Expert Review of Clinical Pharmacology

Article	Citations
Personalizing tamoxifen therapy in adjuvant therapy: a brief summary of the ongoing discussion	55
Effects of the augmentation with quetiapine or olanzapine on the metabolism of duloxetine: a retrospective analysis	53
A review of current and emerging therapies in breast cancer: implications for older adults	50
Renin angiotensin aldosterone inhibitors in the treatment of proteinuria in children with congenital anomalies of the kidney and urinary tract: more evidence needed	40
Prostate cancer and novel pharmacological treatment options–what’s new for 2022?	39
Clinical pharmacology of antiplatelet drugs	37
Therapeutic drug monitoring of antiretroviral therapy: current progresses and future directions	35
Reducing the risk of death – a possible outcome in COPD patients	34
Sparsentan: a dual endothelin and angiotensin II receptor antagonist approved for IgA nephropathy	34
Strategies for lowering lipoprotein(a): a spotlight on novel pharmacological treatments	33
A simulation study to assess the influence of population pharmacokinetic model selection on Bayesian forecasting of vancomycin exposure in preterm neonates	32
Risk of new onset diabetes mellitus with pitavastatin as compared to atorvastatin and rosuvastatin: a systematic review and meta-analysis	31
Pharmacological and clinical profile of ravulizumab 100 mg/mL formulation for paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome	28
What is the potential for abuse of lisdexamfetamine in adults? A preclinical and clinical literature review and expert opinion	28
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	27
Sodium-glucose cotransporter 2 inhibitors in frail, older people with type 2 diabetes and heart failure: do we have enough evidence to confidently support the use?	27
Practical considerations and emerging approaches for the management of vasomotor and sexual symptoms in breast cancer patients on endocrine therapies	25
Cannabidiol drug interaction considerations for prescribers and pharmacists	22
Medical management of pediatric chronic rhinosinusitis	22
Role of tenecteplase in ischemic stroke after 4.5 hours: an evaluation of the TRACE-III trial	22
Amylin analogs for the treatment of obesity without diabetes: present and future	22
Management of polypharmacy through deprescribing in older patients: a review of the role of AI tools	22
Broadening access to tenofovir alafenamide for the treatment and prevention of HIV-1 infection	21
Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy	21
Treatment management for rosacea: current pharmacological and non-pharmacological options	20

Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials	20
Reply to: The risk for genito-urinary infections with sodium-glucose cotransporter-2 inhibitors: duration rather than dose matter?	20
Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective	18
Nirmatrelvir/Ritonavir and molnupiravir: an update on COVID-19 antivirals in the Omicron era	18
Complications related to oral corticosteroid use in asthma patients: a retrospective cohort study	18
OPTIMA-ID: development and validation of a medicine optimization tool for older adults with intellectual disability	17
Intestinal microbiome and epilepsy: a new therapeutic approach?	17
The thiazide-like diuretic chlorthalidone as an alternative evidence-based therapy for resistant hypertension in patients with stage 4 chronic kidney disease	17
CYP2C19 genotype-guided dosing of proton pump inhibitors: progress in clinical trials and real-world use	16
Clinical pharmacology of SGLT-2 inhibitors in heart failure	16
Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis	16
Reconsidering molecular pathways in giant benign prostatic hyperplasia: a potential strategy for an unmet challenge	16
Association between sodium-glucose cotransporter 2 inhibitors and eye disorders: a systematic review and meta-analysis	16
Pharmacological strategies for the management of the antisocial personality disorder	16
Drug-drug interactions associated with FLT3 inhibitors for acute myeloblastic leukemia: current landscape	16
Population pharmacokinetic modeling and exposure-response analysis of anrikefon: insights and implications in clinical analgesia	15
Recent advances and unmet needs in the treatment of drug-resistant tuberculosis	15
Current status and prospects of IL-6–targeting therapy	15
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic review and meta-analysis	14
FLOT vs CROSS in localized esophageal adenocarcinoma: what is the current best strategy?	14
Clozapine for older adults with severe mental illness: a systematic review and expert recommendations for clinical practice	14
Population pharmacokinetic modeling of piperacillin in critically ill adult patients: consideration of sex-based differences during model development	14
A narrative review of non-racemic amisulpride (SEP-4199) for treatment of depressive symptoms in bipolar disorder and LB-102 for treatment of schizophrenia	14
