Regenerative Medicine

Article	Citations
National human embryo and embryoid research policies: a survey of 22 top research-intensive countries	56
The use of innovative payment mechanisms for gene therapies in Europe and the USA	33
Adipose-derived stem cell exosomes facilitate rotator cuff repair by mediating tendon-derived stem cells	29
miR-19a/19b-loaded exosomes in combination with mesenchymal stem cell transplantation in a preclinical model of myocardial infarction	28
Breeding brains? Patients’ and laymen’s perspectives on cerebral organoids	28
Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice	26
Intra-articular injections of allogeneic human adipose-derived mesenchymal progenitor cells in patients with symptomatic bilateral knee osteoarthritis: a Phase I pilot study	23
The biological processes during wound healing	22
Mesenchymal stem cells modifications for enhanced bone targeting and bone regeneration	22
Corneal epithelium tissue engineering: recent advances in regeneration and replacement of corneal surface	19
Challenges in corneal endothelial cell culture	18
FGF2: a key regulator augmenting tendon-to-bone healing and cartilage repair	17
The effects of polydeoxyribonucleotide on wound healing and tissue regeneration: a systematic review of the literature	16
Platelet lysate: a promising candidate in regenerative medicine	16
Biomimicry in 3D printing design: implications for peripheral nerve regeneration	15
Clinical effectiveness of anorganic bovine-derived hydroxyapatite matrix/cell-binding peptide grafts for regeneration of periodontal defects: a systematic review and meta-analysis	14
Treatment of traumatic optic neuropathy using human placenta-derived mesenchymal stem cells in Asian patients	14
Mechanisms underlying the therapeutic potential of mesenchymal stem cells in atherosclerosis	13
Development of a decellularized porcine bone matrix for potential applications in bone tissue regeneration	13
Negative pressure wound therapy promotes wound healing by suppressing macrophage inflammation in diabetic ulcers	13
Regenerative engineering: a review of recent advances and future directions	13
Autologous fat grafting for nerve regeneration and neuropathic pain: current state from bench-to-bedside	13
Modeling ALS using iPSCs: is it possible to reproduce the phenotypic variations observed in patients in vitro?	12
LncRNA MALAT1 from human adipose-derived stem cell exosomes accelerates wound healing via miR-378a/FGF2 axis	12
Combination of preconditioned adipose-derived mesenchymal stem cells and platelet-rich plasma improves the repair of osteoarthritis in rat	12

Regenerative medicine clinical readiness	12
Adipose tissue-derived regenerative cells improve implantation of fertilized eggs in thin endometrium	11
Adipose tissue-derived mesenchymal stem cells for breast tissue regeneration	11
Extracellular matrix extraction techniques and applications in biomedical engineering	10
Paracrine effect of human adipose-derived stem cells on lymphatic endothelial cells	10
Real-world evidence of mesenchymal stem cell therapy in knee osteoarthritis: a large prospective two-year case series	10
Improved harmonization of critical characterization assays across cell therapies	10
Cellular and biological factors involved in healing wounds and burns and treatment options in tissue engineering	10
Evaluation of autologous adipose-derived mesenchymal stem cell therapy in focal chondral defects of the knee: a pilot case series	10
Mesenchymal stem cell therapy combined with arthroscopic abrasion arthroplasty regenerates cartilage in patients with severe knee osteoarthritis: a case series	10
Research progress on the regulatory role of microRNAs in spinal cord injury	10
Vascularization strategies for tissue engineering for tracheal reconstruction	9
Adipose-derived mesenchymal stem cells ameliorate lung epithelial injury through mitigating of oxidative stress in mustard lung	9
Is right to try being tried? Using crowdfunding data to better understand usage of nontrial pre-approval access pathways	9
Clinical use of autologous micro-fragmented fat progressively restores pain and function in shoulder osteoarthritis	9
Platelet-rich plasma: are the obtaining methods, classification and clinical outcome always connected?	9
Ultrasound-guided intra-articular injection of expanded umbilical cord mesenchymal stem cells in knee osteoarthritis: a safety/efficacy study with MRI data	9
Research progress in seed cells for cartilage tissue engineering	8
Digital regenerative medicine and surgery pedagogy for virtual learning in the time of COVID-19	8
Regenerative outlook: offering global solutions for equitable care	8
