Epigenomics

Article	Citations
Exosomal microRNAs: novel players in cervical cancer	62
Analysis of exosomal lncRNA, miRNA and mRNA expression profiles and ceRNA network construction in endometriosis	42
CircRNA hsa_circ_0004771 promotes esophageal squamous cell cancer progression via miR-339-5p/CDC25A axis	42
Antagomir technology in the treatment of different types of cancer	39
miRNA in prostate cancer: challenges toward translation	39
Radiotherapy-induced overexpression of exosomal miRNA-378a-3p in cancer cells limits natural killer cells cytotoxicity	33
EZH2 inhibition: a promising strategy to prevent cancer immune editing	33
Potential use of noncoding RNAs and innovative therapeutic strategies to target the 5’UTR of SARS-CoV-2	31
An immune epigenetic insight to COVID-19 infection	31
RNA N-6-methyladenosine enzymes and resistance of cancer cells to chemotherapy and radiotherapy	28
hsa_circ_0001947 suppresses acute myeloid leukemia progression via targeting hsa-miR-329-5p/CREBRF axis	28
Long noncoding RNA KTN1-AS1 promotes head and neck squamous cell carcinoma cell epithelial–mesenchymal transition by targeting miR-153-3p	23
Per- and polyfluoroalkyl substances, epigenetic age and DNA methylation: a cross-sectional study of firefighters	22
Epigenetic biomarkers for human sepsis and septic shock: insights from immunosuppression	21
Dynamic analysis of m6A methylation spectroscopy during progression and reversal of hepatic fibrosis	21
Epigenetic aging as a biomarker of dementia and related outcomes: a systematic review	21
The inter-talk between Mycobacterium tuberculosis and the epigenetic mechanisms	21
Prediction of transcription factors binding events based on epigenetic modifications in different human cells	20
LncRNA AC245100.4 binds HSP90 to promote the proliferation of prostate cancer	20
Alteration of N6-methyladenosine epitranscriptome profile in unilateral ureteral obstructive nephropathy	20
The influence of lifestyle factors on miRNA expression and signal pathways: a review	20
Expression study of candidate miRNAs and evaluation of their potential use as biomarkers of diabetic neuropathy	19
Long noncoding RNAs expression profile and long noncoding RNA-mediated competing endogenous RNA network in nonobstructive azoospermia patients	19
Bioinformatics analysis integrating metabolomics of m6A RNA microarray in intervertebral disc degeneration	19
A transdisciplinary approach to understand the epigenetic basis of race/ethnicity health disparities	19

Multi-omics analysis based on integrated genomics, epigenomics and transcriptomics in pancreatic cancer	19
DNMT1: catalytic and non-catalytic roles in different biological processes	18
High-throughput miRNA sequencing of the human placenta: expression throughout gestation	18
RNA-Seq profiling of circular RNAs in human small cell lung cancer	17
Construction of a lncRNA–miRNA–mRNA network to determine the key regulators of the Th1/Th2 imbalance in multiple sclerosis	17
Eight-gene prognostic signature associated with hypoxia and ferroptosis for gastric cancer with general applicability	17
A role for microRNAs in the epigenetic control of sexually dimorphic gene expression in the human placenta	17
H19 promotes the gastric carcinogenesis by sponging miR-29a-3p: evidence from lncRNA–miRNA–mRNA network analysis	17
LncRNA HCG18 suppresses CD8+ T cells to confer resistance to cetuximab in colorectal cancer via miR-20b-5p/PD-L1 axis	17
Epigenetic regulation of adipogenesis by histone-modifying enzymes	16
LncRNA HORAS5 promotes taxane resistance in castration-resistant prostate cancer via a BCL2A1-dependent mechanism	16
Intergenerational effects of maternal post-traumatic stress disorder on offspring epigenetic patterns and cortisol levels	16
DNA methylation analysis of candidate genes associated with dementia in peripheral blood	16
Epigenetics and expression of key genes associated with cardiac fibrosis:NLRP3, MMP2, MMP9, CCN2/CTGFandAGT	16
Prefrontal cortex eQTLs/mQTLs enriched in genetic variants associated with alcohol use disorder and other diseases	15
Evaluation of six methylation markers derived from genome-wide screens for detection of cervical precancer and cancer	15
