Stem Cell Research & Therapy

Article	Citations
CAR T cells in solid tumors: challenges and opportunities	365
Advances in mesenchymal stem cell exosomes: a review	175
RETRACTED ARTICLE: Mesenchymal stem/stromal cells as a valuable source for the treatment of immune-mediated disorders	172
Mesenchymal stem cells: amazing remedies for bone and cartilage defects	166
Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review	159
The application of mesenchymal stromal cells (MSCs) and their derivative exosome in skin wound healing: a comprehensive review	153
Overview of current adipose-derived stem cell (ADSCs) processing involved in therapeutic advancements: flow chart and regulation updates before and after COVID-19	142
Mesenchymal stem cells derived from perinatal tissues for treatment of critically ill COVID-19-induced ARDS patients: a case series	140
What is the impact of human umbilical cord mesenchymal stem cell transplantation on clinical treatment?	138
Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis	134
Comprehensive proteomic analysis of exosomes derived from human bone marrow, adipose tissue, and umbilical cord mesenchymal stem cells	131
Hypoxic hUCMSC-derived extracellular vesicles attenuate allergic airway inflammation and airway remodeling in chronic asthma mice	126
Mesenchymal stem cell-derived exosomes: therapeutic opportunities and challenges for spinal cord injury	121
Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives	116
Bone marrow mesenchymal stem cell-derived exosomes promote rotator cuff tendon-bone healing by promoting angiogenesis and regulating M1 macrophages in rats	113
MiR-375 reduces the stemness of gastric cancer cells through triggering ferroptosis	112
Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials	105
Mesenchymal stem cells-derived exosomes for drug delivery	104
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages	102
A novel therapeutic approach for inflammatory bowel disease by exosomes derived from human umbilical cord mesenchymal stem cells to repair intestinal barrier via TSG-6	98
The safety of MSC therapy over the past 15 years: a meta-analysis	97
Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor inhibition	96
Mesenchymal stem/stromal cell-derived exosomes in regenerative medicine and cancer; overview of development, challenges, and opportunities	92
Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration	89
Nebulized exosomes derived from allogenic adipose tissue mesenchymal stromal cells in patients with severe COVID-19: a pilot study	88

hucMSC-derived exosomes attenuate colitis by regulating macrophage pyroptosis via the miR-378a-5p/NLRP3 axis	87
Human acellular amniotic membrane incorporating exosomes from adipose-derived mesenchymal stem cells promotes diabetic wound healing	84
A deep insight into CRISPR/Cas9 application in CAR-T cell-based tumor immunotherapies	84
Exosomes from adipose-derived stem cells regulate M1/M2 macrophage phenotypic polarization to promote bone healing via miR-451a/MIF	83
RETRACTED ARTICLE: Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction	81
Mitochondria and metabolic transitions in cardiomyocytes: lessons from development for stem cell-derived cardiomyocytes	80
Human umbilical cord-derived mesenchymal stem/stromal cells: a promising candidate for the development of advanced therapy medicinal products	78
The role and mechanism of mitochondrial functions and energy metabolism in the function regulation of the mesenchymal stem cells	78
Mesenchymal stromal cell-based therapy for cartilage regeneration in knee osteoarthritis	77
Differences and similarities between cancer and somatic stem cells: therapeutic implications	75
Novel CAR T therapy is a ray of hope in the treatment of seriously ill AML patients	75
Signaling pathways governing breast cancer stem cells behavior	75
Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis	74
Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing	73
Mesenchymal stem cells and their microenvironment	73
Biomaterial-supported MSC transplantation enhances cell–cell communication for spinal cord injury	70
Umbilical mesenchymal stem cell-derived exosomes facilitate spinal cord functional recovery through the miR-199a-3p/145-5p-mediated NGF/TrkA signaling pathway in rats	70
