Nature Reviews Cardiology

Article	Citations
The future of cardiac xenotransplantation	726
Congenital heart disease and risk of severe COVID	485
PPARα regulates the development and inflammation of vein graft lesions	483
GRK5 linked to cardiac dysfunction and leukocyte recruitment after MI	450
Social disparities in COVID-19 prevention	446
FFR-guided PCI vs CABG surgery in multivessel CAD	436
Electronic alerts can PROMPT guideline-directed care for HFrEF	425
α-Myosin-specific CD8+ T cells drive ICI-related myocarditis	396
Non-fatal MI as surrogate end point for all-cause or cardiovascular mortality	356
Physicians in the era of technology-enabled diagnostics	342
Smartwatch detection of left ventricular dysfunction	294
Immediate non-inferior to staged complete revascularization	277
Intravascular imaging improves outcomes	264
Hidden disparities in the rising prevalence of bystander cardiopulmonary resuscitation	232
Cost-effective benefit of iron-replacement therapy	217
Sacubitril–valsartan shows benefit in heart failure with ejection fraction of >40%	216
Antibody treatment to deplete transthyretin amyloid deposits in the heart	200
Targeting ALK1 to block LDL transcytosis and halt atherosclerosis	198
Pacing with respiratory sinus arrhythmia improves outcomes in heart failure	188
Targeting the adipose tissue to protect the heart	180
Truncated titin proteins in the pathophysiology of DCM	176
Basophils promote healing after MI	162
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications	159
Injectable and conductive cardiac patch	155
Self-monitoring strategy reduces postpartum hypertension and cardiac remodelling	145

Base editing therapy corrects long QT syndrome in mice	142
PCI for stable angina	141
Pulsed-field ablation: a revolution in atrial fibrillation therapy	140
Revealing the structure of the cardiac myosin filament	140
Mentorship in cardiology: building the mentoring relationship	138
Functional testing after PCI in high-risk patients	130
Oxygen and BP targets for OHCA	127
Benefit of vutrisiran in transthyretin amyloidosis with cardiomyopathy	118
Hypertension in China: epidemiology and treatment initiatives	118
Clonal haematopoiesis: an emerging causal risk factor for atherosclerotic CVD	117
Aggregation of big tau disrupts microtubules and causes diastolic dysfunction	116
RNA-based therapies targeting APOC3 lower triglyceride levels in patients with hypertriglyceridaemia	116
Benefits of ninerafaxstat in non-obstructive hypertrophic cardiomyopathy	114
No benefit of β-blockers after myocardial infarction with preserved ejection fraction	114
LIPC variant in combined hypocholesterolaemia	108
No benefit of colchicine to prevent AF or myocardial injury after non-cardiac surgery	107
Guidelines to lower intake of added sugar are necessary and justified	107
CAS and CEA have similar risks and benefits	105
Limited benefit of triglyceride lowering with fibrates in statin-treated patients	99
Bariatric metabolic surgery more effective than GLP1R agonists in preventing congestive HF	98
Carotid stenosis management: time to address the misconceptions (‘furphies’)	92
Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases	89
Iron deficiency and supplementation in heart failure	89
Applications of artificial intelligence in cardiovascular imaging	87
Screening for Helicobacter pylori infection in patients with cardiovascular and gastrointestinal disease	84
Three different therapies to target PCSK9	84
Accelerated reduction in global cardiovascular disease is essential to achieve the Sustainable Development Goals	84
Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention?	82
Macrophages in cardiac remodelling after myocardial infarction	81
The role of cardiac pericytes in health and disease: therapeutic targets for myocardial infarction	81
Genetics and mechanisms of thoracic aortic disease	81
The spleen in ischaemic heart disease	79
Blood pressure and its variability: classic and novel measurement techniques	79
Haematometabolism rewiring in atherosclerotic cardiovascular disease	75
Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?	74
Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective	74
Inclusion of remnant cholesterol improves risk prediction for ischaemic heart disease	72
Changing epidemiology of congenital heart disease: effect on outcomes and quality of care in adults	72
Electroimmunology and cardiac arrhythmia	72
