Nature Chemistry

Article	Citations
Not all catenanes with oriented rings are topologically chiral	495
General strategy for the synthesis of N-monofluoromethyl amides	305
Supramolecular crystals for hydrogen storage	291
DNA catch bonds demonstrate the art of getting stuck	247
Using symmetry to drive new protein assemblies	244
Pop-up rings to rule reactivity	233
A near-linear lanthanide complex that displays magnet-like behaviour	229
Protons undermine lithium-ion batteries with positively disastrous results	211
Corrole and squeezed coordination	199
Sulfone cross-coupling outcompetes proton transfer	193
Function without form in synthetic polymers mimicking protein hydration	189
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	188
A soil-inspired dynamically responsive chemical system for microbial modulation	187
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	185
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	179
Radical water opens parallel pathways in CO2 electrocatalysis	177
Bridged bicycloalkanes through thermal [2+2] cycloaddition	173
Enantiospecific cross-coupling of cyclic alkyl sulfones	168
Eric the AI research assistant for chemists	167
Digital skills in chemical education	166
The numerous paths of ferrocene	161
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	160
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	158
Reversible self-assembly of small molecules for recyclable solid-state battery electrolytes	157
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	150

Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	150
A metalloenzyme platform for catalytic asymmetric radical dearomatization	148
Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells	148
Leveraging relaxation-optimized 1H–13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins	144
Understanding single-molecule reactions using nanopore-based techniques	143
Single crystals of purely organic free-standing two-dimensional woven polymer networks	143
Zigzag graphene nanoribbons with periodic porphyrin edge extensions	140
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	137
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	137
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	133
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	133
Metal-hydroxyls mediate intramolecular proton transfer in heterogeneous O–O bond formation	131
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	131
Chiral catalysis-driven rotary molecular motors	130
Charging imide anions for batteries	130
Controlling chromophore assembly and coupling via carbon nanohoops enables singlet fission at interchromophore distances up to 16 Å	130
Modular diastereoselective synthesis of hindered cyclobutane amino nitriles through triplet nitrene-mediated ring expansion	128
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	128
Tunable valence tautomerism in lanthanide–organic alloys	126
Beyond Hubble	123
Global profiling of arginine reactivity and ligandability in the human proteome	123
Protecting skins of Au–Cl can stabilize Au nanostructures	122
A dynamic metal–organic framework photocatalyst	121
Heterogeneous polymer designs that bring electricity, light and substrates together	119
Bridging aqueous electrochemistry and non-aqueous chemistry for chemical production	118
A programmable biomimetic cytoskeleton	117
A template for artificial life	116
Aryl ortho methoxylation	114
Bottleable triplet nitrenes	113
ATP hydrolysis captured in atomic detail	109
Optical sequencing of single synthetic polymers	109
New-to-nature biocompatible chemistry for plastic waste upcycling	109
An electroaffinity labelling platform for chemoproteomic-based target identification	108
A synthetic cell microreactor with two types of interacting dynamic DNA-based pores	106
Tetrafunctional cyclobutanes tune toughness via network strand continuity	106
Programming stacking order in conducting van der Waals metal–organic frameworks through ligand aggregation	104
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	104
D3+ formation through photoionization of the molecular D2–D2 dimer	103
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	103
Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	101
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	100
Photomediated aliphatic C–H functionalization	99
Biocompatible ligand balancing in transition metal coordination enables benign in-cell protein arylation	98
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	98
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	98
Homogeneous multi-payload antibody–drug conjugates	98
A comprehensive model for the electric double layer of stepped platinum electrodes	97
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	97
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	97
Single-crystal to single-crystal editing of metal–organic frameworks via ligand removal	96

Constructing artificial gap junctions to mediate intercellular signal and mass transport	96
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	96
Superspreading and ultra-infiltrative coacervate mediates strong underwater adhesion on hydrated and lipidic substrates	96
Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	96
Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues	96
Challenges to developing materials for the transport and storage of hydrogen	95
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	95
Excitation energy transfer and vibronic coherence in intact phycobilisomes	95
Formal Diels–Alder reaction of saturated carboxylic acids via C–H activation	95
Pluralistic teaching	94
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	94
Emergence of specific binding and catalysis from a designed generalist binding protein	93
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	93
Generating extended foldamer dye stacks and unravelling their evolving exciton dynamics	92
An open-shell molecule that exhibits conformational dynamics	91
Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	90
Two roads to lithium nucleation	90
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	90
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	88
Discovering nickel enzymes within the aldo-keto reductase superfamily	87
Milking riboflavin for all it’s worth	86
Inverted metal-free active template synthesis of rotaxanes via axle‑mediated macrocyclization	85
Covalent organic frameworks as infinite building units for metal–organic frameworks with compartmentalized pores	85
4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	85
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	84
Three-dimensional van der Waals open frameworks	84
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	84
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	84
Transient water wires mediate selective proton transport in designed channel proteins	83
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	83
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	82
Leveraging electron donor–acceptor complexes for kinetic resolution in catalytic asymmetric photochemical synthesis	82
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	82
Photoswitchable coordination cages	81
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	81
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	80
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	79
In vivo metallophilic self-assembly of a light-activated anticancer drug	78
Working towards a new job	78
Engineered RNA sensors for tuberculosis detection	78
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	77
Something new under the sun	77
Construction of synthetic protein-binding non-genetic DNA systems in living cells	77
CO2 sorption in fluorinated non-porous coordination polymers	77
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	77
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	76
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	75
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	75
Supramolecular assembly of molecular wires alternating crown ethers and metal–halide complexes	75
Unravelling gas evolution mechanisms in battery electrode materials	74
An isolable germylyne radical with a one-coordinate germanium atom	74
Lattice O–O ligands in Fe-incorporated hydroxides enhance water oxidation electrocatalysis	74
The impact of UV light on synthetic photochemistry and photocatalysis	73
Iridium(III)-catalysed ionic hydrogenation of pyridines to multisubstituted piperidines	73
Anticancer platinum-based photo-oxidants in a new light	72
Thickness control of organic semiconductor-incorporated perovskites	72
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	71
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	71
Isolated and H2-reduced Anderson clusters catalyse low-temperature hydrogenation of CO2 to methanol	71
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	70
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	70
Non-statistical assembly of multicomponent [Pd2ABCD] cages	70
Strong dipole-promoted N–O bond hydrogenolysis enables ampere-level electrosynthesis of methylamine	70
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	70
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	69
A modifying touch for metal–organic framework glasses	69
Future-proofing calcium fluoride	67
Photoswitchable latent monomers enable on‑demand metathesis	67
Looking into luciferin	67
A third strand for protein–DNA interactions	67
Amino amide assembly	67
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	67
Cooperative ligands enable cobalt-catalysed hydrogenation	66
Checking out metal cluster chemistry from living libraries	66
Upcycling chlorinated trash into synthetic organic treasure	66
Sensing RNA	66
A crystalline stannyne	66
Janus-type emission from a cyclometalated iron(iii) complex	65
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	64
Triplet metallocarbenes featuring carbon-centred spin localization	64

