OOIR: Observatory of International Research

Papers

(The median citation count of Epigenetics & Chromatin is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review	97
Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation	89
Loss of EZH2-like or SU(VAR)3–9-like proteins causes simultaneous perturbations in H3K27 and H3K9 tri-methylation and associated developmental defects in the fungus Podospora anserina	53
An optimized approach for multiplexing single-nuclear ATAC-seq using oligonucleotide-conjugated antibodies	46
Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation	44
Co-effects of m6A and chromatin accessibility dynamics in the regulation of cardiomyocyte differentiation	44
From compartments to loops: understanding the unique chromatin organization in neuronal cells	38
Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development	30
Chromatin structure and 3D architecture define the differential functions of PU.1 regulatory elements in blood cell lineages	29
Evolutionary adaptation of the Polycomb repressive complex 2	28
Sensitivity of cohesin–chromatin association to high-salt treatment corroborates non-topological mode of loop extrusion	26
Partial erosion on under-methylated regions and chromatin reprogramming contribute to oncogene activation in IDH mutant gliomas	26
Conservation and diversity of the eukaryotic SAGA coactivator complex across kingdoms	25
One-pot universal NicE-seq: all enzymatic downstream processing of 4% formaldehyde crosslinked cells for chromatin accessibility genomics	24
Intrafamily heterooligomerization as an emerging mechanism of methyltransferase regulation	24
Who’s afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data	24
Evaluation of whole-genome DNA methylation sequencing library preparation protocols	23
Development of super-specific epigenome editing by targeted allele-specific DNA methylation	23
Chromatin balances cell redox and energy homeostasis	22
CpG DNA methylation changes during epididymal sperm maturation in bulls	21
Phthalates impact on the epigenetic factors contributed specifically by the father at fertilization	20
Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers	19
Roles of post-translational modifications of UHRF1 in cancer	19
Acquired sperm hypomethylation by gestational arsenic exposure is re-established in both the paternal and maternal genomes of post-epigenetic reprogramming embryos	18
Losing DNA methylation at repetitive elements and breaking bad	17

Heterosis of growth trait regulated by DNA methylation and miRNA in allotriploid fish	16
TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer	16
Manipulating chromatin architecture in C. elegans	16
PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome	15
The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor	15
Impact of chromatin on HIV-1 latency: a multi-dimensional perspective	15
Epigenetic control of dental stem cells: progress and prospects in multidirectional differentiation	14
Mitochondrial supplementation of Sus scrofa metaphase II oocytes alters DNA methylation and gene expression profiles of blastocysts	14
Native and tagged CENP-A histones are functionally inequivalent	14
Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation	14
Structural and functional specificity of H3K36 methylation	13
Knockout tales: the versatile roles of histone H3.3 in development and disease	13
Mechanism of non-coding RNA regulation of DNMT3A	12
TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation	12
Making sense of the linear genome, gene function and TADs	12
Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid model	12
Effects of paternal exposure to cigarette smoke on sperm DNA methylation and long-term metabolic syndrome in offspring	12
Multi-omics analyses of MEN1 missense mutations identify disruption of menin–MLL and menin–JunD interactions as critical requirements for molecular pathogenicity	12
Reinforcement of repressive marks in the chicken primordial germ cell epigenetic signature: divergence from basal state resetting in mammals	12
Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG	11
Premature ovarian insufficiency is associated with global alterations in the regulatory landscape and gene expression in balanced X-autosome translocations	11
Genome-wide DNA methylation patterns in Daphnia magna are not significantly associated with age	11
Prenatal nicotine exposure leads to epigenetic alterations in peripheral nervous system signaling genes in the testis of the rat	11
Hypoxic in vitro culture reduces histone lactylation and impairs pre-implantation embryonic development in mice	10
Differential enrichment of H3K9me3 at annotated satellite DNA repeats in human cell lines and during fetal development in mouse	10
Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers	10
Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data	10
Drosophila architectural proteins M1BP and Opbp cooperatively form the active promoter of a ribosomal protein gene	10
Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression	10
Functions of HP1 proteins in transcriptional regulation	9
Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers	9
Dissecting the Kaiso binding profile in clear renal cancer cells	9
Three putative DNA methyltransferases of Verticillium dahliae differentially contribute to DNA methylation that is dispensable for growth, development and virulence	9
Revealing RCOR2 as a regulatory component of nuclear speckles	9
PCGF6/MAX/KDM5D facilitates MAZ/CDK4 axis expression and pRCC progression by hypomethylation of the DNA promoter	9
The role of MORC3 in silencing transposable elements in mouse embryonic stem cells	9
Correction: Characterizing chromatin interactions of regulatory elements and nucleosome positions, using Hi‑C, Micro‑C, and promoter capture Micro‑C	8
DNA methylation may affect beef tenderness through signal transduction in Bos indicus	8
Histone modification analysis reveals common regulators of gene expression in liver and blood stage merozoites of Plasmodium parasites	8
Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR	8
Folate deficiency reduced aberrant level of DOT1L-mediated histone H3K79 methylation causes disruptive SHH gene expression involved in neural tube defects	8
Analyses of POL30 (PCNA) reveal positional effects in transient repression or bi-modal active/silent state at the sub-telomeres of S. cerevisiae	8
The transgenic IG-DMR sequence of the mouse Dlk1-Dio3 domain acquired imprinted DNA methylation during the post-fertilization period	8
The solid and liquid states of chromatin	8
Dynamics of cattle sperm sncRNAs during maturation, from testis to ejaculated sperm	8
Ageing-associated changes in DNA methylation in X and Y chromosomes	7
High frequency of intron retention and clustered H3K4me3-marked nucleosomes in short first introns of human long non-coding RNAs	7
Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nuclease	7
Imprinted DNA methylation of the H19 ICR is established and maintained in vivo in the absence of Kaiso	7
A standardized nomenclature for mammalian histone genes	7

