Chemical Biology & Drug Design

Article	Citations
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Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development	65
Discovery of small molecule c‐Maf inhibitors using molecular docking‐based virtual screening, molecular dynamics simulation, and biological evaluation	58
Potential Modulatory Effects of Hesperidin on the JAK/STAT Pathway in Mesangial Proliferative Glomerulonephritis	58
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation	53
A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease	49
Discussion on structure classification and regulation function of histone deacetylase and their inhibitor	48
Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway	47
Effect of novel therapeutic medicine swertiamarin from Enicostema axillare in zebrafish infected with Salmonella typhi	42
Folate trapping is lethal to cancer cells	41
Computationally Driven Exploration of Novel bis‐Thiadiazole Sulfonamides as Alzheimer's Enzyme Inhibitors: A DFT and Kinetic Perspective	41
Estrone analogs as potential inhibitors targeting EGFR‐MAPK pathway in non‐small‐cell lung cancer	41
Correction to Silencing PCMT1 enhances the sensitivity of breast cancer cells to paclitaxel through the PI3K/Akt/STMN1 pathway	41
Investigating the Role of Quercetin, an Active Ingredient in Bazhen Decoction, in Targeting CXCL8 to Inhibit Macrophage M2 Polarization and Reshape the Immunological Microenviron	39
Two new compounds from endemic Centaurea paphlagonica (Bornm.) Wagenitz and their cytotoxic activities	38
Issue Information	35
Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease	35
Purification and structural analysis of a novel polysaccharide from Rehmannia Radix Praeparata	35
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C2‐linked alkynyl poly‐ethylene glycol(PEG) adenosine conjugates as water‐soluble adenosine receptor agonists	31
Exploration of potential inhibitors for autophagy‐related protein 8 as antileishmanial agents	31
Paclitaxel may inhibit migration and invasion of gastric cancer cells via nod‐like receptor family pyrin domain‐containing 3/caspase‐1/Gasdermin E mediated pyroptosis pathway	30
The Molecular Mechanism of Resveratrol in the Treatment of Chronic Rhinosinusitis Through a Combination of Network Pharmacology and In Vitro Validation	30
Hybrid PABA‐glutamic acid conjugated 1,3,5‐triazine derivatives: Design, synthesis, and antimalarial activity screening targeting Plasmodium falciparum dihydro folate reductase enzym	30

Investigating potential mechanisms of vitamin D against thyroid cancer via network pharmacology and experimental validation	29
Machine Learning‐Based Discovery of a Novel Noncovalent MurA Inhibitor as an Antibacterial Agent	29
BSV163/DOPE‐mediated TRAIL gene transfection acts synergistically with chemotherapy against cisplatin‐resistant ovarian cancer	28
TMEM97 knockdown inhibits 5‐fluorouracil resistance by regulating epithelial‐mesenchymal transition and ABC transporter expression via inactivating the Akt/mTOR pathwa	28
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Orthogonal threading‐through‐β‐sheet design of lung cancer EGFR extracellular domain‐derived peptidic mimotopes binding to anti‐EGFR antibody	26
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In silico prediction of boiling point, octanol–water partition coefficient, and retention time index of polycyclic aromatic hydrocarbons through machine learning	25
Corrigendum	25
Dietary Natural Flavonoids: Intervention for MAO‐B Against Parkinson's Disease	25
A recent update on huprine and its hybrids as a potential multifunctional agent for the treatment of Alzheimer's disease	25
miRNAs as key modulators between normal cells and tumor microenvironment interactions	24
