OOIR: Observatory of International Research

Papers

(The TQCC of Biofabrication is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Optimizing extrusion-based 3D bioprinting of plant cells with enhanced resolution and cell viability	148
An open-source bioink database for microextrusion 3D printing	103
In vitro vascularization of hydrogel-based tissue constructs via a combined approach of cell sheet engineering and dynamic perfusion cell culture	88
Reducing retraction in engineered tissues through design of sequential growth factor treatment	70
Versatile xanthan gum-based support bath material compatible with multiple crosslinking mechanisms: rheological properties, printability, and cytocompatibility study	67
Norbornene-functionalized methylcellulose as a thermo- and photo-responsive bioink	65
Embedded 3D printing of dilute particle suspensions into dense complex tissue fibers using shear thinning xanthan baths	64
Silk fibroin increases the elasticity of alginate-gelatin hydrogels and regulates cardiac cell contractile function in cardiac bioinks	63
Stress-free cell aggregation by using the CEPT cocktail enhances embryoid body and organoid fitness	63
FRESH-based 3D bioprinting of complex biological geometries using chitosan bioink	63
Suturable elastomeric tubular grafts with patterned porosity for rapid vascularization of 3D constructs	62
Bio-inspired zonal-structured matrices for bone-cartilage interface engineering	61
3D bioprinted tumor model with extracellular matrix enhanced bioinks for nanoparticle evaluation	58
Biomimetic and mechanically supportive 3D printed scaffolds for cartilage and osteochondral tissue engineering using photopolymers and digital light processing	56
Engineering liver microtissues to study the fusion of HepG2 with mesenchymal stem cells and invasive potential of fused cells	54
miRNA induced co-differentiation and cross-talk of adipose tissue-derived progenitor cells for 3D heterotypic pre-vascularized bone formation	54
A glomerulus chip with spherically twisted cell-laden hollow fibers as glomerular capillary tufts	51
A microvascularized in vitro liver model for disease modeling and drug discovery	49
Sensor macrophages derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs	48
Microfluidic-based platforms for cell-to-cell communication studies	48
Installation of click-type functional groups enable the creation of an additive manufactured construct for the osteochondral interface	44
hiPSC-derived macrophages improve drug sensitivity and selectivity in a macrophage-incorporating organoid culture model	44
Perichondrium-inspired permeable nanofibrous tube well promoting differentiation of hiPSC-derived pellet toward hyaline-like cartilage pellet	44
Bioprinted microvasculature: progressing from structure to function	41
Effects of transglutaminase cross-linking process on printability of gelatin microgel-gelatin solution composite bioink	41

3D bioprinted autologous bone particle scaffolds for cranioplasty promote bone regeneration with both implanted and native BMSCs	40
Design of a versatile microfluidic device for imaging precision-cut-tissue slices	40
Towards engineering heart tissues from bioprinted cardiac spheroids	40
Engineering pore-enriched and pre-vascularized volumetric constructs for enhanced blood glucose regulation in type 1 diabetes therapy	39
Lung dECM matrikine-based hydrogel reverses bleomycin-induced pulmonary fibrosis by suppressing M2 macrophage polarization	38
Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin	38
Dual-core coaxial bioprinting of double-channel constructs with a potential for perfusion and interaction of cells	37
Compensating the cell-induced light scattering effect in light-based bioprinting using deep learning	37
Combinations of photoinitiator and UV absorber for cell-based digital light processing (DLP) bioprinting	36
Bioactive Sr²⁺/Fe³⁺ co-substituted hydroxyapatite in cryogenically 3D printed porous scaffolds for bone tissue engineering	36
Bioengineering of a scaffold-less three-dimensional tissue using net mould	36
Hydrodynamic shear stress’ impact on mammalian cell properties and its applications in 3D bioprinting	35
