OOIR: Observatory of International Research

Papers

(The median citation count of Epigenetics & Chromatin is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers	75
Revealing RCOR2 as a regulatory component of nuclear speckles	71
The role of MORC3 in silencing transposable elements in mouse embryonic stem cells	39
Three putative DNA methyltransferases of Verticillium dahliae differentially contribute to DNA methylation that is dispensable for growth, development and virulence	38
Phthalates impact on the epigenetic factors contributed specifically by the father at fertilization	38
CpG DNA methylation changes during epididymal sperm maturation in bulls	31
Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation	27
The impact of spatial correlation on methylation entropy with application to mouse brain methylome	27
CUT&Tag applied to zebrafish adult tail fins reveals a return of embryonic H3K4me3 patterns during regeneration	26
EphrinA5 regulates cell motility by modulating Snhg15/DNA triplex-dependent targeting of DNMT1 to the Ncam1 promoter	26
Differential enrichment of H3K9me3 at annotated satellite DNA repeats in human cell lines and during fetal development in mouse	25
The role of ribosomal DNA methylation in embryonic development, aging and diseases	24
The MMP-2 histone H3 N-terminal tail protease is selectively targeted to the transcription start sites of active genes	23
Transcriptional regulation mechanism of PARP1 and its application in disease treatment	22
ATAC-seq and RNA-seq analysis unravel the mechanism of sex differentiation and infertility in sex reversal chicken	22
Loss of EZH2-like or SU(VAR)3–9-like proteins causes simultaneous perturbations in H3K27 and H3K9 tri-methylation and associated developmental defects in the fungus Podospora anserina	21
Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers	20
Shedding light on DNA methylation and its clinical implications: the impact of long-read-based nanopore technology	20
Losing DNA methylation at repetitive elements and breaking bad	19
Telomere-specific chromatin capture using a pyrrole–imidazole polyamide probe for the identification of proteins and non-coding RNAs	19
Changes in chromatin accessibility landscape and histone H3 core acetylation during valproic acid-induced differentiation of embryonic stem cells	18
Roles of post-translational modifications of UHRF1 in cancer	18
The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review	17
Expression analysis suggests that DNMT3L is required for oocyte de novo DNA methylation only in Muridae and Cricetidae rodents	17
Functions of HP1 proteins in transcriptional regulation	17

