OOIR: Observatory of International Research

Papers

(The TQCC of Biofabrication is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
From microtissues to organs: the future of reconstructive surgery with organ building block-based bioprinting	135
Development of immunocompetent full thickness skin tissue constructs to model skin fibrosis for high-throughput drug screening	98
Microfluidic-based platforms for cell-to-cell communication studies	87
A microvascularized in vitro liver model for disease modeling and drug discovery	75
A biopsy-sized 3D skin model with a perifollicular vascular plexus enables studying immune cell trafficking in the skin	74
In vitro vascularization of hydrogel-based tissue constructs via a combined approach of cell sheet engineering and dynamic perfusion cell culture	69
Enhanced gelatin methacryloyl nanohydroxyapatite hydrogel for high-fidelity 3D printing of bone tissue engineering scaffolds	64
Biochemical and immunomodulatory insights of extracellular matrix from decellularized human whole cervix: recellularization and in vivo ECM remodeling interplay	60
A scalable coaxial bioprinting technology for mesenchymal stem cell microfiber fabrication and high extracellular vesicle yield	59
Cell-laden bioink circulation-assisted inkjet-based bioprinting to mitigate cell sedimentation and aggregation	56
Cancer cell migration depends on adjacent ASC and adipose spheroids in a 3D bioprinted breast cancer model	55
3D bioprinted extracellular vesicles for tissue engineering—a perspective	53
3D bioprinted vascularized lung cancer organoid models with underlying disease capable of more precise drug evaluation	53
Suspension bath bioprinting and maturation of anisotropic meniscal constructs	53
Spheroid on-demand printing and drug screening of endothelialized hepatocellular carcinoma model at different stages	52
Study of paraquat-induced pulmonary fibrosis using biomimetic micro-lung chips	51
Formation of functionally robust human neocartilage from multiple donors using highly expanded costochondral cells	51
Biofabricated nanomaterials in sustainable agriculture: insights, challenges and prospects	49
Acetylcholine-loaded nanoparticles protect against doxorubicin-induced toxicity in in vitro cardiac spheroids	49
A 3D-printed blood-brain barrier model with tunable topology and cell-matrix interactions	46
High-throughput microgel biofabrication via air-assisted co-axial jetting for cell encapsulation, 3D bioprinting, and scaffolding applications	45
Biofabrication of 3D breast cancer models for dissecting the cytotoxic response of human T cells expressing engineered MAIT cell receptors	45
Injectable rBMSCs-laden hydrogel microspheres loaded with naringin for osteomyelitis treatment	45
Bilayer silk fibroin/sodium alginate scaffold promotes vascularization and advances inflammation stage in full-thickness wound	45
3D bioprinted cell-laden GrooveNeuroTube: a multifunctional platform for ex vivo neural cell migration and growth studies	45

Fabrication of bioinspired grid-crimp micropatterns by melt electrospinning writing for bone–ligament interface study	44
Influence of asymmetric microchannels in the structure and function of engineered neuronal circuits	44
Biofabrication of a tri-layered 3D-bioprinted CSC-based malignant melanoma model for personalized cancer treatment	43
From local to global matrix organization by fibroblasts: a 4D laser-assisted bioprinting approach	43
In vitro osteogenesis of hMSCs on collagen membranes embedded within LEGO^®-inspired 3D printed PCL constructs for mandibular bone repair	42
The Batch-Resourcing Angiogenesis Tool (BRAT) to enable high-throughput microscopy screening of microvascular networks	42
Support-less ceramic 3D printing of bioceramic structures using a hydrogel bath	42
Cartilage tissue engineering by extrusion bioprinting utilizing porous hyaluronic acid microgel bioinks	42
Biohybrid tensegrity actuator driven by selective contractions of multiple skeletal muscle tissues	41
3D bioprinted in vitro epilepsy models for pharmacological evaluation in temporal lobe epilepsy	41
On-chip human lymph node stromal network for evaluating dendritic cell and T-cell trafficking	41
In vitro circulation model driven by tissue-engineered dome-shaped cardiac tissue	40
Freeform printing of thermoresponsive poly(2-cyclopropyl-oxazoline) as cytocompatible and on-demand dissolving template of hollow channel networks in cell-laden hydrogels	40
