OOIR: Observatory of International Research

Papers

(The H4-Index of Disease Models & Mechanisms is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
miRNA interplay: mechanisms and consequences in cancer	336
Mitochondrial function in development and disease	81
The RASopathies: from pathogenetics to therapeutics	61
Mouse models of myocardial infarction: comparing permanent ligation and ischaemia-reperfusion	54
Hyperuricemia causes kidney damage by promoting autophagy and NLRP3-mediated inflammation in rats with urate oxidase deficiency	50
Pulmonary neuroendocrine cells: physiology, tissue homeostasis and disease	48
Hyperoxia-induced bronchopulmonary dysplasia: better models for better therapies	43
Modelling epilepsy in the mouse: challenges and solutions	40
Advancing lung organoids for COVID-19 research	39
Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors human APOL1 kidney disease	37
Defining RASopathy	37
Interpreting protein variant effects with computational predictors and deep mutational scanning	36
Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability	36
The power of Drosophila in modeling human disease mechanisms	34
The clinical manifestations, molecular mechanisms and treatment of craniosynostosis	33
Metabolomics and lipidomics in Caenorhabditis elegans using a single-sample preparation	33
Autosomal recessive osteopetrosis: mechanisms and treatments	32
Mycobacteriophage–antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus	31
Sex differences in insulin resistance, but not peripheral neuropathy, in a diet-induced prediabetes mouse model	30
Humanized yeast to model human biology, disease and evolution	29
Pyroptosis in host defence against bacterial infection	29
Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation	28
Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis	28
Caenorhabditis elegans for rare disease modeling and drug discovery: strategies and strengths	26
Intestinal barrier dysfunction: an evolutionarily conserved hallmark of aging	26

A scalable, clinically severe pig model for Duchenne muscular dystrophy