OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Pharmacology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence	165
Blinding and expectancy confounds in psychedelic randomized controlled trials	146
Pharmacological Management of Postmenopausal Osteoporosis: a Level I Evidence Based - Expert Opinion	65
Rapid review of suspected adverse drug events due to remdesivir in the WHO database; findings and implications	46
Pathophysiology, diagnosis, and pharmacological treatment of prurigo nodularis	45
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	42
Molecular docking and dynamics study to explore phytochemical ligand molecules against the main protease of SARS-CoV-2 from extensive phytochemical datasets	37
Clinical pharmacology and PK/PD translation of the second-generation Bruton’s tyrosine kinase inhibitor, zanubrutinib	36
An update on the complex relationship between clozapine and pneumonia	34
Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress	34
Update on the effects of GLP-1 receptor agonists for the treatment of polycystic ovary syndrome	34
Pharmacokinetic/pharmacodynamic target attainment in critically ill renal patients on antimicrobial usage: focus on novel beta-lactams and beta lactams/beta-lactamase inhibitors	34
Genetic testing in patients undergoing percutaneous coronary intervention: rationale, evidence and practical recommendations	33
Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis	30
Review of galectin-3 inhibitors in the treatment of nonalcoholic steatohepatitis	29
Prediction of vancomycin dose on high-dimensional data using machine learning techniques	29
Omega-3 polyunsaturated fatty acids focusing on eicosapentaenoic acid and docosahexaenoic acid in the prevention of cardiovascular diseases: a review of the state-of-the-art	27
The Role of testosterone treatment in patients with metabolic disorders	26
Afamelanotide for prevention of phototoxicity in erythropoietic protoporphyria	26
Novel therapies for AML: a round-up for clinicians	24
Prevention of colistin induced nephrotoxicity: a review of preclinical and clinical data	24
UK Medical Cannabis registry: an analysis of clinical outcomes of medicinal cannabis therapy for chronic pain conditions	23
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	23
An update on drug development for the treatment of nonalcoholic fatty liver disease – from ongoing clinical trials to future therapy	23
Update on diagnosis and treatment of immune thrombocytopenia	22

UK Medical Cannabis Registry: an analysis of clinical outcomes of medicinal cannabis therapy for generalized anxiety disorder	22
Pharmacological control of pain during propofol injection: a systematic review and meta-analysis	22
Safety and efficacy of therapies for chylomicronemia	22
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	22
Who is blind in psychedelic research? Letter to the editor regarding: blinding and expectancy confounds in psychedelic randomized controlled trials	21
Prevalence of polymorphisms in thiopurine metabolism and association with adverse outcomes: a South Asian region-specific systematic review and meta-analysis	21
Clinical pharmacology of antiplatelet drugs	20
Hippocampal volume, function, and related molecular activity in anorexia nervosa: A scoping review	20
The protective effect of tanshinone IIa on endothelial cells: a generalist among clinical therapeutics	19
Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women	19
Vaccination and their importance for lung transplant recipients in a COVID-19 world	18
SARS-CoV-2 protein drug targets landscape: a potential pharmacological insight view for the new drug development	18
Induction and maintenance of procedural sedation in adults: focus on remimazolam injection	18
Current status and prospects of IL-6–targeting therapy	18
Opioid epidemic: lessons learned and updated recommendations for misuse involving prescription versus non-prescription opioids	17
The role of PCSK9 in NAFLD/NASH and therapeutic implications of PCSK9 inhibition	17
Novel pharmacological therapies for the treatment of endometriosis	17
Detection of mobile colistin-resistance gene variants (mcr-1andmcr-2) in urinary tract pathogens in Bangladesh: the last resort of infectious disease management colistin efficacy is unde	16
Sex differences in COPD management	16
Drug delivery and targeting to brain tumors: considerations for crossing the blood-brain barrier	16
Finerenone: a mineralocorticoid receptor antagonist for the treatment of chronic kidney disease associated with type 2 diabetes	16
The value of deprescribing in older adults with dementia: a narrative review	16
Recent advances and future perspectives in the pharmacological treatment ofCandida aurisinfections	16
Selective FGFR/FGF pathway inhibitors: inhibition strategies, clinical activities, resistance mutations, and future directions	15
Recent advances in clearance monitoring of monoclonal antibodies in patients with inflammatory bowel diseases	15
Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials	15
Opioids for chronic low back pain management: a Bayesian network meta-analysis	15
Population pharmacokinetics of oxcarbazepine: a systematic review	14
Clinical trials with plants in diabetes mellitus therapy: a systematic review	14
WHO collaborative registration procedure using stringent regulatory authorities’ medicine evaluation: reliance in action?	14
Cannabidiol drug interaction considerations for prescribers and pharmacists	14
The association between the use of sodium glucose cotransporter 2 inhibitor and the risk of diabetic retinopathy and other eye disorders: a systematic review and meta-analysis	14
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	14
Adverse events associated with nilotinib in chronic myeloid leukemia: mechanisms and management strategies	13
Efficacy and safety of injectable deoxycholic acid for submental fat reduction: a systematic review and meta-analysis of randomized controlled trials	13
The impact of body composition on treatment in ovarian cancer: a current insight	13
Peyronie’s disease: pharmacological treatments and limitations	13
Givosiran for the treatment of acute hepatic porphyria	13
Dostarlimab for the treatment of advanced endometrial cancer	13
Methotrexate and cardiovascular risk in rheumatic diseases:A comprehensive review	13
How do nocebo effects in placebo groups of randomized controlled trials provide a possible explicative framework for the COVID-19 pandemic?	13
Targeting the spectrum of immune checkpoints in prostate cancer	13
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life	13
Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	12
Prescription patterns of antiseizure drugs in tuberous sclerosis complex (TSC)-associated epilepsy: a multicenter cohort study from Germany and review of the literature	12
