OOIR: Observatory of International Research

Papers

(The TQCC of Biomarkers in Medicine is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Evaluation of serum salusin-α and β levels in patients with obstructive sleep apnea	39
Relationship Between Blood Viscosity and No-Reflow Phenomenon in St-Segment Elevation Myocardial Infarction Performed in Primary Percutaneous Coronary Interventions	33
AAT: Does it have a Place in Acute Leukemia?	29
Immune nutrition indices are associated with disease activity in rheumatoid arthritis: a cross-sectional study	28
NLR as prognostic biomarker for metastatic renal cell carcinoma patients treated with cytoreductive nephrectomy	26
Predictive value of the Naples prognostic score for no-reflow phenomenon after saphenous vein graft stenting	22
Plasma Endostatin Correlates with Hypoxia and Mortality in Covid-19-Associated Acute Respiratory Failure	21
Neutrophil-to-Serum Iron Ratio as a Promising Inflammatory Biomarker for Acute Myocardial Infarction and Gensini Score	21
Relationship between HE4 levels and metabolic parameters in PET of non-small cell lung cancer patients	21
Impact of Naples Prognostic Score on Midterm All-Cause Mortality in Patients with Decompensated Heart Failure	20
Prognostic Value of Serum Albumin for Long-Term Mortality in Patients with Dual-Chamber Permanent Pacemakers	20
Elevated neutrophil-to-hemoglobin ratio as an indicator of poor survival in hepatitis B virus-related decompensated cirrhosis	19
Evaluation of primary markers of inflammation and the systemic inflammation index in specific learning disabilities	18
Prognostic Value of Stc1 in Solid Tumors: A Meta-Analysis	18
Reference Interval for Urinary Neutrophil Gelatinase-Associated Lipocalin in Healthy Adults in Jiangsu Region in Eastern China: A Multicenter Study	18
Torquetenovirus in bronchoalveolar lavage fluid for early detection of pulmonary infections in immunocompromised hosts	17
Biomarkers in Exhaled Breath Condensate as Fingerprints of Asthma, Chronic Obstructive Pulmonary Disease and Asthma–Chronic Obstructive Pulmonary Disease Overlap: A Critical Review	17
Predictive Value of A Novel Lncrna LINC02518 in Evaluating the Prognosis of Patients with Hepatocellular Carcinoma	15
Altered T-Cell Profile in Sickle Cell Disease	15
Wnt/β-Catenin Pathway Proteins in End-Stage Renal Disease	15
Meta-Analysis of Initial Natriuretic Peptides in the Setting of Sepsis-Induced Myocardial Dysfunction	14
A Comprehensive Review of Novel Biomarkers in the Diagnosis of Intrahepatic Cholestasis of Pregnancy	14
The association between HbA1c/C-peptide levels and short-term mortality in patients diagnosed with myocardial infarction	13
Examining Variation and Temporal Dynamics of Extracellular Matrix Biomarkers Following Acute Myocardial Infarction	13
Predictive Value of Serum Lncrna MALAT1 for the Recurrence of Persistent Atrial Fibrillation After Radiofrequency Ablation	13

Novel Biomarkers for Acute Respiratory Distress Syndrome: Genetics, Epigenetics and Transcriptomics	12
The Potential of Mir-499 Plasmatic Level As A Biomarker Of Obstructive Sleep Apnea Syndrome	12
Application of 24-H Respiratory Rate and Oxygenation Index Variation to Predict the Outcome of High-Flow Nasal Cannula Therapy in Patients with Acute Hypoxemic Respiratory Failure in a Respiratory Int	11
Lymphocyte-To-Monocyte Ratio Predicts Survival After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy	11
Low Serum Pepsinogen II Levels are Closely Linked with a Risk of Metabolic Syndrome among Healthy Individuals with Asymptomatic HELICOBACTER PYLORI Infection: A Cross-Se	11
