Chemical Biology & Drug Design

Article	Citations
Synthesis and antiviral activity of 2′‐deoxy‐6′‐substituted carbocyclic nucleosides	145
Design, synthesis, and biological evaluation of novel 4,4‐difluoro‐1‐methyl‐N, 6‐diphenyl‐5, 6‐dihydro‐4H‐pyrimido [4, 5‐b] [1, 2, 4] triazolo [4, 3‐d] [1, 4] diazepin‐8‐am	87
Diosgenin inhibits proliferation and migration of ovarian cancer cells and induce apoptosis via upregulation of PTEN	63
Role of Qufeng Tongqiao Prescription in the protection of cerebral ischemia and associated molecular network mechanism	55
Flubendazole suppresses VEGF‐induced angiogenesis in HUVECs and exerts antitumor effects in PC‐3 cells	46
Computational analysis followed by in vitro studies to explore cytokines (TNF‐α, IL‐6 and IL‐1β) inhibition potential of the new natural molecule polonilignan	44
Serum exosomal miR‐3662 down‐regulates the expression of RBMS3 to promote malignant progression and gemcitabine resistance of breast cancer cells	41
Design, synthesis, and anticancer evaluation of N6‐hydrazone purine derivatives with potential antiplatelet aggregation activity	40
Evaluation of the histamine H3 receptor antagonists from LINS01 series as cholinesterases inhibitors: Enzymatic and modeling studies	39
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Effect of novel therapeutic medicine swertiamarin from Enicostema axillare in zebrafish infected with Salmonella typhi	33
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In vitro effects of 2‐methyl‐3‐propylbutane‐1,4‐diol purified from Alstonia boonei on erythrocyte membrane stabilization and mitochondrial membrane permeabilization	32
HSYA prevents IL‐1β‐induced human chondrocyte damage in osteoarthritis by inhibiting NF‐κB activation	31
Synthesis and in vitro evaluation of antibacterial and antibiofilm activities of novel triphenylphosphonium‐functionalized substituted pyrimidines	31
Investigating the Role of Quercetin, an Active Ingredient in Bazhen Decoction, in Targeting CXCL8 to Inhibit Macrophage M2 Polarization and Reshape the Immunological Microenviron	30
Antimicrobial and Antiproliferative Properties of 2‐Phenyl‐N‐(Pyridin‐2‐yl)acetamides	29
Retraction Notice	27
Design, synthesis, in silico molecular docking, and ADMET studies of quinoxaline‐isoxazole‐piperazine conjugates as EGFR‐targeting agents	26
Ginkgetin alleviates high glucose‐evoked mesangial cell oxidative stress injury, inflammation, and extracellular matrix (ECM) deposition in an AMPK/mTOR‐mediated autophagy axis	25
Antiproliferative labdane diterpenes from the rhizomes of Hedychium flavescens Carey ex Roscoe	25
Review on marine sponge alkaloid, aaptamine: A potential antibacterial and anticancer drug	25
Design, synthesis, and antitumor activity evaluation of pretubulysin analogs	24
Bioisosteric modification on benzylidene‐carbonyl compounds improved the drug‐likeness and maintained the antifungal activity against Sporothrix brasiliensis	23

Medicarpin suppresses proliferation and triggeres apoptosis by upregulation of BID, BAX, CASP3, CASP8, and CYCS in glioblastoma	23
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Estrone analogs as potential inhibitors targeting EGFR‐MAPK pathway in non‐small‐cell lung cancer	22
Exploring the cell death mechanisms of cytotoxic [1,2,3]triazolylcarborane lead compounds against U87 MG human glioblastoma cells	22
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Systematic identification of activity cliffs with dual‐atom replacements and their rationalization on the basis of single‐atom replacement analogs and X‐ray structures	22
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Lack of efficacy of mono‐mode of action therapeutics in COVID‐19 therapy ‐ How the lack of predictive power of preclinical cell and animal studies leads developments astray	21
Neuroprotective potential of saroglitazar in 6‐OHDA induced Parkinson's disease in rats	19