Efficient hepatic differentiation of hydrogel microsphere-encapsulated human pluripotent stem cells for engineering prevascularized liver tissue	35
Suspension bath bioprinting and maturation of anisotropic meniscal constructs	34
Self-assembled innervated vasculature-on-a-chip to study nociception	33
An injectable and 3D printable pro-chondrogenic hyaluronic acid and collagen type II composite hydrogel for the repair of articular cartilage defects	33
3D bioprinted endothelial cell-microglia coculture for diabetic retinopathy modeling	32
High-resolution 3D printing of angle-ply annulus fibrosus scaffolds for intervertebral disc regeneration	32
Cancer cell migration depends on adjacent ASC and adipose spheroids in a 3D bioprinted breast cancer model	32
Organoid models: the future companions of personalized drug development	32
Microphysiological systems to study colorectal cancer: state-of-the-art	31
A capsule-based scaffold incorporating decellularized extracellular matrix and curcumin for islet beta cell therapy in type 1 diabetes mellitus	31
Gravity-based patterning of osteogenic factors to preserve bone structure after osteochondral injury in a large animal model	31
3D vascularized microphysiological system for investigation of tumor-endothelial crosstalk in anti-cancer drug resistance	31
Bioreactor-based stem cell therapy for liver fibrosis	31
Aspiration-assisted freeform bioprinting of mesenchymal stem cell spheroids within alginate microgels	30
3D bioprinted extracellular vesicles for tissue engineering—a perspective	30
A novel membrane-on-chip guides morphogenesis for the reconstruction of the intestinal crypt-villus axis	30
High throughput microfluidic system with multiple oxygen levels for the study of hypoxia in tumor spheroids	30
A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction	29
Spheroid on-demand printing and drug screening of endothelialized hepatocellular carcinoma model at different stages	29
An innovative 4D printing approach for fabrication of anisotropic collagen scaffolds	29
An injectable bioink with rapid prototyping in the air and in-situ mild polymerization for 3D bioprinting	29
3D-bioengineered model of human skeletal muscle tissue with phenotypic features of aging for drug testing purposes	29
3D engineering of diseased blood vessels for integrative in vitro–in silico mechanobiology study	29
Modeling the printability of photocuring and strength adjustable hydrogel bioink during projection-based 3D bioprinting	28
Fish scale containing alginate dialdehyde-gelatin bioink for bone tissue engineering	28
Pulsed electromagnetic field-assisted reduced graphene oxide composite 3D printed nerve scaffold promotes sciatic nerve regeneration in rats	28
Dynamic hyaluronic acid hydrogel with covalent linked gelatin as an anti-oxidative bioink for cartilage tissue engineering	28
Nucleus pulposus cell-derived efficient microcarrier for intervertebral disc tissue engineering	28
Analysis of bioprinting strategies for skin diseases and injuries through structural and temporal dynamics: historical perspectives, research hotspots, and emerging trends	27
Alginate–gelatin–Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models	27
In vitro breast cancer model with patient-specific morphological features for personalized medicine	27
Hierarchical biomaterials via photopatterning-enhanced direct ink writing	27
Mild formation of core–shell hydrogel microcapsules for cell encapsulation	27
A scalable coaxial bioprinting technology for mesenchymal stem cell microfiber fabrication and high extracellular vesicle yield	27
Aqueous two-phase deposition and fibrinolysis of fibroblast-laden fibrin micro-scaffolds	27
Simultaneous 2D and 3D cell culture array for multicellular geometry, drug discovery and tumor microenvironment reconstruction	26
3D bioprinted vascularized lung cancer organoid models with underlying disease capable of more precise drug evaluation	26
Bioprinting of alginate-carboxymethyl chitosan scaffolds for enamel tissue engineering in vitro	26

Valve-based consecutive bioprinting method for multimaterial tissue-like constructs with controllable interfaces	25