Local delivery of USC-derived exosomes harboring ANGPTL3 enhances spinal cord functional recovery after injury by promoting angiogenesis	68
Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly promoted cutaneous wound healing and regeneration	66
Hollow-fiber bioreactor production of extracellular vesicles from human bone marrow mesenchymal stromal cells yields nanovesicles that mirrors the immuno-modulatory antigenic signature of the producer	66
A systematic summary of survival and death signalling during the life of hair follicle stem cells	64
Exosomal hsa_circ_0006859 is a potential biomarker for postmenopausal osteoporosis and enhances adipogenic versus osteogenic differentiation in human bone marrow mesenchymal stem cells by sponging miR	63
miR-126-3p containing exosomes derived from human umbilical cord mesenchymal stem cells promote angiogenesis and attenuate ovarian granulosa cell apoptosis in a preclinical rat model of premature ovar	61
Mesenchymal stem cell-secreted prostaglandin E2 ameliorates acute liver failure via attenuation of cell death and regulation of macrophage polarization	60
The therapeutic potential of stem cell-derived exosomes in the ulcerative colitis and colorectal cancer	59
Cell therapy in patients with COVID-19 using Wharton’s jelly mesenchymal stem cells: a phase 1 clinical trial	59
Organoids: a systematic review of ethical issues	59
Exosomes secreted by FNDC5-BMMSCs protect myocardial infarction by anti-inflammation and macrophage polarization via NF-κB signaling pathway and Nrf2/HO-1 axis	58
Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway	57
Transplantation of human umbilical cord mesenchymal stem cells to treat premature ovarian failure	57
Biomimetic nerve guidance conduit containing engineered exosomes of adipose-derived stem cells promotes peripheral nerve regeneration	57
Applications, challenges and prospects of mesenchymal stem cell exosomes in regenerative medicine	56
Stem cell-based therapy for ameliorating intrauterine adhesion and endometrium injury	56
Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage polarization	56
Research progress of the application of mesenchymal stem cells in chronic inflammatory systemic diseases	56
Stem cell therapy for Crohn’s disease: systematic review and meta-analysis of preclinical and clinical studies	56
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles ameliorate airway inflammation in a rat model of chronic obstructive pulmonary disease (COPD)	55
BMSC-derived exosomes promote tendon-bone healing after anterior cruciate ligament reconstruction by regulating M1/M2 macrophage polarization in rats	55
Exosomes derived from miR-26a-modified MSCs promote axonal regeneration via the PTEN/AKT/mTOR pathway following spinal cord injury	54
Exosomes derived from human placental mesenchymal stem cells enhanced the recovery of spinal cord injury by activating endogenous neurogenesis	54
Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects	54
Characteristics of the cancer stem cell niche and therapeutic strategies	54
Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p	54
Exosomal microRNA-22-3p alleviates cerebral ischemic injury by modulating KDM6B/BMP2/BMF axis	54
Cardiac organoid — a promising perspective of preclinical model	53
Concentrated exosomes from menstrual blood-derived stromal cells improves ovarian activity in a rat model of premature ovarian insufficiency	53
Mesenchymal stem cell-derived exosome-educated macrophages alleviate systemic lupus erythematosus by promoting efferocytosis and recruitment of IL-17+ regulatory T cell	53
MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization	52
Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects	52
Induced pluripotent stem cell-derived mesenchymal stem cells deliver exogenous miR-105-5p via small extracellular vesicles to rejuvenate senescent nucleus pulposus cells and attenuate intervertebral d	51

Mesenchymal stem cell-derived exosomes protect against liver fibrosis via delivering miR-148a to target KLF6/STAT3 pathway in macrophages	51
Exosomal lncRNA TUG1 derived from human urine-derived stem cells attenuates renal ischemia/reperfusion injury by interacting with SRSF1 to regulate ASCL4-mediated ferroptosis	50