Unleash multifunctional role of long noncoding RNAs biomarker panel in breast cancer: a predictor classification model	15
miRNA-148b and its role in various cancers	15
Transcriptome hallmarks in Helicobacter pylori infection influence gastric cancer and MALT lymphoma	15
CpG-methylation-based risk score predicts progression in colorectal cancer	14
Circular RNA expression profile and m6A modification analysis in poorly differentiated adenocarcinoma of the stomach	14
miR-498 inhibits autophagy and M2-like polarization of tumor-associated macrophages in esophageal cancer via MDM2/ATF3	14
Epigenetic mechanisms activated by childhood adversity	14
The growing landscape of succinylation links metabolism and heart disease	14
A novel mechanism of intervertebral disc degeneration: imbalance between autophagy and apoptosis	14
Social epigenomics: are we at an impasse?	14
Hypermethylated promoters of genes UNC5D and KCNA1 as potential novel diagnostic biomarkers in colorectal cancer	14
Epigenomics in COVID-19; the link between DNA methylation, histone modifications and SARS-CoV-2 infection	14
A combination of methylation and protein markers is capable of detecting gastric cancer detection by combined markers	13
Microbial regulation of a lincRNA–miRNA–mRNA network in the mouse hippocampus	13
Epigenetic modulation of autophagy genes linked to diabetic nephropathy by administration of isorhamnetin in Type 2 diabetes mellitus rats	13
Identification of tRNA-derived fragments and their potential roles in diabetic cataract rats	13
Circular RNA expression profiles and bioinformatic analysis in coronary heart disease	13
DNA methylation events in transcription factors and gene expression changes in colon cancer	13
Early-life stress induces genome-wide sex-dependent miRNA expression and correlation across limbic brain areas in rats	13
Transcriptome-wide N6-methyladenosine methylation landscape of coronary artery disease	13
RNA sequencing of exosomes revealed differentially expressed long noncoding RNAs in early-stage esophageal squamous cell carcinoma and benign esophagitis	13
Epigenetics of neuromuscular disorders	12
The multiple faces of NANOG in cancer: a therapeutic target to chemosensitize therapy-resistant cancers	12
CRISPR-mediated modification of DNA methylation pattern in the new era of cancer therapy	12
ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics	12
Circular RNA profile in diabetic peripheral neuropathy: analysis of coexpression networks of circular RNAs and mRNAs	12
Transcriptomic and epigenomics atlas of myotubes reveals insight into the circadian control of metabolism and development	12
CLDN10 associated with immune infiltration is a novel prognostic biomarker for clear cell renal cell carcinoma	12
Differentially expressed urinary exo-miRs and clinical outcomes in kidney recipients on short-term tacrolimus therapy: a pilot study	12
Radiologically isolated syndrome: targeting miRNAs as prognostic biomarkers	12
Sex-specific DNA methylation differences in people exposed to polybrominated biphenyl	12
Melatonin and regulation of miRNAs: novel targeted therapy for cancerous and noncancerous disease	12
Altered PTPRD DNA methylation associates with restricted adipogenesis in healthy first-degree relatives of Type 2 diabetes subjects	12
Identification of prognostic biomarkers of hepatocellular carcinoma via long noncoding RNA expression and copy number alterations	12

Dynamics of the cell-free DNA methylome of metastatic prostate cancer during androgen-targeting treatment	12
Detecting differentially methylated regions with multiple distinct associations	12
Induced pluripotent stem cell technology: trends in molecular biology, from genetics to epigenetics	12
HAR1: an insight into lncRNA genetic evolution	12
Dysregulation of schizophrenia-associated genes and genome-wide hypomethylation in neurons overexpressing DNMT1	11
Effects of microRNAs and long non-coding RNAs on chemotherapy response in glioma	11
Association of HERV-K and LINE-1 hypomethylation with reduced disease-free survival in melanoma patients	11