Characterization and bioassays of extracellular vesicles extracted by tangential flow filtration	8
microRNA-148a-3p-targeting p300 protects against osteoblast differentiation and osteoporotic bone reconstruction	8
Exosomes: the latest in regenerative aesthetics	8
LncRNA X inactive-specific transcript promotes osteoclast differentiation through Tgif2 by acting as a ceRNA of miR-590-3p in a murine model	7
Understanding neural stem cell regulation in vivo and applying the insights to cell therapy for strokes	7
Adipose tissue versus stem cell-derived small extracellular vesicles to enhance the healing of acute burns	7
Comparative lessons in regenerative medicine readiness: learning from the UK and Japanese experience	7
Sources, isolation strategies and therapeutic outcome of exosomes at a glance	7
Comparability: what we can learn from the review of advanced therapy medicinal products	7
Purified exosome product enhances chondrocyte survival and regeneration by modulating inflammation and promoting chondrogenesis	7
Regenerative medicine and traumatic brain injury: from stem cell to cell-free therapeutic strategies	7
Digital readiness in 3D bioprinting: software, governance and hospitals’ proto-clinical interfaces	7
Evaluating the FDA regenerative medicine framework: opportunities for stakeholders	7
Novel assessment of leukocyte-rich platelet-rich plasma on functional and patient-reported outcomes in knee osteoarthritis: a pilot study	7
Toward next-generation advanced therapies: extracellular vesicles and cell therapy – partners or competitors?	7
Platelet-rich plasma for treatment of chronic proximal hamstring tendinopathy	7
Platelet-derived exosomes induce cell proliferation and wound healing in human endometrial cells	7
Mesenchymal stem cell application for treatment of neuroinflammation-induced cognitive impairment in mice	7
Recombinant human FGF-2 therapy for osteonecrosis of the femoral head: 5-year follow-up	7
Astragalus and human mesenchymal stem cells promote wound healing by mediating immunomodulatory effects through paracrine signaling	7
Modeling policy development: examining national governance of stem cell-based embryo models	7
Regulating advanced therapy medicinal products through the Hospital Exemption: an analysis of regulatory approaches in nine EU countries	7
Decellularized bovine aorta as a promising 3D elastin scaffold for vascular tissue engineering applications	7
Neuroprotective effect of bone marrow-derived mesenchymal stem cell secretome in 6-OHDA-induced Parkinson's disease	6
Regenerative medicine lexicon	6
Do knee injection portals affect clinical results of bone marrow aspirate concentrate injection in the treatment of osteoarthritis? A prospective randomized controlled study	6
Effects of nicotine on the translation of stem cell therapy	6
Photoencapsulated-mesenchymal stromal cells in biodegradable thiol-acrylate hydrogels enhance regeneration of craniofacial bone tissue defects	6
Central versus peripheral nervous system regeneration: is there an exception for cranial nerves?	6
The safety and effectiveness of bone marrow concentrate injection for knee and hip osteoarthritis: a Canadian cohort	6

The influence of sodium citrate on the characteristics and biological activity of plasma rich in growth factors	6
Mesenchymal stem cell-derived exosomes: therapeutic implications for rotator cuff injury	6
Human periodontal ligament stem cells with distinct osteogenic potential induce bone formation in rat calvaria defects	6
Evaluation of institutional readiness at sites within the UK NHS using a novel advanced therapy medicinal product assessment tool	5
Adipose stem cell secretion combined with biomaterials facilitates large-area wound healing	5
Online seminars as an information source for direct-to-consumer stem cell therapy	5
Treatment strategies for meniscal lesions: from past to prospective therapeutics	5
Short-term outcomes after pure bone marrow aspirate injection for severe knee osteoarthritis: a case series	5
Understanding the role of digital platforms in technology readiness	5
Monocytes recruitment blocking synergizes with mesenchymal stem cell transplantation for treating myocardial infarction	5
Delivery of hepatocyte growth factor mRNA from nanofibrillar scaffolds in a pig model of peripheral arterial disease	5
Reimbursement and pricing of regenerative medicine in South Korea: key factors for achieving reimbursement	5
Challenges in the market access of regenerative medicines, and implications for manufacturers and decision-makers: a systematic review	5
Bibliometric analysis of the top 50 highly cited articles on platelet-rich plasma in osteoarthritis and tendinopathy	5