Heterosis of growth trait regulated by DNA methylation and miRNA in allotriploid fish	16
Transcriptional silencing in Saccharomyces cerevisiae: known unknowns	16
H3K9 post-translational modifications regulate epiblast/primitive endoderm specification in rabbit blastocysts	15
A cookbook for DNase Hi-C	15
Acquired sperm hypomethylation by gestational arsenic exposure is re-established in both the paternal and maternal genomes of post-epigenetic reprogramming embryos	14
PCGF6/MAX/KDM5D facilitates MAZ/CDK4 axis expression and pRCC progression by hypomethylation of the DNA promoter	13
Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription	13
Early-life undernutrition induces enhancer RNA remodeling in mice liver	13
An optimized approach for multiplexing single-nuclear ATAC-seq using oligonucleotide-conjugated antibodies	13
Epigene functional diversity: isoform usage, disordered domain content, and variable binding partners	13
Shaking up the silence: consequences of HMGN1 antagonizing PRC2 in the Down syndrome brain	13
Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk	12
Nucleophosmin 1 cooperates with the methyltransferase DOT1L to preserve peri-nucleolar heterochromatin organization by regulating H3K27me3 levels and DNA repeats expression	12
Structural comparisons reveal diverse binding modes between nucleosome assembly proteins and histones	12
The application of epiphenotyping approaches to DNA methylation array studies of the human placenta	12
Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer	12
MMP-2 is a novel histone H3 N-terminal protease necessary for myogenic gene activation	11
Assignment of the somatic A/B compartments to chromatin domains in giant transcriptionally active lampbrush chromosomes	11
Pan-cancer predictions of transcription factors mediating aberrant DNA methylation	11
Manipulating chromatin architecture in C. elegans	11
TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer	10
Native and tagged CENP-A histones are functionally inequivalent	10
PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome	10
The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor	10
The role of Dmnt1 during spermatogenesis of the insect Oncopeltus fasciatus	9
Etiology of super-enhancer reprogramming and activation in cancer	9
CREdb: A comprehensive database of Cis-Regulatory Elements and their activity in human cells and tissues	9
FOSL1 is a key regulator of a super-enhancer driving TCOF1 expression in triple-negative breast cancer	9
Multiple epigenetic factors co-localize with HMGN proteins in A-compartment chromatin	9
Dynamics of cattle sperm sncRNAs during maturation, from testis to ejaculated sperm	9
Research progress of SWI/SNF complex in breast cancer	9
3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk	9
Role of sex in immune response and epigenetic mechanisms	9
Cross-species examination of X-chromosome inactivation highlights domains of escape from silencing	9
Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation	9
Mitochondrial supplementation of Sus scrofa metaphase II oocytes alters DNA methylation and gene expression profiles of blastocysts	8
Efficient generation of epigenetic disease model mice by epigenome editing using the piggyBac transposon system	8
Dissecting the Kaiso binding profile in clear renal cancer cells	8
Analyses of POL30 (PCNA) reveal positional effects in transient repression or bi-modal active/silent state at the sub-telomeres of S. cerevisiae	8
Histone modification analysis reveals common regulators of gene expression in liver and blood stage merozoites of Plasmodium parasites	8
The transgenic IG-DMR sequence of the mouse Dlk1-Dio3 domain acquired imprinted DNA methylation during the post-fertilization period	7
Su(Hw) interacts with Combgap to establish long-range chromatin contacts	7
Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation	7
Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation	7
PARP-dependent and NAT10-independent acetylation of N4-cytidine in RNA appears in UV-damaged chromatin	7
Knockout tales: the versatile roles of histone H3.3 in development and disease	6
H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum	6
Mechanism and functional role of the interaction between CP190 and the architectural protein Pita in Drosophila melanogaster	6
TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation	6
A polycomb group protein EED epigenetically regulates responses in lipopolysaccharide tolerized macrophages	6

Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation	6
AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation	6
Histone crotonylation-centric gene regulation	6
Structural and functional specificity of H3K36 methylation	6
Epigenetic control of dental stem cells: progress and prospects in multidirectional differentiation	6
Co-effects of m6A and chromatin accessibility dynamics in the regulation of cardiomyocyte differentiation	6
Live-cell imaging of chromatin contacts opens a new window into chromatin dynamics	6
From compartments to loops: understanding the unique chromatin organization in neuronal cells	6
H3.3K122A results in a neomorphic phenotype in mouse embryonic stem cells	5
Folate deficiency reduced aberrant level of DOT1L-mediated histone H3K79 methylation causes disruptive SHH gene expression involved in neural tube defects	5
SUMOylated non-canonical polycomb PRC1.6 complex as a prerequisite for recruitment of transcription factor RBPJ	5
Evolutionary adaptation of the Polycomb repressive complex 2	5
Ageing-associated changes in DNA methylation in X and Y chromosomes	5
Dynamic changes in whole genome DNA methylation, chromatin and gene expression during mouse lens differentiation	5
Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development	5
DNA methylation may affect beef tenderness through signal transduction in Bos indicus	5
Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress	5
Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR	5
The solid and liquid states of chromatin	4
Reinforcement of repressive marks in the chicken primordial germ cell epigenetic signature: divergence from basal state resetting in mammals	4
O-GlcNAcylation: the sweet side of epigenetics	4
Effects of paternal exposure to cigarette smoke on sperm DNA methylation and long-term metabolic syndrome in offspring	4