Future Medicinal Chemistry

Article	Citations
CK1 Delta Inhibition: An Emerging Strategy to Combat Neurodegenerative Diseases	62
Proteolysis-Targeting Chimera Molecules Targeting SHP2	55
Novel coumarin linked pyrazoles, thiazoles, and thiadiazoles: synthetic strategies and in vitro antimicrobial investigation	45
Design, Synthesis and Exploration of Novel Triazinoindoles as Potent Quorum-Sensing Inhibitors and Radical Quenchers	37
Chemical and Biological Versatility of Pyrazolo[3,4- d ]Pyrimidines: One Scaffold, Multiple Modes of Action	36
Enhancing the Affinity of Novel GLS1 Allosteric Inhibitors By Targeting Key Residue Lys320	34
Chemical Language Models for Applications in Medicinal Chemistry	33
Panantiviral Agents: Implications for Treating Cancers Associated With Oncoviruses	33
Using Novel Click Chemistry Algorithm to Design D3R Inhibitors As Blood–Brain Barrier Permeants	32
New Thiouracil Derivatives As Histone Deacetylase Inhibitors and Apoptosis Inducers: Design, Synthesis and Anticancer Evaluation	30
Novel Hydroxy- and Amidino-Substituted Benzimidazoles and Benzothiazoles as Antibacterial and Antiproliferative Agents	29
Exploitation of a Novel Allosteric Binding Region in DNA Gyrase and its Implications for Antibacterial Drug Discovery	29
Targeting LRRK2 Mutations in Parkinson's Disease	25
In Silico Multiscale Drug Design to Discover Key Structural Features of Potential JAK2 Inhibitors	25
Welcome to the 16th Volume of Future Medicinal Chemistry	24
Leishmanicidal Activity and 4D Quantitative Structure–Activity Relationship and Molecular Docking Studies of Vanillin-Containing 1,2,3-Triazole Derivatives	24
Advances in Non-Covalent Based Inhibitors Targeting Myc: A Promising Approach for Cancer Treatment	22
PPARγ Transcription Effect on Naturally Occurring O -Prenyl Cinnamaldehydes and Cinnamyl Alcohol Derivatives	22
P2Y14R for Inflammation Therapy: Is It a Promising target?	21
Discovery of α-Helix-Mimicking Sulfono-γ-AApeptides as p53−MDM2 Inhibitors	20
Synthetic Corticosteroids As Tryptophan Hydroxylase Stabilizers	19
COVID-19 Diagnostic Assay Sensitivity: Lessons for the Upcoming Wave Or Next Pandemic	19
Structure-Based Discovery of Thiosemicarbazones As SARS-CoV-2 Main Protease Inhibitors	18
Research Progress on Tamoxifen and Its Analogs Associated With Nuclear Receptors	18
Synthesis and Biological Evaluation of New Antiseizure Compounds Derived From Valproic Acid	18

Development of Small Macrocyclic Kinase Inhibitors	17
Unsymmetrical Thiourea Derivatives: Synthesis and Evaluation as Promising Antioxidant and Enzyme Inhibitors	17
Latest Progress in the Development of Cyclooxygenase-2 Pathway Inhibitors Targeting Microsomal Prostaglandin E 2 Synthase-1	16
Welcome to Volume 14 of Future Medicinal Chemistry	16
Citrate Transporter Inhibitors: Possible New Anticancer Agents	16
New Kinase and HDAC Hybrid Inhibitors: Recent Advances and Perspectives	15
Therapeutic Potential of Vitamin B 1 Derivative Benfotiamine From Diabetes to COVID-19	15
Therapeutic N -Heterocyclic Carbenes: An Interview With Alejandro Bugarin	15
Investigations of New N 1 -Substituted Pyrazoles as Anti-Inflammatory and Analgesic Agents having COX Inhibitory Act	14
Virtual and Augmented Reality Applications in Medicinal Chemistry	14
Potential Strategies for the Management of Adenocarcinoma: a Perspective	14
Multicomponent Reactions As a Privileged Tool for Multitarget-Directed Ligand Strategies in Alzheimer’s Disease Therapy	14
The Connection Between PARP14 and SARS-CoV-2	13
