Epigenomics

Article	Citations
CRISPR-Based Epigenome Editing: Mechanisms and Applications	44
Integrated Analysis Revealing the Role Of TET3-Mediated MUC13 Promoter Hypomethylation in Hepatocellular Carcinogenesis	33
A Comprehensive Bioinformatic Analysis of RanBP9 Expression and Its Relation to Prognosis in Human Breast Cancer	32
The Era of Biomarkers and Precision Medicine in Colorectal Cancer: An Interview with Ajay Goel	27
LncRNA H19 Promotes Tumor Angiogenesis in Smokers by Targeting Anti-Angiogenic MiRNAs	27
Specific Epigenetic age Acceleration Patterns Among Four Molecular Subtypes of Gastric Cancer and their Prognostic Value	25
Fatty Acid Metabolism-Related lncRNA Prognostic Signature for Serous Ovarian Carcinoma	22
Pathological Epigenetic Events and Reversibility Review: the Intersection between Hallmarks of Aging and Developmental Origin of Health and Disease	21
Epigenetic landscape of intestinal cell line HT29 cocultured with Lacticaseibacillus	20
Changes of BDNF exon IV DNA methylation are associated with methamphetamine dependence	20
Toward a more holistic approach to the study of exposures and child outcomes	19
A Step Towards Understanding Disparities – Linking Race, Ancestry, Epigenetics and Pain	19
Novel epigenetic roles of lactylation in osteogenesis	19
Epigenetics of cerebrovascular diseases: an update review of clinical studies	18
FAM81A Identified as a Stemness-Related Gene by Screening DNA Methylation Sites Based on Machine Learning-Accessed Stemness in Pancreatic Cancer	17
Role of Epigenetics in Pancreatic Ductal Adenocarcinoma	17
Epigenetic Studies of Child Neurodevelopment: What can we Learn from a Developmental Science Perspective?	16
Epigenetic Signature Discriminates Lymphatic Metastasis in BRAF Wild-Type Thyroid Carcinoma: Methylation Role of GRIK2	16
Lessons in Chromatin Organization and Gender Equity in Research: An Interview with Susan Gasser	15
Secretion of Acetylated Amino Acids by Drug-Induced Cancer Cells: Perspectives on Metabolic-Epigenetic Alterations	15
Emerging Functions and Roles of circRNAs in Cancer	15
Epigenetic Disruption of Histone Deacetylase-2 Accelerated Apoptotic Signaling and Retarded Malignancy in Gastric Cells	14
Hypomethylation of Wnt Signaling Regulator Genes in Developmental Language Disorder	14
Exploring the Pathogenesis and Treatment of IgA Nephropathy Based on Epigenetics	14
Methylation Quantitative Trait Locus Analysis of Chronic Postsurgical Pain Uncovers Epigenetic Mediators of Genetic Risk	13

Identification of Potential Differentially Methylated Gene-Related Biomarkers in Endometriosis	13
Epigenomics May Begin To Explain In Vitro Differential Response To Hypomethylating Agents In MMR-D Hypermethylated Endometrial Cancer	13
Leveraging Epigenetics to Enhance the Efficacy of Cancer-Testis Antigen: A Potential Candidate for Immunotherapy	13
Epigenetic Regulation of Vitamin D Deficiency	13
The Link Between 5-Hydroxymethylcytosine and DNA Demethylation in Early Embryos	13
A method of sample-wise region-set enrichment analysis for DNA methylomics	13
Combination Therapy and Noncoding RNAs: A New Era of Cancer Personalized Medicine	13
Mycotoxins Exacerbate HIV Infection: The Potential of N 6 -Methyladenosine RNA Methylation	12
A novel subtype to predict prognosis and treatment response with DNA driver methylation–transcription in ovarian cancer	12
SPARCL1 Exhibits Different Expressions in Left- and Right-Sided Colon Cancer and is Downregulated Via DNA Methylation	12
Epigenetic Signature of Exposure to Maternal Trypanosoma Cruzi Infection in Cord Blood Cells from Uninfected Newborns	12
Welcome to the 14th Volume of Epigenomics	12
A novel chromatin regulator signature predicts the prognosis, clinical features and immunotherapy of colon cancer	12
DNMT3L Interacts with Piwi and Modulates the Expression of piRNAs in Transgenic Drosophila	11
