Chinese Medicine

Article	Citations
Tea and tea drinking: China’s outstanding contributions to the mankind	120
Flavonoids on diabetic nephropathy: advances and therapeutic opportunities	65
Traditional application and modern pharmacological research of Eucommia ulmoides Oliv.	61
Propolis: An update on its chemistry and pharmacological applications	60
Network pharmacology based research into the effect and mechanism of Yinchenhao Decoction against Cholangiocarcinoma	59
Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer’s disease mice and glutamate-injured HT22 cells	59
Neurobiological effects of gallic acid: current perspectives	59
Pharmacological activities and mechanisms of action of Pogostemon cablin Benth: a review	55
Honokiol alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via Nrf2 activation in vitro and in vivo	55
Traditional Chinese Medicine for adjuvant treatment of breast cancer: Taohong Siwu Decoction	46
Plant metabolomics: a new strategy and tool for quality evaluation of Chinese medicinal materials	44
Traditional Chinese Medicine in nonalcoholic fatty liver disease: molecular insights and therapeutic perspectives	40
Advances in the study of emodin: an update on pharmacological properties and mechanistic basis	40
The mechanism of electroacupuncture for depression on basic research: a systematic review	40
Natural drug sources for respiratory diseases from Fritillaria: chemical and biological analyses	38
The toxicology and detoxification of Aconitum: traditional and modern views	38
Microwave technology: a novel approach to the transformation of natural metabolites	38
Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway	37
Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa	37
Efficacy and mechanisms of traditional Chinese medicine for COVID-19: a systematic review	37
Therapeutic potential of triptolide in autoimmune diseases and strategies to reduce its toxicity	36
Acupuncture for cancer pain: an evidence-based clinical practice guideline	34
Cucurbitacin B inhibits TGF-β1-induced epithelial–mesenchymal transition (EMT) in NSCLC through regulating ROS and PI3K/Akt/mTOR pathways	32
Oral colon-targeting core–shell microparticles loading curcumin for enhanced ulcerative colitis alleviating efficacy	32
Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury	32

Zoology, chemical composition, pharmacology, quality control and future perspective of Musk (Moschus): a review	31
Chaihu-Shugan-San (Shihosogansan) alleviates restraint stress-generated anxiety and depression in mice by regulating NF-κB-mediated BDNF expression through the modulation of gut microbiota	31
Plant super-barcode: a case study on genome-based identification for closely related species of Fritillaria	31
Combination of pseudoephedrine and emodin ameliorates LPS-induced acute lung injury by regulating macrophage M1/M2 polarization through the VIP/cAMP/PKA pathway	29
Mechanism of drug-induced liver injury and hepatoprotective effects of natural drugs	29
Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action	28
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment valida	28
CRISPR-Cas gene editing technology and its application prospect in medicinal plants	28
Therapeutic material basis and underling mechanisms of Shaoyao Decoction-exerted alleviation effects of colitis based on GPX4-regulated ferroptosis in epithelial cells	28
DNA barcoding: an efficient technology to authenticate plant species of traditional Chinese medicine and recent advances	27
The important herbal pair for the treatment of COVID-19 and its possible mechanisms	27
Psoralea corylifolia L.: a comprehensive review of its botany, traditional uses, phytochemistry, pharmacology, toxicology, quality control and pharmacokinetics	27
From natural dye to herbal medicine: a systematic review of chemical constituents, pharmacological effects and clinical applications of indigo naturalis	26
Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway	26
Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis	26
The role of macrophage polarization and associated mechanisms in regulating the anti-inflammatory action of acupuncture: a literature review and perspectives	26
Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression	25
Phytochemicals targeting Toll-like receptors 4 (TLR4) in inflammatory bowel disease	25
Chinese herbal medicines in the treatment of ulcerative colitis: a review	25
Traditional Chinese herbal medicine-potential therapeutic application for the treatment of COVID-19	25