Discovery, Biological Evaluation and Molecular Dynamic Simulations of Butyrylcholinesterase Inhibitors Through Structure-Based Pharmacophore Virtual Screening	13
Antimicrobial, Anticancer and Immunomodulatory Potential of New Quinazolines Bearing Benzenesulfonamide Moiety	13
Design, Synthesis and In Vitro Antiproliferation Activity of Some 2-aryl and -heteroaryl Benzoxazole Derivatives	13
Synthesis and antiproliferative evaluation of novel 3,5,8-trisubstituted coumarins against breast cancer	12
One-step synthesis of diaryloxadiazoles as potent inhibitors of BCRP	12
A novel chromone-based as a potential inhibitor of ULK1 that modulates autophagy and induces apoptosis in colon cancer	12
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity	12
An Emerging Role of KRAS in Biogenesis, Cargo Sorting and Uptake of Cancer-Derived Extracellular Vesicles	12
The anticancer therapeutic potential of pyrimidine–sulfonamide hybrids	11
Synthesis, biological and computational evaluation of benzoxazole hybrid analogs as potential anti-Alzheimer's agents	11
Medicinal chemistry aspects of fat mass and obesity associated protein: structure, function and inhibitors	11
Mitochondrial Dysfunctions Associated With Chronic Respiratory Diseases and Their Targeted Therapies: an Update	11
Synthesis, characterization and biological evaluation of aurones as potential neuroprotective agents	11
Sulfonic Acid: Key Drug Design Elements With potent, broad-ranging Pharmacological Activities	10
Isocoumarins incorporating chalcone moieties act as isoform selective tumor-associated carbonic anhydrase inhibitors	10
Design of SARS-CoV-2 Mpro, PLpro Dual-Target Inhibitors Based on Deep Reinforcement Learning and Virtual Screening	10
Pyrazine-based small molecule kinase inhibitors: clinical applications and patent review (2019–2023)	10
In Vitro Cytotoxic Investigation of Some Synthesized 1,6-Disubstituted-1-Azacoumarin Derivatives as Anticancer Agents	10
Ultrasonic-assisted synthesis and antitumor evaluation of novel variant heterocyclic compounds based on piperidine ring	10
The Structural Basis of Effective LOX-1 Inhibition	9
A Review of Current and Promising Nontuberculous Mycobacteria Antibiotics	9
New (S)-verbenone-isoxazoline-1,3,4-thiadiazole Hybrids: Synthesis, Anticancer Activity and Apoptosis-Inducing Effect	9
STING Upregulation Strategies to Potentiate STING Immunotherapy	9
Discovery of 1,5-diaryl-1,2,4-triazole Derivatives as Myoferlin Inhibitors and Their Antitumor Effects in Pancreatic Cancer	9
Small-Molecule Oligonucleotides As Smart Modality for Antiviral Therapy: A Medicinal Chemistry Perspective	9
Combining EGFR Inhibitors With SHP2 Or LSD1 Inhibitors to Overcome Multidrug Resistance in Cancer	9
Pyrazole: an Emerging Privileged Scaffold in Drug Discovery	9
Design and Synthesis of Selective FLT3 Inhibitors Via Exploration of Back Pocket II	9
FAK Inhibitors As Promising Anticancer Targets: Present and Future Directions	8
Synthesis, Molecular Modeling and Cholinesterase Inhibitory Effects of 2-Indolinone-Based Hydrazinecarbothioamides	8
Synthesis and Molecular Modeling Studies of 1-Benzyl-2-Indolinones As Selective AChE Inhibitors	8
Novel 4-Aminoquinoline Analogs Targeting the HIF-1α Signaling Pathway	8
Selection of SARS-CoV-2 Main Protease Inhibitor Using Structure-Based Virtual Screening	8
Novel Pyrimido-Pyridazine Derivatives: Design, Synthesis, Anticancer Evaluation and In Silico Studies	8
Novel Amodiaquine Analogues to Treat Cervical Cancer and Microbial Infection in the Future	8
Novel 3-substituted coumarins inspire a custom pharmacology prediction pipeline: an anticancer discovery adventure	7
