Expert Review of Clinical Pharmacology

Article	Citations
Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence	165
Blinding and expectancy confounds in psychedelic randomized controlled trials	146
Pharmacological Management of Postmenopausal Osteoporosis: a Level I Evidence Based - Expert Opinion	65
Rapid review of suspected adverse drug events due to remdesivir in the WHO database; findings and implications	46
Pathophysiology, diagnosis, and pharmacological treatment of prurigo nodularis	45
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	42
Molecular docking and dynamics study to explore phytochemical ligand molecules against the main protease of SARS-CoV-2 from extensive phytochemical datasets	37
Clinical pharmacology and PK/PD translation of the second-generation Bruton’s tyrosine kinase inhibitor, zanubrutinib	36
Update on the effects of GLP-1 receptor agonists for the treatment of polycystic ovary syndrome	34
Pharmacokinetic/pharmacodynamic target attainment in critically ill renal patients on antimicrobial usage: focus on novel beta-lactams and beta lactams/beta-lactamase inhibitors	34
An update on the complex relationship between clozapine and pneumonia	34
Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress	34
Genetic testing in patients undergoing percutaneous coronary intervention: rationale, evidence and practical recommendations	33
Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis	30
Prediction of vancomycin dose on high-dimensional data using machine learning techniques	29
Review of galectin-3 inhibitors in the treatment of nonalcoholic steatohepatitis	29
Omega-3 polyunsaturated fatty acids focusing on eicosapentaenoic acid and docosahexaenoic acid in the prevention of cardiovascular diseases: a review of the state-of-the-art	27
Afamelanotide for prevention of phototoxicity in erythropoietic protoporphyria	26
The Role of testosterone treatment in patients with metabolic disorders	26
Prevention of colistin induced nephrotoxicity: a review of preclinical and clinical data	24
Novel therapies for AML: a round-up for clinicians	24
An update on drug development for the treatment of nonalcoholic fatty liver disease – from ongoing clinical trials to future therapy	23
UK Medical Cannabis registry: an analysis of clinical outcomes of medicinal cannabis therapy for chronic pain conditions	23
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	23
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	22

Update on diagnosis and treatment of immune thrombocytopenia	22
UK Medical Cannabis Registry: an analysis of clinical outcomes of medicinal cannabis therapy for generalized anxiety disorder	22
Pharmacological control of pain during propofol injection: a systematic review and meta-analysis	22
Safety and efficacy of therapies for chylomicronemia	22
Prevalence of polymorphisms in thiopurine metabolism and association with adverse outcomes: a South Asian region-specific systematic review and meta-analysis	21
Who is blind in psychedelic research? Letter to the editor regarding: blinding and expectancy confounds in psychedelic randomized controlled trials	21
Hippocampal volume, function, and related molecular activity in anorexia nervosa: A scoping review	20
Clinical pharmacology of antiplatelet drugs	20
The protective effect of tanshinone IIa on endothelial cells: a generalist among clinical therapeutics	19
Elagolix in the treatment of heavy menstrual bleeding associated with uterine fibroids in premenopausal women	19
Current status and prospects of IL-6–targeting therapy	18
Vaccination and their importance for lung transplant recipients in a COVID-19 world	18
SARS-CoV-2 protein drug targets landscape: a potential pharmacological insight view for the new drug development	18
Induction and maintenance of procedural sedation in adults: focus on remimazolam injection	18
Novel pharmacological therapies for the treatment of endometriosis	17
Opioid epidemic: lessons learned and updated recommendations for misuse involving prescription versus non-prescription opioids	17
The role of PCSK9 in NAFLD/NASH and therapeutic implications of PCSK9 inhibition	17
The value of deprescribing in older adults with dementia: a narrative review	16
Recent advances and future perspectives in the pharmacological treatment ofCandida aurisinfections	16