A Naturally Derived Glycosylated Oleanolic Acid Derivative Suppresses NF‐κB Translocation and Induces Intrinsic Apoptosis in Lung Adenocarcinoma Cells	23
Novel Phenoxyacetic Acid (4‐Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site	23
Glycyrrhizic acid inhibits DNA damage repair and enhances cisplatin‐induced apoptosis of melanoma cells	22
Network pharmacology analysis and experimental evaluations of YH complex on androgenetic alopecia by regulating the androgenic‐apoptotic axis	22
Why are heterocycles so special in medicinal chemistry?	22
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Tetrazole: A privileged scaffold for the discovery of anticancer agents	21
Synthesis and evaluation of di‐heterocyclic benzazole compounds as potential antibacterial and anti‐biofilm agents against Staphylococcus aureus	21
Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug‐carrier molecule for the treatment of glioblastoma	21
Friedlӓnder's synthesis of quinolines as a pivotal step in the development of bioactive heterocyclic derivatives in the current era of medicinal chemistry	21
Design, synthesis and characterization of ethyl 3‐benzoyl‐7‐morpholinoindolizine‐1‐carboxylate as anti‐tubercular agents: In silico screening for possible target identification	21
Chemistry and biological evaluation of pyrido[4,3‐d]pyrimidines: A review	18
Small Molecule Inhibitors Targeting Cdc2‐Like Kinase 4: Advances, Challenges, and Opportunities	18
Integrated bioinformatics analysis reveals the bidirectional effects of TSPAN6 for cisplatin resistance in lung cancer	18
Antitumor and antioxidant activities of polysaccharides from the seaweed Durvillaea antarctica	18
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Progress of SARS‐CoV‐2 Main protease peptide‐like inhibitors	18
Methyl benzoate and cinnamate analogs as modulators of DNA methylation in hepatocellular carcinoma	18
Issue Information	18
Dexmedetomidine attenuates myocardial ischemia–reperfusion injury in hyperlipidemic rats by inhibiting inflammation, oxidative stress and NF‐κB	17
Synthesis and anti‐tumor activity evaluation of 1H‐pyrrolo[2,3‐b]pyridine‐2‐carboxamide derivatives with phenyl sulfonamide groups as potent RSK2 inhibitors	17
Design, synthesis, in vitro evaluation, and molecular modeling studies of N‐substituted benzomorphans, analogs of LP2, as novel MOR ligands	17
δ‐Tocotrienol Potentiates Breast and Prostate Cancer Cells to Paclitaxel via Suppressing PD‐L1‐Mediated Cancer‐Promoting Signaling	16
Glabridin inhibits urothelial bladder carcinoma cell growth in vitro and in vivo by inducing cell apoptosis and cell cycle arrest	16
Exploring the Artificial Intelligence and Its Impact in Pharmaceutical Sciences: Insights Toward the Horizons Where Technology Meets Tradition	16
Kisspeptin‐10 Improves Gestational Diabetes Mellitus Symptoms in Rats by Suppressing Insulin Resistance in Placental Trophoblast Cells by Activating the Cyclic AMP/Protein Kinase A Pathway	16
In vitro effects of thirty‐eight cardiac drugs on human serum paraoxonase	16
Exploring the interactive mechanism of acarbose with the amylase SusG in the starch utilization system of the human gut symbiont Bacteroides thetaiotaomicron through molecular modeli	15
In vitro cytotoxicity and docking study of novel symmetric and asymmetric dihydropyridines and pyridines as EGFR tyrosine kinase inhibitors	15
The designation, synthesis, and affinity determination of affinity peptide for anthrax protective antigen	15
Predicting clinical trial outcomes using drug bioactivities through graph database integration and machine learning	15
2, 4, 5‐Trideoxyhexopyranosides derivatives of diphyllin: Synthesis and anticancer activity	15
An appraisal on synthetic and pharmaceutical perspectives of quinoxaline 1,4‐di‐N‐oxide scaffold	14
Praeruptorin A inhibits the activation of NF‐κB pathway and the expressions of inflammatory factors in poly (I:C)‐induced RAW264.7 cells	14