Novel inhibitors of PARP1 and PARP14: design, synthesis, and potentiation of cisplatin efficacy in cancer	7

Sulfonamide-salicylaldehyde Imines Active Against methicillin- and trimethoprim/sulfonamide-resistant Staphylococci	7
Rational Design of Peptide Inhibitors Targeting HSP90–CDC37 Protein–Protein Interaction	7
Identification of Sulfonamide-Based Butyrylcholinesterase Inhibitors Using Machine Learning	7
Targeting Tuberculosis – An Interview With Robert Abramovitch	7
New pyrano-pyridine conjugates as potential anticancer agents: design, synthesis and computational studies	7
The Role of microRNA-21 in the Onset and Progression of Cancer	7
Novel candidates synthesis of indenopyrazole, indenoazine and indenothiophene, with anticancer and in silico studies	7
Novel Anthraquinone Derivatives Trigger Endoplasmic Reticulum Stress Response and Induce Apoptosis	7
Cheminformatics-driven Discovery of Hit Compounds Against Paracoccidioides spp.	7
Advanced Drug Delivery Systems Targeting NF-κB in Respiratory Diseases	7
Design, synthesis and evaluation of novel norfloxacin analogs as potent anticancer and antioxidant agents	7
Design and synthesis of new nicotinamides as immunomodulatory VEGFR-2 inhibitors and apoptosis inducers	7
Structure-Based Molecular Insights Into Matrix Metalloproteinase Inhibitors in Cancer Treatments	7
Super-Conserved Receptors Expressed in the Brain: Biology and Medicinal Chemistry Efforts	7
The Synthesis and Effects of a Novel TRPC6 inhibitor, BP3112, on Hepatocellular Carcinoma	7
Combining Structure-Based and 3D QSAR Pharmacophore Models to Discover Diverse Ligands Against EGFR in Oral Cancer	7
Benzimidazole-acrylonitrile hybrid derivatives act as potent urease inhibitors with possible fungicidal activity	7
Treatment of Rheumatoid Arthritis With Curcumin Analog 3,5-bis(arylidene)-4-piperidone	6
Repurposing Dyphylline as a Pan-Coronavirus Antiviral Therapy	6
Novel Benzimidazole Derivatives as Effective Inhibitors of Prolyl Oligopeptidase: Synthesis, in Vitro and in Silico Analysis	6
Organotellurium (IV) complexes as anti-malarial agents: synthesis, characterization and computational insights	6
In vivo evaluation of novel synthetic pyrazolones as CDK9 inhibitors with enhanced pharmacokinetic properties	6
Biological and computational evaluation of novel benzofuranyl derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors	6
Novel Set of Highly Substituted Bis-Pyridines: Synthesis, Molecular Docking and Drug-Resistant Antibacterial Profile	6
A Systematic Review of carbohydrate-based Bioactive Molecules for Alzheimer’s Disease	6
Exploring biological activities of novel Schiff bases derived from amlodipine and in silico molecular modeling studies	6
New Horizons in Lung Cancer Management Through ATR/CHK1 Pathway Modulation	6
Network Analysis and Ligand-Based Pharmacophore Modeling for Discovery of Small Molecule Against Glioblastoma Multiforme	6
Naphthoquinone fused diazepines targeting hyperamylasemia: potential therapeutic agents for diabetes and cancer	6
The Story of EGFR: From Signaling Pathways to a Potent Anticancer Target	6
Corrigendum	6
The emerging field of senotherapeutic drugs	6
Novel Inhibitors of the Renal Inward Rectifier Potassium Channel of the Mosquito Vector Aedes Aegypti	5
Discovery of Novel Covalent Inhibitors of DJ-1 Through Hybrid Virtual Screening	5
Barbiturate–sulfonate hybrids as potent cholinesterase inhibitors: design, synthesis and molecular modeling studies	5
Current landscape of tropomyosin receptor tyrosine kinase inhibitors	5
