OOIR: Observatory of International Research

Papers

(The TQCC of Biofabrication is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Engineering bioinks for 3D bioprinting	143
Printability in extrusion bioprinting	91
Droplet-based microfluidics in biomedical applications	83
Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications	67
A novel tumor-immune microenvironment (TIME)-on-Chip mimics three dimensional neutrophil-tumor dynamics and neutrophil extracellular traps (NETs)-mediated collective tumor invasion	63
Combinations of photoinitiator and UV absorber for cell-based digital light processing (DLP) bioprinting	62
Biofabrication of endothelial cell, dermal fibroblast, and multilayered keratinocyte layers for skin tissue engineering	61
Modeling the printability of photocuring and strength adjustable hydrogel bioink during projection-based 3D bioprinting	59
GelMA/bioactive silica nanocomposite bioinks for stem cell osteogenic differentiation	58
3D cell-printing of tendon-bone interface using tissue-derived extracellular matrix bioinks for chronic rotator cuff repair	56
Multi-material digital light processing bioprinting of hydrogel-based microfluidic chips	55
Multimaterial bioprinting and combination of processing techniques towards the fabrication of biomimetic tissues and organs	54
Recent advances in 3D bioprinting of musculoskeletal tissues	54
Dynamic hyaluronic acid hydrogel with covalent linked gelatin as an anti-oxidative bioink for cartilage tissue engineering	53
Cartilage tissue engineering by extrusion bioprinting utilizing porous hyaluronic acid microgel bioinks	50
Mimicking tumor microenvironment by 3D bioprinting: 3D cancer modeling	48
3D bioprinted, vascularized neuroblastoma tumor environment in fluidic chip devices for precision medicine drug testing	48
Bio-3D printing iPSC-derived human chondrocytes for articular cartilage regeneration	48
Recent advancements in the bioprinting of vascular grafts	45
High throughput direct 3D bioprinting in multiwell plates	45
Alginate–gelatin–Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models	44
A biofabrication method to align cells within bioprinted photocrosslinkable and cell-degradable hydrogel constructs via embedded fibers	41
Green electrospinning for biomaterials and biofabrication	41
Recapitulating monocyte extravasation to the synovium in an organotypic microfluidic model of the articular joint	41
Fabrication of MSC-laden composites of hyaluronic acid hydrogels reinforced with MEW scaffolds for cartilage repair	40

A targeted rheological bioink development guideline and its systematic correlation with printing behavior	40
A digital light processing 3D printed magnetic bioreactor system using silk magnetic bioink	40
Aspiration-assisted bioprinting of co-cultured osteogenic spheroids for bone tissue engineering	40
On-chip high-definition bioprinting of microvascular structures	40
Combining electrospinning with hot drawing process to fabricate high performance poly (L-lactic acid) nanofiber yarns for advanced nanostructured bio-textiles	39
Enabling peristalsis of human colon tumor organoids on microfluidic chips	38
Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin	38
Decellularized kidney extracellular matrix bioinks recapitulate renal 3D microenvironment in vitro	37
Bio-instructive hydrogel expands the paracrine potency of mesenchymal stem cells	36
Double network laminarin-boronic/alginate dynamic bioink for 3D bioprinting cell-laden constructs	36
4D bioprintable self-healing hydrogel with shape memory and cryopreserving properties	36
Vascularized adipocyte organoid model using isolated human microvessel fragments	35
FRESH 3D bioprinting a contractile heart tube using human stem cell-derived cardiomyocytes	35
Tunable metacrylated hyaluronic acid-based hybrid bioinks for stereolithography 3D bioprinting	34
Engineered assistive materials for 3D bioprinting: support baths and sacrificial inks	33
A perfusable vascularized full-thickness skin model for potential topical and systemic applications	33
3D bioprinting of molecularly engineered PEG-based hydrogels utilizing gelatin fragments	33
3D bioprinting of dECM/Gel/QCS/nHAp hybrid scaffolds laden with mesenchymal stem cell-derived exosomes to improve angiogenesis and osteogenesis	33
Constructing high-strength nano-micro fibrous woven scaffolds with native-like anisotropic structure and immunoregulatory function for tendon repair and regeneration	32
3D printing of inorganic-biopolymer composites for bone regeneration	32
Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation	32
Aspiration-assisted freeform bioprinting of mesenchymal stem cell spheroids within alginate microgels	31
Improved accuracy and precision of bioprinting through progressive cavity pump-controlled extrusion	31
Towards engineering heart tissues from bioprinted cardiac spheroids	31
Fabrication of microvascular constructs using high resolution electrohydrodynamic inkjet printing	31
Biomimetic and mechanically supportive 3D printed scaffolds for cartilage and osteochondral tissue engineering using photopolymers and digital light processing	31
High throughput microfluidic system with multiple oxygen levels for the study of hypoxia in tumor spheroids	30
Bioink with cartilage-derived extracellular matrix microfibers enables spatial control of vascular capillary formation in bioprinted constructs	30
Polydopamine-coated polycaprolactone/carbon nanotube fibrous scaffolds loaded with brain-derived neurotrophic factor for peripheral nerve regeneration	29