Pediatric attention deficit hyperactivity disorder (ADHD): 2022 updates on pharmacological management	14
Antimicrobial safety considerations in critically ill patients: part II: focused on anti-microbial toxicities	14
Hydroxyurea in the sickle cell disease modern era	14
A profile of azetukalner for the treatment of epilepsy: from pharmacology to potential for therapy	14
Osteoarthritis and cardiometabolic diseases: shared mechanisms, modifiable risk factors, and integrated management strategies	13
Emerging pharmacological options in the treatment of idiopathic pulmonary fibrosis (IPF)	13
Real-world clinical effectiveness of once-weekly semaglutide in patients with type 2 diabetes: a systematic literature review	13
Methotrexate polyglutamates	13
Methenamine Hippurate in UTI management: a reemerging pharmacological strategy	13
Innovation in pediatric atopic dermatitis care: examining emerging topical treatment options	13
Current and emerging pharmacotherapies for treating vascular malformations	13
Shaping future deprescribing priorities: outcomes of a World Café stakeholder workshop	13
Progress in the pharmacological management of vasovagal syncope	12
Phosphatidylinositol 3 kinase inhibitor-related pneumonitis: a systematic review and meta-analysis	12
Physiologically-based pharmacokinetic modeling to predict the exposure and provide dosage regimens of adalimumab in patients with juvenile idiopathic arthritis	12
Pharmacogenomics – a minor rather than major force in clinical medicine	12
The nocebo phenomenon in the COVID-19 pandemic: a nocebodemic effect	12
Efficacy and safety of tislelizumab for malignant solid tumor: a systematic review and meta-analysis of phase III randomized trials	12
Risk factors for a broken heart: understanding drug-induced causes for Takotsubo syndrome and pharmacological treatment options	12
A systematic review and meta-analysis of users versus non-users: unveiling the influence of proton pump inhibitors on capecitabine efficacy in colorectal cancer	11
Pharmacokinetic interaction of quetiapine and lamotrigine – victim and perpetrator?	11
Early response is a strong predictor of the long-term response in psoriasis patients receiving risankizumab or guselkumab in the real-world: a retrospective analysis	11
Designer benzodiazepines: an update	11
Pharmacotherapy for previously treated gastric cancer patients: current options and future developments	11
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	11
Optimization of secukinumab dose regimens in patients with moderate-to-severe plaque psoriasis via exposure-response modeling	11
Efficacy and safety of dupilumab in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis	10

TYK2 as a novel therapeutic target in psoriasis	10
Signal mining study of severe cutaneous adverse events of valaciclovir or acyclovir based on the FAERS database	10
Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	10
Encouraging appropriate use of proton pump inhibitors: existing initiatives and proposals for the future	10
PREG-ADR: development and validation of a predictive tool for adverse drug reactions in hospitalized pregnant women	10
Is therapeutic drug monitoring a dancing partner for TNF-α inhibitors in real-world practice? Answers from an updated systematic review and meta-analysis	10
Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight	10
Clinical pharmacology of siRNA therapeutics: current status and future prospects	10
Genito-urinary infectious adverse events related to sodium glucose cotransporter-2 inhibitors: a network meta-analysis and meta-regression	10
Golimumab retention in patients with psoriatic arthritis and axial spondyloarthritis: evidence from up to a decade of follow-up	10
Comparison of dopamine D2 receptor occupancy profiles between risperidone ISM versus oral risperidone and monthly paliperidone palmitate based on population pharmacokinetic modelling and simulations	10
Revolutionizing diabetes care: unveiling tirzepatide’s potential in glycemic control and beyond	10
Hormonal contraception, past, present, and future part 1: the early path – facts, stories, and controversies	9
Pharmacological treatment for transforming growth factor beta induced corneal dystrophies: what is the way forward?	9
Practical challenges and considerations in adopting biosimilars in oncology clinical practice within a large healthcare system	9
Dasiglucagon for treating severe hypoglycemia in patients with diabetes	9
The future of pharmacology education: The Veterinary Educators in Pharmacology Special Interest Group (VEPSIG)	9
The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock	9
Advances in pharmacokinetic-pharmacodynamic modelling for pediatric drug development: extrapolations and exposure-response analyses	9
Psychedelic drugs for the treatment of substance use disorders	9
Antimicrobial safety considerations in critically ill patients: part I: focused on acute kidney injury	9