DNA methylation at the DMPK gene locus is associated with cognitive functions in myotonic dystrophy type 1	11
The relationship between epigenetics and microbiota in neuropsychiatric diseases	11
An integrative analysis identifying transcriptional features and key genes involved in COVID-19	11
Comprehensive analysis of epigenetic modifications and immune-cell infiltration in tissues from patients with systemic lupus erythematosus	11
The unfavorable clinical outcome of COVID-19 in smokers is mediated by H3K4me3, H3K9me3 and H3K27me3 histone marks	11
Characterization of epigenetic and transcriptional landscape in infantile hemangiomas with ATAC-seq and RNA-seq	11
Early pregnancy dyslipidemia is associated with placental DNA methylation at loci relevant for cardiometabolic diseases	11
Forced running exercise mitigates radiation-induced cognitive deficits via regulated DNA hydroxymethylation	10
Development and validation of an oxidative phosphorylation-related gene signature in lung adenocarcinoma	10
Molecular function predictions and diagnostic value analysis of plasma exosomal miRNAs in Hirschsprung’s disease	10
Epigenetic regulation of immune checkpoints and T cell exhaustion markers in tumor-infiltrating T cells of colorectal cancer patients	10
Sex- and tissue-specific effects of binge-level prenatal alcohol consumption on DNA methylation at birth	10
Aging-induced changes in sperm DNA methylation are modified by low dose of perinatal flame retardants	10
Impact of depression and stress on placental DNA methylation in ethnically diverse pregnant women	10
LncRNA Gas5 regulates Fn1 deposition via Creb5 in renal fibrosis	10
Alteration of the m6A methylation landscape in a mouse model of scleroderma	10
Novel insights toward human stroke-related epigenetics: circular RNA and its impact in poststroke processes	10
Changes ofBDNFexon IV DNA methylation are associated with methamphetamine dependence	10
Targeting SARS-CoV-2 using polycomb inhibitors as antiviral agents	10
Multi-omics analysis to identify driving factors in colorectal cancer	10
MiR-421 promotes lipid metabolism by targeting PTEN via activating PI3K/AKT/mTOR pathway in non-small cell lung cancer	10
Social determinants of late-life depression epigenetics	10
Expression profiles and functional analysis of plasma tRNA-derived small RNAs in children with fulminant myocarditis	10
H3K9 methyltransferase EHMT2/G9a controls ERVK-driven noncanonical imprinted genes	9
Analysis and annotation of DNA methylation in two nonhuman primate species using the Infinium Human Methylation 450K and EPIC BeadChips	9
Ubiquitination and SUMOylation: protein homeostasis control over cancer	9
DNA methylation in chronic obstructive pulmonary disease	9
The DNA methylation landscape of PD-1 (PDCD1) and adjacent lncRNA AC131097.3 in head and neck squamous cell carcinoma	9
External validation of integrated genetic-epigenetic biomarkers for predicting incident coronary heart disease	9
A preliminary analysis of LncRNA biomarkers for schizophrenia	9
Epi-drugs as triple-negative breast cancer treatment	9
Epigenomic programming in early fetal brain development	9
Single-cell epigenomics in cancer: charting a course to clinical impact	9
Hsa_circ_0001021 regulates intestinal epithelial barrier function via sponging miR-224-5p in ulcerative colitis	9
Roles of noncoding RNAs in the initiation and progression of myocardial ischemia–reperfusion injury	9
Differential expression of DNA methyltransferases and demethylases among the various testicular germ cell tumor subtypes	9
Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders	9
Statin therapy is associated with epigenetic modifications in individuals with Type 2 diabetes	9
Comprehensive epigenetic analysis of m6A modification in the hippocampal injury of diabetic rats	8
Knockdown of long noncoding RNA AC245100.4 inhibits the tumorigenesis of prostate cancer cells via the STAT3/NR4A3 axis	8
The placenta epigenome–brain axis: placental epigenomic and transcriptomic responses that preprogram cognitive impairment	8
NOL6 promotes the proliferation and migration of endometrial cancer cells by regulating TWIST1 expression	8
