OOIR: Observatory of International Research

Papers

(The TQCC of Biofabrication is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-11-01 to 2023-11-01.)

Article	Citations
The bioprinting roadmap	238
Engineering bioinks for 3D bioprinting	103
Precisely defined fiber scaffolds with 40 μm porosity induce elongation driven M2-like polarization of human macrophages	99
Engineering considerations on extrusion-based bioprinting: interactions of material behavior, mechanical forces and cells in the printing needle	84
Combining multi-scale 3D printing technologies to engineer reinforced hydrogel-ceramic interfaces	80
Improving alginate printability for biofabrication: establishment of a universal and homogeneous pre-crosslinking technique	74
3D printed oxidized alginate-gelatin bioink provides guidance for C2C12 muscle precursor cell orientation and differentiation via shear stress during bioprinting	70
Endothelial cells support osteogenesis in an in vitro vascularized bone model developed by 3D bioprinting	70
Nanoclay-based 3D printed scaffolds promote vascular ingrowth ex vivo and generate bone mineral tissue in vitro and in vivo	65
Printability in extrusion bioprinting	59
Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model	47
4D biofabrication of skeletal muscle microtissues	45
3D Printing of large-scale and highly porous biodegradable tissue engineering scaffolds from poly(trimethylene-carbonate) using two-photon-polymerization	45
Modeling the printability of photocuring and strength adjustable hydrogel bioink during projection-based 3D bioprinting	42
Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications	42
A novel tumor-immune microenvironment (TIME)-on-Chip mimics three dimensional neutrophil-tumor dynamics and neutrophil extracellular traps (NETs)-mediated collective tumor invasion	42
Biofabrication of endothelial cell, dermal fibroblast, and multilayered keratinocyte layers for skin tissue engineering	41
Recent advances in 3D bioprinting of musculoskeletal tissues	40
GelMA/bioactive silica nanocomposite bioinks for stem cell osteogenic differentiation	39
3D cell-printing of tendon-bone interface using tissue-derived extracellular matrix bioinks for chronic rotator cuff repair	39
Sound-induced morphogenesis of multicellular systems for rapid orchestration of vascular networks	38
Dual drug delivery system based on pH-sensitive silk fibroin/alginate nanoparticles entrapped in PNIPAM hydrogel for treating severe infected burn wound	38
Multimaterial bioprinting and combination of processing techniques towards the fabrication of biomimetic tissues and organs	37
3D printed titanium scaffolds with homogeneous diamond-like structures mimicking that of the osteocyte microenvironment and its bone regeneration study	37
Dynamic peptide-folding mediated biofunctionalization and modulation of hydrogels for 4D bioprinting	37

Self-crosslinking hyaluronic acid–carboxymethylcellulose hydrogel enhances multilayered 3D-printed construct shape integrity and mechanical stability for soft tissue engineering	37
Using chaotic advection for facile high-throughput fabrication of ordered multilayer micro- and nanostructures: continuous chaotic printing	36
Dynamic hyaluronic acid hydrogel with covalent linked gelatin as an anti-oxidative bioink for cartilage tissue engineering	35
4D Biofabrication of fibrous artificial nerve graft for neuron regeneration	35
Combinations of photoinitiator and UV absorber for cell-based digital light processing (DLP) bioprinting	35
High throughput direct 3D bioprinting in multiwell plates	35
Recent advancements in the bioprinting of vascular grafts	34
Droplet-based microfluidics in biomedical applications	33
Multi-material digital light processing bioprinting of hydrogel-based microfluidic chips	32
On-chip high-definition bioprinting of microvascular structures	32
Bio-3D printing iPSC-derived human chondrocytes for articular cartilage regeneration	30
Bioprinting of an osteocyte network for biomimetic mineralization	30
Aspiration-assisted bioprinting of co-cultured osteogenic spheroids for bone tissue engineering	30
Green electrospinning for biomaterials and biofabrication	29
4D bioprintable self-healing hydrogel with shape memory and cryopreserving properties	29
Double network laminarin-boronic/alginate dynamic bioink for 3D bioprinting cell-laden constructs	29
A targeted rheological bioink development guideline and its systematic correlation with printing behavior	29
Alginate–gelatin–Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models	29
Fabrication of MSC-laden composites of hyaluronic acid hydrogels reinforced with MEW scaffolds for cartilage repair	28
Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin	28
Vascularized adipocyte organoid model using isolated human microvessel fragments	27
Magnetic molding of tumor spheroids: emerging model for cancer screening	27
Bio-instructive hydrogel expands the paracrine potency of mesenchymal stem cells	27
Combining electrospinning with hot drawing process to fabricate high performance poly (L-lactic acid) nanofiber yarns for advanced nanostructured bio-textiles	27
Recapitulating monocyte extravasation to the synovium in an organotypic microfluidic model of the articular joint	27
A biofabrication method to align cells within bioprinted photocrosslinkable and cell-degradable hydrogel constructs via embedded fibers	26
Enabling peristalsis of human colon tumor organoids on microfluidic chips	25
3D bioprinting of molecularly engineered PEG-based hydrogels utilizing gelatin fragments	25
Improved accuracy and precision of bioprinting through progressive cavity pump-controlled extrusion	23
Decellularized kidney extracellular matrix bioinks recapitulate renal 3D microenvironment in vitro	23
Cartilage tissue engineering by extrusion bioprinting utilizing porous hyaluronic acid microgel bioinks	23
A digital light processing 3D printed magnetic bioreactor system using silk magnetic bioink	23
High throughput microfluidic system with multiple oxygen levels for the study of hypoxia in tumor spheroids	22
Towards engineering heart tissues from bioprinted cardiac spheroids	22
Bioactive Sr²⁺/Fe³⁺ co-substituted hydroxyapatite in cryogenically 3D printed porous scaffolds for bone tissue engineering	22
Biomimetic and mechanically supportive 3D printed scaffolds for cartilage and osteochondral tissue engineering using photopolymers and digital light processing	21
Enhanced vascularization and de novo tissue formation in hydrogels made of engineered RGD-tagged spider silk proteins in the arteriovenous loop model	21
Fabrication of microvascular constructs using high resolution electrohydrodynamic inkjet printing	21
A core–shell multi-drug platform to improve gastrointestinal tract microbial health using 3D printing	20
Tunable metacrylated hyaluronic acid-based hybrid bioinks for stereolithography 3D bioprinting	20
Bioengineered in vitro 3D model of myotonic dystrophy type 1 human skeletal muscle	20
BoneMA—synthesis and characterization of a methacrylated bone-derived hydrogel for bioprinting of in-vitro vascularized tissue constructs	20
A simplified yet enhanced and versatile microfluidic platform for cyclic cell stretching on an elastic polymer	19
Simultaneous 2D and 3D cell culture array for multicellular geometry, drug discovery and tumor microenvironment reconstruction	19
Bioink with cartilage-derived extracellular matrix microfibers enables spatial control of vascular capillary formation in bioprinted constructs	18
An injectable bioink with rapid prototyping in the air and in-situ mild polymerization for 3D bioprinting	18
Angiogenic factors secreted from human ASC spheroids entrapped in an alginate-based hierarchical structure via combined 3D printing/electrospinning system	18
Aspiration-assisted freeform bioprinting of mesenchymal stem cell spheroids within alginate microgels	18
Coaxial printing of double-layered and free-standing blood vessel analogues without ultraviolet illumination for high-volume vascularised tissue	18
Expanding sacrificially printed microfluidic channel-embedded paper devices for construction of volumetric tissue models in vitro	18