Synthesis, in vitro and in silico anticancer evaluation of novel pyridin-2-yl estra-1,3,5(10)-triene derivatives	5
Synergistic effect of new pyrimidine derivative with oxacilin against methicillin-resistant Staphylococcus aureus	5
G-quadruplex Ligands As Therapeutic Agents Against cancer, Neurological Disorders and Viral Infections	5
Synthesis, crystal structure, biological and docking studies of 5-hydroxy-2-{[(2-methylpropyl)iminio]methyl}phenolate	5
Propargylamine: an Important Moiety in Drug Discovery	5
Thiosemicarbazones Reprogram Pancreatic Cancer Bidirectional Oncogenic Signaling Between Cancer Cells and Stellate Cells to Suppress Desmoplasia	5
Design, Synthesis and Biological Evaluation of Novel Indanones Derivatives As Potent Acetylcholinesterase/Monoamine Oxidase B Inhibitors	5
The Discovery and Development of Transthyretin Amyloidogenesis Inhibitors: What are the Lessons?	5
Antimicrobial Activity of Carvacrol and Its Derivatives on Mycobacterium Spp.: Systematic Review of Preclinical Studies	5
Chitosan–maleic Acid Conjugate As Potential Excipient Candidate for Oral Drug delivery?	5
Synthetic benzofuran-linked Chalcones With Dual Actions: a Potential Therapeutic Approach to Manage Diabetes Mellitus	5
Exploring of novel oxazolones and imidazolones as anti-inflammatory and analgesic candidates with cyclooxygenase inhibitory action	5
Non-Regioselective Functionalization: An Underestimate Chemical Diversity Generator in Medicinal Chemistry	5
Dual VEGFR-2 and EGFR T790M inhibitors of phenyldiazenes: anticancer evaluations, ADMET, docking, design and synthesis	5
Molecular docking, derivatization, characterization and biological assays of amantadine	5
Evaluation of Synthetic Aminoquinoline Derivatives As Urease Inhibitors: In Vitro , In Silico and Kinetic Studies	5
Docking and Antibacterial Activity of Novel Nontoxic 5-Arylidenepyrimidine-Triones as Inhibitors of NDM-1 and MetAP-1	5
Discovery of New VEGFR-2 Inhibitors and Apoptosis inducer-based thieno[2,3- d ]pyrimidine	5
Structural Insight Into SSE15206 in Complex With Tubulin Provides a Rational Design for Pyrazolinethioamides As Tubulin Polymerization Inhibitors	5
Insight on novel oxindole conjugates adopting different anti-inflammatory investigations and quantitative evaluation	5
Synthesis and interest in medicinal chemistry of β-phenylalanine derivatives (β-PAD): an update (2010–2022)	5
Harnessing molecular hybridization approach to discover novel quinoline EGFR-TK inhibitors for cancer treatment	5
Discovery of novel ULK1 inhibitors through machine learning-guided virtual screening and biological evaluation	5
Biochemical evaluation of novel thiazolone derivatives as dual α-glucosidase/α-amylase inhibitors, anti-inflammatory agents	5
Challenges and Opportunities for In Vivo PROTAC Delivery	5
Human Sirtuin 2 inhibitors, Their Mechanisms and Binding Modes	5
Special Focus Issue – Targeted Protein Degradation: A New Paradigm in Medicinal Chemistry	5
Serendipitous Identification of Phenylhydrazine Derivatives As Potent Inhibitors of carbapenem-resistant Acinetobacter Baumannii	4
Targeting Mucin Hypersecretion in COVID-19 Therapy	4
The design and development of LRRK2 inhibitors as novel therapeutics for Parkinson’s disease	4
Structure-Guided Discovery of Adenosine Triphosphate-Competitive Casein Kinase 2 Inhibitors	4
Pharmaceutical technological trends containing flavonoids: a patent review	4
Recent Advances in Oxazolidinones as Antituberculosis Agents	4
KSHV-Specific Antivirals Targeting the Protein–DNA Interaction of the Latency-Associated Nuclear Antigen	4