Labial gland-derived mesenchymal stem cells and their exosomes ameliorate murine Sjögren's syndrome by modulating the balance of Treg and Th17 cells	50
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated autophagy	49
Characterization of stem cell landscape and identification of stemness-relevant prognostic gene signature to aid immunotherapy in colorectal cancer	49
Drug resistance in cancer therapy: the Pandora's Box of cancer stem cells	48
Human mesenchymal stem cell treatment of premature ovarian failure: new challenges and opportunities	48
Low level laser therapy promotes bone regeneration by coupling angiogenesis and osteogenesis	47
Chitosan hydrogel-loaded MSC-derived extracellular vesicles promote skin rejuvenation by ameliorating the senescence of dermal fibroblasts	47
microRNA-27b shuttled by mesenchymal stem cell-derived exosomes prevents sepsis by targeting JMJD3 and downregulating NF-κB signaling pathway	47
EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/β-catenin signaling	47
CAR-T cell therapy in T-cell malignancies: Is success a low-hanging fruit?	46
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage	46
Immunomodulatory effects of mesenchymal stem cells in peripheral nerve injury	46
Reprogrammed mesenchymal stem cells derived from iPSCs promote bone repair in steroid-associated osteonecrosis of the femoral head	45
Applications of the amniotic membrane in tissue engineering and regeneration: the hundred-year challenge	45
Exosomes from adipose tissue-derived mesenchymal stem cells ameliorate histone-induced acute lung injury by activating the PI3K/Akt pathway in endothelial cells	45
Lung organoids, useful tools for investigating epithelial repair after lung injury	45
Melatonin enhances osteogenic differentiation of dental pulp mesenchymal stem cells by regulating MAPK pathways and promotes the efficiency of bone regeneration in calvarial bone defects	45
Overcoming bioprocess bottlenecks in the large-scale expansion of high-quality hiPSC aggregates in vertical-wheel stirred suspension bioreactors	45
Exosomes derived from adipose-derived stem cells overexpressing glyoxalase-1 protect endothelial cells and enhance angiogenesis in type 2 diabetic mice with limb ischemia	44
The potential use of mesenchymal stem cells and their exosomes in Parkinson’s disease treatment	44
Melatonin promotes bone marrow mesenchymal stem cell osteogenic differentiation and prevents osteoporosis development through modulating circ_0003865 that sponges miR-3653-3p	44
Efficacy of stem cells therapy for Crohn’s fistula: a meta-analysis and systematic review	44
Mesenchymal stem cell transplantation after acute myocardial infarction: a meta-analysis of clinical trials	44
Human menstrual blood-derived stem cells mitigate bleomycin-induced pulmonary fibrosis through anti-apoptosis and anti-inflammatory effects	44
Detection of viral RNA fragments in human iPSC cardiomyocytes following treatment with extracellular vesicles from SARS-CoV-2 coding sequence overexpressing lung epithelial cells	43
Emerging role of mesenchymal stromal cells (MSCs)-derived exosome in neurodegeneration-associated conditions: a groundbreaking cell-free approach	43
Human umbilical cord mesenchymal stem cell-derived exosomal miR-27b attenuates subretinal fibrosis via suppressing epithelial–mesenchymal transition by targeting HOXC6	43
Intravitreal autologous mesenchymal stem cell transplantation: a non-randomized phase I clinical trial in patients with retinitis pigmentosa	43
Exosomes derived from three-dimensional cultured human umbilical cord mesenchymal stem cells ameliorate pulmonary fibrosis in a mouse silicosis model	43
Fetal liver hematopoiesis: from development to delivery	43
Natural killer cell therapy for hematologic malignancies: successes, challenges, and the future	43
Transplantation of photobiomodulation-preconditioned diabetic stem cells accelerates ischemic wound healing in diabetic rats	43
Human umbilical cord mesenchymal stem cells ameliorate erectile dysfunction in rats with diabetes mellitus through the attenuation of ferroptosis	43
SiRNA in MSC-derived exosomes silences CTGF gene for locomotor recovery in spinal cord injury rats	43