Recombinant human FGF-2 for the treatment of early-stage osteonecrosis of the femoral head: TRION, a single-arm, multicenter, Phase II trial	5
The regulatory challenge of 3D bioprinting	5
Restoration of cartilage defects using a superparamagnetic iron oxide-labeled adipose-derived mesenchymal stem cell and TGF-β3-loaded bilayer PLGA construct	5
Spatiotemporal readiness is key to preparing regenerative medicine for the clinic	5
Mesenchymal stem cell-derived neural progenitors attenuate proinflammatory microglial activation via paracrine mechanisms	4
Preclinical study for the treatment of diabetes mellitus using β-like cells derived from human dental pulp stem cells	4
Exosomal miR-150 derived from BMSCs inhibits TNF-α-mediated osteoblast apoptosis in osteonecrosis of the femoral head by GREM1/NF-κB signaling	4
Hope on the horizon: Wharton's jelly mesenchymal stem cells in the fight against COVID-19	4
Stem cell therapies as a therapeutic option to counter chemo brain: a negative effect of cancer treatment	4
Current challenges of retinal ganglion cell regeneration	4
Biomaterials and stem cells as drug/gene-delivery vehicles for Parkinson's treatment: an update	4
More than 500 million years of evolution in a fibrin-based therapeutic scaffold	4
Novel hydrogel system eliminates subculturing and improves retention of nonsenescent mesenchymal stem cell populations	4
A pulsed current electric field alters protein expression creating a wound healing phenotype in human skin cells	4
Exosomes derived from human dental pulp stem cells increase flap survival with ischemia-reperfusion injuries	4
Clinical applications of pluripotent stem cells and their derivatives: current status and future perspectives	4
One health in regenerative medicine: report on the second Havemeyer symposium on regenerative medicine in horses	4
Personalized multitarget biologic injection in the spine: prospective case series of multitarget platelet-rich plasma for low back pain	4
Photoencapsulated-BMP2 in visible light-cured thiol-acrylate hydrogels for craniofacial bone tissue engineering	4
Association of mesenchymal stem cells derived from bone marrow and adipose tissue enhances bone repair in rat calvarial defects	4
Emerging workforce readiness in regenerative healthcare	4
Recent advances in the design of cardiovascular materials for biomedical applications	4
Strategies of immobilizing BMP-2 with 3D-printed scaffolds to improve osteogenesis	4
The Glossary for Cell & Gene Therapy and Regenerative Medicine 2020	4
Bone regeneration in rabbit calvarial defects using PRGF and adipose-derived stem cells: histomorphometrical analysis	3
Current knowledge and future perspectives on exosomes in the field of regenerative medicine: a bibliometric analysis	3
Combined use of calcium phosphate cement, mesenchymal stem cells and platelet-rich plasma for bone regeneration in critical-size defect of the femoral condyle in mini-pigs	3
Acellular collagen–glycosaminoglycan matrix promotes functional recovery in a rat model of volumetric muscle loss	3
Regenerative readiness: innovation meets sociology	3
Use of cord blood platelet gel to enhance healing of deep surgical site dehiscences after peripheral bypass	3
Roles and responsibilities in stem cell research: a focus group study with stem cell researchers and patients	3
Human pluripotent stem cells: genetic instability or stability?	3
Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19	3
A new model of chronic peripheral nerve compression for basic research and pharmaceutical drug testing	3
Experimental study of negative pressure wound therapy combined with platelet-rich fibrin for bone-exposed wounds	3
Alternatives to endokeratoplasty: an attempt towards reducing global demand of human donor corneas	3
Pain and functional outcomes of the sacroiliac joint after platelet-rich plasma injection: a descriptive review	3
Treatment of resistant chronic central serous chorioretinopathy via platelet-rich plasma with electromagnetic stimulation	3
Adverse events related to unapproved stem cell products and other regenerative interventions: recommendations for more robust regulation of the direct-to-consumer marketplace	3
Evaluation of the effect of subtenon autologous platelet-rich plasma injections on visual functions in patients with retinitis pigmentosa	3
Facilitated self-assembly of a prevascularized dermal/epidermal collagen scaffold	3
Potential of mesenchymal stem cell-derived conditioned medium/secretome as a therapeutic option for ocular diseases	3
Applications of bacteria and their derived biomaterials for repair and tissue regeneration	3
Critical elements in tissue engineering of craniofacial malformations	3
