Bioanalysis

Article	Citations
Meet the Editorial Board – An Interview with Min Meng and Transitions from Small Regional Labs to Global CRO	37
Biomonitoring of Arsenic, Lead, Manganese and Mercury in Hair from a Presumably Exposed Uruguayan Child Population	29
Volumetric Absorptive Microsampling as An Effective Microsampling Technique for LC–MS/MS Bioanalysis of Biomarkers in Drug Discovery	28
Signal-to-noise Ratio to Assess Magnitude, Kinetics and Impact on Pharmacokinetics of the Immune Response to an Adalimumab Biosimilar	25
Biomarker Context-Of-Use: How Organizational Design Can Impact the Implementation of the Appropriate Biomarker Assay Strategy	25
Degradation of Vancomycin in External Quality Assessment Samples is a Factor to Underestimate Its Concentration	24
Simple Method to Determine the Concentration and Incorporation Ratio of Ruthenium-Labeled Antibodies	23
Bioanalysis by LC-MS/MS and Preclinical Pharmacokinetic Interaction Study of Ribociclib and Oleanolic Acid	21
Adopting ambient ionization mass spectrometry into bioanalytical laboratories	20
Uncovering the Green Frontier: Harnessing Deep Eutectic Solvents for Sustainable Bioanalysis	19
Peripheral blood mononuclear cells isolation from mouse and rabbit blood to quantify active nucleotide and define brincidofovir dose for smallpox	19
Patient-centric clinical trials: collaboration and innovation in bioanalytical and clinical operations	16
Determination of carbamazepine in fingerprints: a feasibility study to evaluate adherence in epilepsy patients	14
Validation of Enantioseparation and Quantitation of an Active Metabolite of Abrocitinib in Human Plasma	14
Selective IgM digestion improves anti-AAV IgG detection in the immune complex assay format	13
Strategy and Validation of a Nonclinical Generic Plug-and-Play Antidrug Antibody Method for Human Monoclonal Antibody Biotherapeutics	13
HPPA as assay substrate for improved capturing of sample variability during cut point analyses in immunogenicity testing	13
Determination of IQZ23 in Rat Plasma using LC-MS/MS: Consideration for Matrix Effect and Internal Standard Interference	12
Handling Unstable Analytes: Literature Review and Expert Panel Survey by the Japan Bioanalysis Forum Discussion Group	12
Recent advances in gold nanoparticle-based colorimetric aptasensors for chemical and biological analyses	12
Whole blood stability in bioanalytical method validation: updated recommendations from the European Bioanalysis Forum	12
A comparison of branched DNA and reverse transcriptase quantitative polymerase chain reaction methodologies for quantitation of lipid nanoparticle encapsulated mRNA	11
A clever evaluation of the antidiabetic medications linagliptin and empagliflozin in bulk and spiked urine samples	11
Diversity and Inclusion in the Bioanalytical Industry: An Interview with Anahita Keyhani	11
Bioanalysis of free antisense oligonucleotide payload from antibody–oligonucleotide conjugate by hybridization LC-MS/MS	11

Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique	11
Bioanalysis Rising Star Award 2024: interviews with the finalists	10
Comparison of Assay Formats Used for the Detection of Pre-Existing Anti-Drug Antibodies Against Monoclonal Antibodies	10
Simultaneous Measurement of Mouse and Human Albumin in Chimeric Mice with Humanized Livers	10
Ligand-binding assays vs chromatographic platforms for oligonucleotide quantification	10
The investigation of connection between anticoagulant therapy and vitamin K homologues in human determined by LC–MS/MS	9
Special Focus Issue - Covid-19: Bioanalytical Considerations, Contributions and Lessons – Part 2	9
An LC–MS/MS Method for Simultaneous Determination of LB-100 and Its Active Metabolite, Endothall, in Human Plasma	9
Method development for the quantification of lead levels in whole blood sampled on Mitra ® with VAMS ® tips by inductively coupled	8
Highlights of the 13th Japan Bioanalysis Forum Symposium	8
Considerations in Designing and Implementing a Bioanalytical Contract Research Organization Key Performance Indicator System	8
Special consideration: commentary on the 2025 FDA Bioanalytical Method Validation for Biomarkers	8
Inception and Development of a LC–MS/MS Assay for the Multiplexed Quantitation of Nine Human Drug Transporter Biomarkers	8
Highlights of the 15th Japan Bioanalysis Forum Symposium	8
A novel LC-MS/MS method for simultaneous estimation of chlordiazepoxide and clidinium in human plasma and its application to pharmacokinetic assessment	8