Curcumin activates the JNK signaling pathway to promote ferroptosis in colon cancer cells	14
Plumbagin Triggers STING Pathway Activation to Suppress Non‐Small Cell Lung Cancer Progression	14

Sulfonated non‐saccharide molecules and human factor XIa: Enzyme inhibition and computational studies	14
Quercetin Prevents Hyperuricemia Associated With Gouty Arthritis by Inactivating the NLRP3/NF‐κB Signaling Pathway	14
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In vitro and in vivo antileishmanial activity of the hanging sedge flavonoids based on bio‐ guided fractionation assay	13
Chemical synthesis, biological activities, and molecular simulations of novel sulfonylurea compounds bearing ortho‐alkoxy substitutions	13
Synthetic corticotropins and the GABA‐receptor system: Direct and delayed effects	13
Design and synthesis of five‐membered heterocyclic derivatives of istradefylline with comparable pharmacological activity	13
Discovery of novel 1,3,5‐triazines as potent antibacterial agent against urinary tract infection‐causing clinical isolates of Escherichia coli via inhibition of DNA Gyrase	13
Issue Information	13
Structural and dynamic investigation of non‐synonymous variations in Renin–AGT complex revealed altered binding via hydrogen‐bonding network reprogramming to accelerate the hypertension pathway	13
Design, synthesis, antibacterial activity evaluation and molecular docking study of pleuromutilin derivatives bearing amide side chains	12
Lycopersene: A review on extraction, identification and purification and applications	12
LaSOM335, active against bladder cancer cells, interferes withLet‐60(hRas) and reducesCD73 expression/activity	12
Herbacetin Inhibits Human Fructose 1,6‐Bisphosphatase Among a Panel of Chromone Derivatives and Pyrazoles, Demonstrating Positive Effects on Insulin‐Resistant HepG2 Cells	12
Substrate‐based synthetic strategies and biological activities of 1,3,4‐oxadiazole: A review	12
Anticancer mechanisms of β‐carbolines	12
KH‐17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane	12
Berberine Ameliorates Pulmonary Fibrosis by Inactivating the Thrombospondin 2/Smad Homolog 2/3 Pathway	12
Therapeutic efficacy of caffeic acid phenethyl ester in cancer therapy: An updated review	12
Isoxazole and Pyrazole Derivatives of 28‐Oxo‐Allobetulone Target Viral Membrane Glycoprotein Hemagglutinin	11
Targeting Cancer Cell Proliferation Using Piperazine‐Linked Quinolinequinones: Mechanism and Metabolic Profile	11
Structure‐based discovery of Licoflavone B and Ginkgetin targeting c‐Myc G‐quadruplex to suppress c‐Myc transcription and myeloma growth	11
Click chemistry beyond metal‐catalyzed cycloaddition as a remarkable tool for green chemical synthesis of antifungal medications	11
Network pharmacology and in vitro experiments reveal sophoridine‐induced apoptosis and G1 phase arrest via ROS‐dependent PI3K/Akt/FoxO3a pathway	11
New class of benzothiophene morpholine analogues with high selectivity and affinity were designed and evaluated for anti‐drug addiction	11
A Comprehensive Review on the Advancements of Dual COX‐2/5‐LOX Inhibitors as Anti‐Inflammatory Drugs	11
Identification of miR‐3182 and miR‐3143 target genes involved in the cell cycle as a novel approach in TNBC treatment: A systems biology approach	11
Curcumin Regulates Microglia Polarization to Alleviate Ischemic Stroke by Targeting microRNA‐205‐5p/Kruppel‐Like Factor 2 (KLF2)/Activating Transcription Factor 2 (ATF2) Axis	11
The medicinal chemistry of piperazines: A review	11
Spalt‐Like Transcription Factor 4 Mediates Fatty Acid Oxidation to Foster 5‐Fluorouracil Resistance in Gastric Cancer Cells	10
Synthesis and biological activity profile of novel triazole/quinoline hybrids	10
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A comprehensive review on the research progress of PTP1B inhibitors as antidiabetics	10
