Chemical Biology & Drug Design

Article	Citations
SAR study of small molecule inhibitors of the programmed cell death‐1/programmed cell death‐ligand 1 interaction	216
Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease	96
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Elucidating specificity of an allosteric inhibitor WNK476 among With‐No‐Lysine kinase isoforms using molecular dynamic simulations	64
Estrone analogs as potential inhibitors targeting EGFR‐MAPK pathway in non‐small‐cell lung cancer	60
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Discovery of small molecule c‐Maf inhibitors using molecular docking‐based virtual screening, molecular dynamics simulation, and biological evaluation	48
Correction to Silencing PCMT1 enhances the sensitivity of breast cancer cells to paclitaxel through the PI3K/Akt/STMN1 pathway	48
Discussion on structure classification and regulation function of histone deacetylase and their inhibitor	45
A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease	45
Potential Modulatory Effects of Hesperidin on the JAK/STAT Pathway in Mesangial Proliferative Glomerulonephritis	44
Synthesis and antiviral activity of diverse heterocyclic scaffolds	44
Folate trapping is lethal to cancer cells	42
Effect of novel therapeutic medicine swertiamarin from Enicostema axillare in zebrafish infected with Salmonella typhi	40
Two new compounds from endemic Centaurea paphlagonica (Bornm.) Wagenitz and their cytotoxic activities	38
Investigating the Role of Quercetin, an Active Ingredient in Bazhen Decoction, in Targeting CXCL8 to Inhibit Macrophage M2 Polarization and Reshape the Immunological Microenviron	38
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation	36
Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway	36
Purification and structural analysis of a novel polysaccharide from Rehmannia Radix Praeparata	35
Caspase‐3: A primary target for natural and synthetic compounds for cancer therapy	35
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Issue Information	32
Why are heterocycles so special in medicinal chemistry?	32
Glycyrrhizic acid inhibits DNA damage repair and enhances cisplatin‐induced apoptosis of melanoma cells	31
Exploration of potential inhibitors for autophagy‐related protein 8 as antileishmanial agents	30

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Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin‐2‐one moiety of phenyl 4‐(2‐oxoimidazolidin‐1‐yl)benzenesulfonates	28
Design, synthesis and characterization of ethyl 3‐benzoyl‐7‐morpholinoindolizine‐1‐carboxylate as anti‐tubercular agents: In silico screening for possible target identification	28
C2‐linked alkynyl poly‐ethylene glycol(PEG) adenosine conjugates as water‐soluble adenosine receptor agonists	27
TMEM97 knockdown inhibits 5‐fluorouracil resistance by regulating epithelial‐mesenchymal transition and ABC transporter expression via inactivating the Akt/mTOR pathwa	26
Tetrazole: A privileged scaffold for the discovery of anticancer agents	25
BSV163/DOPE‐mediated TRAIL gene transfection acts synergistically with chemotherapy against cisplatin‐resistant ovarian cancer	25
Machine Learning‐Based Discovery of a Novel Noncovalent MurA Inhibitor as an Antibacterial Agent	24
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Orthogonal threading‐through‐β‐sheet design of lung cancer EGFR extracellular domain‐derived peptidic mimotopes binding to anti‐EGFR antibody	24
The Molecular Mechanism of Resveratrol in the Treatment of Chronic Rhinosinusitis Through a Combination of Network Pharmacology and In Vitro Validation	24
Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug‐carrier molecule for the treatment of glioblastoma	24
Dietary Natural Flavonoids: Intervention for MAO‐B Against Parkinson's Disease	23
Synthesis and evaluation of di‐heterocyclic benzazole compounds as potential antibacterial and anti‐biofilm agents against Staphylococcus aureus	23