Detection of mobile colistin-resistance gene variants (mcr-1andmcr-2) in urinary tract pathogens in Bangladesh: the last resort of infectious disease management colistin efficacy is unde	16
Sex differences in COPD management	16
Drug delivery and targeting to brain tumors: considerations for crossing the blood-brain barrier	16
Finerenone: a mineralocorticoid receptor antagonist for the treatment of chronic kidney disease associated with type 2 diabetes	16
Opioids for chronic low back pain management: a Bayesian network meta-analysis	15
Selective FGFR/FGF pathway inhibitors: inhibition strategies, clinical activities, resistance mutations, and future directions	15
Recent advances in clearance monitoring of monoclonal antibodies in patients with inflammatory bowel diseases	15
Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials	15
The association between the use of sodium glucose cotransporter 2 inhibitor and the risk of diabetic retinopathy and other eye disorders: a systematic review and meta-analysis	14
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	14
Population pharmacokinetics of oxcarbazepine: a systematic review	14
Clinical trials with plants in diabetes mellitus therapy: a systematic review	14
WHO collaborative registration procedure using stringent regulatory authorities’ medicine evaluation: reliance in action?	14
Cannabidiol drug interaction considerations for prescribers and pharmacists	14
How do nocebo effects in placebo groups of randomized controlled trials provide a possible explicative framework for the COVID-19 pandemic?	13
Targeting the spectrum of immune checkpoints in prostate cancer	13
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life	13
Adverse events associated with nilotinib in chronic myeloid leukemia: mechanisms and management strategies	13
Efficacy and safety of injectable deoxycholic acid for submental fat reduction: a systematic review and meta-analysis of randomized controlled trials	13
The impact of body composition on treatment in ovarian cancer: a current insight	13
Peyronie’s disease: pharmacological treatments and limitations	13
Givosiran for the treatment of acute hepatic porphyria	13
Dostarlimab for the treatment of advanced endometrial cancer	13
Methotrexate and cardiovascular risk in rheumatic diseases:A comprehensive review	13
Cannabinoids and drug metabolizing enzymes: potential for drug-drug interactions and implications for drug safety and efficacy	12
Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	12
Prescription patterns of antiseizure drugs in tuberous sclerosis complex (TSC)-associated epilepsy: a multicenter cohort study from Germany and review of the literature	12
Treatment of infections in cancer patients: an update from the neutropenia, infection and myelosuppression study group of the Multinational Association for Supportive Care in Cancer (MASCC)	12
Perspectives on the pharmacological management of psoriasis in pediatric and adolescent patients	11
Patient initiation and maintenance of GLP-1 RAs for treatment of obesity	11
The effect of different contraceptive methods on the vaginal microbiome	11

Aminoadamantanes: from treatment of Parkinson’s and Alzheimer’s disease to symptom amelioration of long COVID-19 syndrome?	11
How to handle the delayed or missed dose of rivaroxaban in patients with non-valvular atrial fibrillation: model-informed remedial dosing	11
Clinical pharmacology of siRNA therapeutics: current status and future prospects	11
Quantitative efficacy of L-carnitine supplementation on glycemic control in type 2 diabetes mellitus patients	11
Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations	10
BNT162b2 mRNA COVID-19 vaccine is safe in a setting of patients on biologic therapy with inflammatory bowel diseases: a monocentric real-life study	10
Compounds of plants with activity against SARS-CoV-2 targets	10
Treatment challenges in adult female acne and future directions	10
Effects of metformin on body weight in polycystic ovary syndrome patients: model-based meta-analysis	10
Oral acetazolamide for intraocular pressure lowering: balancing efficacy and safety in ophthalmic practice	10
Efficacy and safety of liraglutide for obesity and people who are overweight: a systematic review and meta-analysis of randomized controlled trials	10
Metformin adverse event profile: a pharmacovigilance study based on the FDA Adverse Event Reporting System (FAERS) from 2004 to 2022	10