Transforming drug discovery: the impact of AI and molecular simulation on R&D efficiency	8
Western Blotting: Evolution of an Old Analytical Method To a New Quantitative Tool for Biomarker Measurements	8
Olympic Anti-Doping Laboratory: The Analytical Technological Road From 2016 Rio De Janeiro to 2021 Tokyo	8
Perspectives on a Flexible Strategy for the Management of Nonregulated Bioanalysis	8
Validation of an LC–MS/MS method for the determination of sotorasib, a KRAS G12C inhibitor, in human plasma	8
Determination of meropenem in capillary plasma microsamples using LC–MS/MS	8
Determination of Amphetamines, Opioids, Cocaine Metabolites and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in Urine Using Biocompatible Solid-Phase Microextraction and Ultra-Performance LC–MS/MS	7
A Sensitive, Robust and High-Throughput Isotope Dilution LC–MS/MS Method for Quantifying Three Folate Forms in Serum	7
High Ionic Strength Dissociation Assay Reduces Dimeric Target Interference in Immunogenicity Testing	7
Novel Isoelectric Target Depletion (ITaD) Protocol Reduces the Need for Specific Reagents for Immunogenicity Testing	7
Molecularly Imprinted Electrochemical Biosensor for Thrombin Detection by Comparing Different Monomers	7
Validation of UV–Vis spectrophotometric colorimetric methods for Rifampicin quantification in PBS & biological matrices	7
Internal standard variability: root cause investigation, parallelism for evaluating trackability and practical considerations	7
An interview with Bioanalysis : speaking with the 2025 international reid bioanalytical forum bursary award winners	7
Development and Validation of qPCR Methods for Nucleic Acid Biomarkers as a Drug Development Tool: Points to Consider	7
Upfront Acid Treatment with Low Final pH: The Development and Testing of a Novel Method to Improve Drug Tolerance in Antidrug Antibody Assays	7
Critical Reagent Inventory Management System and Web Portal Specifically Optimized for Supporting External Clients	7
Development of an LC-MS/MS assay to analyze a lipid-conjugated siRNA by solid phase extraction (SPE) in mouse plasma and tissue using a stable isotope labeled internal standard (SILIS)	7
Special Focus Issue - Performing Flow Cytometry in Clinical Trials	6
Comparison of multiple bioanalytical assay platforms for the quantitation of siRNA therapeutics	6
Ocular Bioanalysis of Moxifloxacin and Ketorolac Tromethamine in Rabbit Lacrimal Matrix Using Liquid Chromatography–Tandem Mass Spectrometry	6
Quantitation of BCAA and BCKA in plasma and patient-centric dried blood microsamples in a clinical setting	6
HPLC Method for Simultaneous Estimation of Paclitaxel and Baicalein: Pharmaceutical and Pharmacokinetic Applications	6
Development and validation of bioanalytical methods to support clinical study of disitamab vedotin	6
Revolutionizing depression diagnosis: earwax analysis for cortisol and beyond	6
Comparison of Requirements for Clinical Study of SARS-CoV-2 Antigen Test Kits in China, the USA and Europe	6
Determination of aloesone in rat plasma by LC–MS/MS spectrometry and its application in a pharmacokinetic study	6
DoE-assisted HPLC method development and validation of enzalutamide and repaglinide in rat plasma	6
Perspective on High-Throughput Bioanalysis to Support In Vitro Assays in Early Drug Discovery	6
Quantitative polymerase chain reaction in the bioanalytical laboratory and technical and scientific considerations for nonclinical and clinical assay characterization, validation and sample analysis	5
Development and validation of an LC–MS/MS method for D- and L-2-hydroxyglutaric acid measurement in cerebrospinal fluid, urine and plasma: application to glioma	5
LC–MS Bioanalysis of Protein Biomarkers and Protein Therapeutics in Formalin-Fixed Paraffin-Embedded Tissue Specimens	5
A Biomarker Assay Validation Approach Tailored to The Context of Use and Bioanalytical Platform	5
Rapid Development of Analytical Methods for Evaluating Pandemic Vaccines: A Covid-19 Perspective	5
Quantification of a promising JNK inhibitor and nitrovasodilator IQ-1 and its major metabolite in rat plasma by LC–MS/MS	5

Prediction of frozen virus stability based on degradation mechanisms, real-time data and modeling	5
Greener Bioanalytical Sample Preparation. What is Next?	5
Single-Analyte Biomarker Assays for Pharmacodynamic or Safety Assessment During Biotherapeutic Development	5
Comparative pharmacokinetic study of Anisodamine Hydrobromide tablets and injection in septic acute lung injury rats	5