Irreversible inhibitors of the proline racemase unveil innovative mechanism of action as antibacterial agents against Clostridioides difficile	10
Current Challenges With Highly Active Antiretroviral Therapy and New Hope and Horizon With CRISPR‐CAS9 Technology for HIV Treatment	10
Identification of Potent Leucine‐Rich Repeat Kinase 2 Inhibitors by Virtual Screening and Biological Evaluation	10
Syringic acid suppresses ferroptosis of skeletal muscle cells to alleviate lower limb ischemia/reperfusion injury in mice via the HMGB1 pathway	10
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Exploring Thiazole‐Based Heterocycles: Synthesis, Bioactivity, and Molecular Docking for Antimicrobial Applications	10
Design, Synthesis, and Biological Evaluation of New Benzimidazole‐1,2,4‐Triazole Derivatives as Potential Anticancer Agents	10
Multiple function of lncRNA MALAT1 in cancer occurrence and progression	10
Kaempferol exerts antioxidant effects in age‐related diminished ovarian reserve by regulating the HSP90/NRF2 pathway	10
Multi‐fluorine labeled indanone derivatives as potential MRI imaging probes for β‐Amyloid plaques	10
Synthesis of Novel Soritin Sulfonamide Derivatives as Potential α‐Glucosidase Inhibitor and Their Molecular Docking Studies	10
Issue Information	10
Correction to Plumbagin's Antiproliferative Mechanism in Human Cancer Cells: A Copper‐Dependent Cytotoxic Approach	10
Baicalein Targets MAPK9 to Induce Apoptosis of Hepatocellular Carcinoma Cells	10
Pyrrole‐Tethered Bisbenzoxazole Derivatives: Apoptosis‐Inducing Agents Targeting Breast Cancer Cells	9
Atropisomerism transforming anti‐cancer drug discovery	9
Curcumin inhibits malignant behavior of colorectal cancer cells by regulating M2 polarization of tumor‐associated macrophages and metastasis associated in colon cancer 1 (MACC1)	9
Local anaesthetic procaine derivatives protect rat against diabetic nephropathy via inhibition of DPP‐4, inflammation and oxidative stress	9
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Investigation of Potential Inhibitors of N‐Myristoyltransferase in Leishmania amazonensis: A Computational and Experimental Study	9
EGFR degraders in non‐small‐cell lung cancer: Breakthrough and unresolved issue	9
Pyrimidine derivatives as EGFR tyrosine kinase inhibitors in non‐small‐cell lung cancer: A comprehensive review	9
Structure‐Based Design of 2‐Aminopyrazolpyrimidopyridone Derivatives as New Rearranged During Transfection (RET) Kinase Inhibitors	9
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IGF2BP3 loss inhibits cell progression by upregulating has_circRNA_103820, and hsa_circRNA_103820‐encoded peptide inhibits cell progression by inactivating the AKT pathway in lung cancer	9
Issue Information	9
Synthesis of novel 5‐amido‐2‐carboxypyrazines as inhibitors of the type three secretion system of Salmonella enterica serovar Typhimurium	9
β‐elemene enhances cisplatin sensitivity of non‐small cell lung cancer cells via the miR‐17‐5p/STAT3 axis	9
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Optimized synthesis, polymer conjugation, and proof‐of‐concept studies of the gd‐IgA1 epitope for antibody‐scavenging therapies in IgA nephropathy	9
Synthesis and biological evaluation of novel 5,6‐dihydrobenzo[h]quinazoline derivatives as FLT3 inhibitors	9
SU5, a new Auraptene analog with improved metabolic stability, ameliorates nonalcoholic fatty liver disease in methionine‐ and choline‐deficient diet‐fed db/db mice	9
Sinigrin improves cerebral ischaemia‐reperfusion injury by inhibiting the TLR4 pathway‐mediated oxidative stress	8
Apelin‐13's Actions in Controlling Hypertension‐Related Cardiac Hypertrophy and the Expressions of Inflammatory Cytokines	8
The evaluation of isatin analogues as inhibitors of monoamine oxidase	8
