OOIR: Observatory of International Research

Papers

(The H4-Index of Future Medicinal Chemistry is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
An overview of drug discovery and development	114
Ligand and structure-based virtual screening applied to the SARS-CoV-2 main protease: an in silico repurposing study	66
10 years into the resurgence of covalent drugs	65
Utilizing the CF₂H moiety as a H-bond-donating group in drug discovery	58
De novodesign of new chemical entities for SARS-CoV-2 using artificial intelligence	53
N-heterocyclic carbene-metal complexes as bio-organometallic antimicrobial and anticancer drugs, an update (2015–2020)	49
Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics	47
Antiproliferative effects of boswellic acid-loaded chitosan nanoparticles on human lung cancer cell line A549	46
Computational repurposing of benzimidazole anthelmintic drugs as potential colchicine binding site inhibitors	46
Tackling SARS-CoV-2: proposed targets and repurposed drugs	43
Anthraquinone: a promising scaffold for the discovery and development of therapeutic agents in cancer therapy	37
Deep learning approaches in predicting ADMET properties	35
Drugging all RAS isoforms with one pocket	34
HeroMDAnalysis: an automagical tool for GROMACS-based molecular dynamics simulation analysis	33
New chalcone-type compounds and 2-pyrazoline derivatives: synthesis and caspase-dependent anticancer activity	32
Structural and functional regulation of lactate dehydrogenase-A in cancer	32
TGF-β in renal fibrosis: triumphs and challenges	31
Novel carbonic anhydrase inhibitors	31
The role of microRNA-21 in the onset and progression of cancer	31
An unexpected discovery toward novel membrane active sulfonyl thiazoles as potential MRSA DNA intercalators	29
Targeting adhesion in fungal pathogen Candida albicans	27
NovelN-bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis,in vitroandin silicostudies	26
Multiple ways to kill bacteria via inhibiting novel cell wall or membrane targets	26
Mechanisms of ebselen as a therapeutic and its pharmacology applications	26
Recent development in acetyl-CoA carboxylase inhibitors and their potential as novel drugs	25