Bioanalysis

Papers
(The TQCC of Bioanalysis is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Meet the Editorial Board – An Interview with Min Meng and Transitions from Small Regional Labs to Global CRO46
Biomonitoring of Arsenic, Lead, Manganese and Mercury in Hair from a Presumably Exposed Uruguayan Child Population34
Volumetric Absorptive Microsampling as An Effective Microsampling Technique for LC–MS/MS Bioanalysis of Biomarkers in Drug Discovery30
Patient centric blood sampling and analysis for diagnostics and laboratory medicine28
MS-DIAL pre-processing for mining schistosomiasis metabolites in urine samples from the Okavango Delta of Botswana from a GC-MS dataset26
Adopting ambient ionization mass spectrometry into bioanalytical laboratories23
The complexities of oligonucleotide therapeutics: analytical challenges and opportunities within early drug discovery22
Bioanalysis by LC-MS/MS and Preclinical Pharmacokinetic Interaction Study of Ribociclib and Oleanolic Acid18
A fully automated novel solid-phase extraction method for siRNA drug extraction and quantitation across multiple tissues using LC-MS16
A validated UHPLC-MS/MS method for determination of BPI-43487 and its metabolite BPI-43739 in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumors16
Peripheral blood mononuclear cells isolation from mouse and rabbit blood to quantify active nucleotide and define brincidofovir dose for smallpox16
Signal-to-noise Ratio to Assess Magnitude, Kinetics and Impact on Pharmacokinetics of the Immune Response to an Adalimumab Biosimilar16
Biomarker Context-Of-Use: How Organizational Design Can Impact the Implementation of the Appropriate Biomarker Assay Strategy15
Patient-centric clinical trials: collaboration and innovation in bioanalytical and clinical operations15
2025 White Paper on Recent Issues in Bioanalysis: Biomarkers Calibrators & Stability; Evaluation of NULISA; Neurofilament & Autoantibody Biomarker Assays; Removing IgM Interference; ELISpot &a15
Uncovering the Green Frontier: Harnessing Deep Eutectic Solvents for Sustainable Bioanalysis15
Mitigating ADA matrix interferences: semiquantitative double immunoprecipitation for anti-bevacizumab antibody in plasma14
Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique14
Strategy and Validation of a Nonclinical Generic Plug-and-Play Antidrug Antibody Method for Human Monoclonal Antibody Biotherapeutics14
Refined ADA testing strategy to overcome sRANKL interference in denosumab/FKS518 immunogenicity assessment13
HPPA as assay substrate for improved capturing of sample variability during cut point analyses in immunogenicity testing12
A clever evaluation of the antidiabetic medications linagliptin and empagliflozin in bulk and spiked urine samples12
Recent advances in gold nanoparticle-based colorimetric aptasensors for chemical and biological analyses12
Whole blood stability in bioanalytical method validation: updated recommendations from the European Bioanalysis Forum12
Selective IgM digestion improves anti-AAV IgG detection in the immune complex assay format12
Determination of carbamazepine in fingerprints: a feasibility study to evaluate adherence in epilepsy patients11
The investigation of connection between anticoagulant therapy and vitamin K homologues in human determined by LC–MS/MS11
Bioanalysis Rising Star Award 2024: interviews with the finalists11
An LC–MS/MS Method for Simultaneous Determination of LB-100 and Its Active Metabolite, Endothall, in Human Plasma11
Accurate quantification of anti-drug antibodies against each unique Fab of a bispecific antibody using an ECL bridging assay11
Diversity and Inclusion in the Bioanalytical Industry: An Interview with Anahita Keyhani11
Bioanalysis of free antisense oligonucleotide payload from antibody–oligonucleotide conjugate by hybridization LC-MS/MS11
Perspectives on a Flexible Strategy for the Management of Nonregulated Bioanalysis10
Development of a fit-for-purpose semi-homogeneous competitive ELISA for total PEG quantitation in a PEGylated molecule10
Special consideration: commentary on the 2025 FDA Bioanalytical Method Validation for Biomarkers10
A comparison of branched DNA and reverse transcriptase quantitative polymerase chain reaction methodologies for quantitation of lipid nanoparticle encapsulated mRNA10