Effect of Chronopharmacology and Food on in Vivo Pharmacokinetic Profile of Mavacamten	5
Determination of Favipiravir in Human Plasma using Homogeneous Liquid–Liquid Microextraction followed by HPLC/UV	5
Development of LC–MS/MS Method for Cyanoenone Triterpenoid Determination to Support CNS Tissue Distribution Study	5
LC-MS/MS method for co-estimation of doxorubicin and piperine: formulation development and pharmacokinetic studies	5
An Eco-Friendly Ultra-Performance Liquid Chromatography–Mass Spectrometry Method for Quantification of Rivaroxaban and Ticagrelor in Rat Plasma: Grapefruit Interactions	5
LC–MS/MS Methods for Direct Measurement of Sepiapterin and Tetrahydrobiopterin in Human Plasma and Clinical Applications	5
Critical reagent considerations for immunogenicity assay development for bispecific biotherapeutic candidates	5
Role of miRNA-21 in cancer and its application in electrochemical bioanalysis	5
Detection of Streptococcus anginosus in fecal samples using PCR-CRISPR /Cas12a system	5
Bioanalytical tandem mass spectrometry method for cinacalcet in human plasma: green assessment with advanced metrics	5
Development of pseudotyped VSV-SARS-CoV-2 spike variants for the assessment of neutralizing antibodies	4
High-resolution mass spectrometry for glycoproteomics	4
2024 White Paper on Recent Issues in Bioanalysis: Three Way-Cross Validation; Urine Clinical Analysis; Automated Methods; Regulatory Queries on Plasma Protein Binding; Automated Biospecimen Management	4
The acute oral toxicity and pharmacokinetic determination of a novel chloroquinoline hybrid molecule by LC-MS/MS	4
A Smartphone Digital Image Colorimetric Method Based on Nanoparticles for Determination of Lamotrigine	4
A Validated Capillary Microsampling Liquid Chromatography–Tandem Mass Spectrometry Method for Quantification of Antisense Oligonucleotides in Mouse Serum	4
Artificial intelligence and blockchain in clinical trials: enhancing data governance efficiency, integrity, and transparency	4
Quantification of MDR-TB drug JBD0131 and its metabolite in plasma via UPLC-MS/MS: application in first-in-human study	4
Insights and Future Trends in Bioanalysis: An Interview With Jing Tu	4
Validation and Application of Hybridization Liquid Chromatography-Tandem Mass Spectrometry Methods for Quantitative Bioanalysis of Antisense Oligonucleotides	4
Expanding Assay Range to Accommodate a Monoclonal Antibody Therapeutic Quantification in Blood and Cerebrospinal Fluid	4
Novel assay format for total anti-adeno-associated virus antibody detection with low capsid consumption and built-in specificity control	4
A comprehensive LC–MS based study of factors influencing biotinylation of critical reagents	4
Development and validation of highly sensitive ligand binding assay to measure soluble DLL3 concentration in human serum	4
Capillary Electrophoresis Mass Spectrometry for Metabolomics: Reflecting on the Next Steps	4
Pharmacokinetics and apparent Michaelis constant for metabolite conversion of sorafenib in healthy and hepatocellular carcinoma-bearing rats	4
Validated HPLC Method for Ceftriaxone from Dried Blood Spots for Pharmacokinetic Studies and Therapeutic Drug Monitoring in Neonatal Population	4
Thyroxine Biosensors: A Review on Progress and Challenges	4
A Validated Method for the Determination of Hematocrit in Dried Blood Spots Using Image Analysis	4
Assessing linearity of vaccine immunogenicity assays: application and link with clinical endpoints	4
Pitfalls in bioanalytical work with a Japanese CRO or sponsor: from a project risk management perspective	4
Development and validation of an ELISA method for quantification of the anti-HER3 antibody HMBD-001 in human serum	4
Fabry Disease Biomarkers in Patients Switched From Enzyme-Replacement Therapy to Migalastat Oral Chaperone Therapy	4
Bioanalysis of tucatinib and metabolite, and a five-way cross-validation to support clinical pharmacokinetic analysis	4
Harmonization of Vaccine Ligand Binding Assays Validation	4
Utilizing Droplet Digital Polymerase Chain Reaction for siRNA Quantitation in Rodent Plasma and Tissue Via Stem-Loop Reverse Transcription	4
Development and validation of an antidrug antibody assay for TRK-950 using Melon™ gel and SPEAD pretreatment	4
Characterization of Murine Lymphocyte Activation and Exhaustion Markers by a 14-Color Flow Cytometry Panel	4
BiSim Tool: a binding simulation tool to aid and simplify ligand-binding assay design and development	4
Welcome to Volume 14 of Bioanalysis	3