miRNAs as key modulators between normal cells and tumor microenvironment interactions	23
Corrigendum	23
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Network pharmacology analysis and experimental evaluations of YH complex on androgenetic alopecia by regulating the androgenic‐apoptotic axis	22
Hybrid PABA‐glutamic acid conjugated 1,3,5‐triazine derivatives: Design, synthesis, and antimalarial activity screening targeting Plasmodium falciparum dihydro folate reductase enzym	22
Investigating potential mechanisms of vitamin D against thyroid cancer via network pharmacology and experimental validation	22
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Antiaggregant effects of (1,2,5‐oxadiazolyl)azasydnone ring assemblies as novel antiplatelet agents	21
A recent update on huprine and its hybrids as a potential multifunctional agent for the treatment of Alzheimer's disease	21
Friedlӓnder's synthesis of quinolines as a pivotal step in the development of bioactive heterocyclic derivatives in the current era of medicinal chemistry	21
In silico prediction of boiling point, octanol–water partition coefficient, and retention time index of polycyclic aromatic hydrocarbons through machine learning	20
Paclitaxel may inhibit migration and invasion of gastric cancer cells via nod‐like receptor family pyrin domain‐containing 3/caspase‐1/Gasdermin E mediated pyroptosis pathway	20
Methyl benzoate and cinnamate analogs as modulators of DNA methylation in hepatocellular carcinoma	19
Integrated bioinformatics analysis reveals the bidirectional effects of TSPAN6 for cisplatin resistance in lung cancer	19
Progress of SARS‐CoV‐2 Main protease peptide‐like inhibitors	19
The designation, synthesis, and affinity determination of affinity peptide for anthrax protective antigen	19
Exploring the Artificial Intelligence and Its Impact in Pharmaceutical Sciences: Insights Toward the Horizons Where Technology Meets Tradition	18
In vitro cytotoxicity and docking study of novel symmetric and asymmetric dihydropyridines and pyridines as EGFR tyrosine kinase inhibitors	18
Classification of beta‐site amyloid precursor protein cleaving enzyme 1 inhibitors by using machine learning methods	18
Predicting clinical trial outcomes using drug bioactivities through graph database integration and machine learning	18
Dexmedetomidine attenuates myocardial ischemia–reperfusion injury in hyperlipidemic rats by inhibiting inflammation, oxidative stress and NF‐κB	17
Praeruptorin A inhibits the activation of NF‐κB pathway and the expressions of inflammatory factors in poly (I:C)‐induced RAW264.7 cells	17
Small Molecule Inhibitors Targeting Cdc2‐Like Kinase 4: Advances, Challenges, and Opportunities	17
Sulfonated non‐saccharide molecules and human factor XIa: Enzyme inhibition and computational studies	17
Chemistry and biological evaluation of pyrido[4,3‐d]pyrimidines: A review	16
2, 4, 5‐Trideoxyhexopyranosides derivatives of diphyllin: Synthesis and anticancer activity	16
Quercetin Prevents Hyperuricemia Associated With Gouty Arthritis by Inactivating the NLRP3/NF‐κB Signaling Pathway	16
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An appraisal on synthetic and pharmaceutical perspectives of quinoxaline 1,4‐di‐N‐oxide scaffold	15
Curcumin activates the JNK signaling pathway to promote ferroptosis in colon cancer cells	15
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Antitumor and antioxidant activities of polysaccharides from the seaweed Durvillaea antarctica	14
Exploring the interactive mechanism of acarbose with the amylase SusG in the starch utilization system of the human gut symbiont Bacteroides thetaiotaomicron through molecular modeli	14
Design, synthesis, in vitro evaluation, and molecular modeling studies of N‐substituted benzomorphans, analogs of LP2, as novel MOR ligands	14
