Acta Physiologica

Article	Citations
Mitochondrial quality surveillance as a therapeutic target in myocardial infarction	98
Nicotine and vascular dysfunction	46
Diet‐induced maternal obesity impacts feto‐placental growth and induces sex‐specific alterations in placental morphology, mitochondrial bioenergetics, dynamics, lipid metabolism and oxidative stress i	41
Mechanisms of proton pump inhibitor‐induced hypomagnesemia	41
Aestivationmotifs explain hypertension and muscle mass loss in mice with psoriatic skin barrier defect	41
Adaptive physiological water conservation explains hypertension and muscle catabolism in experimental chronic renal failure	41
Neuromuscular recruitment strategies of the vastus lateralis according to sex	38
Factors mediating exercise‐induced organ crosstalk	34
Cognitive impairment in myocardial infarction and heart failure	33
Ether lipids, sphingolipids and toxic 1‐deoxyceramides as hallmarks for lean and obese type 2 diabetic patients	33
L‐lactate induces neurogenesis in the mouse ventricular‐subventricular zone via the lactate receptor HCA1	32
Dietary influences on the Dahl SS rat gut microbiota and its effects on salt‐sensitive hypertension and renal damage	32
Ectotherm mitochondrial economy and responses to global warming	31
Absence of neocytolysis in humans returning from a 3‐week high‐altitude sojourn	30
PACSIN proteins in vivo: Roles in development and physiology	29
Uterine contractions in rodent models and humans	28
EGCG inhibits pressure overload‐induced cardiac hypertrophy via the PSMB5/Nmnat2/SIRT6‐dependent signalling pathways	28
Pharmacological inhibition of USP30 activates tissue‐specific mitophagy	27
ENaC activation by proteases	27
Good publication practice in physiology 2021	27
Gestational diabesity and foetoplacental vascular dysfunction	27
Germ‐free mice are not protected against diet‐induced obesity and metabolic dysfunction	27
The regulation of gastric ghrelin secretion	25
Mechanisms linking hypertriglyceridemia to acute pancreatitis	25
Role of SLC4 and SLC26 solute carriers during oxidative stress	24

Impaired renal HCO3− secretion in CFTR deficient mice causes metabolic alkalosis during chronic base‐loading	23
EPO synthesis induced by HIF‐PHD inhibition is dependent on myofibroblast transdifferentiation and colocalizes with non‐injured nephron segments in murine kidney fibrosis	23
A high‐fat diet changes astrocytic metabolism to promote synaptic plasticity and behavior	22
Endogenous flux of nitric oxide: Citrulline is preferred to Arginine	22
Extracellular vesicles and microRNAs are altered in response to exercise, insulin sensitivity and overweight	22
Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides	22
15N‐labeled dietary nitrate supplementation increases human skeletal muscle nitrate concentration and improves muscle torque production	22
“Time window” effect of Yoda1‐evoked Piezo1 channel activity during mouse skeletal muscle differentiation	21
Protein O‐GlcNAcylation in the heart	20
WNT/β‐catenin pathway is a key regulator of cardiac function and energetic metabolism	20
Microbiota‐derived extracellular vesicles and metabolic syndrome	20
Microbial DNA enrichment promotes liver steatosis and fibrosis in the course of non‐alcoholic steatohepatitis	19
Zymogen‐locked mutant prostasin (Prss8) leads to incomplete proteolytic activation of the epithelial sodium channel (ENaC) and severely compromises triamterene tolerance in mice	19
Microglia‐leucocyte axis in cerebral ischaemia and inflammation in the developing brain	19
Regulation of heart rate in vertebrates during hypoxia: A comparative overview	19
Podocyte apoptosis in diabetic nephropathy by BASP1 activation of the p53 pathway via WT1	18
The effect of blood‐flow‐restricted interval training on lactate and H+ dynamics during dynamic exercise in man	18
Circadian clocks' interactions with oxygen sensing and signalling	17
Muscle endoplasmic reticulum stress in exercise	17
Methodological considerations in measuring specific force in human single skinned muscle fibres	17