3D bioprinting platform development for high-throughput cancer organoid models construction and drug evaluation	25
Micropatterned conductive elastomer patch based on poly (glycerol sebacate)-graphene for cardiac tissue repair	25
Combining rotary wet-spinning biofabrication and electro-mechanical stimulation for the in vitro production of functional myo-substitutes	25
In situ biosensing technologies for an organ-on-a-chip	24
Biofabrication of biomimetic undulating microtopography at the dermal-epidermal junction and its effects on the growth and differentiation of epidermal cells	24
Size- and density-dependent acoustic differential bioassembly of spatially-defined heterocellular architecture	24
3D bioprinted tissue-specific spheroidal multicellular microarchitectures for advanced cell therapy	24
A novel tumor-immune microenvironment (TIME)-on-Chip mimics three dimensional neutrophil-tumor dynamics and neutrophil extracellular traps (NETs)-mediated collective tumor invasion	23
Biochemical and immunomodulatory insights of extracellular matrix from decellularized human whole cervix: recellularization and in vivo ECM remodeling interplay	23
3D-bioprintable endothelial cell-laden sacrificial ink for fabrication of microvessel networks	23
3D cell-printing of tendon-bone interface using tissue-derived extracellular matrix bioinks for chronic rotator cuff repair	23
Fabrication of microvascular constructs using high resolution electrohydrodynamic inkjet printing	23
A perfusable, vascularized kidney organoid-on-chip model	23
Cell-laden bioink circulation-assisted inkjet-based bioprinting to mitigate cell sedimentation and aggregation	23
Renal proximal tubule-on-a-chip in PDMS: fabrication, functionalization, and RPTEC:HUVEC co-culture evaluation	23
Novel in situ and rapid self-gelation recombinant collagen-like protein hydrogel for wound regeneration: mediated by metal coordination crosslinking and reinforced by electro-oxidized tea polyphenols	22
Corrigendum: Biofabrication of cell-free dual drug-releasing biomimetic scaffolds for meniscal regeneration (2022 Biofabrication 14 015001)	22
Nano-biofertilizers: utilizing nanopolymers as coating matrix—a comprehensive review	22
Bioprinting a resilient and transparent cornea stroma equivalent: harnessing dual crosslinking strategy with decellularized cornea matrix and silk fibroin hybrid	22
Cell-assembled extracellular matrix (CAM): a human biopaper for the biofabrication of pre-vascularized tissues able to connect to the host circulation in vivo	21
Enabling peristalsis of human colon tumor organoids on microfluidic chips	21
Automated production of nerve repair constructs containing endothelial cell tube-like structures	21
Implementing microfluidic flow device model in utilizing dural substitutes as pulp capping materials for vital pulp therapy	21
Hybrid 3D bioprinting for advanced tissue-engineered trachea: merging fused deposition modeling (FDM) and top–down digital light processing (DLP)	21
A biopsy-sized 3D skin model with a perifollicular vascular plexus enables studying immune cell trafficking in the skin	21
Development of immunocompetent full thickness skin tissue constructs to model skin fibrosis for high-throughput drug screening	20
Rational design of 3D-printed scaffolds for breast tissue engineering using structural analysis	20
Advancement of 3D biofabrication in repairing and regeneration of cartilage defects	20
High-throughput bioprinting of the nasal epithelium using patient-derived nasal epithelial cells	20
A microphysiological assay for studying T-cell chemotaxis, trafficking and tumor killing	20
One-step bioprinting of endothelialized, self-supporting arterial and venous networks	20
Long-term in vitro culture of 3D brain tissue model based on chitosan thermogel	20
A deep and permeable nanofibrous oval-shaped microwell array for the stable formation of viable and functional spheroids	19
Calcium supplementation of bioinks reduces shear stress-induced cell damage during bioprinting	19
Fabrication of heterocellular spheroids with controllable core-shell structure using inertial focusing effect for scaffold-free 3D cell culture models	19
Spermatogenesis in mouse testicular organoids with testis-specific architecture, improved germ cell survival and testosterone production	18