Design, synthesis, antibacterial activity evaluation and molecular docking study of pleuromutilin derivatives bearing amide side chains	14

Structural and dynamic investigation of non‐synonymous variations in Renin–AGT complex revealed altered binding via hydrogen‐bonding network reprogramming to accelerate the hypertension pathway	14
Glabridin inhibits urothelial bladder carcinoma cell growth in vitro and in vivo by inducing cell apoptosis and cell cycle arrest	14
Synthesis and evolution of neuroprotective effects of oxymatrine derivatives as anti‐Alzheimer’s disease agents	14
Lycopersene: A review on extraction, identification and purification and applications	14
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In vitro effects of thirty‐eight cardiac drugs on human serum paraoxonase	14
Chemical synthesis, biological activities, and molecular simulations of novel sulfonylurea compounds bearing ortho‐alkoxy substitutions	14
Synthesis and anti‐tumor activity evaluation of 1H‐pyrrolo[2,3‐b]pyridine‐2‐carboxamide derivatives with phenyl sulfonamide groups as potent RSK2 inhibitors	14
Herbacetin Inhibits Human Fructose 1,6‐Bisphosphatase Among a Panel of Chromone Derivatives and Pyrazoles, Demonstrating Positive Effects on Insulin‐Resistant HepG2 Cells	14
Discovery of novel 1,3,5‐triazines as potent antibacterial agent against urinary tract infection‐causing clinical isolates of Escherichia coli via inhibition of DNA Gyrase	14
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KH‐17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane	13
Anticancer mechanisms of β‐carbolines	13
Issue Information	13
In vitro and in vivo antileishmanial activity of the hanging sedge flavonoids based on bio‐ guided fractionation assay	13
Identification of miR‐3182 and miR‐3143 target genes involved in the cell cycle as a novel approach in TNBC treatment: A systems biology approach	13
Substrate‐based synthetic strategies and biological activities of 1,3,4‐oxadiazole: A review	13
Synthetic corticotropins and the GABA‐receptor system: Direct and delayed effects	13
Network pharmacology and in vitro experiments reveal sophoridine‐induced apoptosis and G1 phase arrest via ROS‐dependent PI3K/Akt/FoxO3a pathway	13
Design and synthesis of five‐membered heterocyclic derivatives of istradefylline with comparable pharmacological activity	13
A comprehensive review on the research progress of PTP1B inhibitors as antidiabetics	12
Curcumin Regulates Microglia Polarization to Alleviate Ischemic Stroke by Targeting microRNA‐205‐5p/Kruppel‐Like Factor 2 (KLF2)/Activating Transcription Factor 2 (ATF2) Axis	12
Irreversible inhibitors of the proline racemase unveil innovative mechanism of action as antibacterial agents against Clostridioides difficile	12
New class of benzothiophene morpholine analogues with high selectivity and affinity were designed and evaluated for anti‐drug addiction	12
The medicinal chemistry of piperazines: A review	12
LaSOM335, active against bladder cancer cells, interferes withLet‐60(hRas) and reducesCD73 expression/activity	12
Click chemistry beyond metal‐catalyzed cycloaddition as a remarkable tool for green chemical synthesis of antifungal medications	12
Baicalein Targets MAPK9 to Induce Apoptosis of Hepatocellular Carcinoma Cells	12
Therapeutic efficacy of caffeic acid phenethyl ester in cancer therapy: An updated review	12
Structure‐based discovery of Licoflavone B and Ginkgetin targeting c‐Myc G‐quadruplex to suppress c‐Myc transcription and myeloma growth	11
Issue Information	11
Issue Information	11
An insight into cytotoxic activity of flavonoids and sesquiterpenoids from selected plants of Asteraceae species	11
Correction to Plumbagin's Antiproliferative Mechanism in Human Cancer Cells: A Copper‐Dependent Cytotoxic Approach	11
Isoxazole and Pyrazole Derivatives of 28‐Oxo‐Allobetulone Target Viral Membrane Glycoprotein Hemagglutinin	11