Precision Epigenetics Provides a Scalable Pathway for Improving Coronary Heart Disease Care Globally	11
Influence of Antidepressant Drugs on DNA Methylation of Ion Channels Genes in Blood Cells of Psychiatric Patients	11
DNA Methylation Detection Technology and Plasma-Based Methylation Biomarkers in Screening of Gastrointestinal Carcinoma	11
Decoding the Year of 2023: Welcome to the 16th Volume of Epigenomics	11
Global DNA Hypomethylation and the Expression Profile of DNA Methyltransferase Genes in Late-Onset Neonatal Sepsis	11
Prenatal Neun+ Neurons of Down Syndrome Display Aberrant Integrative DNA Methylation and Gene Expression Profiles	11
DNA methylation in chronic obstructive pulmonary disease	11
EpigenomIc Technologies: An Interview with Jörg Tost	11
Unlocking the Epigenetic Symphony: Histone Acetylation’s Impact on Neurobehavioral Change in Neurodegenerative Disorders	11
Epigenome-Scale Comparison of DNA Methylation Between Blood Leukocytes and Bronchial Epithelial Cells	10
The Role of H3K9 Acetylation and Gene Expression in Different Brain Regions of Alzheimer’s Disease Patients	10
The Conundrum of the Functional Relationship Between Transcription Factors and Chromatin	10
Histone Deacetylase 6: At the Interface of Cancer and Neurodegeneration	10
Genome-wide Methylation Analysis of Post-Mortem Cerebellum Samples Supports the Role of Peroxisomes in Autism Spectrum Disorder	10
Apoptosis And Myocardial Infarction: Role Of Ncrnas And Exosomal Ncrnas	10
Gut Microbiota and Epigenetics in Colorectal Cancer: Implications for Carcinogenesis and Therapeutic Intervention	9
Association between Alcohol Consumption and DNA Methylation in Blood: A Systematic Review of Observational Studies	9
Epigenetic Age Associates with Psychosocial Stress and Resilience in Children of Latinx Immigrants	9
Dna Methylation Episignatures are Sensitive and Specific Biomarkers for Detection of Patients with Kat6A / Kat6B Variants	9
The regulation of microRNAs on chemoresistance in triple-negative breast cancer: a recent update	9
DNA methylation episignatures: insight into copy number variation	9
Epigenetics-Based Diagnostic and Therapeutic Strategies: Shifting the Paradigm in Prostate Cancer	9
Epigenetic identification of LTBP4 as a putative tumor suppressor in breast cancer	9
Altered epigenetic landscape as infectious disease diagnostics	9
miR-498 inhibits autophagy and M2-like polarization of tumor-associated macrophages in esophageal cancer via MDM2/ATF3	9
The Significance of Studying Functional Lncrna in Mouse Spermatogenesis	9
Statin therapy is associated with epigenetic modifications in individuals with Type 2 diabetes	9
Gestational Sleep Apnea Perturbations Induce Metabolic Disorders by Divergent Epigenomic Regulation	9
Bridging the gap: R-loop mediated genomic instability and its implications in neurological diseases	9
Toxicoepigenetic Consequences of Fumonisin B 1 Exposure: Current Knowledge and Future Perspective	8
Retraction: Inhibition of CTCF-Regulated miRNA-185-5p Mitigates Renal Interstitial Fibrosis of Chronic Kidney Disease	8
Epitranscriptomic Analysis of m 6 A Methylome in Rats after Lumbosacral Nerve Root Avulsion	8
HAR1 : An Insight Into lncRNA Genetic Evolution	8
Impact of prematurity on LINE-1 promoter methylation	8
Association between epigenetic aging and atrioventricular block: a two-sample Mendelian randomization study	8
Super-enhancers: drivers of cells’ identities and cells’ debacles	8

Potential epigenetic markers of clinical diagnostics/therapeutic targets in preeclampsia	7
Transcriptome Profiling and ceRNA Network of Small Extracellular Vesicles from Resting and Degranulated Mast Cells	7
Hsa_Circ_0092339 Acts as a Molecular Sponge in Castration-Resistant Prostate Cancer via the Hsa-Mir-940/ C-MYC Axis	7
Distinct Cytosine Modification Profiles Define Epithelial-to-MesenChymal Cell-State Transitions	7