Fate‐mapping of erythropoietin‐producing cells in mouse models of hypoxaemia and renal tissue remodelling reveals repeated recruitment and persistent functionality	17
Extreme duration exercise affects old and younger men differently	17
ACE2 function in the pancreatic islet: Implications for relationship between SARS‐CoV‐2 and diabetes	17
The key role of physical activity against the neuromuscular deterioration in patients with Parkinson's disease	17
Circadian rhythm disruption in critically ill patients	17
Prolonged QT intervals in mice with cardiomyocyte‐specific deficiency of the molecular clock	17
Acidosis‐induced activation of distal nephron principal cells triggers Gdf15 secretion and adaptive proliferation of intercalated cells	16
A novel K+‐dependent Na+ uptake mechanism during low pH exposure in adult zebrafish (Danio rerio): New tricks for old dogma	16
Chronodisruption by chronic jetlag impacts metabolic and gastrointestinal homeostasis in male mice	16
Pharmacological HIF‐PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation	16
Reversal of renal tissue hypoxia during experimental cardiopulmonary bypass in sheep by increased pump flow and arterial pressure	16
Glucose‐induced cAMP elevation in β‐cells involves amplification of constitutive and glucagon‐activated GLP‐1 receptor signalling	16
Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age‐dependent manner, normalizes GABA‐activated currents in the tg‐APPSwe mouse model of Alzheimer’s disease	16
Vesicular monoamine transporter 2 (SLC18A2) regulates monoamine turnover and brain development in zebrafish	16
Ribosome accumulation during early phase resistance training in humans	15
Neuromuscular fatigability at high altitude: Lowlanders with acute and chronic exposure, and native highlanders	15
The Na/K‐ATPase α1/Src interaction regulates metabolic reserve and Western diet intolerance	15
New insights into survival strategies to oxygen deprivation in anoxia‐tolerant vertebrates	15
Identification and functional analysis of two new de novo KCNMA1 variants associated with Liang–Wang syndrome	15
The role of the circadian clock in the development, progression, and treatment of non‐alcoholic fatty liver disease	15
Effects of parathyroid hormone on renal tubular calcium and phosphate handling	15
No functional TRPA1 in cardiomyocytes	15
Myonuclear content and domain size in small versus larger muscle fibres in response to 12 weeks of resistance exercise training in older adults	14
Local cyclic adenosine monophosphate signalling cascades—Roles and targets in chronic kidney disease	14
Dysfunction of circadian and sleep rhythms in the early stages of Alzheimer's disease	14
Influence of blood haemoglobin concentration on renal haemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep	14
Slow or fast: Implications of myofibre type and associated differences for manifestation of neuromuscular disorders	14
SARS‐CoV‐2 effects on the renin‐angiotensin‐aldosterone system, therapeutic implications	14
Obesogenic diet in mice compromises maternal metabolic physiology and lactation ability leading to reductions in neonatal viability	14
Oxytocin modulates neural processing of mitral/tufted cells in the olfactory bulb	14

Impact of paternal exercise on physiological systems in the offspring	14
Natriuretic peptides relax human intrarenal arteries through natriuretic peptide receptor type‐A recapitulated by soluble guanylyl cyclase agonists	14
Acute normobaric hypoxia blunts contraction‐mediated mTORC1‐ and JNK‐signaling in human skeletal muscle	14
The chromogranin A1‐373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin‐1	14
Clustering of desmosomal cadherins by desmoplakin is essential for cell‐cell adhesion	13
Chloride channel inhibition improves neuromuscular function under conditions mimicking neuromuscular disorders	13
Molecular physiology of Arc/Arg3.1: The oligomeric state hypothesis of synaptic plasticity	13
When should I eat: A circadian view on food intake and metabolic regulation	13
Ca2+ mishandling in heart failure: Potential targets	13
Enhanced phosphate absorption in intestinal epithelial cell‐specific NHE3 knockout mice	13
