Nature Chemistry

Article	Citations
Enantiospecific cross-coupling of cyclic alkyl sulfones	526
A near-linear lanthanide complex that displays magnet-like behaviour	378
Not all catenanes with oriented rings are topologically chiral	376
Eric the AI research assistant for chemists	338
General strategy for the synthesis of N-monofluoromethyl amides	325
Supramolecular crystals for hydrogen storage	246
Using symmetry to drive new protein assemblies	228
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	220
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	208
Pop-up rings to rule reactivity	205
The origin of translation	198
Digital skills in chemical education	196
DNA catch bonds demonstrate the art of getting stuck	187
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	180
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	174
Protons undermine lithium-ion batteries with positively disastrous results	171
Corrole and squeezed coordination	160
A metalloenzyme platform for catalytic asymmetric radical dearomatization	154
Building enzymes from scratch	149
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	147
Iron–sulfur clusters as inhibitors and catalysts of viral replication	145
Tunable valence tautomerism in lanthanide–organic alloys	145
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	142
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	138
The twists and turns of chiral chemistry	134

Single crystals of purely organic free-standing two-dimensional woven polymer networks	129
Baird’s rules at the tipping point	127
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	126
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	125
Platinum incorporation into titanate perovskites to deliver emergent active and stable platinum nanoparticles	123
A soil-inspired dynamically responsive chemical system for microbial modulation	122
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	120
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	119
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	119
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	118
Sulfone cross-coupling outcompetes proton transfer	118
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	116
SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome	114
O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95	113
The numerous paths of ferrocene	113
A programmable biomimetic cytoskeleton	112
Beyond Hubble	111
Photomediated aliphatic C–H functionalization	111
D3+ formation through photoionization of the molecular D2–D2 dimer	110
Adaptive response of a metal–organic framework through reversible disorder–disorder transitions	109
Optical sequencing of single synthetic polymers	109
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	109
Multilayer stacks of polycyclic aromatic hydrocarbons	108
A template for artificial life	107
ATP hydrolysis captured in atomic detail	106
Aryl ortho methoxylation	106
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	105
Combining biological and chemical diversity	104
Bottleable triplet nitrenes	102
Aromaticity rules	101
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	101
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	101
Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes	100
Homogeneous multi-payload antibody–drug conjugates	100
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	100
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	99
A catalytic asymmetric cross-coupling approach to the synthesis of cyclobutanes	98
A dynamic metal–organic framework photocatalyst	98
Insights from an information thermodynamics analysis of a synthetic molecular motor	97
Challenges to developing materials for the transport and storage of hydrogen	97
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	95
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	95
An electroaffinity labelling platform for chemoproteomic-based target identification	94
Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	93
Excitation energy transfer and vibronic coherence in intact phycobilisomes	93
Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	92
Pluralistic teaching	92
Constructing artificial gap junctions to mediate intercellular signal and mass transport	92
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	92
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	92

The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	92
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	90
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	88
Milking riboflavin for all it’s worth	87
4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	86
Three-dimensional van der Waals open frameworks	86
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	86
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	85
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	85
Sustainable and degradable plastics	85
Photoswitchable coordination cages	84
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	84
In vivo metallophilic self-assembly of a light-activated anticancer drug	84
Colloidal metallurgy	83
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	83
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	83
An open-shell molecule that exhibits conformational dynamics	81
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	81
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	81
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry	81
Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	80
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	80
Transient water wires mediate selective proton transport in designed channel proteins	80
Working towards a new job	79
Antimony cation acquired	77
Something new under the sun	76
The gains from breaking symmetry	74
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	73
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	73
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	73
Mastering mono-bond metathesis	73
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	72
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	72
Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells	72
Artificial, augmented and automated chemistry	72
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	72
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	72
An isolable germylyne radical with a one-coordinate germanium atom	72
Non-statistical assembly of multicomponent [Pd2ABCD] cages	71
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	71
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	71
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	70
A versatile approach for the synthesis of degradable polymers via controlled ring-opening metathesis copolymerization	70
The impact of UV light on synthetic photochemistry and photocatalysis	69
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	69
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	69
Anticancer platinum-based photo-oxidants in a new light	69
Integrating programmable DNAzymes with electrical readout for rapid and culture-free bacterial detection using a handheld platform	69
Thickness control of organic semiconductor-incorporated perovskites	68
Triplet metallocarbenes featuring carbon-centred spin localization	67
How polymers dance to the pulses of ultrasound	67
A third strand for protein–DNA interactions	67
Upcycling chlorinated trash into synthetic organic treasure	67
Multi-compartment liposomes forge new paths in drug delivery	67
Publisher Correction: Porous covalent organic nanotubes and their assembly in loops and toroids	67
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	66
Looking into luciferin	66
Amino amide assembly	66
A crystalline stannyne	66
Heart of glass	65
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	65
Total synthesis of nine longiborneol sesquiterpenoids using a functionalized camphor strategy	65
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	64
Isolation of a Ru(iv) side-on peroxo intermediate in the water oxidation reaction	64
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	64
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	63
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	63
Stoichiometric two-dimensional non-van der Waals AgCrS2 with superionic behaviour at room temperature	63
Checking out metal cluster chemistry from living libraries	63
Janus-type emission from a cyclometalated iron(iii) complex	62
Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways	62
Concurrent control over sequence and dispersity in multiblock copolymers	61
A proteome-wide atlas of lysine-reactive chemistry	61
Quantum simulation of conical intersections using trapped ions	61
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	61
Chiral control of spin-crossover dynamics in Fe(II) complexes	60
Masked alkynes for synthesis of threaded carbon chains	60
Manganese(i) complexes with metal-to-ligand charge transfer luminescence and photoreactivity	60
A ring expansion strategy towards diverse azaheterocycles	59
Scalable and selective deuteration of (hetero)arenes	59