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Radiosynthesis and in silico bioevaluation of 131I‐Sulfasalazine as a highly selective radiotracer for imaging of ulcerative colitis	19
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation	18
Piceatannol selectively inhibited the JNK3 enzyme and augmented apoptosis through inhibition of Bcl‐2/Cyt‐c/caspase‐dependent pathways in the oxygen–glucose deprived SHSY‐5Y cell lines: In silico and	18
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Discovery and evaluation of biphenyl derivatives of 2‐iminobenzimidazoles as prototype dual PTP1B inhibitors and AMPK activators with in vivo antidiabetic activity	18
Farnesoid X receptor represses human sulfotransferase 1A3 expression through direct binding to the promoter	18
Issue Information	17
Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease	17
A novel miRNA‐based signature as predictive tool of survival outcome of colorectal cancer patients	17
Application of kojic acid scaffold in the design of non‐tyrosinase enzyme inhibitors	17
Cyanidin as potential anticancer agent targeting various proliferative pathways	17
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Novel serratiopeptidase exhibits different affinities to the substrates and inhibitors	16
Puerarin Decreases the Expression of FUS‐Dependent MAPK4 to Inhibit the Development of Triple‐Negative Breast Cancer	16
Identification of 5‐(3‐(methylsulfonyl)phenyl)‐3‐(4‐(methylsulfonyl)phenyl)‐3H‐imidazo[4,5‐b]pyridine as novel orally bioavailable and metabolically stable antimalarial compou	15
Investigation on the antipyretic mechanism of Chaiqin Qingning capsule for the treatment of fever based on network pharmacology, molecular docking, and in vitro experimental validation	15
Elucidation of the mechanisms and molecular targets of KeChuanLiuWei‐Mixture for treatment of severe asthma based on network pharmacology	15
Punicalagin suppresses inflammation in ventilator‐induced lung injury through protease‐activated receptor‐2 inhibition‐induced inhibition of NLR family pyrin domain containing‐3 inflammasome activatio	15
Synthesis of N‐aminophalimides derived from α‐amino acids: Theoretical study to find them as HDAC8 inhibitors by docking simulations and in vitro assays	14
Chemical Biology and Drug Design: Introduction to the new Editor in Chief	14
Icariin alleviates the apoptosis of chondrocytes in osteoarthritis through regulating SIRT‐1‐Nrf2‐HO‐1 signaling	14
Heterocyclic and non‐heterocyclic arena of monocarboxylate transporter inhibitors to battle tumorigenesis	14
Folate trapping is lethal to cancer cells	14
Promotion Effect of Catalpol on Angiogenesis and Potential Mechanisms: A Research Based on Network Pharmacology	14
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Salviolone protects against high glucose‐induced proliferation, oxidative stress, inflammation, and fibrosis of human renal mesangial cells by upregulating membrane metalloendopeptidase expression	14
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Cytotoxic activity and cell specificity of a novel LHRH peptide drug conjugate, D‐Cys6‐LHRH vedotin, against ovarian cancer cell lines	14
O‐prenylated carbostyrils as a novel class of 15‐lipoxygenase inhibitors: Synthesis, characterization, and inhibitory assessment	14
Myoinositol and methyl stearate increases rifampicin susceptibility among drug‐resistant Mycobacterium tuberculosis expressing Rv1819c	13
Information‐theoretic approach in allometric scaling relations of DNA and proteins	13
Biological evaluation the 2‐aryl‐2,3‐dihydrobenzodiazaborinin‐4(1H)‐ones as potential dual α‐glucosidase and α‐amylase inhibitors with antioxidant properties	13
Delineating binding potential, stability of Sulforaphane‐N‐acetyl‐cysteine in the active site of histone deacetylase 2 and testing its cytotoxicity against distinct cancer lines through stringent mol	13
Ursolic and betulinic semisynthetic derivatives show activity against CQ‐resistant Plasmodium falciparum isolated from Amazonia	13