Discovery of New thieno[2,3- d ]pyrimidines as EGFR Tyrosine Kinase Inhibitors for Cancer Treatment	4
Synthesis of New Hexahydropyrimido[1,2- a ]azepine Derivatives Bearing Functionalized Aryl and Heterocyclic Moieties As Anti-Inflammatory Agents	4
Rapidly Evolving First-Line Therapy Using Checkpoint Inhibitors in Metastatic Renal Cell Cancer	4
Benzo[ d ]thiazole-2-Carboxamides As New Antituberculosis Chemotypes Inhibiting Mycobacterial ATP Phosphoribosyl Transferase	4
Salvianolic Acid B Noncovalently Interacts With Disordered c-Myc: A Computational and Spectroscopic-Based Study	4
An Insight Into the Structure–Activity Relationship Studies of Anticancer Medicinal Attributes of 7-Azaindole Derivatives: A Review	4
Epigenetics: rethinking of drug research and development	4
Inhibiting the Metallo-β-lactamases: Challenges and Strategies to Overcome Bacterial β-lactam Resistance	4
Establishment of Models for Reliability Evaluation of 3CLpro Ligand-Receptor Complexes With Different Binding Sites	4
Synthesis of Hydrazinyl–Thiazole Ester Derivatives, in Vitro Trypanocidal and Leishmanicidal Activities	4

Comprehensive drug-like assessment of pyridine carbothioamide analogs: from molecular modeling to in-vivo evaluation	4
New pyrrolopyridine-based Thiazolotriazoles As Diabetics Inhibitors: Enzymatic Kinetics and In Silico Study	4
Versatile Tools of Synthetic Biology Applied to Drug Discovery and Production	4
Key molecular scaffolds in the development of clinically viable α-amylase inhibitors	4
Artificial intelligence-guided Approach for Efficient Virtual Screening of Hits Against Schistosoma Mansoni	4
Novel HIF-1α Inhibitor CDMP-TQZ for Cancer Therapy	4
Literature-Based Drug–Drug Similarity for Drug Repurposing: Impact of Medical Subject Headings Term Refinement and Hierarchical Clustering	4
A New Class of 5-HT 1A Receptor Antagonists With Procognitive and Antidepressant Properties	4
Restoration of p53 Functions By Suppression of mortalin–p53 Sequestration: an Emerging Target in Cancer Therapy	4
Therapeutic targeting of neuroinflammation in methamphetamine use disorder	4
Expanding potential of quinoline hydrazide/hydrazone derivatives as anticancer agents	4
5,7,3′,4′-Tetramethoxyflavone Ameliorates Cholesterol Dysregulation by Mediating SIRT1/FOXO3a/ABCA1 Signaling in Osteoarthritis Chondrocytes	4
Rh(III) and Ru(II) Complexes With Phosphanyl–Alkylamines: Inhibition of DNA Synthesis Induced By Anticancer Rh Complex	4
Design, Synthesis, Biological Evaluation and Docking Study of Novel Quinazoline Derivatives As EGFR-TK Inhibitors	4
Camptothecin: a key building block in the design of anti-tumor agents	4
Design, Synthesis and Anticancer Evaluation of Some Novel 7-Hydroxy-4-Methyl-3-Substituted Benzopyran-2-One Derivatives	4
Targeting undruggable protein KRAS for cancer therapy: novel opportunities and challenges	4
Tetrahydroquinoline: An Efficient Scaffold As mTOR Inhibitor for the Treatment of Lung Cancer	4
Kaempferol Ameliorates the Regulatory Effects of PVT1 / miR-214 on Epithelial–Mesenchymal Transition Through the PAK4/β-catenin Axis in SR	4
Engineering ‘Enzymelink’ for Screening Lead Compounds to Inhibit mPGES-1 while Maintaining Prostacyclin Synthase Activity	4
Identification of a Novel Antifungal Backbone of Naphthalimide Thiazoles with Synergistic Potential for Chemical and Dynamic Treatment	4
Targeting FGL2, a Molecular Drug Target for Glioblastoma, With Natural Compounds Through Virtual Screening Method	4
H 2 S-releasing Molecules in Pharmaceutical Development	4
Computational Insights Into Novel Inhibitor Indole-Heterocycle Specific Against Glycogen Phosphorylase Isoenzymes Interaction Mechanism	4