IL6R Gene Polymorphisms and Their Relation to Chronic Obstructive Pulmonary Disease Susceptibility in the Chinese Population	11
Novel Marker for Predicting the Severity and Prognosis of Acute Pulmonary Embolism: Platelet-To-Hemoglobin Ratio	11
Prognostic Impact of Cardiohepatic Syndrome in Patients with St-Segment Elevation Myocardial Infarction	11
Comprehensive biomarker profiles in hematological malignancies: improving diagnosis, prognosis, and treatment	10
Itga7 Relates to Disease Risk, Pathological Feature, Treatment Response and Survival in Ph ^– Acute Lymphoblastic Leukemia	10
Designing A Fluorescence Padlock Probe-Based Biosensor and Colorimetric Assay For The Detection of G12D KRAS Mutation	10
Vitamin D Level Predicts Angiographic No-Reflow Phenomenon After Percutaneous Coronary Intervention in Patients with St Segment Elevation Myocardial Infarction	10
Can Anticarbamylated Protein Antibodies Be Used to Support the Diagnosis of Systemic Lupus Erythematosus?	10
Integrative Analysis of the Proteome and Transcriptome in Gastric Cancer Identified Lrp1B As A Potential Biomarker	10
Prognostic Value of Lymphocyte–C-Reactive Protein Ratio in Patients with Liver Cancer: A Meta-Analysis	10
Preoperative Monocyte to High-Density Lipoprotein Ratio as a Predictor of Survival Outcome of Gastric Cancer Patients After Radical Resection	9
TCF21 rs2327429 and TCF21 rs12190287 are Associated with Colorectal Cancer in a Chinese Population	9
Nt-Probnp/Urine Hepcidin-25 Ratio and Cardiorenal Syndrome Type 1 in Patients with Severe Symptomatic Aortic Stenosis	8
Association Between the Rs3733846 in the Flanking Region of Mir-143/145 and Risk of Cervical Squamous Cell Carcinoma	8
Modulation of Soluble Receptor for Advanced Glycation End Products Isoforms and Advanced Glycation End Products in Long-Living Individuals	8
Exploring novel perspectives on eosinophilic inflammation in severe asthma	8
Reliable Epithelial–Mesenchymal Transition Biomarkers for Colorectal Cancer Detection	8
Ferroptosis-Related Genes Are Candidate Diagnostic and Prognostic Biomarkers for Skin Cutaneous Melanoma	8
Endothelial Biomarkers of Thrombosis in Critically Ill Patients with Acquired Coagulopathy: A Prospective Cohort Study	8
Relation of A Novel Fibrosis Marker and Post-Myocardial Infarction Left Ventricular Ejection Fraction in Revascularized Patients	8
Serum Circulating Free Dna of Syncytin-1 As A Novel Molecular Marker for Early Diagnosis of Non-Small-Cell Lung Cancer	8
Fecal Calprotectin as an Intestinal Inflammation Marker is Elevated in Glaucoma	8
Diagnostic role of circulating cell-free DNA in schizophrenia and neuro-degenerative disorders	8
Prognostic and Clinicopathological Significance of Mmp12 in Various Cancers: A Meta-Analysis and Bioinformatics Analysis	8
Relationship Between Systemic Immune-Inflammation Index and No-Reflow in Percutaneous Coronary Intervention for Saphenous Grafts	8
Prognostic value of C-reactive protein in patients with glioma: a meta-analysis	7
Feasibility Evaluation of Hsa_Circ_0005480 As An Auxiliary Diagnostic and Prognostic Indicator for Gastric Cancer	7
Investigating Adamts7 and Adamts12 Levels in Prediabetic and Type 2 Diabetic Patients	7
Predictive power of ALBI score-based nomogram for 30-day mortality following transcatheter aortic valve implantation	7
The relationship between serum Lumican levels and myocardial fibrosis in patients with hypertrophic cardiomyopathy	7
Prognostic Value of Triglyceride/Glucose Index in Patients with St-Segment Elevation Myocardial Infarction	7
