OOIR: Observatory of International Research

Papers

(The TQCC of Biofabrication is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-07-01 to 2024-07-01.)

Article	Citations
Engineering bioinks for 3D bioprinting	130
3D printed oxidized alginate-gelatin bioink provides guidance for C2C12 muscle precursor cell orientation and differentiation via shear stress during bioprinting	85
Improving alginate printability for biofabrication: establishment of a universal and homogeneous pre-crosslinking technique	85
Printability in extrusion bioprinting	82
Droplet-based microfluidics in biomedical applications	68
Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications	60
3D Printing of large-scale and highly porous biodegradable tissue engineering scaffolds from poly(trimethylene-carbonate) using two-photon-polymerization	60
Biofabrication of endothelial cell, dermal fibroblast, and multilayered keratinocyte layers for skin tissue engineering	58
GelMA/bioactive silica nanocomposite bioinks for stem cell osteogenic differentiation	56
A novel tumor-immune microenvironment (TIME)-on-Chip mimics three dimensional neutrophil-tumor dynamics and neutrophil extracellular traps (NETs)-mediated collective tumor invasion	56
Combinations of photoinitiator and UV absorber for cell-based digital light processing (DLP) bioprinting	54
Dynamic hyaluronic acid hydrogel with covalent linked gelatin as an anti-oxidative bioink for cartilage tissue engineering	52
Recent advances in 3D bioprinting of musculoskeletal tissues	50
Modeling the printability of photocuring and strength adjustable hydrogel bioink during projection-based 3D bioprinting	49
3D printed titanium scaffolds with homogeneous diamond-like structures mimicking that of the osteocyte microenvironment and its bone regeneration study	48
3D cell-printing of tendon-bone interface using tissue-derived extracellular matrix bioinks for chronic rotator cuff repair	48
Self-crosslinking hyaluronic acid–carboxymethylcellulose hydrogel enhances multilayered 3D-printed construct shape integrity and mechanical stability for soft tissue engineering	48
Dual drug delivery system based on pH-sensitive silk fibroin/alginate nanoparticles entrapped in PNIPAM hydrogel for treating severe infected burn wound	47
Cartilage tissue engineering by extrusion bioprinting utilizing porous hyaluronic acid microgel bioinks	47
Multi-material digital light processing bioprinting of hydrogel-based microfluidic chips	47
Sound-induced morphogenesis of multicellular systems for rapid orchestration of vascular networks	46
Multimaterial bioprinting and combination of processing techniques towards the fabrication of biomimetic tissues and organs	44
Bio-3D printing iPSC-derived human chondrocytes for articular cartilage regeneration	43
High throughput direct 3D bioprinting in multiwell plates	43
Recent advancements in the bioprinting of vascular grafts	42

