OOIR: Observatory of International Research

Papers

(The TQCC of Immunotherapy is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Identifying risk factors and biomarkers for severe CIP in lung cancer patients– a retrospective case series study	81
Atezolizumab and Bevacizumab prior to liver transplantation in hepatic angiosarcoma mimicking hepatocellular carcinoma	67
Real-world Study of Hepatic Artery Infusion Chemotherapy Combined With Anti-PD-1 Immunotherapy and Tyrosine Kinase Inhibitors for Advanced Hepatocellular Carcinoma	57
Cost–Effectiveness Analysis of Serplulimab as First-Line Treatment for Advanced Esophageal Squamous Cell Carcinoma	46
An Update on the Adalimumab Biosimilar Landscape Following Approval of the First High-Concentration Biosimilar	36
Imaging of brain metastases treated with immune checkpoint inhibitors	32
Pembrolizumab Plus Chemotherapy for Advanced Non-Small-Cell Lung Cancer Without Tumor Pd-L1 Expression in Asia	31
Real-World Outcomes with Immuno-Oncology Therapies in Advanced Melanoma: Final Results of the OPTIMIzE Registry Study	28
Alemtuzumab-Induced Red Cell Aplasia And Other Immune Cytopenias: Not So Â€˜Pureâ€™	27
Pembrolizumab in patients from China with microsatellite instability-high/mismatch repair deficient tumors: KEYNOTE-158	25
Uric acid level in metastatic renal cell carcinoma treated with nivolumab: a Turkish Oncology Group Kidney Cancer Consortium (TKCC) study	25
Postvaccination immune-mediated hepatitis: what do we really know?	21
Safety and Effectiveness of the 300 IR Sublingual House Dust Mite Allergen Immunotherapy Tablet: 2-Year Interim Analysis of a Specified Drug-Use Survey	20
Targeting PD-1/PD-L1 in Biliary Tract Cancer: Role and Available Data	17
Subcutaneous Immunoglobulin Use in Immunoglobulin-Naive Patients with Primary Immunodeficiency: A Systematic Review	16
Therapeutic lymph node dissection with neoadjuvant immunotherapy for macroscopic melanoma – too much skin in the game?	16
Treatment and Overall Survival Among Anti-PD-1-Exposed Advanced Melanoma Patients with Evidence of Disease Progression	15
Pd-1, Pd-L1, Ido, Cd70 and Microsatellite Instability as Potential Targets to Prevent Immune Evasion in Sarcomas	15
Low-Dose Metronomic Gemcitabine Pretreatments Overcome the Resistance of Breast Cancer to Immune Checkpoint Therapy	14
Immunotherapy for Gastric Cancer: A 2021 Update	14
Anlotinib Succeeded in Rescue Therapy For Hyperprogression Induced by Immune Checkpoint Inhibitors: A Case Report	13
Secukinumab in the treatment of psoriatic arthritis or ankylosing spondyloarthritis with multiple sclerosis: a case series with literature review	13
Assessing Pd-L1 Status in Mrcc Treated with First-Line Immune-Based Combinations: A Meta-Analysis	13
Real-world data of immune-related adverse events in lung cancer patients receiving immune-checkpoint inhibitors	13
Uveitis Associated with Cancer Immunotherapy: Long-Term Outcomes	13

What is the future of immune checkpoints inhibitors for metastatic triple negative breast cancers?	13
Safety and Efficacy of Mutant Neoantigen-Specific T-Cell Treatment Combined Anti-Pd-1 Therapy in Stage Iv Solid Tumors	13
A phase 1 study of the CD40 agonist MEDI5083 in combination with durvalumab in patients with advanced solid tumors	13
Cancer Immunotherapy Via Stem Cell-Derived NK Cells	12
Nivolumab induced discolouration of the tongue: a case report	12
Durvalumab after Chemoradiotherapy in Patients with Stage III Non-Small-Cell Lung Cancer: Real-World Outcomes Versus Clinical Trial Results	12
Adherence, persistence and treatment switching in psoriasis	12
Prognostic Value of Soluble Programmed Cell Death Ligand-1 in Patients with Non-Small-Cell Lung Cancer: A Meta-Analysis	12
4-1BB Antibody Enhances Cytotoxic Activity of Natural Killer Cells Against Prostate Cancer Cells Via NKG2D Agonist Combined with IL-27	12
