OOIR: Observatory of International Research

Papers

(The H4-Index of Chemical Biology & Drug Design is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
SAR study of small molecule inhibitors of the programmed cell death‐1/programmed cell death‐ligand 1 interaction	216
Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease	96
Cover Image	79
Elucidating specificity of an allosteric inhibitor WNK476 among With‐No‐Lysine kinase isoforms using molecular dynamic simulations	64
Cover Image	60
Estrone analogs as potential inhibitors targeting EGFR‐MAPK pathway in non‐small‐cell lung cancer	60
Discovery of small molecule c‐Maf inhibitors using molecular docking‐based virtual screening, molecular dynamics simulation, and biological evaluation	48
Correction to Silencing PCMT1 enhances the sensitivity of breast cancer cells to paclitaxel through the PI3K/Akt/STMN1 pathway	48
A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease	45
Discussion on structure classification and regulation function of histone deacetylase and their inhibitor	45
Synthesis and antiviral activity of diverse heterocyclic scaffolds	44
Potential Modulatory Effects of Hesperidin on the JAK/STAT Pathway in Mesangial Proliferative Glomerulonephritis	44
Folate trapping is lethal to cancer cells	42
Effect of novel therapeutic medicine swertiamarin from Enicostema axillare in zebrafish infected with Salmonella typhi	40
Investigating the Role of Quercetin, an Active Ingredient in Bazhen Decoction, in Targeting CXCL8 to Inhibit Macrophage M2 Polarization and Reshape the Immunological Microenviron	38
Two new compounds from endemic Centaurea paphlagonica (Bornm.) Wagenitz and their cytotoxic activities	38
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation	36
Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway	36
Caspase‐3: A primary target for natural and synthetic compounds for cancer therapy	35
Purification and structural analysis of a novel polysaccharide from Rehmannia Radix Praeparata	35
Cover Image	34
Why are heterocycles so special in medicinal chemistry?	32
Issue Information	32
Glycyrrhizic acid inhibits DNA damage repair and enhances cisplatin‐induced apoptosis of melanoma cells	31
	30

Exploration of potential inhibitors for autophagy‐related protein 8 as antileishmanial agents	30
Design, synthesis and characterization of ethyl 3‐benzoyl‐7‐morpholinoindolizine‐1‐carboxylate as anti‐tubercular agents: In silico screening for possible target identification	28
Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin‐2‐one moiety of phenyl 4‐(2‐oxoimidazolidin‐1‐yl)benzenesulfonates	28