The orexin system and alcohol use disorder: bridging the gap between preclinical and clinical research	9
Statin-related neurocognitive disorder: a real-world pharmacovigilance study based on the FDA adverse event reporting system	9
Optimizing outcomes and managing adverse events in locally advanced or metastatic urothelial cancer: a clinical pharmacology perspective	8
Considerations when prescribing opioid agonist therapies for people living with HIV	8
Intravitreal immunotherapy in non-infectious uveitis: an update	8
Current understanding of the etiology of cyclic vomiting syndrome and therapeutic strategies in its management	8
Availability and evaluation of medication management resources for carers of people with dementia: a scoping review with an environmental scan	8
Reliance is key to effective access and oversight of medical products in case of public health emergencies	8
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective, and interventions to suppor	8
Detrimental impact of gastric acid suppressants on vascular endothelial growth factor receptor tyrosine kinase inhibitors efficacy: evidence from a systematic review and meta-analysis	8
Pharmacology considerations for managing pregnancy in women with systemic lupus erythematosus	8
Clozapine for treatment refractory catatonia in individuals with autism spectrum disorder: a retrospective chart review study	8
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	8
Novel and emerging treatment strategies for lupus nephritis	8
Genotype-guided pharmacotherapy: the challenges of integrating pharmacogenomic testing into routine healthcare with a focus on experiences at a single site	8
Clinical outcomes of oral anticoagulant discontinuation in atrial fibrillation: a systematic review and meta-analysis	8
Adverse clinical outcomes associated with drug-related hospitalizations in people with dementia	8
Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia	8
GLP-1 receptor agonist safety in a perioperative setting: more questions than answers	7
Implementing pharmacogenetics in clinical trials: considerations about current methodological, ethical, and regulatory challenges	7
Efficacy and safety of statins for nonalcoholic/metabolic dysfunction-associated fatty liver diseases: a systematic review and meta-analysis	7
Emerging pharmacological strategies for treating and preventing mpox	7
The need for inhaled phosphodiesterase inhibitors in chronic obstructive pulmonary disease	7
The outcomes of considering goals of care in medication reviews for older adults: a systematic review	7
Vaping Δ 9 -tetrahydrocannabinol (Δ 9 -THC) in liquid forms: pharmacokinetics, pharmacodynamics, a	7
Next-generation sequencing in pharmacogenomics – fit for clinical decision support?	7
The changes of IgE levels in type 2 inflammatory diseases after treatment of dupilumab: a systematic review and meta-analysis	7
A tiered decisional framework for genetic epileptic syndromes with or without encephalopathies: from standard care to investigational strategies	7
Closing the gaps in the access to quality-assured medicines for global health: The case for oxytocin for postpartum haemorrhage	7
The ketamine chameleon: history, pharmacology, and the contested value of experience	7
The role of glucagon-like peptide-1 receptor agonists in nonalcoholic fatty liver disease	7
Treatment and prevention of influenza in geriatric patients	7
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective	7
Impact of SGLT2 inhibitors on the kidney in people with type 2 diabetes and severely increased albuminuria	7
Quantitative effects of sodium-glucose cotransporter-2 inhibitors on liver functions in patients with nonalcoholic fatty liver disease	7
An overview on disease modifying and symptomatic drug treatments for multiple sclerosis	7
Factor-VIII mimetic bispecific antibodies for the treatment of hemophilia A: an update	7
3D printing – an alternative strategy for pediatric medicines	6
Drug–drug interactions in targeted cancer therapies: a focus on tyrosine kinase inhibitors	6
Challenges, unmet needs and future directions – a critical evaluation of the clinical trial landscape in schizophrenia research	6
Traumatic brain injury. Rethinking pharmacological clinical trials in an orphan pathology	6
Sex and gender differences in the treatment of arterial hypertension	6
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder	6
Ribosomopathies and cancer: pharmacological implications	6
Optimization of potassium management in patients with chronic kidney disease and type 2 diabetes on finerenone	6
Therapeutic drug monitoring for de-escalating anti-tumor necrosis factor therapy in patients with inflammatory bowel disease	6
Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities	6
Correction	6
Centering the patient in decisions about opioid tapering	6
Vestibular function in children with generalized epilepsy and treated with valproate	6
Pharmacokinetics, efficacy, and safety of arsenic formulations in acute promyelocytic leukemia treatment	6