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Plumbagin induces apoptosis, cell cycle arrest, and inhibits protein synthesis in LoVo colon cancer cells: A proteomic analysis	8
Exploring Flavonoids as Regulators of MMP‐2 and MMP‐9 in Cancer Pathogenesis	8
Systematic profiling of Taxol resistance and sensitivity to tubulin missence mutations at molecular and cellular levels	8
Chromone Derivatives as a Novel NOX4 Inhibitor: Design, Synthesis, and Regulation of ROS in Renal Fibroblast	8
Therapeutic implications of crocin in Parkinson's disease: A review of preclinical research	8
The mannose‐binding protein from Agaricus bisporus inhibits the growth of MDA‐MB‐231 spheroids	8
Exploring the cytotoxic potential of biflavones of Araucaria cunninghamii: Precise identification combined by LC‐HRMS‐metabolomics and database mining, targeted isolation, network pharmacology,	8
Combination of fenchone and sodium hyaluronate ameliorated constipation‐predominant irritable bowel syndrome and underlying mechanisms	8
Identification of tripeptides against tyrosine kinase domain of EGFR for lung cancer cell inhibition by in silico and in vitro studies	8
NMC‐4 Ameliorates Depression‐Like Behavior and Neuroinflammation Caused by Chronic Unpredictable Mild Stress	8

Synthesis and preliminary evaluation of benzylaminoimidazoline derivatives as novel norepinephrine transporter ligands	8
Dexmedetomidine Inhibits Ferroptosis by Regulating the SRY‐Box Transcription Factor 9/Divalent Metal Transporter‐1 Axis to Alleviate Cerebral Ischemia/Reperfusion Injury	8
Structural Insights Into Papain‐Derived Synthetic Antibacterial Peptides for Targeting Klebsiella pneumoniae	8
Design and Synthesized 3,4‐Dimethoxybenzene‐Based Fibrate Derivatives as Potential Hypolipidemic and Liver Protection Agents	8
Pioneering QSAR Modeling Study of FAP ‐Targeting Radiopharmaceuticals Used in Oncology	8
A single‐chain variable fragment‐anticancer lytic peptide (scFv‐ACLP) fusion protein for targeted cancer treatment	8
Design and Synthesis of 1,4‐Diformyl‐Piperazine Ferrostatin‐1 Derivatives as Novel Ferroptosis Inhibitors	7
Issue Information	7
Bioinformatic Analysis of the Protective Effects of Dexmedetomidine and Thrombopoietin Against Hypoxia/Reoxygenation‐Induced Injury in AC16 Cells	7
Quercetin inhibits breast cancer cell proliferation and survival by targeting Akt/mTOR/PTEN signaling pathway	7
Screening and introduction of key cell cycle microRNAs deregulated in colorectal cancer by integrated bioinformatics analysis	7
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Discovery and evaluation of biphenyl derivatives of 2‐iminobenzimidazoles as prototype dual PTP1B inhibitors and AMPK activators with in vivo antidiabetic activity	7
Identification of 5‐(3‐(methylsulfonyl)phenyl)‐3‐(4‐(methylsulfonyl)phenyl)‐3H‐imidazo[4,5‐b]pyridine as novel orally bioavailable and metabolically stable antimalarial compou	7
Computational prediction of Lee retention indices of polycyclic aromatic hydrocarbons by using machine learning	7
Amentoflavone attenuates cell proliferation and induces ferroptosis in human gastric cancer by miR‐496/ATF2 axis	7
Correction to Analysis of bioactive compounds using LC–ESI–MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifoliu	7
New pyrrolidine‐carboxamide derivatives as dual antiproliferative EGFR/CDK2 inhibitors	7
Puerarin Decreases the Expression of FUS‐Dependent MAPK4 to Inhibit the Development of Triple‐Negative Breast Cancer	7
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Heterocyclic and non‐heterocyclic arena of monocarboxylate transporter inhibitors to battle tumorigenesis	7
Anti‐metastatic Effects of Bee Venom and Melittin in Breast Cancer Cells by Upregulation of BRMS1 and DRG1 Genes	7