Neuroimmune axis of cardiovascular control: mechanisms and therapeutic implications	71
The use of new CRISPR tools in cardiovascular research and medicine	69
Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development	65
Sex-related similarities and differences in responses to heart failure therapies	60
Restoration of flow in the aorta: a novel therapeutic target in aortic valve intervention	59
Empagliflozin improves clinical outcomes for HFpEF in EMPEROR-Preserved	58
Regression of cardiac hypertrophy in health and disease: mechanisms and therapeutic potential	57
Social determinants of atrial fibrillation	56
Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease	54
Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention	53
2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease	52

Sit less and move more for cardiovascular health: emerging insights and opportunities	51
Publisher Correction: Cardiac involvement in the long-term implications of COVID-19	51
A roadmap of strategies to support cardiovascular researchers: from policy to practice	51
IRONMAN adds support for iron repletion in HF	50
Vascular endothelial cell development and diversity	50
Strategies to prevent burnout in the cardiovascular health-care workforce	49
Current and future applications of virtual reality technology for cardiac interventions	48
Travelling with heart failure: risk assessment and practical recommendations	48
A fresh look at coronary microembolization	48
Universal flu vaccines: a shot at lifelong cardioprotection?	48
Cardiac optogenetics: controlling the heart with light	47
The need for increased pragmatism in cardiovascular clinical trials	47
Defining iron deficiency in patients with heart failure	46
Factor XI inhibitors in patients with cardiovascular disease and a high risk of bleeding: a cautionary tale	46
Self-expanding valves more beneficial than balloon-expandable valves in patients with a small aortic annulus	45
AI outperforms sonographers at diagnosing cardiac function on echocardiography	45
Heterogeneity of the post-infarct epicardium	43
Macrophage OLFR2 activation is atherogenic	42
Anti-IL-1β therapy lowers leukocyte supply and uptake in atherosclerosis	42
Abbreviating DAPT reduces the risk of bleeding	42
Mending broken hearts with the help of epigenetic remodellers	39
Sirtuin 2 protects against cardiac ageing	39
CD200 is an atheroprotective immune checkpoint	38
Resurgence of renal denervation for resistant hypertension	38
Blocking endothelial lipase raises HDL-C levels	38
Vitamin K antagonists for RHD-associated AF	37
Polypills for the secondary prevention of MACE	36
Cardiovascular benefits of statins outweigh small risk of muscle pain	33
A proteomic model shows potential as a surrogate end point for CVD risk	32
Glucocorticoid receptor inhibition promotes cardiac repair after MI	31
Diversity in human genetics studies accelerates discovery and improves health care	31
Promising findings for cell therapy in HFrEF	30
Boosting mitochondrial metabolism with dietary supplements in heart failure	29
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials	29
Consequences of ionizing radiation exposure to the cardiovascular system	28
Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures	28
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease	28
PPAR control of metabolism and cardiovascular functions	27
Current and novel biomarkers of thrombotic risk in COVID-19: a Consensus Statement from the International COVID-19 Thrombosis Biomarkers Colloquium	27
Immune and inflammatory mechanisms in hypertension	26
Non-canonical WNT signalling in cardiovascular disease: mechanisms and therapeutic implications	24
Immune cell profiling in atherosclerosis: role in research and precision medicine	24
Metabolic mechanisms in physiological and pathological cardiac hypertrophy: new paradigms and challenges	24
An all-virtual clinical trial to assess a heart failure drug	23
Flow-induced reprogramming of endothelial cells in atherosclerosis	23
Alternative defibrillation strategies improve outcomes	23
Contemporary coronary artery bypass graft surgery and subsequent percutaneous revascularization	23
Gut-derived low-grade endotoxaemia, atherothrombosis and cardiovascular disease	22
Gout flares can precede cardiovascular events	22
Targeted therapies for cardiac diseases	20