Bilayer silk fibroin/sodium alginate scaffold promotes vascularization and advances inflammation stage in full-thickness wound	18
A parallelized, perfused 3D triculture model of leukemia for in vitro drug testing of chemotherapeutics	18
Tunable metacrylated hyaluronic acid-based hybrid bioinks for stereolithography 3D bioprinting	18
Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease	18
Accessible dynamic micropatterns in monolayer cultures via modified desktop xurography	17
A 3D-printed blood-brain barrier model with tunable topology and cell-matrix interactions	17
In vitro bioprinted 3D model enhancing osteoblast-to-osteocyte differentiation	17
A long-term storable gel-laden chip composite built in a multi-well plate enabling in situ cell encapsulation for high-throughput liver model	17
An immunocompetent human kidney on-a-chip model to study renal inflammation and immune-mediated injury	17
A handheld bioprinter for multi-material printing of complex constructs	17
Highly compliant biomimetic scaffolds for small diameter tissue-engineered vascular grafts (TEVGs) produced via melt electrowriting (MEW)	17
Development of a novel bioartificial cornea using 3D bioprinting based on electrospun micro-nanofibrous decellularized extracellular matrix	16
Laser-guided programmable construction of cell-laden hydrogel microstructures for in vitro drug evaluation	16
Rejuvenation of extensively passaged human chondrocytes to engineer functional articular cartilage	16
Surface slicing and toolpath planning for in-situ bioprinting of skin implants	16
3D bioprinting of stromal cells-laden artificial cornea based on visible light-crosslinkable bioinks forming multilength networks	16
Sacrificial scaffold-assisted direct ink writing of engineered aortic valve prostheses	16
3D-bioprinted, phototunable hydrogel models for studying adventitial fibroblast activation in pulmonary arterial hypertension	16
Recent progress of organ-on-a-chip towards cardiovascular diseases: advanced design, fabrication, and applications	16
Novel 3D-printing bilayer GelMA-based hydrogel containing BP, β-TCP and exosomes for cartilage–bone integrated repair	16
Soft pneumatic actuators for mimicking multi-axial femoropopliteal artery mechanobiology	16
Bone on-a-chip: a 3D dendritic network in a screening platform for osteocyte-targeted drugs	15
Scalable fabrication of renal spheroids and nephron-like tubules by bioprinting and controlled self-assembly of epithelial cells	15
Advancements in gradient bone scaffolds: enhancing bone regeneration in the treatment of various bone disorders	15
Internally crosslinked alginate-based bioinks for the fabrication of in vitro hepatic tissue models	15
Engineering pre-vascularized 3D tissue and rapid vascular integration with host blood vessels via co-cultured spheroids-laden hydrogel	15
BMP-2-immobilized PCL 3D printing scaffold with a leaf-stacked structure as a physically and biologically activated bone graft	15
Enhancement of lacrimal gland cell function by decellularized lacrimal gland derived hydrogel	15
A targeted rheological bioink development guideline and its systematic correlation with printing behavior	15
Neural priming of adipose-derived stem cells by cell-imprinted substrates*	15
Comparative analysis of the residues of granular support bath materials on printed structures in embedded extrusion printing	15
From local to global matrix organization by fibroblasts: a 4D laser-assisted bioprinting approach	15
Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation	15
Growing human-scale scala tympani-like in vitro cell constructs	15
A scalable human iPSC-based neuromuscular disease model on suspended biobased elastomer nanofiber scaffolds	15
Biofabricated nanomaterials in sustainable agriculture: insights, challenges and prospects	15
Steering cell orientation through light-based spatiotemporal modulation of the mechanical environment	15
On-chip fabrication and in-flow 3D-printing of microgel constructs: from chip to scaffold materials in one integral process	15
Ionically annealed zwitterionic microgels for bioprinting of cartilaginous constructs	15