Exosome from indoleamine 2,3-dioxygenase-overexpressing bone marrow mesenchymal stem cells accelerates repair process of ischemia/reperfusion-induced acute kidney injury by regulating macrophages pola	42
The tRNA-derived fragment 5026a inhibits the proliferation of gastric cancer cells by regulating the PTEN/PI3K/AKT signaling pathway	42
Adipose-derived mesenchymal stromal cell-derived exosomes promote tendon healing by activating both SMAD1/5/9 and SMAD2/3	42
Unresponsive thin endometrium caused by Asherman syndrome treated with umbilical cord mesenchymal stem cells on collagen scaffolds: a pilot study	42
Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model	42
Uncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic, and degenerative intervertebral discs: a proteomic analysis	42
Exosomes from miRNA-378-modified adipose-derived stem cells prevent glucocorticoid-induced osteonecrosis of the femoral head by enhancing angiogenesis and osteogenesis via targeting miR-378 negatively	42
Shining the light on clinical application of mesenchymal stem cell therapy in autoimmune diseases	42
Application of stem cells in the repair of intervertebral disc degeneration	41
Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo	41
IFN-γ enhances the efficacy of mesenchymal stromal cell-derived exosomes via miR-21 in myocardial infarction rats	41
Mesenchymal stem cell therapy ameliorates metabolic dysfunction and restores fertility in a PCOS mouse model through interleukin-10	41
Endometrial stem/progenitor cells and their roles in immunity, clinical application, and endometriosis	41
Human umbilical cord-derived mesenchymal stem cells improve the function of liver in rats with acute-on-chronic liver failure via downregulating Notch and Stat1/Stat3 signaling	41
MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy	40
Subconjunctival injection of mesenchymal stem cells for corneal failure due to limbal stem cell deficiency: state of the art	40
Constructing a cell microenvironment with biomaterial scaffolds for stem cell therapy	40
Exosomal miR-17-5p from adipose-derived mesenchymal stem cells inhibits abdominal aortic aneurysm by suppressing TXNIP-NLRP3 inflammasome	40
Tongxinluo-pretreated mesenchymal stem cells facilitate cardiac repair via exosomal transfer of miR-146a-5p targeting IRAK1/NF-κB p65 pathway	40
Systemic therapy of MSCs in bone regeneration: a systematic review and meta-analysis	40
Mapping current research and identifying hotspots on mesenchymal stem cells in cardiovascular disease	40
Circular RNA TTC3 regulates cerebral ischemia-reperfusion injury and neural stem cells by miR-372-3p/TLR4 axis in cerebral infarction	40
microRNA-186 in extracellular vesicles from bone marrow mesenchymal stem cells alleviates idiopathic pulmonary fibrosis via interaction with SOX4 and DKK1	40
Resolvin E1 accelerates pulp repair by regulating inflammation and stimulating dentin regeneration in dental pulp stem cells	39
Human adipose-derived stem cells enriched with VEGF-modified mRNA promote angiogenesis and long-term graft survival in a fat graft transplantation model	39
Cell-based therapy in thin endometrium and Asherman syndrome	39
si-SNHG5-FOXF2 inhibits TGF-β1-induced fibrosis in human primary endometrial stromal cells by the Wnt/β-catenin signalling pathway	39
MSC-NTF (NurOwn®) exosomes: a novel therapeutic modality in the mouse LPS-induced ARDS model	39
Immune evader cancer stem cells direct the perspective approaches to cancer immunotherapy	39
PINK1 contained in huMSC-derived exosomes prevents cardiomyocyte mitochondrial calcium overload in sepsis via recovery of mitochondrial Ca2+ efflux	38
CAR-engineered NK cells; a promising therapeutic option for treatment of hematological malignancies	38
Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells	38
Extracellular vesicle mimics made from iPS cell-derived mesenchymal stem cells improve the treatment of metastatic prostate cancer	38
Systematic review: Advances of fat tissue engineering as bioactive scaffold, bioactive material, and source for adipose-derived mesenchymal stem cells in wound and scar treatment	38
Chronic obstructive pulmonary disease and asthma: mesenchymal stem cells and their extracellular vesicles as potential therapeutic tools	38
Chronic myeloid leukemia stem cells: targeting therapeutic implications	38