The drug likeness analysis of anti-inflammatory clerodane diterpenoids	25
Pharmacological activities and molecular mechanisms of Pulsatilla saponins	24
Network pharmacology: a bright guiding light on the way to explore the personalized precise medication of traditional Chinese medicine	24
Current status of traditional Chinese medicine for the treatment of COVID-19 in China	24
Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells	23
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy	23
The emerging possibility of the use of geniposide in the treatment of cerebral diseases: a review	23
Anti-platelet aggregation of Panax notoginseng triol saponins by regulating GP1BA for ischemic stroke therapy	22
Transcription factor EB agonists from natural products for treating human diseases with impaired autophagy-lysosome pathway	22
Isoflavones daidzin and daidzein inhibit lipopolysaccharide-induced inflammation in RAW264.7 macrophages	21
Applying regulatory science in traditional chinese medicines for improving public safety and facilitating innovation in China: a scoping review and regulatory implications	21
In vitro anti‐bacterial activity and network pharmacology analysis of Sanguisorba officinalis L. against Helicobacter pylori infection	21
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo	21
Catechins from oolong tea improve uterine defects by inhibiting STAT3 signaling in polycystic ovary syndrome mice	20
Integrated analysis of the chemical-material basis and molecular mechanisms for the classic herbal formula of Lily Bulb and Rehmannia Decoction in alleviating depression	20
Efficacy and safety of traditional Chinese medicines for non-alcoholic fatty liver disease: a systematic literature review of randomized controlled trials	20
Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress	20
Systemic elucidation on the potential bioactive compounds and hypoglycemic mechanism of Polygonum multiflorum based on network pharmacology	20
Effects of ginsenoside Rb1 on second-degree burn wound healing and FGF-2/PDGF-BB/PDGFR-β pathway modulation	19
Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis	19
Research of insomnia on traditional Chinese medicine diagnosis and treatment based on machine learning	19
Medicinal and edible plants in the treatment of dyslipidemia: advances and prospects	19
The three syndromes and six Chinese patent medicine study during the recovery phase of COVID-19	18
Two methoxy derivatives of resveratrol, 3,3′,4,5′-tetramethoxy-trans-stilbene and 3,4′,5-trimethoxy-trans-stilbene, suppress lipopolysaccharide-induced inflammation through inactivation of MAPK and NF	18
Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment	18
Strategies for molecular authentication of herbal products: from experimental design to data analysis	18
Medicinal plants utilized in the management of epilepsy in Ethiopia: ethnobotany, pharmacology and phytochemistry	18
Improvement of intestinal flora: accompany with the antihypertensive effect of electroacupuncture on stage 1 hypertension	18
Determination of the protective effects of Hua‐Zhuo‐Jie‐Du in chronic atrophic gastritis by regulating intestinal microbiota and metabolites: combination of liquid chromatograph mass spectrometer meta	18
Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy	18

A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model	17
Persimmon leaf extract alleviates chronic social defeat stress-induced depressive-like behaviors by preventing dendritic spine loss via inhibition of serotonin reuptake in mice	17
Effects of Chinese medicine for COVID-19 rehabilitation: a multicenter observational study	17
Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages	17
A review of Chinese medicine for the treatment of psoriasis: principles, methods and analysis	17
Research progress on quality assurance of genuine Chinese medicinal in Sichuan	17
Modulation of steroidogenesis by Actaea racemosa and vitamin C combination, in letrozole induced polycystic ovarian syndrome rat model: promising activity without the risk of hepatic adverse effect	17
Quality assessment and Q-markers discovery of Tongsaimai tablet by integrating serum pharmacochemistry and network pharmacology for anti-atherosclerosis benefit	17
Buyang Huanwu Decoction protects against STZ-induced diabetic nephropathy by inhibiting TGF-β/Smad3 signaling-mediated renal fibrosis and inflammation	17
Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation	16
Towards a better understanding of Fagopyrum dibotrys: a systematic review	16