Implication of regulatory networks of long noncoding RNA/circular RNA-miRNA-mRNA in diabetic cardiovascular diseases	8
Polymorphisms of genes required for methionine synthesis and DNA methylation influence mitochondrial DNA methylation	8
Epigenetic-mediated N-methyl-D-aspartate receptor changes in the brain of isolated reared rats	8
Maternal anxiety and depression in pregnancy and DNA methylation of the NR3C1 glucocorticoid receptor gene	8
Circular RNA expression profiling and bioinformatic analysis of cumulus cells in endometriosis infertility patients	8
NEAT1 functions as a key mediator of BMP2 to promote osteogenic differentiation of renal interstitial fibroblasts	8
Altered expression of miR-142, miR-155, miR-499a and of their putative common target MDM2 in systemic lupus erythematosus	8
miRNA changes in the mouse placenta due to bisphenol A exposure	8
Identification of antisense lncRNAs targeting GSK3β as a regulator in major depressive disorder	8
Fusaric acid-induced epigenetic modulation of hepatic H3K9me3 triggers apoptosis in vitro and in vivo	8
Alterations in 5hmC level and genomic distribution in aging-related epigenetic drift in human adipose stem cells	8
Genome-wide associations between alcohol consumption and blood DNA methylation: evidence from twin study	8
Epigenomic effects of vitamin D in colorectal cancer	7
Leukocyte methylomic imprints of exposure to the genocide against the Tutsi in Rwanda: a pilot epigenome-wide analysis	7
LINC01133 hampers the development of gastric cancer through increasing somatostatin via binding to microRNA-576-5p	7
Racial and ethnic representation in epigenomic studies of preterm birth: a systematic review	7
Osteoblast-derived lipocalin-2 regulated by miRNA-96-5p/Foxo1 advances the progression of Alzheimer’s disease	7
DNA methylation markers for endometrial cancer detection in minimally invasive samples: a systematic review	7
miRNA 146b-5p protects against atherosclerosis by inhibiting vascular smooth muscle cell proliferation and migration	7
Dysregulated expression of miRNAs in immune thrombocytopenia	7
Methylation of N6-adenosine (m6A) modification in miRNAs and its implications in immunity	7
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer	7
DNA methylation episignatures: insight into copy number variation	7
The role of H3K9 acetylation and gene expression in different brain regions of Alzheimer’s disease patients	7
Hypoxia-associated alternative splicing signature in lung adenocarcinoma	7
RETRACTED: [Inhibition of CTCF-regulated miRNA-185-5p mitigates renal interstitial fibrosis of chronic kidney disease]	7
Epigenetic targeting of Waldenström macroglobulinemia cells with BET inhibitors synergizes with BCL2 or histone deacetylase inhibition	7
Neonatal necrotizing enterocolitis-associated DNA methylation signatures in the colon are evident in stool samples of affected individuals	7
Methylation of immune-regulatory cytokine genes and pancreatic cancer outcomes	7
Epigenetic fragility of the endocannabinoid system under stress: risk for mood disorders and pharmacogenomic implications	6
Telomere therapy for chronic kidney disease	6

MiRNA expression profiling in HIV pathogenesis, disease progression and response to treatment: a systematic review	6
TCONS_00483150 as a novel diagnostic biomarker of systemic lupus erythematosus	6
Influence of degree of DNA degradation in formalin-fixed and paraffin-embedded tissue samples on accuracy of genome-wide DNA methylation analysis	6
The bitter side of epigenetics: variability and resistance to chemotherapy	6
Epigenome-wide association scan identifies methylation sites associated with HIV infection	6
Genome-wide DNA methylation and RNA expression differences correlate with invasiveness in melanoma cell lines	6
LINE-1 hypomethylation is associated with poor risperidone response in a first episode of psychosis cohort	6
Potential epigenetic modifications implicated in triple- to quadruple-negative breast cancer transition: a review	6
Maternal lipodome across pregnancy is associated with the neonatal DNA methylome	6
Epigenetic signaling and crosstalk in regulation of gene expression and disease progression	6