How polymers dance to the pulses of ultrasound	64
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	64
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	64
Multi-compartment liposomes forge new paths in drug delivery	63
Driving movement in the field of molecular machines	63
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	62
Single-crystalline two-dimensional vinylene frameworks through topological conversion	62
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	61
Organocatalytic enantioselective synthesis of S(IV)-stereogenic sulfinamides enabled by an air-stable chiral phosphine	61
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	61
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	60
Quantum simulation of conical intersections using trapped ions	60
Isolation of halogen-substituted silylium ions	60
Masked alkynes for synthesis of threaded carbon chains	60
Asymmetric construction of sulfur(VI)–fluorine cores	59
Cyclopropenium functionalization	59
The importance of community as a pre-tenure faculty member	59
Establishing the fundamental rules for genetic code expansion	59
Mimicking the structure and function of tau folds associated with disease	59
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	58
A stable, crystalline nitrogen chain radical	58
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	58
Ribose at the heart of life	58
ChatGPT saves the day	58
Enantioconvergent radical addition of racemic alkyl halides to access vicinal stereocentres	57
A bismuth-based analogue of the π-allyl cation	57
Olefin π-coordination chemistry at low-oxidation-state boron	56
Non-enzymatic methylcyclization of alkenes	56
A lithium–aluminium heterobimetallic dimetallocene	56
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	56
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	56
Ligand-modulated metal–radical polarity match enables general 1,2-dicarbofunctionalization of ethylene	56
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	56
Programmable fluorescent aptamer-based RNA switches for rapid identification of point mutations	55
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	55
Polymer connectivity governs electrophotocatalytic activity in the solid state	55
Hyperpyramidalized alkenes with bond orders near 1.5 as synthetic building blocks	55
Copper-catalysed asymmetric cross-coupling reactions tolerant of highly reactive radicals	55
Encoding signal propagation on topology-programmed DNA origami	54
Hydration entropy of cations regulates chloride ion diffusion during electrochemical chlorine evolution	54
Chemical recycling of hydrofluorocarbons by transfer fluorination	54
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	54
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	53
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	53
Exciton annihilation in molecular aggregates suppressed through quantum interference	53
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	53
Author Correction: [2+2] Photocycloaddition reactions of sulfinylamines with alkenes to access β-sultam derivatives	53
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	52
Spontaneous trisulfide metathesis in polar aprotic solvents	52
Rings of power	51
Flexible interaction patches lead to building blocks with fluctuating valency	51
How many roads must a woman walk down?	51
A molecular sandwich with a lithium–aluminium filling	51
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	51
Author Correction: Moiré two-dimensional covalent organic framework superlattices	50
Reducing the carbon footprint of chemistry labs	50
Stereoselective alkylation of saturated heterocycles	50
Stannole dianions for axially coordinated lanthanide single-molecule magnets	49
Interweaving different metal–organic frameworks	49
Author Correction: Introducing metal–sulfur active sites in metal–organic frameworks via post-synthetic modification for hydrogenation catalysis	49
Hydrogenative double-bond deuteration	49
tRNA-deacylase-directed discovery of biosynthetic pathways	49
Colouring by force	49
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	48
Heteromultivalency enables enhanced detection of nucleic acid mutations	48
Doing away with radium’s proxies	48
Stepwise-controllable catalytic asymmetric Atherton–Todd reaction to access diverse P(V)-stereogenic compounds	48
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	48
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	47
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	47
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	46
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	46
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	46
Isolation and characterization of a two-coordinate phosphinidene oxide	46
Building ultramicroporous zirconium metal‒organic frameworks with ligands of high coordination density through a reticular approach	46
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	46
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	46
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	45
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	45
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	45
Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-based proteolysis-targeting chimeras	45
A para- to meta-isomerization of phenols	45
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	45
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	44
Copper catalysed asymmetric amination	44
From geranium lakes to catalysis with light	44
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	44
Publisher Correction: OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues	43
An unnatural base pair for the detection of epigenetic cytosine modifications in DNA	43
Critical race theory and its relevance for chemistry	43
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	43
Iterative synthesis of 1,3-polyboronic esters with high stereocontrol and application to the synthesis of bahamaolide A	43
Biosynthesis of an elusive sulfur-containing functional group	43
Vessel material determines product of enantioselective vinylcyclopropane rearrangement	43
Direct visualization of ligands on gold nanoparticles in a liquid environment	43