OOIR: Observatory of International Research

Papers

(The H4-Index of Disease Models & Mechanisms is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Let's talk about sex… obesity and melanoma	101
Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment	93
Drop the MYC: An expansion of triple-negative breast cancer driver genes	62
Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia	51
A chance to turn HIV treatment up a Notch	47
Molecular functions of ANKLE2 and its implications in human disease	45
Biological and therapeutic insights from animal modeling of fusion-driven pediatric soft tissue sarcomas	44
Optimized methods to image hepatic lipid droplets in zebrafish larvae	44
RNA sequencing reveals molecular mechanisms of endometriosis lesion development in mice	44
Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy	41
Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntington's Disease Mouse Models	41
The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice	40
Prostatic Escherichia coli infection drives CCR2-dependent recruitment of fibrocytes and collagen production	39
CIB2 function is distinct from that of whirlin in the organization of sterocilia architecture	39
Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury	33
Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila	33
Cancer cachexia: lessons from Drosophila	32
Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons	32
Metabolism navigates neural cell fate in development, aging and neurodegeneration	31
Human organoid model of pontocerebellar hypoplasia 2a recapitulates brain region-specific size differences	30
Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue	29
First person – Nichole Link	29
Advancing lung organoids for COVID-19 research	29
Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants	27
First person – Sheeza Mughal	27

Latent TGFβ-binding proteins 1 and 3 protect the larval zebrafish outflow tract from aneurysmal dilatation	27
First person – Mayra Fernanda Martínez-López	26
Validity of Xiphophorus fish as models for human disease	26