OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Brain is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Interleukin-17 induced by cumulative mild stress promoted depression-like behaviors in young adult mice	69
Alterations in the gut microbiota and metabolite profiles in the context of neuropathic pain	48
Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply	45
Blood–brain barrier: emerging trends on transport models and new-age strategies for therapeutics intervention against neurological disorders	45
Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis	43
Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J mice: a challenge against conventiona	40
Antibiotics-induced intestinal dysbacteriosis caused behavioral alternations and neuronal activation in different brain regions in mice	34
GABAergic neuron-specific whole-brain transduction by AAV-PHP.B incorporated with a new GAD65 promoter	33
Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1	32
Central and peripheral contributions of T-type calcium channels in pain	31
S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS	30
Region-specific distribution of Olig2-expressing astrocytes in adult mouse brain and spinal cord	30
Roles of palmitoylation in structural long-term synaptic plasticity	29
Translational changes induced by acute sleep deprivation uncovered by TRAP-Seq	28
Increased O-GlcNAcylation of Drp1 by amyloid-beta promotes mitochondrial fission and dysfunction in neuronal cells	28
Neuronal excitatory-to-inhibitory balance is altered in cerebral organoid models of genetic neurological diseases	27
Progress on the roles of MEF2C in neuropsychiatric diseases	27
Circadian rhythms in the blood–brain barrier: impact on neurological disorders and stress responses	26
Toll-like receptors and their role in neuropathic pain and migraine	25
Assessing the effect of interaction between C-reactive protein and gut microbiome on the risks of anxiety and depression	24
The role m6A RNA methylation is CNS development and glioma pathogenesis	24
The voltage-gated proton channel Hv1 promotes microglia-astrocyte communication and neuropathic pain after peripheral nerve injury	24
Altered hippocampal transcriptome dynamics following sleep deprivation	23
Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia	23
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain	22

CCL2 facilitates spinal synaptic transmission and pain via interaction with presynaptic CCR2 in spinal nociceptor terminals	21
Proteomic insights into synaptic signaling in the brain: the past, present and future	21
The terpenes camphene and alpha-bisabolol inhibit inflammatory and neuropathic pain via Cav3.2 T-type calcium channels	21
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy	20
Functional organization of the midbrain periaqueductal gray for regulating aversive memory formation	20
The dual roles of autophagy and the GPCRs-mediating autophagy signaling pathway after cerebral ischemic stroke	20
Beta amyloid deposition and cognitive decline in Parkinson’s disease: a study of the PPMI cohort	20
Intranasal oxytocin administration ameliorates social behavioral deficits in a POGZWT/Q1038R mouse model of autism spectrum disorder	20
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons	19
Non-SUMOylated CRMP2 decreases NaV1.7 currents via the endocytic proteins Numb, Nedd4-2 and Eps15	19
The role of triggering receptor expressed on myeloid cells-1 (TREM-1) in central nervous system diseases	19
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8+ T cells	18
Impaired pattern separation in Tg2576 mice is associated with hyperexcitable dentate gyrus caused by Kv4.1 downregulation	18
Relief of neuropathic pain by cell-specific manipulation of nucleus accumbens dopamine D1- and D2-receptor-expressing neurons	18
A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro	18
Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson’s disease model	18
Optogenetics: implications for Alzheimer’s disease research and therapy	17
Caveolin-1 deficiency impairs synaptic transmission in hippocampal neurons	17
APOE genotype dependent molecular abnormalities in the cerebrovasculature of Alzheimer’s disease and age-matched non-demented brains	17
Fibroblasts from idiopathic Parkinson’s disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2	17
Optimization of protocols for pre-embedding immunogold electron microscopy of neurons in cell cultures and brains	17
Retrosplenial cortex in spatial memory: focus on immediate early genes mapping	17
GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis	17
Long-range GABAergic projections from the nucleus of the solitary tract	17
Aversive emotion rapidly activates orexin neurons and increases heart rate in freely moving mice	16
Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons	16
Modeling PTEN overexpression-induced microcephaly in human brain organoids	16
Schizophrenia risk ZNF804A interacts with its associated proteins to modulate dendritic morphology and synaptic development	16
Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice	16
Diverse inflammatory threats modulate astrocytes Ca2+ signaling via connexin43 hemichannels in organotypic spinal slices	16
Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice	16
Distribution of five clinically important neuroglial proteins in the human brain	16
Reversibility of motor dysfunction in the rat model of NGLY1 deficiency	16
Altered functional connectivity between hypothalamus and limbic system in fibromyalgia	15
The Sigma 2 receptor promotes and the Sigma 1 receptor inhibits mu-opioid receptor-mediated antinociception	15
Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150glued	15
Conditional Pten knockout in parvalbumin- or somatostatin-positive neurons sufficiently leads to autism-related behavioral phenotypes	15
2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors	15
The parabrachial-to-amygdala pathway provides aversive information to induce avoidance behavior in mice	15
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression	14
Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer’s disease	14
Further evidence that CP-AMPARs are critically involved in synaptic tag and capture at hippocampal CA1 synapses	14