Comparison of Assay Formats Used for the Detection of Pre-Existing Anti-Drug Antibodies Against Monoclonal Antibodies10
A novel LC-MS/MS method for simultaneous estimation of chlordiazepoxide and clidinium in human plasma and its application to pharmacokinetic assessment10
Validation of an LC–MS/MS method for the determination of sotorasib, a KRAS G12C inhibitor, in human plasma10
Transforming drug discovery: the impact of AI and molecular simulation on R&D efficiency10
Ligand-binding assays vs chromatographic platforms for oligonucleotide quantification10
Significant matrix effect in fludarabine quantification in plasma: implications for CAR-T cell therapy monitoring10
Accelerating the discovery of MET inhibitors powered by high-throughput hit identification10
Quantification and pharmacokinetic assessment of SB225002 in mouse: a selective non-peptide CXCR2 antagonist10
Correction10
Inception and Development of a LC–MS/MS Assay for the Multiplexed Quantitation of Nine Human Drug Transporter Biomarkers9
Western Blotting: Evolution of an Old Analytical Method To a New Quantitative Tool for Biomarker Measurements9
Correction9
Highlights of the 13th Japan Bioanalysis Forum Symposium9
Considerations in Designing and Implementing a Bioanalytical Contract Research Organization Key Performance Indicator System9
Method development for the quantification of lead levels in whole blood sampled on Mitra ® with VAMS ® tips by inductively coupled9
Highlights of the 15th Japan Bioanalysis Forum Symposium9
High Ionic Strength Dissociation Assay Reduces Dimeric Target Interference in Immunogenicity Testing8
Augmenting immunogenicity workflows with AI and real-world evidence: failure points, tools, and a closed-loop operational blueprint8
Nucleic acid nanorobot assay for accurate and simplified ASO quantification in mouse plasma8
An interview with Bioanalysis : speaking with the 2025 international reid bioanalytical forum bursary award winners8
Validation of UV–Vis spectrophotometric colorimetric methods for Rifampicin quantification in PBS & biological matrices8
Development and Validation of qPCR Methods for Nucleic Acid Biomarkers as a Drug Development Tool: Points to Consider8
A Sensitive, Robust and High-Throughput Isotope Dilution LC–MS/MS Method for Quantifying Three Folate Forms in Serum8
Novel Isoelectric Target Depletion (ITaD) Protocol Reduces the Need for Specific Reagents for Immunogenicity Testing8
Determination of meropenem in capillary plasma microsamples using LC–MS/MS8
Critical Reagent Inventory Management System and Web Portal Specifically Optimized for Supporting External Clients8
Determination of Amphetamines, Opioids, Cocaine Metabolites and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in Urine Using Biocompatible Solid-Phase Microextraction and Ultra-Performance LC–MS/MS7
Upfront Acid Treatment with Low Final pH: The Development and Testing of a Novel Method to Improve Drug Tolerance in Antidrug Antibody Assays7
Perspective on High-Throughput Bioanalysis to Support In Vitro Assays in Early Drug Discovery7
Beyond contracts: principles for Pharma–CRO collaboration from the European Bioanalysis Forum7
Affinity-maturation engineering via phage display to optimize anti-idiotype antibodies for neutralizing antibody assays7
Internal standard variability: root cause investigation, parallelism for evaluating trackability and practical considerations7
Effect of Chronopharmacology and Food on in Vivo Pharmacokinetic Profile of Mavacamten7
Molecularly Imprinted Electrochemical Biosensor for Thrombin Detection by Comparing Different Monomers7
Development of an LC-MS/MS assay to analyze a lipid-conjugated siRNA by solid phase extraction (SPE) in mouse plasma and tissue using a stable isotope labeled internal standard (SILIS)7
DoE-assisted HPLC method development and validation of enzalutamide and repaglinide in rat plasma7
Determination of aloesone in rat plasma by LC–MS/MS spectrometry and its application in a pharmacokinetic study7
Development and validation of bioanalytical methods to support clinical study of disitamab vedotin6
Comparison of Requirements for Clinical Study of SARS-CoV-2 Antigen Test Kits in China, the USA and Europe6