Identification of a novel ALDH1A3‐selective inhibitor by a chemical probe with unrelated bioactivity: An approach to affinity‐based drug target discovery	7
Research progress on the P2X7 receptor in liver injury and hepatocellular carcinoma	7
Berberine attenuates cognitive dysfunction and hippocampal apoptosis in rats with prediabetes	7
Medicarpin suppresses proliferation and triggeres apoptosis by upregulation of BID, BAX, CASP3, CASP8, and CYCS in glioblastoma	7
Study on the molecular mechanism of dihydromyricetin in alleviating liver cirrhosis based on network pharmacology	7
Ferulic Acid Inhibits Partial Epithelial‐Mesenchymal Transition in Renal Tubular Epithelial Cells and Mitigates Renal Interstitial Fibrosis by Regulating the HIF‐1α/Twist Signaling Pathway	7
Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking	7
A highly bioavailable curcumin formulation ameliorates inflammation cytokines and neurotrophic factors in mice with traumatic brain injury	7
Propofol inhibits the proliferation, invasion, migration, and angiogenesis of oral squamous cell carcinoma through circ_0008898‐mediated pathway	7
Spacered With Tetrazole Oleanolic and Ursolic Indolo‐Acids Are Strong Inhibitors of α‐Glucosidase	7
Long noncoding RNA SNHG7‐miRNA‐mRNA axes crosstalk with oncogenic signaling pathways in human cancers	7
Exendin‐4: A potential therapeutic strategy for Alzheimer's disease and Parkinson's disease	7
Hsa‐miR‐503‐5p regulates CTDSPL to accelerate cisplatin resistance and angiogenesis of lung adenocarcinoma cells	7
Myoinositol and methyl stearate increases rifampicin susceptibility among drug‐resistant Mycobacterium tuberculosis expressing Rv1819c	7
Elucidation of the mechanisms and molecular targets of KeChuanLiuWei‐Mixture for treatment of severe asthma based on network pharmacology	7
Curcumin affects apoptosis of colorectal cancer cells through ATF6‐mediated endoplasmic reticulum stress	6
Asiatic acid inhibits rheumatoid arthritis fibroblast‐like synoviocyte growth through the Nrf2/HO‐1/NF‐κB signaling pathway	6
Ligand and structure based hierarchical virtual screening cascade for finding novel epidermal growth factor receptor inhibitors	6
Edaravone Ameliorate Inflammation in Vitamin D3 and High Fat Diet Induced Atherosclerosis in Rat via Alteration of Inflammatory Pathway and Gut Microbiota	6
Development of potent inhibitors by fragment‐linking strategies	6
Design and biological characterization of a series of dual mechanism ERK1/2 inhibitors with a Triazolopyridinone core	6
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Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition	6
Therapeutic potentials of N‐acetylcysteine immobilized polyrhodanine nanoparticles toward acetaminophen‐induced acute hepatotoxicity in rat	6
Design, Hemisynthesis, Characterization, Molecular Docking, and Dynamics Evaluation of Novel Totarol‐1,2,3‐Triazole Derivatives as Leishmaniasis and Toxoplasmosis Agents	6
Enhancer of zeste homolog 2 exerts functions in gastric cancer development via modulating microRNA‐222‐3p methylation and WEE1 expression	6
Arctigenin Modulates Adipogenic‐Osteogenic Balance in the Bone Marrow Microenvironment of Ovariectomized Rats via the MEK1/PPARγ/Wnt/β‐Catenin Pathway	6
Transition metal complexes of hydrazones as potential antimicrobial and anticancer agents: A short review	6
Thienopyrimidine: Unveiling the Versatile Potential of a Promising Heterocyclic Scaffold in Drug Discovery	6
Nesfatin‐1 Reduces Cholic Acid‐Induced Intrahepatic Cholestasis of Pregnancy by Regulating the General Control Nonderepressible 2/Eukaryotic Initiation Factor 2α Pathway	6
Methyltransferase METTL3‐mediated maturation of miR‐4654 facilitates high glucose‐induced apoptosis and oxidative stress in lens epithelial cells via decreasing SOD2	6
Correction to “Nanoemulsion Based Lipid Nanoparticles for Effective Demethylcantharidin Delivery to Cure Liver Cancer”	6
