Expert Review of Clinical Pharmacology

Article	Citations
Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence	137
Blinding and expectancy confounds in psychedelic randomized controlled trials	111
Cancer prevention and treatment using combination therapy with natural compounds	87
Contraception and reproductive planning during the COVID-19 pandemic	71
The use of isotretinoin for acne – an update on optimal dosing, surveillance, and adverse effects	57
Pharmacological Management of Postmenopausal Osteoporosis: a Level I Evidence Based - Expert Opinion	48
Rapid review of suspected adverse drug events due to remdesivir in the WHO database; findings and implications	42
Integrating psychotherapy and psychopharmacology: psychedelic-assisted psychotherapy and other combined treatments	39
Pathophysiology, diagnosis, and pharmacological treatment of prurigo nodularis	38
An update on the clinical pharmacology of methylphenidate: therapeutic efficacy, abuse potential and future considerations	37
The ‘entourage effect’ or ‘hodge-podge hashish’: the questionable rebranding, marketing, and expectations of cannabis polypharmacy	34
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	33
Pharmacokinetic/pharmacodynamic target attainment in critically ill renal patients on antimicrobial usage: focus on novel beta-lactams and beta lactams/beta-lactamase inhibitors	31
Molecular docking and dynamics study to explore phytochemical ligand molecules against the main protease of SARS-CoV-2 from extensive phytochemical datasets	30
An update on the complex relationship between clozapine and pneumonia	30
Switching biologics in psoriasis - practical guidance and evidence to support	28
Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress	28
Update on the effects of GLP-1 receptor agonists for the treatment of polycystic ovary syndrome	27
Genetic testing in patients undergoing percutaneous coronary intervention: rationale, evidence and practical recommendations	27
Clozapine-related drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a systematic review	26
Review of galectin-3 inhibitors in the treatment of nonalcoholic steatohepatitis	25
Clinical pharmacology and PK/PD translation of the second-generation Bruton’s tyrosine kinase inhibitor, zanubrutinib	25
Prediction of vancomycin dose on high-dimensional data using machine learning techniques	25
The potential role of interventions impacting on gut-microbiota in epilepsy	24
Prevention of colistin induced nephrotoxicity: a review of preclinical and clinical data	22

Afamelanotide for prevention of phototoxicity in erythropoietic protoporphyria	22
Strategies for recombinant production of antimicrobial peptides with pharmacological potential	22
Omega-3 polyunsaturated fatty acids focusing on eicosapentaenoic acid and docosahexaenoic acid in the prevention of cardiovascular diseases: a review of the state-of-the-art	21
The Role of testosterone treatment in patients with metabolic disorders	20
UK Medical Cannabis registry: an analysis of clinical outcomes of medicinal cannabis therapy for chronic pain conditions	20
An update on drug development for the treatment of nonalcoholic fatty liver disease – from ongoing clinical trials to future therapy	20
Pathophysiology, diagnosis, and pharmacological treatment of gastro-esophageal reflux disease	20
UK Medical Cannabis Registry: an analysis of clinical outcomes of medicinal cannabis therapy for generalized anxiety disorder	20
Who is blind in psychedelic research? Letter to the editor regarding: blinding and expectancy confounds in psychedelic randomized controlled trials	19
Novel therapies for AML: a round-up for clinicians	19
Melatonin as a putative protection against myocardial injury in COVID-19 infection	19
Prevalence of polymorphisms in thiopurine metabolism and association with adverse outcomes: a South Asian region-specific systematic review and meta-analysis	18
Serious adverse events and deaths in PCSK9 inhibitor trials reported on ClinicalTrials.gov: a systematic review	18
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	17
Hippocampal volume, function, and related molecular activity in anorexia nervosa: A scoping review	17
Estetrol (E4): the new estrogenic component of combined oral contraceptives	17
SARS-CoV-2 protein drug targets landscape: a potential pharmacological insight view for the new drug development	17
The role of xenobiotic-metabolizing enzymes in the placenta: a growing research field	17
β-blocker therapy for infantile hemangioma	17
Pharmacological control of pain during propofol injection: a systematic review and meta-analysis	17
Sex differences in COPD management	16
Induction and maintenance of procedural sedation in adults: focus on remimazolam injection	16
Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis	16
Drospirenone 4 mg-only pill (DOP) in 24+4 regimen: a new option for oral contraception	15
Drug delivery and targeting to brain tumors: considerations for crossing the blood-brain barrier	15
Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women	15
Pharmacologic management ofMycobacterium ulceransinfection	15
