Chemical Biology & Drug Design

Papers
(The H4-Index of Chemical Biology & Drug Design is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Alpha‐amylase as molecular target for treatment of diabetes mellitus: A comprehensive review145
Caspase‐3: A primary target for natural and synthetic compounds for cancer therapy87
Application of molecular dynamics simulation in biomedicine63
Chromones: Privileged scaffold in anticancer drug discovery55
Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway46
Preparation, structure, and properties of tea polysaccharide44
Therapeutic potential and pharmacological activities of β‐eudesmol41
Quinoline‐derivatives as privileged scaffolds for medicinal and pharmaceutical chemists: A comprehensive review40
SARS‐CoV‐2 and its variants of concern including Omicron: A never ending pandemic39
Computational design and modeling of nanobodies toward SARS‐CoV‐2 receptor binding domain38
Deciphering the detailed structure–activity relationship of coumarins as Monoamine oxidase enzyme inhibitors—An updated review38
Repurposing potential of FDA‐approved and investigational drugs for COVID‐19 targeting SARS‐CoV‐2 spike and main protease and validation by machine learning algorithm37
Discovery of two novel ALKBH5 selective inhibitors that exhibit uncompetitive or competitive type and suppress the growth activity of glioblastoma multiforme33
Pyrimidine: An elite heterocyclic leitmotif in drug discovery‐synthesis and biological activity32
Extraction, derivatization, and antioxidant activity of Morinda citrifolia polysaccharide31
Machine learning approaches and their applications in drug discovery and design31
Specific delivering of RNAi using Spike's aptamer‐functionalized lipid nanoparticles for targeting SARS‐CoV‐2: A strong anti‐Covid drug in a clinical case study30
Focal adhesion kinase—An emerging viable target in cancer and development of focal adhesion kinase inhibitors29
Alantolactone: A sesquiterpene lactone with diverse pharmacological effects28
Evolution of peptide nucleic acid with modifications of its backbone and application in biotechnology28
Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition27
A minireview of 1,2,3‐triazole hybrids with O‐heterocycles as leads in medicinal chemistry27
Recent progress in materials development and biological properties of GTR membranes for periodontal regeneration25
Novel imidazo[2,1‐b]thiazole‐based anticancer agents as potential focal adhesion kinase inhibitors: Synthesis, in silico and in vitro evaluation25
Silicon switch: Carbon–silicon Bioisosteric replacement as a strategy to modulate the selectivity, physicochemical, and drug‐like properties in anticancer pharmacophores25
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