Fabrication of MSC-laden composites of hyaluronic acid hydrogels reinforced with MEW scaffolds for cartilage repair	39
A biofabrication method to align cells within bioprinted photocrosslinkable and cell-degradable hydrogel constructs via embedded fibers	39
Aspiration-assisted bioprinting of co-cultured osteogenic spheroids for bone tissue engineering	38
Alginate–gelatin–Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models	38
A targeted rheological bioink development guideline and its systematic correlation with printing behavior	37
On-chip high-definition bioprinting of microvascular structures	37
Recapitulating monocyte extravasation to the synovium in an organotypic microfluidic model of the articular joint	37
Green electrospinning for biomaterials and biofabrication	36
Vascularized adipocyte organoid model using isolated human microvessel fragments	35
Bioprinting of an osteocyte network for biomimetic mineralization	35
A digital light processing 3D printed magnetic bioreactor system using silk magnetic bioink	35
Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin	35
Mimicking tumor microenvironment by 3D bioprinting: 3D cancer modeling	34
3D bioprinted, vascularized neuroblastoma tumor environment in fluidic chip devices for precision medicine drug testing	34
4D bioprintable self-healing hydrogel with shape memory and cryopreserving properties	34
Double network laminarin-boronic/alginate dynamic bioink for 3D bioprinting cell-laden constructs	34
Combining electrospinning with hot drawing process to fabricate high performance poly (L-lactic acid) nanofiber yarns for advanced nanostructured bio-textiles	34
Bio-instructive hydrogel expands the paracrine potency of mesenchymal stem cells	33
Tunable metacrylated hyaluronic acid-based hybrid bioinks for stereolithography 3D bioprinting	33
Enabling peristalsis of human colon tumor organoids on microfluidic chips	33
Decellularized kidney extracellular matrix bioinks recapitulate renal 3D microenvironment in vitro	32
FRESH 3D bioprinting a contractile heart tube using human stem cell-derived cardiomyocytes	31
Towards engineering heart tissues from bioprinted cardiac spheroids	30
Improved accuracy and precision of bioprinting through progressive cavity pump-controlled extrusion	29
High throughput microfluidic system with multiple oxygen levels for the study of hypoxia in tumor spheroids	29
Bioengineered in vitro 3D model of myotonic dystrophy type 1 human skeletal muscle	29
Bioactive Sr²⁺/Fe³⁺ co-substituted hydroxyapatite in cryogenically 3D printed porous scaffolds for bone tissue engineering	29
3D bioprinting of molecularly engineered PEG-based hydrogels utilizing gelatin fragments	29
Aspiration-assisted freeform bioprinting of mesenchymal stem cell spheroids within alginate microgels	29
Engineered assistive materials for 3D bioprinting: support baths and sacrificial inks	28
3D printing of inorganic-biopolymer composites for bone regeneration	28
A perfusable vascularized full-thickness skin model for potential topical and systemic applications	28
An injectable bioink with rapid prototyping in the air and in-situ mild polymerization for 3D bioprinting	27
Biomimetic and mechanically supportive 3D printed scaffolds for cartilage and osteochondral tissue engineering using photopolymers and digital light processing	27
Magnetic molding of tumor spheroids: emerging model for cancer screening	27
Fabrication of microvascular constructs using high resolution electrohydrodynamic inkjet printing	27
Scalable fabrication of renal spheroids and nephron-like tubules by bioprinting and controlled self-assembly of epithelial cells	26
3D bioprinting of dECM/Gel/QCS/nHAp hybrid scaffolds laden with mesenchymal stem cell-derived exosomes to improve angiogenesis and osteogenesis	26
3D bioprinted tumor model with extracellular matrix enhanced bioinks for nanoparticle evaluation	26
Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform	26
Bioink with cartilage-derived extracellular matrix microfibers enables spatial control of vascular capillary formation in bioprinted constructs	26
Neural stem cell delivery using brain-derived tissue-specific bioink for recovering from traumatic brain injury	26
3D printing of sacrificial thioester elastomers using digital light processing for templating 3D organoid structures in soft biomatrices	25
Enhanced vascularization and de novo tissue formation in hydrogels made of engineered RGD-tagged spider silk proteins in the arteriovenous loop model	25
Bioprinting of alginate-carboxymethyl chitosan scaffolds for enamel tissue engineering in vitro	25
Printability and bio-functionality of a shear thinning methacrylated xanthan–gelatin composite bioink	25
Bioprinted microvasculature: progressing from structure to function	25
Scaffold microarchitecture regulates angiogenesis and the regeneration of large bone defects	25
Core–shell bioprinting of vascularized in vitro liver sinusoid models	25
Simultaneous 2D and 3D cell culture array for multicellular geometry, drug discovery and tumor microenvironment reconstruction	25

