Nature Chemistry

Article	Citations
Not all catenanes with oriented rings are topologically chiral	450
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	355
General strategy for the synthesis of N-monofluoromethyl amides	319
Supramolecular crystals for hydrogen storage	265
DNA catch bonds demonstrate the art of getting stuck	260
Using symmetry to drive new protein assemblies	209
Pop-up rings to rule reactivity	204
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	197
Corrole and squeezed coordination	192
Understanding single-molecule reactions using nanopore-based techniques	181
Tunable valence tautomerism in lanthanide–organic alloys	176
The numerous paths of ferrocene	173
Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells	158
Baird’s rules at the tipping point	154
Metal-hydroxyls mediate intramolecular proton transfer in heterogeneous O–O bond formation	154
A near-linear lanthanide complex that displays magnet-like behaviour	147
Zigzag graphene nanoribbons with periodic porphyrin edge extensions	145
Building enzymes from scratch	144
Protons undermine lithium-ion batteries with positively disastrous results	143
Eric the AI research assistant for chemists	138
Sulfone cross-coupling outcompetes proton transfer	138
Function without form in synthetic polymers mimicking protein hydration	137
Leveraging relaxation-optimized 1H–13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins	136
A soil-inspired dynamically responsive chemical system for microbial modulation	135
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	135

Enantiospecific cross-coupling of cyclic alkyl sulfones	131
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	130
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	129
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	128
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	127
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	127
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	127
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	126
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	126
O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95	125
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	125
Reversible self-assembly of small molecules for recyclable solid-state battery electrolytes	123
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	122
A metalloenzyme platform for catalytic asymmetric radical dearomatization	121
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	121
Digital skills in chemical education	120
Single crystals of purely organic free-standing two-dimensional woven polymer networks	120
Iron–sulfur clusters as inhibitors and catalysts of viral replication	120
Photomediated aliphatic C–H functionalization	119
Charging imide anions for batteries	119
Beyond Hubble	118
Bottleable triplet nitrenes	118
A programmable biomimetic cytoskeleton	114
New-to-nature biocompatible chemistry for plastic waste upcycling	114
A template for artificial life	113
Aryl ortho methoxylation	110
ATP hydrolysis captured in atomic detail	109
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	109
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	108
D3+ formation through photoionization of the molecular D2–D2 dimer	108
Tetrafunctional cyclobutanes tune toughness via network strand continuity	108
Multilayer stacks of polycyclic aromatic hydrocarbons	105
Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes	104
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	104
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	103
An electroaffinity labelling platform for chemoproteomic-based target identification	103
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	103
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	102
Excitation energy transfer and vibronic coherence in intact phycobilisomes	102
Aromaticity rules	100
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	99
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	99
Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	99
Constructing artificial gap junctions to mediate intercellular signal and mass transport	97
Homogeneous multi-payload antibody–drug conjugates	96
Insights from an information thermodynamics analysis of a synthetic molecular motor	96
Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	95
Optical sequencing of single synthetic polymers	95
Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues	95
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	94

Heterogeneous polymer designs that bring electricity, light and substrates together	93
Challenges to developing materials for the transport and storage of hydrogen	93
Bridging aqueous electrochemistry and non-aqueous chemistry for chemical production	92
Pluralistic teaching	91
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	91
A dynamic metal–organic framework photocatalyst	91
Covalent organic frameworks as infinite building units for metal–organic frameworks with compartmentalized pores	90
Leveraging electron donor–acceptor complexes for kinetic resolution in catalytic asymmetric photochemical synthesis	89
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	89
4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	89
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	88
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	88
Milking riboflavin for all it’s worth	87
Three-dimensional van der Waals open frameworks	86
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	86
Sustainable and degradable plastics	86
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	86
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	85
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	85
Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	85
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	84
Photoswitchable coordination cages	84
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	84
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	83
In vivo metallophilic self-assembly of a light-activated anticancer drug	83
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry	83
An open-shell molecule that exhibits conformational dynamics	83
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	82
Transient water wires mediate selective proton transport in designed channel proteins	82
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	81
Working towards a new job	80
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	79
CO2 sorption in fluorinated non-porous coordination polymers	78
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	77
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	77
Anticancer platinum-based photo-oxidants in a new light	76
Strong dipole-promoted N–O bond hydrogenolysis enables ampere-level electrosynthesis of methylamine	76
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	76
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	75
Lattice O–O ligands in Fe-incorporated hydroxides enhance water oxidation electrocatalysis	75
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	74
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	74
An isolable germylyne radical with a one-coordinate germanium atom	74
Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells	74
Something new under the sun	73
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	73
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	73
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	73
Non-statistical assembly of multicomponent [Pd2ABCD] cages	72
Thickness control of organic semiconductor-incorporated perovskites	72
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	72
The impact of UV light on synthetic photochemistry and photocatalysis	72
Triplet metallocarbenes featuring carbon-centred spin localization	71
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	71
Engineered RNA sensors for tuberculosis detection	71
Cooperative ligands enable cobalt-catalysed hydrogenation	70
Publisher Correction: Porous covalent organic nanotubes and their assembly in loops and toroids	70
Heart of glass	70
A third strand for protein–DNA interactions	70
Isolation of halogen-substituted silylium ions	70
How polymers dance to the pulses of ultrasound	69
Looking into luciferin	69
Chiral control of spin-crossover dynamics in Fe(II) complexes	68
Checking out metal cluster chemistry from living libraries	68
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	68
Future-proofing calcium fluoride	68
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	68
Upcycling chlorinated trash into synthetic organic treasure	68
Amino amide assembly	67
A crystalline stannyne	67
Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways	67
Total synthesis of nine longiborneol sesquiterpenoids using a functionalized camphor strategy	67
Masked alkynes for synthesis of threaded carbon chains	67
Multi-compartment liposomes forge new paths in drug delivery	67
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	66
Janus-type emission from a cyclometalated iron(iii) complex	66
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	64
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	64
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	63
Quantum simulation of conical intersections using trapped ions	63

Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	63
Scalable and selective deuteration of (hetero)arenes	63
The importance of community as a pre-tenure faculty member	62
Sensing RNA	62
Positive climate changes	62
Asymmetric construction of sulfur(VI)–fluorine cores	61
Establishing the fundamental rules for genetic code expansion	61
Cyclopropenium functionalization	60
Mimicking the structure and function of tau folds associated with disease	60
A lithium–aluminium heterobimetallic dimetallocene	60
Electric field maps in enzymes	59
A bismuth-based analogue of the π-allyl cation	59
On gene silencing by the X10-23 DNAzyme	59
Copper-catalysed asymmetric cross-coupling reactions tolerant of highly reactive radicals	58
Ribose at the heart of life	58
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	57
Enantioconvergent radical addition of racemic alkyl halides to access vicinal stereocentres	57
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	57
Non-enzymatic methylcyclization of alkenes	56
Olefin π-coordination chemistry at low-oxidation-state boron	56
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	55
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	55
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	55
Exciton annihilation in molecular aggregates suppressed through quantum interference	54
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	54
A terminal neptunium(V)–mono(oxo) complex	53
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	53
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	53
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	53
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	53
Structure-specific amyloid precipitation in biofluids	52
Programmable fluorescent aptamer-based RNA switches for rapid identification of point mutations	52
Encoding signal propagation on topology-programmed DNA origami	52
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	52
Polymer connectivity governs electrophotocatalytic activity in the solid state	52
ChatGPT saves the day	52
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	52
Chemical testing	52
Rings of power	51
Doing away with radium’s proxies	51
How many roads must a woman walk down?	51
A molecular sandwich with a lithium–aluminium filling	51
Interweaving different metal–organic frameworks	51
Flexible interaction patches lead to building blocks with fluctuating valency	50
Reducing the carbon footprint of chemistry labs	50
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	50
Author Correction: Moiré two-dimensional covalent organic framework superlattices	50
Stereoselective alkylation of saturated heterocycles	50
Author Correction: Introducing metal–sulfur active sites in metal–organic frameworks via post-synthetic modification for hydrogenation catalysis	50
Colouring by force	49
Ion-pair reorganization regulates reactivity in photoredox catalysts	49
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	49
Hydrogenative double-bond deuteration	49
Heteromultivalency enables enhanced detection of nucleic acid mutations	49
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	49
A para- to meta-isomerization of phenols	49
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	49
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	49
Isolation and characterization of a two-coordinate phosphinidene oxide	49
Direct conversion of white phosphorus to versatile phosphorus transfer reagents via oxidative onioation	48
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	48
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	48
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	48
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	48
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	47
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	47
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	47
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	47
Building ultramicroporous zirconium metal‒organic frameworks with ligands of high coordination density through a reticular approach	47
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	47
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	46
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	46
Decarboxylative cross-nucleophile coupling via ligand-to-metal charge transfer photoexcitation of Cu(ii) carboxylates	46
Synthesis of highly strained para-cyclophanes via ring-expansion [5,5]-sigmatropic rearrangement reaction	46
Publisher Correction: OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues	46
From geranium lakes to catalysis with light	46
Intramolecular alkene and functional group translocation	45
Recyclable plastics from a manganese catalyst	45
An unnatural base pair for the detection of epigenetic cytosine modifications in DNA	45
WT19F	45
Selective arylation of atypical C–F bonds in polyfluoroarenes with aryl chlorides	45
Copper catalysed asymmetric amination	45
Critical race theory and its relevance for chemistry	45
Icing a three-layer cake for predictive modelling of adsorption	45
Quinine fever	44
Controlling anisotropic properties by manipulating the orientation of chiral small molecules	44
Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single-molecule pump–probe spectroscopy	43
Structure-informed design of an ultrabright RNA-activated fluorophore	43
Time-resolved terahertz–Raman spectroscopy reveals that cations and anions distinctly modify intermolecular interactions of water	43
Navigating protein landscapes with a machine-learned transferable coarse-grained model	43
Mirror-image trypsin digestion and sequencing of D-proteins	43
Progress and pitfalls in designing heterogeneous catalysts with molecular precision	42
Fused radical SAM and αKG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and β-hydroxylation	42
Iterative synthesis of 1,3-polyboronic esters with high stereocontrol and application to the synthesis of bahamaolide A	42
Carbonyl cross-metathesis via deoxygenative gem-di-metal catalysis	42