ChatGPT saves the day	58
Establishing the fundamental rules for genetic code expansion	58
Non-enzymatic methylcyclization of alkenes	58
Asymmetric construction of sulfur(VI)–fluorine cores	58
Electric field maps in enzymes	58
The importance of community as a pre-tenure faculty member	58
Positive climate changes	58
A lithium–aluminium heterobimetallic dimetallocene	57
Cyclopropenium functionalization	57
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	57
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	56
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	55
Structure-specific amyloid precipitation in biofluids	55
Direct dynamic read-out of molecular chirality with autonomous enzyme-driven swimmers	55
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	54
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	54
A chiral interlocking auxiliary strategy for the synthesis of mechanically planar chiral rotaxanes	54
On gene silencing by the X10-23 DNAzyme	54
Exciton annihilation in molecular aggregates suppressed through quantum interference	54
Switching on prodrugs using radiotherapy	54
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	53
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	53
Encoding signal propagation on topology-programmed DNA origami	53
A terminal neptunium(V)–mono(oxo) complex	53
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	52
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	52
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	52
Bite-size science	51
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	51
How many roads must a woman walk down?	51
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	51
Best practices in machine learning for chemistry	51
Chemical testing	51
Accounts of academic ableism	50
Stereoselective alkylation of saturated heterocycles	50
Rings of power	50
Flexible interaction patches lead to building blocks with fluctuating valency	50
Ethics education for chemists	50
A molecular sandwich with a lithium–aluminium filling	49
Expanding the effectiveness of screening	49
Doing away with radium’s proxies	49
Interweaving different metal–organic frameworks	49
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	49
Hydrogenative double-bond deuteration	49
Heteromultivalency enables enhanced detection of nucleic acid mutations	48
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	48
Colouring by force	48
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	48
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	48
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	47
Decarboxylative cross-nucleophile coupling via ligand-to-metal charge transfer photoexcitation of Cu(ii) carboxylates	47
Tectonic shifts in framework chemistry	47
A para- to meta-isomerization of phenols	47
Dissipative DNA fibres	47
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	46
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	46
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	46
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	46
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	46
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	46
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	46
Isolation and characterization of a two-coordinate phosphinidene oxide	45
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	45
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	45
Ion-pair reorganization regulates reactivity in photoredox catalysts	45
Publisher Correction: OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues	44
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	44
Recyclable plastics from a manganese catalyst	44
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	44
The fruit fly of photophysics	44
Direct conversion of white phosphorus to versatile phosphorus transfer reagents via oxidative onioation	44
Progress and pitfalls in designing heterogeneous catalysts with molecular precision	43
Arenes participate in 1,3-dipolar cycloaddition with in situ-generated diazoalkenes	43
Modular enantioselective access to β-amino amides by Brønsted acid-catalysed multicomponent reactions	43
Copper catalysed asymmetric amination	42
Fused radical SAM and αKG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and β-hydroxylation	42
Time-resolved terahertz–Raman spectroscopy reveals that cations and anions distinctly modify intermolecular interactions of water	42
WT19F	42
Quinine fever	42
Tunable and recyclable polyesters from CO2 and butadiene	42
Emulsion-oriented assembly for Janus double-spherical mesoporous nanoparticles as biological logic gates	41
Carbonyl cross-metathesis via deoxygenative gem-di-metal catalysis	41
Molecular-docking electrolytes enable high-voltage lithium battery chemistries	41
Triarylmethyl cation redox mediators enhance Li–O2 battery discharge capacities	41
Critical race theory and its relevance for chemistry	41
Low-temperature liquid platinum catalyst	41
Mirror-image trypsin digestion and sequencing of D-proteins	41
Intramolecular alkene and functional group translocation	41
Tunable acetylene sorption by flexible catenated metal–organic frameworks	41
Halogen-bond-assisted radical activation of glycosyl donors enables mild and stereoconvergent 1,2-cis-glycosylation	40
Advances in single-molecule junctions as tools for chemical and biochemical analysis	40
Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein	40
Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single-molecule pump–probe spectroscopy	40
Iterative synthesis of 1,3-polyboronic esters with high stereocontrol and application to the synthesis of bahamaolide A	40
Enhanced active-site electric field accelerates enzyme catalysis	40