OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Brain is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Diurnal variation in declarative memory and the involvement of SCOP in cognitive functions in nonhuman primates	63
Knockout of AMPA receptor binding protein Neuron-specific gene 2 (NSG2) enhances associative learning and cognitive flexibility	51
FMRP binds Per1 mRNA and downregulates its protein expression in mice	41
Spatiotemporal Pavlovian head-fixed reversal learning task for mice	41
Protocadherin 19 regulates axon guidance in the developing Xenopus retinotectal pathway	39
Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson’s disease pathogenesis	39
Correction to: Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	35
Correction to: Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity	33
mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons	33
Inhibition of cortical synaptic transmission, behavioral nociceptive, and anxiodepressive-like responses by arecoline in adult mice	33
New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissue	30
The parabrachial-to-amygdala pathway provides aversive information to induce avoidance behavior in mice	29
Chronic corticosterone exposure causes anxiety- and depression-related behaviors with altered gut microbial and brain metabolomic profiles in adult male C57BL/6J mice	29
A simple and reliable method for claustrum localization across age in mice	28
A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy	28
Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration	27
Aversive emotion rapidly activates orexin neurons and increases heart rate in freely moving mice	26
Impact of volume and expression time in an AAV-delivered channelrhodopsin	26
The brain cytokine orchestra in multiple sclerosis: from neuroinflammation to synaptopathology	26
Arginine vasopressin in the medial amygdala causes greater post-stress recruitment of hypothalamic vasopressin neurons	26
Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice	25
Optimization of protocols for pre-embedding immunogold electron microscopy of neurons in cell cultures and brains	24
Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging	23
Correction: The deficiency of Maged1 attenuates Parkinson’s disease progression in mice	23
AKAP6 controls NFATc4 activity for BDNF-mediated neuroprotection	22

Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation	22
Kdm3b haploinsufficiency impairs the consolidation of cerebellum-dependent motor memory in mice	21
Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H	21
Chemogenetic activation of histamine neurons promotes retrieval of apparently lost memories	21
Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications	21
Novelty-induced memory consolidation is accompanied by increased Agap3 transcription: a cross-species study	21
Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice	20
Cannabinoid receptors distribution in mouse cortical plasma membrane compartments	20
Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction	20
Chronic pain enhances excitability of corticotropin-releasing factor-expressing neurons in the oval part of the bed nucleus of the stria terminalis	20
Involvement of posterior hypothalamic CaMKII-positive neurons in ADHD-like behaviors in mice	20
VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder	19
Nanoscale organization of Nicastrin, the substrate receptor of the γ-secretase complex, as independent molecular domains	19
Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus	19
Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic traumatic encephalopathy in human samples	18
Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling	18
Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export	18
Selective enhancement of fear extinction by inhibiting neuronal adenylyl cyclase 1 (AC1) in aged mice	18
Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response	18
Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia	17
The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels	17
Impaired wakefulness and rapid eye movement sleep in dopamine-deficient mice	17
Reduced activity of parvalbumin-positive interneurons in the posterior parietal cortex causes visually dominant multisensory decisions in freely navigating mice	17
MeCP2 deficiency impairs motor cortical circuit flexibility associated with motor learning	16
Neurexin-3 in the paraventricular nucleus of the hypothalamus regulates body weight and glucose homeostasis independently of food intake	16
Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	16
Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study	16
A new paradigm of learned cooperation reveals extensive social coordination and specific cortical activation in mice	16
Intravitreal injection of the Galectin-3 inhibitor TD139 provides neuroprotection in a rat model of ocular hypertensive glaucoma	16
mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination	15
Pathophysiology of ion channels in amyotrophic lateral sclerosis	15
Increased social interaction in Shank2-deficient mice following acute social isolation	15
Correction to: Networked neural spheroid by neuro-bundle mimicking nervous system created by topology effect	15
Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory	15
The gut microbiota and metabolite profiles are altered in patients with spinal cord injury	15
A natural marmoset model of genetic generalized epilepsy	14
Changes in oligodendroglial subpopulations in Parkinson’s disease	14
Spermidine treatment: induction of autophagy but also apoptosis?	13
TREM2 improves microglia function and synaptic development in autism spectrum disorders by regulating P38 MAPK signaling pathway	13
Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice – a model-free multivariate analysis	13
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD	12
Chronic skin ultraviolet irradiation induces transcriptomic changes associated with microglial dysfunction in the hippocampus	12
Reversibility of motor dysfunction in the rat model of NGLY1 deficiency	12
Toll-like receptors and their role in neuropathic pain and migraine	12
Disruption of the astrocyte–neuron interaction is responsible for the impairments in learning and memory in 5XFAD mice: an Alzheimer’s disease animal model	12
Novelty triggers time-dependent theta oscillatory dynamics in cortical-hippocampal-midbrain circuitry	12
Selectively increasing GHS-R1a expression in dCA1 excitatory/inhibitory neurons have opposite effects on memory encoding	12
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression	12
Elucidation of the mechanisms underlying tumor aggravation by the activation of stress-related neurons in the paraventricular nucleus of the hypothalamus	11
Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases	11

Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice	11
NEK7 induces lactylation in Alzheimer’s disease to promote pyroptosis in BV-2 cells	11
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state	11
Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity	11
Correction: Requirement for hippocampal CA3 NMDA receptors in artificial association of memory events stored in CA3 cell ensembles	11
Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy	11
Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease	11
Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons	11
Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down’s syndrome mouse model	11
Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice	10
Splice-variant specific effects of a CACNA1H mutation associated with writer’s cramp	10
The adaptor protein PICK1 targets the sorting receptor SorLA	10
Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons	10
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease	10
Astrocytic activation increases blood flow in the adult olfactory bulb	10
A new AAV tool for highly preferentially targeting hippocampal CA2	10
Y-27632, a ROCK inhibitor, improved laser-induced shock wave (LISW)-induced cochlear synaptopathy in mice	10
Analysis of neurexin-neuroligin complexes supports an isoform-specific role for beta-neurexin-1 dysfunction in a mouse model of autism	10
Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice	9
Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis	9
Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila	9
Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation	9
Peripheral-central network analysis of cancer cachexia status accompanied by the polarization of hypothalamic microglia with low expression of inhibitory immune checkpoint receptors	9
Hypothalamic protein profiling from mice subjected to social defeat stress	9
Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice	9
Crucial role of TFAP2B in the nervous system for regulating NREM sleep	9
Nek6 regulates autophagy through the mTOR signaling pathway to alleviate cerebral ischemia–reperfusion injury	9
PV-IRES-Cre mouse line targets excitatory granule neurons in the cerebellum	9
Inhibition of autophagy by CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR pathway contributes to ischemic postconditioning-induced neuroprotection against cerebral ischemia-reperfusion	9
Hypoxia with inflammation and reperfusion alters membrane resistance by dynamically regulating voltage-gated potassium channels in hippocampal CA1 neurons	9
Correction: Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	9
Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism	9
Experience-dependent changes in affective valence of taste in male mice	9
The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice	9
Acute social defeat stress activated neurons project to the claustrum and basolateral amygdala	9