OOIR: Observatory of International Research

Papers

(The H4-Index of EMBO Molecular Medicine is 43. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
YAP/TAZ and ATF4 drive resistance to Sorafenib in hepatocellular carcinoma by preventing ferroptosis	281
Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology ar	252
Delivery of oligonucleotide‐based therapeutics: challenges and opportunities	200
Blood‐based biomarkers for Alzheimer's disease	163
The rapidly evolving view of lysosomal storage diseases	147
Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia	142
Mechanisms of small cell lung cancer metastasis	120
NAD ⁺ homeostasis in human health and disease	119
Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19	108
Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau	106
The ups and downs of caloric restriction and fasting: from molecular effects to clinical application	100
Urinary proteome profiling for stratifying patients with familial Parkinson’s disease	97
High‐resolution serum proteome trajectories in COVID‐19 reveal patient‐specific seroconversion	94
Emerging roles of ATG7 in human health and disease	93
Systemic inflammation after stroke: implications for post‐stroke comorbidities	92
Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection	86
Decreased serum level of sphingosine‐1‐phosphate: a novel predictor of clinical severity in COVID‐19	73
Fragmentation patterns and personalized sequencing of cell‐free DNA in urine and plasma of glioma patients	72
Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer	70
Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders	68
Tau PET correlates with different Alzheimer’s disease‐related features compared to CSF and plasma p‐tau biomarkers	68
Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads	67
Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers	67
Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer	67
Epithelial response to IFN‐γ promotes SARS‐CoV‐2 infection	63

Improvement of islet transplantation by the fusion of islet cells with functional blood vessels	63
SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models	62
A comparative analysis of remdesivir and other repurposed antivirals against SARS‐CoV‐2	62
LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies	59
Pharmacological reversal of synaptic and network pathology in human MECP2 ‐KO neurons and cortical organoids	59
A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea	59
The state of the art of bispecific antibodies for treating human malignancies	58
Inhibition of NPC1L1 disrupts adaptive responses of drug‐tolerant persister cells to chemotherapy	58
Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis	54
Vegan diet in young children remodels metabolism and challenges the statuses of essential nutrients	53
Very‐low‐carbohydrate diet enhances human T‐cell immunity through immunometabolic reprogramming	51
Psoriatic skin inflammation is promoted by c‐Jun/AP‐1‐dependent CCL2 and IL‐23 expression in dendritic cells	50
Targeted attenuation of elevated histone marks at SNCA alleviates α‐synuclein in Parkinson's disease	50
Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?	49
Fate and propagation of endogenously formed Tau aggregates in neuronal cells	48
Bacterial lysis, autophagy and innate immune responses during adjunctive phage therapy in a child	46
A novel P2X2‐dependent purinergic mechanism of enteric gliosis in intestinal inflammation	46
Humanized COVID‐19 decoy antibody effectively blocks viral entry and prevents SARS‐CoV‐2 infection	44
Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness	43
High‐throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts	43
Pathomechanisms and biomarkers in facioscapulohumeral muscular dystrophy: roles of DUX4 and PAX7	43
Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons	43