective than GLP1R agonists in preventing congestive HF98
Carotid stenosis management: time to address the misconceptions (‘furphies’)92
Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases89
Iron deficiency and supplementation in heart failure89
Applications of artificial intelligence in cardiovascular imaging87
Accelerated reduction in global cardiovascular disease is essential to achieve the Sustainable Development Goals84
Screening for Helicobacter pylori infection in patients with cardiovascular and gastrointestinal disease84
Three different therapies to target PCSK984
Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention?82
The role of cardiac pericytes in health and disease: therapeutic targets for myocardial infarction81
Genetics and mechanisms of thoracic aortic disease81
Macrophages in cardiac remodelling after myocardial infarction81
The spleen in ischaemic heart disease79
Blood pressure and its variability: classic and novel measurement techniques79
Haematometabolism rewiring in atherosclerotic cardiovascular disease75
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?74
Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective74
Changing epidemiology of congenital heart disease: effect on outcomes and quality of care in adults72
Electroimmunology and cardiac arrhythmia72
Inclusion of remnant cholesterol improves risk prediction for ischaemic heart disease72
Neuroimmune axis of cardiovascular control: mechanisms and therapeutic implications71
The use of new CRISPR tools in cardiovascular research and medicine69
Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development65
Sex-related similarities and differences in responses to heart failure therapies60
Restoration of flow in the aorta: a novel therapeutic target in aortic valve intervention59
Empagliflozin improves clinical outcomes for HFpEF in EMPEROR-Preserved58
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential57
Social determinants of atrial fibrillation56
Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease54
Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention53
2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease52
A roadmap of strategies to support cardiovascular researchers: from policy to practice51
Sit less and move more for cardiovascular health: emerging insights and opportunities51
Publisher Correction: Cardiac involvement in the long-term implications of COVID-1951
IRONMAN adds support for iron repletion in HF50
Vascular endothelial cell development and diversity50
Strategies to prevent burnout in the cardiovascular health-care workforce49
Universal flu vaccines: a shot at lifelong cardioprotection?48
Current and future applications of virtual reality technology for cardiac interventions48
Travelling with heart failure: risk assessment and practical recommendations48
A fresh look at coronary microembolization48
Cardiac optogenetics: controlling the heart with light47
The need for increased pragmatism in cardiovascular clinical trials47
Defining iron deficiency in patients with heart failure46
Factor XI inhibitors in patients with cardiovascular disease and a high risk of bleeding: a cautionary tale46
AI outperforms sonographers at diagnosing cardiac function on echocardiography45
Self-expanding valves more beneficial than balloon-expandable valves in patients with a small aortic annulus45
Heterogeneity of the post-infarct epicardium43
Anti-IL-1β therapy lowers leukocyte supply and uptake in atherosclerosis42
Abbreviating DAPT reduces the risk of bleeding42
Macrophage OLFR2 activation is atherogenic42
Sirtuin 2 protects against cardiac ageing39
Mending broken hearts with the help of epigenetic remodellers39
Resurgence of renal denervation for resistant hypertension38
Blocking endothelial lipase raises HDL-C levels38
CD200 is an atheroprotective immune checkpoint38
Vitamin K antagonists for RHD-associated AF37
Polypills for the secondary prevention of MACE36
Cardiovascular benefits of statins outweigh small risk of muscle pain33
A proteomic model shows potential as a surrogate end point for CVD risk32
Diversity in human genetics studies accelerates discovery and improves health care31
Glucocorticoid receptor inhibition promotes cardiac repair after MI31
Promising findings for cell therapy in HFrEF30
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials29
Boosting mitochondrial metabolism with dietary supplements in heart failure29
Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures28
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease28
Consequences of ionizing radiation exposure to the cardiovascular system28
Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium27
PPAR control of metabolism and cardiovascular functions27
Immune and inflammatory mechanisms in hypertension26
Metabolic mechanisms in physiological and pathological cardiac hypertrophy: new paradigms and challenges24
Non-canonical WNT signalling in cardiovascular disease: mechanisms and therapeutic implications24
Immune cell profiling in atherosclerosis: role in research and precision medicine24
Alternative defibrillation strategies improve outcomes23
Contemporary coronary artery bypass graft surgery and subsequent percutaneous revascularization23
An all-virtual clinical trial to assess a heart failure drug23
Flow-induced reprogramming of endothelial cells in atherosclerosis23
Gout flares can precede cardiovascular events22
Gut-derived low-grade endotoxaemia, atherothrombosis and cardiovascular disease22
Ablation plus pacing strategy reduces mortality in patients with AF and HF20
Levothyroxine supplementation does not improve heart transplantation from brain-dead donors20
Targeted therapies for cardiac diseases20
New insights into OCT-guided PCI19
The cardiac parasympathetic system has two parallel circuits19
Age-induced senescence impairs the neurovascular interface in the heart19
Explaining how a cardiac reflex causes syncope19
Complete revascularization in MI: role in older patients and optimal timing19
Electron microscopy of cardiac 3D nanodynamics: form, function, future18
Innate lymphoid cells improve recovery of cardiac function after MI18
Left atrial appendage occlusion18
Inhibiting aldosterone synthase reduces blood pressure17
Selective JAG1–NOTCH3 targeting shows potential for treating PAH16
Cryoballoon ablation reduces AF progression16
MicroRNA directly modulates cardiac ion channel16
Artificially transplanted mitochondria in endothelial cells promote mitophagy15
Obstructive sleep apnoea heterogeneity and cardiovascular disease14
Cardiac fibroblasts and mechanosensation in heart development, health and disease14
Epidemiology of cardiovascular disease in Europe13
Update on the pathophysiology and medical treatment of peripheral artery disease13
Pathophysiology and risk factors of peripartum cardiomyopathy12
Ultra-processed foods and cardiovascular disease12
Bioengineering approaches to treat the failing heart: from cell biology to 3D printing12
The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases12
Hallmarks of cardiovascular ageing11
Cardiovascular physiology and pathophysiology at high altitude11
The rapid delayed-rectifier potassium current: a biophysical basis for cardiac repolarization and arrhythmia10
The role of aldehyde dehydrogenase 2 in cardiovascular disease10
Effective CRISPR modulation of complex non-coding RNA loci10
Modulating the gut microbiota with dietary interventions to protect against cardiometabolic disease10
Pathophysiological insights into HFpEF from studies of human cardiac tissue10
A newly identified gut hormone suppresses cholesterol production in the liver10
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