Recent advances on small molecules in osteogenic differentiation of stem cells and the underlying signaling pathways	38
Surfing the clinical trials of mesenchymal stem cell therapy in ischemic cardiomyopathy	38
Treatment of knee osteoarthritis with intra-articular injection of allogeneic adipose-derived stem cells (ADSCs) ELIXCYTE®: a phase I/II, randomized, active-control, single-blind, multiple-center clin	37
Mesenchymal stromal/stem cells and their exosomes for restoration of spermatogenesis in non-obstructive azoospermia: a systemic review	37
Current status of clinical trials assessing mesenchymal stem cell therapy for graft versus host disease: a systematic review	37
Human umbilical cord-derived mesenchymal stem cells not only ameliorate blood glucose but also protect vascular endothelium from diabetic damage through a paracrine mechanism mediated by MAPK/ERK sign	37
Safety and long-term improvement of mesenchymal stromal cell infusion in critically COVID-19 patients: a randomized clinical trial	37
Human umbilical cord mesenchymal stem cells restore the ovarian metabolome and rescue premature ovarian insufficiency in mice	37

Mesenchymal stem cell transplantation in newly diagnosed type-1 diabetes patients: a phase I/II randomized placebo-controlled clinical trial	36
Mesenchymal stem cell homing to improve therapeutic efficacy in liver disease	36
Involvement of the long noncoding RNA H19 in osteogenic differentiation and bone regeneration	36
Combining cell therapy with human autologous Schwann cell and bone marrow-derived mesenchymal stem cell in patients with subacute complete spinal cord injury: safety considerations and possible outcom	36
Optimising NK cell metabolism to increase the efficacy of cancer immunotherapy	36
Application of adipose-derived stem cells in photoaging: basic science and literature review	36
Cytokine-induced memory-like natural killer cells for cancer immunotherapy	35
The assessment of mesenchymal stem cells therapy in acute on chronic liver failure and chronic liver disease: a systematic review and meta-analysis of randomized controlled clinical trials	35
Secreted factors from dental pulp stem cells improve Sjögren’s syndrome via regulatory T cell-mediated immunosuppression	35
Mesenchymal stem cells and extracellular vesicles in therapy against kidney diseases	35
Exosomes from mmu_circ_0001052-modified adipose-derived stem cells promote angiogenesis of DFU via miR-106a-5p and FGF4/p38MAPK pathway	35
Stem cell-derived and circulating exosomal microRNAs as new potential tools for diabetic nephropathy management	35
Improvement of sensory neuron growth and survival via negatively regulating PTEN by miR-21-5p-contained small extracellular vesicles from skin precursor-derived Schwann cells	35
The cross talk between gastric cancer stem cells and the immune microenvironment: a tumor-promoting factor	35
Human epidermal growth factor receptor 2 (HER2)-specific chimeric antigen receptor (CAR) for tumor immunotherapy; recent progress	34
Comprehensive proteomic analysis of exosome mimetic vesicles and exosomes derived from human umbilical cord mesenchymal stem cells	34
PINK1 deficiency impairs osteoblast differentiation through aberrant mitochondrial homeostasis	34
ADSCs-derived exosomes ameliorate hepatic fibrosis by suppressing stellate cell activation and remodeling hepatocellular glutamine synthetase-mediated glutamine and ammonia homeostasis	34
Small extracellular vesicles from menstrual blood-derived mesenchymal stem cells (MenSCs) as a novel therapeutic impetus in regenerative medicine	34
Impact of 3D cell culture on bone regeneration potential of mesenchymal stromal cells	34
SOX9 inactivation affects the proliferation and differentiation of human lung organoids	34
Inflammatory cytokines-stimulated human muscle stem cells ameliorate ulcerative colitis via the IDO-TSG6 axis	34
Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles	34
Important role of the SDF-1/CXCR4 axis in the homing of systemically transplanted human amnion-derived mesenchymal stem cells (hAD-MSCs) to ovaries in rats with chemotherapy-induced premature ovarian	33
Systemic proteomics and miRNA profile analysis of exosomes derived from human pluripotent stem cells	33