Cellular and epigenetic perspective of protein stability and its implications in the biological system	7
Expression profiles and functional analysis of plasma tRNA-derived small RNAs in children with fulminant myocarditis	7
Coregulatory effects of multiple histone modifications in key ferroptosis-related genes for lung adenocarcinoma	7
lncRNA TUG1 as Potential Novel Biomarker for Prognosis of Cardiovascular Diseases	7
Promoter hypermethylation of Y-chromosome gene PRKY as a potential biomarker for the early diagnosis of prostate cancer	7
Advances in DNA methylation of imprinted genes and folic acid regulation of growth and development	7
Breaking the epigenetic code with MARCS: the Modification Atlas of Regulation by Chromatin States	7
Genome-wide associations between alcohol consumption and blood DNA methylation: evidence from twin study	7
Comparison of DNA Methylation Clocks in Black South African Men	6
Complex Cross-Talk between EZH2 and Mirnas Confers Hallmark Characteristics and Shapes the Tumor Microenvironment	6
Epigenetic Mechanisms Underpinning Sexual Dimorphism in Lung Disease	6
DNMT3a Promotes Osteoblast Differentiation and Alleviates Osteoporosis Via the PPARγ / SCD1 / GLUT1	6
Alteration of the N 6 -Methyladenosine Epitranscriptomic Profile in Synthetic Phthalate-Treated Human Induced Pluripotent Stem Cell-Derived Endothelial Cells	6
Mirnas as Biomarkers of Musculoskeletal Pain in Long-Distance Runners: The Mimus Study Protocol	6
Integrated Analysis of tRNA-Derived Small RNAs Reveals New Therapeutic Genes of Hyperbaric Oxygen in Diabetic Foot Ulcers	6
Phytochemicals in Cervical Cancer: An Epigenetic Overview	6
Comparative Epigenome-Wide Analysis Highlights Placenta-Specific Differentially Methylated Regions	6
Role of long non-coding RNAs in neurofibromatosis and Schwannomatosis: pathogenesis and therapeutic potential	6
Clinical Uses of Epigenetics in Cardiology and Cardiothoracic Surgery: An Update	6
Quantum Leap: Is the Conflux of Artificial Intelligence, Personalized Medicine, Nutrigenetics and Nutrigenomics the Path to Optimal Health?	6
The Epigenetic Impact of Adverse Childhood Experiences Through the Lens of Personalized Medicine	6
Sex- and Tissue-Specific Effects of Binge-Level Prenatal Alcohol Consumption on DNA Methylation at Birth	5
Promotional Effects of HIF1α and KDM3A Interaction on Vascular Smooth Muscle Cells in Thoracic Aortic Dissection	5
Could unlocking methylation-based blood cell counts revolutionize epidemiology?	5
The hMeDIP-Seq Identified  INPP4A as a Novel Biomarker for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps	5
Epigenomic Impacts of Meditative Practices	5
The Impact and Mechanism of TET3 Overexpression on the Progression of Hepatic Fibrosis	5
Value of CtDNA Methylation Biomarkers in Diagnosis of Colorectal Tumors	5
How does m 6 A Regulation Affect the Differentiation and Fate of Embryonic Stem Cells?	5
The Diagnostic Potential of the Epigenome in Autism Spectrum Disorders	5
The Legacy Is Not Just With You: An Interview With Stephen Baylin	5
RUNX1 Methylation as a Cancer Biomarker in Differentiating Papillary Thyroid Cancer from Benign Thyroid Nodules	5
Deep Characterization of Paired Chromatin and Transcriptomes in Four Immune Cell Types from Multiple Sclerosis Patients	5
NTRK Genes and Cancer: when Arresting the Fusion Underlies the Treatment	5
Methylated ZNF582: a therapeutic target in oral cancer	5
Decoding Mitochondrial–Nuclear (epi)genome Interactions: The Emerging Role of ncRNAs	5
PEMT Variants are Associated with Nonsyndromic Cleft Lip with or without Cleft Palate in Chile	5
Identification of Histone Acetylation Modification Sites in the Striatum of Subchronically Manganese-Exposed Rats	5
How do Sphingolipids Play a Role in Epigenetic Mechanisms and Gene Expression?	5
