OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Pharmacology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock	165
Safety assessment of propranolol for infantile hemangioma: a study in an Asian population	146
Omecamtiv Mecarbil use in systolic heart failure- Results of the GALACTIC-HF trial	42
Dasiglucagon for treating severe hypoglycemia in patients with diabetes	39
The continuum of care of anticancer treatment-induced hypothyroidism in patients with solid non-thyroid tumors: time for an intimate collaboration between oncologists and endocrinologists	37
Regional variation in longitudinal trajectories of primary care opioids prescribing across Health Boards in Scotland: a population-based study	37
Sodium-glucose co-transporter 2 inhibition and acute myocardial infarction: the DAPA-MI and EMPACT-MI trials	36
Pharmacological and clinical profile of ravulizumab 100 mg/mL formulation for paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome	34
Telmisartan (and/or nitrosamine) - induced occult melanoma: first reported case in world literature	33
Efficacy and safety of liraglutide for obesity and people who are overweight: a systematic review and meta-analysis of randomized controlled trials	30
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	29
Comparison of the relative efficacy of different biologics in different body areas in patients with moderate to severe psoriasis receiving biologics and tofacitinib in phase 3 randomized controlled tr	29
Strategies for lowering lipoprotein(a): a spotlight on novel pharmacological treatments	26
The efficacy of vitamin D in treatment of fibromyalgia: a meta-analysis of randomized controlled studies and systematic review	26
Reliance is key to effective access and oversight of medical products in case of public health emergencies	25
Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women	24
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	23
A review of recent advances in the treatment of adults with complicated urinary tract infection	23
Antimicrobial safety considerations in critically ill patients: part I: focused on acute kidney injury	23
Advances in pharmacokinetic-pharmacodynamic modelling for pediatric drug development: extrapolations and exposure-response analyses	22
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials	22
JAK inhibitors in vitiligo: what they hit and what they miss - an immunopathogenesis based exposition of existing evidence	22
Therapeutic drug monitoring of antiretroviral therapy: current progresses and future directions	22
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	22
Overcoming blinding confounds in psychedelic randomized controlled trials using biomarker driven causal mediation analysis	21

Pharmacokinetics and pharmacodynamics of Hedgehog pathway inhibitors used in the treatment of advanced or treatment-refractory basal cell carcinoma	21
Determinants of adherence to treatment in patients with ophthalmic conditions	19
Sodium-glucose cotransporter 2 inhibitors in frail, older people with type 2 diabetes and heart failure: do we have enough evidence to confidently support the use?	18
Renin angiotensin aldosterone inhibitors in the treatment of proteinuria in children with congenital anomalies of the kidney and urinary tract: more evidence needed	18
Adverse clinical outcomes associated with drug-related hospitalizations in people with dementia	18
Short-acting versus long-acting opioids for pediatric postoperative pain management	17
Comparing immunotherapies to other frequently used treatments of gastric cancer	17
Clinical outcomes of oral anticoagulant discontinuation in atrial fibrillation: a systematic review and meta-analysis	17
Pharmacological profile of once-weekly injectable semaglutide for chronic weight management	16
Psychiatric and non-psychiatric drugs causing false-positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS	16
Samidorphan for the treatment of weight gain associated with olanzapine in patients with schizophrenia and bipolar disorder	16
Past, present, and future of FGFR inhibitors in cholangiocarcinoma: from biological mechanisms to clinical applications	16
A scoping review of legibility of hand-written prescriptions and drug-orders: the writing on the wall	16
Pharmacological treatment for transforming growth factor beta induced corneal dystrophies: what is the way forward?	16
Availability and evaluation of medication management resources for carers of people with dementia: a scoping review with an environmental scan	15
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	15
Personalizing tamoxifen therapy in adjuvant therapy: a brief summary of the ongoing discussion	15
The era of lenalidomide maintenance therapy in multiple myeloma: settings for achieving best outcomes	15
Reducing potentially inappropriate polypharmacy at a national and international level: the impact of deprescribing networks	14
Do the types and routes of proton pump inhibitor treatments affect clostridium difficile in ICU patients? A retrospective cohort study	14
Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia	14
Pharmacological approaches to prevent vertical transmission of HIV and HBV	14
Sotagliflozin and decompensated heart failure: results of the SOLOIST-WHF trial	14
Prostate cancer and novel pharmacological treatment options–what’s new for 2022?	14
Genetic markers of drug hypersensitivity in pediatrics: current state and promise	13
Edoxaban for the treatment of pulmonary embolism in hospitalized COVID-19 patients	13
What is the potential for abuse of lisdexamfetamine in adults? A preclinical and clinical literature review and expert opinion	13
Review of galectin-3 inhibitors in the treatment of nonalcoholic steatohepatitis	13
Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers	13
Why is diagnosis, investigation, and improved management of kidney stone disease important? Non-pharmacological and pharmacological treatments for nephrolithiasis	13
Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study	13
Clozapine for treatment refractory catatonia in individuals with autism spectrum disorder: a retrospective chart review study	13
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life	13
Keeping up with venetoclax for leukemic malignancies: key findings, optimal regimens, and clinical considerations	13
Exploring the room for repurposed hydroxychloroquine to impede COVID-19: toxicities and multipronged combination approaches with pharmaceutical insights	13
Statin-related neurocognitive disorder: a real-world pharmacovigilance study based on the FDA adverse event reporting system	12
Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension	12
The future of pharmacology education: The Veterinary Educators in Pharmacology Special Interest Group (VEPSIG)	12