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Curcumin inhibits malignant behavior of colorectal cancer cells by regulating M2 polarization of tumor‐associated macrophages and metastasis associated in colon cancer 1 (MACC1)	11
Design, Synthesis, and Biological Evaluation of New Benzimidazole‐1,2,4‐Triazole Derivatives as Potential Anticancer Agents	11
Berberine Ameliorates Pulmonary Fibrosis by Inactivating the Thrombospondin 2/Smad Homolog 2/3 Pathway	11
Pyrimidine derivatives as EGFR tyrosine kinase inhibitors in non‐small‐cell lung cancer: A comprehensive review	11
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Atropisomerism transforming anti‐cancer drug discovery	11
Synthesis of Novel Soritin Sulfonamide Derivatives as Potential α‐Glucosidase Inhibitor and Their Molecular Docking Studies	11
Multiple function of lncRNA MALAT1 in cancer occurrence and progression	10
Chromones: Privileged scaffold in anticancer drug discovery	10
EGFR degraders in non‐small‐cell lung cancer: Breakthrough and unresolved issue	10
Pyrrole‐Tethered Bisbenzoxazole Derivatives: Apoptosis‐Inducing Agents Targeting Breast Cancer Cells	10
Structure‐Based Design of 2‐Aminopyrazolpyrimidopyridone Derivatives as New Rearranged During Transfection (RET) Kinase Inhibitors	10
Kaempferol exerts antioxidant effects in age‐related diminished ovarian reserve by regulating the HSP90/NRF2 pathway	10
Multi‐fluorine labeled indanone derivatives as potential MRI imaging probes for β‐Amyloid plaques	10
Identification of Potent Leucine‐Rich Repeat Kinase 2 Inhibitors by Virtual Screening and Biological Evaluation	10
Synthesis and biological activity profile of novel triazole/quinoline hybrids	10
β‐elemene enhances cisplatin sensitivity of non‐small cell lung cancer cells via the miR‐17‐5p/STAT3 axis	10
Local anaesthetic procaine derivatives protect rat against diabetic nephropathy via inhibition of DPP‐4, inflammation and oxidative stress	9
Syringic acid suppresses ferroptosis of skeletal muscle cells to alleviate lower limb ischemia/reperfusion injury in mice via the HMGB1 pathway	9
Insights into the structure and drug design of benzimidazole derivatives targeting the epidermal growth factor receptor (EGFR)	9
Optimized synthesis, polymer conjugation, and proof‐of‐concept studies of the gd‐IgA1 epitope for antibody‐scavenging therapies in IgA nephropathy	9
Systematic profiling of Taxol resistance and sensitivity to tubulin missence mutations at molecular and cellular levels	9
A single‐chain variable fragment‐anticancer lytic peptide (scFv‐ACLP) fusion protein for targeted cancer treatment	9
Chromone Derivatives as a Novel NOX4 Inhibitor: Design, Synthesis, and Regulation of ROS in Renal Fibroblast	9
NMC‐4 Ameliorates Depression‐Like Behavior and Neuroinflammation Caused by Chronic Unpredictable Mild Stress	9
Synthesis of novel 5‐amido‐2‐carboxypyrazines as inhibitors of the type three secretion system of Salmonella enterica serovar Typhimurium	9
Exploring the cytotoxic potential of biflavones of Araucaria cunninghamii: Precise identification combined by LC‐HRMS‐metabolomics and database mining, targeted isolation, network pharmacology,	9
Identification of a novel ALDH1A3‐selective inhibitor by a chemical probe with unrelated bioactivity: An approach to affinity‐based drug target discovery	9
Synthesis, and antimalarial and antibacterial activities of marine alkaloids	9
The mannose‐binding protein from Agaricus bisporus inhibits the growth of MDA‐MB‐231 spheroids	9
Sinigrin improves cerebral ischaemia‐reperfusion injury by inhibiting the TLR4 pathway‐mediated oxidative stress	9
The evaluation of isatin analogues as inhibitors of monoamine oxidase	9
Combination of fenchone and sodium hyaluronate ameliorated constipation‐predominant irritable bowel syndrome and underlying mechanisms	8