Cost–Effectiveness of Pembrolizumab Plus Chemotherapy as First-Line Treatment in PD-L1-Positive Metastatic Triple-Negative Breast Cancer	12
Lessons From the Diagnosis and Treatment of Severe Immune Checkpoint Inhibitor-Associated Pneumonia: A Case Report	11
Efficacy of mIte Allergen Immunotherapy in Allergic Rhinitis and the Immune Synergistic Effect on Cross-Allergens	11
Sintilimab-induced severe erosive hemorrhagic gastritis and pyloric obstruction: a case report and literature review	11
Current Immunosuppression Strategies in Pediatric Heart Transplant	11
Molecular Interactions of Antibodies with PD-1/PD-L1 Proteins	11
Effectiveness of allergen immunotherapy with house dust mite extract for pediatric bronchial asthma	11
Dendritic Cell-Based Immunotherapy: A Potential Player in Oral Cancer Therapeutics	10
Liquid biopsy for guiding breast cancer immunotherapy	10
Immune-Checkpoint Inhibitors in Renal Transplanted Patients Affected by Melanoma: A Systematic Review	10
Integrase inhibitors: current protagonists in antiretroviral therapy	10
SAFFRON-103: A Phase Ib Study of Sitravatinib Plus Tislelizumab in Anti-PD-(L)1 Refractory/Resistant Advanced Melanoma	10
Deucravacitinib in Moderate-To-Severe Psoriasis	10
Gastrointestinal toxicities associated with immune checkpoint inhibitors therapy: risks and management	10
Immune Checkpoint Inhibitors in Cholangiocarcinoma	10
Infection Rates and Tolerability of Three Different Immunoglobulin Administration Modalities in Patients with Primary Immunodeficiency Diseases	10
Durvalumab in Advanced Cholangiocarcinoma: Is Someone Knocking Down the Door?	10
Emerging Advances in Nanomedicine for Breast Cancer Immunotherapy: Opportunities and Challenges	10
Poor Response to Sintilimab Plus Chemotherapy in a Pulmonary Epithelioid Hemangioendothelioma Patient: A Case Report	10
Applications and Current Challenges of Chimeric Antigen Receptor T Cells in Treating High-Grade Gliomas in Adult and Pediatric Populations	10
Antithymocyte Globulin for Aplastic Anemia Secondary to Pembrolizumab: A Case Report and Review of Literature	9
Immune Checkpoint Inhibitor-Induced Autoimmune Encephalitis in Metastatic Squamous Cell Lung Cancer	9
Human Growth Hormone Supplement Promotes Human Lymphohematopoietic Cell Reconstitution in Immunodeficient Mice	9
Effectiveness of COVID-19 Vaccines Against Omicron Variant	9
Immune-Related Gigantomastia: A Case Study	9
A Summertime Pause in Immunoglobulin Replacement Therapy: A Prospective Real-World Analysis	9
Treatment of Plaque Psoriasis with Deucravacitinib (POETYK PSO-1 Study): A Plain Language Summary	9
Indirect Comparison of Pembrolizumab Monotherapy Versus Nivolumab + Ipilimumab in First-Line Metastatic Lung Cancer	8
Late-Onset Toxicities of Monoclonal Antibodies in Cancer Patients	8
Autophagy in combination therapy of temozolomide and IFN-γ in C6-induced glioblastoma: role of non-coding RNAs	8
A Meta-Analysis of Application of Pd-1/Pd-L1 Inhibitor-Based Immunotherapy in Unresectable Locally Advanced Triple-Negative Breast Cancer	8
Ipilimumab and Nivolumab: The ‘New Kid on the Block’ in Advanced Angiosarcoma	8
Steroid-Dependent Polyarthritis Induced by Immune Checkpoint Inhibitor Therapy Successfully Treated with Bimekizumab	8
Immune Checkpoint Inhibitors in Lung Tumors with Rare Histologies and Other Thoracic Malignancies	8
Peripheral blood cytokines and outcomes with immune checkpoint blockade: a systematic review and meta-analysis	8
TOPAZ-1: A New Standard of Care for Advanced Biliary Tract Cancers?	8
Breaking the mold: nontraditional approaches to allergen immunotherapy for environmental allergens	8
Therapeutic Intervention of Glioma with the Novel Antineoplastic Agent T11TS: The Story so Far	8