The Study of HMOX1 DNA Methylation and Gene Expression and the Diagnostic Potential of miR-153-3p in Preeclampsia	5
Twin Study: Genotype-Dependent Epigenetic Factors Affecting Free Thyroxine Levels in the Normal Range	5
Alteration of DNA Methyltransferases by Eribulin Elicits Broad DNA Methylation Changes with Potential Therapeutic Implications for Triple-Negative Breast Cancer	5
Exploring Epigenetic Biomarkers of Universal Specificities and Commonalities Among Pan-Cancer Cohorts in The Cancer Genome Atlas	5
Identification of Tissue of Origin in Cancer of Unknown Primary using a Targeted Bisulfite Sequencing Panel	5
SET Protein as an Epigenetics Target	5
Beyond the Transcription Factor: The Under-Studied Role of Epigenomics in Lung Differentiation	5
The Ups and Downs of DNA Methylation: An Interview with Gerd Pfeifer	5
Breast Milk-Derived Extracellular Vesicle Mirnas are Associated with Maternal Asthma and Atopy	4
Exosomal miRNAs in Urine Associated with Children’s Cardiorenal Parameters: a Cross-Sectional Study	4
Epigenomics in COVID-19; the Link Between DNA Methylation, Histone Modifications and SARS-CoV-2 Infection	4
Association of Grandmaternal Smoking During Pregnancy with DNA Methylation of Grandchildren: the Isle of Wight Study	4
Transcriptome-Wide N6-Methyladenosine Methylation Landscape of Coronary Artery Disease	4
Epigenome-Wide Studies of Antipsychotics: A Systematic Review and Pathway Meta-Analysis	4
Early life trauma, DNA methylation and mental illness	4
How Epigenomics Broke the Mold: An Interview with Peter W Laird	4
Methylation of TMEM176A , a key ERK Signaling Regulator, is a Novel Synthetic Lethality Marker of ATM Inhibitors in Human Lung Cancer	4
Construction of a prognostic model based on genome-wide methylation analysis of miRNAs for hepatocellular carcinoma	4
Comparison of Methylation Episignatures in KMT2B - and KMT2D -Related Human Disorders	4
Anoikis-Associated Signatures Predict Prognosis and Immune Response in Bladder Cancer	4
DNA Methylation as the Link between Migration and the Major Noncommunicable Diseases: the RODAM Study	4
Epigenomics in the single cell era, an important read out for genome function and cell identity	4
Induced Pluripotent Stem Cell Technology: Trends in Molecular Biology, from Genetics to Epigenetics	4
Epigenetic axis of SNHG19/miR-137/TNFAIP1 modulates amyloid beta peptide 25–35-induced SH-SY5Y cytotoxicity	4
NEAT1 Functions as a Key Mediator of BMP2 to promote osteogenic differentiation of renal interstitial fibroblasts	4
Epigenetics and Cutaneous Neoplasms: From Mechanism to Therapy	4
Epigenetics and its Therapeutic Potential in Colorectal Cancer	4
Evaluating the Clinical Performance of SDC2/NDRG4 Methylation for Colorectal Cancer Detection	4
Covid-19 And Cancer: Insights Into Their Association And Influence On Genetic And Epigenetic Landscape	4
Age-Related Changes in Sperm DNA Methylation and their Forensic and Clinical Implications	3
tRNA-derived RNAs in human milk extracellular vesicles and associations with breastfeeding variables and maternal diet	3
Placental expression and methylation of angiogenic factors in assisted reproductive technology pregnancies from India	3
Cell-Free DNA Methylation as a Potential Biomarker in Brain Disorders	3
Epigenetics in the AnthropoCene: An Interview with Oskar Karlsson	3
DNA Methylation as a Window into Female Reproductive Aging	3
The mystique of epigenetic regulation: the remarkable case of a human noncoding RNA, nc886	3
Epigenomic newborn screening for conditions with intellectual disability and autistic features in Australian newborns	3

Low Expression Levels of miRNA-155 and miRNA-499a are Associated with Obesity in Type 2 Diabetes	3
Stress and Spirituality in Relation to HPA Axis Gene Methylation Among US Black women: Results from the Black Women’s Health Study and the Study on Stress, Spirituality and Health	3