Phthalimide‐(N‐alkylbenzylamine) cysteamide hybrids as multifunctional agents against Alzheimer’s disease: Design, synthesis, and biological evaluation	8
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Dexmedetomidine Inhibits Ferroptosis by Regulating the SRY‐Box Transcription Factor 9/Divalent Metal Transporter‐1 Axis to Alleviate Cerebral Ischemia/Reperfusion Injury	8
SU5, a new Auraptene analog with improved metabolic stability, ameliorates nonalcoholic fatty liver disease in methionine‐ and choline‐deficient diet‐fed db/db mice	8
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Synthesis and biological evaluation of novel 5,6‐dihydrobenzo[h]quinazoline derivatives as FLT3 inhibitors	8
Therapeutic implications of crocin in Parkinson's disease: A review of preclinical research	8
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Identification of tripeptides against tyrosine kinase domain of EGFR for lung cancer cell inhibition by in silico and in vitro studies	8

Synthesis and preliminary evaluation of benzylaminoimidazoline derivatives as novel norepinephrine transporter ligands	8
Synthesis and anti‐diabetic activity of novel biphenylsulfonamides as glucagon receptor antagonists	8
Myoinositol and methyl stearate increases rifampicin susceptibility among drug‐resistant Mycobacterium tuberculosis expressing Rv1819c	7
Radiosynthesis and in silico bioevaluation of 131I‐Sulfasalazine as a highly selective radiotracer for imaging of ulcerative colitis	7
Design and Synthesis of 1,4‐Diformyl‐Piperazine Ferrostatin‐1 Derivatives as Novel Ferroptosis Inhibitors	7
Identification of 5‐(3‐(methylsulfonyl)phenyl)‐3‐(4‐(methylsulfonyl)phenyl)‐3H‐imidazo[4,5‐b]pyridine as novel orally bioavailable and metabolically stable antimalarial compou	7
IGF2BP3 loss inhibits cell progression by upregulating has_circRNA_103820, and hsa_circRNA_103820‐encoded peptide inhibits cell progression by inactivating the AKT pathway in lung cancer	7
Computational prediction of Lee retention indices of polycyclic aromatic hydrocarbons by using machine learning	7
Heterocyclic and non‐heterocyclic arena of monocarboxylate transporter inhibitors to battle tumorigenesis	7
Hsa‐miR‐503‐5p regulates CTDSPL to accelerate cisplatin resistance and angiogenesis of lung adenocarcinoma cells	7
Preparation and antioxidant activity of phosphorylated polysaccharide from purple sweet potato	7
Discovery and evaluation of biphenyl derivatives of 2‐iminobenzimidazoles as prototype dual PTP1B inhibitors and AMPK activators with in vivo antidiabetic activity	7
Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking	7
Apelin‐13's Actions in Controlling Hypertension‐Related Cardiac Hypertrophy and the Expressions of Inflammatory Cytokines	7
Design, synthesis, and biological evaluation of benzo[b]thiophene 1,1‐dioxide derivatives as potent STAT3 inhibitors	7
Elucidation of the mechanisms and molecular targets of KeChuanLiuWei‐Mixture for treatment of severe asthma based on network pharmacology	7
Puerarin Decreases the Expression of FUS‐Dependent MAPK4 to Inhibit the Development of Triple‐Negative Breast Cancer	7
Medicarpin suppresses proliferation and triggeres apoptosis by upregulation of BID, BAX, CASP3, CASP8, and CYCS in glioblastoma	7
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O‐prenylated carbostyrils as a novel class of 15‐lipoxygenase inhibitors: Synthesis, characterization, and inhibitory assessment	7
Correction to Analysis of bioactive compounds using LC–ESI–MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifoliu	7
Design, synthesis, and antitumor activity evaluation of pretubulysin analogs	7
Research progress on the P2X7 receptor in liver injury and hepatocellular carcinoma	7
Plumbagin induces apoptosis, cell cycle arrest, and inhibits protein synthesis in LoVo colon cancer cells: A proteomic analysis	7
Screening and introduction of key cell cycle microRNAs deregulated in colorectal cancer by integrated bioinformatics analysis	7
