Chemical Biology & Drug Design

Papers
(The H4-Index of Chemical Biology & Drug Design is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
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Purification and structural analysis of a novel polysaccharide from Rehmannia Radix Praeparata66
SAR study of small molecule inhibitors of the programmed cell death‐1/programmed cell death‐ligand 1 interaction62
Estrone analogs as potential inhibitors targeting EGFR‐MAPK pathway in non‐small‐cell lung cancer56
Folate trapping is lethal to cancer cells52
Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development51
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation47
Synthesis and antiviral activity of diverse heterocyclic scaffolds42
Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease42
Potential Modulatory Effects of Hesperidin on the JAK/STAT Pathway in Mesangial Proliferative Glomerulonephritis42
Investigating the Role of Quercetin, an Active Ingredient in Bazhen Decoction, in Targeting CXCL8 to Inhibit Macrophage M2 Polarization and Reshape the Immunological Microenviron40
Two new compounds from endemic Centaurea paphlagonica (Bornm.) Wagenitz and their cytotoxic activities40
A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease40
Discussion on structure classification and regulation function of histone deacetylase and their inhibitor39
Discovery of small molecule c‐Maf inhibitors using molecular docking‐based virtual screening, molecular dynamics simulation, and biological evaluation38
Correction to Silencing PCMT1 enhances the sensitivity of breast cancer cells to paclitaxel through the PI3K/Akt/STMN1 pathway36
Effect of novel therapeutic medicine swertiamarin from Enicostema axillare in zebrafish infected with Salmonella typhi36
Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway36
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Exploration of potential inhibitors for autophagy‐related protein 8 as antileishmanial agents33
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Orthogonal threading‐through‐β‐sheet design of lung cancer EGFR extracellular domain‐derived peptidic mimotopes binding to anti‐EGFR antibody32
Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin‐2‐one moiety of phenyl 4‐(2‐oxoimidazolidin‐1‐yl)benzenesulfonates31
Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug‐carrier molecule for the treatment of glioblastoma30
miRNAs as key modulators between normal cells and tumor microenvironment interactions29
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Corrigendum29
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