Bioprinting of alginate-carboxymethyl chitosan scaffolds for enamel tissue engineering in vitro	29
Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform	29
Scalable fabrication of renal spheroids and nephron-like tubules by bioprinting and controlled self-assembly of epithelial cells	29
Bioactive Sr²⁺/Fe³⁺ co-substituted hydroxyapatite in cryogenically 3D printed porous scaffolds for bone tissue engineering	29
Bioengineered in vitro 3D model of myotonic dystrophy type 1 human skeletal muscle	29
Magnetic molding of tumor spheroids: emerging model for cancer screening	29
A novel extrusion-based 3D bioprinting system for skeletal muscle tissue engineering	28
Core–shell bioprinting of vascularized in vitro liver sinusoid models	28
Printability and bio-functionality of a shear thinning methacrylated xanthan–gelatin composite bioink	28
Scaffold microarchitecture regulates angiogenesis and the regeneration of large bone defects	28
Neural stem cell delivery using brain-derived tissue-specific bioink for recovering from traumatic brain injury	28
Simultaneous 2D and 3D cell culture array for multicellular geometry, drug discovery and tumor microenvironment reconstruction	27
Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications	27
Architected fibrous scaffolds for engineering anisotropic tissues	27
An injectable bioink with rapid prototyping in the air and in-situ mild polymerization for 3D bioprinting	27
Low temperature hybrid 3D printing of hierarchically porous bone tissue engineering scaffolds with in situ delivery of osteogenic peptide and mesenchymal stem cells	27
Testis on a chip—a microfluidic three-dimensional culture system for the development of spermatogenesis in-vitro	27
3D printing of sacrificial thioester elastomers using digital light processing for templating 3D organoid structures in soft biomatrices	27
Enhanced vascularization and de novo tissue formation in hydrogels made of engineered RGD-tagged spider silk proteins in the arteriovenous loop model	26
Human gelatin-based composite hydrogels for osteochondral tissue engineering and their adaptation into bioinks for extrusion, inkjet, and digital light processing bioprinting	26
3D-printed bioceramic scaffolds with Fe₃S₄ microflowers for magnetothermal and chemodynamic therapy of bone tumor and regeneration of bone defects	26

3D bioprinted tumor model with extracellular matrix enhanced bioinks for nanoparticle evaluation	26
Core–shell bioprinting as a strategy to apply differentiation factors in a spatially defined manner inside osteochondral tissue substitutes	25
Valve-based consecutive bioprinting method for multimaterial tissue-like constructs with controllable interfaces	25
Controllable assembly of skeletal muscle-like bundles through 3D bioprinting	25
Bioprinted microvasculature: progressing from structure to function	25
BoneMA—synthesis and characterization of a methacrylated bone-derived hydrogel for bioprinting of in-vitro vascularized tissue constructs	25
In vivo organized neovascularization induced by 3D bioprinted endothelial-derived extracellular vesicles	24
A multifunctional micropore-forming bioink with enhanced anti-bacterial and anti-inflammatory properties	24
Study of the process-induced cell damage in forced extrusion bioprinting	24
Long-term mechanical loading is required for the formation of 3D bioprinted functional osteocyte bone organoids	24
Bilayer silk fibroin/sodium alginate scaffold promotes vascularization and advances inflammation stage in full-thickness wound	24
3D bioprinting of osteon-mimetic scaffolds with hierarchical microchannels for vascularized bone tissue regeneration	23
3D bioassembly of cell-instructive chondrogenic and osteogenic hydrogel microspheres containing allogeneic stem cells for hybrid biofabrication of osteochondral constructs	23
Compensating the cell-induced light scattering effect in light-based bioprinting using deep learning	23
Micro-electrode channel guide (µECG) technology: an online method for continuous electrical recording in a human beating heart-on-chip	23
Next generation human brain models: engineered flat brain organoids featuring gyrification	23
Stem cell spheroid engineering with osteoinductive and ROS scavenging nanofibers for bone regeneration	23
Biofabrication of vasculature in microphysiological models of bone	23
Hybrid extracellular vesicles-liposome incorporated advanced bioink to deliver microRNA	23
From local to global matrix organization by fibroblasts: a 4D laser-assisted bioprinting approach	22
Micropatterned conductive elastomer patch based on poly (glycerol sebacate)-graphene for cardiac tissue repair	22
User-friendly microfluidic manufacturing of hydrogel microspheres with sharp needle	22
Smart acoustic 3D cell construct assembly with high-resolution	21
Mechanically and biologically promoted cell-laden constructs generated using tissue-specific bioinks for tendon/ligament tissue engineering applications	21
Mild formation of core–shell hydrogel microcapsules for cell encapsulation	21
A 3D bioprinted hybrid encapsulation system for delivery of human pluripotent stem cell-derived pancreatic islet-like aggregates	21
Biofabrication of muscle fibers enhanced with plant viral nanoparticles using surface chaotic flows	21
An engineered neurovascular unit for modeling neuroinflammation	20
3D bioprinted vascularized lung cancer organoid models with underlying disease capable of more precise drug evaluation	20
