OOIR: Observatory of International Research

Papers

(The H4-Index of Alzheimers Research & Therapy is 43. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Genome-wide association study and polygenic risk scores of retinal thickness across the cognitive continuum: data from the NORFACE cohort	483
Granulovacuolar degeneration bodies are independently induced by tau and α-synuclein pathology	158
Comparing a pre-defined versus deep learning approach for extracting brain atrophy patterns to predict cognitive decline due to Alzheimer’s disease in patients with mild cognitive symptoms	158
Retraction Note: Increased Aβ42-α7-like nicotinic acetylcholine receptor complex level in lymphocytes is associated with apolipoprotein E4-driven Alzheimer’s disease pathogenesis	137
A metagenomic study of gut viral markers in amyloid-positive Alzheimer’s disease patients	128
Profiles of subgingival microbiomes and gingival crevicular metabolic signatures in patients with amnestic mild cognitive impairment and Alzheimer’s disease	115
Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data	111
Relationship between hearing impairment and dementia and cognitive function: a Mendelian randomization study	106
Comparison of plasma neurofilament light and total tau as neurodegeneration markers: associations with cognitive and neuroimaging outcomes	99
Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury	97
Kidney function, albuminuria, and their modification by genetic factors and risk of incident dementia in UK Biobank	88
A biomarker-validated time scale in years of disease progression has identified early- and late-onset subgroups in sporadic Alzheimer’s disease	77
The relationship between retinal layers and brain areas in asymptomatic first-degree relatives of sporadic forms of Alzheimer’s disease: an exploratory analysis	75
Molecular insights into sex-specific metabolic alterations in Alzheimer’s mouse brain using multi-omics approach	75
ANU-ADRI scores, tau pathology, and cognition in non-demented adults: the CABLE study	69
High-fat diet-induced atherosclerosis promotes neurodegeneration in the triple transgenic (3 × Tg) mouse model of Alzheimer’s disease associated with chronic platelet activation	66
Impact of potential modifications to Alzheimer’s disease clinical trials in response to disruption by COVID-19: a simulation study	66
Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia	63
The course of primary progressive aphasia diagnosis: a cross-sectional study	62
Blood biomarkers and neurodegeneration in individuals exposed to repetitive head impacts	62
Prevalence and modifiable risk factors for dementia in persons with intellectual disabilities	59
Association of accelerated long-term forgetting and senescence-related blood-borne factors in asymptomatic individuals from families with autosomal dominant Alzheimer’s disease	58
Histone deacetylase inhibitors VPA and WT161 ameliorate the pathological features and cognitive impairments of the APP/PS1 Alzheimer’s disease mouse model by regulating the expression of APP secretase	58
Longitudinal change in ATN biomarkers in cognitively normal individuals	57
Dissecting neural correlates of theory of mind and executive functions in behavioral variant frontotemporal dementia	57

Molecular landscape of the overlap between Alzheimer’s disease and somatic insulin-related diseases	56
Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer’s disease	56
Association of modifiable risk factors with progression to dementia in relation to amyloid and tau pathology	56
Intestinal endogenous metabolites affect neuroinflammation in 5×FAD mice by mediating “gut-brain” axis and the intervention with Chinese Medicine	55
Prognostic model for predicting Alzheimer’s disease conversion using functional connectome manifolds	53
Leading mediators of sex differences in the incidence of dementia in community-dwelling adults in the UK Biobank: a retrospective cohort study	52
Association between untreated and treated blood pressure levels and cognitive decline in community-dwelling middle-aged and older adults in China: a longitudinal study	51
Cerebrospinal fluid α-synuclein adds the risk of cognitive decline and is associated with tau pathology among non-demented older adults	49
Enhancing magnetic resonance imaging-driven Alzheimer’s disease classification performance using generative adversarial learning	48
A novel age-informed approach for genetic association analysis in Alzheimer’s disease	48
The impact of incident stroke on cognitive trajectories in later life	48
Sex-specific associations of kynurenic acid with neopterin in Alzheimer’s disease	47
Tau-related grey matter network breakdown across the Alzheimer’s disease continuum	47
The presence of circulating human apolipoprotein J reduces the occurrence of cerebral microbleeds in a transgenic mouse model with cerebral amyloid angiopathy	46
Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ	45
Lewy Body Dementia Association’s Industry Advisory Council: proceedings of the second annual meeting	44
Is the clinical phenotype impact the prognosis in dementia with Lewy bodies?	43
Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and inflammation in the brain	43