The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack	10
Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities	10
Assessing the potential for drug interactions and long term safety of melatonin for the treatment of insomnia in children with autism spectrum disorder	10
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	10
The new European guidelines for prevention of cardiovascular disease are misleading	10
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	10
Impact of red yeast rice supplementation on lipid profile: a systematic review and meta-analysis of randomized-controlled trials	9
Radical metastasectomy followed by sorafenib versus observation in patients withclear cell renal cell carcinoma: extended follow -up of efficacy results from the randomized phase II RESORT trial	9
Classes of drugs that target the cellular components of inflammation under clinical development for COPD	9
The effect of inhaled corticosteroids on the outcomes of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials	9
Pharmaceuticals agents for preventing NSAID-induced gastric ulcers: a patent review	9
Hematological toxicities associated with linezolid therapy in adults: key findings and clinical considerations	9
Clinical pharmacological innovation in the treatment of depression	9
Profiles of polypharmacy in older adults and medication associations with signs of aspiration	9
Growing role of SGLT2i in heart failure: evidence from clinical trials	9
Reliance: a smarter way of regulating medical products - The IPRP survey	8
Cenobamate tablets as a treatment for focal-onset seizures in adults	8
Effect of Perioperative Ketamine on Postoperative Mood and Depression: A Review of the Literature	8
Emapalumab for adult and pediatric patients with hemophagocytic lymphohistiocytosis	8
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	8
Sex and gender differences in the treatment of arterial hypertension	8
Pharmacological management of fibromyalgia: a Bayesian network meta-analysis	8
Lenvatinib: established and promising drug for the treatment of advanced hepatocellular carcinoma	8
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations	8
Reliance is key to effective access and oversight of medical products in case of public health emergencies	8
Treatment options following metformin in primary prevention populations with type 2 diabetes: which is the right road to take?	8
Clinical efficacy and safety of apatinib as maintenance treatment in patients with advanced esophageal squamous cell carcinoma	8
Nephroprotective effects of febuxostat and/or mirtazapine against gentamicin-induced nephrotoxicity through modulation of ERK 1/2, NF-κB and MCP1	8
Biologic and advanced immunomodulating therapeutic options for sarcoidosis: a clinical update	8
pre-existing diabetes and PTDM in kidney transplant recipients: how to handle immunosuppression	8
Real-world effectiveness of olanzapine and risperidone in the treatment of schizophrenia in Brazil over a 16-year follow-up period; findings and implications	8
Characteristics and clinical influence factors of arsenic species in plasma and their role of arsenic species as predictors for clinical efficacy in acute promyelocytic leukemia (APL) patients treated	8
Potential clinical applications of Ashwagandha (Withania somnifera) in medicine and neuropsychiatry	7
Treatment options for children with multi-drug resistant tuberculosis	7
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	7
Epoprostenol for the treatment of pulmonary arterial hypertension	7
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	7
Keeping up with venetoclax for leukemic malignancies: key findings, optimal regimens, and clinical considerations	7
Cannabidiol in low back pain: scientific rationale for clinical trials in low back pain	7
Clinical pharmacology of SGLT-2 inhibitors in heart failure	7
Favipiravir-based treatment for outcomes of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials	7
Do patients with immune-mediated thrombotic thrombocytopenic purpura receiving caplacizumab need antithrombotic therapy?	7
Bempedoic Acid: a cholesterol lowering agent with a novel mechanism of action	7
Sotagliflozin and decompensated heart failure: results of the SOLOIST-WHF trial	7
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder	7