Efficacy of pharmacological agents for the management of treatment-resistant schizophrenia: a network meta-analysis	12
Updates in innovation of the treatment of pyoderma gangrenosum	11
Opioid epidemic: lessons learned and updated recommendations for misuse involving prescription versus non-prescription opioids	11
Current understanding of the etiology of cyclic vomiting syndrome and therapeutic strategies in its management	11
Clinical pharmacology of antiplatelet drugs	11
Prediction of vancomycin dose on high-dimensional data using machine learning techniques	11
Gene therapy in cardiology: pioneering a new era in medical ethics and patient care	11
Reducing the risk of death – a possible outcome in COPD patients	11
Correction	10
The use of oral GnRH antagonists to inhibit the LH surge in women undergoing ovarian stimulation for in vitro fertilization	10
Tocilizumab for the treatment of non‐critical COVID‐19 pneumonia: an overview of the rationale and clinical evidence to date	10
The effect of different contraceptive methods on the vaginal microbiome	10

A profile of delafloxacin in the treatment of adults with community-acquired bacterial pneumonia	10
Risk of new onset diabetes mellitus with pitavastatin as compared to atorvastatin and rosuvastatin: a systematic review and meta-analysis	10
Classes of drugs that target the cellular components of inflammation under clinical development for COPD	10
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	10
Proton pump inhibitors may reduce the risk of high-grade dysplasia and/or esophageal adenocarcinoma in Barrett’s esophagus: a systematic review and meta-analysis	10
Blinding and expectancy confounds in psychedelic randomized controlled trials	10
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	10
Biologics and small molecules in the management of psoriatic arthritis: Reproduction related issues in female and male patients	10
Immune checkpoint inhibition of metastatic melanoma: achieving high efficacy in the face of high toxicity	9
Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy	9
Afamelanotide for prevention of phototoxicity in erythropoietic protoporphyria	9
Safety of drugs used for the treatment of migraine during pregnancy: a narrative review	9
The association between ACE inhibitors and psoriasis based on the drug-targeted Mendelian randomization and real-world pharmacovigilance analyses	9
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	9
Considerations when prescribing opioid agonist therapies for people living with HIV	9
What is novel in the clinical management of pemphigus vulgaris?	9
Comparing the bioequivalence and safety of liraglutide in healthy Chinese subjects: an open, single-dose, randomized, repeated, two-sequence, two-cycle phase I clinical trial	8
Snakebite-associated thrombotic microangiopathy: a spotlight on pharmaceutical interventions	8
Perspectives on deprescribing in palliative care	8
STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: uptake and clinical impact	8
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	8
Response to letter to the editor: therapeutic importance of proteinuria classification in children with congenital anomalies of the kidney and urinary tract	8
Clinical considerations when switching antiretroviral therapy	8
Bempedoic Acid: a cholesterol lowering agent with a novel mechanism of action	8
Choosing the right biologic treatment for moderate-to-severe plaque psoriasis: the impact of comorbidities	8
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective, and interventions to suppor	8
Immunotherapy for the treatment of metastatic small cell lung cancer: Focus on pembrolizumab	7
Intravitreal immunotherapy in non-infectious uveitis: an update	7
The effect of vitamin D supplementation on glycemic status of elderly people with prediabetes: a 12-month open-label, randomized-controlled study	7
Telmisartan/hydrochlorothiazide-induced nevus-associated cutaneous melanoma: first report in the medical literature	7
The outcomes of goal-oriented medication reviews for the elderly: current research and future directions	7
Pharmacokinetic/pharmacodynamic target attainment in critically ill renal patients on antimicrobial usage: focus on novel beta-lactams and beta lactams/beta-lactamase inhibitors	7
Novel and emerging treatment strategies for lupus nephritis	7
Do patients with immune-mediated thrombotic thrombocytopenic purpura receiving caplacizumab need antithrombotic therapy?	7
Targeting the spectrum of immune checkpoints in prostate cancer	7
Broadening access to tenofovir alafenamide for the treatment and prevention of HIV-1 infection	7
Parametric population pharmacokinetics of isoniazid: a systematic review	7
Biosimilar and generic formulations of novel antidiabetic drugs: the role of liraglutide in clinical pharmacology of type 2 diabetes	7
Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials	7
The pharmacotherapeutics of sarcoidosis	7
Effects of anti-diabetic treatments in type 2 diabetes and fatty liver disease	7
A comprehensive strategy to address shortage of Erwinia asparaginase in pediatric acute lymphoblastic leukemia	7
Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes	7
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations	7
Compounds of plants with activity against SARS-CoV-2 targets	6
Prescription patterns of antiseizure drugs in tuberous sclerosis complex (TSC)-associated epilepsy: a multicenter cohort study from Germany and review of the literature	6
The impact of body composition on treatment in ovarian cancer: a current insight	6
Pharmacotherapy of LAMA/LABA inhaled therapy combinations for chronic obstructive pulmonary disease: a clinical overview	6
Hugan tablets for the treatment of RUCAM based drug-induced liver injury: a propensity score matching analysis using a nationwide database	6
Update on drug interactions with non-vitamin-K-antagonist oral anticoagulants for stroke prevention in elderly patients	6
Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants	6
Optimizing ganciclovir and valganciclovir dosing regimens in pediatric patients with cytomegalovirus infection: a spotlight on therapeutic drug monitoring	6
Colony stimulating factors for prophylaxis of chemotherapy-induced neutropenia in children	6
Dostarlimab for the treatment of advanced endometrial cancer	6
Emapalumab for adult and pediatric patients with hemophagocytic lymphohistiocytosis	6
Givosiran for the treatment of acute hepatic porphyria	6
Growing role of SGLT2i in heart failure: evidence from clinical trials	6
Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study	6
Epoprostenol for the treatment of pulmonary arterial hypertension	6
Predicting plasma concentration of quetiapine in patients with depression using machine learning techniques based on real-world evidence	6