A model based on machine learning for the prediction of cyclosporin A trough concentration in Chinese allo-HSCT patients	6
Novel pharmacological therapies for the treatment of endometriosis	6
Therapeutic approach to neurological manifestations of Angelman syndrome	6
Correction	6
The evolution of clinical trials for pediatric pulmonary hypertension: are the needs of patients and their caregivers being met?	6
Bridging the gap in cardiovascular care in diabetic patients: are cardioprotective antihyperglycemic agents underutilized?	6
The effect of different levothyroxine administration regimens on thyroid hormone levels: a systematic review, pairwise, and network meta-analysis	5
Scoping review of the availability and uptake of disease modifying therapies in children and adolescents with multiple sclerosis	5

Perspectives on deprescribing in palliative care	5
Efficacy and safety of insulin detemir versus glargine in patients with diabetes: a systematic review and meta-analysis	5
A comprehensive systematic review of the types of medication classes targeted by deprescribing tools and the tools/interventions applied to each class	5
A comprehensive strategy to address shortage of Erwinia asparaginase in pediatric acute lymphoblastic leukemia	5
Psychiatric and non-psychiatric drugs causing false-positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS	5
Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension	5
Comparison of the relative efficacy of different biologics in different body areas in patients with moderate to severe psoriasis receiving biologics and tofacitinib in phase 3 randomized controlled tr	5
Clostridioides difficile resistance to antibiotics, including post-COVID-19 data	5
The effect of inhaled corticosteroids on the outcomes of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials	5
Integrating homologous recombination deficiency and replication stress: converging strategies unlocking new frontiers in precision oncology	5
Biosimilar and generic formulations of novel antidiabetic drugs: the role of liraglutide in clinical pharmacology of type 2 diabetes	5
Semaglutide for the treatment of MASH: reaching into the ESSENCE of cardio-metabolic health?	5
Optimizing ganciclovir and valganciclovir dosing regimens in pediatric patients with cytomegalovirus infection: a spotlight on therapeutic drug monitoring	5
STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: uptake and clinical impact	5
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	5
A profile of delafloxacin in the treatment of adults with community-acquired bacterial pneumonia	5
Optimizing anticholinergic use in urology: strategies for safe prescribing amidst polypharmacy	5
Prescribing pattern of disease-modifying antirheumatic drugs in Scotland (2019–2023): a population-based retrospective cohort study	5
Hormonal contraception, past, present, and future part 2: optimizing combined oral contraceptives to decrease risks for healthy women	5
Chelating anticoagulants reduce plasma doxycycline measurements: implications for doxy PEP monitoring	5
Pharmacological approaches to prevent vertical transmission of HIV and HBV	5
Influence of N -acetyltransferase 2 polymorphisms and clinical variables on liver function profile of tuberculosis patients	5
Renin–angiotensin system inhibition and mortality in patients undergoing dialysis with coronary artery disease: insights from a multi-center observational study	5
Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes	5
Snakebite-associated thrombotic microangiopathy: a spotlight on pharmaceutical interventions	5
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations	5
Correction	5
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	5
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials	5
The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack	5
Steady-state pharmacokinetics, efficacy, and safety of bictegravir in Chinese patients with HIV: an observational study	5
Artificial intelligence and machine learning in clinical pharmacological research	4
Updates in the diagnosis and practical management of allergic rhinitis	4
Correction	4
The evolving landscape of PARP inhibitors in castration-resistant prostate cancer: a spotlight on treatment combinations	4
Current status of biological therapy use for older adults with severe asthma	4
Artificial intelligence-based model for dose prediction of sertraline in adolescents: a real-world study	4
Type of proteinuria might be essential for RAAS-I treatment in children with CAKUT	4
Therapeutic drug monitoring-guided dosing for pediatric cystic fibrosis patients: recent advances and future outlooks	4
Stimulant and hallucinogenic novel psychoactive substances; an update	4
A scoping review of the clinical utility of adverse drug reaction causality analysis tools for use in the hospital setting	4
Considerations for the treatment of older adults with chronic lymphocytic leukemia	4
