OOIR: Observatory of International Research

Papers

(The H4-Index of Future Medicinal Chemistry is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Sulfonamide-salicylaldehyde Imines Active Against methicillin- and trimethoprim/sulfonamide-resistant Staphylococci	58
Super-Conserved Receptors Expressed in the Brain: Biology and Medicinal Chemistry Efforts	57
Novel Set of Highly Substituted Bis-Pyridines: Synthesis, Molecular Docking and Drug-Resistant Antibacterial Profile	57
In vivo evaluation of novel synthetic pyrazolones as CDK9 inhibitors with enhanced pharmacokinetic properties	52
Design of SARS-CoV-2 Mpro, PLpro Dual-Target Inhibitors Based on Deep Reinforcement Learning and Virtual Screening	51
Biological and computational evaluation of novel benzofuranyl derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors	44
Combining EGFR Inhibitors With SHP2 Or LSD1 Inhibitors to Overcome Multidrug Resistance in Cancer	44
Identification of Sulfonamide-Based Butyrylcholinesterase Inhibitors Using Machine Learning	42
Citrate Transporter Inhibitors: Possible New Anticancer Agents	40
Therapeutic N -Heterocyclic Carbenes: An Interview With Alejandro Bugarin	39
The Connection Between PARP14 and SARS-CoV-2	38
Targeting Tuberculosis – An Interview With Robert Abramovitch	36
Selection of SARS-CoV-2 Main Protease Inhibitor Using Structure-Based Virtual Screening	34
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity	34
Investigations of New N ¹ -Substituted Pyrazoles as Anti-Inflammatory and Analgesic Agents having COX Inhibitory Act	31
Combining Structure-Based and 3D QSAR Pharmacophore Models to Discover Diverse Ligands Against EGFR in Oral Cancer	28
5,7,3′,4′-Tetramethoxyflavone Ameliorates Cholesterol Dysregulation by Mediating SIRT1/FOXO3a/ABCA1 Signaling in Osteoarthritis Chondrocytes	28
Design and synthesis of new nicotinamides as immunomodulatory VEGFR-2 inhibitors and apoptosis inducers	28
Barbiturate–sulfonate hybrids as potent cholinesterase inhibitors: design, synthesis and molecular modeling studies	27
HDAC8 As an Emerging Target in Drug Discovery With Special Emphasis on Medicinal Chemistry	26
Rh(III) and Ru(II) Complexes With Phosphanyl–Alkylamines: Inhibition of DNA Synthesis Induced By Anticancer Rh Complex	23
Synergistic effect of new pyrimidine derivative with oxacilin against methicillin-resistant Staphylococcus aureus	23
Advances in AR-Targeting Chimeras: A Case Study of proteolysis-targeting Chimeras From Bench to Bedside	22
Design, synthesis and inhibition evaluation of novel chalcone amide α-glucosidase inhibitors	22
Computational Insights Into Novel Inhibitor Indole-Heterocycle Specific Against Glycogen Phosphorylase Isoenzymes Interaction Mechanism	22