Propofol inhibits the proliferation, invasion, migration, and angiogenesis of oral squamous cell carcinoma through circ_0008898‐mediated pathway	7
Amentoflavone attenuates cell proliferation and induces ferroptosis in human gastric cancer by miR‐496/ATF2 axis	7
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Ginsenoside Rg3 alleviates the migration, invasion, and angiogenesis of lung cancer cells by inhibiting the expressions of cyclooxygenase‐2 and vascular endothelial growth factor	6
Bioinformatic Analysis of the Protective Effects of Dexmedetomidine and Thrombopoietin Against Hypoxia/Reoxygenation‐Induced Injury in AC16 Cells	6
Quinoline‐based heterocyclic hydrazones: Design, synthesis, anti‐plasmodial assessment, and mechanistic insights	6
The flavonoid Astragalin shows anti‐tumor activity and inhibits PI3K/AKT signaling in gastric cancer	6
Transition metal complexes of hydrazones as potential antimicrobial and anticancer agents: A short review	6
Comment on “Integrative Analysis of Ex Vivo Studies and Microarray Reveals the Novel Inhibitor Effects of Trehalose on the Pathogenesis of Pterygium”	6
Synthesis and antiglycation activity of 3‐phenacyl substituted thiazolium salts, new analogs of Alagebrium	6
Antibiotic–cell‐penetrating peptide conjugates targeting challenging drug‐resistant and intracellular pathogenic bacteria	6
Issue Information	6
Cytotoxic activity of quinolinequinones in cancer: In vitro studies, molecular docking, and ADME/PK profiling	6
Exendin‐4: A potential therapeutic strategy for Alzheimer's disease and Parkinson's disease	6
Long noncoding RNA SNHG7‐miRNA‐mRNA axes crosstalk with oncogenic signaling pathways in human cancers	6
Discovering novel derivatives of STAT3 and HDAC inhibitors with anti‐tumor activity	6
Spacered With Tetrazole Oleanolic and Ursolic Indolo‐Acids Are Strong Inhibitors of α‐Glucosidase	6
Structural modification of 2‐phenylquinoline‐4‐carboxylic acid containing SIRT3 inhibitors for the cancer differentiation therapy	6
Asiatic acid inhibits rheumatoid arthritis fibroblast‐like synoviocyte growth through the Nrf2/HO‐1/NF‐κB signaling pathway	6
Analysis of the binding modes of the first‐ and second‐generation antiandrogens with respect to F876L mutation	6
Extraction, chemical modification, and antioxidant activities of Daucus carota polysaccharide	6
Berberine attenuates cognitive dysfunction and hippocampal apoptosis in rats with prediabetes	6
Study on the molecular mechanism of dihydromyricetin in alleviating liver cirrhosis based on network pharmacology	6
Development of potent inhibitors by fragment‐linking strategies	6
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Anti‐metastatic Effects of Bee Venom and Melittin in Breast Cancer Cells by Upregulation of BRMS1 and DRG1 Genes	6
Correction to “Nanoemulsion Based Lipid Nanoparticles for Effective Demethylcantharidin Delivery to Cure Liver Cancer”	6
In silico optimization of analogs derived pro‐adrenomedullin peptide to evaluate antimicrobial potential	6
Downregulation of MDM2 by small interference RNA induces apoptosis and sensitizes MCF‐7 breast cells to resveratrol	5
Cell‐penetrating peptide conjugates of indole‐3‐acetic acid‐based DNA primase/Gyrase inhibitors as potent anti‐tubercular agents against planktonic and biofilm culture of Mycobacterium smegmatis	5
An in silico comparative study of curcumin and 2‐deoxyuridine nucleoside derivatives: Reveals the role of angiogenin in ER stress‐induced apoptosis signaling	5
Identification of novel P2X7R antagonists by using structure‐based virtual screening and cell‐based assays	5
Role of calcium dysregulation in Alzheimer's disease and its therapeutic implications	5
Transethosomes: Cutting edge approach for drug permeation enhancement in transdermal drug delivery system	5