Incidence and risk of proteinuria associated with newly approved vascular endothelial growth factor receptor tyrosine kinase inhibitors in cancer patients: an up-to-date meta-analysis of randomized co	14
Clinical pharmacology of antiplatelet drugs	14
Safety and efficacy of therapies for chylomicronemia	14
Detection of mobile colistin-resistance gene variants (mcr-1andmcr-2) in urinary tract pathogens in Bangladesh: the last resort of infectious disease management colistin efficacy is unde	14
The management of anti-infective agents in intensive care units: the potential role of a ‘fast’ pharmacology	14
Remdesivir emergency approvals: a comparison of the U.S., Japanese, and EU systems	13
Adverse events associated with nilotinib in chronic myeloid leukemia: mechanisms and management strategies	13
Clinical trials with plants in diabetes mellitus therapy: a systematic review	13
Dostarlimab for the treatment of advanced endometrial cancer	13
Tedizolid (torezolid) for the treatment of complicated skin and skin structure infections	13
Selective FGFR/FGF pathway inhibitors: inhibition strategies, clinical activities, resistance mutations, and future directions	13
Patiromer for the treatment of hyperkalemia	13
Vaccination and their importance for lung transplant recipients in a COVID-19 world	13
The protective effect of tanshinone IIa on endothelial cells: a generalist among clinical therapeutics	13
Glucocorticoids in rheumatoid arthritis: the silent companion in the therapeutic strategy	13
Initial dosage optimization of tacrolimus in Chinese pediatric patients undergoing kidney transplantation based on population pharmacokinetics and pharmacogenetics	13
Recent advances and future perspectives in the pharmacological treatment ofCandida aurisinfections	13
The pharmacology of antibiotic therapy in hidradenitis suppurativa	13
Opioid epidemic: lessons learned and updated recommendations for misuse involving prescription versus non-prescription opioids	12
How can we improve the safe use of herbal medicine and other natural products? A clinical pharmacologist mission	12
Finerenone: a mineralocorticoid receptor antagonist for the treatment of chronic kidney disease associated with type 2 diabetes	12
Targeting the spectrum of immune checkpoints in prostate cancer	12
Methotrexate and cardiovascular risk in rheumatic diseases:A comprehensive review	12

Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials	12
Prescription patterns of antiseizure drugs in tuberous sclerosis complex (TSC)-associated epilepsy: a multicenter cohort study from Germany and review of the literature	12
Update on diagnosis and treatment of immune thrombocytopenia	12
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	12
How do nocebo effects in placebo groups of randomized controlled trials provide a possible explicative framework for the COVID-19 pandemic?	12
Patient initiation and maintenance of GLP-1 RAs for treatment of obesity	11
The impact of body composition on treatment in ovarian cancer: a current insight	11
The role of PCSK9 in NAFLD/NASH and therapeutic implications of PCSK9 inhibition	11
Evolution of the inclusion/exclusion criteria and primary endpoints in pivotal trials of biologics and small oral molecules for the treatment of psoriasis	11
Risk of acute pancreatitis with incretin-based therapy: a systematic review and updated meta-analysis of cardiovascular outcomes trials	11
How polypharmacy affects frailty	11
Copanlisib for the treatment of adults with relapsed follicular lymphoma	10
Combining hydroxychloroquine and minocycline: potential role in moderate to severe COVID-19 infection	10
Current perspective on fibrinogen concentrate in critical bleeding	10
Recent advances in clearance monitoring of monoclonal antibodies in patients with inflammatory bowel diseases	10
Paracetamol for low back pain: the state of the research field	10
The effect of different contraceptive methods on the vaginal microbiome	10
Overview of the clinical use of erdafitinib as a treatment option for the metastatic urothelial carcinoma: where do we stand	10
Opioids for chronic low back pain management: a Bayesian network meta-analysis	10
The effect of tramadol on blood glucose concentrations: a systematic review	9
Optimizing de-escalation of inhaled corticosteroids in COPD: a systematic review of real-world findings	9
Efficacy and safety of injectable deoxycholic acid for submental fat reduction: a systematic review and meta-analysis of randomized controlled trials	9
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life	9
The value of deprescribing in older adults with dementia: a narrative review	9
Novel pharmacological therapies for the treatment of endometriosis	9
Givosiran for the treatment of acute hepatic porphyria	9
The changes of serum zinc, copper, and selenium levels in epileptic patients: a systematic review and meta-analysis	9
Population pharmacokinetics of oxcarbazepine: a systematic review	9
Current status and prospects of IL-6–targeting therapy	9
Antibody–drug conjugates for previously treated aggressive lymphomas: focus on polatuzumab vedotin	9