Computational prediction of Lee retention indices of polycyclic aromatic hydrocarbons by using machine learning	13
Elucidating specificity of an allosteric inhibitor WNK476 among With‐No‐Lysine kinase isoforms using molecular dynamic simulations	13
Structure‐based discovery of (S)‐2‐amino‐6‐(4‐fluorobenzyl)‐5,6,11,11a‐tetrahydro‐1H‐imidazo[1′,5′:1,6]pyrido[3,4‐b]indole‐1,3(2H)‐dione as low nanomolar, orally bioavailable autotaxin inhibito	13
Compounds from diverse natural origin against triple‐negative breast cancer: A comprehensive review	12

Synthesis and structure‐activity relationship of thiol‐based histone deacetylase 6 inhibitors	12
The utility of radiolabeled PSMA ligands for tumor imaging	12
Hsa‐miR‐503‐5p regulates CTDSPL to accelerate cisplatin resistance and angiogenesis of lung adenocarcinoma cells	12
Synthesis and antiviral activity of diverse heterocyclic scaffolds	12
SAR study of small molecule inhibitors of the programmed cell death‐1/programmed cell death‐ligand 1 interaction	12
Research progress on the P2X7 receptor in liver injury and hepatocellular carcinoma	12
Mollugin Derivatives as Anti‐Inflammatory Agents: Design, Synthesis, and NF‐κB Inhibition	11
Design, synthesis, and anticancer evaluation of alkynylated pyrrole derivatives	11
Recent progress of research on anti‐tumor agents using benzimidazole as the structure unit	11
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Peptide derived from plant defensins: A promising 68Ga radiolabelled agent for diagnostic of infection foci in PET	11
Synthesis and SAR investigation of biphenylaminoquinoline derivatives with benzyloxy substituents as promising anticancer agents	11
Lycorine Suppresses Non‐Small‐Cell Lung Cancer Progression Through Activating STING Pathway and Stimulating an Antitumor Immune Response	11
Synthesis, in vitro and in silico anti‐bacterial analysis of piperine and piperic ester analogues	11
Network pharmacology and experimental verification to explore the effect of Hedyotis diffusa on Alzheimer's disease	11
Novel phenylpiperazine derivatives as potent transient receptor potential vanilloid 1 antagonists	11
Tectorigenin Reduces Dabie bandavirus‐Induced Cytokine Storm by Regulating Toll‐Like Receptor 7/Extracellular Signal–Regulated Kinase Pathway	11
Novel Hydrazide‐Hydrazones Bearing a Benzimidazole Ring: Design, Synthesis, and Evaluation of Inhibitor Properties Against CA I and CA II Isozymes	11
Synthesis and anti‐SARS‐CoV‐2 activity of amino acid modified cephalotaxine derivatives	11
Fragment‐based in silico design of SARS‐CoV‐2 main protease inhibitors	11
Long noncoding RNA SNHG7‐miRNA‐mRNA axes crosstalk with oncogenic signaling pathways in human cancers	10
Alginate oligosaccharide alleviates senile osteoporosis via the RANKL–RANK pathway in D‐galactose‐induced C57BL/6J mice	10
Synthesis of new coumarin[1,3]oxazine derivatives of 7‐hydroxy‐6‐isobornyl‐4‐methylcoumarin and their antioxidant activity	10
The protective effect of karanjin against sepsis‐induced acute lung injury in mice is involved in the suppression of the TLR4 pathway	10
Hydroxamates as a potent skeleton for the development of metallo‐β‐lactamase inhibitors	10
The flavonoid Astragalin shows anti‐tumor activity and inhibits PI3K/AKT signaling in gastric cancer	10
Integrative analysis of ex vivo studies and microarray reveals the novel inhibitor effects of trehalose on the pathogenesis of pterygium	10
Evaluation of small molecule kinase inhibitors as novel antimicrobial and antibiofilm agents	10
99mTc‐labeled antibiotics for infection diagnosis: Mechanism, action, and progress	10
Protective effect of naringin against radiation‐induced heart disease in rats via Sirt1/NF‐κB signaling pathway and endoplasmic reticulum stress	9
Study on the molecular mechanism of dihydromyricetin in alleviating liver cirrhosis based on network pharmacology	9