PROTACs in the treatment of viral diseases	4
Challenging Breast Cancer Through Novel sulfonamide–pyridine Hybrids: design, synthesis, Carbonic Anhydrase IX Inhibition and Induction of Apoptosis	4
Synthesis of new coumarin derivatives and assessment of their antimicrobial efficacy	4
Cyclin-Dependent Kinases As Potential Targets for Colorectal Cancer: Past, Present and Future	4
Synthesis of Ponatinib Analogues As Novel Inhibitors of Leukemia Stem Cells	3
Pyrazoline Scaffold: Hit Identification to Lead Synthesis and Biological Evaluation As Antidiabetic Agents	3
Minimal Screening Requirements for Identifying Highly Promiscuous Kinase Inhibitors	3
Curcumin-based Nanoformulations As an Emerging Therapeutic Strategy for Inflammatory Lung Diseases	3
Development and Implementation of an enterprise-wide Predictive Model for Early absorption, distribution, Metabolism and Excretion Properties	3
Functional Characterization of HIC, a P2Y1 agonist, As a p53 Stabilizer for Prostate Cancer Cell Death Induction	3
Synthesis and Antimicrobial Activity of Thiophene-Based Heterocycles Derived from Thiophene-2-Carbohydrazide	3
Discovery of Novel STAT3 DNA Binding Domain Inhibitors	3
Synthesis, Anticancer Activity, SAR and Binding Mode of Interaction Studies of Substituted Pentanoic Acids: Part II	3
Pyrimido[4,5-b]indole Derivatives Bearing 1,2,4-oxadiazole Moiety As MDM2 Inhibitor Candidates in Cancer Treatment	3
Synthesis of quercetin derivatives as cytotoxic against breast cancer MCF-7 cell line in vitro and in silico studies	3
Therapeutic potential of chalcone-1,2,3-triazole hybrids as anti-tumour agents: a systematic review and SAR studies	3
Synthesis and Anti-Ovarian Cancer Effects of Benzimidazole-2-Substituted Pyridine and Phenyl Propenone Derivatives	3
Basic nitrogen (BaN): a ‘privileged element’ in medicinal chemistry	3
Fluorinated building blocks in drug design: new pathways and targets	3
PROTAC Cell Permeability and Oral Bioavailability: A Journey Into Uncharted Territory	3
Development of Novel Anti-Infective and Antioxidant Azole Hybrids using a Wet and Dry Approach	3
α -amylase Inhibition and In Silico Studies of Novel Naphtho[2,3- d ]imidazole-4,9-Dione Linked N	3
Synthesis of Quercetin–Iron (Fe) Complex and Its In Silico and In Vitro Confirmation Towards Antibacterial Activity	3
Green Synthesis of Nonprecious Metal-Doped Copper Hydroxide Nanoparticles for Construction of a Dopamine Sensor	3
Latest Advances in Specific Inhibition of Tumor-Associated Carbonic Anhydrases	3
Advances in AR-Targeting Chimeras: A Case Study of proteolysis-targeting Chimeras From Bench to Bedside	3
Novel Xylenyl-Spaced Bis-Thiazoles/Thiazines: Synthesis, Biological Profile as Herpes Simplex Virus Type 1 Inhibitors and in Silico Simulations	3
Inherent Efficacies of Pyrazole-Based Derivatives for Cancer Therapy: The Interface Between Experiment and In Silico	3
Selected Heterocycles for the Development of Pyrophosphate Mimics	3
Bacterial Carbonic Anhydrases: Underexploited Antibacterial Therapeutic Targets	3
A series of benzensulfonamide derivatives as new potent carbonic anhydrase IX and XII inhibitors	3
Diaminomaleonitrile Derivatives as new Potential Antichagasic Compounds: A Study of Structure–Activity Relationships	3
Synthesis, anticancer activity, docking and computational studies of new pyridyl-glycosyl hybrids and acyclic analogs	3
Transition metal complexes: a new generation of anticancer drugs	3
Synthesis and In Vitro Studies for Structure-Based Design of Novel Chalcones As Antitubercular Agents Targeting InhA	3