Infectious Adverse Events in Patients with Atopic Dermatitis Treated with Baricitinib	8
Mepolizumab in Chronic Rhinosinusitis with Nasal Polyposis	8
Fulminant immune-related colitis after dual checkpoint inhibitor therapy: case report	8

Impact of Helicobacter Pylori Infection on The Efficacy of Immune Checkpoint Inhibitors for Cancer Treatment: A Meta-Analysis	7
Combination of Methotrexate with Oral Disease-Modifying Antirheumatic Drugs in Psoriatic Arthritis: A Systematic Review	7
Established and Emerging Biomarkers of Immunotherapy in Renal Cell Carcinoma	7
Upadacitinib for the Treatment of Moderate-to-Severe Crohn’s Disease	7
Optimizing TIL therapy for uveal melanoma: lessons learned and unlearned from cutaneous melanoma	7
Lebrikizumab decreases type 2 inflammatory biomarker levels in patients with asthma: data from randomized phase 3 trials (LAVOLTA I and II)	7
Immunotherapies for prevention and treatment of type 1 diabetes	7
Long-Term Response to Camrelizumab in a Pretreated Metastatic Mixed Testicular Germ-Cell Tumor Patient with Co-Mutations in DNA Damage-Repair Genes	7
Simultaneous Inhibition of PD-1 and LAG-3: the Future of Immunotherapy?	7
Abrocitinib for the Treatment of Atopic Dermatitis	7
An Abscopal Effect in a Gastric Cancer Patient Treated with Combined Chemoimmunotherapy and Palliative Radiotherapy	7
Venous Thromboembolism Events in Patients with Advanced Cancer on Immune Checkpoint Inhibitors	7
Validating Khorana Risk Score in gastric cancer patients on immune checkpoint inhibitors and chemotherapy	7
Cost-effectiveness of Upadacitinib vs. Tofacitinib for moderate-to-severe rheumatoid arthritis in China	7
Pembrolizumab in an HIV-infected patient with glioblastoma	7
Evaluating Axatilimab as a treatment option for chronic graft-versus-host disease	6
Amlitelimab, an anti-OX40 ligand antibody, for atopic dermatitis: a plain language summary of STREAM-AD clinical study	6
Indications and Effects of Biological Agents in the Treatment of Noninfectious Uveitis	6
Updated Insights on Cardiac Risks of CD19-Directed Chimeric Antigen Receptor T-cell Therapy: A Pharmacovigilance Study	6
Fractional Exhaled Nitric Oxide in Checkpoint Inhibitor Pneumonitis: A Case Report and Literature Review	6
An Unusual Case of Immune-Related Gastritis in One Patient Receiving Toripalimab Therapy	6
Mitigation strategies for gastrointestinal (GI) immune-related adverse events for patients with solid tumors receiving immunotherapy	6
A novel dose-adjustment protocol for interrupted subcutaneous immunotherapy in children with allergic rhinitis	6
Plain Language Summary of principles for improving the care of people with eosinophil-associated diseases	6
Could senescent cells be the prescription for therapeutic cancer vaccines?	6
Cutaneous Metastases at the Sites of Pembrolizumab-Induced Bullous Pemphigoid Lesions in a Patient with Melanoma	6
Prognostic value of type of prior TKI in pretreated metastatic renal cell carcinoma patients receiving nivolumab	6
Intratumoral Delivery of Immune Therapy and Gene Therapy: The Next Era for Cancer Therapy	6
Ocular Toxicities in Chimeric Antigen Receptor T-Cell Therapy: A Real-World Study Leveraging FAERS Database	6
Application of immune checkpoint inhibitors in immunotherapy for gastric cancer	6
Moving Beyond Single-Agent Checkpoint Inhibition in Biliary Tract Cancers: What is the Next Frontier?	6
Treatment of EAE Mice with Treg, G-MDSC and IL-2: a New Insight into Cell Therapy for Multiple Sclerosis	6
Treatment of Plaque Psoriasis with Deucravacitinib (Poetyk Pso-2 Study): A Plain Language Summary	6
Paraneoplastic dermatomyositis and Stevens-Johnson syndrome related to immunotherapy	6
Mirikizumab for the Treatment of Moderate to Severe Ulcerative Colitis	6
Pathological Findings Directing Immunotherapy in Renal Cell Carcinomas	6
