OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Pharmacology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence	139
Blinding and expectancy confounds in psychedelic randomized controlled trials	116
Contraception and reproductive planning during the COVID-19 pandemic	71
The use of isotretinoin for acne – an update on optimal dosing, surveillance, and adverse effects	58
Pharmacological Management of Postmenopausal Osteoporosis: a Level I Evidence Based - Expert Opinion	49
Rapid review of suspected adverse drug events due to remdesivir in the WHO database; findings and implications	42
Integrating psychotherapy and psychopharmacology: psychedelic-assisted psychotherapy and other combined treatments	40
Pathophysiology, diagnosis, and pharmacological treatment of prurigo nodularis	39
An update on the clinical pharmacology of methylphenidate: therapeutic efficacy, abuse potential and future considerations	37
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	33
Molecular docking and dynamics study to explore phytochemical ligand molecules against the main protease of SARS-CoV-2 from extensive phytochemical datasets	31
Pharmacokinetic/pharmacodynamic target attainment in critically ill renal patients on antimicrobial usage: focus on novel beta-lactams and beta lactams/beta-lactamase inhibitors	31
Switching biologics in psoriasis - practical guidance and evidence to support	30
An update on the complex relationship between clozapine and pneumonia	30
Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress	29
Update on the effects of GLP-1 receptor agonists for the treatment of polycystic ovary syndrome	28
Genetic testing in patients undergoing percutaneous coronary intervention: rationale, evidence and practical recommendations	27
Clozapine-related drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a systematic review	27
Clinical pharmacology and PK/PD translation of the second-generation Bruton’s tyrosine kinase inhibitor, zanubrutinib	26
Prediction of vancomycin dose on high-dimensional data using machine learning techniques	26
Review of galectin-3 inhibitors in the treatment of nonalcoholic steatohepatitis	25
The potential role of interventions impacting on gut-microbiota in epilepsy	25
Strategies for recombinant production of antimicrobial peptides with pharmacological potential	24
Prevention of colistin induced nephrotoxicity: a review of preclinical and clinical data	23
Afamelanotide for prevention of phototoxicity in erythropoietic protoporphyria	23

An update on drug development for the treatment of nonalcoholic fatty liver disease – from ongoing clinical trials to future therapy	21
Pathophysiology, diagnosis, and pharmacological treatment of gastro-esophageal reflux disease	21
Omega-3 polyunsaturated fatty acids focusing on eicosapentaenoic acid and docosahexaenoic acid in the prevention of cardiovascular diseases: a review of the state-of-the-art	21
Novel therapies for AML: a round-up for clinicians	21
The Role of testosterone treatment in patients with metabolic disorders	20
UK Medical Cannabis Registry: an analysis of clinical outcomes of medicinal cannabis therapy for generalized anxiety disorder	20
UK Medical Cannabis registry: an analysis of clinical outcomes of medicinal cannabis therapy for chronic pain conditions	20
Who is blind in psychedelic research? Letter to the editor regarding: blinding and expectancy confounds in psychedelic randomized controlled trials	19
Melatonin as a putative protection against myocardial injury in COVID-19 infection	19
Estetrol (E4): the new estrogenic component of combined oral contraceptives	18
Serious adverse events and deaths in PCSK9 inhibitor trials reported on ClinicalTrials.gov: a systematic review	18
Hippocampal volume, function, and related molecular activity in anorexia nervosa: A scoping review	18
Prevalence of polymorphisms in thiopurine metabolism and association with adverse outcomes: a South Asian region-specific systematic review and meta-analysis	18
SARS-CoV-2 protein drug targets landscape: a potential pharmacological insight view for the new drug development	18
Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis	18
β-blocker therapy for infantile hemangioma	17
Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women	17
Pharmacological control of pain during propofol injection: a systematic review and meta-analysis	17
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	17
Sex differences in COPD management	16
Induction and maintenance of procedural sedation in adults: focus on remimazolam injection	16
Drug delivery and targeting to brain tumors: considerations for crossing the blood-brain barrier	15
Drospirenone 4 mg-only pill (DOP) in 24+4 regimen: a new option for oral contraception	15