Analytical Considerations to Support Expeditious Formulation Development of Vaccines	3
Multi-residue analysis method based on QuEChERS followed by ultra-high performance liquid chromatography coupled with diode-array detector for pesticides in human serum and breast milk	3
Nitrosamine Impurities: from Raw Materials to Final Drug Product	3
Mass spectrometry for clinical bioanalysis without chromatographic separation: bioequivalence for bupropion and its metabolites	3
Enantioselective electrochemical detection of a L-and D-serine at polyvinylpyrrolidone-modified platinum electrode	3
Comparison of Liquid–Liquid Extraction, Microextraction and Ultrafiltration for Measuring Free Concentrations of Testosterone and Phenytoin	3
With Great Power Comes Great Responsibility: High-Dimensional Spectral Flow Cytometry to Support Clinical Trials	3
2023 White Paper on Recent Issues in Bioanalysis: Deuterated Drugs; LNP; Tumor/FFPE Biopsy; Targeted Proteomics; Small Molecule Covalent Inhibitors; Chiral Bioanalysis; Remote Regulatory Assessments;	3
China's NMPA Perspective on the Clinical Performance of SARS-CoV-2 Antigen Test Reagents	3
Feasibility of using PALSAR technology as a signal amplifier for antibody bridging assay	3
Bioanalysis Rising Star Award 2023: announcing our finalists	3
Large Molecule Bioanalysis by LC–MS: Beyond Simply Quantifying	3
Direct bioanalysis or indirect calculation of target engagement and free drug exposure: do we apply double standards?	3
Advances in green sample preparation methods for bioanalytical laboratories focusing on drug analysis	3
Development of a validated novel bead extraction method for the detection of anti-PEG antibodies in human serum	3
Re-thinking the current paradigm for clinical immunogenicity assessment: an update from the discussion in the European Bioanalysis Forum	3
Green HPLC method for determination of paracetamol and ibuprofen in human plasma: applications to pharmacokinetics	3
Simultaneous estimation of donepezil and quercetin using ultra high performance liquid chromatography: pharmaceutical and pharmacokinetic applications in Alzheimer’s disease	3
Free serum concentrations of antibiotics determined by ultrafiltration: extensive evaluation of experimental variables	3
LC-MS/MS Methods to quantify HCP002 in Human Plasma and Urine: Applications in a Pharmacokinetic Study	3
Testing in the Workplace: Finding a Path Through a Pandemic	3
High-Throughput MS for Intact Protein Analysis	3
Pharmacokinetics and Toxicity Considerations for Antibody–drug Conjugates: An Overview	3
Accelerating isotope dilution LC-MS-based desmosine quantification for estimating elastin turnover	3
Blood Cell Quantification on Dry Blood Samples: Toward Patient-Centric Complete Blood Counts	3
2024 White paper on recent issues in bioanalysis: Impact of LDT in US and IVDR in EU; AI/ML for High Parameter Flow Cytometry; The rise of Olink Technology; CDx for AAV Gene Therapies; Integrative Bio	3
Volumetric absorptive microsampling–LC–MS/MS assays for quantitation of giredestrant in dried human whole blood	3
Singlicate analysis in ADA assays: comparing assay performance in duplicate and singlicate formats	3
Measuring HSD17β13 protein turnover in mouse liver with D 2 O metabolic labeling and hybrid LC-MS	3
Research progress of N -nitrosamine detection methods: a review	3
A Bioanalytical Screening Method for Enterococcus faecalis RNPP-type Quorum Sensing Peptides in Murine Feces	3
Integrating metering capabilities to increase the utility of self-collected, dried samples	3
Development and Validation of Reversed-Phase-HPLC Method for Simultaneous Quantification of Fulvestrant and Disulfiram in Liposomes	3
Lessons Learned from Regulatory Submissions Involving Endogenous Therapeutic Analyte Bioanalysis	3
Quantifying skin permeation of a novel metformin lotion using modified hydrophilic interaction liquid chromatography	3
LC–MS/MS Bioanalytical Method for Quantification of Binimetinib and Venetoclax, and their Pharmacokinetic Interaction	3

Moving into the cloud: a summary from a European Bioanalysis forum workshop on introducing cloud applications in bioanalytical laboratories	3
High-sensitivity Quantification of Antisense Oligonucleotides for Pharmacokinetic Characterization	3
Thalidomide Measurement in Plasma and Dried Plasma Spot by SPE Combined with UHPLC-MS/MS for Therapeutic Drug Monitoring	3
Simultaneous quantitation of tigecycline, meropenem, polymyxin B in plasma, and protein-binding analysis in HSCT patients	3