Nature Chemistry

Article	Citations
Not all catenanes with oriented rings are topologically chiral	487
General strategy for the synthesis of N-monofluoromethyl amides	299
Supramolecular crystals for hydrogen storage	280
DNA catch bonds demonstrate the art of getting stuck	245
Using symmetry to drive new protein assemblies	240
Pop-up rings to rule reactivity	223
A near-linear lanthanide complex that displays magnet-like behaviour	221
Protons undermine lithium-ion batteries with positively disastrous results	209
Corrole and squeezed coordination	192
Sulfone cross-coupling outcompetes proton transfer	185
Function without form in synthetic polymers mimicking protein hydration	184
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	183
A soil-inspired dynamically responsive chemical system for microbial modulation	180
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	177
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	174
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	173
Radical water opens parallel pathways in CO2 electrocatalysis	163
Bridged bicycloalkanes through thermal [2+2] cycloaddition	163
Enantiospecific cross-coupling of cyclic alkyl sulfones	161
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	160
A metalloenzyme platform for catalytic asymmetric radical dearomatization	159
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	158
Leveraging relaxation-optimized 1H–13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins	156
Eric the AI research assistant for chemists	150
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	148

Digital skills in chemical education	145
Baird’s rules at the tipping point	143
Tunable valence tautomerism in lanthanide–organic alloys	140
Controlling chromophore assembly and coupling via carbon nanohoops enables singlet fission at interchromophore distances up to 16 Å	140
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	140
Single crystals of purely organic free-standing two-dimensional woven polymer networks	139
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	139
Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells	137
Modular diastereoselective synthesis of hindered cyclobutane amino nitriles through triplet nitrene-mediated ring expansion	134
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	134
Global profiling of arginine reactivity and ligandability in the human proteome	133
Zigzag graphene nanoribbons with periodic porphyrin edge extensions	131
Charging imide anions for batteries	130
Chiral catalysis-driven rotary molecular motors	129
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	128
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	128
Understanding single-molecule reactions using nanopore-based techniques	125
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	123
The numerous paths of ferrocene	123
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	120
Metal-hydroxyls mediate intramolecular proton transfer in heterogeneous O–O bond formation	120
Reversible self-assembly of small molecules for recyclable solid-state battery electrolytes	119
Beyond Hubble	118
Protecting skins of Au–Cl can stabilize Au nanostructures	118
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	117
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	116
Heterogeneous polymer designs that bring electricity, light and substrates together	116
A dynamic metal–organic framework photocatalyst	116
Bridging aqueous electrochemistry and non-aqueous chemistry for chemical production	115
Biocompatible ligand balancing in transition metal coordination enables benign in-cell protein arylation	114
A programmable biomimetic cytoskeleton	113
Photomediated aliphatic C–H functionalization	111
Aryl ortho methoxylation	111
A template for artificial life	111
Bottleable triplet nitrenes	105
A comprehensive model for the electric double layer of stepped platinum electrodes	103
D3+ formation through photoionization of the molecular D2–D2 dimer	103
New-to-nature biocompatible chemistry for plastic waste upcycling	103
ATP hydrolysis captured in atomic detail	103
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	102
Optical sequencing of single synthetic polymers	102
Single-crystal to single-crystal editing of metal–organic frameworks via ligand removal	100
Homogeneous multi-payload antibody–drug conjugates	99
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	99
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	98
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	98
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	97
Programming stacking order in conducting van der Waals metal–organic frameworks through ligand aggregation	97
Constructing artificial gap junctions to mediate intercellular signal and mass transport	96
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	96

Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	95
A synthetic cell microreactor with two types of interacting dynamic DNA-based pores	95
Challenges to developing materials for the transport and storage of hydrogen	94
Tetrafunctional cyclobutanes tune toughness via network strand continuity	94
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	94
Formal Diels–Alder reaction of saturated carboxylic acids via C–H activation	94
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	94
Superspreading and ultra-infiltrative coacervate mediates strong underwater adhesion on hydrated and lipidic substrates	93
Excitation energy transfer and vibronic coherence in intact phycobilisomes	93
Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	93
An electroaffinity labelling platform for chemoproteomic-based target identification	93
Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues	93
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	92
Pluralistic teaching	92
Two roads to lithium nucleation	91
Milking riboflavin for all it’s worth	91
An open-shell molecule that exhibits conformational dynamics	91
Generating extended foldamer dye stacks and unravelling their evolving exciton dynamics	91
Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	90
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	89
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	89
Transient water wires mediate selective proton transport in designed channel proteins	88
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	88
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	86
Discovering nickel enzymes within the aldo-keto reductase superfamily	85
Inverted metal-free active template synthesis of rotaxanes via axle‑mediated macrocyclization	85
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry	85
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	84
Photoswitchable coordination cages	84
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	83
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	82
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	82
In vivo metallophilic self-assembly of a light-activated anticancer drug	81
Covalent organic frameworks as infinite building units for metal–organic frameworks with compartmentalized pores	81
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	81
Three-dimensional van der Waals open frameworks	80
Emergence of specific binding and catalysis from a designed generalist binding protein	80
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	80
4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	79
Leveraging electron donor–acceptor complexes for kinetic resolution in catalytic asymmetric photochemical synthesis	79
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	79
Engineered RNA sensors for tuberculosis detection	77
Working towards a new job	77
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	76
Strong dipole-promoted N–O bond hydrogenolysis enables ampere-level electrosynthesis of methylamine	76
Construction of synthetic protein-binding non-genetic DNA systems in living cells	76
Iridium(III)-catalysed ionic hydrogenation of pyridines to multisubstituted piperidines	75
Anticancer platinum-based photo-oxidants in a new light	75
Thickness control of organic semiconductor-incorporated perovskites	75
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	74
Something new under the sun	73
CO2 sorption in fluorinated non-porous coordination polymers	73
An isolable germylyne radical with a one-coordinate germanium atom	73
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	73
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	72
Unravelling gas evolution mechanisms in battery electrode materials	72
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	72
Isolated and H2-reduced Anderson clusters catalyse low-temperature hydrogenation of CO2 to methanol	71
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	71
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	71
Supramolecular assembly of molecular wires alternating crown ethers and metal–halide complexes	69
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	69
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	69
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	68
The impact of UV light on synthetic photochemistry and photocatalysis	68
Non-statistical assembly of multicomponent [Pd2ABCD] cages	68
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	68
Photoswitchable latent monomers enable on‑demand metathesis	67
A third strand for protein–DNA interactions	67
Lattice O–O ligands in Fe-incorporated hydroxides enhance water oxidation electrocatalysis	67
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	67
Heart of glass	66
Future-proofing calcium fluoride	66
Amino amide assembly	66
Looking into luciferin	66
Checking out metal cluster chemistry from living libraries	65
Sensing RNA	65
Cooperative ligands enable cobalt-catalysed hydrogenation	64
A crystalline stannyne	64
Upcycling chlorinated trash into synthetic organic treasure	63

Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways	63
Masked alkynes for synthesis of threaded carbon chains	63
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	62
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	62
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	62
Triplet metallocarbenes featuring carbon-centred spin localization	62
How polymers dance to the pulses of ultrasound	62
Janus-type emission from a cyclometalated iron(iii) complex	62
Single-crystalline two-dimensional vinylene frameworks through topological conversion	62
Multi-compartment liposomes forge new paths in drug delivery	61
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	61
Quantum simulation of conical intersections using trapped ions	61
Isolation of halogen-substituted silylium ions	61
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	61
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	60
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	60
Driving movement in the field of molecular machines	60
Organocatalytic enantioselective synthesis of S(IV)-stereogenic sulfinamides enabled by an air-stable chiral phosphine	59
Establishing the fundamental rules for genetic code expansion	59
The importance of community as a pre-tenure faculty member	59
Asymmetric construction of sulfur(VI)–fluorine cores	59
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	58
Mimicking the structure and function of tau folds associated with disease	58
Electric field maps in enzymes	58
Cyclopropenium functionalization	58
Ribose at the heart of life	58
A bismuth-based analogue of the π-allyl cation	57
ChatGPT saves the day	57
A stable, crystalline nitrogen chain radical	56
Enantioconvergent radical addition of racemic alkyl halides to access vicinal stereocentres	56
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	56
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	56
On gene silencing by the X10-23 DNAzyme	56
Polymer connectivity governs electrophotocatalytic activity in the solid state	56
Copper-catalysed asymmetric cross-coupling reactions tolerant of highly reactive radicals	56
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	55
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	55
Programmable fluorescent aptamer-based RNA switches for rapid identification of point mutations	55
Ligand-modulated metal–radical polarity match enables general 1,2-dicarbofunctionalization of ethylene	55
Structure-specific amyloid precipitation in biofluids	55
Encoding signal propagation on topology-programmed DNA origami	55
Author Correction: [2+2] Photocycloaddition reactions of sulfinylamines with alkenes to access β-sultam derivatives	54
Non-enzymatic methylcyclization of alkenes	54
A lithium–aluminium heterobimetallic dimetallocene	54
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	54
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	54
Olefin π-coordination chemistry at low-oxidation-state boron	54
Hydration entropy of cations regulates chloride ion diffusion during electrochemical chlorine evolution	53
Spontaneous trisulfide metathesis in polar aprotic solvents	53
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	53
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	53
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	52
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	51
Chemical recycling of hydrofluorocarbons by transfer fluorination	51
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	51
Exciton annihilation in molecular aggregates suppressed through quantum interference	51
Hyperpyramidalized alkenes with bond orders near 1.5 as synthetic building blocks	51
How many roads must a woman walk down?	49
A molecular sandwich with a lithium–aluminium filling	49
Rings of power	49
Author Correction: Moiré two-dimensional covalent organic framework superlattices	48
Flexible interaction patches lead to building blocks with fluctuating valency	48
Reducing the carbon footprint of chemistry labs	48
Stereoselective alkylation of saturated heterocycles	48
tRNA-deacylase-directed discovery of biosynthetic pathways	47
Colouring by force	47
Stannole dianions for axially coordinated lanthanide single-molecule magnets	47
Interweaving different metal–organic frameworks	47
Doing away with radium’s proxies	47
Hydrogenative double-bond deuteration	47
Author Correction: Introducing metal–sulfur active sites in metal–organic frameworks via post-synthetic modification for hydrogenation catalysis	47
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	46
Building ultramicroporous zirconium metal‒organic frameworks with ligands of high coordination density through a reticular approach	46
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	46
Heteromultivalency enables enhanced detection of nucleic acid mutations	46
A para- to meta-isomerization of phenols	45
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	45
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	45
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	45
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	45
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	45
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	45
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	45
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	44
Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-based proteolysis-targeting chimeras	44
Isolation and characterization of a two-coordinate phosphinidene oxide	44
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	44
An unnatural base pair for the detection of epigenetic cytosine modifications in DNA	43
Publisher Correction: OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues	43
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	43
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	43
Icing a three-layer cake for predictive modelling of adsorption	43
From geranium lakes to catalysis with light	43
Controlling anisotropic properties by manipulating the orientation of chiral small molecules	43
Intramolecular alkene and functional group translocation	43