Human mesenchymal stem cell therapy promotes retinal ganglion cell survival and target reconnection after optic nerve crush in adult rats	33
Conditioned medium from induced pluripotent stem cell-derived mesenchymal stem cells accelerates cutaneous wound healing through enhanced angiogenesis	33
Mesenchymal stromal cell therapy for COVID-19-induced ARDS patients: a successful phase 1, control-placebo group, clinical trial	33
Comparative analysis of mouse bone marrow and adipose tissue mesenchymal stem cells for critical limb ischemia cell therapy	33
MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesis	33
Bone marrow derived-mesenchymal stem cell improves diabetes-associated fatty liver via mitochondria transformation in mice	33
Engineering strategies for customizing extracellular vesicle uptake in a therapeutic context	33
Engineered adipose-derived stem cells with IGF-1-modified mRNA ameliorates osteoarthritis development	33
Application of magnetic nanoparticles in cell therapy	33
STAT3 activation by catalpol promotes osteogenesis-angiogenesis coupling, thus accelerating osteoporotic bone repair	33
The potential therapy with dental tissue-derived mesenchymal stem cells in Parkinson’s disease	32
Mesenchymal stem cells combined with autocrosslinked hyaluronic acid improve mouse ovarian function by activating the PI3K-AKT pathway in a paracrine manner	32
Regulatory T cell induction by mesenchymal stem cells depends on the expression of TNFR2 by T cells	32
Human amniotic mesenchymal stem cells to promote/suppress cancer: two sides of the same coin	32
Hypoxia preconditioned bone marrow-derived mesenchymal stromal/stem cells enhance myoblast fusion and skeletal muscle regeneration	32
The adipose-derived mesenchymal stem cell secretome promotes hepatic regeneration in miniature pigs after liver ischaemia-reperfusion combined with partial resection	32
CD146 controls the quality of clinical grade mesenchymal stem cells from human dental pulp	32
The impact of Zn-doped synthetic polymer materials on bone regeneration: a systematic review	32
Neural stem cells derived from primitive mesenchymal stem cells reversed disease symptoms and promoted neurogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis	31
Stem cells differentiation into insulin-producing cells (IPCs): recent advances and current challenges	31
Characterisation of mesenchymal stromal cells in clinical trial reports: analysis of published descriptors	31
PDGF-BB and IL-4 co-overexpression is a potential strategy to enhance mesenchymal stem cell-based bone regeneration	31
Momordica charantia polysaccharides modulate the differentiation of neural stem cells via SIRT1/Β-catenin axis in cerebral ischemia/reperfusion	31
3D-printed nerve guidance conduits multi-functionalized with canine multipotent mesenchymal stromal cells promote neuroregeneration after sciatic nerve injury in rats	31
Synergistic regenerative therapy of thin endometrium by human placenta-derived mesenchymal stem cells encapsulated within hyaluronic acid hydrogels	31
The effects and potential applications of concentrated growth factor in dentin–pulp complex regeneration	31
Differentiation of human induced pluripotent stem cells into erythroid cells	31
Circular RNA SIPA1L1 regulates osteoblastic differentiation of stem cells from apical papilla via miR-204-5p/ALPL pathway	31
Human amniotic mesenchymal stem cells-derived IGFBP-3, DKK-3, and DKK-1 attenuate liver fibrosis through inhibiting hepatic stellate cell activation by blocking Wnt/β-catenin signaling pathway in mice	31
Endothelial progenitor cells promote osteogenic differentiation in co-cultured with mesenchymal stem cells via the MAPK-dependent pathway	31
Hypoxic mesenchymal stem cells ameliorate acute kidney ischemia-reperfusion injury via enhancing renal tubular autophagy	31
Inhibition of miR-199a-5p rejuvenates aged mesenchymal stem cells derived from patients with idiopathic pulmonary fibrosis and improves their therapeutic efficacy in experimental pulmonary fibrosis	31
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients	31
Comparison of chondrogenesis-related biological behaviors between human urine-derived stem cells and human bone marrow mesenchymal stem cells from the same individual	31
Spotlight on therapeutic efficiency of mesenchymal stem cells in viral infections with a focus on COVID-19	31