Two new compounds from endemic Centaurea paphlagonica (Bornm.) Wagenitz and their cytotoxic activities	9
Berberine attenuates cognitive dysfunction and hippocampal apoptosis in rats with prediabetes	9
Exendin‐4: A potential therapeutic strategy for Alzheimer's disease and Parkinson's disease	9
Mechanisms analysis for Formononetin counteracted‐Osimertinib resistance in non‐small cell lung cancer cells: From the insight into the gene transcriptional level	9
Propofol inhibits the proliferation, invasion, migration, and angiogenesis of oral squamous cell carcinoma through circ_0008898‐mediated pathway	9
A comprehensive review on potential candidates for the treatment of chagas disease	9
Discussion on structure classification and regulation function of histone deacetylase and their inhibitor	9
Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking	9
Amentoflavone attenuates cell proliferation and induces ferroptosis in human gastric cancer by miR‐496/ATF2 axis	8
A novel link between melatonin and circ_0005753/PTBP1/TXNIP regulatory network in the modulation of osteogenic potential in mesenchymal stem cells	8
Combination of Diosmetin With Chrysin Against Hepatocellular Carcinoma Through Inhibiting PI3K/AKT/mTOR/NF‐кB Signaling Pathway: TCGA	8
Recent advances in antifungal drug development targeting lanosterol 14α‐demethylase (CYP51): A comprehensive review with structural and molecular insights	8
Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway	8
An improved synthesis of indanocine and antiproliferative activity of 2‐benzylindanocine via microtubule destabilization	8
Synthesis and anti‐inflammatory activity of novel firocoxib analogues with balanced COX inhibition	8
Ethyl gallate concurrent administration protects against acetaminophen‐induced acute liver injury in mice: An in vivo and in silico approach	8
Green synthesis and characterization of Solanum xanthocarpum capped silver nanoparticles and its antimicrobial effect on multidrug‐resistant bacterial (MDR) isolates	8
Specific delivering of RNAi using Spike's aptamer‐functionalized lipid nanoparticles for targeting SARS‐CoV‐2: A strong anti‐Covid drug in a clinical case study	8
In silico studies on recreational drugs: 3D quantitative structure activity relationship prediction of classified and de novo designer benzodiazepines	8
3‐O‐trans‐caffeoyloleanolic acid improves acute lung injury via anti‐inflammation and antioxidative stress‐involved PI3K/AKT pathway	8
HIV‐1 Gag MA domain binds to cardiolipin in a binding mode distinct from virus assemble mediator PI(4,5)P2	8
Metadherin inhibits chemosensitivity of triple‐negative breast cancer to paclitaxel via activation of AKT/GSK‐3β signaling pathway	8
Discovery of small molecule c‐Maf inhibitors using molecular docking‐based virtual screening, molecular dynamics simulation, and biological evaluation	8
Preparation and antioxidant activity of phosphorylated polysaccharide from purple sweet potato	8
Synthesis and evaluation of diphyllin β‐hydroxyl amino derivatives as novel V‐ATPase inhibitors	8
Analysis of bioactive compounds using LC–ESI–MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium	7
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Synthetic heterocyclic derivatives as promising xanthine oxidase inhibitors: An overview	7
Magnetic chitosan oligomer‐sulfonate‐stearic acid triple combination as cisplatin carrier for site‐specific targeted on MCF‐7 cancer cells: Preparation, characterization and in vitro experi	7
Caspase‐3: A primary target for natural and synthetic compounds for cancer therapy	7
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Correction to Silencing PCMT1 enhances the sensitivity of breast cancer cells to paclitaxel through the PI3K/Akt/STMN1 pathway	7
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Synergistic interaction of N‐3‐Br‐benzyl‐noscapine and docetaxel abrogates oncogenic potential of breast cancer cells	7
Extraction, derivatization, and antioxidant activity of Morinda citrifolia polysaccharide	7