HPLC Method for Simultaneous Estimation of Paclitaxel and Baicalein: Pharmaceutical and Pharmacokinetic Applications6
Development of LC–MS/MS Method for Cyanoenone Triterpenoid Determination to Support CNS Tissue Distribution Study6
Development and validation of an ELISA method for quantification of the anti-HER3 antibody HMBD-001 in human serum6
Revolutionizing depression diagnosis: earwax analysis for cortisol and beyond6
Greener Bioanalytical Sample Preparation. What is Next?6
Comparison of multiple bioanalytical assay platforms for the quantitation of siRNA therapeutics6
Comparative pharmacokinetic study of Anisodamine Hydrobromide tablets and injection in septic acute lung injury rats6
Role of miRNA-21 in cancer and its application in electrochemical bioanalysis6
Ocular Bioanalysis of Moxifloxacin and Ketorolac Tromethamine in Rabbit Lacrimal Matrix Using Liquid Chromatography–Tandem Mass Spectrometry6
Quantitation of BCAA and BCKA in plasma and patient-centric dried blood microsamples in a clinical setting6
An Eco-Friendly Ultra-Performance Liquid Chromatography–Mass Spectrometry Method for Quantification of Rivaroxaban and Ticagrelor in Rat Plasma: Grapefruit Interactions6
Rethinking validation paradigms for qPCR and dPCR assays in bioanalysis6
Quantitative polymerase chain reaction in the bioanalytical laboratory and technical and scientific considerations for nonclinical and clinical assay characterization, validation and sample analysis6
Critical reagent considerations for immunogenicity assay development for bispecific biotherapeutic candidates6
Quantification of a promising JNK inhibitor and nitrovasodilator IQ-1 and its major metabolite in rat plasma by LC–MS/MS6
Development and validation of a bioanalytical method to quantify povorcitinib in human skin with clinical application6
A Smartphone Digital Image Colorimetric Method Based on Nanoparticles for Determination of Lamotrigine5
Bioanalysis of tucatinib and metabolite, and a five-way cross-validation to support clinical pharmacokinetic analysis5
Harmonization of Vaccine Ligand Binding Assays Validation5
Novel assay format for total anti-adeno-associated virus antibody detection with low capsid consumption and built-in specificity control5
High-resolution mass spectrometry for glycoproteomics5
Prediction of frozen virus stability based on degradation mechanisms, real-time data and modeling5
Bioanalytical tandem mass spectrometry method for cinacalcet in human plasma: green assessment with advanced metrics5
Fabry Disease Biomarkers in Patients Switched From Enzyme-Replacement Therapy to Migalastat Oral Chaperone Therapy5
Single-Analyte Biomarker Assays for Pharmacodynamic or Safety Assessment During Biotherapeutic Development5
LC–MS Bioanalysis of Protein Biomarkers and Protein Therapeutics in Formalin-Fixed Paraffin-Embedded Tissue Specimens5
Development and validation of highly sensitive ligand binding assay to measure soluble DLL3 concentration in human serum5
2024 White Paper on Recent Issues in Bioanalysis: Three Way-Cross Validation; Urine Clinical Analysis; Automated Methods; Regulatory Queries on Plasma Protein Binding; Automated Biospecimen Management5
A comprehensive LC–MS based study of factors influencing biotinylation of critical reagents5
Pharmacokinetics and apparent Michaelis constant for metabolite conversion of sorafenib in healthy and hepatocellular carcinoma-bearing rats5
Validation and Application of Hybridization Liquid Chromatography-Tandem Mass Spectrometry Methods for Quantitative Bioanalysis of Antisense Oligonucleotides5
LC-MS/MS method for co-estimation of doxorubicin and piperine: formulation development and pharmacokinetic studies5
Development and validation of an LC–MS/MS method for D- and L-2-hydroxyglutaric acid measurement in cerebrospinal fluid, urine and plasma: application to glioma5
LC–MS/MS Methods for Direct Measurement of Sepiapterin and Tetrahydrobiopterin in Human Plasma and Clinical Applications5
Assessing linearity of vaccine immunogenicity assays: application and link with clinical endpoints5
Development of pseudotyped VSV-SARS-CoV-2 spike variants for the assessment of neutralizing antibodies5
Characterization of Murine Lymphocyte Activation and Exhaustion Markers by a 14-Color Flow Cytometry Panel5