Transient increase in recurrent inhibition in amyotrophic lateral sclerosis as a putative protection from neurodegeneration	13
L‐carnitine alleviates cardiac microvascular dysfunction in diabetic cardiomyopathy by enhancing PINK1‐Parkin‐dependent mitophagy through the CPT1a‐PHB2‐PARL pathways	12
High‐intensity exercise in hypoxia improves endothelial function via increased nitric oxide bioavailability in C57BL/6 mice	12
Benefits of pharmacological and electrical cholinergic stimulation in hypertension and heart failure	12
Single cell‐ and spatial ‘Omics revolutionize physiology	12
Galectin‐3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling	12
Attenuation of inward rectifier potassium current contributes to the α1‐adrenergic receptor‐induced proarrhythmicity in the caval vein myocardium	12
ZFHX3 knockdown dysregulates mitochondrial adaptations to tachypacing in atrial myocytes through enhanced oxidative stress and calcium overload	12
Fifty years of the mitochondrial pyruvate carrier: New insights into its structure, function, and inhibition	12
MAFA and MAFB regulate exocytosis‐related genes in human β‐cells	12
A single dose of exercise stimulates skeletal muscle mitochondrial plasticity in myotonic dystrophy type 1	11
Uric acid transport, transporters, and their pharmacological targeting	11
Muscle‐tendon architecture in Kenyans and Japanese: Potential role of genetic endowment in the success of elite Kenyan endurance runners	11
Radial stem astrocytes (aka neural stem cells): Identity, development, physio‐pathology, and therapeutic potential	11
High phosphate impairs arterial endothelial function through AMPK‐related pathways in mouse resistance arteries	11
The effect of specific bioactive collagen peptides on function and muscle remodeling during human resistance training	11
Rodent models to study sodium retention in experimental nephrotic syndrome	11
Contextualizing the biological relevance of standardized high‐resolution respirometry to assess mitochondrial function in permeabilized human skeletal muscle	11
Mitochondria‐derived damage‐associated molecular patterns and inflammation in the ischemic‐reperfused heart	11
Subthalamic neurons interact with nigral dopaminergic neurons to regulate movement in mice	11
Calcineurin (PPP3CB) regulates angiotensin II‐dependent vascular remodelling by potentiating EGFR signalling in mice	11
Assessing mitochondrial respiration in permeabilized fibres and biomarkers for mitochondrial content in human skeletal muscle	10
Sleep and circadian rhythms in α‐synucleinopathies—Perspectives for disease modification	10
Sex differences in antiviral immunity in SARS‐CoV‐2 infection: Mitochondria and mitomiR come into view	10
Sestrin2 ablation attenuates the exercise‐induced browning of white adipose tissue in C57BL/6J mice	10
Intestinal mesenchymal cells regulate immune responses and promote epithelial regeneration in vitro and in dextran sulfate sodium‐induced experimental colitis in mice	10
Monitoring kidney size to interpret MRI‐based assessment of renal oxygenation in acute pathophysiological scenarios	10
The cold‐sensing ion channel TRPM8 regulates central and peripheral clockwork and the circadian oscillations of body temperature	10
Angiotensin II receptor blockade alleviates calcineurin inhibitor nephrotoxicity by restoring cyclooxygenase 2 expression in kidney cortex	10
The impact of macronutrient composition on metabolic regulation: An Islet‐Centric view	10
Did you know? Using entropy and fractal geometry to quantify fluctuations in physiological outputs	10
Functions of G protein‐coupled receptor 56 in health and disease	9
Post‐COVID‐19 neuropsychiatric syndrome: Is maladaptive glial recovery to blame?	9
Acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals	9
Catestatin induces glycogenesis by stimulating the phosphoinositide 3‐kinase‐AKT pathway	9
Platelets and endothelial dysfunction in gestational diabetes mellitus	9
The CaSR/TRPV4 coupling mediates pro‐inflammatory macrophage function	9
SARM1 promotes the neuroinflammation and demyelination through IGFBP2/NF‐κB pathway in experimental autoimmune encephalomyelitis mice	9
