OOIR: Observatory of International Research

Papers

(The TQCC of Cardiovascular Therapeutics is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Left Bundle Branch Area Pacing versus Right Ventricular Pacing in Patients with Atrioventricular Block: An Observational Cohort Study	89
Fibroblast Activation Protein‐Targeted CAR‐T Cells Induce Apoptosis in Murine Cardiac Myofibroblasts	53
Statin Eligibility according to 2013 ACC/AHA and USPSTF Guidelines among Jordanian Patients with Acute Myocardial Infarction: The Impact of Gender	42
L-Carnitine Alleviates the Myocardial Infarction and Left Ventricular Remodeling through Bax/Bcl-2 Signal Pathway	37
A Novel Intracardiac Echocardiography–Guided Approach for Vein of Marshall Ethanol Infusion in Persistent Atrial Fibrillation Ablation	36
Thrombospondin‐1 Silencing Ameliorates Osteoblastic Differentiation of Aortic Valve Interstitial Cells via Inhibiting Nuclear Factor‐ κ B Pathway	32
Thymidine Phosphorylase Promotes Abdominal Aortic Aneurysm via VSMC Modulation and Matrix Remodeling in Mice and Humans	25
Effect of Adiponectin Variant on Lipid Profile and Plasma Adiponectin Levels: A Multicenter Systematic Review and Meta-Analysis	24
Exploring Potential Drug Targets in Multiple Cardiovascular Diseases: A Study Based on Proteome‐Wide Mendelian Randomization and Colocalization Analysis	20
Role of K+ and Ca2+ Channels in the Vasodilator Effects of Plectranthus barbatus (Brazilian Boldo) in Hypertensive Rats	19
Assessment of Angiography‐Based Renal Quantitative Flow Ratio Measurement in Patients with Atherosclerotic Renal Artery Stenosis	17
The Application Value of Brain Natriuretic Peptide in the Prognostic Evaluation of Patients With Chronic Left Heart Failure	17
Efficacy and Safety of Olezarsen in Patients With Hypertriglyceridemia: A Meta‐Analysis of Randomized Controlled Trials	16
The Impact of the Metal Mixture Inflammation Index on All‐Cause Mortality in Patients With Cardiovascular‐Kidney‐Metabolic Syndrome Stages 0–3: A Study Based on NHANES 1999–2010	15
The Alteration of HDL in Patients with AMI Inhibited Angiogenesis by Blocking ERK1/2 Activation	15
Characteristics of Cardiac Ketone Body Metabolism Throughout the Life Cycle	15
Cysteine‐Rich Protein 61 (CCN1) Deficiency Alleviated Cardiac Remodeling in 5/6 Nephrectomized Mice by Suppressing the MAPK Signaling Pathway	15
A Multicohort Machine Learning Framework to Predict Mortality in Elderly Patients With Heart Disease: Insights From HARLS, SHARE, and HRS	14
MIR22HG Aggravates Oxygen-Glucose Deprivation and Reoxygenation-Induced Cardiomyocyte Injury through the miR-9-3p/SH2B3 Axis	13
Angiotensin Receptor–Neprilysin Inhibitor in Heart Failure Patients With Renal Dysfunction	13
Recent Advances in Renal Denervation Therapy and Novel Applications of High‐Intensity Focused Ultrasound	13
The Efficacy and Safety of Four Novel PCSK9 Monoclonal Antibodies in Patients With Hypercholesterolemia: A Systematic Review With Network Meta‐Analysis and Trial Sequential Analysis	12
Subclinical Hypothyroidism as a Risk for Coronary Artery Bypass Grafting	12
Effect of TRIB1 Variant on Lipid Profile and Coronary Artery Disease: A Systematic Review and Meta-Analysis	11
The Effect of Clinically Indicated Liraglutide on Pericoronary Adipose Tissue in Type 2 Diabetic Patients	11