The new European guidelines for prevention of cardiovascular disease are misleading	8
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	8
Thromboembolic Risk of C1 Esterase Inhibitors: A Systematic Review on Current Evidence	8
Cannabinoids and drug metabolizing enzymes: potential for drug-drug interactions and implications for drug safety and efficacy	8
Radical metastasectomy followed by sorafenib versus observation in patients withclear cell renal cell carcinoma: extended follow -up of efficacy results from the randomized phase II RESORT trial	8
Growing role of SGLT2i in heart failure: evidence from clinical trials	8
Checkpoint inhibitor immunotherapy for glioblastoma: current progress, challenges and future outlook	8
The effect of inhaled corticosteroids on the outcomes of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials	8
Treatment options following metformin in primary prevention populations with type 2 diabetes: which is the right road to take?	8
Treatment of infections in cancer patients: an update from the neutropenia, infection and myelosuppression study group of the Multinational Association for Supportive Care in Cancer (MASCC)	8
Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations	8
Profiles of polypharmacy in older adults and medication associations with signs of aspiration	8
Assessing the potential for drug interactions and long term safety of melatonin for the treatment of insomnia in children with autism spectrum disorder	8
Guiding principles for the use of knowledge bases and real-world data in clinical decision support systems: report by an international expert workshop at Karolinska Institutet	8
Classes of drugs that target the cellular components of inflammation under clinical development for COPD	8
Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	8
Perspectives on the pharmacological management of psoriasis in pediatric and adolescent patients	8
Clinical efficacy and safety of apatinib as maintenance treatment in patients with advanced esophageal squamous cell carcinoma	8
Effects of metformin on body weight in polycystic ovary syndrome patients: model-based meta-analysis	8
The clinical pharmacology of the medical treatment for overactive bladder in adults	8
Quantitative efficacy of L-carnitine supplementation on glycemic control in type 2 diabetes mellitus patients	8
Biologic and advanced immunomodulating therapeutic options for sarcoidosis: a clinical update	8
Treatment options for children with multi-drug resistant tuberculosis	7
Emapalumab for adult and pediatric patients with hemophagocytic lymphohistiocytosis	7
Anti-nerve growth factor antibodies for the treatment of low back pain	7
An update on guanylyl cyclase C in the diagnosis, chemoprevention, and treatment of colorectal cancer	7
The role of triple therapy in the management of COPD	7
WHO collaborative registration procedure using stringent regulatory authorities’ medicine evaluation: reliance in action?	7
Favipiravir-based treatment for outcomes of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials	7
Cabozantinib as a second-line treatment option in hepatocellular carcinoma	7
The crosstalk between antiretrovirals pharmacology and HIV drug resistance	7
Compounds of plants with activity against SARS-CoV-2 targets	7
Cannabidiol in low back pain: scientific rationale for clinical trials in low back pain	7
RETRACTED ARTICLE:Fetal safety of medications used in treating infertility	7
Tenapanor for the treatment of irritable bowel syndrome with constipation	7
Do patients with immune-mediated thrombotic thrombocytopenic purpura receiving caplacizumab need antithrombotic therapy?	7
Effect of Perioperative Ketamine on Postoperative Mood and Depression: A Review of the Literature	7
Semaglutide injection for the treatment of adults with type 2 diabetes	7
How to handle the delayed or missed dose of rivaroxaban in patients with non-valvular atrial fibrillation: model-informed remedial dosing	7
Peyronie’s disease: pharmacological treatments and limitations	7
The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack	6
Dose discordance of direct acting oral anticoagulants using different equations for estimating GFR: a literature review	6
Obesity decreases the EC50 of epidural ropivacaine when combined with dexmedetomidine for labor analgesia	6
Appropriate chemopreventive strategy for anti-tubercular therapy related liver injury is unsettled: Results from a systematic review and network meta-analysis	6
Lenvatinib: established and promising drug for the treatment of advanced hepatocellular carcinoma	6
Can the microbiota predict response to systemic cancer therapy, surgical outcomes, and survival? The answer is in the gut	6
Immunogenicity-unwanted immune responses to biological drugs – can we predict them?	6
Pexidartinib for the treatment of adult symptomatic patients with tenosynovial giant cell tumors	6
Clinical pharmacology of siRNA therapeutics: current status and future prospects	6
Prognostic factors of good response to DMARDs in psoriatic arthritis: a narrative review	6