Core–shell bioprinting as a strategy to apply differentiation factors in a spatially defined manner inside osteochondral tissue substitutes	24
Polydopamine-coated polycaprolactone/carbon nanotube fibrous scaffolds loaded with brain-derived neurotrophic factor for peripheral nerve regeneration	24
Architected fibrous scaffolds for engineering anisotropic tissues	24
Human gelatin-based composite hydrogels for osteochondral tissue engineering and their adaptation into bioinks for extrusion, inkjet, and digital light processing bioprinting	24
Constructing high-strength nano-micro fibrous woven scaffolds with native-like anisotropic structure and immunoregulatory function for tendon repair and regeneration	24
BoneMA—synthesis and characterization of a methacrylated bone-derived hydrogel for bioprinting of in-vitro vascularized tissue constructs	24
Controllable assembly of skeletal muscle-like bundles through 3D bioprinting	23
Bilayer silk fibroin/sodium alginate scaffold promotes vascularization and advances inflammation stage in full-thickness wound	23
A multifunctional micropore-forming bioink with enhanced anti-bacterial and anti-inflammatory properties	23
Low temperature hybrid 3D printing of hierarchically porous bone tissue engineering scaffolds with in situ delivery of osteogenic peptide and mesenchymal stem cells	23
3D-printed bioceramic scaffolds with Fe₃S₄ microflowers for magnetothermal and chemodynamic therapy of bone tumor and regeneration of bone defects	23
Valve-based consecutive bioprinting method for multimaterial tissue-like constructs with controllable interfaces	23
Next generation human brain models: engineered flat brain organoids featuring gyrification	23
Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation	23
Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications	22
A novel extrusion-based 3D bioprinting system for skeletal muscle tissue engineering	22
A simplified yet enhanced and versatile microfluidic platform for cyclic cell stretching on an elastic polymer	22
Micro-electrode channel guide (µECG) technology: an online method for continuous electrical recording in a human beating heart-on-chip	22
3D bioassembly of cell-instructive chondrogenic and osteogenic hydrogel microspheres containing allogeneic stem cells for hybrid biofabrication of osteochondral constructs	22
Angiogenic factors secreted from human ASC spheroids entrapped in an alginate-based hierarchical structure via combined 3D printing/electrospinning system	22
Long-term mechanical loading is required for the formation of 3D bioprinted functional osteocyte bone organoids	22
Testis on a chip—a microfluidic three-dimensional culture system for the development of spermatogenesis in-vitro	22
Rapid multilayer microfabrication for modeling organotropic metastasis in breast cancer	21
Hybrid extracellular vesicles-liposome incorporated advanced bioink to deliver microRNA	21
1D and 2D error assessment and correction for extrusion-based bioprinting using process sensing and control strategies	21
User-friendly microfluidic manufacturing of hydrogel microspheres with sharp needle	20
Study of the process-induced cell damage in forced extrusion bioprinting	20
Expanding sacrificially printed microfluidic channel-embedded paper devices for construction of volumetric tissue models in vitro	20
Compensating the cell-induced light scattering effect in light-based bioprinting using deep learning	20
Biofabrication of vasculature in microphysiological models of bone	20
Development of a novel dual reproductive organ on a chip: recapitulating bidirectional endocrine crosstalk between the uterine endometrium and the ovary	20
Coaxial printing of double-layered and free-standing blood vessel analogues without ultraviolet illumination for high-volume vascularised tissue	20
Micropatterned conductive elastomer patch based on poly (glycerol sebacate)-graphene for cardiac tissue repair	20
In vivo organized neovascularization induced by 3D bioprinted endothelial-derived extracellular vesicles	20
Mechanically and biologically promoted cell-laden constructs generated using tissue-specific bioinks for tendon/ligament tissue engineering applications	20
Direct extrusion of individually encapsulated endothelial and smooth muscle cells mimicking blood vessel structures and vascular native cell alignment	20
Bio-inspired zonal-structured matrices for bone-cartilage interface engineering	20
Stem cell spheroid engineering with osteoinductive and ROS scavenging nanofibers for bone regeneration	19
Mild formation of core–shell hydrogel microcapsules for cell encapsulation	19
3D bioprinting of osteon-mimetic scaffolds with hierarchical microchannels for vascularized bone tissue regeneration	19
Biofabrication of muscle fibers enhanced with plant viral nanoparticles using surface chaotic flows	19
A microphysiological system combining electrospun fibers and electrical stimulation for the maturation of highly anisotropic cardiac tissue	18
An interfacial self-assembling bioink for the manufacturing of capillary-like structures with tuneable and anisotropic permeability	18
The spatial arrangement of cells in a 3D-printed biomimetic spinal cord promotes directional differentiation and repairs the motor function after spinal cord injury	18
A 3D bioprinted hybrid encapsulation system for delivery of human pluripotent stem cell-derived pancreatic islet-like aggregates	18
Microfluidic-assisted bioprinting of tissues and organoids at high cell concentrations	17
An engineered neurovascular unit for modeling neuroinflammation	17
Calcium supplementation of bioinks reduces shear stress-induced cell damage during bioprinting	17
Enhancing islet transplantation using a biocompatible collagen-PDMS bioscaffold enriched with dexamethasone-microplates	17
Smart acoustic 3D cell construct assembly with high-resolution	17
In-situ mineralized homogeneous collagen-based scaffolds for potential guided bone regeneration	17
Thin and stretchable extracellular matrix (ECM) membrane reinforced by nanofiber scaffolds for developing in vitro barrier models	17
Perfusion bioreactor enabled fluid-derived shear stress conditions for novel bone metastatic prostate cancer testbed	17