Artificial neural networks reveal sex differences in gene methylation, and connections between maternal risk factors and symptom severity in autism spectrum disorder	6
Epigenetic axis of SNHG19/miR-137/TNFAIP1 modulates amyloid beta peptide 25–35-induced SH-SY5Y cytotoxicity	6
Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems	6
The landscape of histone modifications in epigenomics since 2020	6
SET protein modulates H4 histone methylation status and regulates miR-137 level in oral squamous cell carcinoma	6
DNA methylation changes and inflammaging in aging-associated diseases	6
The role of noncoding RNAs in pituitary adenoma	6
Possible roles of epigenetics in stem cell therapy for Parkinson’s disease	6
Comprehensive analysis of differentially expressed long noncoding RNAs, miRNAs and mRNAs in breast cancer brain metastasis	6
Epigenetic modifications of RNA and their implications in antiviral immunity	6
High serum miR-421 is associated with metabolic dysregulation and inflammation in patients with metabolic syndrome	5
Functional analysis of PCSK9 3′UTR variants and mRNA–miRNA interactions in patients with familial hypercholesterolemia	5
DNA methylation as the link between migration and the major noncommunicable diseases: the RODAM study	5
LncRNA H19 promotes tumor angiogenesis in smokers by targeting anti-angiogenic miRNAs	5
Comparative epigenome-wide analysis highlights placenta-specific differentially methylated regions	5
Differential RNA expression profiles and competing endogenous RNA-associated regulatory networks during the progression of atherosclerosis	5
Epigenetic association study uncovered H3K27 acetylation enhancers and dysregulated genes in high-fat-diet-induced nonalcoholic fatty liver disease in rats	5
CircRNA profiling identifies circRNF180 as a tumor suppressor in hepatocellular carcinoma	5
Bisubstrate inhibitors: the promise of a selective and potent chemical inhibition of epigenetic ‘writers’	5
Role of epigenetic drugs in sensitizing cancers to anticancer therapies: emerging trends and clinical advancements	5
Evaluating the challenges and reproducibility of studies investigating DNA methylation signatures of psychological stress	5
Human RNA-directed DNA methylation methylates high-mobility group box 1 protein-produced DNA gaps	5
Breast milk-derived extracellular vesicle miRNAs are associated with maternal asthma and atopy	5
Methylation quantitative trait locus analysis of chronic postsurgical pain uncovers epigenetic mediators of genetic risk	5
Correlation among maternal risk factors, gene methylation and disease severity in females with autism spectrum disorder	5
Nonsyndromic orofacial clefts in Chile: LINE-1 methylation and MTHFR variants	5
Identification of lncRNA-associated ceRNA network in high-grade serous ovarian cancer metastasis	5
The science of hope: an interview with Randy Jirtle	5
The relationship of childhood trauma and DNA methylation of NMDA receptor genes in first-episode schizophrenia	5
Cataloging recent advances in epigenetic alterations in major mental disorders and autism	5
Epigenome-wide association study of maternal hemoglobin A1c in pregnancy and cord blood DNA methylation	5
Complex cross-talk between EZH2 and miRNAs confers hallmark characteristics and shapes the tumor microenvironment	5
A perspective on diet, epigenetics and complex diseases: where is the field headed next?	5
Clinical value and potential mechanisms of LINC00221 in hepatocellular carcinoma based on integrated analysis	5
Perspectives on the use of super-enhancers as a defining feature of cell/tissue-identity genes	5
Exosome-derived ncRNAs as potential drivers of epigenetic reprogramming of cancer stem cells	5
circPlekha7 suppresses renal fibrosis via targeting miR-493-3p/KLF4	5
Distinct cytosine modification profiles define epithelial-to-mesenchymal cell-state transitions	4
How do sphingolipids play a role in epigenetic mechanisms and gene expression?	4
Association of grandmaternal smoking during pregnancy with DNA methylation of grandchildren: the Isle of Wight study	4
Leveraging the urban–rural divide for epigenetic research	4
Childhood exposure to hunger: associations with health outcomes in later life and epigenetic markers	4