Comparing quality of life outcomes of JAK inhibitors and biological treatments for atopic dermatitis: a systematic review and network meta-analysis	6
Characteristics and clinical influence factors of arsenic species in plasma and their role of arsenic species as predictors for clinical efficacy in acute promyelocytic leukemia (APL) patients treated	6
Insights into real-world treatment of cluster headache through a large Italian database: prevalence, prescription patterns, and costs	6
Fixed-dose combination of rosuvastatin and ezetimibe: treating hypercholesteremia according to cardiovascular risk	6
Effects of anti-diabetic treatments in type 2 diabetes and fatty liver disease	6
Epoprostenol for the treatment of pulmonary arterial hypertension	6
Antiviral therapy for the sexually transmitted viruses: recent updates on vaccine development	6
Efficacy and safety of liraglutide for obesity and people who are overweight: a systematic review and meta-analysis of randomized controlled trials	6
Aminoadamantanes: from treatment of Parkinson’s and Alzheimer’s disease to symptom amelioration of long COVID-19 syndrome?	6
Medication therapy strategies for the coronavirus disease 2019 (COVID-19): recent progress and challenges	6
A dermatologist perspective in the pharmacological treatment of patients with psoriasis and psoriatic arthritis	6
Cluster headache therapies: pharmacology and mode of action	6
Modern approaches for the phenotyping of cytochrome P450 enzymes in children	6
Reliance: a smarter way of regulating medical products - The IPRP survey	6
Cenobamate tablets as a treatment for focal-onset seizures in adults	6
Clinical course of severe patients with COVID-19 treated with tocilizumab: report from a cohort study in Spain	6
Cannabidiol drug interaction considerations for prescribers and pharmacists	6
Sotagliflozin and decompensated heart failure: results of the SOLOIST-WHF trial	6
A narrative review of buprenorphine in adult cancer pain	6
Clinical pharmacological innovation in the treatment of depression	6
A pharmacological profile of intravenous amisulpride for the treatment of postoperative nausea and vomiting	6
Non-vitamin K antagonist oral anticoagulants for stroke prevention in atrial fibrillation: safety issues in the elderly	5
Pharmaceuticals agents for preventing NSAID-induced gastric ulcers: a patent review	5
Incidence and risk of severe adverse events associated with trastuzumab emtansine (T-DM1) in the treatment of breast cancer: an up-to-date systematic review and meta-analysis of randomized controlled	5
Novel and emerging treatment strategies for lupus nephritis	5
The availability of new drugs for hemophilia treatment	5
Edoxaban for the treatment of pulmonary embolism in hospitalized COVID-19 patients	5
Real-world effectiveness of olanzapine and risperidone in the treatment of schizophrenia in Brazil over a 16-year follow-up period; findings and implications	5
Management of overdoses of salvia, kratom, and psilocybin mushrooms: a literature review	5
Pharmacological management of cardiovascular risk in chronic inflammatory rheumatic diseases	5
Population pharmacokinetics of omeprazole in obese and normal-weight adults	5
Therapeutic approach to difficult-to-treat typical absences and related epilepsy syndromes	5
The paradigm of norgestimate: a third-generation testosterone-derivative progestin with a peripheral anti-androgenic activity and the lowest risk of venous thromboembolism	5
Pharmacological management of fibromyalgia: a Bayesian network meta-analysis	5
Oral acetazolamide for intraocular pressure lowering: balancing efficacy and safety in ophthalmic practice	5
Telmisartan/hydrochlorothiazide-induced nevus-associated cutaneous melanoma: first report in the medical literature	5
Reliance is key to effective access and oversight of medical products in case of public health emergencies	5
Could a specific ACE2 activator drug improve the clinical outcome of SARS-CoV-2? A potential pharmacological insight	5
Immunotherapy of High Risk Non-Muscle Invasive Bladder Cancer	5
Recent advances in the pharmacological management of sepsis-associated acute kidney injury	5
Use of calcium channel blockers in dermatology: a narrative review	5
Peroxisome proliferator-activated receptor-gamma (PPARγ) and its immunomodulation function: current understanding and future therapeutic implications	5
Clinical pharmacology of SGLT-2 inhibitors in heart failure	5
Time course and dose effect of metformin on weight in patients with different disease states	5
Effect of laparoscopic sleeve gastrectomy on drug pharmacokinetics	5
Tumor mutational burden as a tissue-agnostic biomarker for cancer immunotherapy	5
Bempedoic Acid: a cholesterol lowering agent with a novel mechanism of action	5
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	5
Proton pump inhibitors may reduce the risk of high-grade dysplasia and/or esophageal adenocarcinoma in Barrett’s esophagus: a systematic review and meta-analysis	5
Age and psoriatic arthritis are important predictors of biologic agent switch in psoriasis	5