Purification and structural analysis of a novel polysaccharide from Rehmannia Radix Praeparata	7
Correction to Analysis of bioactive compounds using LC–ESI–MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifoliu	7
A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease	7
Correction to “Naringin acts as a TRPV1 antagonist to attenuate UVB‐induced senescence and damage in HaCaT cells”	7
Exploration of the Active Components and Mechanism of Jiegeng (Platycodonis Radix) in the Treatment of Influenza Virus Pneumonia Through Network Pharmacology Analysis and Experimental Ve	7
Thymoquinone potentiates anti‐cancer effects of cisplatin in oral squamous cell carcinoma via targeting oxidative stress	7
Emerging quinoline‐ and quinolone‐based antibiotics in the light of epidemics	7
Pyrazolopyridine: An efficient pharmacophore in recent drug design and development	7
Design and Synthesis of 1,4‐Diformyl‐Piperazine Ferrostatin‐1 Derivatives as Novel Ferroptosis Inhibitors	7
Capsaicin derivatives: Synthesis and biological activity	6
Synthesis, biological evaluation and mechanism of action of benzothiazole derivatives with aromatic hydrazone moiety, a new class of antileishmanial compounds	6
A recent update on huprine and its hybrids as a potential multifunctional agent for the treatment of Alzheimer's disease	6
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Synthesis, cytotoxicity, and antibacterial studies of 2,4,5,6‐substituted hexahydro‐1H‐isoindole‐1,3(2H)‐dione	6

Design, synthesis, and primary activity assays of baicalein derivatives as cyclin‐dependent kinase 1 inhibitors	6
Development and characterization of two novel 68Ga‐labelled neuropeptide Y short analogues with potential application in breast cancer imaging	6
Discovering novel derivatives of STAT3 and HDAC inhibitors with anti‐tumor activity	6
Network pharmacology analysis and experimental evaluations of YH complex on androgenetic alopecia by regulating the androgenic‐apoptotic axis	6
TMEM97 knockdown inhibits 5‐fluorouracil resistance by regulating epithelial‐mesenchymal transition and ABC transporter expression via inactivating the Akt/mTOR pathwa	6
Glycyrrhetinic acid alleviates atrial fibrillation by inhibiting the expression of PIM1	6
Synthesis and cytotoxic evaluation of heterocyclic compounds by vinylic substitution of ketene dithioacetals	6
Asiatic acid inhibits rheumatoid arthritis fibroblast‐like synoviocyte growth through the Nrf2/HO‐1/NF‐κB signaling pathway	6
Exploring the binding mode of PQ912 against secretory glutaminyl cyclase through systematic exploitation of conformational ensembles	6
Leveraging binding pose metadynamics to optimise target fishing predictions for three diverse ligands and their true targets	6
Investigating potential mechanisms of vitamin D against thyroid cancer via network pharmacology and experimental validation	6
Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin‐2‐one moiety of phenyl 4‐(2‐oxoimidazolidin‐1‐yl)benzenesulfonates	6
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In silico optimization of analogs derived pro‐adrenomedullin peptide to evaluate antimicrobial potential	6
Identification of Fangji Huangqi Tang as a potential herbal formula for Sjogren syndrome treatment via network pharmacology and experimental validation	6
Discovery of novel inhibitors of CDK2 using docking and physics‐based binding free energy calculation	6
Transition metal complexes of hydrazones as potential antimicrobial and anticancer agents: A short review	6
Miltirone suppresses ESCC cell viability and invasion by promoting E3 ligase mediated‐FZD2 ubiquitination and degradation	6
Integration of NMR studies, computational predictions, and in vitro assays in the search of marine diterpenes with antitumor activity	6
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In silico identification and in vitro evaluation of a protein‐protein interaction inhibitor of Escherichia coli fatty acid biosynthesis	5