Traditional Chinese medicine promotes bone regeneration in bone tissue engineering	16
Panax ginseng C. A. Meyer as a potential therapeutic agent for organ fibrosis disease	16
From Xiaoke to diabetes mellitus: a review of the research progress in traditional Chinese medicine for diabetes mellitus treatment	16
Echinacoside exhibits antidepressant-like effects through AMPAR–Akt/ERK–mTOR pathway stimulation and BDNF expression in mice	16
Suan-Zao-Ren Decoction ameliorates synaptic plasticity through inhibition of the Aβ deposition and JAK2/STAT3 signaling pathway in AD model of APP/PS1 transgenic mice	16
A correlational study of Weifuchun and its clinical effect on intestinal flora in precancerous lesions of gastric cancer	16
Mineral medicine: from traditional drugs to multifunctional delivery systems	16
Therapeutic roles of natural remedies in combating hereditary ataxia: A systematic review	16
Honeysuckle-derived microRNA2911 inhibits tumor growth by targeting TGF-β1	16
Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancer	15
Beneficial effect of Indigo Naturalis on acute lung injury induced by influenza A virus	15
Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice	15
Artificial intelligence-directed acupuncture: a review	15
Corydalis saxicola Bunting total alkaloids attenuate paclitaxel-induced peripheral neuropathy through PKCε/p38 MAPK/TRPV1 signaling pathway	15
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation	15
Traditional chinese medicine syndromes classification associates with tumor cell and microenvironment heterogeneity in colorectal cancer: a single cell RNA sequencing analysis	15
Frontier progress of the combination of modern medicine and traditional Chinese medicine in the treatment of hepatocellular carcinoma	15
Global trends and prospects about inflammasomes in stroke: a bibliometric analysis	15
Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases	14
Comparison of the chemical constituents and anti-Alzheimer’s disease effects of Uncaria rhynchophylla and Uncaria tomentosa	14
Ginsenoside Rh2 represses autophagy to promote cervical cancer cell apoptosis during starvation	14
Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress	14
A review on the applications of Traditional Chinese medicine polysaccharides in drug delivery systems	14
Astragalus membranaceus (Huangqi) and Rhizoma curcumae (Ezhu) decoction suppresses colorectal cancer via downregulation of Wnt5/β-Catenin signal	14
Protective effects of Ginkgo Biloba Dropping Pills against liver ischemia/reperfusion injury in mice	14
New bakuchiol dimers from Psoraleae Fructus and their inhibitory activities on nitric oxide production	14
The influence of TCM constitutions and neurocognitive function in elderly Macau individuals	14
Schisandrin protects against ulcerative colitis by inhibiting the SGK1/NLRP3 signaling pathway and reshaping gut microbiota in mice	14
Alpinetin promotes hair regeneration via activating hair follicle stem cells	14
Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway	14
Chinese integrated guideline on the management of gastric precancerous conditions and lesions	13
Anti-malarial drug: the emerging role of artemisinin and its derivatives in liver disease treatment	13
Poria cocos polysaccharides exert prebiotic function to attenuate the adverse effects and improve the therapeutic outcome of 5-FU in ApcMin/+ mice	13
Adverse effects associated with acupuncture therapies: An evidence mapping from 535 systematic reviews	13
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy	13
Exploring the active components and potential mechanisms of Rosa roxburghii Tratt in treating type 2 diabetes mellitus based on UPLC-Q-exactive Orbitrap/MS and network pharmacology	13
Roles of reactive oxygen species, mitochondrial membrane potential, and p53 in evodiamine-induced apoptosis and G2/M arrest of human anaplastic thyroid carcinoma cells	13
Contents of lobetyolin, syringin, and atractylolide III in Codonopsis pilosula are related to dynamic changes of endophytes under drought stress	13
P2Y12 receptor as a new target for electroacupuncture relieving comorbidity of visceral pain and depression of inflammatory bowel disease	13
Integrating network pharmacology, UPLC-Q–TOF–MS and molecular docking to investigate the effect and mechanism of Chuanxiong Renshen decoction against Alzheimer's disease	13
The key issues and development strategy of Chinese Classical Formulas pharmaceutical preparations	13