A Validated Method for the Determination of Hematocrit in Dried Blood Spots Using Image Analysis5
Insights and Future Trends in Bioanalysis: An Interview With Jing Tu5
Expanding Assay Range to Accommodate a Monoclonal Antibody Therapeutic Quantification in Blood and Cerebrospinal Fluid5
Pitfalls in bioanalytical work with a Japanese CRO or sponsor: from a project risk management perspective5
A Biomarker Assay Validation Approach Tailored to The Context of Use and Bioanalytical Platform5
The acute oral toxicity and pharmacokinetic determination of a novel chloroquinoline hybrid molecule by LC-MS/MS5
When is a sample a urine sample? Markers for urine sample authenticity assessment in sports drug testing5
Detection of Streptococcus anginosus in fecal samples using PCR-CRISPR /Cas12a system5
Mitigation of pre-existing immunogenicity in ADA method development4
Re-thinking the current paradigm for clinical immunogenicity assessment: an update from the discussion in the European Bioanalysis Forum4
Mass spectrometry for clinical bioanalysis without chromatographic separation: bioequivalence for bupropion and its metabolites4
Moving into the cloud: a summary from a European Bioanalysis forum workshop on introducing cloud applications in bioanalytical laboratories4
Research progress of N -nitrosamine detection methods: a review4
Measuring HSD17β13 protein turnover in mouse liver with D 2 O metabolic labeling and hybrid LC-MS4
Multi-residue analysis method based on QuEChERS followed by ultra-high performance liquid chromatography coupled with diode-array detector for pesticides in human serum and breast milk4
Artificial intelligence and blockchain in clinical trials: enhancing data governance efficiency, integrity, and transparency4
Thyroxine Biosensors: A Review on Progress and Challenges4
Utilizing Droplet Digital Polymerase Chain Reaction for siRNA Quantitation in Rodent Plasma and Tissue Via Stem-Loop Reverse Transcription4
Method development and validation for simultaneous analysis of four bile acids as CYP3A drug–drug interaction biomarkers4
Green HPLC method for determination of paracetamol and ibuprofen in human plasma: applications to pharmacokinetics4
Development and Validation of Reversed-Phase-HPLC Method for Simultaneous Quantification of Fulvestrant and Disulfiram in Liposomes4
Direct bioanalysis or indirect calculation of target engagement and free drug exposure: do we apply double standards?4
Low-volume collection devices for longitudinal biomarker monitoring in patient-centric sampling settings4
Volumetric absorptive microsampling–LC–MS/MS assays for quantitation of giredestrant in dried human whole blood4
Simultaneous estimation of donepezil and quercetin using ultra high performance liquid chromatography: pharmaceutical and pharmacokinetic applications in Alzheimer’s disease4
Development and validation of an antidrug antibody assay for TRK-950 using Melon™ gel and SPEAD pretreatment4
BiSim Tool: a binding simulation tool to aid and simplify ligand-binding assay design and development4
A Validated Capillary Microsampling Liquid Chromatography–Tandem Mass Spectrometry Method for Quantification of Antisense Oligonucleotides in Mouse Serum4
Streamlined neutralizing antibody assay development: overcoming serum interference, utilization of DOE and automation4
Integrating metering capabilities to increase the utility of self-collected, dried samples4
Enantioselective electrochemical detection of a L-and D-serine at polyvinylpyrrolidone-modified platinum electrode4
An update on the European Bioanalysis Forum recommendation on singlicate analysis for ligand binding assays: biomarker and anti-drug-antibody assays4
Harmonizing immunogenicity for AAV and LNP/mRNA modalities: best-practice panels for binding, neutralizing, and cellular assays with pre-existing immunity controls4
Development of a validated novel bead extraction method for the detection of anti-PEG antibodies in human serum4
Bioanalysis Rising Star Award 2023: announcing our finalists4
Validated HPLC Method for Ceftriaxone from Dried Blood Spots for Pharmacokinetic Studies and Therapeutic Drug Monitoring in Neonatal Population4
Quantification of MDR-TB drug JBD0131 and its metabolite in plasma via UPLC-MS/MS: application in first-in-human study4
0.07955002784729