Neocytolysis on descending the mountain and ascending into space	9
Dining on the dead in the deep: Active NH4+ excretion via Na+/H+(NH4+) exchange in the highly ammonia tolerant P	9
Reliable kidney size determination by magnetic resonance imaging in pathophysiological settings	9
Acute pyelonephritis: Increased plasma membrane targeting of renal aquaporin‐2	9
Renal handling of nitrate in women and men with elevated blood pressure	9
Neuropeptides and neurohormones in immune, inflammatory and cellular responses to ultraviolet radiation	9
Mesangial cells regulate the single nephron GFR and preserve the integrity of the glomerular filtration barrier: An intravital multiphoton microscopy study	9
Brainstem noradrenergic neurons: Identifying a hub at the intersection of cognition, motility, and skeletal muscle regulation	8
Hydrokinetic pancreatic function and insulin secretion are moduled by Cl− uniporter Slc26a9 in mice	8
Decidual factors and vasoactive intestinal peptide guide monocytes to higher migration, efferocytosis and wound healing in term human pregnancy	8
Tissue‐specific effects of exercise as NAD+‐boosting strategy: Current knowledge and future perspectives	8
Cardiorespiratory alterations following intermittent photostimulation of RVLM C1 neurons: Implications for long‐term blood pressure, breathing and sleep regulation in freely moving rats	8
Getting it right matters! Covid‐19 pandemic analogies to everyday life in medical sciences	8
Sodium/hydrogen‐exchanger‐2 modulates colonocyte lineage differentiation	8
rhADAMTS13 reduces oxidative stress by cleaving VWF in ischaemia/reperfusion‐induced acute kidney injury	8
Ablation of microRNAs in VIP+ interneurons impairs olfactory discrimination and decreases neural activity in the olfactory bulb	8
ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischaemia/reperfusion injury	8
Endothelial cells promote smooth muscle cell resilience to H2O2‐induced cell death in mouse cerebral arteries	8
Macrophage activation in stellate ganglia contributes to lung injury‐induced arrhythmogenesis in male rats	8
TRPV3 and TRPV4 as candidate proteins for intestinal ammonium absorption	8
A critical role of the podocyte cytoskeleton in the pathogenesis of glomerular proteinuria and autoimmune podocytopathies	8
Regulation of heart rate following genetic deletion of the ß1 adrenergic receptor in larval zebrafish	8
Dietary K+ acts as a genuine diuretic	8
The genetic deletion of the Dual Specificity Phosphatase 3 (DUSP3) attenuates kidney damage and inflammation following ischaemia/reperfusion injury in mouse	8
Fifty years on: How we uncovered the unique bioenergetics of brown adipose tissue	8
Celebrities in the heart, strangers in the pancreatic beta cell: Voltage‐gated potassium channels Kv7.1 and Kv11.1 bridge long QT syndrome with hyperinsulinaemia as well as type	7
Extensive profiling of histidine‐containing dipeptides reveals species‐ and tissue‐specific distribution and metabolism in mice, rats, and humans	7
Does neocytolysis exist after descent from high altitude?	7
Muscle shape changes in Parkinson's disease impair function during rapid contractions	7
Pathophysiological mechanisms of reduced physical activity: Insights from the human step reduction model and animal analogues	7
Erythrocyte metabolism	7
Svante Pääbo, reader of the Neanderthal genome	7

The highly expressed calcium‐insensitive synaptotagmin‐11 and synaptotagmin‐13 modulate insulin secretion	7
MiR‐205 is up‐regulated in islets of diabetes‐susceptible mice and targets the diabetes gene Tcf7l2	7
When should I run—the role of exercise timing in metabolic health	7
Uremic toxins in chronic kidney disease highlight a fundamental gap in understanding their detrimental effects on cardiac electrophysiology and arrhythmogenesis	7
Heme oxygenase‐1 prevents non‐alcoholic steatohepatitis through modulating mitochondrial quality control	7
Reduce, replace, refine—Animal experiments	7
β2‐adrenergic stimulation potentiates spontaneous calcium release by increasing signal mass and co‐activation of ryanodine receptor clusters	7
mTORsignaling in renal ion transport	7