Single-cell RNA sequencing of equine mesenchymal stromal cells from primary donor-matched tissue sources reveals functional heterogeneity in immune modulation and cell motility	31
Adipose-derived mesenchymal stem cells attenuate dialysis-induced peritoneal fibrosis by modulating macrophage polarization via interleukin-6	31
Efficacy and safety of umbilical cord-derived mesenchymal stem cells in Chinese adults with type 2 diabetes: a single-center, double-blinded, randomized, placebo-controlled phase II trial	31
Human umbilical cord mesenchymal stromal cell-derived exosomes protect against MCD-induced NASH in a mouse model	30
Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2	30
Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression	30
Stem/progenitor cell in kidney: characteristics, homing, coordination, and maintenance	30
Mesenchymal stem cell-based therapy and exosomes in COVID-19: current trends and prospects	30
The therapeutic efficacy of mesenchymal stromal cells on experimental colitis was improved by the IFN-γ and poly(I:C) priming through promoting the expression of indoleamine 2,3-dioxygenase	30
Hurdles to breakthrough in CAR T cell therapy of solid tumors	30
TNFα and IFNγ rapidly activate PI3K-AKT signaling to drive glycolysis that confers mesenchymal stem cells enhanced anti-inflammatory property	30
Preclinical efficacy of stem cell therapy for skin flap: a systematic review and meta-analysis	30
Prevention of chemotherapy-induced premature ovarian insufficiency in mice by scaffold-based local delivery of human embryonic stem cell-derived mesenchymal progenitor cells	30
Stem cells for treatment of liver fibrosis/cirrhosis: clinical progress and therapeutic potential	30
Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process	30
Lyophilized powder of mesenchymal stem cell supernatant attenuates acute lung injury through the IL-6–p-STAT3–p63–JAG2 pathway	30
Advancements in stem cell-derived hepatocyte-like cell models for hepatotoxicity testing	30
Extracellular vesicles from hair follicle-derived mesenchymal stromal cells: isolation, characterization and therapeutic potential for chronic wound healing	30
Characterization of stable hypoxia-preconditioned dental pulp stem cells compared with mobilized dental pulp stem cells for application for pulp regenerative therapy	30
Bone marrow-derived mesenchymal stem/stromal cells in patients with acute myeloid leukemia reveal transcriptome alterations and deficiency in cellular vitality	30
Regenerative capacity of the corneal transition zone for endothelial cell therapy	30
Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization	30
ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation	29
Safety and efficacy study of allogeneic human menstrual blood stromal cells secretome to treat severe COVID-19 patients: clinical trial phase I & II	29
Exosomes derived from miR-301a-3p-overexpressing adipose-derived mesenchymal stem cells reverse hypoxia-induced erectile dysfunction in rat models	29
Melatonin treatment improves human umbilical cord mesenchymal stem cell therapy in a mouse model of type II diabetes mellitus via the PI3K/AKT signaling pathway	29
Mesenchymal stem cell-derived exosomes as a new therapeutic strategy in the brain tumors	29
Mesenchymal stromal cells (MSCs) and their exosome in acute liver failure (ALF): a comprehensive review	29
Engineered basic fibroblast growth factor-overexpressing human umbilical cord-derived mesenchymal stem cells improve the proliferation and neuronal differentiation of endogenous neural stem cells and	29
DPSCs treated by TGF-β1 regulate angiogenic sprouting of three-dimensionally co-cultured HUVECs and DPSCs through VEGF-Ang-Tie2 signaling	29
hiPSC-derived NSCs effectively promote the functional recovery of acute spinal cord injury in mice	29
BMSC-derived extracellular vesicles intervened the pathogenic changes of scleroderma in mice through miRNAs	29
Application of mesenchymal stem cell sheet to treatment of ischemic heart disease	29
Adrenomedullin 2 improves bone regeneration in type 1 diabetic rats by restoring imbalanced macrophage polarization and impaired osteogenesis	28
METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells	28