Exosomes from artesunate-treated bone marrow-derived mesenchymal stem cells transferringSNHG7to promote osteogenesis via TAF15-RUNX2 pathway	3
Identification of the MALAT1/miR-106a-5p/ZNF148 feedback loop in regulating HaCaT cell proliferation, migration and apoptosis	3
Platelet-rich plasma for the treatment of adolescent late-stage femoral head necrosis: a case report	3
Systematic investigation and comparison of US FDA-approved immunosuppressive drugs FK506, cyclosporine and rapamycin for neuromuscular regeneration following chronic nerve compression injury	3
Developing innovation governance readiness in regenerative medicine: lessons learned from the Macchiarini crisis	3
Regeneration of mandibular osteoradionecrosis with autologous cross-linked serum albumin scaffold	3
The effect of liver donors’ age, gender and metabolic state on pancreatic lineage activation	3
Mending the gaps: ethically sensitive cells and the evolution of European stem cell policy	3
Efficacy of adipose-derived stromal vascular fraction cells in the management of chronic ulcers: a randomized clinical trial	3
Analysis of GMP for marketing authorization of ATMPs: comparison in the US, the EU, Japan and South Korea	2
Ultrasound-guided injection of platelet-rich plasma or cord blood platelet-rich plasma in nonunion: a randomized controlled trial	2
The role of osteoarthritis severity, BMI and age on clinical efficacy of bone marrow aspirate concentrate in the treatment of knee osteoarthritis	2
Hypoxia-induced mesenchymal stem cells inhibit corneal fibroblast proliferation by regulating the WWP2/Notch1 axis	2
Development of a student-driven undergraduate program in regenerative medicine	2
The presence of sensational language describing stem cell therapies in news articles: a cross-sectional analysis	2
Derivation of a clinical decision rule for a bone marrow aspirate concentrate injection in knee osteoarthritis	2
Eliminating non-healing wounds: a review	2
Natural recovery and regeneration of the central nervous system	2
Combined adipose mesenchymal stromal cell advanced therapy resolved a recalcitrant leg ulcer in an 85-year-old patient	2
Stem-cell clinics in the UK: a web-based study	2
Industry updates from the field of stem cell research and regenerative medicine in November 2020	2
Industry updates from the field of stem cell research and regenerative medicine in February 2022	2

Priming mesenchymal stromal cells with neurotrophic factors boosts the neuro-regenerative potential of their secretome	2
Cellular transplantation and platelet-rich plasma injections for discogenic pain: a contemporary review	2
Endometriosis stem cell sources and potential therapeutic targets: literature review and bioinformatics analysis	2
Growth factors: avenues for the treatment of myocardial infarction and potential delivery strategies	2
EGFL7 affects the migration of epidermal stem cells in refractory diabetic wounds by regulating Notch signaling pathway	2
Industry updates from the field of stem cell research and regenerative medicine in January 2020: Industry News	2
The role of gene therapy as a valuable treatment modality for multiple spinal pathologies	2
Advances in regenerative dentistry; building with biology	2
Engineered cells along with smart scaffolds: critical factors for improving tissue engineering approaches	2
Mucoid degeneration of the anterior cruciate ligament: can platelet-rich plasma combined with reductionplasty provide better results?	2
Identification of regeneration-involved growth factors in cartilage engineering procedure promotes its reconstruction	2
Subchondral versus intra-articular orthobiologic injections for the treatment of knee osteoarthritis: a review	2
Keeping an eye on sustainable regeneration	2
Photoactivated leucocyte-rich platelet-rich plasma treatment in reduction of bone marrow edema in hip osteoarthritis	2
Phenotypic assessment of liver-derived cell cultures during in vitro expansion	2
Development of a closed and automated bioreactor technology for cell therapy manufacturing – a sharing of our journey	2
Bone tissue engineering in the greater omentum with computer-aided design/computer-aided manufacturing scaffolds is enhanced by a periosteum transplant	2
The efficacy of platelet-rich plasma in osseous foot and ankle pathology: a review	2
The advances of blood clots used as biomaterials in regenerative medicine	2
Effect of decellularization using sodium dodecyl sulfate on glycosaminoglycans content in the liver	2
Treatment of COVID-19 by stage: any space left for mesenchymal stem cell therapy?	2
Photobiomodulation of inflamed dental pulp stem cells under different nutritional conditions	2
Mechanical, topographical and chemical cues combined with physical therapy for peripheral nerve injuries	2