A hepatic zonation chip with an oxygen concentration gradient embracing the spatial distribution of metabolic function	40
Fabrication of 3D engineered intestinal tissue producing abundant mucus by air–liquid interface culture using paper-based dual-layer scaffold	38
Recent trends in embedded 3D bioprinting of vascularized tissue constructs	38
Editorial: Special Issue on biofabrication of cartilage, bone and their interface	38
Bioassembly of hemoglobin-loaded photopolymerizable spheroids alleviates hypoxia-induced cell death	38
Endothelial extracellular vesicles enhance vascular self-assembly in engineered human cardiac tissues	38
Scale-out production of extracellular vesicles derived from natural killer cells via mechanical stimulation in a seesaw-motion bioreactor for cancer therapy	37
The bioengineering of perfusable endocrine tissue with anastomosable blood vessels	37
Computer-aided patterning of PCL microspheres to build modular scaffolds featuring improved strength and neovascularized tissue integration	34
Mechanically and biologically promoted cell-laden constructs generated using tissue-specific bioinks for tendon/ligament tissue engineering applications	34
Mimicking sarcolemmal damage in vitro: a contractile 3D model of skeletal muscle for drug testing in Duchenne muscular dystrophy	34
A thermogelling organic-inorganic hybrid hydrogel with excellent printability, shape fidelity and cytocompatibility for 3D bioprinting	34
Testis on a chip—a microfluidic three-dimensional culture system for the development of spermatogenesis in-vitro	34
Pillar electrodes embedded in the skeletal muscle tissue for selective stimulation of biohybrid actuators with increased contractile distance	33
Printing GelMA bioinks: a strategy for building in vitro model to study nanoparticle-based minocycline release and cellular protection under oxidative stress	33
Engineered tumor microspheres via microfluidics and decellularized extracellular matrix for high-throughput organoid-based drug screening	32
Fibrinogen-based cell and spheroid sheets manipulating and delivery for mouse hindlimb ischemia	32
Biofabrication of microstructured bacterial ecosystems using chaotic bioprinting: advancing in vitro research for microbial engineering	32
Enhancement of properties of a cell-laden GelMA hydrogel-based bioink via calcium phosphate phase transition	32
Efficient fabrication of 3D bioprinted functional sensory neurons using an inducible Neurogenin-2 human pluripotent stem cell line	32
Fabrication of a tailor-made conductive polyaniline/ascorbic acid-coated nanofibrous mat as a conductive and antioxidant cell-free cardiac patch	31
Engineering anisotropic tissue analogues: harnessing synergistic potential of extrusion-based bioprinting and extracellular matrix-based bioink	31
Engineering an organoid culture system for enhanced murine and human hematopoietic stem and progenitor cell self-renewal and expansion	30
Pneumatic conveying inkjet bioprinting for the processing of living cells	30
Assessment and process optimization of high throughput biofabrication of immunocompetent breast cancer model for drug screening applications	30
Generating human skeletal myoblast spheroids for vascular myogenic tissue engineering	29
Advances in biomaterials-based tissue engineering for regeneration of female reproductive tissues	28
Efficient one-step immobilization of DNA probes on 1DZnO nanoplatforms targeting a low-mutation region of SARS-CoV-2	28
Development of a bioreactor and volumetric bioprinting protocol to enable perfused culture of biofabricated human epithelial mammary ducts and endothelial constructs	28
Uniform cerebral organoid culture on a pillar plate by simple and reproducible spheroid transfer from an ultralow attachment well plate	28
Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors	28
Recent trends in the development of in vitro 3D kidney models	27
3D bioprinting approaches for spinal cord injury repair	27
Placing biofabrication into the context of human disease modeling	27
Co-axial printing of convoluted proximal tubule for kidney disease modeling	27
Biomimetic human skin model patterned with rete ridges	27
Modular assembly of bioprinted perfusable blood vessel and tracheal epithelium for studying inflammatory respiratory diseases	27