Prognostic value of the miRNA-27a and PPAR/RXRα signaling axis in patients with thyroid carcinoma	4
Evaluation of DNA methylation in BDNF, SLC6A4, NR3C1 and FKBP5 before and after treatment with selective serotonin-reuptake inhibitor in major depressive disorder	4
Specific epigenetic age acceleration patterns among four molecular subtypes of gastric cancer and their prognostic value	4
Predictive significance of circulating histones in hepatocellular carcinoma patients treated with sorafenib	4
Differential long noncoding RNA profiling of BMI in twins	4
Biological functions of long noncoding RNAs and circular RNAs in small-cell lung cancer	4
A regulative epigenetic circuit supervised by HDAC7 represses IGFBP6 and IGFBP7 expression to sustain mammary stemness	4
Genetic variability in noncoding RNAs: involvement of miRNAs and long noncoding RNAs in osteoporosis pathogenesis	4
Identification of circular RNA expression profiles and potential biomarkers for intracerebral hemorrhage	4
Placental growth factor and Fms related tyrosine kinase-1 are hypomethylated in preeclampsia placentae	4
Deep characterization of paired chromatin and transcriptomes in four immune cell types from multiple sclerosis patients	4
Novel epigenetic link between gestational diabetes mellitus and macrosomia	4
Epigenetic age associates with psychosocial stress and resilience in children of Latinx immigrants	4
Novel free-circulating and extracellular vesicle-derived miRNAs dysregulated in Duchenne muscular dystrophy	4
The era of biomarkers and precision medicine in colorectal cancer: an interview with Ajay Goel	4
Mid-pregnancy maternal blood nitric oxide-related gene and miRNA expression are associated with preterm birth	4
(Epi)genetic regulation of osteopontin in colorectal cancerogenesis	4
Opioid medication use and blood DNA methylation: epigenome-wide association meta-analysis	4
The prognostic role of miR-31 in colorectal cancer: the results of a meta-analysis of 4720 patients	4
Cell-specific epigenetic drivers of pathogenesis in rheumatoid arthritis	4
Holistic insights into meningitic Escherichia coli infection of astrocytes based on whole transcriptome profiling	4
HDL-enriched miR-30a-5p is associated with HDL-cholesterol levels and glucose metabolism in healthy men and women	4
The diagnostic potential of the epigenome in autism spectrum disorders	4
DNMT3a promotes osteoblast differentiation and alleviates osteoporosis via the PPARγ/SCD1/GLUT1 axis	4
Comparison of DNA methylation clocks in Black South African men	4
New developments in non-exosomal and exosomal ncRNAs in coronary artery disease	4
Role of epigenetics in pancreatic ductal adenocarcinoma	4
Identification of CDC5L as bridge gene between chronic obstructive pulmonary disease and lung adenocarcinoma	4
Combination therapy and noncoding RNAs: a new era of cancer personalized medicine	4
Transcription factors: a potential therapeutic target in head and neck squamous cell carcinoma	4
DNA methylation differences in cortical grey and white matter in schizophrenia	4
Role of microRNAs and their involvement in preeclampsia	4
Genome-wide methylation analyses of human sperm unravel novel differentially methylated regions in asthenozoospermia	4
Epigenetics, environment and epidemiology: an interview with Karl Kelsey	4
Development and validation of the trans-omics model for pancreatic adenocarcinoma	3
Epigenetic signature of exposure to maternal Trypanosoma cruzi infection in cord blood cells from uninfected newborns	3
Maternal obesity is associated with a sex-specific epigenetic programming in human neonatal monocytes	3
Exosomal miRNAs in urine associated with children's cardiorenal parameters: a cross-sectional study	3
Apoptosis and myocardial infarction: role of ncRNAs and exosomal ncRNAs	3
A multi-omics approach to investigate the inflammatory response to life course socioeconomic position	3
Epigenetics and its therapeutic potential in colorectal cancer	3
CAVIN2 is frequently silenced by CpG methylation and sensitizes lung cancer cells to paclitaxel and 5-FU	3
Emerging functions and roles of circRNAs in cancer	3