Breaking down barriers for prescribing and using hormone therapy for the treatment of menopausal symptoms: an experts’ perspective	7
Fixed-dose combination of rosuvastatin and ezetimibe: treating hypercholesteremia according to cardiovascular risk	7
Ibuprofen and postoperative bleeding in children undergoing tonsillectomy or adenotonsillectomy: a systematic review and meta-analysis of randomized clinical trials.	7
Novel and emerging treatment strategies for lupus nephritis	7
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	7
Effect of laparoscopic sleeve gastrectomy on drug pharmacokinetics	6
Immune-related adverse events and immune checkpoint inhibitors: a focus on neurotoxicity and clinical management	6
Tumor mutational burden as a tissue-agnostic biomarker for cancer immunotherapy	6
Pharmacological profile of once-weekly injectable semaglutide for chronic weight management	6
Recent advances in the pharmacological management of sepsis-associated acute kidney injury	6
Population pharmacokinetics of omeprazole in obese and normal-weight adults	6
Advances in the pharmacological and regulatory management of multidrug resistant Helicobacter pylori	6
Insights into real-world treatment of cluster headache through a large Italian database: prevalence, prescription patterns, and costs	6
The changes of IgE levels in type 2 inflammatory diseases after treatment of dupilumab: a systematic review and meta-analysis	6
Clinical course of severe patients with COVID-19 treated with tocilizumab: report from a cohort study in Spain	6
Saliva for Model Informed Precision Dosing	6
Use of calcium channel blockers in dermatology: a narrative review	6
The impact of the COVID-19 pandemic lockdown measures on the prescribing trends and utilization of opioids in the English primary care setting: segmented-liner regression analysis	6
The paradigm of norgestimate: a third-generation testosterone-derivative progestin with a peripheral anti-androgenic activity and the lowest risk of venous thromboembolism	6
Obesity decreases the EC50 of epidural ropivacaine when combined with dexmedetomidine for labor analgesia	6
Incidence and risk of severe adverse events associated with trastuzumab emtansine (T-DM1) in the treatment of breast cancer: an up-to-date systematic review and meta-analysis of randomized controlled	6
Edoxaban for the treatment of pulmonary embolism in hospitalized COVID-19 patients	6
A model based on machine learning for the prediction of cyclosporin A trough concentration in Chinese allo-HSCT patients	6

Splicing deregulation, microRNA and notch aberrations: fighting the three-headed dog to overcome drug resistance in malignant mesothelioma	6
Comparing quality of life outcomes of JAK inhibitors and biological treatments for atopic dermatitis: a systematic review and network meta-analysis	6
Improving clozapine utilization will require continued advocacy, drug sponsor interest, and FDA support to address REMS issues	5
Peroxisome proliferator-activated receptor-gamma (PPARγ) and its immunomodulation function: current understanding and future therapeutic implications	5
Immunotherapy of High Risk Non-Muscle Invasive Bladder Cancer	5
A pharmacometric approach to evaluate drugs for potential repurposing as COVID-19 therapeutics	5
Effectiveness of polyene phosphatidylcholine and its combination with other drugs in patients with liver diseases based on real-world research	5
Update on drug interactions with non-vitamin-K-antagonist oral anticoagulants for stroke prevention in elderly patients	5
The effect of vitamin D supplementation on glycemic status of elderly people with prediabetes: a 12-month open-label, randomized-controlled study	5
Comparison of the relative efficacy of different biologics in different body areas in patients with moderate to severe psoriasis receiving biologics and tofacitinib in phase 3 randomized controlled tr	5
Proton pump inhibitors may reduce the risk of high-grade dysplasia and/or esophageal adenocarcinoma in Barrett’s esophagus: a systematic review and meta-analysis	5
Pharmacological and safety profile of a prolonged-release lanreotide formulation in acromegaly	5
Gender differences in new hypoglycemic drug effects on renal outcomes: a systematic review	5
Designer benzodiazepines: an update	5
Age and psoriatic arthritis are important predictors of biologic agent switch in psoriasis	5