Constraint based Bayesian optimization of bioink precursor: a machine learning framework	26
Constructing high-strength nano-micro fibrous woven scaffolds with native-like anisotropic structure and immunoregulatory function for tendon repair and regeneration	26
Integration of bioprinting advances and biomechanical strategies for in vitro lung modelling	26
Hybrid fabrication of photo-clickable vascular hydrogels with additive manufactured titanium implants for enhanced osseointegration and vascularized bone formation	26
Photoacoustic imaging of 3D-printed vascular networks	26
Fabrication of hierarchically porous trabecular bone replicas via 3D printing with high internal phase emulsions (HIPEs)	26
Complex in vitro models positioned for impact to drug testing in pharma: a review	25
The interface stiffness and topographic feature dictate interfacial invasiveness of cancer spheroids	25
FRESH 3D bioprinting a contractile heart tube using human stem cell-derived cardiomyocytes	25
Core–shell microbead-based 3D vascularized glioma tumor model for effective drug testing	25
Cation-crosslinked κ-carrageenan sub-microgel medium for high-quality embedded bioprinting	25
Local extensional flows promote long-range fiber alignment in 3D collagen hydrogels	24
Development of a high-throughput micropatterned agarose scaffold for consistent and reproducible hPSC-derived liver organoids	24
Long-term in vitro maintenance of plasma cells in a hydrogel-enclosed human bone marrow microphysiological 3D model system	24
Current progress of in vitro vascular models on microfluidic chips	24
Additive manufacturing and performance of bioceramic scaffolds with different hollow strut geometries	24
High resolution melt electro-written scaffolds promote alignment of human skeletal muscle cells	23
A novel solution for real-time in-situ cell distribution monitoring in 3D bioprinting via fluorescence imaging	23
Mimicking tumor microenvironment by 3D bioprinting: 3D cancer modeling	23
Biofabrication of biomimetic undulating microtopography at the dermal-epidermal junction and its effects on the growth and differentiation of epidermal cells	23
In vitro long term differentiation and functionality of three-dimensional bioprinted primary human hepatocytes: application for in vivo	23
Design and bioprinting for tissue interfaces	23
Functional imaging of 3D bioprinted microalgal constructs and simulation of their photosynthetic performance	23
3D printed bioactive coated scaffolds boost osteogenesis and angiogenesis via the regulation of scaffold microstructure	23
Current advances in engineering meniscal tissues: insights into 3D printing, injectable hydrogels and physical stimulation based strategies	23
Targeted micro-heterogeneity in bioinks allows for 3D printing of complex constructs with improved resolution and cell viability	23
3D hydrogel microfibers promote the differentiation of encapsulated neural stem cells and facilitate neuron protection and axon regrowth after complete transactional spinal cord injury	23
3D engineering of diseased blood vessels for integrative in vitro–in silico mechanobiology study	23
Rational design of 3D-printed scaffolds for breast tissue engineering using structural analysis	22
Advancing extrusion-based embedded 3D bioprinting via scientific, engineering, and process innovations	22
Simulating big mechanically-active culture systems (BigMACS) using paired biomechanics-histology FEA modelling to derive mechanobiology design relationships	22
Additive manufacturing of silicon nitride fiber-reinforced polyetheretherketone composites with enhanced mechanical strength and multifunctional bioactivity for load-bearing bone defect repair	22
Novel in situ and rapid self-gelation recombinant collagen-like protein hydrogel for wound regeneration: mediated by metal coordination crosslinking and reinforced by electro-oxidized tea polyphenols	22
Digital light processing-bioprinted poly-NAGA-GelMA-based hydrogel lenticule for precise refractive errors correction	21
Stress-free cell aggregation by using the CEPT cocktail enhances embryoid body and organoid fitness	21
Microfluidic bioprinting as a tool to produce hiPSCs-derived renal organoids	21
Highly compliant biomimetic scaffolds for small diameter tissue-engineered vascular grafts (TEVGs) produced via melt electrowriting (MEW)	21
In vitro three-dimensional volumetric printing of vitreous body models using decellularized extracellular matrix bioink	21