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder	5
Treatment challenges in adult female acne and future directions	5
The association between the use of sodium glucose cotransporter 2 inhibitor and the risk of diabetic retinopathy and other eye disorders: a systematic review and meta-analysis	5
Hematological toxicities associated with linezolid therapy in adults: key findings and clinical considerations	4
BNT162b2 mRNA COVID-19 vaccine is safe in a setting of patients on biologic therapy with inflammatory bowel diseases: a monocentric real-life study	4
The coincidence of increased risk of atrial fibrillation in randomized control trials of omega-3 fatty acids: a meta-analysis	4
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	4
Why is diagnosis, investigation, and improved management of kidney stone disease important? Non-pharmacological and pharmacological treatments for nephrolithiasis	4
Effects of progestin-only contraceptives on the endometrium	4
The efficacy of vitamin D in treatment of fibromyalgia: a meta-analysis of randomized controlled studies and systematic review	4
Saliva for Model Informed Precision Dosing	4
Spotlight on experiences of medicine unavailability: access to medicines challenges for NCDs and NTDs - the contrasting cases of insulin and praziquantel	4
Splicing deregulation, microRNA and notch aberrations: fighting the three-headed dog to overcome drug resistance in malignant mesothelioma	4
Interactions of antiepileptic drugs with drugs approved for the treatment of indications other than epilepsy	4
Nephroprotective effects of febuxostat and/or mirtazapine against gentamicin-induced nephrotoxicity through modulation of ERK 1/2, NF-κB and MCP1	4
BMI but not age and sex negatively impact on the outcome of pharmacotherapy in fibromyalgia: a systematic review	4
Ibuprofen and postoperative bleeding in children undergoing tonsillectomy or adenotonsillectomy: a systematic review and meta-analysis of randomized clinical trials.	4
Update on drug interactions with non-vitamin-K-antagonist oral anticoagulants for stroke prevention in elderly patients	4
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	4
Tocilizumab for the treatment of non‐critical COVID‐19 pneumonia: an overview of the rationale and clinical evidence to date	4
Current immunosuppressive and antifibrotic therapies of systemic sclerosis and emerging therapeutic strategies	4
Potential clinical applications of Ashwagandha (Withania somnifera) in medicine and neuropsychiatry	4
Effectiveness of polyene phosphatidylcholine and its combination with other drugs in patients with liver diseases based on real-world research	4
The role of the alternative pathway in paroxysmal nocturnal hemoglobinuria and emerging treatments	4
Pharmacological and clinical profile of cefiderocol, a siderophore cephalosporin against gram-negative pathogens	4
The potential role of big data in the detection of adverse drug reactions	4
pre-existing diabetes and PTDM in kidney transplant recipients: how to handle immunosuppression	4
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	4
Pharmacological profile of once-weekly injectable semaglutide for chronic weight management	4
Is single versus combination therapy problematic in the treatment of cutaneous melanoma?	4
Prevalence and characteristics of South African treatment-seeking patients with substance use disorder and co-occurring attention-deficit/hyperactivity disorder	4
Designer benzodiazepines: an update	4
Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities	4
Hugan tablets for the treatment of RUCAM based drug-induced liver injury: a propensity score matching analysis using a nationwide database	3
Exploring the effectiveness of incorporating carbon nanotubes into bioengineered scaffolds to improve cardiomyocyte function	3
Exploring the room for repurposed hydroxychloroquine to impede COVID-19: toxicities and multipronged combination approaches with pharmaceutical insights	3
Biologics and small molecules in the management of psoriatic arthritis: Reproduction related issues in female and male patients	3
Published population pharmacokinetic models of valproic acid in adult patients: a systematic review and external validation in a Chinese sample of inpatients with bipolar disorder	3
Treatment of heterozygous familial hypercholesterolemia: what does the future hold?	3
Keeping up with venetoclax for leukemic malignancies: key findings, optimal regimens, and clinical considerations	3
Safety assessment of propranolol for infantile hemangioma: a study in an Asian population	3
The effect of vitamin D supplementation on glycemic status of elderly people with prediabetes: a 12-month open-label, randomized-controlled study	3
Development and progress of clinical trials of Coronavirus Disease 2019 antiviral drugs	3
Comparison of the relative efficacy of different biologics in different body areas in patients with moderate to severe psoriasis receiving biologics and tofacitinib in phase 3 randomized controlled tr	3
Telmisartan (and/or nitrosamine) - induced occult melanoma: first reported case in world literature	3