Understanding the tonifying and the detoxifying properties of Chinese medicines from their impacts on gut microbiota and host metabolism: a case study with four medicinal herbs in experimental colitis	13
Scutellarin ameliorates neonatal hypoxic-ischemic encephalopathy associated with GAP43-dependent signaling pathway	13
Gut microbiota: a potential target for traditional Chinese medicine intervention in coronary heart disease	12
Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats	12
Effects of acupuncture at acupoints with lower versus higher pain threshold for knee osteoarthritis: a multicenter randomized controlled trial	12
Angong Niuhuang Wan reduces hemorrhagic transformation and mortality in ischemic stroke rats with delayed thrombolysis: involvement of peroxynitrite-mediated MMP-9 activation	12
Shikonin attenuates rheumatoid arthritis by targeting SOCS1/JAK/STAT signaling pathway of fibroblast like synoviocytes	12
The efficacy and safety of combined chinese herbal medicine and western medicine therapy for COVID-19: a systematic review and meta-analysis	12
A novel multidimensional strategy to evaluate Belamcanda chinensis (L) DC and Iris tectorum Maxim based on plant metabolomics, digital reference standard analyzer and biological activities evaluation	12
Combination of curcumin and piperine synergistically improves pain-like behaviors in mouse models of pain with no potential CNS side effects	12
α-Mangostin inhibits LPS-induced bone resorption by restricting osteoclastogenesis via NF-κB and MAPK signaling	12
Formation of a traditional Chinese medicine self-assembly nanostrategy and its application in cancer: a promising treatment	12
Integrating metabolomic data with machine learning approach for discovery of Q-markers from Jinqi Jiangtang preparation against type 2 diabetes	12
Cucurbitacin E inhibits cellular proliferation and induces apoptosis in melanoma by suppressing HSDL2 expression	12
Effects of steam on polysaccharides from Polygonatum cyrtonema based on saccharide mapping analysis and pharmacological activity assays	12
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway	12
Electroacupuncture reduces cold stress-induced pain through microglial inactivation and transient receptor potential V1 in mice	12
Effect of traditional chinese medicine (TCM) and its fermentation using Lactobacillus plantarum on ceftriaxone sodium-induced dysbacteriotic diarrhea in mice	12
Eryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications	12
Rubus chingii Hu. unripe fruits extract ameliorates carbon tetrachloride-induced liver fibrosis and improves the associated gut microbiota imbalance	11
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway	11
Inhibitory effect of Isatis tinctoria L. water extract on DNCB-induced atopic dermatitis in BALB/c mice and HaCaT cells	11
An alcohol extract prepared from the male flower of Eucommia ulmoides Oliv. promotes synoviocyte apoptosis and ameliorates bone destruction in rheumatoid arthritis	11
Developing an artificial intelligence method for screening hepatotoxic compounds in traditional Chinese medicine and Western medicine combination	11
Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies	11
Chinese herbal compound prescriptions combined with Chinese medicine powder based on traditional Chinese medicine syndrome differentiation for treatment of chronic atrophic gastritis with erosion: a m	11
Metabolomics and integrated network pharmacology analysis reveal SNKAF decoction suppresses cell proliferation and induced cell apoptisis in hepatocellular carcinoma via PI3K/Akt/P53/FoxO signaling ax	11
The application of mass spectrometry imaging in traditional Chinese medicine: a review	11

The study of neuroprotective effects and underlying mechanism of Naoshuantong capsule on ischemia stroke mice	11
A review on the effect of garlic on diabetes, BDNF, and VEGF as a potential treatment for diabetic retinopathy	11
West meets east: open up a dialogue on phytomedicine	11
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters	11
Study protocol: Traditional Chinese Medicine (TCM) syndrome differentiation for heart failure patients and its implication for long-term therapeutic outcomes of the Qiliqiangxin capsules	11
Shenzhi Jiannao formula ameliorates vascular dementia in vivo and in vitro by inhibition glutamate neurotoxicity via promoting clathrin-mediated endocytosis	11
The combination of UHPLC-HRMS and molecular networking improving discovery efficiency of chemical components in Chinese Classical Formula	11
Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism	11