OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Brain is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons	166
Protocadherin 19 regulates axon guidance in the developing Xenopus retinotectal pathway	84
FMRP binds Per1 mRNA and downregulates its protein expression in mice	56
Correction to: Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity	48
Spatiotemporal Pavlovian head-fixed reversal learning task for mice	47
Diurnal variation in declarative memory and the involvement of SCOP in cognitive functions in nonhuman primates	44
A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy	38
Inhibition of cortical synaptic transmission, behavioral nociceptive, and anxiodepressive-like responses by arecoline in adult mice	37
Chronic corticosterone exposure causes anxiety- and depression-related behaviors with altered gut microbial and brain metabolomic profiles in adult male C57BL/6J mice	36
Knockout of AMPA receptor binding protein Neuron-specific gene 2 (NSG2) enhances associative learning and cognitive flexibility	36
Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson’s disease pathogenesis	32
Recent developments in peptide vaccines against Glioblastoma, a review and update	31
Npas4 regulates synaptic development in the patch/striosome compartment and early affective vocalization in neonatal mice	30
Chronic oral administration of ibrutinib prevents long-term memory deficits and reduces AD pathology and neuroinflammatory responses in a mouse model of AD	29
Impact of volume and expression time in an AAV-delivered channelrhodopsin	28
Upregulation of TRPV2 exacerbates age-related hearing loss by promoting oxidative stress in spiral ganglion neurons	28
m6A RNA methylation in neural plasticity, brain aging, and neurodegenerative vulnerability	24
Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging	24
Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice	22
Correction: The deficiency of Maged1 attenuates Parkinson’s disease progression in mice	21
Correction to: Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	21
AKAP6 controls NFATc4 activity for BDNF-mediated neuroprotection	20
Chronic stress increases the susceptibility to chronic vulvar pain following acute vulvar inflammation in a preclinical model of vulvodynia	20
The brain cytokine orchestra in multiple sclerosis: from neuroinflammation to synaptopathology	20
Role of autophagy in neurotoxic protein’s clearance following post-ischemic stroke: where we are and what we know?	19

Zinc-mediated lysosomal activation by 1H10 enhances autophagy and attenuates tau pathology in Alzheimer’s disease models	18
Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H	18
A simple and reliable method for claustrum localization across age in mice	18
Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications	18
Involvement of posterior hypothalamic CaMKII-positive neurons in ADHD-like behaviors in mice	17
Novelty-induced memory consolidation is accompanied by increased Agap3 transcription: a cross-species study	17
Diabetes reprograms brain and systemic immune landscapes to impair repair after injury	16
The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels	16
Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export	16
Chemogenetic activation of histamine neurons promotes retrieval of apparently lost memories	16
Selective enhancement of fear extinction by inhibiting neuronal adenylyl cyclase 1 (AC1) in aged mice	16
Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction	16
MeCP2 deficiency impairs motor cortical circuit flexibility associated with motor learning	15
Organoids as next-generation models for investigating intracranial tumours	15
Chronic pain enhances excitability of corticotropin-releasing factor-expressing neurons in the oval part of the bed nucleus of the stria terminalis	14
Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study	14
Reduced activity of parvalbumin-positive interneurons in the posterior parietal cortex causes visually dominant multisensory decisions in freely navigating mice	14
Intravitreal injection of the Galectin-3 inhibitor TD139 provides neuroprotection in a rat model of ocular hypertensive glaucoma	14
Increased social interaction in Shank2-deficient mice following acute social isolation	14
Unaltered empathy-related behaviors in Williams–Beuren syndrome mouse models	13
Neurexin-3 in the paraventricular nucleus of the hypothalamus regulates body weight and glucose homeostasis independently of food intake	13
Pathophysiology of ion channels in amyotrophic lateral sclerosis	13
A new paradigm of learned cooperation reveals extensive social coordination and specific cortical activation in mice	13
Chronic skin ultraviolet irradiation induces transcriptomic changes associated with microglial dysfunction in the hippocampus	13
The gut microbiota and metabolite profiles are altered in patients with spinal cord injury	13
Novelty triggers time-dependent theta oscillatory dynamics in cortical-hippocampal-midbrain circuitry	12
TREM2 improves microglia function and synaptic development in autism spectrum disorders by regulating P38 MAPK signaling pathway	12
Toll-like receptors and their role in neuropathic pain and migraine	12
Sonication dissociates the synaptic cleft and allows purification of postsynaptic densities with associated postsynaptic membrane	12
Mycophenolate mofetil reduces the branching of microglial processes	12
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD	12
Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice – a model-free multivariate analysis	12
Spermidine treatment: induction of autophagy but also apoptosis?	12
Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity	11
Repeated naloxone-induced morphine withdrawal alters blood brain barrier and blood spinal cord barrier integrity in mice	11
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state	11
NEK7 induces lactylation in Alzheimer’s disease to promote pyroptosis in BV-2 cells	11
Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice	11
Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy	11
Artificial intelligence-based biomarkers for the diagnosis and treatment of neurological conditions: a narrative review	11
Changes in oligodendroglial subpopulations in Parkinson’s disease	11
Elucidation of the mechanisms underlying tumor aggravation by the activation of stress-related neurons in the paraventricular nucleus of the hypothalamus	11
Analysis of neurexin-neuroligin complexes supports an isoform-specific role for beta-neurexin-1 dysfunction in a mouse model of autism	10
A new AAV tool for highly preferentially targeting hippocampal CA2	10
AldoC BAC-GFP transgenic mice as a reliable model for astrocyte identification and functional studies in the brain	10
Nek6 regulates autophagy through the mTOR signaling pathway to alleviate cerebral ischemia–reperfusion injury	10
Aging-independent decrease of complex multi-spine boutons in hippocampal area CA1 after contextual fear conditioning	10
Crucial role of TFAP2B in the nervous system for regulating NREM sleep	10
Generation of a new Slc20a2 knockout mouse line as in vivo model for primary brain calcification	10
Correction: Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	9

Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice	9
Acupuncture improves depressive-like behaviors in CUMS rats by modulating lateral habenula synaptic plasticity via the BDNF/ERK/mTOR pathway	9
Astrocytic activation increases blood flow in the adult olfactory bulb	9
Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice	9
Proteomic analysis of transcutaneous auricular vagus nerve stimulation induced cognitive restoration in a mouse model of vascular cognitive impairment	9
Correction: Requirement for hippocampal CA3 NMDA receptors in artificial association of memory events stored in CA3 cell ensembles	9
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease	9
Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism	9
Outer layer of Vb neurons in medial entorhinal cortex project to hippocampal dentate gyrus in mice	8
Human midbrain organoids reveal the characteristics of axonal mitochondria specific to dopaminergic neurons	8
Experience-dependent changes in affective valence of taste in male mice	8
Peripheral-central network analysis of cancer cachexia status accompanied by the polarization of hypothalamic microglia with low expression of inhibitory immune checkpoint receptors	8
The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice	8
The medial prefrontal cortex encodes procedural rules as sequential neuronal activity dynamics	8
Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation	8
Central nervous system pericytes express soluble ST2 in inflammation and injury	8
Hypothalamic protein profiling from mice subjected to social defeat stress	8
Deleting IP6K1 stabilizes neuronal sodium–potassium pumps and suppresses excitability	8
Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila	8
Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	8
PV-IRES-Cre mouse line targets excitatory granule neurons in the cerebellum	8