Anticancer properties and pharmaceutical applications of ginsenoside compound K: A review	6
Comment on “Integrative Analysis of Ex Vivo Studies and Microarray Reveals the Novel Inhibitor Effects of Trehalose on the Pathogenesis of Pterygium”	6
Xanthones as potential α‐glucosidase non‐competition inhibitors: Synthesis, inhibitory activities, and in silico studies	6
Some 2‐[4‐(1H‐benzimidazol‐1‐yl) phenyl]‐1H‐benzimidazole derivatives overcome imatinib resistance by induction of apoptosis and reduction of P‐glycoprotein activity	6
An in silico comparative study of curcumin and 2‐deoxyuridine nucleoside derivatives: Reveals the role of angiogenin in ER stress‐induced apoptosis signaling	6
1,2,3‐Triazole Tethered Spiro[Indoline‐Oxirane] Derivatives Induce Anticancer Effects in Human Hepatoma Cells	6
Synthesis and antiglycation activity of 3‐phenacyl substituted thiazolium salts, new analogs of Alagebrium	6
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Ganoderic acid A improves osteoarthritis by regulating RANKL/OPG ratio	6
Synthesis and Investigation of Peptide–Drug Conjugates Comprising Camptothecin and a Human Protein‐Derived Cell‐Penetrating Peptide	6
Structural properties and immune‐enhancing activities of galactan isolated from red seaweed Grateloupia filicina	6
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Role of calcium dysregulation in Alzheimer's disease and its therapeutic implications	6
Antiproliferative Activity and Target Analysis of 18β‐Glycyrrhetinic Acid Derivatives Modified With α, β‐Unsaturated Carbonyl Groups	6
In silico optimization of analogs derived pro‐adrenomedullin peptide to evaluate antimicrobial potential	6
Could natural terpenes be an alternative for the treatment of neglected tropical diseases?	6
Quinoline‐based heterocyclic hydrazones: Design, synthesis, anti‐plasmodial assessment, and mechanistic insights	6
Design and synthesis of isatin derivatives as effective SARS‐CoV‐2 3CL protease inhibitors	6
Synthesis and Preliminary Anticancer Evaluation of 4‐C Derivatives of Diphyllin	6
Acacetin restrains the malignancy of esophageal squamous carcinoma cells via regulating JAK2/STAT3 pathway	6
Pyrrole‐based EGFR inhibitors for the treatment of NCSLC: Binding modes and SARs investigations	6
Discovery of New 4‐Aminoquinoline–Thiazolidinone Hybrid Analogs as Antiproliferative Agents Inhibiting TLR4–LPS‐Mediated Migration in Triple‐Negative Breast Cancer Cells	6
Structural modification of 2‐phenylquinoline‐4‐carboxylic acid containing SIRT3 inhibitors for the cancer differentiation therapy	6
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Downregulation of MDM2 by small interference RNA induces apoptosis and sensitizes MCF‐7 breast cells to resveratrol	6
Baicalin mitigated IL‐1β‐Induced osteoarthritis chondrocytes damage through activating mitophagy	6
Nardosinone suppresses monoiodoacetate‐induced osteoarthritis in rats: The key role of the miR‐218‐5p/NUMB axis	6
Dehydroepiandrosterone‐α‐2‐Deoxyglucoside Exhibits Enhanced Anticancer Effects in MCF‐7 Breast Cancer Cells and Inhibits Glucose‐6‐Phosphate Dehydrogenase Activity	6
Ginsenoside Rg3 alleviates the migration, invasion, and angiogenesis of lung cancer cells by inhibiting the expressions of cyclooxygenase‐2 and vascular endothelial growth factor	6
Transethosomes: Cutting edge approach for drug permeation enhancement in transdermal drug delivery system	6
Discovering novel derivatives of STAT3 and HDAC inhibitors with anti‐tumor activity	6
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Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application	6
Cytotoxic activity of quinolinequinones in cancer: In vitro studies, molecular docking, and ADME/PK profiling	6
Geraniol protects hippocampal CA1 neurons and improves functional outcomes in global model of stroke in rats	6