Treatment of infections in cancer patients: an update from the neutropenia, infection and myelosuppression study group of the Multinational Association for Supportive Care in Cancer (MASCC)	12
Cannabinoids and drug metabolizing enzymes: potential for drug-drug interactions and implications for drug safety and efficacy	12
Aminoadamantanes: from treatment of Parkinson’s and Alzheimer’s disease to symptom amelioration of long COVID-19 syndrome?	11
How to handle the delayed or missed dose of rivaroxaban in patients with non-valvular atrial fibrillation: model-informed remedial dosing	11
Clinical pharmacology of siRNA therapeutics: current status and future prospects	11

Quantitative efficacy of L-carnitine supplementation on glycemic control in type 2 diabetes mellitus patients	11
Perspectives on the pharmacological management of psoriasis in pediatric and adolescent patients	11
Patient initiation and maintenance of GLP-1 RAs for treatment of obesity	11
The effect of different contraceptive methods on the vaginal microbiome	11
The new European guidelines for prevention of cardiovascular disease are misleading	10
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	10
Effects of metformin on body weight in polycystic ovary syndrome patients: model-based meta-analysis	10
Oral acetazolamide for intraocular pressure lowering: balancing efficacy and safety in ophthalmic practice	10
Efficacy and safety of liraglutide for obesity and people who are overweight: a systematic review and meta-analysis of randomized controlled trials	10
Treatment challenges in adult female acne and future directions	10
Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities	10
Assessing the potential for drug interactions and long term safety of melatonin for the treatment of insomnia in children with autism spectrum disorder	10
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	10
Metformin adverse event profile: a pharmacovigilance study based on the FDA Adverse Event Reporting System (FAERS) from 2004 to 2022	10
The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack	10
Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations	10
BNT162b2 mRNA COVID-19 vaccine is safe in a setting of patients on biologic therapy with inflammatory bowel diseases: a monocentric real-life study	10
Compounds of plants with activity against SARS-CoV-2 targets	10
Growing role of SGLT2i in heart failure: evidence from clinical trials	9
Impact of red yeast rice supplementation on lipid profile: a systematic review and meta-analysis of randomized-controlled trials	9
Radical metastasectomy followed by sorafenib versus observation in patients withclear cell renal cell carcinoma: extended follow -up of efficacy results from the randomized phase II RESORT trial	9
Classes of drugs that target the cellular components of inflammation under clinical development for COPD	9
The effect of inhaled corticosteroids on the outcomes of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials	9
Pharmaceuticals agents for preventing NSAID-induced gastric ulcers: a patent review	9
Hematological toxicities associated with linezolid therapy in adults: key findings and clinical considerations	9
Clinical pharmacological innovation in the treatment of depression	9
Profiles of polypharmacy in older adults and medication associations with signs of aspiration	9
Characteristics and clinical influence factors of arsenic species in plasma and their role of arsenic species as predictors for clinical efficacy in acute promyelocytic leukemia (APL) patients treated	8
Reliance: a smarter way of regulating medical products - The IPRP survey	8
Cenobamate tablets as a treatment for focal-onset seizures in adults	8
Effect of Perioperative Ketamine on Postoperative Mood and Depression: A Review of the Literature	8
Emapalumab for adult and pediatric patients with hemophagocytic lymphohistiocytosis	8
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	8
Sex and gender differences in the treatment of arterial hypertension	8
Pharmacological management of fibromyalgia: a Bayesian network meta-analysis	8
Lenvatinib: established and promising drug for the treatment of advanced hepatocellular carcinoma	8
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations	8
Reliance is key to effective access and oversight of medical products in case of public health emergencies	8
Treatment options following metformin in primary prevention populations with type 2 diabetes: which is the right road to take?	8
Clinical efficacy and safety of apatinib as maintenance treatment in patients with advanced esophageal squamous cell carcinoma	8
Nephroprotective effects of febuxostat and/or mirtazapine against gentamicin-induced nephrotoxicity through modulation of ERK 1/2, NF-κB and MCP1	8
Biologic and advanced immunomodulating therapeutic options for sarcoidosis: a clinical update	8
pre-existing diabetes and PTDM in kidney transplant recipients: how to handle immunosuppression	8
Real-world effectiveness of olanzapine and risperidone in the treatment of schizophrenia in Brazil over a 16-year follow-up period; findings and implications	8
Ibuprofen and postoperative bleeding in children undergoing tonsillectomy or adenotonsillectomy: a systematic review and meta-analysis of randomized clinical trials.	7
Novel and emerging treatment strategies for lupus nephritis	7
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	7
Potential clinical applications of Ashwagandha (Withania somnifera) in medicine and neuropsychiatry	7
Treatment options for children with multi-drug resistant tuberculosis	7
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	7
Epoprostenol for the treatment of pulmonary arterial hypertension	7
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	7
Keeping up with venetoclax for leukemic malignancies: key findings, optimal regimens, and clinical considerations	7
Cannabidiol in low back pain: scientific rationale for clinical trials in low back pain	7
Clinical pharmacology of SGLT-2 inhibitors in heart failure	7
Favipiravir-based treatment for outcomes of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials	7
Do patients with immune-mediated thrombotic thrombocytopenic purpura receiving caplacizumab need antithrombotic therapy?	7
Bempedoic Acid: a cholesterol lowering agent with a novel mechanism of action	7
Sotagliflozin and decompensated heart failure: results of the SOLOIST-WHF trial	7
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder	7
Breaking down barriers for prescribing and using hormone therapy for the treatment of menopausal symptoms: an experts’ perspective	7
Fixed-dose combination of rosuvastatin and ezetimibe: treating hypercholesteremia according to cardiovascular risk	7