Exercise‐mediated autophagy in cardiovascular diseases	7
Rats lackingUcp1present a novel translational tool for the investigation of thermogenic adaptation during cold challenge	7
Multiple sclerosis and circadian rhythms: Can diet act as a treatment?	7
A five amino acids deletion in NKCC2 of C57BL/6 mice affects analysis of NKCC2 phosphorylation but does not impact kidney function	7
The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome	7
Cav3.1 t‐type calcium channel is critical for cell proliferation and survival in newly generated cells of the adult hippocampus	7
Cardiac sensory afferents modulate susceptibility to anxio‐depressive behaviour in a mouse model of chronic heart failure	7
Data integration and analysis for circadian medicine	7
Aerobic‐interval exercise with blood flow restriction potentiates early markers of metabolic health in man	7
Influence of moderate hypothermia on renal and cerebral haemodynamics and oxygenation during experimental cardiopulmonary bypass in sheep	6
Abnormal myosin post‐translational modifications and ATP turnover time associated with human congenital myopathy‐related RYR1 mutations	6
A juvenile climbing exercise establishes a muscle memory boosting the effects of exercise in adult rats	6
ID2 controls differentiation of enteroendocrine cells in mouse small intestine	6
Metabolic effects of L‐citrulline in type 2 diabetes	6
Inter‐individual variability in redox and performance responses after antioxidant supplementation: A randomized double blind crossover study	6
The effects of exercise intensity and duration on the relationship between the slow component of V̇O2 and peripheral fatigue	6
AKI and CKD	6
Carotid body responses to O2 and CO2 in hypoxia‐tolerant naked mole rats	6
EP1 receptor antagonism mitigates early and late stage renal fibrosis	6
Endothelial KCa1.1 and KCa3.1 channels mediate rat intrarenal artery endothelium‐derived hyperpolarization response	6
How to increase cellular oxygen availability in COVID‐19?	6
GDF15 mediates renal cell plasticity in response to potassium depletion in mice	6
Aquaporin 4 differentially modulates osmotic effects on vasopressin neurons in rat supraoptic nucleus	6
Significant significance?	6
Time‐restricted eating for chronodisruption‐related chronic diseases	6
1‐Deoxyceramides – Key players in lipotoxicity and progression to type 2 diabetes?	6
One step closer to myocardial physiology: From PV loop analysis to state‐of‐the‐art myocardial imaging	6
The adipose‐derived stem cell peptide ADSCP2 alleviates hypertrophic scar fibrosis via binding with pyruvate carboxylase and remodeling the metabolic landscape	6
Diet‐induced iron deficiency in rats impacts small intestinal calcium and phosphate absorption	6
Physical activity and sedentary behavior show distinct associations with tissue‐specific insulin sensitivity in adults with overweight	6
Accelerometer‐based sedentary time, light physical activity, and moderate‐to‐vigorous physical activity from childhood with arterial stiffness and carotid IMT progression: A	6
A bird’s eye view of the dynamics of pancreatic β‐cell heterogeneity	6
The regulatory mechanism between lysosomes and mitochondria in the aetiology of cardiovascular diseases	6
Pulmonary impairment in type 2 diabetic rats and its improvement by exercise	5
Drug metabolism in animal models and humans: Translational aspects and chances for individual therapy	5
Nuclei isolation methods fail to accurately assess the subcellular localization and behaviour of proteins in skeletal muscle	5
Costly immunometabolic remodelling in disused muscle buildup through physical exercise	5
Angiotensin‐converting enzyme inhibitors stimulate cerebral arteriogenesis	5
MFN2 deficiency promotes cardiac response to hypobaric hypoxia by reprogramming cardiomyocyte metabolism	5
Furosemide rescues hypercalciuria in familial hypomagnesaemia with hypercalciuria and nephrocalcinosis model	5
Activation of Kir4.1/Kir5.1 contributes to the cyclosporin A‐induced stimulation of the renal NaCl cotransporter and hyperkalemic hypertension	5