Mimicking tumor microenvironment by 3D bioprinting: 3D cancer modeling	18
Micro-electrode channel guide (µECG) technology: an online method for continuous electrical recording in a human beating heart-on-chip	17
Next generation human brain models: engineered flat brain organoids featuring gyrification	17
Neural stem cell delivery using brain-derived tissue-specific bioink for recovering from traumatic brain injury	17
Biofabrication of vasculature in microphysiological models of bone	17
Architected fibrous scaffolds for engineering anisotropic tissues	17
Bioprinted microvasculature: progressing from structure to function	17
Functional evaluation of prevascularization in one-stage versus two-stage tissue engineering approach of human bio-artificial muscle	17
3D printing of sacrificial thioester elastomers using digital light processing for templating 3D organoid structures in soft biomatrices	17
Direct extrusion of individually encapsulated endothelial and smooth muscle cells mimicking blood vessel structures and vascular native cell alignment	16
Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications	16
3D bioprinted, vascularized neuroblastoma tumor environment in fluidic chip devices for precision medicine drug testing	16
FRESH 3D bioprinting a contractile heart tube using human stem cell-derived cardiomyocytes	16
Biofabrication of muscle fibers enhanced with plant viral nanoparticles using surface chaotic flows	16
Scalable fabrication of renal spheroids and nephron-like tubules by bioprinting and controlled self-assembly of epithelial cells	16
Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform	16
Development of a novel dual reproductive organ on a chip: recapitulating bidirectional endocrine crosstalk between the uterine endometrium and the ovary	16
Engineered assistive materials for 3D bioprinting: support baths and sacrificial inks	16
Polydopamine-coated polycaprolactone/carbon nanotube fibrous scaffolds loaded with brain-derived neurotrophic factor for peripheral nerve regeneration	16
Rapid multilayer microfabrication for modeling organotropic metastasis in breast cancer	16
Stem cell spheroid engineering with osteoinductive and ROS scavenging nanofibers for bone regeneration	16
In vivo organized neovascularization induced by 3D bioprinted endothelial-derived extracellular vesicles	16
1D and 2D error assessment and correction for extrusion-based bioprinting using process sensing and control strategies	16
Core–shell bioprinting as a strategy to apply differentiation factors in a spatially defined manner inside osteochondral tissue substitutes	15
A perfusable vascularized full-thickness skin model for potential topical and systemic applications	15
An engineered neurovascular unit for modeling neuroinflammation	15
Study of the process-induced cell damage in forced extrusion bioprinting	15
A microphysiological system combining electrospun fibers and electrical stimulation for the maturation of highly anisotropic cardiac tissue	15
Printability and bio-functionality of a shear thinning methacrylated xanthan–gelatin composite bioink	15
Valve-based consecutive bioprinting method for multimaterial tissue-like constructs with controllable interfaces	15