Association Of Vitamin B12/Ferritin Deficiency In Cancer Patients with Methylomic Changes At Promotors of TET Methylcytosine Dioxygenases	7
Serum vitamin D, hemoglobin A1c and vitamin B12 levels in patients with gingivitis and periodontitis stages	7
Comparison of the effect of Uric Acid/Albumin Ratio on Coronary Slow Flow with Other Inflammation-Based Markers	7
Low Vitamin K Status, High Sclerostin and Mortality Risk of Stable Coronary Heart Disease Patients	7
Nomogram for Predicting Prolonged Postoperative Ileus in Colorectal Cancer Based on Age and Inflammatory Markers	7
Serum CDC42 Reflects the Exacerbation Risk and Severity, Th1/2 Cell Imbalance and Inflammation in Asthmatic Children	7
Role of Triglyceride Glucose Index in Long-Term Mortality of Patients with Lower Extremity Arterial Disease	7
Evaluation of Hsp70 Levels in Ectopic Pregnancy, Abortus Imminens and Intrauterine Pregnancy	7
Copy Number Alteration Signatures As Biomarkers in Cancer: A Review	7
PLK3 is linked with higher tumor stage and unfavorable prognosis in patients with colorectal cancer	7
Gender Differences Contribute to Variability of Serum Lipid Biomarkers for Alzheimer'S Disease	7
Relationship Between Disease Severity and Myeloperoxidase in Chronic Viral Hepatitis: A Prospective Study	6
Correlation Between BTG3 , Casp9 and Lrp4 Single-Nucleotide Polymorphisms and Susceptibility to Papillary T	6
Blood MALT1 reflects acute exacerbation risk and inflammation in elderly chronic obstructive pulmonary disease patients	6

Novel Biomarker-Based Score (Sad-60) for Predicting Mortality in Patients with Covid-19 Pneumonia: A Multicenter Retrospective Cohort of 1013 Patients	6
Urinary Iodine Concentration and Radioactive Iodine Therapeutic Response in Patients with Differentiated Thyroid Cancer	6
Interaction between coagulation and inflammatory system in liver disease: re-focus on hematological markers	6
Can C-Reactive Protein be Used As a Surrogate Marker of IL-6 in a Broad Array Of Clinical Entities?	6
3′ Untranslated Region Variants in DEFA5 Gene Associated with Susceptibility to Iga Nephropathy in the Chinese Han Population	6
Upregulation of the Transmembrane Protease Serine 3 Mrna Level in Radioresistant Colorectal Cancer Tissues	6
KELIM score predicts outcome in patients with platinum-resistant/refractory recurrent ovarian cancer	6
Methemoglobin in critically ill septic patients	6
The difference in core–surface temperature indicates the prognosis of heart failure patients	5
Long-Term Stability and Age-Dependence of Six Regulatory Serum Proteins	5
Association Between Serum Homocysteine and Postoperative Acute Kidney Injury in Patients Undergoing Cardiac Surgery	5
Immune biomarkers for predicting postoperative pneumonia following hip fracture surgery	5
Risk Prediction Model of In-Hospital Mortality in Heart Failure with Preserved Ejection Fraction and Mid-Range Ejection Fraction: A Retrospective Cohort Study	5
Evaluation of the Relationship Between Aspartate Aminotransferase/Alanine Aminotransferase Ratio and Coronary Slow-Flow Phenomenon	5
Meningitis Patients with Pneumonia: Correlation Between Blood Parameters and Clinical Features	5
Utility of Inflammatory Biomarkers in Patients with Covid-19 Infections: Bahrain Experience	5
Evaluation of A Multimarker Panel in Chronic Heart Failure: A 10-Year Follow-Up	5
Association Between Endothelial Biomarkers and Lipid and Glycemic Levels: A Cross-Sectional Study with Diabetic Patients	5