Therapeutic approach to difficult-to-treat typical absences and related epilepsy syndromes	5
Commonly used immunosuppressive drugs for kidney diseases and pregnancy: focus on open questions	5
Intraperitoneal therapy for gastric cancer peritoneal carcinomatosis	5
Published population pharmacokinetic models of valproic acid in adult patients: a systematic review and external validation in a Chinese sample of inpatients with bipolar disorder	5
Tocilizumab for the treatment of non‐critical COVID‐19 pneumonia: an overview of the rationale and clinical evidence to date	5
A novel long-acting local anesthetic – HTX-011 (ZYNRELEF™) for postoperative pain control	5
Encouraging appropriate use of proton pump inhibitors: existing initiatives and proposals for the future	5
Time to incorporate preemptive NUDT15 testing before starting thiopurines in inflammatory bowel disease in Asia and beyond: a review	5
Non-vitamin K antagonist oral anticoagulants for stroke prevention in atrial fibrillation: safety issues in the elderly	5
The role of the alternative pathway in paroxysmal nocturnal hemoglobinuria and emerging treatments	5
Effects of anti-diabetic treatments in type 2 diabetes and fatty liver disease	5
Telmisartan/hydrochlorothiazide-induced nevus-associated cutaneous melanoma: first report in the medical literature	5
A review of recent advances in the treatment of adults with complicated urinary tract infection	5
Understanding the role of chronopharmacology for drug optimization: what do we know?	4
Abiraterone acetate versus docetaxel for metastatic castration-resistant prostate cancer: a cohort study within the French nationwide claims database	4
Combination immunotherapy strategies for triple-negative breast cancer: current progress and barriers within the pharmacological landscape	4
Epoetin alfa-epbx: a new entrant into a crowded market. a historical review of the role of erythropoietin stimulating agents and the development of the first epoetin biosimilar in the United States	4
Interactions of antiepileptic drugs with drugs approved for the treatment of indications other than epilepsy	4
Evinacumab for the treatment of homozygous familial hypercholesterolemia	4
Updates in the diagnosis and practical management of allergic rhinitis	4
Parametric population pharmacokinetics of isoniazid: a systematic review	4
Exploring the room for repurposed hydroxychloroquine to impede COVID-19: toxicities and multipronged combination approaches with pharmaceutical insights	4
Potential approaches using teneligliptin for the treatment of type 2 diabetes mellitus: current status and future prospects	4
Evogliptin for the treatment option for type 2 diabetes: an update of the literature	4
Clinical pharmacology of cardiac cyclic AMP in human heart failure: too much or too little?	4
Developing a latent class analysis model to identify at-risk populations among people using medicine without prescription	4
Risk of bleeding associated with BTK inhibitor monotherapy: a systematic review and meta-analysis of randomized controlled trials	4
Melflufen for the treatment of multiple myeloma	4
Pharmacological and clinical profile of cefiderocol, a siderophore cephalosporin against gram-negative pathogens	4
Pharmacological strategies for the management of the antisocial personality disorder	4
Biologics and small molecules in the management of psoriatic arthritis: Reproduction related issues in female and male patients	4
Why is diagnosis, investigation, and improved management of kidney stone disease important? Non-pharmacological and pharmacological treatments for nephrolithiasis	4
Oral drugs used to treat persistent pulmonary hypertension of the newborn	4
Bridging the gap in cardiovascular care in diabetic patients: are cardioprotective antihyperglycemic agents underutilized?	4
TYK2 as a novel therapeutic target in psoriasis	4
Comparison of the registration process of the medicines control authority of Zimbabwe with Australia, Canada, Singapore, and Switzerland: benchmarking best practices	4
Real-world clinical effectiveness of once-weekly semaglutide in patients with type 2 diabetes: a systematic literature review	4
Artificial intelligence and machine learning in clinical pharmacological research	4
BMI but not age and sex negatively impact on the outcome of pharmacotherapy in fibromyalgia: a systematic review	4