In-situ mineralized homogeneous collagen-based scaffolds for potential guided bone regeneration	20
Thin and stretchable extracellular matrix (ECM) membrane reinforced by nanofiber scaffolds for developing in vitro barrier models	20
Bio-inspired zonal-structured matrices for bone-cartilage interface engineering	20
A microphysiological system combining electrospun fibers and electrical stimulation for the maturation of highly anisotropic cardiac tissue	20
Catechol functionalized ink system and thrombin-free fibrin gel for fabricating cellular constructs with mechanical support and inner micro channels	20
Cell-laden bioink circulation-assisted inkjet-based bioprinting to mitigate cell sedimentation and aggregation	19
The spatial arrangement of cells in a 3D-printed biomimetic spinal cord promotes directional differentiation and repairs the motor function after spinal cord injury	19
Calcium supplementation of bioinks reduces shear stress-induced cell damage during bioprinting	19
3D bioprinted human iPSC-derived somatosensory constructs with functional and highly purified sensory neuron networks	18
Luminal flow actuation generates coupled shear and strain in a microvessel-on-chip	18
Development of a biomimetic arch-like 3D bioprinted construct for cartilage regeneration using gelatin methacryloyl and silk fibroin-gelatin bioinks	18
Enhancing islet transplantation using a biocompatible collagen-PDMS bioscaffold enriched with dexamethasone-microplates	18
An interfacial self-assembling bioink for the manufacturing of capillary-like structures with tuneable and anisotropic permeability	18
Electroceuticals for peripheral nerve regeneration	18
Egg white improves the biological properties of an alginate-methylcellulose bioink for 3D bioprinting of volumetric bone constructs	17
Deployable extrusion bioprinting of compartmental tumoroids with cancer associated fibroblasts for immune cell interactions	17
Hierarchical biomaterials via photopatterning-enhanced direct ink writing	17
Bioprinting of biomimetic self-organised cartilage with a supporting joint fixation device	17
Biofabrication of a tri-layered 3D-bioprinted CSC-based malignant melanoma model for personalized cancer treatment	17
Microfluidic-assisted bioprinting of tissues and organoids at high cell concentrations	17
Perfusion bioreactor enabled fluid-derived shear stress conditions for novel bone metastatic prostate cancer testbed	17
Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses	16
3D stem cell-laden artificial endometrium: successful endometrial regeneration and pregnancy	16
Transplantation of 3D bio-printed cardiac mesh improves cardiac function and vessel formation via ANGPT1/Tie2 pathway in rats with acute myocardial infarction	16
3D printing of sponge spicules-inspired flexible bioceramic-based scaffolds	16
A Parkinson’s disease model composed of 3D bioprinted dopaminergic neurons within a biomimetic peptide scaffold	16
An enhanced periosteum structure/function dual mimicking membrane for in-situ restorations of periosteum and bone	16
Engineering the fate and function of human T-Cells via 3D bioprinting	16
3D bioprinted autologous bone particle scaffolds for cranioplasty promote bone regeneration with both implanted and native BMSCs	16
A versatile embedding medium for freeform bioprinting with multi-crosslinking methods	15
Computational investigation of interface printing patterns within 3D printed multilayered scaffolds for osteochondral tissue engineering	15
Fabrication of a dual-layer cell-laden tubular scaffold for nerve regeneration and bile duct reconstruction	15
miRNA induced 3D bioprinted-heterotypic osteochondral interface	15
Large-scale single-cell encapsulation in microgels through metastable droplet-templating combined with microfluidic-integration	15
3D bioprinted tissue-specific spheroidal multicellular microarchitectures for advanced cell therapy	15
A multimodal 3D neuro-microphysiological system with neurite-trapping microelectrodes	15
Degradable calcium deficient hydroxyapatite/poly(lactic-glycolic acid copolymer) bilayer scaffold through integral molding 3D printing for bone defect repair	15
Three-dimensional bioprinted BMSCs-laden highly adhesive artificial periosteum containing gelatin-dopamine and graphene oxide nanosheets promoting bone defect repair	15
Biofabrication of 3D breast cancer models for dissecting the cytotoxic response of human T cells expressing engineered MAIT cell receptors	15
Cellulose-based scaffolds enhance pseudoislets formation and functionality	15
In vitro breast cancer model with patient-specific morphological features for personalized medicine	15
Development of a high-throughput micropatterned agarose scaffold for consistent and reproducible hPSC-derived liver organoids	15
In vitro and in vivo characterization of a novel tricalcium silicate-based ink for bone regeneration using laser-assisted bioprinting	15
Scale-out production of extracellular vesicles derived from natural killer cells via mechanical stimulation in a seesaw-motion bioreactor for cancer therapy	15
Particulate ECM biomaterial ink is 3D printed and naturally crosslinked to form structurally-layered and lubricated cartilage tissue mimics	15
A 3D-printed microfluidic platform for simulating the effects of CPAP on the nasal epithelium	15
Bisulfite-initiated crosslinking of gelatin methacryloyl hydrogels for embedded 3D bioprinting	15
3D-bioengineered model of human skeletal muscle tissue with phenotypic features of aging for drug testing purposes	15