OOIR: Observatory of International Research

Papers

(The H4-Index of Expert Opinion on Drug Discovery is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Artificial intelligence in drug discovery: recent advances and future perspectives	123
Challenges identifying efficacious miRNA therapeutics for cancer	102
Open access in silico tools to predict the ADMET profiling of drug candidates	92
What is the current value of MM/PBSA and MM/GBSA methods in drug discovery?	87
Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery	71
The importance of sulfur-containing motifs in drug design and discovery	61
Artificial intelligence, machine learning, and drug repurposing in cancer	59
Nanonization techniques to overcome poor water-solubility with drugs	55
Metallo therapeutics for COVID-19. Exploiting metal-based compounds for the discovery of new antiviral drugs	53
How do we address neglected sulfur pharmacophores in drug discovery?	47
The power of deep learning to ligand-based novel drug discovery	44
An up-to-date overview of computational polypharmacology in modern drug discovery	41
Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade	41
Bi-phasic dose response in the preclinical and clinical developments of sigma-1 receptor ligands for the treatment of neurodegenerative disorders	38
Knowledge graphs and their applications in drug discovery	38
Discovery of CFTR modulators for the treatment of cystic fibrosis	37
An overview of rational design of mRNA-based therapeutics and vaccines	36
Targeting the Wnt/β-catenin pathway in neurodegenerative diseases: recent approaches and current challenges	35
Advances of droplet-based microfluidics in drug discovery	34
Assigning confidence to molecular property prediction	33
Artificial intelligence in early drug discovery enabling precision medicine	33
How necessary are animal models for modern drug discovery?	32
Strategies for targeting undruggable targets	31
Applications of fluorine to the construction of bioisosteric elements for the purposes of novel drug discovery	30
Advances in cell-based permeability assays to screen drugs for intestinal absorption	30

An update on the importance of plasma protein binding in drug discovery and development	29
Current models of pulmonary fibrosis for future drug discovery efforts	29
The application of machine learning techniques to innovative antibacterial discovery and development	29
Electrophilic warheads in covalent drug discovery: an overview	28
Fluorinated scaffolds for antimalarial drug discovery	28