DDR1 methylation is associated with bipolar disorder and the isoform expression and methylation of myelin genes	3
The Contribution of Ethnography to Epigenomics Research: Toward a New Bio-Ethnography for Addressing Health Disparities	3
Comprehensive Analysis of Epigenetic Modifications and Immune-Cell Infiltration In Tissues from Patients With Systemic Lupus Erythematosus	3
Neonatal necrotizing enterocolitis-associated DNA methylation signatures in the colon are evident in stool samples of affected individuals	3
Epigenetic rejuvenation: a journey backwards towards an epigenomic ground state	3
The Prognostic Value and Biological Functions of HFM1 in Breast Cancer	3
mRNA Modifications: Clinical Clarification and Significance	3
POU2F2-mediated Upregulation of lncRNA PTPRG-AS1 Inhibits Ferroptosis in Breast Cancer Via miR-376c-3p/SLC7A11 Axis	3
Comprehensive analysis of differentially expressed long noncoding RNAs, miRNAs and mRNAs in breast cancer brain metastasis	3
Gastric microbiome composition accompanied with the Helicobacter pylori related DNA methylation anomaly	3
An Immune Epigenetic Insight to COVID-19 Infection	3
SIX4 , a Potential Therapeutic Target for Estrogen Receptor-Positive Breast Cancer Patients, is Associated with low Promoter Methylation Level	3
Essential Amino Acid Metabolism-Related Molecular Classification in Triple-Negative Breast Cancer	3
NR3C1 gene methylation and cortisol levels in preterm and healthy full-term infants in the first 3 months of life	3
Methylome of Skeletal Muscle Tissue in Patients with Hypertension and Diabetes Undergoing Cardiopulmonary Bypass	3
The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery	3
Gene Regulation in Animal miRNA Biogenesis	3
Emergent properties of the lysine methylome reveal regulatory roles via protein interactions and histone mimicry	3
An Epigenetic Synopsis of Parental Substance Use	3
Epigenetics, Environment and Epidemiology: An Interview with Karl Kelsey	3
Matched Analysis of Detailed Peripheral Blood and Tumor Immune Microenvironment Profiles in Bladder Cancer	3
Cataloging Recent Advances in Epigenetic Alterations in Major Mental Disorders and Autism	3
circRNA: A Promising All-Around Star in the Future	3
Comprehensive analysis of ESR1 -related ceRNA axis as a novel prognostic biomarker in hepatocellular carcinoma	3
BRCA2 Promoter Hypermethylation as a Biomarker for the Leukemic Transformation of Myeloproliferative Neoplasms	3
Introducing the Research Article Reporting Checklist for Bioinformatic and Data Re-Analysis Studies	3
DNA Methylation Mediates the Genetic Variants on Ticagrelor Major Metabolite Elimination and Platelet Function Recovery after Ticagrelor Discontinuation	3
Multi-omics insights into the pathogenesis of diabetic cardiomyopathy: epigenetic and metabolic profiles	3
The fate and function of non-coding RNAs during necroptosis	2
Deciphering KDM8 dysregulation and CpG methylation in hepatocellular carcinoma using multi-omics and machine learning	2
A Preliminary Analysis of LncRNA Biomarkers for Schizophrenia	2
Detecting Differentially Methylated Regions with Multiple Distinct Associations	2
Cell-Specific Epigenetic Drivers of Pathogenesis in Rheumatoid Arthritis	2
Prenatal chemical exposures and the methylome: current evidence and opportunities for environmental epigenetics	2
Genome-Wide Temporal Landscaping of DNA Methylation in Pregnant Women Delivering at Term: A GARBH-Ini Study	2
A comprehensive review on the functional role of miRNA clusters in cervical cancer	2
Clinically Informative Micrornas for SARS-CoV-2 Infection	2
Comprehensive Methylation Profile of CSF cf DNA Revealed Pathogenesis and Diagnostic Markers for Early-Onset Parkinson’s Disease	2
Histone methylation in Epstein–Barr virus-associated diseases	2
Artificial Neural Networks Reveal Sex Differences in Gene Methylation, and Connections Between Maternal Risk Factors and Symptom Severity in Autism Spectrum Disorder	2