Mirnas As Biomarkers of Adverse Drug Reactions to Platinum-Based Agents in Patients with Non-Small-Cell Lung Cancer	5
Prognostic Significance of Serum Lactate Following Cardiac Transplantation	5
Analyzing venous thromboembolism risk in malignant tumors: thromboelastogram and coagulation factors study	5
Prognostic Nutritional Index and Crp, Age, Platelet Count, Albumin Level Score in Predicting Mortality and Intensive Care Unit Admission for Covid-19	5
Changes in Lactate Dehydrogenase on Admission Throughout the Covid-19 Pandemic and Possible Impacts on Prognostic Capability	5
Association between inflammatory markers and anemia in patients with diabetic foot ulcer	5
High-Density Lipoprotein-Related Inflammatory Indices Predict Repeat Revascularization in Coronary Drug-Eluting Stenting	5
Preoperative Red Cell Distribution Width to Lymphocyte Ratio As Biomarkers for Prolonged Intensive Care Unit Stay Among Older Patients Undergoing Cardiac Surgery: A Retrospective Longitudinal Study	5
Lncrna Neat1 Correlates with TH1 and TH17 and Could Serve as an Assistant Biomarker in Sepsis	4
Blood Biomarkers: A New Solution to the Silent Pandemic of Traumatic Brain Injury	4
A Novel Cuproptosis-Related lncRNA Prognostic Signature in Thyroid Cancer	4
Killing Three Birds with One Stone: Lncrna Malat1 As A Multifunctional Biomarker in Atherosclerotic Cardiovascular Disease	4
KELIM score predicts outcome in patients with platinum-resistant/refractory recurrent ovarian cancer	4
Aurora-B: a novel biomarker in the invasion and metastasis of osteosarcoma	4
Value of Galectin-3 in the Diagnosis of Acute Coronary Syndrome and the Assessment of Coronary Artery Lesions	4
Factors Associated with Baseline and Serial Changes in Circulating Nt-Probnp and High-Sensitivity Cardiac Troponin T in A Population-Based Cohort (Dallas Heart Study)	4
Value of Brain Damage Biomarkers in Cerebrospinal Fluid in Neonates with Hypoxic–Ischemic Brain Injury	4
Elevated serum vitamin B12 concentrations in a patient with pancreatic exocrine insufficiency	4
Nomogram Based on Neutrophil-To-Platelet Ratio to Predict In-Hospital Mortality in Infective Endocarditis	4
Predicting cerebral infarction in tuberculous meningitis and its prognostic significance	4
Implications of Raftlin in different diseases: from molecular biology to diagnostic value	4
Decreased Circulating Dipeptidyl Peptidase-4 Enzyme Activity Is Prognostic for Severe Outcomes in Covid-19 Inpatients	4
Predicting Long-Term Cardiovascular Outcomes in Myocardial Infarction Survivors Using Multiple Biomarkers	4
Detection of Infections by Computerized Capture of Peaks in Longitudinally Measured C-reactive Protein Levels	4
PRAMEF12 , a novel cancer/testis gene, regulates proliferation and apoptosis to promote progression of glioma	4
Novel Kidney Injury Biomarkers in A Large Cohort of Children with Sickle Cell Anemia	4
Update prognostic potency of surfactant protein D (SP-D) in the COVID-19 landscape: an In-depth meta-analytical exploration	4
A novel indicator of all-cause mortality in acute coronary syndrome: the CALLY index	4
Prognostic role of systemic immune-inflammation index versus other cardiac markers in acute myocarditis in young adults	4
Urinary Tubular Biomarkers As Predictors of Death in Critically Ill Patients with Covid-19	4
Could Serum HMGB1 Levels be a Predictor Associated with Psoriatic Arthritis?	4
Assessing the Clinical Utility of Major Indices for Nonalcoholic Fatty Liver Disease in East Asian Populations	4
Osteopontin and Galectin-3 As Biomarkers of Maladaptive Right Ventricular Remodeling In Pulmonary Hypertension	4