Deconvolution of the epigenetic age discloses distinct inter-personal variability in epigenetic aging patterns	7
Histone H2A.X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis	7
Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome	7
Multiple distinct domains of human XIST are required to coordinate gene silencing and subsequent heterochromatin formation	6
Chromatin accessibility and cell cycle progression are controlled by the HDAC-associated Sin3B protein in murine hematopoietic stem cells	6
Integrative analysis of gene expression and chromatin dynamics multi-omics data in mouse models of bleomycin-induced lung fibrosis	6
The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex	6
The regional sequestration of heterochromatin structural proteins is critical to form and maintain silent chromatin	6
Characterizing chromatin interactions of regulatory elements and nucleosome positions, using Hi-C, Micro-C, and promoter capture Micro-C	6
DNA methylation correlates of chronological age in diverse human tissue types	6
Long-term exposure to diesel exhaust particles induces concordant changes in DNA methylation and transcriptome in human adenocarcinoma alveolar basal epithelial cells	6
3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk	5
Transcriptional regulation mechanism of PARP1 and its application in disease treatment	5
Nucleophosmin 1 cooperates with the methyltransferase DOT1L to preserve peri-nucleolar heterochromatin organization by regulating H3K27me3 levels and DNA repeats expression	5
Pan-cancer predictions of transcription factors mediating aberrant DNA methylation	5
Correction: Dissecting the Kaiso binding profle in clear renal cancer cells	5
H3K9 post-translational modifications regulate epiblast/primitive endoderm specification in rabbit blastocysts	5
Telomere-specific chromatin capture using a pyrrole–imidazole polyamide probe for the identification of proteins and non-coding RNAs	5
Methylation patterns at the adjacent CpG sites within enhancers are a part of cell identity	5
The MMP-2 histone H3 N-terminal tail protease is selectively targeted to the transcription start sites of active genes	5
FOSL1 is a key regulator of a super-enhancer driving TCOF1 expression in triple-negative breast cancer	5
Correction to: Open chromatin analysis in Trypanosoma cruzi life forms highlights critical differences in genomic compartments and developmental regulation at tDNA loci	4
Placental imprinting of SLC22A3 in the IGF2R imprinted domain is conserved in therian mammals	4
Assessment of relationships between epigenetic age acceleration and multiple sclerosis: a bidirectional mendelian randomization study	4
H3F3A K27M mutations drive a repressive transcriptome by modulating chromatin accessibility independent of H3K27me3 in Diffuse Midline Glioma	4
AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation	4
Live-cell imaging of chromatin contacts opens a new window into chromatin dynamics	4
Crosstalk between non-coding RNAs and programmed cell death in colorectal cancer: implications for targeted therapy	4
O-GlcNAcylation: the sweet side of epigenetics	4
Efficient generation of epigenetic disease model mice by epigenome editing using the piggyBac transposon system	4
Multiple epigenetic factors co-localize with HMGN proteins in A-compartment chromatin	4
Chromatin remodeling and cancer: the critical influence of the SWI/SNF complex	4