Pharmacologic management ofMycobacterium ulceransinfection	15
Safety and efficacy of therapies for chylomicronemia	15
Patiromer for the treatment of hyperkalemia	14
Detection of mobile colistin-resistance gene variants (mcr-1andmcr-2) in urinary tract pathogens in Bangladesh: the last resort of infectious disease management colistin efficacy is unde	14
The management of anti-infective agents in intensive care units: the potential role of a ‘fast’ pharmacology	14
Recent advances and future perspectives in the pharmacological treatment ofCandida aurisinfections	14
Clinical pharmacology of antiplatelet drugs	14
Update on diagnosis and treatment of immune thrombocytopenia	13
Tedizolid (torezolid) for the treatment of complicated skin and skin structure infections	13
Adverse events associated with nilotinib in chronic myeloid leukemia: mechanisms and management strategies	13
The pharmacology of antibiotic therapy in hidradenitis suppurativa	13
Remdesivir emergency approvals: a comparison of the U.S., Japanese, and EU systems	13
Glucocorticoids in rheumatoid arthritis: the silent companion in the therapeutic strategy	13
Clinical trials with plants in diabetes mellitus therapy: a systematic review	13
Dostarlimab for the treatment of advanced endometrial cancer	13
Selective FGFR/FGF pathway inhibitors: inhibition strategies, clinical activities, resistance mutations, and future directions	13
Initial dosage optimization of tacrolimus in Chinese pediatric patients undergoing kidney transplantation based on population pharmacokinetics and pharmacogenetics	13
Vaccination and their importance for lung transplant recipients in a COVID-19 world	13
The protective effect of tanshinone IIa on endothelial cells: a generalist among clinical therapeutics	13
How can we improve the safe use of herbal medicine and other natural products? A clinical pharmacologist mission	12
Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials	12
Targeting the spectrum of immune checkpoints in prostate cancer	12
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	12
How do nocebo effects in placebo groups of randomized controlled trials provide a possible explicative framework for the COVID-19 pandemic?	12
Prescription patterns of antiseizure drugs in tuberous sclerosis complex (TSC)-associated epilepsy: a multicenter cohort study from Germany and review of the literature	12
Methotrexate and cardiovascular risk in rheumatic diseases:A comprehensive review	12
Finerenone: a mineralocorticoid receptor antagonist for the treatment of chronic kidney disease associated with type 2 diabetes	12

How polypharmacy affects frailty	12
Opioid epidemic: lessons learned and updated recommendations for misuse involving prescription versus non-prescription opioids	12
The role of PCSK9 in NAFLD/NASH and therapeutic implications of PCSK9 inhibition	11
Population pharmacokinetics of oxcarbazepine: a systematic review	11
The impact of body composition on treatment in ovarian cancer: a current insight	11
Patient initiation and maintenance of GLP-1 RAs for treatment of obesity	11
Current perspective on fibrinogen concentrate in critical bleeding	10
The effect of different contraceptive methods on the vaginal microbiome	10
Overview of the clinical use of erdafitinib as a treatment option for the metastatic urothelial carcinoma: where do we stand	10
Opioids for chronic low back pain management: a Bayesian network meta-analysis	10
Combining hydroxychloroquine and minocycline: potential role in moderate to severe COVID-19 infection	10
Current status and prospects of IL-6–targeting therapy	10
Paracetamol for low back pain: the state of the research field	10
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life	10
Copanlisib for the treatment of adults with relapsed follicular lymphoma	10
Recent advances in clearance monitoring of monoclonal antibodies in patients with inflammatory bowel diseases	10
Treatment of infections in cancer patients: an update from the neutropenia, infection and myelosuppression study group of the Multinational Association for Supportive Care in Cancer (MASCC)	9
Cannabinoids and drug metabolizing enzymes: potential for drug-drug interactions and implications for drug safety and efficacy	9
Radical metastasectomy followed by sorafenib versus observation in patients withclear cell renal cell carcinoma: extended follow -up of efficacy results from the randomized phase II RESORT trial	9
Givosiran for the treatment of acute hepatic porphyria	9
The effect of tramadol on blood glucose concentrations: a systematic review	9
Optimizing de-escalation of inhaled corticosteroids in COPD: a systematic review of real-world findings	9