Environmental aging: through the prism of DNA methylation	2
Evaluating the Challenges and Reproducibility of Studies Investigating DNA Methylation Signatures of Psychological Stress	2
A Regulative Epigenetic Circuit Supervised by HDAC7 Represses IGFBP6 and IGFBP7 Expression to Sustain Mammary Stemness	2
hsa_circ_0087100/hsa-miR-6743-5p affects Th1 cell differentiation by regulating STAT1 in diabetic retinopathy	2
High methylation of the same promoter of lncRNA ZNF582-AS1 / ZNF582 promotes malignant progression of esophageal cancer	2
Risks and Rewards of Big-Data in Epigenomics Research: An Interview with Melanie Ehrlich	2
Roles of Noncoding RNAs in the Initiation and Progression of Myocardial Ischemia-Reperfusion Injury	2
DNMT1: catalytic and non-catalytic roles in different biological processes	2
Stable methylation loci are associated with systolic blood pressure in a Croatian island population	2
Key lncRNAs Involved in Ischemic Strokes	2
Methylated Ccfdna from Plasma Biomarkers of Alzheimer’s Disease Using Targeted Bisulfite Sequencing	2
The eighth annual US DOHAD meeting: promising approaches in epigenetics research of early life exposures	2
Combining EZH2 inhibitors with other therapies for solid tumors: more choices for better effects	2
Functional Analysis of PCSK9 3′UTR Variants and mRNA–miRNA Interactions in Patients with Familial Hypercholesterolemia	2
ARID1 Proteins: from Transcriptional and Post-Translational Regulation to Carcinogenesis and Potential Therapeutics	2
Methylation changes of liver DNA during the formation of gallstones	2
LINC01133 Hampers the Development of Gastric Cancer Through Increasing Somatostatin via Binding to microRNA-576-5p	2
Advances in the Role of Epigenetics in Homocysteine-Related Diseases	2
HDL-enriched miR-30a-5p is associated with HDL-cholesterol levels and glucose metabolism in healthy men and women	2
Identification of Three lncRNA-Related Prognostic Signatures in Gastric Cancer by Integrated Multi-Omics Analysis	2
Performance Comparisons of Methylation and Structural Variants From Low-Input Whole-Genome Methylation Sequencing	2
Insights to aging prediction with AI based epigenetic clocks	2
Current trends in clinical trials and the development of small molecule epigenetic inhibitors as cancer therapeutics	2
The Multiple Faces of NANOG in Cancer: A Therapeutic Target to Chemosensitize Therapy-Resistant Cancers	2
Blocking RPA-based methods for the determination of CpG methylation status and detection of gene mutations	2
A novel methylated cell-free DNA marker panel to monitor treatment response in metastatic prostate cancer	2
Circular RNAs as multifaceted molecular regulators of vital activity and potential biomarkers of aging	2
Alteration of the m 6 A Methylation Landscape in a Mouse Model of Scleroderma	2
DNA methylation marker identification and poly-methylation risk score in prediction of healthspan termination	2
High Serum miR-421 is Associated with Metabolic Dysregulation and Inflammation in Patients with Metabolic Syndrome	2
Harnessing the Role of Epigenetic Histone Modification in Targeting Head and Neck Squamous Cell Carcinoma	2
Combined therapy targeting AR and EZH2 curbs castration-resistant prostate cancer enhancing anti-tumor T-cell response	2
Pyroptosis-Related Lncrna Prognostic Signatures for Cutaneous Melanoma and Tumor Microenvironment Status	2
Predicting locus-specific DNA methylation levels in cancer and paracancer tissues	2
Human RNA-Directed DNA Methylation Methylates High-Mobility Group Box 1 Protein-Produced DNA Gaps	2
Ubiquitination and SUMOylation: Protein Homeostasis Control Over Cancer	2
The Role of EZH2 in Ocular Diseases: A Narrative Review	2
MeCP2 is the Protector of Epigenome Integrity, Membrane-Less Nuclear Architecture, and Stability of Chromatin Assembly	2