Ablation plus pacing strategy reduces mortality in patients with AF and HF	20
Levothyroxine supplementation does not improve heart transplantation from brain-dead donors	20
Explaining how a cardiac reflex causes syncope	19
Complete revascularization in MI: role in older patients and optimal timing	19
New insights into OCT-guided PCI	19
The cardiac parasympathetic system has two parallel circuits	19
Age-induced senescence impairs the neurovascular interface in the heart	19
Left atrial appendage occlusion	18
Electron microscopy of cardiac 3D nanodynamics: form, function, future	18
Innate lymphoid cells improve recovery of cardiac function after MI	18
Inhibiting aldosterone synthase reduces blood pressure	17
MicroRNA directly modulates cardiac ion channel	16
Selective JAG1–NOTCH3 targeting shows potential for treating PAH	16
Cryoballoon ablation reduces AF progression	16
Artificially transplanted mitochondria in endothelial cells promote mitophagy	15
Cardiac fibroblasts and mechanosensation in heart development, health and disease	14
Obstructive sleep apnoea heterogeneity and cardiovascular disease	14
Update on the pathophysiology and medical treatment of peripheral artery disease	13
Epidemiology of cardiovascular disease in Europe	13
Bioengineering approaches to treat the failing heart: from cell biology to 3D printing	12
The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases	12
Pathophysiology and risk factors of peripartum cardiomyopathy	12
Ultra-processed foods and cardiovascular disease	12
Hallmarks of cardiovascular ageing	11
Cardiovascular physiology and pathophysiology at high altitude	11
Modulating the gut microbiota with dietary interventions to protect against cardiometabolic disease	10
Pathophysiological insights into HFpEF from studies of human cardiac tissue	10
A newly identified gut hormone suppresses cholesterol production in the liver	10
The rapid delayed-rectifier potassium current: a biophysical basis for cardiac repolarization and arrhythmia	10
The role of aldehyde dehydrogenase 2 in cardiovascular disease	10

Effective CRISPR modulation of complex non-coding RNA loci	10
Black In Cardio: promoting diversity and representation in the cardiovascular field	9
Uncertainties about left ventricular thrombus after STEMI	9
DYRK1A gene linked to heart defects in Down syndrome	9
Weight loss from surgery or drug therapy reduces blood pressure	9
Cardiac memory: a phenomenon with important clinical implications	8
A phoenix rises from the ashes of cardiac cell therapy	8
Maternal cardiovascular disorders before and during pregnancy and offspring cardiovascular risk across the life course	8
Phase separation of protein kinase A: a new paradigm in cardiac regulation?	8
Tackling inflammation in atherosclerosis	8
Reply to ‘Screening for Helicobacter pylori infection in patients with cardiovascular and gastrointestinal disease’	8
Anticoagulation in patients with atrial high-rate episodes	7
Haemostatic functions of novel synthetic platelets	7
Prehabilitation: evolving role in contemporary cardiac surgery	7
Role of sex hormones in cardiovascular diseases	7
The bidirectional association between atrial fibrillation and myocardial infarction	7
Cardio-onco-metabolism: metabolic remodelling in cardiovascular disease and cancer	7
Roadmap on the use of artificial intelligence for imaging of vulnerable atherosclerotic plaque in coronary arteries	7
Detection of subclinical hypertrophic cardiomyopathy	7
Sodium and potassium intake for CV health	7
β-blockers after MI: does ABYSS confirm REDUCEd use after all?	6
Cardiovascular autonomic dysfunction in post-COVID-19 syndrome: a major health-care burden	6
Dietary patterns to promote cardiometabolic health	6
Smart wearable devices in cardiovascular care: where we are and how to move forward	6
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing	6
Gender medicine: effects of sex and gender on cardiovascular disease manifestation and outcomes	5
Clonal haematopoiesis and atherosclerosis: a chicken or egg question?	5
Autoimmune diseases and atherosclerotic cardiovascular disease	5
AI-driven evolution of precision population cardiovascular health in cities	5
Novel lipid-lowering therapies targeting ANGPTL3 and Lp(a)	5
Long COVID and cardiovascular disease: a learning health system approach	5
Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging: a Consensus Statement from the Quantitative Cardiovascular Imaging Study Group	5