Surface slicing and toolpath planning for in-situ bioprinting of skin implants	21
An open-source bioink database for microextrusion 3D printing	21
Versatile xanthan gum-based support bath material compatible with multiple crosslinking mechanisms: rheological properties, printability, and cytocompatibility study	21
Non-destructive luminescence and PET imaging to monitor tissue microenvironment in microphysiological systems during brain metastasis using dissociated cerebral organoids	21
Incorporating biomechanics as a key evaluation metric for organoids	21
Development of a plasma-based 3D printing system for enhancing the biocompatibility of 3D scaffold	21
A parallelized, perfused 3D triculture model of leukemia for in vitro drug testing of chemotherapeutics	21
Self-assembled innervated vasculature-on-a-chip to study nociception	21
3D bioprinted tumor model with extracellular matrix enhanced bioinks for nanoparticle evaluation	21
In vitro bioprinted 3D model enhancing osteoblast-to-osteocyte differentiation	21
3D bioprinted epicardial patch of GelMA containing VEGF-loaded chitosan nanoparticles and human bone marrow mesenchymal stem cells for the treatment of myocardial infarction	20
High-throughput bioprinting of the nasal epithelium using patient-derived nasal epithelial cells	20
Regolith-supported biofabrication: 3D bioprinting of living, photosynthetically active structures using Lunar and Martian regolith simulants	20
An immunocompetent human kidney on-a-chip model to study renal inflammation and immune-mediated injury	20
Construction of highly vascularized hepatic spheroids of primary hepatocytes via pro-angiogenic strategy in vitro	20
3D melt electrowritten MXene-reinforced scaffolds for tissue engineering applications	20
Comparison study on hyaline cartilage versus fibrocartilage formation in a pig model by using 3D-bioprinted hydrogel and hybrid constructs	19
Using a micro-device with a deformable ceiling to probe stiffness heterogeneities within 3D cell aggregates	19
Calcium supplementation of bioinks reduces shear stress-induced cell damage during bioprinting	19
Soft pneumatic actuators for mimicking multi-axial femoropopliteal artery mechanobiology	18
Biofabrication & cryopreservation of tissue engineered constructs for on-demand applications	18
Fixation method of a single muscle fiber by magnetic force for stretching, transportation, and evaluation of mechanical properties	18
Ionically annealed zwitterionic microgels for bioprinting of cartilaginous constructs	18
Antibacterial, ROS scavenging and angiogenesis promoting ϵ-Polylysine/gelatin based hydrogel containing CTLP to regulate macrophages for pressure ulcer healing	18
Efficient wet-spinning of pre-aligned microtissues for 3D bioprinting complex tissue alignment	18
Bioprinting of pre-vascularized constructs for enhanced in vivo neo-vascularization	18
3D bioprinting in tissue engineering: current state-of-the-art and challenges towards system standardization and clinical translation	18
Recent progress of organ-on-a-chip towards cardiovascular diseases: advanced design, fabrication, and applications	18
Closed-loop vasculature network design for bioprinting large, solid tissue scaffolds	17
Exploring bio-nanomaterials as antibiotic allies to combat antimicrobial resistance	17
Comparison of in-situ versus ex-situ delivery of polyethylenimine-BMP-2 polyplexes for rat calvarial defect repair via intraoperative bioprinting	17
Bio-3D printing with smooth muscle cells derived from human iPSCs via neural crest and its application for the tracheal regeneration	17
A cell bank paradigm for preclinical evaluation of an analogous cellular product for an allogeneic cell therapy	17
Pharmacy 3D printing	17
Tailoring agarose fluid gels for use in suspension bath bioprinting and culture of spheroid-based bioinks	17
Ultrasound standing wave spatial patterning of human umbilical vein endothelial cells for 3D micro-vascular networks formation	17
Engineering strategies for the construction of oriented and functional skeletal muscle tissues	17
Construction of a three-dimensional urothelium on-chip with barrier function based on urinary flow microenvironment	17
Interstitial fluid flow contributes to prostate cancer invasion and migration to bone; study conducted using a novel horizontal flow bioreactor	17