Nature Chemistry

Article	Citations
Not all catenanes with oriented rings are topologically chiral	438
General strategy for the synthesis of N-monofluoromethyl amides	303
Supramolecular crystals for hydrogen storage	292
DNA catch bonds demonstrate the art of getting stuck	256
Using symmetry to drive new protein assemblies	231
Pop-up rings to rule reactivity	226
Corrole and squeezed coordination	206
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	204
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	200
Controlling chromophore assembly and coupling via carbon nanohoops enables singlet fission at interchromophore distances up to 16 Å	175
Radical water opens parallel pathways in CO2 electrocatalysis	174
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	173
The numerous paths of ferrocene	172
Baird’s rules at the tipping point	171
Leveraging relaxation-optimized 1H–13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins	164
A near-linear lanthanide complex that displays magnet-like behaviour	163
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	163
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	159
Protons undermine lithium-ion batteries with positively disastrous results	158
Understanding single-molecule reactions using nanopore-based techniques	156
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	153
Reversible self-assembly of small molecules for recyclable solid-state battery electrolytes	152
Tunable valence tautomerism in lanthanide–organic alloys	150
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	147
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	147

Metal-hydroxyls mediate intramolecular proton transfer in heterogeneous O–O bond formation	147
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	146
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	143
Zigzag graphene nanoribbons with periodic porphyrin edge extensions	143
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	141
Charging imide anions for batteries	140
Single crystals of purely organic free-standing two-dimensional woven polymer networks	140
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	139
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	133
Enantiospecific cross-coupling of cyclic alkyl sulfones	132
Sulfone cross-coupling outcompetes proton transfer	132
Function without form in synthetic polymers mimicking protein hydration	132
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	132
A metalloenzyme platform for catalytic asymmetric radical dearomatization	131
Eric the AI research assistant for chemists	131
O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95	130
Global profiling of arginine reactivity and ligandability in the human proteome	128
Bridged bicycloalkanes through thermal [2+2] cycloaddition	128
Digital skills in chemical education	127
A soil-inspired dynamically responsive chemical system for microbial modulation	126
Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells	125
Chiral catalysis-driven rotary molecular motors	125
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	123
Beyond Hubble	123
D3+ formation through photoionization of the molecular D2–D2 dimer	120
Optical sequencing of single synthetic polymers	118
Excitation energy transfer and vibronic coherence in intact phycobilisomes	117
Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes	116
An electroaffinity labelling platform for chemoproteomic-based target identification	115
New-to-nature biocompatible chemistry for plastic waste upcycling	114
A template for artificial life	114
Constructing artificial gap junctions to mediate intercellular signal and mass transport	112
Aryl ortho methoxylation	112
ATP hydrolysis captured in atomic detail	112
A programmable biomimetic cytoskeleton	111
Heterogeneous polymer designs that bring electricity, light and substrates together	110
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	109
Photomediated aliphatic C–H functionalization	109
Bridging aqueous electrochemistry and non-aqueous chemistry for chemical production	109
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	108
Bottleable triplet nitrenes	106
Biocompatible ligand balancing in transition metal coordination enables benign in-cell protein arylation	106
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	103
Homogeneous multi-payload antibody–drug conjugates	102
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	102
A comprehensive model for the electric double layer of stepped platinum electrodes	102
Superspreading and ultra-infiltrative coacervate mediates strong underwater adhesion on hydrated and lipidic substrates	101
Single-crystal to single-crystal editing of metal–organic frameworks via ligand removal	101
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	100
Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues	99

Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	99
Tetrafunctional cyclobutanes tune toughness via network strand continuity	95
Protecting skins of Au–Cl can stabilize Au nanostructures	95
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	94
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	94
A dynamic metal–organic framework photocatalyst	94
Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	92
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	92
Challenges to developing materials for the transport and storage of hydrogen	92
Formal Diels–Alder reaction of saturated carboxylic acids via C–H activation	92
Aromaticity rules	92
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	91
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	90
Milking riboflavin for all it’s worth	90
Pluralistic teaching	90
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	89
An open-shell molecule that exhibits conformational dynamics	89
Two roads to lithium nucleation	88
Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	87
In vivo metallophilic self-assembly of a light-activated anticancer drug	87
Transient water wires mediate selective proton transport in designed channel proteins	86
Three-dimensional van der Waals open frameworks	86
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	86
Generating extended foldamer dye stacks and unravelling their evolving exciton dynamics	86
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	85
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	85
Leveraging electron donor–acceptor complexes for kinetic resolution in catalytic asymmetric photochemical synthesis	85
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	85
4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	84
Covalent organic frameworks as infinite building units for metal–organic frameworks with compartmentalized pores	84
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	83
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	83
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	83
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	82
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry	82
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	81
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	81
Photoswitchable coordination cages	81
Working towards a new job	80
Isolated and H2-reduced Anderson clusters catalyse low-temperature hydrogenation of CO2 to methanol	79
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	79
Engineered RNA sensors for tuberculosis detection	79
Iridium(III)-catalysed ionic hydrogenation of pyridines to multisubstituted piperidines	79
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	78
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	78
Strong dipole-promoted N–O bond hydrogenolysis enables ampere-level electrosynthesis of methylamine	77
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	77
The impact of UV light on synthetic photochemistry and photocatalysis	77
An isolable germylyne radical with a one-coordinate germanium atom	77
Anticancer platinum-based photo-oxidants in a new light	77
Construction of synthetic protein-binding non-genetic DNA systems in living cells	76
CO2 sorption in fluorinated non-porous coordination polymers	76
Supramolecular assembly of molecular wires alternating crown ethers and metal–halide complexes	76
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	75
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	75
Lattice O–O ligands in Fe-incorporated hydroxides enhance water oxidation electrocatalysis	75
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	73
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	73
Something new under the sun	73
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	71
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	70
Unravelling gas evolution mechanisms in battery electrode materials	70
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	69
A third strand for protein–DNA interactions	69
Non-statistical assembly of multicomponent [Pd2ABCD] cages	69
Triplet metallocarbenes featuring carbon-centred spin localization	69
Thickness control of organic semiconductor-incorporated perovskites	69
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	69
Upcycling chlorinated trash into synthetic organic treasure	68
Photoswitchable latent monomers enable on‑demand metathesis	68
Looking into luciferin	67
Single-crystalline two-dimensional vinylene frameworks through topological conversion	67
Chiral control of spin-crossover dynamics in Fe(II) complexes	67
Future-proofing calcium fluoride	67
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	67
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	67
Amino amide assembly	66
Sensing RNA	66
Heart of glass	66
Checking out metal cluster chemistry from living libraries	66

Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	65
Cooperative ligands enable cobalt-catalysed hydrogenation	64
Organocatalytic enantioselective synthesis of S(IV)-stereogenic sulfinamides enabled by an air-stable chiral phosphine	63
How polymers dance to the pulses of ultrasound	63
Isolation of halogen-substituted silylium ions	63
Quantum simulation of conical intersections using trapped ions	63
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	62
A crystalline stannyne	62
Masked alkynes for synthesis of threaded carbon chains	62
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	62
Multi-compartment liposomes forge new paths in drug delivery	62
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	61
Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways	61
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	60
Janus-type emission from a cyclometalated iron(iii) complex	60
Asymmetric construction of sulfur(VI)–fluorine cores	60
The importance of community as a pre-tenure faculty member	60
Establishing the fundamental rules for genetic code expansion	60
Ribose at the heart of life	59
Electric field maps in enzymes	59
Cyclopropenium functionalization	59
Chemical recycling of hydrofluorocarbons by transfer fluorination	59
Structure-specific amyloid precipitation in biofluids	59
Mimicking the structure and function of tau folds associated with disease	59
A bismuth-based analogue of the π-allyl cation	59
Programmable fluorescent aptamer-based RNA switches for rapid identification of point mutations	59
Enantioconvergent radical addition of racemic alkyl halides to access vicinal stereocentres	58
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	58
Olefin π-coordination chemistry at low-oxidation-state boron	58
ChatGPT saves the day	57
A stable, crystalline nitrogen chain radical	57
Polymer connectivity governs electrophotocatalytic activity in the solid state	56
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	56
Non-enzymatic methylcyclization of alkenes	56
Encoding signal propagation on topology-programmed DNA origami	56
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	56
Exciton annihilation in molecular aggregates suppressed through quantum interference	56
Hydration entropy of cations regulates chloride ion diffusion during electrochemical chlorine evolution	56
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	55
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	55
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	55
On gene silencing by the X10-23 DNAzyme	55
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	55
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	55
A lithium–aluminium heterobimetallic dimetallocene	54
Hyperpyramidalized alkenes with bond orders near 1.5 as synthetic building blocks	54
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	54
Copper-catalysed asymmetric cross-coupling reactions tolerant of highly reactive radicals	53
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	53
Spontaneous trisulfide metathesis in polar aprotic solvents	53
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	52
How many roads must a woman walk down?	52
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	52
Rings of power	52
A molecular sandwich with a lithium–aluminium filling	51
Reducing the carbon footprint of chemistry labs	51
Stepwise-controllable catalytic asymmetric Atherton–Todd reaction to access diverse P(V)-stereogenic compounds	51
Flexible interaction patches lead to building blocks with fluctuating valency	51
Hydrogenative double-bond deuteration	51
Colouring by force	51
Stereoselective alkylation of saturated heterocycles	51
Interweaving different metal–organic frameworks	51
Isolation and characterization of a two-coordinate phosphinidene oxide	50
Author Correction: Moiré two-dimensional covalent organic framework superlattices	50
Heteromultivalency enables enhanced detection of nucleic acid mutations	50
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	50
Author Correction: Introducing metal–sulfur active sites in metal–organic frameworks via post-synthetic modification for hydrogenation catalysis	50
Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-based proteolysis-targeting chimeras	49
Doing away with radium’s proxies	49
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	49
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	49
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	49
tRNA-deacylase-directed discovery of biosynthetic pathways	48
A para- to meta-isomerization of phenols	48
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	47
Stannole dianions for axially coordinated lanthanide single-molecule magnets	47
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	47
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	46
Building ultramicroporous zirconium metal‒organic frameworks with ligands of high coordination density through a reticular approach	46
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	46
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	46
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	45
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	45
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	45
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	45
Enhanced active-site electric field accelerates enzyme catalysis	45
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	45
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	45
Carbonyl cross-metathesis via deoxygenative gem-di-metal catalysis	45
Time-resolved terahertz–Raman spectroscopy reveals that cations and anions distinctly modify intermolecular interactions of water	44
Emulsion-oriented assembly for Janus double-spherical mesoporous nanoparticles as biological logic gates	44
Selective arylation of atypical C–F bonds in polyfluoroarenes with aryl chlorides	44
Navigating protein landscapes with a machine-learned transferable coarse-grained model	44
Critical race theory and its relevance for chemistry	44
Progress and pitfalls in designing heterogeneous catalysts with molecular precision	43