High‐phosphate diet causes atrial remodeling and increases atrial fibrillation vulnerability via STAT3/NF‐κB signaling and oxidative stress	5
HDAC3 inhibition improves urinary‐concentrating defect in hypokalaemia by promoting AQP2 transcription	5
Reduced glucose tolerance and insulin sensitivity after prolonged exercise in endurance athletes	5
Cells of the renin lineage promote kidney regeneration post‐release of ureteral obstruction in neonatal mice	5
Dynorphin promotes stress‐induced depressive behaviors by inhibiting ventral pallidal neurons in rats	5
Collecting duct renin regulates potassium homeostasis in mice	5
Endothelial cell plasticity in kidney fibrosis and disease	5
The role of the mesangium in glomerular function	5
Mitochondrial dysfunction in fatal ventricular arrhythmias	5
Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra‐coronary aortic banding	5
A new model for sodium uptake in the zebrafish gill	5
The absence of functional bassoon at cone photoreceptor ribbon synapses affects signal transmission at Off cone bipolar cell contacts in mouse retina	5
Muscle contraction and mitochondrial biogenesis – A brief historical reappraisal	5
Dichotomous effects on lymphatic transport with loss of caveolae in mice	5
Multiplex analysis of mass imaging data: Application to the pathology of experimental myocardial infarction	5
The effects of recruitment of renal functional reserve on renal cortical and medullary oxygenation in non‐anesthetized sheep	5
cAMP: A master regulator of cadherin‐mediated binding in endothelium, epithelium and myocardium	5
Strong ion difference: Inconsistencies lining up	5
Stewart's approach: Just a heresy or another lens into acid‐base physiology?	4
MFN2: Shaping mitochondria and cardiac adaptations to hypoxia	4
Tolerability safety and effectiveness of enhanced external counterpulsation versus individual shear rate therapy in patients with lower extremity atherosclerotic disease: A prospective pilot clinical	4
Tetrahydrobiopterin synthesis and metabolism is impaired in dystrophin‐deficient mdx mice and humans	4
Strong ion difference: Questionable stewardship	4
Targeting the mitochondrial Ca2+ uniporter complex in cardiovascular disease	4
The circadian neurobiology of reward	4
Glomerular microcirculation: Implications for diabetes, preeclampsia, and kidney injury	4
Neurovascular hypoxia after mild traumatic brain injury in juvenile mice correlates with heart–brain dysfunctions in adulthood	4
Lack of the transcription factor Nfix causes tachycardia in mice sinus node and rats neonatal cardiomyocytes	4
Hypertension due to loss of water	4
Estimating kidney function in patients with cancer: A narrative review	4
Time for circadian medicine	4
Citrullination is linked to reduced Ca2+ sensitivity in hearts of a murine model of rheumatoid arthritis	4
GLP‐1 modulates insulin‐induced relaxation response through β‐arrestin2 regulation in diabetic mice aortas	4
Complexity analysis from EEG data in congestive heart failure: A study via approximate entropy	4
Kv7 channel trafficking by the microtubule network in vascular smooth muscle	4
A further increase in Acta Physiologica’s impact factor	4
Neocytolysis after return from high altitude (5100 m): Further evidence for absentia	4
MFN2 overexpression in skeletal muscles of young and old mice causes a mild hypertrophy without altering mitochondrial respiration and H2O2 emission	4
Ventilatory responses to hypoxic and hypercapnic environments in naked mole‐rats	4
Computational cardiac physiology for new modelers: Origins, foundations, and future	4
Peripheral chemoreflex activation induces expiratory but not inspiratory excitation of C1 pre‐sympathetic neurones of rats	4
Exercise modifies fatty acid perception and metabolism	4
Exercise‐inducible circulating extracellular vesicle irisin promotes browning and the thermogenic program in white adipose tissue	4
Sex‐related differences in motor unit behavior are influenced by myosin heavy chain during high‐ but not moderate‐intensity contractions	4
A crucial physiological role of Piezo1 channel in differentiation rather than proliferation during myogenesis	4
HCN and nicotine	4