Impact of COVID-19 pandemic on the prescribing pattern of oral anticoagulants in the English primary care setting: a population-based segmented interrupted time series analysis of over 53 million indi	4
Comparative effectiveness and safety of inhaled corticosteroid plus long-acting β 2 -agonist fixed-dose combinations vs. long-acting muscarinic antag	4
Pharmacovigilance in the field of addiction: challenges and emerging solutions	4
PD-1/PD-L1 for prostate cancer: from clinical trials to practice	4
The search for blood biomarkers useful in treating atopic dermatitis patients	4
The efficacy and toxicity of mirvetuximab soravtansine, a novel antibody-drug conjugate, in the treatment of advanced or recurrent ovarian cancer: a meta-analysis	4
The association between the use of sodium glucose cotransporter 2 inhibitor and the risk of diabetic retinopathy and other eye disorders: a systematic review and meta-analysis	4
Novel insights into molecular and cellular aspects of delayed drug hypersensitivity reactions	4
The effect of epilepsy and antiseizure medications on cardiac autonomic functions in children with epilepsy	4
Therapeutic effects of topical cetirizine in the treatment of female pattern hair loss: a randomized controlled noninferiority trial	4
Analyzing the clinical efficacy and safety of levocetirizine based on its receptor occupancy, intraclass comparison and role in the treatment of CSU: an AROG consensus statement	3
Drug related adverse event assessment in neonates in clinical trials and clinical care	3
Evogliptin for the treatment option for type 2 diabetes: an update of the literature	3
Sodium-glucose co-transporter 2 inhibition and acute myocardial infarction: the DAPA-MI and EMPACT-MI trials	3
The outcomes of goal-oriented medication reviews for the elderly: current research and future directions	3
Updates in innovation of the treatment of pyoderma gangrenosum	3
Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study	3
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	3
Samidorphan for the treatment of weight gain associated with olanzapine in patients with schizophrenia and bipolar disorder	3
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	3
Pharmacological interventions for alcohol use disorder: novel insights from recent clinical trials	3
Impact of gabapentinoids’ reclassification policy and COVID-19 on gabapentinoids’ utilization pattern and their associated mortality in Scotland and Northern Ireland: a segmental regression analysis	3
Rethinking anticholinergic burden in older adults: innovative approaches to detection and management	3
Set and setting predict psychopathology, wellbeing and meaningfulness of psychedelic experiences: a correlational study	3
Therapeutic drug monitoring of Janus kinase inhibitors for precision dosing: where do we stand ?	3
AI-enhanced therapeutic drug monitoring for vancomycin and β-lactam antibiotics in critical care: from population PK to bedside algorithms	3
Response to letter to the editor: therapeutic importance of proteinuria classification in children with congenital anomalies of the kidney and urinary tract	3
A review of recent advances in the treatment of adults with complicated urinary tract infection	3
An update on the treatment paradigm for non-clear cell renal cell carcinoma	3
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	3
Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers	3
Pharmacological management of testosterone deficiency in men current advances and future directions	3
Dual incretin agonism and the gut microbiome: does the heart of metabolic regulation beat in the gut?	3
Potential approaches using teneligliptin for the treatment of type 2 diabetes mellitus: current status and future prospects	3
Efficacy and safety of oliceridine treatment in patients with postoperative pain: a systematic review and meta-analysis of randomized controlled trials	3
Finerenone: a mineralocorticoid receptor antagonist for the treatment of chronic kidney disease associated with type 2 diabetes	3
A profile of safety and efficacy of fezolinetant for the treatment of menopausal vasomotor symptoms	3
Clinical considerations when switching antiretroviral therapy	3
JAK inhibitors in vitiligo: what they hit and what they miss - an immunopathogenesis based exposition of existing evidence	3
A scoping review of legibility of hand-written prescriptions and drug-orders: the writing on the wall	3
Gene therapy in cardiology: pioneering a new era in medical ethics and patient care	3
Regional variation in longitudinal trajectories of primary care opioids prescribing across Health Boards in Scotland: a population-based study	3
COMBINE 2 is better than one: shaping the future of therapeutics in inadequately controlled type 2 diabetes	3
Semaglutide and smoking cessation in individuals with type 2 diabetes mellitus: there is no smoke without fire!	3
Letermovir and new horizons in prevention of post-transplant CMV	3