Synthesis and Preliminary Anticancer Evaluation of 4‐C Derivatives of Diphyllin	5
Aptamer‐siRNA chimeras: Promising tools for targeting HER2 signaling in cancer	5
Synthesis, biological evaluation, and molecular modeling studies of acetophenones‐tethered 1,2,4‐triazoles and their oximes as epidermal growth factor receptor inhibitors	5
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Design and biological characterization of a series of dual mechanism ERK1/2 inhibitors with a Triazolopyridinone core	5
Formulation, optimization and characterization of raloxifene hydrochloride loaded PLGA nanoparticles by using Taguchi design for breast cancer application	5
Design, synthesis, and structure–activity relationship studies of the anaephene antibiotics	5
Structural properties and immune‐enhancing activities of galactan isolated from red seaweed Grateloupia filicina	5
Ganoderic acid A improves osteoarthritis by regulating RANKL/OPG ratio	5
Xanthones as potential α‐glucosidase non‐competition inhibitors: Synthesis, inhibitory activities, and in silico studies	5
Baicalin mitigated IL‐1β‐Induced osteoarthritis chondrocytes damage through activating mitophagy	5
Curcumin affects apoptosis of colorectal cancer cells through ATF6‐mediated endoplasmic reticulum stress	5
Ligand and structure based hierarchical virtual screening cascade for finding novel epidermal growth factor receptor inhibitors	5
New pyrrolidine‐carboxamide derivatives as dual antiproliferative EGFR/CDK2 inhibitors	5
Geraniol protects hippocampal CA1 neurons and improves functional outcomes in global model of stroke in rats	5
Pyrrole‐based EGFR inhibitors for the treatment of NCSLC: Binding modes and SARs investigations	5
Identification of an AXL kinase inhibitor in triple‐negative breast cancer by structure‐based virtual screening and bioactivity test	5
Polyphyllin VII Enhances the Sensitivity of Prostate Cancer Cells to Docetaxel by Promoting Mitochondrial Dysfunction and Inducing Ferroptosis	5
Antitrypanosomal activity of new semi‐synthetic bergenin derivatives	5
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Design, Hemisynthesis, Characterization, Molecular Docking, and Dynamics Evaluation of Novel Totarol‐1,2,3‐Triazole Derivatives as Leishmaniasis and Toxoplasmosis Agents	5
Mitotic Arrest Deficient 2 Like 1 Contributes to Colorectal Cancer Cell Migration, Invasion, and Oxaliplatin Resistance Through the Wnt/β‐Catenin Pathway	5
Nardosinone suppresses monoiodoacetate‐induced osteoarthritis in rats: The key role of the miR‐218‐5p/NUMB axis	5
Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition	5
Some 2‐[4‐(1H‐benzimidazol‐1‐yl) phenyl]‐1H‐benzimidazole derivatives overcome imatinib resistance by induction of apoptosis and reduction of P‐glycoprotein activity	5
Methyltransferase METTL3‐mediated maturation of miR‐4654 facilitates high glucose‐induced apoptosis and oxidative stress in lens epithelial cells via decreasing SOD2	5
A highly bioavailable curcumin formulation ameliorates inflammation cytokines and neurotrophic factors in mice with traumatic brain injury	5
Quercetin inhibits breast cancer cell proliferation and survival by targeting Akt/mTOR/PTEN signaling pathway	5
Anticancer properties and pharmaceutical applications of ginsenoside compound K: A review	5
Design and synthesis of isatin derivatives as effective SARS‐CoV‐2 3CL protease inhibitors	5
Design and development of novel fasudil derivatives as potent antibreast cancer agent that improves intestinal flora and intestinal barrier function in rats	5
Synthesis and activities of acetylcholinesterase inhibitors	5
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Novel candidates in the clinical development pipeline for TB drug development and their synthetic approaches	5
Edaravone Ameliorate Inflammation in Vitamin D3 and High Fat Diet Induced Atherosclerosis in Rat via Alteration of Inflammatory Pathway and Gut Microbiota	5