Author Correction: Myocarditis after COVID-19 mRNA vaccination: clinical observations and potential mechanisms	5
RAPID return to sinus rhythm after SVT using intranasal etripamil	5
Atheroimmunology: keeping the immune system in atherosclerosis in check	5
Piezo1 senses pressure overload and initiates cardiac hypertrophy	5
Combined measure of inflammation, cholesterol and lipoprotein(a) predicts 30-year cardiovascular risk in women	5
ASGR1 inhibition stimulates cholesterol excretion	5
Depolarization of fibroblasts in scar tissue drives cardiac excitation	5
Select hPSC-CMs clonally expand in vivo	4
Heart disease causes sleep disturbances via neuroimmune mechanisms	4
A fatty acid from mother’s milk drives cardiomyocyte maturation in newborn mice	4
Sex-chromosome mechanisms contribute to cardiac sex disparities	4
Cardiac fibroblasts contribute to sexually dimorphic responses to cardiac injury	4
Transcatheter repair for severe tricuspid regurgitation	4
Non-thermal ablation of AF is safe and effective	4
Evolving concepts of the vulnerable atherosclerotic plaque and the vulnerable patient: implications for patient care and future research	4
Young women with AMI have worse outcomes than men up to 1 year after discharge	4
Genome editing prevents hypertrophic cardiomyopathy in mice	4
Defining the SAN fibrotic content in failing hearts	4
A tailored cardiac rehabilitation for patients with acute heart failure	4
Adverse professional life experiences may affect mental health among cardiologists	4
Safety of paclitaxel-coated devices in peripheral artery disease	4
Catheter ablation improves outcomes in patients with AF and end-stage HF	4
Restoration of NAD+ levels as a therapy for HFpEF	4
Benefit of early aortic valve surgery in asymptomatic, severe AS	3
Gut bacterium protects against atherosclerosis by degrading BCAAs	3
A distinct platelet differentiation pathway is involved in age-related thrombocytosis	3
Hormone therapy ameliorates ICI-related myocarditis in mice	3
Microbial metabolites reduce SBP in patients with resistant hypertension	3
Early inhibition of IL-6 signalling after an acute MI improves myocardial salvage	3
Non-invasive ultrasound therapy for calcified aortic valve stenosis	3
A machine-learning-derived, in silico marker for CAD identifies underdiagnosed patients	3
Statins outperform dietary supplements for LDL-C lowering	3
Hyperglycaemia-induced trained immunity promotes atherosclerosis	3
Imaging cAMP nanodomains in human iPSC-derived cardiomyocytes	3
CVD screening trial in older men misses primary end point but suggests benefits	3
Identifying leukocyte phenotypes by scRNA-seq to predict cardiovascular risk	3
Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects	3
Reply to: ‘Guidelines on ‘added’ sugars are unscientific and unnecessary’	3
Childhood cardiovascular risk factors lead to heart disease in adults	3
No benefit of routine steroids in infant heart surgery	3
Surgery safer than endovascular therapy for CLTI	3
The roles of female cardiologists in contemporary China	3
Uncovering atherosclerotic cardiovascular disease by PET imaging	3
Increased degradation of desmosomal proteins in ACM	3
Bleeding avoidance strategies in percutaneous coronary intervention	3
CSDE1 regulates LDL receptor levels	3
A cardioimmunologist’s toolkit: genetic tools to dissect immune cells in cardiac disease	2
Our revered and mysterious heart	2
The oral microbiome in the pathophysiology of cardiovascular disease	2
Characterization of the F8 gene: a silver lining in a dark cloud	2
Programmed death of macrophages in atherosclerosis: mechanisms and therapeutic targets	2
Exosome-eluting stents improve vascular remodelling	2
Animal models to study cardiac regeneration	2
Minority stress, discrimination and cardiovascular health	2
Small extracellular vesicles from the infarcted heart can promote tumour growth	2
Immunomodulation and immunopharmacology in heart failure	2
Targeting immune cell recruitment in atherosclerosis	2
Valvular heart disease and cardiomyopathy: reappraisal of their interplay	2
Functional control of myosin motors in the cardiac cycle	2
Author Correction: 2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease	2
OpenEP and EP Workbench for electrophysiology data analysis	2
Clonal haematopoiesis and atherosclerotic cardiovascular disease	2
20 years of Nature Reviews Cardiology	2