Treatment patterns and outcomes in melanoma brain metastasis: exploring immune-related adverse events and survival	6
Evaluating the Effectiveness of the Charlson Comorbidity Index in Predicting Immune Checkpoint Inhibitor-Related Adverse Events	6
Allogeneic CAR-T cells for cancer immunotherapy	6
The Development of Litifilimab (BIIB 059) for Cutaneous and Systemic Lupus Erythematosus	6
A New Perspective on The Potential Application of Ripk1 in the Treatment of Sepsis	6
Oncolytic Viruses in Lung Cancer Treatment: A Review Article	6
Immunotherapeutic effects of TCL-E5 and TCL-E5-pulsed DCs: two novel HPV therapeutic vaccine candidates	6
Effect of Helicobacter Pylori infection on immunotherapy for gastrointestinal cancer: a narrative review	5
Pegcetacoplan Treatment for Geographic Atrophy Due to Age-Related Macular Degeneration: A Plain Language Summary of the FILLY Study	5
Anaphylaxis to Tocilizumab in Patients with Rheumatic Disease	5
Gamma heavy chain disease treated with daratumumab-based regimen: a first case report and review of literature	5
The Effect of Low-Dose Chemotherapy on the Tumor Microenvironment and its Antitumor Activity Combined with Anti-PD-1 Antibody	5
Pd-1/L1 Inhibitors May Increase the Risk of Pericardial Disease in Non-Small-Cell Lung Cancer Patients: A Meta-Analysis and Systematic Review	5
Impact of low sodium values on survival outcomes of patients with cancer receiving immune checkpoint inhibitors	5
Prognostic immunoinflammatory and transcriptomic profiles in patients with pleural mesothelioma undergoing immunotherapy	5
Real-World Study: Drug Reduction in Children With Allergic Rhinitis and Asthma Receiving Immunotherapy	5
The Use of Dostarlimab, a Safe and Efficient Monotherapy in Msi-H Rectal Cancer Patients, an Alternative to Surgery	5
Sarcoidosis-like reactions in metastatic renal cell carcinoma patients treated with immune-based combinations	5
A patient empowerment program for primary immunodeficiency improves quality of life in children and adolescents	5
Peptide–MHC Complexes: Dressing up to Manipulate T Cells Against Autoimmunity and Cancer	5
Safety and Effectiveness of a 300 IR House Dust Mite Sublingual Tablet: Descriptive 4-Year Final Analysis of a Post-Marketing Surveillance in Japan	5
Amalgamation of Nanotechnology with Chicken IgY to Enrich Therapeutic and Diagnostic Applications: A Systematic Review	5
Peripheral Blood Eosinophil Count is Associated with Response to Chemoimmunotherapy in Metastatic Triple-Negative Breast Cancer	5
Positioning risankizumab in the treatment algorithm of moderate-to-severe Crohn's disease	5
Summary of Certolizumab Pegol in Psoriasis Including Structural Features, Pharmacokinetics and Treatment	5
Pancreas-specific immune-related adverse events in patients with lung cancer: a case series study	5
Tsunami of Immunotherapies in the Management of Esophageal Cancer	5
A CD123-Specific Chimeric Antigen Receptor Augments Anti-Acute Myeloid Leukemia Activity of Vγ9Vδ2 T Cells	5
ICAM2 is Related to Good Prognosis in Dendritic Cell Immunotherapy for Cancer	5
Targeting the Tumor Microenvironment of Ewing Sarcoma	5
Infrequent Liver Injury from Cemiplimab in Patients with Advanced Cutaneous Squamous Cell Carcinoma	5
Neoadjuvant Immunochemotherapy in the Treatment of Nonmetastatic Muscle-Invasive Bladder Cancer: A Systematic Review	5
Radiation and Resolve: Unlocking the Synergistic Potential of Radioimmunotherapy in Advanced Lung Cancer Management	5
Efficacy of Long-Term Repeated Rituximab Treatment in Refractory Phospholipase A2 Receptor-Antibody-Related Membranous Nephropathy	5
A Trispecific Antibody Induces Potent Tumor-Directed T-Cell Activation and Antitumor Activity by CD3/CD28 Co-Engagement	5
Pembrolizumab: A New Standard of Care in Metastatic Colorectal Cancer	5