Assessing the potential for drug interactions and long term safety of melatonin for the treatment of insomnia in children with autism spectrum disorder	9
Antibody–drug conjugates for previously treated aggressive lymphomas: focus on polatuzumab vedotin	9
The new European guidelines for prevention of cardiovascular disease are misleading	9
The value of deprescribing in older adults with dementia: a narrative review	9
Novel pharmacological therapies for the treatment of endometriosis	9
Efficacy and safety of injectable deoxycholic acid for submental fat reduction: a systematic review and meta-analysis of randomized controlled trials	9
The changes of serum zinc, copper, and selenium levels in epileptic patients: a systematic review and meta-analysis	9
Effects of metformin on body weight in polycystic ovary syndrome patients: model-based meta-analysis	8
Quantitative efficacy of L-carnitine supplementation on glycemic control in type 2 diabetes mellitus patients	8
Growing role of SGLT2i in heart failure: evidence from clinical trials	8
Classes of drugs that target the cellular components of inflammation under clinical development for COPD	8
Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	8
Perspectives on the pharmacological management of psoriasis in pediatric and adolescent patients	8
Thromboembolic Risk of C1 Esterase Inhibitors: A Systematic Review on Current Evidence	8
Profiles of polypharmacy in older adults and medication associations with signs of aspiration	8
Cannabidiol drug interaction considerations for prescribers and pharmacists	8
Biologic and advanced immunomodulating therapeutic options for sarcoidosis: a clinical update	8
Checkpoint inhibitor immunotherapy for glioblastoma: current progress, challenges and future outlook	8
The effect of inhaled corticosteroids on the outcomes of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials	8
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	8
Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations	8
The clinical pharmacology of the medical treatment for overactive bladder in adults	8
Semaglutide injection for the treatment of adults with type 2 diabetes	8
Guiding principles for the use of knowledge bases and real-world data in clinical decision support systems: report by an international expert workshop at Karolinska Institutet	8
Aminoadamantanes: from treatment of Parkinson’s and Alzheimer’s disease to symptom amelioration of long COVID-19 syndrome?	8
Treatment options following metformin in primary prevention populations with type 2 diabetes: which is the right road to take?	8
Clinical efficacy and safety of apatinib as maintenance treatment in patients with advanced esophageal squamous cell carcinoma	8
The role of triple therapy in the management of COPD	7
Cannabidiol in low back pain: scientific rationale for clinical trials in low back pain	7
WHO collaborative registration procedure using stringent regulatory authorities’ medicine evaluation: reliance in action?	7
Favipiravir-based treatment for outcomes of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials	7
Fixed-dose combination of rosuvastatin and ezetimibe: treating hypercholesteremia according to cardiovascular risk	7
Do patients with immune-mediated thrombotic thrombocytopenic purpura receiving caplacizumab need antithrombotic therapy?	7
Effect of Perioperative Ketamine on Postoperative Mood and Depression: A Review of the Literature	7
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	7
Clinical pharmacological innovation in the treatment of depression	7
Dose discordance of direct acting oral anticoagulants using different equations for estimating GFR: a literature review	7
RETRACTED ARTICLE:Fetal safety of medications used in treating infertility	7
Treatment options for children with multi-drug resistant tuberculosis	7
Cabozantinib as a second-line treatment option in hepatocellular carcinoma	7
Emapalumab for adult and pediatric patients with hemophagocytic lymphohistiocytosis	7
Anti-nerve growth factor antibodies for the treatment of low back pain	7
An update on guanylyl cyclase C in the diagnosis, chemoprevention, and treatment of colorectal cancer	7
Clinical pharmacology of siRNA therapeutics: current status and future prospects	7
How to handle the delayed or missed dose of rivaroxaban in patients with non-valvular atrial fibrillation: model-informed remedial dosing	7
Peyronie’s disease: pharmacological treatments and limitations	7
Tenapanor for the treatment of irritable bowel syndrome with constipation	7
pre-existing diabetes and PTDM in kidney transplant recipients: how to handle immunosuppression	7
The crosstalk between antiretrovirals pharmacology and HIV drug resistance	7
Compounds of plants with activity against SARS-CoV-2 targets	7