Disruption of the astrocyte–neuron interaction is responsible for the impairments in learning and memory in 5XFAD mice: an Alzheimer’s disease animal model	13
Decreased in vivo glutamate/GABA ratio correlates with the social behavior deficit in a mouse model of autism spectrum disorder	13
Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates	13
Adult neurogenesis mediates forgetting of multiple types of memory in the rat	13
In vivo imaging of immediate early gene expression dynamics segregates neuronal ensemble of memories of dual events	13
New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissue	13
A CACNA1A variant associated with trigeminal neuralgia alters the gating of Cav2.1 channels	13
Brain region networks for the assimilation of new associative memory into a schema	13

Distinct role of 5′UTR sequences in dendritic trafficking of BDNF mRNA: additional mechanisms for the BDNF splice variants spatial code	13
Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice	13
Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation	12
Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice	12
Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in	12
Altered striatal dopamine levels in Parkinson’s disease VPS35 D620N mutant transgenic aged mice	12
Minhee Analysis Package: an integrated software package for detection and management of spontaneous synaptic events	12
Conditional knock out of transcription factor CTCF in excitatory neurons induces cognitive deficiency	12
iTRAQ-based proteomic profiling reveals protein alterations after traumatic brain injury and supports thyroxine as a potential treatment	12
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo	12
Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus	12
Integrin β3 organizes dendritic complexity of cerebral cortical pyramidal neurons along a tangential gradient	12
Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice	12
Knee osteoarthritis accelerates amyloid beta deposition and neurodegeneration in a mouse model of Alzheimer’s disease	12
MeCP2 gates spatial learning-induced alternative splicing events in the mouse hippocampus	12
The de novo CACNA1A pathogenic variant Y1384C associated with hemiplegic migraine, early onset cerebellar atrophy and developmental delay leads to a loss of Cav2.1 channel function	12
Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)	11
Increased ribosomal protein levels and protein synthesis in the striatal synaptosome of Shank3-overexpressing transgenic mice	11
Cirbp-PSD95 axis protects against hypobaric hypoxia-induced aberrant morphology of hippocampal dendritic spines and cognitive deficits	11
Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition	11
The increased in vivo firing of pyramidal cells but not interneurons in the anterior cingulate cortex after neuropathic pain	11
Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down’s syndrome mouse model	11
Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain	11
Serotonergic gene-to-gene interaction is associated with mood and GABA concentrations but not with pain-related cerebral processing in fibromyalgia subjects and healthy controls	11
Enhanced contextual fear memory in peroxiredoxin 6 knockout mice is associated with hyperactivation of MAPK signaling pathway	11
VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder	10
Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice	10
Neuregulin-1 inhibits CoCl2-induced upregulation of excitatory amino acid carrier 1 expression and oxidative stress in SH-SY5Y cells and the hippocampus of mice	10
Changes in oligodendroglial subpopulations in Parkinson’s disease	10
Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells	10
Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice	10
Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice	10
Antiallodynic effects of KDS2010, a novel MAO-B inhibitor, via ROS-GABA inhibitory transmission in a paclitaxel-induced tactile hypersensitivity model	10
Dihydroartemisinin attenuates hypoxic-ischemic brain damage in neonatal rats by inhibiting oxidative stress	10
FMRP attenuates activity dependent modifications in the mitochondrial proteome	10
Overexpression of LIMK1 in hippocampal excitatory neurons improves synaptic plasticity and social recognition memory in APP/PS1 mice	10
Profile of dorsal root ganglion neurons: study of oxytocin expression	9
Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases	9
Rapid generation of conditional knockout mice using the CRISPR-Cas9 system and electroporation for neuroscience research	9
Multivalent electrostatic pi–cation interaction between synaptophysin and synapsin is responsible for the coacervation	9
Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis	9
NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice	9
Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis	9
Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity	9
Neuronal activity regulates alternative exon usage	9
Transcriptomic profiling of sporadic Alzheimer’s disease patients	9
Functional identification of potential non-canonical N-glycosylation sites within Cav3.2 T-type calcium channels	9
Postsynaptic structure formation of human iPS cell-derived neurons takes longer than presynaptic formation during neural differentiation in vitro	9
Cannabinoid receptors distribution in mouse cortical plasma membrane compartments	9
Retina-attached slice recording reveals light-triggered tonic GABA signaling in suprachiasmatic nucleus	9
Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons	9
Similarities of developmental gene expression changes in the brain between human and experimental animals: rhesus monkey, mouse, Zebrafish, and Drosophila	9
Activity of putative orexin neurons during cataplexy	9
Overexpression of astroglial major histocompatibility complex class I in the medial prefrontal cortex impairs visual discrimination learning in mice	9
Cortical pain induced by optogenetic cortical spreading depression: from whole brain activity mapping	9
Meningitic Escherichia coli α-hemolysin aggravates blood–brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling	9
Optogenetic inhibition of medial entorhinal cortex inputs to the hippocampus during a short period of time right after learning disrupts contextual fear memory formation	9