The Bioprotective Effects of Marigold Tea Polyphenols on Obesity and Oxidative Stress Biomarkers in High‐Fat‐Sugar Diet‐Fed Rats	11
Inhibitory Effect of Lactobacillus delbrueckii subsp. bulgaricus KSFY07 on Kappa-Carrageenan-Induced Thrombosis in Mice and the Regulation of Oxidative Damage	11
Heart Failure with Preserved Left Ventricular Ejection Fraction: A Complex Conundrum Simply Not Limited to Diastolic Dysfunction	11
Metformin Attenuates Myocardial Ischemia–Reperfusion Injury in Rats by Modulating JNK Pathway and Inhibiting PANoptosis Mechanisms	11
Effect of Thrombolysis on Circulating Microparticles in Patients with ST-Segment Elevation Myocardial Infarction	11
Knockdown of lncRNA XIST Ameliorates IL-1β-Induced Apoptosis of HUVECs and Change of Tissue Factor Level via miR-103a-3p/HMGB1 Axis in Deep Venous Thrombosis by Regulating the ROS/NF-κB Signaling Path	10
The Effect of Vasopressin on 90‐Day Mortality in Patients With Cardiogenic Shock: A Retrospective Cohort Study Using Propensity Score‐Weighted Analysis	10
IL6/IL10/TLR4 Govern Immunogenic Cell Death in Aortic Dissection	10
Antiatherogenic and Cardioprotective Effects of a Xanthine Derivative KMUP‐1 in ApoE Knockout Mice	9
Knockdown of LncRNA CCAT1 Attenuates ox‐LDL‐Induced Inflammation in THP1‐Derived Macrophages via the miR‐296‐3p/FOSL1 Axis	9
Electrocardiogram Parameters That Affect the Success Rate of Radiofrequency Ablation in Patients with Outflow Tract Ventricular Premature Complexes	9
A Retrospective Cross‐Sectional Study on the Clinicopathologic Features of Essential Hypertension at High Altitude in China	9
Liquid Embolization of Peripheral Arteriovenous Malformations with Ethylene-Vinyl Alcohol Copolymer in Neonates and Infants	9
“RotaTripsy” as State‐of‐the‐Art Strategy for Coronary Artery Calcification: A Scoping Review	9
DT-010 Exerts Cardioprotective Effects by Regulating the Crosstalk between the AMPK/PGC-1α Pathway and ERp57	9
Integrating Traditional Wisdom With Modern Science: Ginsenosides as Antiheart Failure Agents	8
The Regulation Network of Glycerolipid Metabolism as Coregulators of Immunotherapy-Related Myocarditis	8
Identification of Potential Biomarkers for Coronary Artery Disease Based on Cuproptosis	8
Association Between Albumin‐Corrected Anion Gap and Mortality in ICU Patients With Acute Heart Failure: A MIMIC‐IV Cohort Study	8
The Impact of SGLT2 Inhibitors on Pulmonary Artery Pressures and Pulmonary Hemodynamics in Patients With Heart Failure: A Systematic Review	7
The Effect of Stress Ball on Anxiety and Pain Levels in Angiography: A Randomized Controlled Trial	7
Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi	7
Water-Based Exercises on Peak Oxygen Consumption, Exercise Time, and Muscle Strength in Patients with Coronary Artery Disease: A Systematic Review with Meta-Analysis	7
Hemodynamic Variability in Aortic Stenosis and Regurgitation During Transcatheter Aortic Valve Replacement With Self‐Expanding Valves	7
Verteporfin Mitigates Isoproterenol‐Induced Myocardial Hypertrophy by Attenuating IL‐6/STAT3 in Cardiac Fibroblasts	7
Perioperative Treatment with Rivaroxaban and Dabigatran on Changes of Coagulation and Platelet Activation Biomarkers following Left Atrial Appendage Closure	6
Metabolic Profiling Reveals Diagnostic Biomarkers for Distinguishing Myocarditis From Acute Myocardial Infarction	6
Effectiveness and Safety of Shengmai San for Viral Myocarditis: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials	6
Safety and Feasibility of a Novel Split Design Left Atrial Appendage Occluder: From Preclinical Investigations to First‐in‐Human Application	6
Atrial Fibrillation Termination as a Predictor for Persistent Atrial Fibrillation Ablation: A Systemic Review and Meta‐Analysis of Prospective Studies	6
Association of Choline Intake with Blood Pressure and Effects of Its Microbiota-Dependent Metabolite Trimethylamine-N-Oxide on Hypertension	6
Role of Macrophage Phagocytosis as Predictive Marker of the Prevalence of Coronary Heart Disease and Acute Coronary Syndromes	6
Analysis of the Efficacy and Safety of Coronary Catheterization through Distal Transradial Access: A Single-Center Data	6
NHANES‐Derived Machine Learning Model for Early Identification of Frailty Risk in CKM: Optimizing Resource Allocation Through Predictive Analytics	6
Low‐Dose Mavacamten Initiation in Obstructive Hypertrophic Cardiomyopathy: A Real‐World Study in China	6