Quercetin inhibits breast cancer cell proliferation and survival by targeting Akt/mTOR/PTEN signaling pathway	5
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Therapeutic voyage of synthetic and natural xanthine oxidase inhibitors	5
Design, synthesis, and biological evaluation of tetrahydroisoquinoline stilbene derivatives as potential antitumor candidates	5
Quinoline‐based heterocyclic hydrazones: Design, synthesis, anti‐plasmodial assessment, and mechanistic insights	5
Friedlӓnder's synthesis of quinolines as a pivotal step in the development of bioactive heterocyclic derivatives in the current era of medicinal chemistry	5
Design and synthesis of novel 1,2,3,4‐tetrazines as new anti‐leukemia cancer agents	5
Design, synthesis, and biological evaluation of novel quinoxaline aryl ethers as anticancer agents	5
Sulfonyl thiourea derivatives from 2‐aminodiarylpyrimidines: In vitro and in silico evaluation as potential carbonic anhydrase I, II, IX, and XII inhibitors	5
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Temporal Lobe Epilepsy: What do we understand about protein alterations?	5
Development of potent inhibitors by fragment‐linking strategies	5
Design and synthesis of Fsp3‐enriched spirocyclic‐substituted diarylpyrimidine derivatives as novel HIV‐1 NNRTIs	5
Epigallocatechin‐3‐O‐gallate ameliorates oxidative stress‐induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway	5
On the use of electronegativity and electron affinity based pseudo‐molecular field descriptors in developing correlations for quantitative structure‐activity relationship modeling of drug activities	5
Protective effect of a mitochondria‐targeting peptide against paclitaxel‐induced peripheral neuropathy	5
C2‐linked alkynyl poly‐ethylene glycol(PEG) adenosine conjugates as water‐soluble adenosine receptor agonists	5
Ginsenoside Rg3 alleviates the migration, invasion, and angiogenesis of lung cancer cells by inhibiting the expressions of cyclooxygenase‐2 and vascular endothelial growth factor	5
Prediction of bioactivities of microsomal prostaglandin E2 synthase‐1 inhibitors by machine learning algorithms	5
Kaempferol attenuates inflammation in lipopolysaccharide‐induced gallbladder epithelial cells by inhibiting the MAPK/NF‐κB signaling pathway	5
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Synthesis of ring opening of evodiamine derivatives and evaluation on their biological activity	5
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Discovery of novel SecA inhibitors against “Candidatus Liberibacter asiaticus” through virtual screening and biological evaluation	5
Antibiotic–cell‐penetrating peptide conjugates targeting challenging drug‐resistant and intracellular pathogenic bacteria	5
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Design, synthesis, and modelling study of new 1,2,3‐triazole/chalcone hybrids with antiproliferative action as epidermal growth factor receptor inhibitors	5
Correction to “Nanoemulsion Based Lipid Nanoparticles for Effective Demethylcantharidin Delivery to Cure Liver Cancer”	5
Glaucocalyxin A attenuates carbon tetrachloride‐induced liver fibrosis and improves the associated gut microbiota imbalance	5
Brucine alleviates fibroblast‐like synoviocytes dysfunction and inflammation by regulating YY1 during rheumatoid arthritis	5
Paclitaxel may inhibit migration and invasion of gastric cancer cells via nod‐like receptor family pyrin domain‐containing 3/caspase‐1/Gasdermin E mediated pyroptosis pathway	4
Designing of kinase hinge binders: A medicinal chemistry perspective	4
Dietary Natural Flavonoids: Intervention for MAO‐B Against Parkinson's Disease	4
Development and radiosterilization of new hydrazono‐quinoline hybrids as DNA gyrase and topoisomerase IV inhibitors: Antimicrobial and hemolytic activities against uropathogenic	4
Nutraceutical combination ameliorates imiquimod‐induced psoriasis in mice	4
Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug‐carrier molecule for the treatment of glioblastoma	4
Discovery of novel antibacterial agents: Recent developments in D‐alanyl‐D‐alanine ligase inhibitors	4
Glycyrrhizic acid inhibits DNA damage repair and enhances cisplatin‐induced apoptosis of melanoma cells	4
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Upregulation of miR‐144‐3p alleviates Doxorubicin‐induced heart failure and cardiomyocytes apoptosis via SOCS2/PI3K/AKT axis	4
One‐Step Organic Synthesis of 18β‐Glycyrrhetinic Acid‐Anthraquinone Ester Products: Exploration of Antibacterial Activity and Structure–Activity Relationship, Toxicity Evaluation in Zebrafish	4
A highly bioavailable curcumin formulation ameliorates inflammation cytokines and neurotrophic factors in mice with traumatic brain injury	4
Extraction, chemical modification, and antioxidant activities of Daucus carota polysaccharide	4
Anti‐metastatic Effects of Bee Venom and Melittin in Breast Cancer Cells by Upregulation of BRMS1 and DRG1 Genes	4
Comprehensive Analysis of NADH:Ubiquinone Oxidoreductase Subunit B3 in Gynecological Tumors and Identification of Its Natural Inhibitor Wedelolactone	4
HIV‐1 integrase inhibitor raltegravir promotes DNA damage‐induced apoptosis in multiple myeloma	4
Synthesis and Preliminary Anticancer Evaluation of 4‐C Derivatives of Diphyllin	4
Molecular target interactions of quinoline derivatives as anticancer agents: A review	4
Hybrid PABA‐glutamic acid conjugated 1,3,5‐triazine derivatives: Design, synthesis, and antimalarial activity screening targeting Plasmodium falciparum dihydro folate reductase enzym	4
Sinomenine attenuates lipopolysaccharide‐induced inflammation and apoptosis of WI‐38 cells by reducing glutathione S‐transferase M1 expression	4
A new insight into the treatment of diabetes by means of pan PPAR agonists	4
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IKKα kinase silencing increases doxorubicin‐induced apoptosis through regulation of oxidative DNA damage response in colon cancer cells	4
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Synthesis and antiglycation activity of 3‐phenacyl substituted thiazolium salts, new analogs of Alagebrium	4
A newly synthesized thiosemicarbazide derivative trigger apoptosis rather than necroptosis on HEPG2 cell line	4
In silico prediction of boiling point, octanol–water partition coefficient, and retention time index of polycyclic aromatic hydrocarbons through machine learning	4
Comment on “Integrative Analysis of Ex Vivo Studies and Microarray Reveals the Novel Inhibitor Effects of Trehalose on the Pathogenesis of Pterygium”	4
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Identification of therapeutic miRNAs from the arsenic induced gene expression profile of hepatocellular carcinoma	4
N‐methylpiperazinyl and piperdinylalkyl‐O‐chalcone derivatives as potential polyfunctional agents against Alzheimer's disease: Design, synthesis and biological evaluation	4
Inhibition of BACE1 and amyloid β aggregation by polyketide from Streptomyces sp.	4
Design, synthesis, and biological evaluation of novel ruxolitinib and baricitinib analogues for potential use against COVID‐19	4
Exploration of potential inhibitors for autophagy‐related protein 8 as antileishmanial agents	4
4‐Quinolinylhydrazone analogues kill Leishmania (Leishmania) amazonensis by inducing apoptosis and mitochondria‐dependent pathway cell death	4
Synthesis and evaluation of di‐heterocyclic benzazole compounds as potential antibacterial and anti‐biofilm agents against Staphylococcus aureus	4
Why are heterocycles so special in medicinal chemistry?	4
Design, synthesis, and biological activity evaluation of new tankyrase‐2 directed inhibitors	4
BSV163/DOPE‐mediated TRAIL gene transfection acts synergistically with chemotherapy against cisplatin‐resistant ovarian cancer	4
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