New 1,3,4-thiadiazoles Derivatives: Synthesis, Antiproliferative Activity, Molecular Docking and Molecular Dynamics	3
Current Development of Pyrazole–Azole Hybrids With Anticancer Potential	3
Resistant Starch: Ideal Candidate for the Enteric Coating of NSAIDs?	3
Novel Antimicrobial Iodo-Dihydro-Pyrrole-2-One Compounds	3
Design, synthesis and inhibition evaluation of novel chalcone amide α-glucosidase inhibitors	3
HDAC8 As an Emerging Target in Drug Discovery With Special Emphasis on Medicinal Chemistry	3
Targeting FGFRs for Tumor Therapy: Current Status and Novel Strategies	3
Hitting Drug-Resistant Malaria Infection With Triazole-Linked Flavonoid–Chloroquine Hybrid Compounds	3
Novel Trypanocidal Thiophen-Chalcone Cruzain Inhibitors: Structure- and Ligand-Based Studies	3
One-Pot Multicomponent Synthesis of Novel Pyridine Derivatives for Antidiabetic and Antiproliferative Activities	3
Parasitic Sirtuin 2 As an Opportunity in Drug Discovery	3
Exploring the therapeutic potential of cinnamoyl derivatives in attenuating inflammation in lipopolysaccharide-induced Caco-2 cells	3
Recent Advances in Quinolone Hybrids With Potential Antibacterial Activity Against drug-resistant Bacteria	3
New insides into chimeric and hybrid azines derivatives with antifungal activity	2
Novel Pyrazoles As Potent Growth Inhibitors of Staphylococci, Enterococci and Acinetobacter Baumannii Bacteria	2
The contemplation of amylose for the delivery of ulcerogenic nonsteroidal anti-inflammatory drugs	2
Computational Repurposing of Benzimidazole Anthelmintic Drugs As Potential Colchicine Binding Site Inhibitors	2
Designing HDAC-PROTACs: Lessons Learned So Far	2
Indole–pyridine Carbonitriles: Multicomponent Reaction Synthesis and bio-evaluation As Potential Hits Against Diabetes Mellitus	2
HIV-1 Capsid Inhibitors: A Sword to Destroy the Virus	2
Synthesis of novel hybrids of 1,2,3-triazoles-hydrazone: targeting cholinesterases and Alzheimer's related genes	2
Recent development of azole–sulfonamide hybrids with the anticancer potential	2
Novel 1,2,4-triazoles as selective carbonic anhydrase inhibitors showing ancillary anticathepsin B activity	2
Synthesis and HDAC1 Inhibitory Activity of a Novel Series of Coumarin-Based Amide Derivatives for Treatment of Cancer	2
Anti-proliferation evaluation of new derivatives of indole-6-carboxylate ester as receptor tyrosine kinase inhibitors	2
Exploring the Putative Mechanism of Allosteric Modulations By Mixed-Action Kappa/Mu Opioid Receptor Bitopic Modulators	2
Elongation on Aliphatic Chain Improves Selectivity of 2-Hydroxy-3,4,6-Trimethoxyphenyl Chalcone on Trypanosoma Cruzi	2
Selective CDK9 Degradation Using a Proteolysis-Targeting Chimera (PROTAC) Strategy	2
In vitro α-glucosidase, docking and density functional theory studies on novel azide metal complexes	2
Design and synthesis of novel coumarin–benzimidazole hybrids as human galectin-1 inhibitors	2
Rifamycins: Do not Throw the Baby out with the bathwater. Is Rifampicin Still an Effective Anti-Tuberculosis Drug?	2
Discovery of Novel and Potent InhA Inhibitors By an In Silico Screening and Pharmacokinetic Prediction	2
Flavonoid Diversity and Roles in the Lipopolysaccharide-Mediated Inflammatory Response of Monocytes and Macrophages	2
Development and In Vivo Evaluation of Fused Benzazole Analogs of Anti-Melanoma Agent HA15	2
Evaluation of 2,3-Dihydroimidazo[2,1- b ]oxazole and Imidazo[2,1– b ]oxazole Derivatives As Chemotherapeutic Agents	2
Recent Progress in Small-Molecule Inhibitors for Critical Therapeutic Targets of Necroptosis	2