The coincidence of increased risk of atrial fibrillation in randomized control trials of omega-3 fatty acids: a meta-analysis	4
Safety assessment of propranolol for infantile hemangioma: a study in an Asian population	4
The efficacy of vitamin D in treatment of fibromyalgia: a meta-analysis of randomized controlled studies and systematic review	4
Therapeutic approach to neurological manifestations of Angelman syndrome	3
Clozapine for treatment refractory catatonia in individuals with autism spectrum disorder: a retrospective chart review study	3
Sodium zirconium cyclosilicate for the management of chronic hyperkalemia in kidney disease, a novel agent	3
A pharmacological overview of aprepitant for the prevention of postoperative nausea and vomiting	3
Stimulant and hallucinogenic novel psychoactive substances; an update	3
Efficacy and safety of compound glycyrrhizin in the patients with vitiligo: a systematic review and meta-analysis	3
131-I-metaiodobenzylguanidine and chemotherapy for advanced neuroblastoma	3
Influence of N -acetyltransferase 2 polymorphisms and clinical variables on liver function profile of tuberculosis patients	3
Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants	3
Predicting plasma concentration of quetiapine in patients with depression using machine learning techniques based on real-world evidence	3
Clinical pharmacology of emicizumab for the treatment of hemophilia A	3
Genetic markers of drug hypersensitivity in pediatrics: current state and promise	3
Clostridioides difficile resistance to antibiotics, including post-COVID-19 data	3
The era of lenalidomide maintenance therapy in multiple myeloma: settings for achieving best outcomes	3
Identifying and categorizing compounds that reduce corneal transforming growth factor beta induced protein levels: a scoping review	3
Managing blood disorders during the Covid-19 pandemic: current pharmacological insights	3
Effect of renal impairment on arsenic accumulation, methylation capacity, and safety in acute promyelocytic leukemia (APL) patients treated with arsenic trioxide	3
Getting immunosuppression just right: the role of clinical biomarkers in predicting patient response post solid organ transplantation	3
How to treat histone 3 altered gliomas: molecular landscape and therapeutic developments	3
Extending the ambit of SGLT2 inhibitors beyond diabetes: a review of clinical and preclinical studies on non-diabetic kidney disease	3
The expert clinical pharmacological advice program for tailoring on real-time antimicrobial therapies with emerging TDM candidates in special populations: how the ugly duckling turned into a swan	3
Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study	3
A comprehensive strategy to address shortage of Erwinia asparaginase in pediatric acute lymphoblastic leukemia	3
Early-life exposure to antibiotics and subsequent development of atopic dermatitis	3
Comparing immunotherapies to other frequently used treatments of gastric cancer	3
Concomitant use of dexamethasone and tetracyclines: a potential therapeutic option for the management of severe COVID-19 infection?	3
Telmisartan (and/or nitrosamine) - induced occult melanoma: first reported case in world literature	3
The nocebo phenomenon in the COVID-19 pandemic: a nocebodemic effect	3
Critical appraisal of evidence for anti-Xa monitoring and dosing of low-molecular-weight heparin in renal insufficiency	3
Difelikefalin for the treatment of moderate-to-severe pruritus associated with chronic kidney disease on hemodialysis	3
Pediatric attention deficit hyperactivity disorder (ADHD): 2022 updates on pharmacological management	3
Factors affecting the efficacy and safety of docetaxel combined with platinum in the treatment of advanced non-small cell lung cancer	3
A review of alternative intravenous acetylcysteine regimens for acetaminophen overdose	3
A systematic review and meta-analysis of the effect of statin treatment on sVCAM-1 and sICAM-1	3
Hugan tablets for the treatment of RUCAM based drug-induced liver injury: a propensity score matching analysis using a nationwide database	3
A profile of delafloxacin in the treatment of adults with community-acquired bacterial pneumonia	3
Antiplatelet therapy after noncardioembolic ischemic stroke or transient ischemic attack	3
Past, present, and future of FGFR inhibitors in cholangiocarcinoma: from biological mechanisms to clinical applications	3